KR102122429B1 - 세포독성 디펩티드의 동결건조 제제 - Google Patents
세포독성 디펩티드의 동결건조 제제 Download PDFInfo
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- KR102122429B1 KR102122429B1 KR1020207003073A KR20207003073A KR102122429B1 KR 102122429 B1 KR102122429 B1 KR 102122429B1 KR 1020207003073 A KR1020207003073 A KR 1020207003073A KR 20207003073 A KR20207003073 A KR 20207003073A KR 102122429 B1 KR102122429 B1 KR 102122429B1
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- melphalan flufenamide
- delete delete
- solution
- lyophilized
- cyclodextrin
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Mechanical Engineering (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1150371-1 | 2011-04-28 | ||
| SE1150371 | 2011-04-28 | ||
| US201161535126P | 2011-09-15 | 2011-09-15 | |
| US61/535,126 | 2011-09-15 | ||
| PCT/EP2012/057577 WO2012146625A1 (en) | 2011-04-28 | 2012-04-25 | Lyophilized preparation of cytotoxic dipeptides |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020177035122A Division KR102122416B1 (ko) | 2011-04-28 | 2012-04-25 | 세포독성 디펩티드의 동결건조 제제 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20200014947A KR20200014947A (ko) | 2020-02-11 |
| KR102122429B1 true KR102122429B1 (ko) | 2020-06-12 |
Family
ID=69569109
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020207003073A KR102122429B1 (ko) | 2011-04-28 | 2012-04-25 | 세포독성 디펩티드의 동결건조 제제 |
| KR1020207016300A KR102194376B1 (ko) | 2011-04-28 | 2012-04-25 | 세포독성 디펩티드의 동결건조 제제 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020207016300A KR102194376B1 (ko) | 2011-04-28 | 2012-04-25 | 세포독성 디펩티드의 동결건조 제제 |
Country Status (8)
| Country | Link |
|---|---|
| KR (2) | KR102122429B1 (es) |
| ES (1) | ES2813979T3 (es) |
| HK (1) | HK1250492A1 (es) |
| HR (1) | HRP20201300T1 (es) |
| HU (1) | HUE051690T4 (es) |
| IL (1) | IL280812B2 (es) |
| LT (1) | LT3228319T (es) |
| PT (1) | PT3228319T (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230398069A1 (en) * | 2020-08-19 | 2023-12-14 | Cellact Pharma Gmbh | Etoposide toniribate formulation |
| JP2024517762A (ja) * | 2021-04-28 | 2024-04-23 | インチョン ナショナル ユニバーシティ リサーチ アンド ビジネス ファウンデーション | 細胞外小胞の凍結乾燥保護剤 |
| EP4233837A1 (en) * | 2022-02-24 | 2023-08-30 | CellAct Pharma GmbH | Solid and oral etoposide toniribate compositions |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040034099A1 (en) | 2002-06-27 | 2004-02-19 | Ramsey Beverly J. | Pharmaceutical composition |
| US20040097421A1 (en) | 2000-06-13 | 2004-05-20 | Rolf Lewensohn | Melphalan derivatives and their use as cancer chemotherapeutic drugs |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0002202D0 (sv) * | 2000-06-13 | 2000-06-13 | Karolinska Innovations Ab | New peptides |
| US6780324B2 (en) * | 2002-03-18 | 2004-08-24 | Labopharm, Inc. | Preparation of sterile stabilized nanodispersions |
-
2012
- 2012-04-25 HU HUE17173249A patent/HUE051690T4/hu unknown
- 2012-04-25 IL IL280812A patent/IL280812B2/en unknown
- 2012-04-25 ES ES17173249T patent/ES2813979T3/es active Active
- 2012-04-25 KR KR1020207003073A patent/KR102122429B1/ko active IP Right Grant
- 2012-04-25 KR KR1020207016300A patent/KR102194376B1/ko active IP Right Grant
- 2012-04-25 LT LTEP17173249.8T patent/LT3228319T/lt unknown
- 2012-04-25 PT PT171732498T patent/PT3228319T/pt unknown
-
2018
- 2018-08-01 HK HK18109930.4A patent/HK1250492A1/zh unknown
-
2020
- 2020-08-20 HR HRP20201300TT patent/HRP20201300T1/hr unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040097421A1 (en) | 2000-06-13 | 2004-05-20 | Rolf Lewensohn | Melphalan derivatives and their use as cancer chemotherapeutic drugs |
| US20040034099A1 (en) | 2002-06-27 | 2004-02-19 | Ramsey Beverly J. | Pharmaceutical composition |
Non-Patent Citations (1)
| Title |
|---|
| J. Excipients and Food Chem. 1(1), 2010, 41-54 |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20200084890A (ko) | 2020-07-13 |
| KR20200014947A (ko) | 2020-02-11 |
| PT3228319T (pt) | 2020-08-27 |
| KR102194376B1 (ko) | 2020-12-23 |
| IL280812B2 (en) | 2023-04-01 |
| LT3228319T (lt) | 2020-09-25 |
| IL280812B (en) | 2022-12-01 |
| IL280812A (en) | 2021-04-29 |
| HUE051690T2 (hu) | 2021-03-29 |
| HUE051690T4 (hu) | 2023-09-28 |
| HK1250492A1 (zh) | 2018-12-21 |
| HRP20201300T1 (hr) | 2020-11-27 |
| ES2813979T3 (es) | 2021-03-25 |
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| CA2889753C (en) | Lyophilized preparations of melphalan flufenamide | |
| KR102122429B1 (ko) | 세포독성 디펩티드의 동결건조 제제 | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A107 | Divisional application of patent | ||
| E701 | Decision to grant or registration of patent right | ||
| GRNT | Written decision to grant |