KR102004212B1 - Manufacturing method for a better absorbing hydro colloid based hotmelt dressing tape - Google Patents

Abstract

The present invention relates to a hydro-colloid hotmelt wettable dressing tape having improved absorption force. According to the present invention, the hydro-colloid hotmelt wettable dressing tape comprises a base film (110) and a dressing agent (120) formed on an upper surface of the base film (110) and includes a hot melt adhesive agent, a hydro-colloid, and a moisture absorbent for absorbing exudates of wounds. According to the same, it is possible to quickly absorb a large amount of exudates and also the moisture absorbent can continue to act for a long time.

Description

TECHNICAL FIELD [0001] The present invention relates to a hydrocolloid hot melt wetting dressing tape,

The present invention relates to a wettable dressing tape, and more particularly, to a method for manufacturing a hydro-colloid hot-melt wettable dressing tape having an improved absorption capacity which makes it possible to rapidly and simultaneously absorb a large amount of exudates and to allow a moisture absorber to be continuously operated for a long time .

In recent years, there has been a need for a wettable dressing band or a wettable dressing which can treat people so that their interest in cosmetics increases and the wounds keep moist as the beauty industry grows.

There are two types of wetting dressing bands: a foam-type dressing band made of the same material as a sponge, and a dressing band made of a rubber-like hard-colloid type.

The foam-type wetting dressing band is thicker and has better absorbing ability to absorb the material and has the advantage of protecting the wound area from the impact, which is more effective for scarring and scarring.

However, there was an inconvenience that it was necessary to use a separate attachment foil because there was no adhesive force.

The hydro-colloidal type dressing band is thin, so it has excellent adhesion, but absorption power is weaker than foam type and it is mainly used for light scratches such as scratches.

When a wound occurs in the skin, the exudate of the wound surface is dried to form a crust, and the lower part of the wound beneath the crust is dry-necrotic due to a high moisture permeability. Finding and walking along the path of necrotic skin.

In this case, when the wound portion is maintained in the dry state, the movement of the regenerated epithelial cells is unnatural and abnormal, and the speed is slower than when the wound is maintained in the wet state.

In addition, due to the adherence between gauze and regenerated tissue or crust, the exchange of gauze causes damage to the new tissue, causing pain to the patient, delaying wound healing, and causing scarring.

Therefore, in order to minimize scarring and safe treatment, there is a need to develop hydro-gel polymer materials for wet environment dressing, and development of better related products is required.

Document 1: Published Patent Application No. 10-2004-0053184 (Publication date: June 23, 2004) Document 2: Published Patent Application No. 10-2010-0039532 (Publication Date: Apr. 16, 2010)

The present invention has been made to solve the above-mentioned problems of the prior art, and it is an object of the present invention to provide a hydrocolloid hot melt wetting dressing tape having improved absorption power,

First, since the hygroscopic agent is mixed and contained with the hydro-colloid, the exudates can be rapidly and simultaneously absorbed in a large amount, and the hygroscopic agent can be continuously operated for a long time,

Secondly, by mixing the hydrocolloid and the moisture absorbent in the molten state of the hot-melt adhesive, mixing of the hydrocolloid and the hygroscopic agent becomes possible,

Third, the hydrocolloid and the hygroscopic agent can be stably mixed by setting the temperature at which the hydrocolloid is introduced into the hot-melt adhesive and the temperature at which the hygroscopic agent is introduced,

Fourth, by mixing the hydrocolloid with the antibacterial and antiviral substances, the wound can be treated more quickly in a state where the wettability is maintained,

Fifthly, by providing the base film with an ultraviolet screening agent, it is possible to directly block the ultraviolet rays directly from the base film layer serving as a cover film exposed to the outside, thereby protecting the wounds more securely from ultraviolet rays In addition,

Sixth, mixing of the ultraviolet screening agent into the thermoplastic polyurethane resin in a dissolved state at a high temperature makes it easier to mix,

Seventhly, it is an object of the present invention to provide a method for producing a hydro-colloid hot-melt wettable dressing tape having an improved water absorption capacity suitable for providing a base film with a waterproof function.

