KR102065543B1 - 메틸 4-아미노-3-클로로-6-(4-클로로-2-플루오로-3-메톡시페닐)피리딘-2-카르복실레이트의 제조 방법 - Google Patents
메틸 4-아미노-3-클로로-6-(4-클로로-2-플루오로-3-메톡시페닐)피리딘-2-카르복실레이트의 제조 방법 Download PDFInfo
- Publication number
- KR102065543B1 KR102065543B1 KR1020147020894A KR20147020894A KR102065543B1 KR 102065543 B1 KR102065543 B1 KR 102065543B1 KR 1020147020894 A KR1020147020894 A KR 1020147020894A KR 20147020894 A KR20147020894 A KR 20147020894A KR 102065543 B1 KR102065543 B1 KR 102065543B1
- Authority
- KR
- South Korea
- Prior art keywords
- chloro
- fluoro
- methyl
- carboxylate
- methoxyphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/803—Processes of preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161582166P | 2011-12-30 | 2011-12-30 | |
| US61/582,166 | 2011-12-30 | ||
| PCT/US2012/072071 WO2013102078A1 (en) | 2011-12-30 | 2012-12-28 | Methods of producing methyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20140117444A KR20140117444A (ko) | 2014-10-07 |
| KR102065543B1 true KR102065543B1 (ko) | 2020-01-13 |
Family
ID=48695351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020147020894A Active KR102065543B1 (ko) | 2011-12-30 | 2012-12-28 | 메틸 4-아미노-3-클로로-6-(4-클로로-2-플루오로-3-메톡시페닐)피리딘-2-카르복실레이트의 제조 방법 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8754110B2 (https=) |
| EP (1) | EP2797890B1 (https=) |
| JP (1) | JP6092250B2 (https=) |
| KR (1) | KR102065543B1 (https=) |
| AR (1) | AR089628A1 (https=) |
| AU (1) | AU2012362268B2 (https=) |
| BR (1) | BR112014015962B8 (https=) |
| CA (1) | CA2861611C (https=) |
| CO (1) | CO7010843A2 (https=) |
| IL (1) | IL233412B (https=) |
| IN (1) | IN2014DN05767A (https=) |
| MX (1) | MX340947B (https=) |
| NZ (1) | NZ627192A (https=) |
| PL (1) | PL2797890T3 (https=) |
| RU (1) | RU2616621C2 (https=) |
| WO (1) | WO2013102078A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2797933T3 (pl) * | 2011-12-30 | 2018-01-31 | Dow Agrosciences Llc | Sposoby wytwarzania estrów pinakolowych kwasu 4-chloro-2-fluoro-3-podstawionego-fenyloboronowego oraz sposoby ich stosowania |
| US20140170058A1 (en) * | 2012-12-13 | 2014-06-19 | Dow Agrosciences Llc | Process for the removal of palladium from 4-amino-3-halo-5-fluoro-6-(aryl) pyridine-2-carboxylates and 4-amino-3-halo-6-(aryl)pyridine-2-carboxylates |
| BR102014021960A2 (pt) | 2013-09-05 | 2015-09-15 | Univ Michigan State | métodos para a produção de arenos borilados |
| TW201625354A (zh) | 2014-06-16 | 2016-07-16 | 陶氏農業科學公司 | 用於製備氧硼基化芳烴之方法 |
| BR112017019207A2 (pt) * | 2015-05-22 | 2018-04-24 | Dow Agrosciences Llc | recuperação e/ou reutilização de catalisador de paládio após acoplamento de suzuki |
| CN105851037B (zh) * | 2016-05-17 | 2018-09-07 | 陕西上格之路生物科学有限公司 | 一种含氟氯吡啶酯的三元除草组合物 |
| US10087164B2 (en) * | 2016-05-19 | 2018-10-02 | Dow Agrosciences Llc | Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct Suzuki coupling |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011509300A (ja) * | 2008-01-11 | 2011-03-24 | ダウ アグロサイエンシィズ エルエルシー | １−フルオロ−２−置換−３−クロロベンゼンの選択的脱プロトン化及び官能化の方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7145040B2 (en) * | 2004-07-02 | 2006-12-05 | Bristol-Myers Squibb Co. | Process for the preparation of amino acids useful in the preparation of peptide receptor modulators |
| CA2626018C (en) | 2006-01-13 | 2014-05-06 | Dow Agrosciences Llc | 2-(poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides |
| EP2060566B1 (en) * | 2006-01-13 | 2016-06-08 | Dow AgroSciences LLC | Poly-substituted aryls |
