KR101993124B1 - Novel Salmonella specific bacteriophage SG1 and antibacterial composition comprising the same - Google Patents

Novel Salmonella specific bacteriophage SG1 and antibacterial composition comprising the same Download PDF

Info

Publication number
KR101993124B1
KR101993124B1 KR1020170170714A KR20170170714A KR101993124B1 KR 101993124 B1 KR101993124 B1 KR 101993124B1 KR 1020170170714 A KR1020170170714 A KR 1020170170714A KR 20170170714 A KR20170170714 A KR 20170170714A KR 101993124 B1 KR101993124 B1 KR 101993124B1
Authority
KR
South Korea
Prior art keywords
salmonella
bacteriophage
present
composition
feed
Prior art date
Application number
KR1020170170714A
Other languages
Korean (ko)
Other versions
KR20180074581A (en
Inventor
김영주
연영은
한범구
김현일
박철세
Original Assignee
주식회사 옵티팜
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 옵티팜 filed Critical 주식회사 옵티팜
Publication of KR20180074581A publication Critical patent/KR20180074581A/en
Application granted granted Critical
Publication of KR101993124B1 publication Critical patent/KR101993124B1/en

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A23L3/3571—Microorganisms; Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/381—Microorganisms
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/00031—Uses of virus other than therapeutic or vaccine, e.g. disinfectant
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/00032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Dentistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Mycology (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)

Abstract

본 발명은 살모넬라균, 특히 살모넬라 갈리나륨, 살모넬라 플로럼 및 살모넬라 콜레라수이스에 특이적인 사멸능을 갖는 신규 박테리오파지 SG1, 상기 박테리오파지를 포함하는 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제 또는 세척제 및 상기 박테리오파지를 개체에 투여하는 단계를 포함하는 살모넬라균에 의한 감염성 질병의 예방 또는 치료 방법에 관한 것이다. 본 발명의 박테리오파지 SG1을 이용한 살모넬라균에 의한 감염성 질병의 예방 또는 치료 방법은 기존의 항생제 등의 화학물질에 비해 살모넬라균에 대한 특이성이 매우 높고, 상기 박테리오파지 SG1은 살모넬라균에 감염하여 살모넬라균 내에서 증식함으로써 용균 활성이 우수하고 물리화학적 자극에 강하다는 장점을 가지고 있다. 또한 본 발명의 박테리오파지 SG1은 사람, 동물, 식물 등 세균 외의 다른 숙주에는 감염되지 않으므로, 항생제의 오남용으로 인한 항생제 내성균의 문제점, 식품 내의 항생제의 잔류 문제, 광범위한 숙주범위의 문제점을 해결할 수 있는 장점이 있다. 따라서, 본 발명의 박테리오파지 SG1은 다양한 살모넬라균에 의한 감염성 질병의 예방 또는 치료, 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제, 또는 세척제 분야에서 다양하게 사용될 수 있다.The present invention relates to a novel bacteriophage SG1 having saliva specific to Salmonella, particularly Salmonella Galiumarium, Salmonella Florum and Salmonella cholera strain, an antibiotic composition comprising the bacteriophage, a composition for feed addition, a feed, a disinfectant or a cleansing agent And a method for preventing or treating an infectious disease caused by Salmonella comprising the step of administering the bacteriophage to an individual. The method for preventing or treating infectious diseases caused by Salmonella using the bacteriophage SG1 of the present invention is highly specific to Salmonella than the chemical substances such as existing antibiotics, and the bacteriophage SG1 is infected with Salmonella, It has an advantage that it is excellent in lytic activity and strong against physicochemical stimulation by proliferation. In addition, since the bacteriophage SG1 of the present invention is not infected by any host other than bacteria such as humans, animals and plants, it can solve problems of antibiotic resistant bacteria caused by abuse of antibiotics, residual antibiotics in food, have. Accordingly, the bacteriophage SG1 of the present invention can be used in various fields in the field of preventing or treating infectious diseases caused by various Salmonella, antibiotic composition, composition for feed addition, feed, disinfectant, or detergent.

Description

신규한 살모넬라균 특이 박테리오파지 SG1 및 이를 포함하는 항균 조성물{Novel Salmonella specific bacteriophage SG1 and antibacterial composition comprising the same}A novel salmonella-specific bacteriophage SG1 and an antimicrobial composition comprising the Salmonella specific bacteriophage SG1 and antibacterial composition,

본 발명은 살모넬라균, 특히 살모넬라 갈리나륨, 살모넬라 플로럼 및 살모넬라 콜레라수이스에 특이적인 사멸능을 갖는 신규 박테리오파지 SG1, 상기 박테리오파지를 포함하는 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제 또는 세척제 및 상기 박테리오파지를 개체에 투여하는 단계를 포함하는 살모넬라균에 의한 감염성 질병의 예방 또는 치료 방법에 관한 것이다. The present invention relates to a novel bacteriophage SG1 having saliva specific to Salmonella, particularly Salmonella Galiumarium, Salmonella Florum and Salmonella cholera strain, an antibiotic composition comprising the bacteriophage, a composition for feed addition, a feed, a disinfectant or a cleansing agent And a method for preventing or treating an infectious disease caused by Salmonella comprising the step of administering the bacteriophage to an individual.

살모넬라(Salmonella)는 장내세균과에 속하는 그람음성의 통성혐기성 세균으로, 아포를 형성하지 않는 간균이다. 살모넬라균은 사람뿐만 아니라 돼지, 소, 닭 등을 비롯한 다양한 가축에 감염되어 질병을 유발하는데, 사람에게 감염되어 식중독을 유발하고 동물에게 있어서는 다양한 살모넬라증(Salmonellosis)을 유발하는 병원성 미생물이다. 살모넬라 엔테리카(Salmonella enterica)는 혈청학적 구분에 의해 장티푸스를 일으키는 살모넬라 타이피(Salmonella Typhi), 쥐티푸스의 원인균인 살모넬라 티피뮤리움(Salmonella Typhimurium), 장염균인 살모넬라 엔테리티디스(Salmonella Enteritidis), 가금티푸스의 원인균인 살모넬라 갈리나륨(Salmonella Gallinarum), 추백리 원인균인 살모넬라 플로럼(Salmonella Pullorum), 급성 패혈증 및 돼지 콜레라의 원인균인 살모넬라 콜레라수이스(Salmonella Choleraesuis) 등의 혈청형을 포함한다. 살모넬라균은 혈청형에 따라 인간뿐만 아니라 가축에게도 질병을 일으킬 수 있는 인수공통 감염원을 포함한다. 살모넬라 갈리나륨과 살모넬라 플로럼은 가금 특이적 감염균으로 가금티푸스와 추백리를 일으켜 가금류의 대량 폐사를 유발할 수 있다. 살모넬라 플로럼은 성계에서는 감염되어도 임상 증상이 없으나 부화된 후대 병아리에게 난계대 전염되어 추백리를 일으키며, 생후 1-2주령에서 가장 높은 폐사율이 나타난다. 주로 회백색의 설사 증세를 보이면서 항문을 막아 배변 곤란을 일으켜 복부가 팽창하고, 그로 인한 패혈증으로 폐사한다. 추백리와 같은 경우 상업화된 예방책이 없으며, 감염된 개체의 색출 및 도태를 통해서만 질병의 예방이 가능하다. 또한, 살모넬라 콜레라수이스(Salmonella Choleraesuis)는 돼지에 감염되어 돼지 콜레라를 일으킬 수 있어 돼지 콜레라균으로 잘 알려져 있는 균으로 사람과 동물 모두에게 감염되는 균이다. 이 균은 살모넬라 타이피수이스(Salmonella Typhisuis)와 함께 살모넬라에 의한 급성 패혈증을 일으키며, 살모넬라 감염에 의한 돼지의 급성 또는 만성의 소화기 전염병은 돼지 파라타이포이드(paratyphoid)라 불리우며, 위장염 및 패혈증을 동반하고 주로 비육기에 많이 발생한다. 이 균에 의한 질병의 발생은 계절적으로는 주로 여름에 흔히 발생하며 급성패혈증형은 2~4개월령의 어린 돼지에서 흔히 발생하며, 주된 증상은 체온상승(41~42℃), 원기소실과 식욕감퇴, 귀 주위와 다리 부위에 청색증(cyanosis)이 생기며, 발병 2~4일 이내에 대부분 폐사된다. 급성 장염형은 비육기 가축에 주로 발생되며 식욕이 일정하지 않고 심한 수양성 설사와 고열, 원기쇠약, 폐렴 및 신경증상을 동반하며 중증의 경우 피부변색이 나타난다. 만성 장염형은 가축이 계속적인 설사로 인하여 심하게 여위어 있고 초기 황백색 또는 회백색의 연변에서 점차적으로 젤라틴 양의 점액성 설사로 변하고 설사변은 장점막상피세포의 괴사편을 함유하고 있으며 간혹 혈액이 섞여 있는 경우도 있다. 국내의 경우 상기 균에 의한 질병 발생은 빈도가 매우 낮은 것으로 보고되고 있으나, 질병이 발생하면 전염성 및 피해가 크게 나타날 수 있다. 또한, 살모넬라균이 전염되는 경우의 대부분이 그렇듯이 오염된 원료사료나 물 또는 별 증상 없이 균을 보균하고 있는 성돈이 중요한 전염원이 될 수 있다. Salmonella (Salmonella) is a facultative anaerobic bacteria belonging to gram-negative enteric bacteria and a bacillus which does not form a spore. Salmonella is a pathogenic microorganism that infects humans as well as humans, including pigs, cows, and chickens, causing disease, causing food poisoning in humans, and causing various forms of salmonellosis in animals. Salmonella enterica is a serotype of Salmonella Typhi which causes typhoid fever by serological classification, Salmonella Typhimurium which is a causative organism of mouse typhus, Salmonella Enteritidis which is enteritis species, Salmonella enteritidis includes the causative agent of typhoid Salmonella Galina volume (Salmonella gallinarum), chubaekri causative agent of salmonellosis flow column (Salmonella Pullorum), acute septicemia and cholera, salmonella can be a causative agent of swine fever serotypes devices such as (Salmonella choleraesuis). Salmonella contains common infectious agents that can cause disease not only in humans but also in livestock, depending on the serotype. Salmonella gallinarum and Salmonella florum are poultry-specific infectious agents that cause poultry typhus and mullet to cause massive deaths in poultry. Salmonella fl rum has no clinical symptoms even when infected in the sex system, but it is transmitted to the hatching chick after hatching, causing the mulberry tree and the highest mortality at 1-2 weeks of age. Mainly grayish white diarrhea with symptoms of obstructing the anus to cause difficulties in the abdomen to swell, resulting in sepsis caused by death. There are no commercialized preventive measures such as shingae, and disease can be prevented only through detection and culling of infected individuals. In addition, Salmonella Choleraesuis is a well-known organism of pig cholera that can infect pigs and cause pig cholera. The bacterium, along with Salmonella Typhisuis, causes acute sepsis by Salmonella, and the acute or chronic epidemic of the swine caused by Salmonella infection is called paratyphoid pig, accompanied by gastroenteritis and sepsis It occurs mainly in the finishing period. Acute sepsis is common in young pigs aged 2 to 4 months, and the main symptom is elevation of body temperature (41 ~ 42 ℃), loss of raw silk and appetite, Cyanosis develops around the ears and legs, and most deaths occur within 2-4 days of onset. Acute intestinal type occurs mainly in the fattening livestock. It is not constant in appetite, and it is accompanied by severe watery diarrhea, high fever, weakness, pneumonia and neurological symptoms. In chronic enteritis type, livestock is severely ovarian due to persistent diarrhea, gradually changing to gelatinous mucoidous diarrhea in early yellowish white or grayish white color, diarrhea containing necrotic part of intestinal epithelium, occasionally mixed blood There is also. In Korea, it is reported that the incidence of diseases caused by the above-mentioned bacteria is extremely low. However, when the disease occurs, the infectivity and the damage may be large. In addition, as with most Salmonella infections, contaminated feedstuffs, water, or stigmatizing bacteria without symptoms can be important source of contamination.