In order to attain the above object, the present invention provides a hydrocolloid hot-melt wetting dressing tape having improved absorbency, comprising: a substrate film; a moisture-absorbing agent for absorbing exudates of a hot-melt adhesive, a hydrocolloid, And a dressing agent which is constituted by including a dressing agent.

The hydro-colloid hot-melt wettable dressing tape of the present invention has the above-mentioned hydro-colloid hot-melt wettable dressing tape, in which the dressing agent is put into a heating stirrer and heated and melted, then the hydro-colloid is stirred at a first set temperature, Mixing the colloid with the moisture absorbent at a second set temperature in a mixed and stirred state, mixing and stirring the mixture, and then coating the same on one surface of the base film.

The hydro-colloid hot-melt wetting dressing tape of the present invention is characterized in that the dressing agent is 20 to 40 parts by weight of hydro-colloid and 1 to 5 parts by weight of a hygroscopic agent with respect to 100 parts by weight of the hot-melt adhesive.

The hydro-colloid hot-melt wetting dressing tape of the present invention having an improved absorption capacity is characterized in that the hydro-colloid is selected from the group consisting of Carboxymethylcellulose Sodium, Hydroxyethylcellulose, Ethylcellulose, And is at least one selected from the group consisting of hydroxypropylcellulose, methylcellulose, polyether, hydroxypropylmethylcellulose, and Carmellose sodium

The hydrocolloid hot melt wettable dressing tape according to the present invention is characterized in that the moisture absorbent is a polyacrylamide, a polyether oxide, a polyethylene oxide, a polyethylene glycol, a polyethyleneglycol- At least one selected from the group consisting of polypropyleneglycol copolymer, beta-glucan, polyvinyl alcohol, polyvinyl pyrrolidone, K-carrageenan, glycerol, .

The hydro-colloid hot-melt wettable dressing tape of the present invention having improved absorption capacity is characterized in that the dressing agent further comprises antibacterial and antiviral substances.

The hydro-colloid hot-melt wetting dressing tape according to the present invention is characterized in that the dressing agent is put into a heating stirrer and heated and melted, then the hydro-colloid is added and stirred at a first set temperature, A colloid is mixed and agitated, a moisture absorbent, an antibacterial and an antiviral substance are added at a second set temperature, mixed and stirred, and then coated on one side of the base film by a coater.

The hydrocolloid hot melt wettable dressing tape of the present invention is characterized in that the antibacterial and antiviral substance is selected from the group consisting of Silver sulfadiazine, Chloramphenicol, Tetracycline, Chlortetracycline, It can be used in combination with oxytetracycline, Sulfonamides Silver, Sulfadiazine, Sulfathiazole, Mafenide, Sulfamethizole, Sulfanilamide, And is at least one selected from the group consisting of Sulamerazine beta-sitosterol, AgF ₂ , Ag ₂ O ₃ , AgF ₃ , Ag ₂ S ₃ , Ag ₄ O ₄ , AgHSO ₄ and Ag ₂ SeO ₃ .

The hydro-colloid hot-melt wettable dressing tape of the present invention having improved absorption ability is characterized by being 0.5 to 1.5 parts by weight of the antibacterial and antiviral material per 100 parts by weight of the hydro-colloid.

The hydrocolloid hot-melt wettable dressing tape of the present invention having improved absorption ability is characterized in that the base film is composed of a thermoplastic polyurethane resin and an ultraviolet screening agent.

The hydrocolloid hot melt wettable dressing tape of the present invention is characterized in that the thermoplastic polyurethane resin and the ultraviolet screening agent are 0.3 to 0.5 parts by weight of an ultraviolet screening agent per 100 parts by weight of the thermoplastic polyurethane resin.