| CA2699598C (en) * | 2007-10-02 | 2013-05-21 | Dow Agrosciences Llc | 2-substituted-6-amino-5-alkyl, alkenyl or alkynyl-4-pyrimidinecarboxylic acids and 6-substituted-4-amino-3-alkyl, alkenyl or alkynyl picolinic acids and their use as herbicides |
| GB0902474D0 (en) * | 2009-02-13 | 2009-04-01 | Syngenta Ltd | Chemical compounds |
| US8252938B2 (en) * | 2009-06-08 | 2012-08-28 | Dow Agrosciences, Llc. | Process for the preparation of 6-(aryl)-4-aminopicolinates |
| CN102612512A (zh) * | 2009-11-19 | 2012-07-25 | 莱西肯医药有限公司 | 取代的苯丙氨酸的制备方法 |
| PL2797933T3 (pl) * | 2011-12-30 | 2018-01-31 | Dow Agrosciences Llc | Sposoby wytwarzania estrów pinakolowych kwasu 4-chloro-2-fluoro-3-podstawionego-fenyloboronowego oraz sposoby ich stosowania |
| US20140170058A1 (en) * | 2012-12-13 | 2014-06-19 | Dow Agrosciences Llc | Process for the removal of palladium from 4-amino-3-halo-5-fluoro-6-(aryl) pyridine-2-carboxylates and 4-amino-3-halo-6-(aryl)pyridine-2-carboxylates |
-
2012
- 2012-12-28 RU RU2014131451A patent/RU2616621C2/ru active
- 2012-12-28 KR KR1020147020894A patent/KR102065543B1/ko active Active
- 2012-12-28 EP EP12862450.9A patent/EP2797890B1/en active Active
- 2012-12-28 IN IN5767DEN2014 patent/IN2014DN05767A/en unknown
- 2012-12-28 MX MX2014008019A patent/MX340947B/es active IP Right Grant
- 2012-12-28 AU AU2012362268A patent/AU2012362268B2/en active Active
- 2012-12-28 US US13/729,995 patent/US8754110B2/en active Active
- 2012-12-28 PL PL12862450T patent/PL2797890T3/pl unknown
- 2012-12-28 JP JP2014550511A patent/JP6092250B2/ja active Active
- 2012-12-28 NZ NZ627192A patent/NZ627192A/en unknown
- 2012-12-28 WO PCT/US2012/072071 patent/WO2013102078A1/en not_active Ceased
- 2012-12-28 CA CA2861611A patent/CA2861611C/en active Active
- 2012-12-28 BR BR112014015962A patent/BR112014015962B8/pt active IP Right Grant
-
2013
- 2013-01-02 AR ARP130100011A patent/AR089628A1/es active IP Right Grant
-
2014
- 2014-06-26 IL IL233412A patent/IL233412B/en active IP Right Grant
- 2014-07-18 CO CO14156063A patent/CO7010843A2/es unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011509300A (ja) * | 2008-01-11 | 2011-03-24 | ダウ アグロサイエンシィズ エルエルシー | １−フルオロ−２−置換−３−クロロベンゼンの選択的脱プロトン化及び官能化の方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6092250B2 (ja) | 2017-03-08 |
| EP2797890B1 (en) | 2016-10-05 |
| AU2012362268A1 (en) | 2014-07-31 |
| US8754110B2 (en) | 2014-06-17 |
| US20130172566A1 (en) | 2013-07-04 |
| IN2014DN05767A (https=) | 2015-04-10 |
| NZ627192A (en) | 2015-09-25 |
| CA2861611C (en) | 2020-04-21 |
| PL2797890T3 (pl) | 2017-06-30 |
| AU2012362268B2 (en) | 2016-11-17 |
| CO7010843A2 (es) | 2014-07-31 |
| RU2616621C2 (ru) | 2017-04-18 |
| MX340947B (es) | 2016-08-01 |
| BR112014015962A2 (pt) | 2017-06-13 |
| AR089628A1 (es) | 2014-09-03 |
| MX2014008019A (es) | 2014-12-08 |
| CA2861611A1 (en) | 2013-07-04 |
| EP2797890A4 (en) | 2015-09-23 |
| BR112014015962B1 (pt) | 2019-12-17 |
| RU2014131451A (ru) | 2016-02-20 |
| BR112014015962B8 (pt) | 2022-10-11 |
| JP2015504059A (ja) | 2015-02-05 |
| BR112014015962A8 (pt) | 2017-07-04 |
| IL233412A0 (en) | 2014-08-31 |
| KR20140117444A (ko) | 2014-10-07 |
| IL233412B (en) | 2019-01-31 |
| WO2013102078A1 (en) | 2013-07-04 |
| EP2797890A1 (en) | 2014-11-05 |
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| EP2797933B1 (en) | Methods of forming 4-chloro-2-fluoro-3-substituted-phenylboronic acid pinacol esters and methods of using the same | |
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