KR102074483B1 - Cosmetic composition using natural bittern and platinum ion water - Google Patents

Abstract

The present invention relates to a cosmetic composition for skin moisturizing, containing a platinum mixture of an aged bittern solution and platinum ionized water as an active ingredient. The platinum mixture of the present invention has an excellent effect of enhancing the expression of moisturizing-related factors, and thus may be favorably used as a moisturizing cosmetic material.

Description

Cosmetic composition using natural liver water and platinum ionized water {Cosmetic composition using natural bittern and platinum ion water}

The present invention relates to a skin moisturizing cosmetic composition containing a platinum mixture obtained by mixing a water aging solution with platinum ionized water as an active ingredient.

The skin is an organ that covers the outside and has a barrier function that protects the body from body temperature control and various external stimuli and prevents moisture from the inside. The epidermal layer of the skin is divided into stratum corneum, stratum granulosum, polar layer (stratum spinosum) and stratum basale in order from the outside, and the cells of the stratum corneum act like bricks, Intercellular lipids between keratinocytes act as a mortar, forming the skin barrier. In addition, the keratinocytes of healthy people have a high concentration of natural moisturizing factor (NMF), which plays an important role in moisturizing the skin by maintaining flexibility and of maintaining proper moisture.

As of nowadays, artificial temperature control of cooling / heating according to the change of environment and life pattern, skin stress caused by various stresses and environmental pollution that occur in social life, frequent face wash due to makeup habits and natural skin with age increase Due to various causes such as aging, the moisture of the stratum corneum decreases, the skin is dried, the surface is rough, and the skin becomes crumbly, loses moisture, and the appearance of lifelessness is increasing.

Korean Patent No. 0904200 discloses a skin moisturizing cosmetic composition containing honey leaf extract and aloe vera extract, and Korean Patent No. 1956553 includes a nanoemulsion containing a wild ginseng cultured fermentation extract as an active ingredient. Although the cosmetic composition for skin moisturizing is disclosed, it is different from the cosmetic composition using natural liver water and platinum ionized water of this invention.

The present invention is derived from the above requirements, the present inventors added the kelp, wall paulownia leaves and yew tree fruit to the brine, and then left to stand after the aging liquid prepared by mixing the platinum mixture with platinum ion water effect By confirming that, this invention was completed.

In order to solve the above problems, the present invention is a cosmetic composition for moisturizing skin containing a platinum mixture of a mixed fermentation broth and platinum ionized water prepared by adding kelp, wall paulownia leaves and yew fruit to the liver as an active ingredient To provide.

Since the platinum mixture of the present invention has excellent skin moisturizing effect, it can be usefully used as a material of cosmetics for improving or promoting skin moisturizing.

In order to achieve the object of the present invention, the present invention is for moisturizing the skin containing a platinum mixture of a mixed fermentation broth and platinum ion water prepared by adding kelp, wall paulownia leaves and yew tree fruit to the ganja as an active ingredient It provides a cosmetic composition.

In the skin moisturizing cosmetic composition of the present invention, the platinum mixture may be a mixture of fermentation broth and platinum ionized water in a volume ratio of 7.5 to 8.5: 1.5 to 2.5, more preferably the fermentation broth and platinum Ion water may be mixed at a volume ratio of 8: 2.

In addition, in the cosmetic composition for skin moisturizing of the present invention, the water aging solution is preferably added to 45 ~ 55 g kelp, 8 ~ 12 g of paulownia leaves and 8 ~ 12 g of yew leaves to 0.8 ~ 1.2 L After it may be prepared for 20 to 28 hours at 20 ~ 25 ℃, it may be prepared, more preferably at 20 ~ 25 ℃ after adding 50 g of kelp, 10 g of paulownia leaves and 10 g of yew leaves to 1 L of brine It may be prepared by leaving for 24 hours.

The term 'skin moisturizing' effect of the present invention refers to inhibiting or inhibiting the decrease in moisture of the skin or increasing the moisture content of the skin to smooth the skin surface and to give a shine. Or it means to maintain the homeostasis of the living body by appropriately adjusting the water loss (moisture evaporation).