The hydrocolloid hot melt wettable dressing tape of the present invention having an improved absorption capacity is characterized in that the base film comprises a step of injecting a thermoplastic polyurethane resin into a heating stirrer to melt the thermoplastic polyurethane resin while heating the thermoplastic polyurethane resin and heating the thermoplastic polyurethane resin in a molten state, Adding the ultraviolet ray blocking agent to the resin, mixing the mixture with stirring, and molding the thermoplastic polyurethane resin mixed with the ultraviolet screening agent into a film shape.

The hydro-colloid hot-melt wetting dressing tape of the present invention having improved absorption ability is characterized in that the ultraviolet screening agent is composed of at least one selected from arbutin, zinc oxide, and titanium oxide.

The hydro-colloid hot-melt wettable dressing tape of the present invention having an improved absorption capacity is characterized in that a waterproof film is attached to the dressing.

The hydro-colloid hot-melt wettable dressing tape having the above-described structure of the present invention having the improved absorption capacity has the following effects.

First, since the hygroscopic agent is mixed and contained with the hydro-colloid, the exudates can be rapidly and simultaneously absorbed in a large amount, and the hygroscopic agent can be continuously applied for a long time.

Secondly, there is an effect that the hydrocolloid and the moisture absorber can be mixed in the state that the hot-melt adhesive is melted, whereby the hydrocolloid and the hygroscopic agent can be mixed.

Third, since the exudate can be absorbed by the absorbent, it shortens the healing time of the wound and does not cause scarring, so there is no pain when removing it. In addition, it has the effect of blocking bacteria and preventing scar formation by preventing the formation of scab, which is the cause of scarring.

Fourth, there is an effect that the hydrocolloid and the hygroscopic agent can be stably mixed by setting the temperature for introducing the hydrocolloid and the temperature for introducing the hygroscopic agent differently in the hot-melt adhesive.

Fifth, by mixing hydrocolloid with antibacterial and antiviral substances, it is possible to safely treat wounds more rapidly in a state where wettability is maintained.

Sixth, the ultraviolet ray blocking agent is contained in the base film, so that the ultraviolet ray can be directly blocked from the base film layer serving as a cover film exposed to the outside. As a result, the wound is more reliably protected from ultraviolet rays There is an effect that can be done.

Seventh, mixing of the ultraviolet screening agent into the thermoplastic polyurethane resin in a dissolved state at a high temperature can be further facilitated.

Eighth, there is an effect that the base film can be provided with a waterproof function.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a configuration diagram of a hydrocolloid hot melt wettable dressing tape with improved absorption power according to an embodiment of the present invention; FIG.
FIG. 2 is a process diagram for producing a substrate film 110 in a hydrocolloid hot-melt wettable dressing tape with improved absorption capacity according to an embodiment of the present invention.
FIG. 3 is a process diagram for manufacturing a dressing agent 120 in a hydrocolloid hot-melt wettable dressing tape having improved water absorption according to an embodiment of the present invention.

A preferred embodiment of the hydro-colloid hot-melt wettable dressing tape of the present invention is described in detail below with reference to the accompanying drawings.

As shown in the figure, the hydrocolloid hot-melt wetting dressing tape 100 having improved absorption capacity according to an embodiment of the present invention includes a base film 110 serving as a cover film, And a dressing agent (120) formed thereon.

The dressing agent 120 includes a hot-melt adhesive, a hydro-colloid, and a moisture absorbent for absorbing exudates generated from a wound.

Since the hygroscopic agent is mixed and contained together with the hydro-colloid as described above, the exudate can be rapidly and simultaneously absorbed in a large amount, and the hygroscopic agent can be continuously operated for a long time. That is, the hygroscopic agent and the hydro-colloid can complement each other to improve the absorption time and the absorption amount.

In the hydrocolloid hot-melt wetting dressing tape 100 according to the embodiment of the present invention, the dressing agent 120 is heated and melted (S31) after the hot- , The hydrocolloid is added and stirred at a first set temperature (150 DEG C) (S32), the hygroscopic agent is added at a second set temperature (135 to 140 DEG C) while the hydrocolloid is mixed and stirred, (S33), for example, by an adhesive coating (S34) on one surface of the base film 110 by a coating mechanism (not shown).

