KR102087373B1 - 비소세포성 폐암 진단용 단백질 바이오마커 패널 및 이를 이용한 비소세포성 폐암 진단 방법 - Google Patents

비소세포성 폐암 진단용 단백질 바이오마커 패널 및 이를 이용한 비소세포성 폐암 진단 방법 Download PDF

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KR102087373B1
KR102087373B1 KR1020207004010A KR20207004010A KR102087373B1 KR 102087373 B1 KR102087373 B1 KR 102087373B1 KR 1020207004010 A KR1020207004010 A KR 1020207004010A KR 20207004010 A KR20207004010 A KR 20207004010A KR 102087373 B1 KR102087373 B1 KR 102087373B1
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biomarker
lung cancer
aptamer
small cell
cell lung
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KR20200020958A (ko
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김윤동
석민경
정종하
에발다스 카틸리우스
도미닉 앤서니 지치
레이첼 엠. 오스트로프
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주식회사 압타머사이언스
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5752—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
    • G01N33/57423—
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G01N33/57488—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4737—C-reactive protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/7056—Selectin superfamily, e.g. LAM-1, GlyCAM, ELAM-1, PADGEM
    • G01N2333/70564—Selectins, e.g. CD62
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/988—Lyases (4.), e.g. aldolases, heparinase, enolases, fumarase

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020207004010A 2015-09-11 2015-09-11 비소세포성 폐암 진단용 단백질 바이오마커 패널 및 이를 이용한 비소세포성 폐암 진단 방법 Active KR102087373B1 (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2015/009552 WO2017043679A1 (en) 2015-09-11 2015-09-11 Protein biomarker panel for detecting non-small cell lung cancer and method for diagnosing a non-small cell lung cancer by the use thereof

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KR1020187007151A Division KR102078310B1 (ko) 2015-09-11 2015-09-11 비소세포성 폐암 진단용 단백질 바이오마커 패널 및 이를 이용한 비소세포성 폐암 진단 방법

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KR20200020958A KR20200020958A (ko) 2020-02-26
KR102087373B1 true KR102087373B1 (ko) 2020-03-10

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KR1020207004010A Active KR102087373B1 (ko) 2015-09-11 2015-09-11 비소세포성 폐암 진단용 단백질 바이오마커 패널 및 이를 이용한 비소세포성 폐암 진단 방법
KR1020187007151A Active KR102078310B1 (ko) 2015-09-11 2015-09-11 비소세포성 폐암 진단용 단백질 바이오마커 패널 및 이를 이용한 비소세포성 폐암 진단 방법

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JP (1) JP6857185B2 (https=)
KR (2) KR102087373B1 (https=)
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WO (1) WO2017043679A1 (https=)

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CN113348356A (zh) * 2018-11-20 2021-09-03 文塔纳医疗系统公司 用于针对形态学特征和生物标志物表达而制备和分析细胞样品的方法和系统
TWI758670B (zh) * 2018-12-24 2022-03-21 奎克生技光電股份有限公司 健康風險評估方法
CN110333341A (zh) * 2019-07-04 2019-10-15 浙江理工大学 一种基于蛋白质芯片技术鉴别丝织品文物样的方法
US12499535B2 (en) 2020-01-24 2025-12-16 The Regents Of The University Of California Retinal disease biomarker prediction by stacking slices of 3D OCT image to reshape into 2D image and applying trained feature extractor and CNN
JP7847652B2 (ja) * 2021-12-30 2026-04-17 ソマロジック オペレーティング カンパニー インコーポレイテッド タンパク質測定のための次世代シーケンシング
WO2024173602A2 (en) * 2023-02-14 2024-08-22 The Regents Of The University Of California Systems and methods for automated diagnosis of disease related risk factors in 3d biomedical imaging
WO2025166038A1 (en) * 2024-02-02 2025-08-07 Illumina, Inc. Improved aptamer detection techniques
CN119064600B (zh) * 2024-11-04 2025-01-24 中国科学院生物物理研究所 用于非小细胞肺癌诊断的细胞外囊泡生物标志物及其应用
CN119595908B (zh) * 2024-12-13 2025-10-17 四川大学华西医院 金属离子介导的dna功能纳米机器开关用于双标志物同时检测的分析方法

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WO2010030697A1 (en) 2008-09-09 2010-03-18 Somalogic, Inc. Lung cancer biomarkers and uses thereof
WO2013062516A1 (en) 2011-10-24 2013-05-02 Hewlett-Packard Development Company, L.P. Fluid ejection devices and methods thereof
WO2013062515A2 (en) 2011-10-24 2013-05-02 Somalogic, Inc. Lung cancer biomarkers and uses thereof
WO2013152989A2 (en) 2012-04-10 2013-10-17 Eth Zurich Biomarker assay and uses thereof for diagnosis, therapy selection, and prognosis of cancer

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US7371818B2 (en) * 2000-12-28 2008-05-13 Shionogi & Co., Ltd. Polypeptide and DNA thereof
US7888051B2 (en) * 2007-09-11 2011-02-15 Cancer Prevention And Cure, Ltd. Method of identifying biomarkers in human serum indicative of pathologies of human lung tissues
KR101810799B1 (ko) * 2008-02-01 2017-12-19 더 제너럴 하스피탈 코포레이션 의학적 질환 및 병태의 진단, 예후, 및 치료에 있어서 미세소포체의 용도
CN108181457B (zh) * 2009-03-12 2021-03-30 癌症预防和治疗有限公司 鉴定、评估、预防以及治疗肺疾病的方法及试剂盒
SG168431A1 (en) * 2009-07-23 2011-02-28 Univ Singapore Cancer biomarker and the use thereof
CA2769406A1 (en) * 2009-08-04 2011-02-10 Biosystems International Sas Lung cancer biomarkers
EP2542696B1 (en) * 2010-03-01 2016-09-28 Caris Life Sciences Switzerland Holdings GmbH Biomarkers for theranostics
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JP2014519340A (ja) * 2011-06-16 2014-08-14 カリス ライフ サイエンシズ ルクセンブルク ホールディングス エス．アー．エール．エル． バイオマーカー組成物および方法
KR20140067001A (ko) * 2011-08-08 2014-06-03 카리스 라이프 사이언스 룩셈부르크 홀딩스, 에스.에이.알.엘. 생물지표 조성물 및 방법
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WO2010030697A1 (en) 2008-09-09 2010-03-18 Somalogic, Inc. Lung cancer biomarkers and uses thereof
WO2013062516A1 (en) 2011-10-24 2013-05-02 Hewlett-Packard Development Company, L.P. Fluid ejection devices and methods thereof
WO2013062515A2 (en) 2011-10-24 2013-05-02 Somalogic, Inc. Lung cancer biomarkers and uses thereof
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WO2013152989A2 (en) 2012-04-10 2013-10-17 Eth Zurich Biomarker assay and uses thereof for diagnosis, therapy selection, and prognosis of cancer

Also Published As

Publication number Publication date
CN108026584A (zh) 2018-05-11
JP2018528441A (ja) 2018-09-27
CN108026584B (zh) 2021-12-10
JP6857185B2 (ja) 2021-04-14
WO2017043679A1 (en) 2017-03-16
KR102078310B1 (ko) 2020-02-19
KR20200020958A (ko) 2020-02-26
KR20180036787A (ko) 2018-04-09

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