The cosmetic composition of the present invention may be prepared in any formulation commonly prepared in the art, for example, solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, oils, powder foundations, emulsions It can be formulated as a liquid foundation, wax foundation, spray, and the like, and more specifically, skin, skin softener, skin toner, astringent, lotion, milk lotion, moisturizing lotion, nourishing lotion, massage cream, nourishing cream, eye cream , Moisturizing cream, hand cream, essence, nutrition essence, pack, cleansing foam, cleansing water, cleansing lotion, cleansing cream, body lotion, body cleanser, soap or powder cosmetic formulations, but is not limited thereto.

In case the formulation of the cosmetic composition of the present invention is a paste, cream or gel, the carrier component is animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide. This can be used.

When the formulation of the cosmetic composition of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as the carrier component, and in particular, in the case of a spray, additionally chlorofluoro hydro Propellant such as carbon, propane / butane or dimethyl ether.

When the formulation of the cosmetic composition of the present invention is a solution or emulsion, a solvent, solubilizing agent or emulsifying agent is used as the carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene. Fatty acid esters of glycol, 1,3-butylglycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan.

When the formulation of the cosmetic composition of the present invention is a suspension, a liquid diluent such as water, ethanol or propylene glycol, suspending agents such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester as carrier components , Microcrystalline cellulose, aluminum metahydroxy, bentonite, agar or tracant and the like can be used.

The cosmetic composition of the present invention includes components conventionally used in cosmetic compositions in addition to the active ingredient, and include, for example, fatty substances, organic solvents, solubilizers, thickeners and gelling agents, softeners, antioxidants, suspending agents, stabilizers, foaming agents ( foaming agents), fragrances, surfactants, water, ionic or nonionic emulsifiers, fillers, metal ion sequestrants and chelating agents, preservatives, vitamins, blocking agents, wetting agents, essential oils, dyes, pigments, hydrophilic or lipophilic active agents , Conventional adjuvants such as lipid vesicles, and carriers.

Hereinafter, the present invention will be described in detail by way of examples. However, the following examples are merely to illustrate the invention, but the content of the present invention is not limited to the following examples.

Example  1. Platinum mixture

(1) Raw water pretreated in three stages using a carbon filter (activated carbon), a USF filter (hollow fiber membrane filter) and a reverse osmosis membrane filter (RO membrane filter) in an electrolytic cell equipped with a platinum electrode as an anode, a platinum electrode as an anode, and an ion selective diaphragm. After the injection, a current of 2 A was flowed into the electrolytic cell to perform electrolysis. Thereafter, ionized water at the anode side was taken. Then, 500 mg of platinum particles and 1 L of the ionized water were mixed to prepare platinum ionized water.

(2) natural brine (Samsung Co.), kelp in 1 L 50 g, byeokohdong (Firmiana simplex) leaves 10 g and note tree (Taxus After adding 10 g of cuspidata ) fruit, the mixture was left at 20-25 ° C. for 24 hours to prepare a brine solution.

(3) The prepared platinum ionized water of step (1) and the prepared brine aging solution of step (2) were mixed at an 8: 2 volume ratio.

Water aging liquid mixture ratio Material type Example 1 Comparative Example 1 Comparative Example 2 Comparative Example 3 Natural water 1 L 1 L 1 L 1 L Kelp 50 g 70 g 50 g 50 g Paulownia leaves 10 g - 20 g - Yew tree fruit 10 g - - 20 g

Comparative example  1 to 3. Platinum mixture

A platinum mixture was prepared by the method of Example 1, but the ingredients were prepared in the mixing ratio of Table 1 to prepare the mixture of Comparative Examples 1 to 3, respectively.

Example  2. Preparation of flexible lotion

A flexible lotion containing the platinum mixture of the present invention as an active ingredient was prepared.

Specifically, 10.00 parts by weight of the platinum mixture, 1.00 parts by weight of 1,3-butylene glycol, 0.05 parts by weight of disodium ethane, 0.10 parts by weight of allantoin, 0.05 parts by weight of dipotassium glycylizate, and 0.01 parts by weight of citric acid Part, 0.02 parts by weight of sodium citrate, 1.00 parts by weight of glycerin-26, 2.00 parts by weight of arbutin, 1.00 parts by weight of hydrogenated castor oil, 30.00 parts by weight of ethanol, preservatives, traces of coloring and flavoring agents, and the remaining amount of purified water Flexible cosmetics were prepared.