As described above, since the hydrocolloid and the hygroscopic agent are put in the melted state of the hot-melt adhesive, mixing of the hydrocolloid and the hygroscopic agent becomes possible.

In addition, there is an advantage that the moisture-absorbing agent can be stably mixed by putting the moisture-absorbing agent in a different temperature state of the hot-melt adhesive and the hydro-colloid.

In the hydrocolloid hot-melt wetting dressing tape 100 according to an embodiment of the present invention, the dressing agent 120 may include 20-40 parts by weight of hydrocolloid, 100 parts by weight of a hygroscopic agent 5 to 15 parts by weight.

According to such a mixed composition ratio, there is an advantage that the absorbency of the exudate (soul) is 1.5 times that of the conventional product.

The hydrocolloid may be selected from the group consisting of Carboxymethylcellulose Sodium, Hydroxyethylcellulose, Ethylcellulose, Hydroxypropylcellulose, Methylcellulose, And one or more selected from the group consisting of polyether, hydroxypropylmethylcellulose, and Carmellose sodium.

The moisture absorbent may be selected from the group consisting of Polyacrylamide, Polyiodide, Polyethyleneoxide, Polyethyleneglycol, PEG-PPG (Polyethyleneglycol-Polypropyleneglycol) copolymer, Beta Glucan, And at least one or more selected from the group consisting of polyvinyl alcohol, polyvinyl pyrrolidone, K-carrageenan, and glycerol.

In the hydrocolloid hot melt wettable dressing tape 100 according to another embodiment of the present invention, the dressing agent 120 may include one or more antibacterial and antiviral substances. do.

As described above, by mixing the hydrocolloid with the antibacterial and antiviral substances, there is an advantage that the wound can be treated more rapidly in a state where the wettability is maintained.

Particularly, since the antibacterial and antiviral substances are mixed with the hydro-colloid, the secondary infection can be further prevented.

In the hydrocolloid hot-melt wetting dressing tape 100 according to another embodiment of the present invention, the dressing agent 120 is heated and melted (S31) after a hot- Colloid is mixed and stirred at a first set temperature (150 DEG C) (S32), and the hygroscopic agent and the antibacterial and antiviral substance are mixed at a second set temperature (135 to 140 DEG C) (S33), and is then formed by an adhesive coating (S34) on one side of the base film 110 with a coating mechanism (not shown).

The antimicrobial and antiviral substance may be selected from the group consisting of Silver sulfadiazine, Chloramphenicol, Tetracycline, Chlortetracycline, Oxytetracycline, Sulfonamides Silver, Sulfadiazine, Sulfathiazole, Mafenide, Sulfamethizole, Sulfanilamide, Sulamerazine beta-sitosterol, AgF ₂ , Ag ₂ O ₃ , AgF ₃ , Ag ₂ S ₃ , Ag ₄ O ₄ , AgHSO ₄ , and Ag ₂ SeO ₃ .

The composition of the hydrocolloid and the antibacterial and antiviral material is 0.5 to 1.5 parts by weight of the antibacterial and antiviral material per 100 parts by weight of the hydrocolloid.

Such a mixed composition ratio has an advantage that the effect of antibacterial and antiviral is further increased.

In the hydro-colloid hot-melt wetting dressing tape 100 according to another embodiment of the present invention, the dressing agent 120 is provided with a waterproof film 130 having a waterproof function.

According to this, since the dressing tape itself has a waterproof function, it can be used smoothly even in the case of swimming, bathing or rainy weather.

Next, the construction and operation of the hydrocolloid hot-melt wetting dressing tape 100 with improved absorption capacity according to still another embodiment of the present invention will be described.

In the hydrocolloid hot melt wetting dressing tape 100 according to another embodiment of the present invention, the base film 110 is formed of a thermoplastic polyurethane resin and an ultraviolet screening agent .

As described above, since the base film 110 contains the ultraviolet screening agent, ultraviolet rays can be blocked in units of the base film 110, and thus the wound can be more reliably protected from ultraviolet rays.

