KR102036988B1 - Preparing method for capsulated female cleansing composition and capsulated female cleasing composition thereof - Google Patents

Abstract

The present invention, by inoculating a specific strain to rice bran extract to obtain natural rice bran fermentation composition powder with hypoallergenic anti-inflammatory function through the process of natural fermentation, by providing a capsule-type female detergent encapsulated, when used in sensitive areas of women It solves the problem of the female detergent composition containing the conventional chemical component which was highly irritating, and shows the functionality of hypoallergenicity, anti-inflammatory, etc. using natural materials, and is suitable for the female detergent use. In addition, the capsule-type female cleaner according to the present invention can be used in the form of inserting into the local, there is a feature that is easy to apply to the local (affected) and easy to carry.

Description

Manufacturing method of capsule-type female detergent and capsule-type female detergent manufactured according to the same {PREPARING METHOD FOR CAPSULATED FEMALE CLEANSING COMPOSITION AND CAPSULATED FEMALE CLEASING COMPOSITION THEREOF}

The present invention relates to a method for producing a capsule female cleanser and a capsule female cleanser prepared accordingly.

Female genitourinary organs are composed of ovaries, fallopian tubes, uterus, cervix, vagina, and vulva. Uterine and vaginal prolapse, cervical cancer, chorionic epithelial cancer, cervical erosion, cervical dysplasia, cervical cancer, vulvar vaginitis, vaginal mycosis, bacterial vaginitis, bartholinitis, vulva and vaginal cancer, sexually transmitted diseases (gonorrhea, chlamydia pelvic inflammatory disease, syphilis, trichomoniasis, Genital herpes, vulvar warts, genitals, etc., and these diseases are relatively common and most women have been reported to experience at least one disease over their lifetime.

The female genitourinary system contains a lactobacillus that maintains the pH of the genitourinary system at a weak acidity of 4.5 to 6.5, which prevents the growth of harmful bacteria. Or women's urogenital system-related diseases are likely to occur due to sexually transmitted diseases. In other words, the vagina and vulva are directly exposed to the external environment due to the functional characteristics of the female genitourinary system, and provide bacterial condition and bacterial vaginitis by providing a conditional environment in which various bacterial populations such as transfer, temperature, and humidity are cultured.

The primary function of the female genitourinary system is reproductive, so diseases affecting these organs can lead to infertility and can also degrade quality of life due to psychological problems such as depression.

In order to prevent such diseases of the genitourinary system of women, ancestors have treated vaginitis by sputum bathing by adding radish leaves or wormwood and cooling the boiled water, and Western women added water such as rose, lavender, and bergamot. However, this method has the disadvantage of being cumbersome to use every time.

In addition, existing soaps and body cleansers contain synthetic surfactants and have high pH and high cleansing effect.However, skin irritation and vaginal weak acidic pH environment is changed to alkaline environment. It may inhibit growth and provide an environment in which harmful bacteria can grow.

Therefore, it is an effective, hypoallergenic and easy-to-use female cleanser or vaginal cleaner for the prevention of diseases of the female genitourinary system, hypoallergenic compared to commonly used soaps and body cleansers, and contains natural ingredients as a functional and healthier environment. There is a need for the development of feminine cleaners that can provide high levels of care. In addition, in the case of general female cleansers, there is a disadvantage that is inconvenient to carry, and not easy to apply to a topical site, there is a need to improve the ease of portability and to facilitate application to a topical site.

The present invention has been made in view of the above object, and the object is to contain the fermentation composition powder in a capsule, to improve portability and to facilitate application to a topical site.

According to one embodiment of the invention, a) preparing a fermentation composition powder; b) selecting a capsule made of at least one polymer selected from the group consisting of chitooligosaccharide, gelatin, pectin, polyethylene glycol, methyl cellulose, sodium carboxymethyl cellulose, hydroxymethylpropyl cellulose and ethyl cellulose; And c) encapsulating the fermentation composition powder in a capsule.