Experimental Example  1. Assessment of Cytotoxicity of Platinum Mixtures

Prior to assessing the skin moisturizing efficacy of the platinum mixture, the cytotoxicity of the mixture was analyzed. HaCaT cells, which are human keratinocyte cells, were treated by diluting samples for 24 hours by concentration, followed by MTS assay (CellTiter Aqueous One Solution Cell proliferation assay kit 3- (4,5-dimethylthiazol-2). -yl) -5- (3-carboxymethoxyphenyl) -2- (4-sulfophynyl) -2H-tetrazolium, inner salt; MTS, Promega Co. Madison, WI, USA) technique for cell viability at 490 nm Molecular Devices, Sunnyvale, CA, USA).

% Cell viability following treatment of platinum mixture division Control Platinum Mixture of Example 1 (μg / mL) 100 200 300 Cell survival rate (%) 100 102.6 98.3 104.5

As a result, as shown in Table 2, even when the platinum mixture of the present invention was treated, there was almost no change in cell viability (%) relative to the control group treated with nothing, and the platinum mixture of the present invention showed no cytotoxicity. It was confirmed.

Experimental Example  2. Hyaluronic acid ( Hyaluronic  Acid; Analysis of content change of HA)

Each HaCaT cell was treated with each sample for 24 hours and irradiated with UV (UV Crosslinker, Ultra Lum) at 20 mJ / cm ² for 30 minutes, and then the supernatant of the culture was collected to obtain a hyaluronic acid ELISA kit (R & D Systems, Inc., Minneapolis, MN, USA) was used to determine the content of HA. The reaction was subjected to an absorbance assay.

As a result, as shown in Table 3, the content of hyaluronic acid was decreased by ultraviolet irradiation (UVB), but the content of hyaluronic acid was increased in each experimental group treated with the platinum mixture (100 ug / ml) of the present invention. It confirmed that it increased. The experimental group treated with the platinum mixture of Example 1 showed the highest hyaluronic acid content.

Hyaluronic Acid Content Changes by Platinum Mixture Treatment (ng / ml) division Hyaluronic Acid Content (ng / ml) Control 4.7 UVB 0.8 Example 1 3.6 Comparative Example 1 3.0 Comparative Example 2 3.1 Comparative Example 3 2.9

Control: Voice Control (No UV)

Experimental Example  3. Feeling  evaluation

The moisture content and the water loss amount according to the skin application of the flexible lotion prepared by the method of Example 2 were investigated for 3 weeks. The flexible lotion was prepared by preparing the flexible lotion by the method of Example 2, but adding the platinum mixture of Example 1 and Comparative Examples 1 to 3 when the platinum mixture was added. The water content test was conducted to measure the skin water content of 10 test subjects on the cheeks (use) and the opposite cheeks (unused) using essence. The water loss test was also shown by averaging 10 test subjects by measuring the amount of skin water loss on the cheeks (used) and the opposite cheeks (unused).

Usability evaluation Sample type Capacitance (AU)
Water content (㎍ / cm ² ) Water loss amount (TEWL) (g / hm ² ) Example 1 No use 48.55 20.21 use 65.58 11.20 Comparative Example 1 No use 49.22 19.08 use 60.25 13.58 Comparative Example 2 No use 49.12 19.58 use 56.25 14.90 Comparative Example 3 No use 50.10 20.02 use 57.20 14.20

As a result, it was confirmed that the ball containing the platinum mixture-added lotion of Example 1 and Comparative Examples had a higher water content than the ball which was not used, and among them, the use of the platinum mixture-added lotion of Example 1 had the highest water content. It was confirmed that the moisture loss amount was the lowest.

Claims (4)

45-55 g of kelp, 8-12 g of paulownia leaves, and 8-12 g of yew tree fruits were added to 0.8-1.2 L of brine, and the fermentation broth and platinum ionized water were left at 20-25 ° C for 20-28 hours. Skin moisturizing cosmetic composition containing a platinum mixture of 7.5 to 8.5: 1.5 to 2.5 by volume ratio as an active ingredient. delete delete According to claim 1, wherein the cosmetic composition is a skin, skin softener, skin toner, astringent, lotion, milk lotion, moisturizing lotion, nutrition lotion, massage cream, nutrition cream, eye cream, moisture cream, hand cream, essence, nutrition Essence, pack, cleansing foam, cleansing water, cleansing lotion, cleansing cream, body lotion, body cleanser, soap and powder, characterized in that the cosmetic composition for moisturizing the skin, characterized in that it is prepared in any one formulation.