In particular, when the hydrocolloid hot-melt wetting dressing tape 100 according to another embodiment of the present invention is adhered to the skin, the base film 110 may be coated with a dressing material 120 and a cover film It is possible to more surely protect the scars of the skin and to provide more protection because the base film 110 contains the ultraviolet screening agent.

The composition ratio of the thermoplastic polyurethane resin to the ultraviolet screening agent is 0.1 to 1.0 part by weight of the ultraviolet screening agent per 100 parts by weight of the thermoplastic polyurethane resin. According to this composition ratio, there is an advantage of enhancing the ultraviolet blocking effect.

The base film 110 is prepared by preparing a thermoplastic polyurethane resin and an ultraviolet screening agent (for example, a powder state), introducing the thermoplastic polyurethane resin into a heating stirrer to melt the thermoplastic polyurethane resin while heating (S21) (S22) of injecting an ultraviolet screening agent into the thermoplastic polyurethane resin in a molten state and stirring the mixture, and molding the thermoplastic polyurethane resin mixed with the ultraviolet screening agent into a film form (S23) .

As described above, there is an advantage that the ultraviolet screening agent can be easily mixed with the thermoplastic polyurethane resin by adding the ultraviolet screening agent to the thermoplastic polyurethane resin in a high temperature and dissolved state and stirring and mixing. In addition, there is a safety advantage because it has a waterproof function that can prevent moisture from the outside, antibacterial and antiviral function.

The ultraviolet screening agent is characterized in that it is composed of one or a plurality of mixtures selected from arbutin, zinc oxide, and titanium oxide.

Hereinafter, a method of manufacturing a hydro-colloid hot-melt wettable dressing tape having an improved absorption capacity according to an embodiment of the present invention will be described.

First, the process of manufacturing the dressing agent 120 will be described.

The hot-melt adhesive is placed in a heating stirrer and heated to melt (S31).

When the hot-melt adhesive in the melted state reaches 150 캜, for example, the hydro-colloid is added and stirred (S32). The stirring time is, for example, 2 to 3 hours.

The hot-melt adhesive and the hydro-colloid are melted and mixed and stirred. The temperature is lowered to 135 to 140 ° C. The moisture absorbent, the antibacterial and antiviral material are added at this lower temperature, and the mixture is stirred and mixed (S33). The stirring time is, for example, 2 to 3 hours.

The hot-melt adhesive mixed with the hygroscopic agent, the antibacterial agent, and the antiviral agent and the solution in which the hydro-colloid is melted are coated on the one surface of the base film 110 by a coating mechanism (not shown) (120) is completed.

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Next, a method of producing the base film 110 containing an ultraviolet screening agent will be described.

A thermoplastic polyurethane resin and an ultraviolet screening agent (for example, a blocker in a fine powder state, that is, a so-called powder state blocking agent) are prepared.

The thermoplastic polyurethane resin is put into a heating stirrer to melt the thermoplastic polyurethane resin while heating (S21).

When the dissolved thermoplastic polyurethane resin reaches room temperature, an ultraviolet screening agent is added and mixed by stirring (S22).

Add sunscreen and stir for 3 ~ 6hrs.

A thermoplastic polyurethane resin mixed with an ultraviolet screening agent is formed into a film form (S23).

As a method for molding into a film shape, it can be formed, for example, by coating the release paper using a coating mechanism.

[Test Example 1] - Absorption rate test

 In the conventional product (blank sample), a weight ratio of 35% of carboxymethylcellulose sodium as a hydrocolloid was adopted for 100% (hereinafter, all the weight%) of the hot-melt adhesive.

The hot-melt adhesive and hydrocolloid used in Samples 1 to 4 of Test Example 1 were the same as those of the conventional product (comparative sample), and the same weight ratios as those of the conventional product were tested by adding the following desiccants. Weight ratio, and the test solution is 90% of distilled water + 10% of PBS (Phosphate buffered saline).