현재 살모넬라 감염증을 예방 및 치료하기 위해 항생제를 주로 사용하고 있으나 살모넬라는 동물에 감염 시 세포 내에 침투하여 증식하고 감염하는 경우가 많아 항생제나 약제, 기타 생균제가 침투하여 작용하기는 어려우며, 최근 많은 분야에서 항생제 내성에 대한 문제가 발생되고 있어 이에 대한 원인을 항생제 오남용으로 규명하고 항생제를 충분히 사용하지 못하게 되었다. 이에 따라 산업동물의 배합 사료 내에 성장촉진제로 사용하는 항생제를 금지하기 시작하였고, 유럽연합에서는 2006년부터, 우리나라에서는 2011년 하반기부터 항생제 사용을 규제하기 시작하였다. 또한 항생제가 없는 안전한 먹거리에 대한 소비자의 요구가 증대되고 있어 점차 항생제 사용이 줄어들고 있다. 세균을 제어하는 항생제의 사용이 줄어듦에 따라 세균성 질병의 발생이 증가하고 있어 항생제를 사용하지 않고 세균성 질병을 제어하는 방법에 대한 요구가 늘어나고 있다. 이러한 연구 중 하나가 자연계에 존재하는 세균을 특이적이고 효과적으로 사멸시키는 박테리오파지를 이용하는 방법이다. Currently, antibiotics are mainly used for the prevention and treatment of Salmonella infectious diseases. However, Salmonella is infected and penetrates into cells when infected with an animal. Therefore, it is difficult for antibiotics, medicines and other probiotics to penetrate and act, There is a problem about antibiotic resistance, so the reason for this is due to abuse of antibiotics and the use of antibiotics is not enough. As a result, antibiotics used as growth promoters in industrial animal feeds began to be banned. In the EU, in 2006, Korea began regulating the use of antibiotics in the second half of 2011. Consumer demand for safe food without antibiotics is also increasing, and the use of antibiotics is gradually diminishing. As the use of antibiotics to control bacteria decreases, the incidence of bacterial diseases is increasing, and there is a growing demand for methods to control bacterial diseases without the use of antibiotics. One of these studies is the use of bacteriophages that specifically and effectively kill bacteria in the natural world.

박테리오파지(bacteriophage)는 특정 세균을 감염시켜 감염된 세균의 성장을 억제하고 저해하는 세균 특이적 바이러스를 의미한다. 박테리오파지는 박테리아에 감염(infection)한 후 박테리아 세포 내부에서 증식을 하고, 증식 후 자손 박테리오파지들이 박테리아 밖으로 나올 때 숙주인 박테리아의 세포벽을 파괴하는 방식으로 박테리아를 사멸시키는 능력을 갖고 있다. 박테리오파지의 박테리아 감염 방식은 매우 특이성이 높아서 특정 박테리아에 감염할 수 있는 박테리오파지의 종류는 일부로 한정된다. 즉, 특정 박테리오파지는 특정 범주의 박테리아에만 감염할 수 있고 이로 인하여 특정 박테리오파지는 특정 박테리아만을 사멸시키며 다른 박테리아에는 영향을 주지 않는다. 따라서 최근 세균성 질환의 대처 방안으로 박테리오파지(bacteriophage)의 활용이 크게 주목을 받고 있다. 특히 2000년 이후에 항생제 내성균의 증가로 인하여 기존 항생제의 한계성이 나타나고, 기존 항생제의 대체 물질로의 개발 가능성이 부각되면서 다시 박테리오파지가 항-박테리아제로 주목을 받고 있다.Bacteriophages are bacterial-specific viruses that infect certain bacteria and inhibit and inhibit the growth of infected bacteria. Bacteriophages have the ability to kill bacteria by infecting bacteria, multiplying inside bacterial cells, and destroying the cell walls of the host bacteria when the progeny bacteriophages come out of the bacteria after proliferation. The bacteriophage infection method of bacteriophage is highly specific, so the type of bacteriophage that can infect a specific bacterium is limited to some. That is, certain bacteriophages can infect only a specific category of bacteria, which causes certain bacteriophages to kill only certain bacteria and not other bacteria. Recently, the use of bacteriophage has attracted much attention as a countermeasure against bacterial diseases. Especially, since 2000, the limit of existing antibiotics has appeared due to the increase of antibiotic resistant bacteria, and bacteriophage is attracting attention as an anti - bacterial agent again with the possibility of development as a substitute for existing antibiotics.

그러나 현재까지 양돈이나 양계 산업에 막대한 경제적 피해를 일으키고, 사람까지도 감염시킬 수 있는 살모넬라균에 의한 감염증을 예방 또는 치료하기 위한 신규한 박테리오파지에 대한 연구는 여전히 부족한 실정이다. 따라서 살모넬라균에 특이적인 용균활성을 갖는 박테리오파지 및 이의 응용에 대한 기술 개발이 필요하다. However, there is still a lack of research on new bacteriophages to prevent or treat infectious diseases caused by Salmonella which can cause infectious damage to swine and poultry industry and infect people. Therefore, it is necessary to develop a technology for bacteriophage having a lytic activity specific to Salmonella and its application.

이에 본 발명자들은 살모넬라균에 특이적인 용균활성을 갖는 박테리오파지를 분리하고 분리된 박테리오파지의 형태적 및 유전적 특성을 분석하여 상기 박테리오파지가 다양한 살모넬라균을 선택적으로 사멸시킬 수 있음을 확인함으로써 본 발명을 완성하였다.Accordingly, the present inventors have isolated the bacteriophage having a lytic activity specific to Salmonella and analyzed the morphological and genetic characteristics of the separated bacteriophage to confirm that the bacteriophage can selectively kill a variety of Salmonella, thereby completing the present invention Respectively.

본 발명의 목적은 살모넬라균에 특이적인 사멸능을 갖는, 서열번호 1로 표시되는 염기서열로 이루어진 박테리오파지 SG1을 제공하는 것이다.It is an object of the present invention to provide a bacteriophage SG1 comprising the nucleotide sequence shown in SEQ ID NO: 1, which has a killing activity specific to Salmonella.