In one embodiment of the present invention, the fermentation composition is Lactobacillus buchneri , Lactobacillus paracasei subsp. It may be naturally fermented by one or more strains selected from the group consisting of tolerans , Lactobacillus harbinensis , Saccharomycopsis fibuligera, and Pichia kudriavzevii .

In one embodiment of the present invention, there is provided a capsule female cleanser prepared according to the above method.

In one embodiment of the present invention, the capsule-type female detergent may further include one or more selected from natural material extracts selected from the group consisting of wormwood powder, allantoin, corn starch, tea tree oil and peppermint.

In one embodiment of the present invention, the capsule-type female cleansing agent may further include one or more additives selected from the group consisting of surfactants, moisturizers, conditioning agents, thickeners, neutralizers, pigments and flavorings.

In one embodiment of the present invention, the capsule-type female detergent may release the fermentation composition powder contained therein while the capsule is melted, or the capsule is broken.

According to the present invention, the capsule-type female detergent may be used in the form of being inserted into the local when used in a topical area which is a sensitive part of the woman, wherein the capsule slowly dissolves over time in the local, and thus fermentation in the capsule The composition powder is released, whereby it is slowly applied and absorbed in the topical area. Accordingly, it can be easily applied to the local part, there is a feature of less stimulation. In particular, the cleaner can effectively remove odors before and after menstruation, as well as help remove local secretions and treat inflammation.

1 is a photograph of a capsule-type female cleaner prepared according to an embodiment of the present invention.

Hereinafter, the present invention will be described in more detail.

Specifically, the method for producing a capsule-type female detergent according to an embodiment of the present invention comprises the steps of a) preparing a fermentation composition powder; b) selecting a capsule made of at least one polymer selected from the group consisting of chitooligosaccharide, gelatin, pectin, polyethylene glycol, methyl cellulose, sodium carboxymethyl cellulose, hydroxymethylpropyl cellulose and ethyl cellulose; And c) encapsulating the fermentation composition powder in a capsule.

First, the fermentation composition powder is prepared (step a).

According to one embodiment of the present invention, the fermentation composition may be in powder form and may be a material that can be used as a female detergent.

Specifically, according to one embodiment of the present invention, the fermentation composition powder is Lactobacillus buchneri , Lactobacillus paracasei subsp. Tolerans , Lactobacillus harbinensis , Saccharomycopsis fibuligera and Pichia kudriavzevii may be prepared by inoculating one or more strains selected from the group consisting of natural fermentation.

The rice bran refers to a pulverized mixture such as skin, seedling, whistle layer, etc. generated during the milling of rice. In the present invention, the method of milling to obtain the rice bran is not particularly limited, and may be, for example, obtained by using a vertical grinding or friction type mill.

According to one embodiment of the present invention, the extraction process of obtaining the rice bran extract from the rice bran may be performed by extracting for 24 to 48 hours at a temperature of 40 to 100 ℃, specifically 80 to 100 ℃ using a solvent. .

Specifically, the solvent in the extraction process may be using distilled water, 1 to 5 parts by weight of the mixture is added to distilled water based on 100 parts by weight of distilled water, and then for 24 to 48 hours at a temperature of 80 to 100 ℃, in detail 36 Extraction can be performed using a reflux condenser for hours.

On the other hand, the mixed extract obtained through the above process may be stored in the refrigerator through a process of cooling for about 3 hours at room temperature (about 25 ℃). On the other hand, the mixed extract may be further subjected to sterilization for 10 to 20 minutes at 115 to 130 ℃ temperature prior to the fermentation process to be described later, in detail, the sterilization process may be performed at 120 ℃ 15 minutes. Through the sterilization process to kill the bacteria in the extract.