Sample 1 (F3): PEG-PPG (Polyethylene Glycol-Polypropylene Glycol), 3%

Sample 2 (P6): EG polymer (Polyethylene Glycol), 2%

Sample 3 (P6N): PEG-PPG copolymer (0.2%) + EG polymer (2%)

Sample 4 (P6N1): PEG-PPG copolymer (0.1%) + EG polymer (4%)

[Table 1] Absorption rate test result

[Picture of sample after 48 hours]

Conventional product (Blank)

Sample 1 (F3)

Sample 2 (P6), Sample 3 (P6N), Sample 4 (P6N1)

[graph]

The absorption rate increased 5-fold after 2 hours of addition of the PEG-PPG copolymer (1 to 3%) and the EG polymer (2%) compared to the blank sample (ratio of the existing hydrocolloid 35% ) And PEG-PPG copolymer (0.2%) were added [Sample 3 (P6N)], which was about 14 times higher than that of sample 3 (P6N).

In order to further improve the water uptake, the amount of the EG polymer was doubled, and the sample with the PEG-PPG copolymer reduced by 50% was prepared and subjected to the water absorption test [Sample 4 (P6N1)], Respectively.

[Test Example 2] - Ultraviolet blocking rate test

Carboxymethylcellulose sodium was used as a hydrocolloid and zinc oxide (ZnO) and titanium oxide (TiO ₂ ) as an ultraviolet screening agent were used to test the ultraviolet barrier and ultraviolet barrier index , The results are as follows.

The sample # 1 and the sample # 2 (# 2-1, # 2-2) were obtained by simply mixing the base film 110 with the ultraviolet screening agent and not coating the hydrocolloid with the hot-melt adhesive.

Samples # 3 and # 4 were coated with hydrocolloid and hot melt adhesive.

In the above data, it can be seen that samples # 3 and # 4 have a very high blocking rate, a very low transmittance and an excellent UPF (ultraviolet protection factor). This is because, It can be confirmed that the use of the hydro-colloid and the hot-melt adhesive together has higher cut-off rate and lower transmittance.

It can be seen that the ultraviolet screening agent is mixed with the base film and at the same time, the ultraviolet ray blocking rate is high and the transmittance is low due to the complementary action of the dressing agent.

It will be apparent to those skilled in the art that the present invention may be embodied in other specific forms without departing from the spirit or scope of the invention as defined in the appended claims. It is self-evident to those who have.

Therefore, the above-described embodiments are to be considered as illustrative rather than restrictive, and accordingly the present invention is not limited to the above description, but may be modified within the scope of the appended claims and equivalents thereof.

100: Hydrocolloid hot-melt wetting dressing tape with improved absorption capacity according to an embodiment of the present invention
110: base film
120: Dressing agent
130: Waterproof film

Claims (4)

The hot-melt pressure-sensitive adhesive is put into a heating stirrer to be heated and melted (S31)
The hydro-colloid is added to the hot-melt adhesive in a molten state at a first set temperature and stirred (S32)
The hygroscopic agent and the antimicrobial and antiviral substance for absorbing the exudates of the wound are added at a second set temperature while the hot-melt adhesive and the hydro-colloid are melted and mixed and stirred (S33)
The hot-melt adhesive mixed with the hygroscopic agent, the antibacterial agent and the antiviral agent and the solution in which the hydro-colloid is melted are coated on the upper surface of the base film 110 serving as a cover film by a coating mechanism (S34) (120) is formed on the upper surface of the base film (110)
The moisture-
Polyacrylamide, polyimide, polyethylene oxide, polyethyleneglycol, PEG-PPG (polyethyleneglycol-polypropyleneglycol) copolymer, beta-glucan, polyvinyl alcohol alcohol, at least one selected from polyvinyl pyrrolidone, K-carrageenan, and glycerol,
The composition of the hydrocolloid and the antibacterial and antiviral material is 0.5 to 1.5 parts by weight of the antibacterial and antiviral material per 100 parts by weight of the hydrocolloid. Way.
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