KR102047431B1 - 유동이 가역적인 균질화 공정 및 장치 - Google Patents
유동이 가역적인 균질화 공정 및 장치 Download PDFInfo
- Publication number
- KR102047431B1 KR102047431B1 KR1020157019873A KR20157019873A KR102047431B1 KR 102047431 B1 KR102047431 B1 KR 102047431B1 KR 1020157019873 A KR1020157019873 A KR 1020157019873A KR 20157019873 A KR20157019873 A KR 20157019873A KR 102047431 B1 KR102047431 B1 KR 102047431B1
- Authority
- KR
- South Korea
- Prior art keywords
- deflection
- homogenization
- interaction element
- fluid
- plugs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/421—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path
- B01F25/423—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path by means of elements placed in the receptacle for moving or guiding the components
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/44—Mixers in which the components are pressed through slits
- B01F25/441—Mixers in which the components are pressed through slits characterised by the configuration of the surfaces forming the slits
- B01F25/4412—Mixers in which the components are pressed through slits characterised by the configuration of the surfaces forming the slits the slits being formed between opposed planar surfaces, e.g. pushed again each other by springs
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- B01F5/0663—
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/44—Mixers in which the components are pressed through slits
- B01F25/442—Mixers in which the components are pressed through slits characterised by the relative position of the surfaces during operation
- B01F25/4422—Mixers in which the components are pressed through slits characterised by the relative position of the surfaces during operation the surfaces being maintained in a fixed but adjustable position, spaced from each other, therefore allowing the slit spacing to be varied
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/44—Mixers in which the components are pressed through slits
- B01F25/442—Mixers in which the components are pressed through slits characterised by the relative position of the surfaces during operation
- B01F25/4423—Mixers in which the components are pressed through slits characterised by the relative position of the surfaces during operation the surfaces being part of a valve construction, formed by opposed members in contact, e.g. automatic positioning caused by spring pressure
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
- B01F35/71805—Feed mechanisms characterised by the means for feeding the components to the mixer using valves, gates, orifices or openings
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- B01F5/068—
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- B01F5/0681—
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Disintegrating Or Milling (AREA)
- General Preparation And Processing Of Foods (AREA)
- Seeds, Soups, And Other Foods (AREA)
- Beans For Foods Or Fodder (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Detergent Compositions (AREA)
- Fats And Perfumes (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Soy Sauces And Products Related Thereto (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000090A ITPR20120090A1 (it) | 2012-12-21 | 2012-12-21 | Procedimento e apparato di omogeneizzazione con inversione flusso |
| ITPR2012A000090 | 2012-12-21 | ||
| PCT/IB2013/061179 WO2014097234A2 (en) | 2012-12-21 | 2013-12-20 | Homogenising process and apparatus with flow reversal |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20150096803A KR20150096803A (ko) | 2015-08-25 |
| KR102047431B1 true KR102047431B1 (ko) | 2019-12-02 |
Family
ID=47605665
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157019873A Active KR102047431B1 (ko) | 2012-12-21 | 2013-12-20 | 유동이 가역적인 균질화 공정 및 장치 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10159946B2 (enExample) |
| EP (1) | EP2934733B1 (enExample) |
| JP (1) | JP2016501720A (enExample) |
| KR (1) | KR102047431B1 (enExample) |
| CN (1) | CN104884153B (enExample) |
| BR (1) | BR112015014958B1 (enExample) |
| CA (1) | CA2895182C (enExample) |
| DK (1) | DK2934733T3 (enExample) |
| ES (1) | ES2607486T3 (enExample) |
| IT (1) | ITPR20120090A1 (enExample) |
| RU (1) | RU2621768C2 (enExample) |
| WO (1) | WO2014097234A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3291684T3 (en) * | 2015-04-30 | 2019-04-15 | Gea Mech Equipment Italia S P A | PROCEDURE FOR YOGURT MANUFACTURING OR ANOTHER FERMENTED MILK BASED PRODUCT |