Next, Lactobacillus buchneri and Lactobacillus paracasei subsp. Tolerans , Lactobacillus harbinensis , Saccharomycopsis fibuligera and Pichia kudriavzevii can be inoculated with one or more strains selected from the group consisting of natural fermentation to prepare a fermentation composition.

Strains used in one embodiment of the present invention are specifically Lactobacillus buchneri , Lactobacillus paracasei subsp. Tolerans , Lactobacillus harbinensis , Saccharomycopsis fibuligera and Pichia kudriavzevii may be one or more strains selected from the group consisting of. Fermentation of rice bran extract using the above-described strains will add antioxidant, anti-inflammatory and whitening effects to the fermentation composition produced. Thus, the fermentation composition is suitable for feminine cleaner use.

Specifically, the strain may be used incubated for about 48 hours at 37 ℃ temperature conditions in YM medium to MRS medium, may be cultured by stirring at 180 rpm, for example.

On the other hand, according to an embodiment of the present invention, the strain may be 0.20 to 1.5 parts by weight based on 100 parts by weight of the rice bran extract. When the strain is in the above weight part range, the number of bacteria in the strain is an optimal amount to perform the above natural fermentation process.

On the other hand, as the rice bran extract is naturally fermented by the above-mentioned strain, rice bran fermentation composition is obtained. On the other hand, the fermentation process, specifically, the natural fermentation process may be performed for 24 to 72 hours at 30 to 38 ℃ temperature, specifically may be performed for 48 hours at 37 ℃ temperature.

Meanwhile, after the step, the supernatant of the rice bran fermentation composition may be separated, and the process of filtration and sterilization of the supernatant may be further performed.

Specifically, the residue may be removed through the supernatant separation process, and the obtained supernatant is removed again due to the filtration process, and thus impurities are not included. Through the above process, the rice bran fermentation composition from which impurities are completely removed may be further subjected to sterilization at a temperature of 115 to 130 ° C.

The rice bran fermentation composition obtained according to the above method is subjected to a powdering step, wherein the powdering step may be performed by a method such as hot air drying, and the fermentation composition powder is prepared through the series of processes.

Next, a capsule made of at least one polymer selected from the group consisting of chitooligosaccharide, gelatin, pectin, polyethylene glycol, methyl cellulose, sodium carboxymethyl cellulose, hydroxymethylpropyl cellulose and ethyl cellulose is selected (step b). .

The capsule may be made of one or more polymers selected from the group consisting of chitooligosaccharide, gelatin, pectin, polyethylene glycol, methyl cellulose, sodium carboxymethyl cellulose, hydroxymethyl propyl cellulose and ethyl cellulose, and the general It may be prepared according to the method. On the other hand, the capsule should be a material harmless to the human body.

Next, the fermentation composition powder is encapsulated (step c).

In the case of the step is a process of containing the fermentation composition powder in the capsule, the capsule size can be variously selected according to the shape, size and purpose of the capsule, for example, 100 to 1000mg of the fermentation composition in a capsule container by using a capsule charger It can be contained in the form of filling the powder.

According to another embodiment of the present invention, there is provided a capsule female cleanser prepared according to the above method.

On the other hand, according to one embodiment of the present invention, in order to give additional functionality to the capsule-type female detergent, 1 selected from the extract of natural ingredients selected from the group consisting of wormwood powder, allantoin, corn starch, tea tree oil and peppermint It may be to include more than one species. On the other hand, the capsule female cleansing agent may have one or more effects selected from anti-inflammatory, antioxidant, and whitening.

Meanwhile, the capsule-type female cleanser may further include one or more additives selected from the group consisting of surfactants, moisturizers, conditioning agents, thickeners, neutralizers, pigments, and flavors. On the other hand, the additives may be used in the general ones used in the art.

As described above, the capsule-type female cleanser has a form in which the powder is supported in the capsule, so that it is easy to carry, and in use, it can be used in the form of inserting the capsule into the female local site, so that it is easy to apply to the topical site. Specifically, as the capsule melts over time in the female part, or the capsule is destroyed, the capsule releases the fermentation composition powder contained in the capsule, so that the fermentation composition powder is slowly applied and applied in the local part. Is absorbed, and thus the female cleanser efficacy can be sustained for a long time.