본 발명의 또 다른 목적은 상기 박테리오파지 SG1을 포함하는, 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제 또는 세척제를 제공하는 것이다.It is still another object of the present invention to provide an antibiotic composition, composition for feed addition, feed, disinfectant or detergent comprising the bacteriophage SG1.

본 발명의 또 다른 목적은 상기 박테리오파지 SG1을 개체에 투여하는 단계를 포함하는, 살모넬라균에 의한 감염성 질병의 예방 또는 치료 방법을 제공하는 것이다.Yet another object of the present invention is to provide a method for preventing or treating an infectious disease caused by Salmonella, comprising the step of administering the bacteriophage SG1 to a subject.

상기 목적을 달성하기 위하여, 본 발명은 살모넬라균에 특이적인 사멸능을 갖는, 서열번호 1로 표시되는 염기서열로 이루어진 박테리오파지 SG1을 제공한다.In order to achieve the above object, the present invention provides a bacteriophage SG1 comprising the nucleotide sequence shown in SEQ ID NO: 1, which has a killing activity specific to Salmonella.

또한, 본 발명은 상기 박테리오파지 SG1을 포함하는, 항생용 조성물을 제공한다.In addition, the present invention provides an antibiotic composition comprising the bacteriophage SG1.

또한, 본 발명은 상기 박테리오파지 SG1을 포함하는, 사료 첨가용 조성물을 제공한다.Further, the present invention provides a composition for feed addition comprising the bacteriophage SG1.

또한, 본 발명은 상기 박테리오파지 SG1을 포함하는, 소독제를 제공한다.The present invention also provides a disinfectant comprising the bacteriophage SG1.

또한, 본 발명은 상기 박테리오파지 SG1을 포함하는, 세척제를 제공한다.The present invention also provides a cleaning agent comprising the bacteriophage SG1.

또한, 본 발명은 상기 박테리오파지 SG1을 개체에 투여하는 단계를 포함하는, 살모넬라균에 의한 감염성 질병의 예방 또는 치료 방법을 제공한다.In addition, the present invention provides a method for preventing or treating an infectious disease caused by Salmonella, comprising the step of administering the bacteriophage SG1 to an individual.

본 발명의 박테리오파지 SG1을 이용한 살모넬라균에 의한 감염성 질병의 예방 또는 치료 방법은 기존의 항생제 등의 화학물질에 비해 살모넬라균에 대한 특이성이 매우 높고, 상기 박테리오파지 SG1은 살모넬라균에 감염하여 살모넬라균 내에서 증식함으로써 용균 활성이 우수하고 물리화학적 자극에 강하다는 장점을 가지고 있다. 또한 본 발명의 박테리오파지 SG1은 사람, 동물, 식물 등 세균 외의 다른 숙주에는 감염되지 않으므로, 항생제의 오남용으로 인한 항생제 내성균의 문제점, 식품 내의 항생제의 잔류 문제, 광범위한 숙주범위의 문제점을 해결할 수 있는 장점이 있다. 따라서, 본 발명의 박테리오파지 SG1은 다양한 살모넬라균에 의한 감염성 질병의 예방 또는 치료, 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제, 또는 세척제 분야에서 다양하게 사용될 수 있다.The method for preventing or treating infectious diseases caused by Salmonella using the bacteriophage SG1 of the present invention is highly specific to Salmonella than the chemical substances such as existing antibiotics, and the bacteriophage SG1 is infected with Salmonella, It has an advantage that it is excellent in lytic activity and strong against physicochemical stimulation by proliferation. In addition, since the bacteriophage SG1 of the present invention is not infected by any host other than bacteria such as humans, animals and plants, it can solve problems of antibiotic resistant bacteria caused by abuse of antibiotics, residual antibiotics in food, have. Accordingly, the bacteriophage SG1 of the present invention can be used in various fields in the field of preventing or treating infectious diseases caused by various Salmonella, antibiotic composition, composition for feed addition, feed, disinfectant, or detergent.

도 1은 박테리오파지 SG1의 살모넬라 갈리나륨에 대한 용균반 형성 활성을 확인한 결과를 나타낸 도이다.
도 2는 전자 현미경을 통해 박테리오파지 SG1의 형태학적 특성을 확인한 결과를 나타낸 도이다.
도 3은 박테리오파지 SG1의 단백질 패턴을 SDS-PAGE를 통해 확인한 결과를 나타낸 도이다.
도 4는 박테리오파지 SG1의 pH 안정성을 확인한 결과를 나타낸 도이다.
도 5는 박테리오파지 SG1의 열 안정성을 확인한 결과를 나타낸 도이다.BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a graph showing the result of confirming the activity of the bacteriophage SG1 to form a galactosyltransferase against Salmonella gallinarium. FIG.
FIG. 2 is a graph showing the morphological characteristics of the bacteriophage SG1 through an electron microscope.
3 is a graph showing the result of SDS-PAGE of the protein pattern of bacteriophage SG1.
4 is a graph showing the results of confirming the pH stability of the bacteriophage SG1.
5 is a diagram showing the result of checking the thermal stability of the bacteriophage SG1.

이하, 본 발명에 대해 상세히 설명한다.Hereinafter, the present invention will be described in detail.

본 발명은 살모넬라균에 특이적인 사멸능을 갖는, 서열번호 1로 표시되는 염기서열로 이루어진 박테리오파지 SG1을 제공한다.The present invention provides a bacteriophage SG1 comprising the nucleotide sequence shown in SEQ ID NO: 1, which has a killing activity specific to Salmonella.

본 발명에서, 용어 박테리오파지(bacteriophage)는 특정 세균에 감염하여 당해 세균의 성장을 억제하고 저해하는 세균 특이적 바이러스로, 단일 혹은 이중 사슬의 DNA 또는 RNA를 유전 물질로 포함하는 바이러스를 의미한다.In the present invention, the term bacteriophage refers to a bacterium-specific virus that infects a specific bacterium and inhibits and inhibits the growth of the bacterium, and includes a single or double-stranded DNA or RNA as a genetic material.

본 발명에서, 상기 살모넬라균은 살모넬라 갈리나륨(Salmonella Gallinarum), 살모넬라 플로럼(Salmonella Pullorum), 살모넬라 콜레라수이스(Salmonella Choleraesuis), 살모넬라 엔테리티디스(Salmonella Enteritidis) 및 살모넬라 티피뮤리움(Salmonella Typhimurium)으로 구성된 군으로부터 선택된 1종 이상 일 수 있으며, 바람직하게는 살모넬라 갈리나륨(Salmonella Gallinarum), 살모넬라 플로럼(Salmonella Pullorum) 또는 살모넬라 콜레라수이스(Salmonella Choleraesuis)이다. In the present invention, the Salmonella is selected from the group consisting of Salmonella Gallinarum, Salmonella Pullorum, Salmonella Choleraesuis, Salmonella Enteritidis, and Salmonella Typhimurium. And preferably at least one selected from the group consisting of Salmonella Gallinarum, Salmonella Pullorum or Salmonella Choleraesuis.

본 발명의 박테리오파지 SG1 전체 유전자의 크기는 169,805 bp 이며, GC함량이 36%, 전체 ORFs의 수는 269개이다. 상기 박테리오파지 SG1은 살모넬라균, 특히 살모넬라 갈리나륨, 살모넬라 플로럼 및 살모넬라 콜레라수이스에 대해 용균활성이 탁월하다. 또한, 상기 박테리오파지 SG1은 210-230 nm의 크기로, 정이십면체의 머리를 가지며 수축성의 꼬리를 가지는 형태인 마이오비리대(Myoviridae)에 속한다. 본 발명의 박테리오파지 SG1의 단백질 패턴 분석 결과 75 kDa, 58 kDa, 50 kDa, 32 kDa, 25 kDa, 그리고 19 kDa 크기의 단백질을 포함하는 것을 확인하였다. 또한 상기 박테리오파지 SG1은 열 및 pH에 대한 안정성이 우수한 특성을 가지고 있다.The size of the whole gene of the bacteriophage SG1 of the present invention is 169,805 bp, the GC content is 36% and the total ORFs is 269. The bacteriophage SG1 has an excellent lytic activity against Salmonella, especially Salmonella Galiumarium, Salmonella Florum and Salmonella cholera strain. In addition, the bacteriophage SG1 belongs to Myoviridae, which has a size of 210-230 nm and has a conical twin-headed head and a contractile tail. Protein pattern analysis of the bacteriophage SG1 of the present invention confirmed that it contained 75 kDa, 58 kDa, 50 kDa, 32 kDa, 25 kDa and 19 kDa proteins. The bacteriophage SG1 has excellent stability against heat and pH.