| US11332375B2 (en) | 2015-09-25 | 2022-05-17 | Lg Chem, Ltd. | Peeling device of sheet material including optimized outlet |
| JP6614554B2 (ja) * | 2016-11-15 | 2019-12-04 | 株式会社スギノマシン | ノズル洗浄方法及び微粒化装置のノズル洗浄構造 |
| CN109395666B (zh) * | 2018-12-20 | 2023-09-26 | 中原工学院 | 一体化的对射流型反应器 |
| IT202000007159A1 (it) * | 2020-04-03 | 2021-10-03 | Gea Mech Equipment Italia S P A | Metodo di validazione di una valvola omogeneizzante |
| CN115614484B (zh) * | 2022-10-28 | 2025-05-23 | 上海申鹿均质机有限公司 | 一种对撞式均质阀结构 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE361642C (de) * | 1922-10-17 | Bergedorfer Eisenwerk Akt Ges | Homogenisiervorrichtung | |
| DE271432C (enExample) * | ||||
| FR17429E (fr) * | 1913-08-30 | John Henry Exshaw Cessionnaire | Obturateur pour conduites et appareils dans lesquels circulent tous fluides, gaz, vapeurs ou liquides | |
| NL48062C (enExample) | 1938-03-11 | 1939-10-16 | ||
| US2236013A (en) * | 1939-07-17 | 1941-03-25 | American Marsh Pumps Inc | Homogenizer |
| US2274720A (en) * | 1939-07-29 | 1942-03-03 | Marco Company Inc | Combinator head or homogenizer |
| US2662590A (en) * | 1947-07-14 | 1953-12-15 | Julius Vignati | Gas burner and flow restrictor |
| US3164167A (en) * | 1961-01-19 | 1965-01-05 | Albina Ets | Apparatus for homogenizing liquids and pulps |
| DE1258835B (de) | 1964-08-28 | 1968-01-18 | James R Lage Dr | Mischeinrichtung |
| DD122649A1 (enExample) * | 1975-09-10 | 1976-10-20 | ||
| US4135829A (en) * | 1977-08-24 | 1979-01-23 | International Telephone And Telegraph Corporation | Homogenizer |
| US4340311A (en) | 1980-09-26 | 1982-07-20 | Zebron Corporation | Interfacial surface generator mixer |
| DE8711740U1 (de) * | 1987-08-29 | 1987-12-23 | Bran & Lübbe GmbH, 22844 Norderstedt | Homogenisiervorrichtung |
| DE3818237A1 (de) * | 1988-05-28 | 1989-11-30 | Bran & Luebbe | Hochdruckhomogenisator |
| US4860959A (en) * | 1988-06-23 | 1989-08-29 | Semi-Bulk Systems, Inc. | Apparatus for subjecting particles dispersed in a fluid to a shearing action |
| US5217037A (en) * | 1991-11-26 | 1993-06-08 | Apv Gaulin, Inc. | Homogenizing apparatus having magnetostrictive actuator assembly |
| US5273407A (en) * | 1992-04-30 | 1993-12-28 | Apv Gaulin Gmbh | Homogenizing system having improved fluid flow path |
| CH685366A5 (fr) * | 1992-12-09 | 1995-06-30 | Nestle Sa | Dispositif de traitement d'un produit fluide par injection de vapeur. |
| US5482369A (en) * | 1993-02-08 | 1996-01-09 | Verstallen; Adrian | Process for homogenizing essentially immiscible liquids for forming an emulsion |
| GB9419520D0 (en) | 1994-09-28 | 1994-11-16 | Ic Consultants Limited | A mixer and apparatus for analysing fluid flow |
| IT1282765B1 (it) | 1996-05-30 | 1998-03-31 | Niro Soavi Spa | Valvola di omogeneizzazione |
| JP3149371B2 (ja) * | 1996-12-26 | 2001-03-26 | 株式会社ジーナス | 微粒化方法及びその装置 |
| JPH10180069A (ja) * | 1996-12-26 | 1998-07-07 | Jiinasu:Kk | 微粒化方法及びその装置 |
| US5984519A (en) | 1996-12-26 | 1999-11-16 | Genus Corporation | Fine particle producing devices |
| JPH1142428A (ja) | 1997-07-25 | 1999-02-16 | Jiinasu:Kk | 微粒化方法 |
| TW536425B (en) * | 2001-05-30 | 2003-06-11 | Cam Tecnologie S P A | A static mixer and a process for producing dispersions, in particular dispersions of liquid fuel with water |
| CA2584955C (en) | 2006-05-15 | 2014-12-02 | Sulzer Chemtech Ag | A static mixer |
| JP4893365B2 (ja) * | 2007-02-27 | 2012-03-07 | 株式会社明電舎 | マイクロバブル発生装置及びマイクロバブル発生システム |
| JP2010017623A (ja) * | 2008-07-09 | 2010-01-28 | Sanmaru Kikai Kogyo Kk | ホモジナイザー |
-
2012
- 2012-12-21 IT IT000090A patent/ITPR20120090A1/it unknown
-
2013
- 2013-12-20 EP EP13828857.6A patent/EP2934733B1/en active Active
- 2013-12-20 BR BR112015014958-8A patent/BR112015014958B1/pt active IP Right Grant
- 2013-12-20 CN CN201380067017.2A patent/CN104884153B/zh active Active
- 2013-12-20 JP JP2015548860A patent/JP2016501720A/ja active Pending
- 2013-12-20 US US14/651,314 patent/US10159946B2/en active Active
- 2013-12-20 ES ES13828857.6T patent/ES2607486T3/es active Active
- 2013-12-20 RU RU2015129450A patent/RU2621768C2/ru active
- 2013-12-20 WO PCT/IB2013/061179 patent/WO2014097234A2/en not_active Ceased
- 2013-12-20 DK DK13828857.6T patent/DK2934733T3/en active
- 2013-12-20 CA CA2895182A patent/CA2895182C/en active Active
- 2013-12-20 KR KR1020157019873A patent/KR102047431B1/ko active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US10159946B2 (en) | 2018-12-25 |
| RU2621768C2 (ru) | 2017-06-07 |
| CA2895182C (en) | 2020-01-21 |
| CN104884153B (zh) | 2017-06-06 |