As the invention allows for various changes and numerous modifications, particular embodiments will be illustrated and described in detail below. However, this is not intended to limit the present invention to the specific disclosed form, it should be understood to include all modifications, equivalents, and substitutes included in the spirit and scope of the present invention.

Example 1: Fermentation Composition Powder Preparation

Mix 100 g of rice bran into a 2 L round bottom flask. 1L of distilled water was put into this flask, and it refluxed at 100 degreeC for 36 hours. After extraction, the extract was cooled to room temperature and sterilized in a sterilizer (121 ° C., 20 minutes). The sterilized extract was cooled for 2 hours and then sealed and refrigerated to obtain rice bran extract.

And then were inoculated into into the rice bran extract a 2L Erlenmeyer flask, a mixture of the cultured strain (Lactobacillus buchneri, Lactobacillus paracasei subsp. Tolerans, Lactobacillus harbinensis, Saccharomycopsis fibuligera and Pichia kudriavzevii) such that the weight ratio of 1g based on the rice bran extract 100g . After inoculation, the mixture was put in a stirring incubator at 37 ° C. for 48 hours. After the fermentation was completed, the resultant was centrifuged to remove the fermentation debris and the supernatant was taken. The aliquot of the supernatant was removed by vacuum filtration using diatomaceous earth. After the filtration was sterilized in a sterilizer (121 ℃, 20 minutes). The sterilized fermentation composition was sealed and refrigerated to obtain a fermentation composition. 500 ml of the fermentation composition obtained through the above process was placed in a 2L beaker, 250 g of corn starch was added, and stirred and mixed using a stirrer. When the mixture was sufficiently mixed, the mixture was spread in a drying container and hot-air dried at 70 ° C. for 24 hours. After drying, the particles were homogenized using a grinder and sealed to obtain 240 g of the title powder.

Next, 700 mg of the powder was put in a capsule container made of gelatin using a capsule charger, thereby obtaining a capsule-type female cleaner.

Experimental Example 1. Application of affected area

After applying the capsule-type female detergent to the affected area twice a week for one week in the morning and evening for 40 women, the odor, mask irritation and secretion improvement were investigated to investigate whether or not masking odor and irritation. As a result, 32 people said they didn't smell bad and 8 people said they don't know bad. In addition, 30 respondents said they had an effect on improving secretions, and 10 respondents said they did not know. In addition, lesion irritation did not feel all 40 people. Therefore, it can be seen that the capsule-type female cleansing agent according to the present invention is effective in removing odor and improving secretion, and it is confirmed that there is no irritation of the affected area.

Claims (6)

a) extract rice bran extract from Lactobacillus buchneri, Lactobacillus paracasei subsp. preparing a fermented composition powder naturally fermented with one or more strains selected from the group consisting of tolerans, Lactobacillus harbinensis, Saccharomycopsis fibuligera, and Pichia kudriavzevii;
b) preparing a natural material extract consisting of corn starch;
c) selecting a capsule made of at least one polymer selected from the group consisting of chitooligosaccharide, gelatin, pectin, polyethylene glycol, methyl cellulose, sodium carboxymethyl cellulose, hydroxymethyl propyl cellulose and ethyl cellulose; And
d) encapsulating the fermentation composition powder in a capsule. delete A capsule female cleanser prepared according to the method of claim 1. delete The method of claim 3, wherein
The capsule female cleansing agent further comprises one or more additives selected from the group consisting of surfactants, moisturizing agents, conditioning agents, thickeners, neutralizers, pigments and flavorings. The method of claim 3, wherein
The capsule female detergent is a capsule female detergent to release the fermentation composition powder contained therein while the capsule is melted, the capsule is broken.

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