본 발명의 박테리오파지 SG1은 서열번호 1로 표시되는 염기서열을 전체 유전자의 전체 또는 일부로서 포함할 수 있다. 또한, 본 발명의 박테리오파지 SG1은 서열번호 1로 표시되는 염기서열, 및 상기 염기서열의 기능적 동등물로 이루어질 수 있다. 상기 기능적 동등물이란 염기서열의 변형, 치환의 결과, 상기 서열번호 1로 표시되는 염기서열과 적어도 70% 이상, 바람직하게는 80% 이상, 더욱 바람직하게는 90% 이상, 더더욱 바람직하게는 95% 이상의 서열 상동성을 갖는 것으로, 서열번호 1로 표시되는 염기서열과 실질적으로 동질의 생리활성을 나타내는 서열을 의미한다.The bacteriophage SG1 of the present invention may include the nucleotide sequence shown in SEQ ID NO: 1 as a whole or a part of the entire gene. In addition, the bacteriophage SG1 of the present invention may comprise the nucleotide sequence shown in SEQ ID NO: 1 and the functional equivalent of the nucleotide sequence. The functional equivalent means at least 70% or more, preferably 80% or more, more preferably 90% or more, still more preferably 95% or more of the nucleotide sequence shown in SEQ ID NO: 1 as a result of modification or substitution of the nucleotide sequence. Or more and having substantially the same physiological activity as the nucleotide sequence shown in SEQ ID NO: 1.

상기와 같은 살모넬라균 특이적 용균활성, 내산성, 내염기성 및 내열성은 본 발명의 박테리오파지 SG1을 살모넬라균에 의한 감염성 질병의 예방 및 치료용 조성물, 및 상기 박테리오파지 SG1을 유효성분으로 포함하는 다양한 제품에 적용함에 있어, 다양한 온도 및 pH 범위의 적용이 가능하게 한다.The salmonella-specific lytic activity, acid resistance, basic basicity and heat resistance of the present invention can be effectively applied to a composition for preventing and treating infectious diseases caused by Salmonella bacteria and various products containing the bacteriophage SG1 as an active ingredient This makes it possible to apply various temperature and pH ranges.

본 발명의 박테리오파지 SG1은 도계장, 양계장 및 산란계 농장의 분변과 농장 부근의 하수로부터 시료를 채취하여 분리한 박테리오파지로서, 본 발명자는 박테리오파지 SG1로 명명하고 2016년 10월 21일에 한국미생물보존센터 (Korean Culture Center of Microorganisms, 서울, 한국)에 기탁하여, 기탁번호 KFCC11698P를 부여받았다.The bacteriophage SG1 of the present invention is a bacteriophage obtained by collecting a sample from feces of a slaughterhouse, a poultry farm and a laying farm and a sewage near a farm. The inventor named the bacteriophage SG1 and on October 21, 2016, Culture Center of Microorganisms, Seoul, Korea), and received the deposit number KFCC11698P.

또한, 본 발명은 상기 박테리오파지 SG1을 포함하는, 살모넬라균에 의한 감염성 질병의 예방 또는 치료용 약학적 조성물을 제공한다.The present invention also provides a pharmaceutical composition for preventing or treating an infectious disease caused by Salmonella, which comprises the bacteriophage SG1.

본 발명에서, 상기 살모넬라균은 살모넬라 갈리나륨(Salmonella Gallinarum), 살모넬라 플로럼(Salmonella Pullorum), 살모넬라 콜레라수이스(Salmonella Choleraesuis), 살모넬라 엔테리티디스(Salmonella Enteritidis) 및 살모넬라 티피뮤리움(Salmonella Typhimurium)으로 구성된 군으로부터 선택된 1종 이상 일 수 있으며, 바람직하게는 살모넬라 갈리나륨(Salmonella Gallinarum), 살모넬라 플로럼(Salmonella Pullorum) 또는 살모넬라 콜레라수이스(Salmonella Choleraesuis)이다. In the present invention, the Salmonella is selected from the group consisting of Salmonella Gallinarum, Salmonella Pullorum, Salmonella Choleraesuis, Salmonella Enteritidis, and Salmonella Typhimurium. And preferably at least one selected from the group consisting of Salmonella Gallinarum, Salmonella Pullorum or Salmonella Choleraesuis.

본 발명의 박테리오파지 SG1은 다양한 살모넬라균에 특이적인 사멸능을 가지므로, 상기 균들에 의한 감염성 질병의 예방 또는 치료용 약학적 조성물에 사용될 수 있다. 본 발명의 박테리오파지 SG1은 살모넬라균 중에서도 살모넬라 갈리나륨, 살모넬라 플로럼 및 살모넬라 콜레라수이스에 더욱 특이적이므로, 본 발명은 상기 살모넬라균의 감염에 의한 감염성 질병의 예방 또는 치료에 이용될 수 있으나, 이에 제한되는 것은 아니다.Since the bacteriophage SG1 of the present invention has a specific killing activity specific to various Salmonella strains, it can be used in a pharmaceutical composition for the prevention or treatment of infectious diseases caused by the abovementioned fungi. Since the bacteriophage SG1 of the present invention is more specific to Salmonella gallinarum, Salmonella florum and Salmonella cholera strains among Salmonella strains, the present invention can be used for the prevention or treatment of infectious diseases caused by the infection of Salmonella strains, It is not.

본 발명에서, 살모넬라균에 의한 감염성 질병은 유행성 또는 급성으로 발병하는 전염성 질환을 통칭하는 개념으로, 살모넬라증 외에, 식중독, 위염, 장염, 폐렴, 패혈증, 돼지 콜레라, 추백리 및 가금티푸스 등을 포함하나, 이에 제한되는 것은 아니다.In the present invention, infectious diseases caused by Salmonella include the food poisoning, gastritis, enteritis, pneumonia, septicemia, porcine cholera, papaya, poultry typhus and the like, in addition to salmonellosis, But is not limited thereto.

상기 살모넬라증은 살모넬라균 감염에 의해 발열, 두통, 설사, 구토 등을 수반하는 증상을 총칭하는 것으로, 살모넬라증은 장티푸스와 같은 증세를 나타내는 패혈증형과 식중독 증세를 나타내는 급성 위장염형으로 대별되며, 장염, 식중독, 급성 균혈증 등이 포함된다.Salmonellosis is a general term referring to symptoms accompanied by fever, headache, diarrhea, and vomiting due to Salmonella infection. Salmonellosis is classified into septicemia, which is similar to typhoid fever, and acute gastroenteritis, which is a food poisoning symptom. , Acute bacteremia, and the like.

바람직하게, 상기 살모넬라 갈리나륨에 의한 감염성 질병은 가금티푸스일 수 있으나, 이에 제한되는 것은 아니다.Preferably, the infectious disease caused by the Salmonella gallinarum may be poultry typhus, but is not limited thereto.

바람직하게, 상기 살모넬라 플로럼에 의한 감염성 질병은 추백리 일 수 있으나, 이에 제한되는 것은 아니다.Preferably, the infectious disease caused by the Salmonella fl rum can be, but is not limited to, shrapnel.

바람직하게, 상기 살모넬라 콜레라수이스에 의한 감염성 질병은 위염, 장염, 패혈증 및 돼지 콜레라일 수 있으나, 이에 제한되는 것은 아니다. Preferably, the infectious disease caused by Salmonella cholera strains is, but is not limited to, gastritis, enteritis, sepsis and porcine cholera.

바람직하게, 상기 살모넬라 엔테리티디스 또는 살모넬라 티피뮤리움에 의한 감염성 질병은 식중독, 장염, 폐렴 또는 패혈증일 수 있으나, 이에 제한되는 것은 아니다.Preferably, the infectious disease caused by Salmonella enteritidis or Salmonella typhimurium may be food poisoning, enteritis, pneumonia, or sepsis, but is not limited thereto.

본 발명의 약학적 조성물은 1 × 103 내지 1 × 1010 PFU/mL의 박테리오파지를 포함하며, 바람직하게는 1 × 106 내지 1 × 109 PFU/mL의 박테리오파지를 포함한다. 본 발명에 사용된 용어, PFU(plaque forming unit)는 박테리오파지가 플라크를 형성하는 것을 수치화한 단위이다.The pharmaceutical composition of the present invention contains bacteriophage of 1 × 10 3 to 1 × 10 10 PFU / mL, preferably 1 × 10 6 to 1 × 10 9 PFU / mL of bacteriophage. The term " PFU (plaque forming unit) " used in the present invention is a unit in which bacteriophages form a plaque.

본 발명의 용어 예방이란 조성물의 투여로 질병을 억제시키거나 발병을 지연시키는 모든 행위를 의미한다.The term " prophylactic " of the present invention means all actions that inhibit disease or delay the onset of the disease by administration of the composition.

본 발명의 용어 치료란 조성물의 투여로 상기 질병의 증세가 호전되거나 상기 질병의 억제 또는 경감 및 이롭게 변경되는 모든 행위를 의미한다.The term " treatment " of the present invention refers to any action that improves or alleviates or alleviates the symptoms of the disease upon administration of the composition.

본 발명의 약학적 조성물은 약학적으로 허용 가능한 담체를 추가로 포함할 수 있다.The pharmaceutical composition of the present invention may further comprise a pharmaceutically acceptable carrier.