| DK2934733T3 (en) | 2017-01-30 |
| WO2014097234A2 (en) | 2014-06-26 |
| CA2895182A1 (en) | 2014-06-26 |
| JP2016501720A (ja) | 2016-01-21 |
| EP2934733B1 (en) | 2016-11-09 |
| KR20150096803A (ko) | 2015-08-25 |
| ITPR20120090A1 (it) | 2014-06-22 |
| ES2607486T3 (es) | 2017-03-31 |
| EP2934733A2 (en) | 2015-10-28 |
| CN104884153A (zh) | 2015-09-02 |
| US20150298074A1 (en) | 2015-10-22 |
| BR112015014958B1 (pt) | 2021-07-20 |
| WO2014097234A3 (en) | 2014-10-16 |
| RU2015129450A (ru) | 2017-01-26 |
| BR112015014958A2 (pt) | 2017-07-11 |
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| Lieberman | Ultrasonic homogenizing systems are able to produce particle-size and droplet-size distributions that approach those of piston homogenizers with a lower power re-quirement. In order to work, they must be fed a well-blended premix or a metered feed of the liquid components. The vibrating element is an extra maintenance item, espe-cially in heavy or abrasive service. Overall, they offer an attractive option when fixed-gap rotor/stator devices do not produce the required size distributions. 5. Homogenizer/Extruder Another high-pressure homogenizer/extruder with an adjustable valve having produc-tion capacities from 8 mL/hr to 12,000 LL/hr is available. A positive displacement pump produces pressures up to 30,000 psig. The manufacturer claims that no O-ring is used in the product pass and pump seal, and this homogenizer/extruder was approved by the US Food and Drug Administration for pharmaceutical use [36]. At this writing, in-formation concerning the internal structure is not available. The apparatus is capable of producing fine emulsions and liposomal dispersions. Figure 36 shows a laboratory unit. 6. Microfluidizer Technologies A more recent invention to find wide use in specialized forms of dispersed system dosage forms is the microfluidizer. This device uses a high-pressure positive-displacement pump operating at a pressure of 500-20,000 psig, which accelerates the process flow to up to 500 m/min through the interaction chamber. The interaction chamber consists of small channels known as microchannels. The microchannel diameters can be as narrow as 50 urn and cause the flow of product to occur as very thin sheets. The configuration of these microchannels within the interaction chamber resembles Y-shaped flow streams in which the process stream divides into these microchannels, creating two separate microstreams. The sum of cross-sectional areas of these two microstreams is less than the cross-sectional area of the pipe before division to two separate streams. This nar-rowing of the flow pass creates an (axisymmetric) elongational flow to generate high Fig. 36 Emulsiflex-C5, a high-pressure homogenizer.(From Ref. 36.) | |
| CN113578487A (zh) | 一种射流喷头 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| E13-X000 | Pre-grant limitation requested |
St.27 status event code: A-2-3-E10-E13-lim-X000 |
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| PA0105 | International application |
St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
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| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| P22-X000 | Classification modified |
St.27 status event code: A-2-2-P10-P22-nap-X000 |
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| A201 | Request for examination | ||
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
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| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
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| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
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| E13-X000 | Pre-grant limitation requested |
St.27 status event code: A-2-3-E10-E13-lim-X000 |
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| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
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| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
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| PR0701 | Registration of establishment |
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| PR1002 | Payment of registration fee |
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| PG1601 | Publication of registration |
St.27 status event code: A-4-4-Q10-Q13-nap-PG1601 |
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| P22-X000 | Classification modified |
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