본 발명에서 용어, 약학적으로 허용 가능한 담체란 생물체를 자극하지 않고 투여 화합물의 생물학적 활성 및 특성을 저해하지 않는 담체 또는 희석제를 의미한다. 액상 용액으로 제제화 되는 조성물에 있어서 허용되는 약제학적 담체로는, 멸균 및 생체에 적합한 것으로서, 식염수, 멸균수, 링거액, 완충 식염수, 알부민 주사용액, 덱스트로오스 용액, 말토 덱스트린 용액, 글리세롤, 에탄올 및 이들 성분 중 1성분 이상을 혼합하여 사용할 수 있으며, 필요에 따라 항산화제, 완충액, 정균제 등 다른 통상의 첨가제를 첨가할 수 있다. 또한 희석제, 분산제, 계면활성제, 결합제 및 윤활제를 부가적으로 첨가하여 수용액, 현탁액, 유탁액 등과 같은 주사용 제형, 환약, 캡슐, 과립 또는 정제로 제제화할 수 있다.The term pharmaceutically acceptable carrier, as used herein, means a carrier or diluent that does not irritate the organism and does not interfere with the biological activity and properties of the administered compound. Examples of the pharmaceutical carrier which is acceptable for the composition to be formulated into a liquid solution include sterilized and sterile water, sterile water, Ringer's solution, buffered saline, albumin injection solution, dextrose solution, maltodextrin solution, glycerol, One or more of these components may be mixed and used. If necessary, other conventional additives such as an antioxidant, a buffer, and a bacteriostatic agent may be added. In addition, diluents, dispersants, surfactants, binders, and lubricants may be additionally added to formulate into injectable solutions, pills, capsules, granules or tablets such as aqueous solutions, suspensions, emulsions and the like.

본 발명의 약학적 조성물은 질환 부위에의 도포 또는 분무하는 방법으로 이용할 수 있으며, 그 밖에 비강 분무, 경구 투여 또는 비경구 투여를 통해 투여할 수도 있으며, 비경구 투여의 경우 정맥 내 투여, 복강 내 투여, 근육 내 투여, 피하 투여 또는 국부 투여를 이용하여 투여할 수도 있다.The pharmaceutical composition of the present invention can be used as a method of applying or spraying on a diseased site, or may be administered through nasal spray, oral administration or parenteral administration. In the case of parenteral administration, intravenous administration, intraperitoneal administration Administration, intramuscular, subcutaneous or local administration.

상기 비강 분무의 경우 일정량의 박테리오파지 SG1을 물에 희석하여 분무기나 분무 시스템을 통해 비강으로 흡수 되도록 할 수 있다. 상기 비강 분무를 위한 비강 분무제 또는 호흡기용 제형으로는 에어로졸제 등을 들 수 있다.In the case of the nasal spray, a certain amount of bacteriophage SG1 can be diluted in water and absorbed into the nasal cavity through a sprayer or a spray system. Examples of the nasal spray agent for the nasal spray or the aerosol agent for the respiratory system are mentioned.

상기 비강 분무제 또는 호흡기용 제형은, 수분산된 농축물 또는 습윤 분말을 분산시키기 위한 추진제 및/또는 기타 첨가제를 추가로 포함할 수 있다.The nasal spray or respiratory formulation may further comprise a propellant and / or other additives for dispersing the water-dispersed concentrate or wet powder.

본 발명의 약학적 조성물의 적합한 도포, 분무 및 투여량은 제제화 방법, 투여 방식, 대상이 되는 동물 및 환자의 연령, 체중, 성, 질병 증상의 정도, 음식, 투여시간, 투여 경로, 배설 속도 및 반응 감응성과 같은 요인들에 의해 다양하며, 보통으로 숙련된 의사나 수의사는 목적하는 치료에 효과적인 투여량을 용이하게 결정 및 처방할 수 있다.The appropriate application, spray and dose of the pharmaceutical composition of the present invention may vary depending on factors such as formulation method, administration method, age, body weight, sex, disease symptom level, food, administration time, administration route, Response sensitivities, and the ordinarily skilled physician or veterinarian can readily determine and prescribe dosages effective for the desired treatment.

본 발명의 약학적 조성물을 유효성분으로 포함하는 경구 투여용 제형으로는, 예를 들어 정제, 트로키제, 로렌지, 수용성 또는 유성현탁액, 조제분말 또는 과립, 에멀젼, 하드 또는 소프트 캡슐, 시럽 또는 엘릭시르제로 제제화할 수 있다. 정제 및 캡슐 등의 제형으로 제제화하기 위해, 락토오스, 사카로오스, 솔비톨, 만니톨, 전분, 아밀로펙틴, 셀룰로오스 또는 젤라틴과 같은 결합제, 디칼슘 포스페이트와 같은 부형제, 옥수수 전분 또는 고구마 전분과 같은 붕괴제, 스테아르산 마그네슘, 스테아르산 칼슘, 스테아릴푸마르산 나트륨 또는 폴리에틸렌글리콜 왁스와 같은 윤활유를 포함할 수 있으며, 캡슐 제형의 경우 상기 언급한 물질 외에도 지방유와 같은 액체 담체를 더 함유할 수 있다.Examples of formulations for oral administration comprising the pharmaceutical composition of the present invention as an active ingredient include tablets, troches, lozenges, aqueous or oily suspensions, prepared powders or granules, emulsions, hard or soft capsules, syrups or elixirs It can be formulated into a zero. A binder such as lactose, saccharose, sorbitol, mannitol, starch, amylopectin, cellulose or gelatin, an excipient such as dicalcium phosphate, a disintegrating agent such as corn starch or sweet potato starch, a disintegrant such as magnesium stearate , Calcium stearate, sodium stearyl fumarate or polyethylene glycol wax. In the case of a capsule formulation, in addition to the above-mentioned materials, a liquid carrier such as a fatty oil may be further contained.

본 발명의 약학적 조성물을 유효성분으로 포함하는 비경구 투여용 제형으로는, 피하주사, 정맥주사 또는 근육 내 주사 등의 주사용 형태, 좌제 주입방식 또는 호흡기를 통하여 흡입이 가능하도록 하는 에어로졸제 등 스프레이용으로 제제화할 수 있다. 주사용 제형으로 제제화하기 위해서는 본 발명의 조성물을 안정제 또는 완충제와 함께 물에서 혼합하여 용액 또는 현탁액으로 제조하고, 이를 앰플 또는 바이알의 단위 투여용으로 제제화할 수 있다. 에어로졸제 등의 스프레이용으로 제형화하는 경우, 수분산된 농축물 또는 습윤 분말이 분산되도록 추진제 등이 첨가제와 함께 배합될 수 있다.Examples of the formulations for parenteral administration containing the pharmaceutical composition of the present invention as an active ingredient include injection forms such as subcutaneous injection, intravenous injection or intramuscular injection, aerosol formulations such as a suppository injection method or a respiratory apparatus It can be formulated for spraying. For formulation into injectable formulations, the compositions of the present invention may be formulated as solutions or suspensions in water with stabilizers or buffers in water, and formulated for unitary administration of ampoules or vials. When formulated for spraying, such as an aerosol formulation, a propellant or the like may be formulated with the additive such that the water-dispersed concentrate or wet powder is dispersed.

또한, 본 발명은 상기 박테리오파지 SG1을 포함하는, 항생용 조성물을 제공한다. In addition, the present invention provides an antibiotic composition comprising the bacteriophage SG1.

본 발명에서, 용어 항생용 조성물은 약제 형태로 개체에 제공되어 균을 사멸시킬 수 있는 제제를 의미하며, 방부제, 살균제, 항생제 및 항균제를 총칭하는 것이다. In the present invention, the term antibiotic composition refers to a preparation which can be given to an individual in the form of a drug to kill the bacterium, and collectively refers to preservatives, bactericides, antibiotics and antibacterial agents.

본 발명의 박테리오파지 SG1은 기존 항생제에 비하여 살모넬라균에 대한 특이성이 매우 높으므로, 유익균은 죽이지 않고, 특정 병원균만 사멸시킬 수 있고, 약물 내성 내지 저항성을 유도하지 않아, 기존의 항생물질에 비하여 제품수명(life cycling)이 긴 신규 항생제로서 이용될 수 있다.Since the bacteriophage SG1 of the present invention has a higher specificity to Salmonella than the conventional antibiotics, it does not kill useful bacteria, can kill only specific pathogens, does not induce drug resistance or resistance, (life cycling) can be used as a new antibiotic.

또한, 본 발명은 상기 박테리오파지 SG1을 포함하는, 사료 첨가용 조성물을 제공한다.Further, the present invention provides a composition for feed addition comprising the bacteriophage SG1.

축산, 수산업에서 사용되는 사료 첨가용 항생제는 질병의 예방 목적으로 사용되고 있는데, 예방 목적의 항생제 투여는 내성균 발생 가능성을 높이고 가축에 잔류하는 항생제가 사람에게 전달될 수 있어서 문제이다. 항생제가 육류를 통해 인체에 흡수되면 항생제 내성을 유발해 질병의 확산을 부를 수도 있다. 또한, 사료에 섞어 먹이는 항생제의 종류가 많고 이는 다제 내성균 발생 확률이 높아지는 문제점이 있기 때문에 좀 더 자연 친화적이면서도 기존의 항생제의 사용에서 발생한 문제를 해결할 새로운 사료 첨가용 항생물질로서 본 발명의 상기 박테리오파지 SG1을 이용할 수 있다.Antibiotics for feed additive used in animal husbandry and fisheries are used for the prevention of diseases. The administration of antibiotics for prevention is problematic because it increases the possibility of producing resistant bacteria and antibiotics remaining in the livestock can be delivered to humans. If antibiotics are absorbed into the body through meat, they may cause antibiotic resistance and spread the disease. In addition, since there are many types of antibiotics to be mixed with feeds, there is a problem in that the probability of occurrence of multidrug-resistant bacteria is increased. Therefore, the bacteriophage SG1 of the present invention, which is a more natural-friendly antibiotic substance for solving problems arising from the use of existing antibiotics, Can be used.

또한, 본 발명은 상기 사료 첨가용 조성물을 포함하는 사료를 제공할 수 있으며, 본 발명의 사료는 박테리오파지를 사료 첨가제 형태로 따로 제조하여 사료에 혼합시키거나, 사료 제조 시 직접 첨가시켜 제조할 수 있다. 본 발명의 사료 내 박테리오파지는 액상 또는 건조 상태일 수 있으며, 바람직하게는 건조된 분말형태이다. 건조방법은 통풍건조, 자연건조, 분무건조 및 동결건조가 가능하지만, 이에 제한되는 것은 아니다. 본 발명의 박테리오파지는 분말형태로 사료 중량의 0.05 내지 10 중량%, 바람직하게는 0.1 내지 2 중량%의 성분비로 혼합될 수 있다. 또한, 상기 사료는 본 발명의 박테리오파지 외에 사료의 보존성을 높일 수 있는 통상의 첨가제들을 추가로 포함할 수 있다.In addition, the present invention can provide a feed comprising the feed composition, and the feed of the present invention can be prepared by separately preparing bacteriophage as a feed additive and mixing the feed into the feed, . The bacteriophage in the feed of the present invention may be in a liquid or dry state, preferably in the form of a dried powder. Drying methods include, but are not limited to, air drying, natural drying, spray drying and freeze drying. The bacteriophage of the present invention may be mixed in powder form in a composition ratio of 0.05 to 10% by weight, preferably 0.1 to 2% by weight of the feed weight. In addition to the bacteriophages of the present invention, the feed may further include conventional additives that can enhance the preservability of the feed.

본 발명의 사료 첨가용 조성물에는 비병원성의 다른 미생물이 추가로 첨가될 수 있다. 첨가될 수 있는 미생물로는 단백질 분해 효소, 지질 분해 효소 및 당 전환 효소를 생산할 수 있는 바실러스 서브틸리스(Bacillus subtilis)와 같은 고초균, 소의 위와 같은 혐기적 조건에서 생리적 활성 및 유기물 분해능이 있는 락토바실러스 균주(Lactobacillus sp.), 가축의 체중을 증가시키며 우유의 산유량을 늘리고 사료의 소화 흡수율을 높이는 효과를 보여주는 아스퍼질러스 오리자에(Aspergillus oryzae)와 같은 사상균 및 사카로미세스 세레비지에(Saccharomyces cerevisiae)와 같은 효모로 구성된 군으로부터 선택될 수 있다.In the composition for feed addition of the present invention, microorganisms other than non-pathogenic microorganisms may be further added. Examples of microorganisms that can be added include lactobacilli such as Bacillus subtilis capable of producing proteolytic enzymes, lipolytic enzymes and glycosyltransferases, lactobacilli having physiological activity and organic resolution at anaerobic conditions such as bovine, ( Lactobacillus sp.), Filamentous fungi such as Aspergillus oryzae , which increase the body weight of livestock and increase the milk yield of milk and increase digestion rate of feed, and Saccharomyces cerevisiae ). ≪ / RTI >

본 발명의 박테리오파지 SG1을 포함하는 사료에는 식물성으로는 곡물류, 근과류, 식품가공 부산물류, 조류, 섬유질류, 제약 부산물류, 유지류, 전분류, 박류, 곡물부산물류 등이 있으며, 동물성으로는 단백질류, 무기물류, 유지류, 광물성류, 단세포 단백질, 동물성 플랑크톤류, 남은 음식물 등이 있으며 이에 제한되는 것은 아니다.Examples of the feedstuffs containing bacteriophage SG1 of the present invention include cereals, muscle roots, food processing busines, birds, fibers, pharmaceutical buses, oils, fats, But are not limited to, proteins, mineralogy, oils, mineralogy, unicellular proteins, zooplankton, and remnants.

본 발명의 사료 첨가용 조성물에는 품질 저하를 방지하기 위하여 첨가하는 결착제, 유화제, 보존제 등이 포함될 수 있고, 효용 증대를 위하여 사료에 첨가하는 아미노산제, 비타민제, 효소제, 생균제, 향미제, 비단백태질소화합물, 규산염제, 완충제, 착색제, 추출제, 올리고당 등이 포함될 수 있으며, 그 외에도 사료 혼합제 등을 추가로 포함할 수 있다.The composition for feed addition of the present invention may contain a binder, an emulsifying agent, a preservative, etc. added to prevent deterioration of quality. An amino acid, a vitamin, an enzyme, a probiotic, a flavoring agent, A nitrogen compound, a silicate, a buffer, a coloring agent, an extracting agent, an oligosaccharide, etc., and may further include a feed mixture.

또한, 본 발명은 박테리오파지 SG1을 포함하는, 음용수 첨가제를 제공한다.The present invention also provides a drinking water additive comprising bacteriophage SG1.

본 발명의 음용수 첨가제는 상기 박테리오파지 SG1 또는 이를 포함하는 조성물을 음용수 첨가제 형태로 따로 제조하여 사료 또는 음용수에 혼합하는 방식으로 사용되거나, 음용수 제조 시 직접 첨가하는 방식으로 사용할 수 있다. 상기와 같이 음용수에 혼합하여 공급함으로써 지속적으로 살모넬라균의 숫자를 감소시킬 수 있는 효과가 있다.The additive for drinking water of the present invention can be used either in the form of separately preparing the bacteriophage SG1 or a composition containing the bacteriophage SG1 as a drinkable water additive, or in a method of mixing it in a feed or drinking water, or in a method of directly adding it in the production of drinking water. As a result, the number of salmonella bacteria can be continuously reduced by mixing and supplying the drinking water.

본 발명에서 음용수는 특별히 제한되지 아니하며, 당해 기술 분야에서 통상적으로 사용되는 음용수를 사용할 수 있다.In the present invention, the drinking water is not particularly limited, and drinking water commonly used in the art can be used.

또한, 본 발명은 상기 박테리오파지 SG1을 포함하는, 소독제를 제공한다.The present invention also provides a disinfectant comprising the bacteriophage SG1.

다양한 살모넬라균에 특이적 사멸능을 갖는 본 발명의 박테리오파지 SG1을 포함하는 소독제는 병원감염을 막기 위한 병원 및 보건용의 소독제로 유용하게 사용될 수 있고 일반 생활 소독제, 식품 및 조리 장소 및 설비의 소독제, 양계장, 축사 등의 건물, 축체, 음수, 깔짚, 난좌, 운반차량, 식기 등의 각종 생육 용품의 소독 등에 사용될 수 있다.The disinfectant containing the bacteriophage SG1 of the present invention having specific abilities to kill various Salmonella species can be effectively used as a disinfectant for hospitals and healthcare to prevent hospital infection and can be used as a disinfectant for general living disinfectants, And can be used for disinfecting various kinds of growing equipment such as poultry houses, housing buildings such as houses, shaft bodies, water, litter, stairs, transportation vehicles, tableware and the like.

또한, 본 발명은 상기 박테리오파지 SG1을 포함하는, 세척제를 제공한다.The present invention also provides a cleaning agent comprising the bacteriophage SG1.

본 발명의 박테리오파지 SG1은 다양한 살모넬라균에 특이적 사멸능을 가지므로, 상기 살모넬라균에 노출되었거나 노출될 가능성이 있는 가축의 피부 표면 또는 신체 각 부위 등을 세척하는 용도로도 사용될 수 있다.Since the bacteriophage SG1 of the present invention has a specific killing power against various Salmonella bacteria, it can be used for washing the skin surface or body parts of the livestock which are exposed or exposed to the Salmonella.

또한, 본 발명은 상기 박테리오파지 SG1을 개체에 투여하는 단계를 포함하는, 살모넬라균에 의한 감염성 질병의 예방 또는 치료 방법을 제공한다.In addition, the present invention provides a method for preventing or treating an infectious disease caused by Salmonella, comprising the step of administering the bacteriophage SG1 to an individual.

상기 살모넬라균은 살모넬라 갈리나륨(Salmonella Gallinarum), 살모넬라 플로럼(Salmonella Pullorum), 살모넬라 콜레라수이스(Salmonella Choleraesuis), 살모넬라 엔테리티디스(Salmonella Enteritidis) 및 살모넬라 티피뮤리움(Salmonella Typhimurium)으로 구성된 군으로부터 선택된 1종 이상 일 수 있으며, 바람직하게는 살모넬라 갈리나륨(Salmonella Gallinarum), 살모넬라 플로럼(Salmonella Pullorum) 또는 살모넬라 콜레라수이스(Salmonella Choleraesuis)이다. The Salmonella is selected from the group consisting of Salmonella Gallinarum, Salmonella Pullorum, Salmonella Choleraesuis, Salmonella Enteritidis and Salmonella Typhimurium. And more preferably at least one selected from the group consisting of Salmonella Gallinarum, Salmonella Pullorum or Salmonella Choleraesuis.

본 발명의 방법은 살모넬라균에 의한 감염성 질병, 예컨대 유행성 또는 급성으로 발병하는 전염성 질환으로, 살모넬라증 외에 식중독, 위염, 장염, 폐렴, 패혈증, 돼지 콜레라, 추백리 및 가금티푸스가 발생한 개체 또는 발생 위험이 있는 개체에 박테리오파지 SG1을 투여하는 단계를 포함한다. The method of the present invention is applicable to infectious diseases caused by Salmonella, for example, epidemic diseases that occur epidemic or acute, such as food poisoning, gastritis, enteritis, pneumonia, sepsis, pig cholera, Administering bacteriophage SG1 to the subject.

본 발명에서, 용어 "개체"는 살모넬라균에 의한 감염성 질병이 발병될 수 있는 모든 개체를 의미하는 것으로 인간을 포함한 포유동물, 가축류 또는 가금류를 포함하나, 이에 제한되는 것은 아니다. 본 발명의 박테리오파지 SG1은 가금티푸스의 원인인 살모넬라 갈리나륨, 추백리의 원인인 살모넬라 플로럼에 특이적 사멸능을 가지는바, 바람직하게는 가금류에 투여될 수 있다. 또한, 본 발명의 박테리오파지 SG1은 돼지 콜레라의 원인인 살모넬라 콜레라수이스에 특이적 사멸능을 가지는바, 바람직하게는 돼지에 투여될 수 있다. In the present invention, the term "individual " means any individual to which an infectious disease caused by Salmonella can be developed, including, but not limited to, mammals including humans, livestock or poultry. The bacteriophage SG1 of the present invention has a specific killing activity on salmonella florum, which is the cause of salmonella gallinarium and shingae, which is a cause of poultry typhus, and can be preferably administered to poultry. In addition, the bacteriophage SG1 of the present invention has a specific killing activity against Salmonella cholera strain, which is a cause of swine cholera, and can be preferably administered to pigs.

상기 용어 "가축류"는 인간에 의하여 순화, 개량되어 사람과 함께 공동생활을 하는 유용한 동물을 지칭하는 개념으로, 예를 들어, 돼지, 소, 닭, 말, 오리 또는 개 등을 포함하나, 이에 제한되는 것은 아니다.The term " livestock animal "is intended to refer to useful animals that are refined and improved by humans to co-live with humans, including, for example, pigs, cows, chickens, horses, ducks or dogs, It is not.

상기 용어 "가금류"는, 가축 중 조류에 속하는 동물을 총칭하여 이르는 개념으로, 예를 들어, 닭, 오리, 꿩, 메추리, 타조, 거위 또는 칠면조 등을 포함하나, 이에 제한되는 것은 아니다.The term "poultry" includes, but is not limited to, chicken, duck, pheasant, queen, ostrich, goose or turkey.

본 발명의 방법에서 상기 박테리오파지 SG1 또는 조성물은 약학적 제제의 형태로 개체에 투여되거나, 가축의 사료 또는 음용수에 혼합하여 이를 섭식시키는 방법을 통해 투여될 수 있다.In the method of the present invention, the bacteriophage SG1 or the composition may be administered to a subject in the form of a pharmaceutical preparation, or mixed with feed or drinking water of a livestock and fed.

본 발명의 방법에서 상기 박테리오파지 SG1 또는 조성물의 투여 경로는 목적 조직에 도달할 수 있는 한 경구 또는 비경구의 다양한 경로를 통하여 투여될 수 있으며, 구체적으로, 구강, 직장, 국소, 정맥 내, 복강 내, 근육 내, 동맥 내, 경피, 비측 내, 흡입 등을 통해 통상적인 방식으로 투여될 수 있다.In the method of the present invention, the administration route of the bacteriophage SG1 or composition may be administered through various routes of oral or parenteral administration, as long as it can reach the target tissues. Specifically, oral administration, rectal administration, topical administration, intravenous, Intravenous, intramuscular, intraarterial, transdermal, intranasal, inhalation, and the like.

본 발명의 방법에 투여되는 상기 박테리오파지 SG1의 적합한 총 1일 사용량은 올바른 의학적 판단범위 내에서 처치의에 의해 결정될 수 있다는 것은 당업자에게 자명한 일이다. 특정 개체에 대한 구체적인 치료적 유효량은 달성하고자 하는 반응의 종류와 정도, 환자의 연령, 체중, 일반 건강 상태, 성별 및 식이, 투여시간, 투여 경로 및 조성물의 분비율, 치료기간, 구체적 조성물과 함께 사용되거나 동시 사용되는 약물을 비롯한 다양한 인자와 의약 분야에 잘 알려진 유사 인자에 따라 다르게 적용하는 것이 바람직하다.It will be apparent to those skilled in the art that the appropriate total daily usage of the bacteriophage SG1 administered in the methods of the present invention can be determined by treatment within the scope of sound medical judgment. The specific therapeutically effective amount for a particular individual will depend upon the type and extent of the response to be achieved, the age, weight, general health, sex and diet of the patient, the time of administration, the route of administration and the fraction of the route of administration, It is preferable to apply differently depending on various factors including drugs used or co-used and similar factors well known in the medical field.

본 명세서에서 달리 정의되지 않은 용어들은 본 발명이 속하는 기술분야에서 통상적으로 사용되는 의미를 갖는 것이다.Terms not otherwise defined herein have meanings as commonly used in the art to which the present invention belongs.

이하, 본 발명을 실시예, 제제예에 의해 상세히 설명한다. 단, 하기 실시예, 제제예는 본 발명을 예시하는 것일 뿐 본 발명의 내용이 하기 실시예, 제제예에 한정되는 것은 아니다.Hereinafter, the present invention will be described in detail with reference to Examples and Preparation Examples. However, the following examples and preparative examples are merely illustrative of the present invention, and the content of the present invention is not limited to the following examples and preparative examples.

실시예Example 1:  One: 신규한New 박테리오파지의 분리 및 배양 Isolation and culture of bacteriophage

1.1 박테리오파지의 스크리닝 및 단일 박테리오파지의 분리1.1 Screening of bacteriophages and isolation of single bacteriophages

살모넬라 갈리나륨에 특이적인 박테리오파지를 스크리닝 및 분리하기 위해서 용균반 분석을 수행하였다. 시료는 박테리오파지가 존재할 것으로 예상되는 도축장, 양계 및 산란계 농장의 분변과 농장 부근의 하수로부터 채취하였으며, 박테리오파지 분리에 사용된 살모넬라 갈리나륨은 (주)옵티팜에서 채취한 야외 시료로부터 분리 동정된 것을 사용하였다.Sputum analysis was performed to screen and isolate bacteriophages specific for Salmonella gallinarum. Samples were collected from the feces of the slaughterhouse, poultry and laying field farms where the bacteriophages are expected to be present and the sewage near the farm. Salmonella gallinarium used for bacteriophage isolation was isolated from outdoor samples collected from Opti Pharm Co., Ltd. Respectively.

구체적으로, 채취한 시료를 균질화 한 후 살모넬라 갈리나륨과 함께 35℃에서 24시간 동안 진탕배양 하였다. 상기 배양액을 4,000 rpm으로 20분간 원심분리한 후, 상등액을 공극(pore) 크기가 0.45 μm인 필터를 이용하여 여과하여 시료 여과액을 얻었다. Specifically, the collected samples were homogenized and then cultured with Salmonella gallinarum at 35 DEG C for 24 hours with shaking. The culture solution was centrifuged at 4,000 rpm for 20 minutes, and the supernatant was filtered using a filter having a pore size of 0.45 μm to obtain a sample filtrate.

전배양된 살모넬라 갈리나륨 150 μL를 취해서 멸균된 튜브에 넣고 3 mL의 LB 탑 아가(top agar) [LB 배지(트립톤 10 g/L, 효모 추출물(yeast extract) 5 g/L, NaCl 10 g/L) + 0.6% 아가)]를 첨가하여 잘 혼합한 후 미리 만들어 둔 2% LB 아가 플레이트에 중층하였다. 이를 실온에서 30분간 방치한 후 상기 시료 여과액을 각각 10 μL씩 점적하고, 다시 실온에서 30분간 방치한 후 35℃에서 24시간 동안 배양하여 박테리오파지의 유무를 확인하였다. 150 μL of pre-cultured salmonella gallinarum was placed in a sterilized tube and 3 mL of LB top agar (LB medium (10 g / L of tryptone, 5 g / L of yeast extract, 10 g of NaCl / L) + 0.6% agar] was added thereto, and the mixture was well mixed and then layered on a 2% LB agar plate. After incubation at room temperature for 30 minutes, 10 μL of the sample filtrate was added dropwise, and the mixture was allowed to stand at room temperature for 30 minutes and then incubated at 35 ° C. for 24 hours to confirm presence or absence of bacteriophages.

박테리오파지의 존재를 확인한 시료로부터 박테리오파지를 순수 분리하기 위해서 소프트 아가 오버레이(soft agar overlay)법을 이용하였다. 박테리오파지가 존재하는 것으로 확인된 시료를 식염수로 적절히 희석하여 각 희석단의 시료 희석액 100 μL를 취하고, 대상 세균(살모넬라 갈리나륨) 배양액 150 μL에 혼합한 후 0.6% LB 탑 아가 3 mL을 첨가하여 잘 혼합한 뒤, 미리 만들어 둔 2% LB 아가 플레이트에 중층하여 방치한 후 35℃에서 24시간 배양하였다. 배양한 각 플레이트에서 형성된 용균반을 확인한 후, 이를 선택하여 400 μL의 SM 완충액 (NaCl 5.8 g/L; MgSO47H2O 2 g/L; 1M Tris-HCl(pH 7.5) 50 mL)에 현탁하고, 실온에서 4시간 동안 방치하였다. 상기 박테리오파지액 100 μL를 0.6% LB 탑 아가와 세균 배양액 500 μL와 혼합한 뒤 150 mm 지름의 LB 플레이트에 분주하여 중층한 후 완전히 용균이 일어날 때까지 35℃에서 배양하였다. 배양이 종료된 후, LB 플레이트에 15 mL의 SM 완충액을 가하고 실온에서 4시간 동안 천천히 교반하면서 박테리오파지 용액을 회수한 후 4,000 rpm으로 20분간 원심분리하여 상등액만 취하고 이를 0.2 μm 필터로 여과하여 최종 박테리오파지 용액을 회수하였다. 이렇게 얻어진 최종 박테리오파지의 용균반을 확인한 결과를 도 1에 나타내었다.A soft agar overlay method was used to isolate the bacteriophage from the sample which confirmed the existence of the bacteriophage. A sample of which the bacteriophage was confirmed to be present was diluted appropriately with saline, 100 μL of the sample dilution of each dilution stage was taken, mixed with 150 μL of the bacterial (salmonella gallinarium) culture, and 3 mL of 0.6% LB topa After mixing, the mixture was allowed to stand in a 2% LB agar plate which had been previously prepared, followed by incubation at 35 ° C for 24 hours. After incubation, the supernatant was added to 400 μL of SM buffer (NaCl 5.8 g / L; MgSO 4 7H 2 O 2 g / L; 1M Tris-HCl (pH 7.5) And allowed to stand at room temperature for 4 hours. 100 .mu.L of the bacteriophage solution was mixed with 500 .mu.L of a 0.6% LB top agar and bacterial culture, and then the mixture was divided into 150-mm-diameter LB plates and cultured at 35.degree. C. until complete lysis. After incubation, 15 mL of SM buffer was added to the LB plate, and the bacteriophage solution was recovered while slowly stirring at room temperature for 4 hours. Then, the supernatant was centrifuged at 4,000 rpm for 20 minutes to filter out the supernatant. The solution was recovered. FIG. 1 shows the result of checking the thus obtained final bacteria bacterium.

도 1에 나타낸 바와 같이, 2-3 mm의 크기를 가지는 용균반을 확인함으로써, 상기 박테리오파지가 살모넬라 갈리나륨에 특이적인 용균능을 갖는 박테리오파지임을 확인하였다.As shown in Fig. 1, it was confirmed that the bacteriophage was a bacteriophage having a solubilizing capacity specific to Salmonella gallinarium, by confirming a frying pan having a size of 2-3 mm.

1.2 박테리오파지의 대량 배양 및 정제1.2 Bulk culture and purification of bacteriophages

상기 실시예 1.1에서 확인한 살모넬라 갈리나륨 특이적 박테리오파지를 대량 배양하기 위하여, 1.1에서 회수한 최종 박테리오파지 배양액을 1.0x107 PFU/mL로 희석한 후 전배양된 살모넬라 갈리나륨 1.0x109 CFU/mL과 혼합하고 MOI(Multiplicity of infection)를 0.01이 되도록 하여 35℃에서 120 rpm으로 6시간 동안 배양하였다. 배양이 종료된 후 배양액 전량을 6,000 rpm으로 30분간 원심분리하여 상등액을 수득하였고, 이를 0.2 μm 필터로 여과하여 최종 박테리오파지 배양액을 회수하였다. 분리된 박테리오파지를 "박테리오파지 SG1(Bacteriophage SG1)"로 명명하고, 2016년 10월 21일에 한국미생물보존센터 (Korean Culture Center of Microorganisms, 서울, 한국)에 기탁하고, 수탁번호 KFCC11698P를 부여받았다.In order to mass-culture Salmonella Galiumium-specific bacteriophage identified in Example 1.1 above, the final bacteriophage culture recovered at 1.1 was diluted to 1.0 x 10 7 PFU / mL and mixed with 1.0 x 10 9 CFU / mL of pre-cultured salmonella gallinarum And MOI (multiplicity of infection) of 0.01 was set at 35 DEG C and 120 rpm for 6 hours. After the culture was completed, the whole culture was centrifuged at 6,000 rpm for 30 minutes to obtain a supernatant, which was then filtered with a 0.2 μm filter to recover the final bacteriophage culture. The isolated bacteriophage was named "Bacteriophage SG1" and deposited with the Korean Culture Center of Microorganisms (Seoul, Korea) on Oct. 21, 2016 and received the accession number KFCC11698P.

실시예Example 2: 박테리오파지 SG1의 전체 유전자 분석 2: Whole gene analysis of bacteriophage SG1

박테리오파지 SG1의 전체 유전자를 분석하기 위해, 박테리오파지 SG1 배양액에 20 mM EDTA, 50 μg/mL의 프로테나아제 K, 0.5% (w/v) SDS를 가한 후, 50℃에서 1시간 동안 정치하였다. 동량의 페놀-클로로포름-이소프로필 알코올 (25:24:1)과 혼합한 후 실온에서 12,000 rpm으로 10분간 원심분리하여 상등액을 회수하였다. 회수된 상등액을 동일 부피의 페놀-클로로포름-이소프로필 알코올 (25:24:1)과 혼합하여 실온에서 12,000 rpm으로 10분간 원심분리한 후 상등액을 회수하고, 상기 상등액에 3M 소듐 아세테이트를 전체 부피의 10%(v/v)가 되도록 가한 후 혼합하였다. 여기에 2배 부피의 차가운 95% 에탄올을 가하여 혼합한 뒤 -20℃에서 1시간 동안 정치하였다. 반응이 끝난 후 0℃에서 10분간 12,000 rpm으로 원심분리하여 침전물을 획득하였고, 차가운 70% 에탄올로 2회 세척한 뒤 에탄올을 완전히 제거하여 DNA 펠렛을 회수하였다. 회수한 펠렛을 최종 부피가 50 μL이 되도록 TE 완충액 (Tris-EDTA, pH8.0)에 용해시킨 후 DNA 농도를 측정하였다. 전체 유전자 분석을 위해 HiSeq2000(Illumina, USA)을 이용하여 유전자 시퀀싱을 시행하였다 (마크로젠, 한국). 유전자 시퀀싱 분석을 수행한 결과, 박테리오파지 SG1의 전체 유전자의 크기는 169,805 bp 이며, GC함량이 36%, 전체 ORFs의 수는 269개임을 확인하였다. 상기 분석한 박테리오파지 SG1의 전체 유전자 서열을 서열번호 1로 나타내었다.In order to analyze the entire gene of bacteriophage SG1, 20 mM EDTA, 50 μg / mL proteinase K and 0.5% (w / v) SDS were added to the bacteriophage SG1 culture and left at 50 ° C. for 1 hour. The mixture was mixed with an equal amount of phenol-chloroform-isopropyl alcohol (25: 24: 1) and centrifuged at 12,000 rpm for 10 minutes at room temperature to recover the supernatant. The recovered supernatant was mixed with an equal volume of phenol-chloroform-isopropyl alcohol (25: 24: 1) and centrifuged at 12,000 rpm for 10 minutes at room temperature. The supernatant was recovered and 3M sodium acetate was added to the supernatant in a total volume 10% (v / v). The mixture was mixed with 2 volumes of cold 95% ethanol, and the mixture was allowed to stand at -20 DEG C for 1 hour. After the reaction was completed, the precipitate was collected by centrifugation at 12,000 rpm for 10 minutes at 0 ° C., washed twice with cold 70% ethanol, and then the ethanol was completely removed to recover the DNA pellet. The recovered pellet was dissolved in TE buffer (Tris-EDTA, pH 8.0) to a final volume of 50 μL, and the DNA concentration was measured. Genetic sequencing was performed using HiSeq2000 (Illumina, USA) for whole gene analysis (Macrogen, Korea). As a result of gene sequencing analysis, it was confirmed that the total gene size of bacteriophage SG1 was 169,805 bp, the GC content was 36%, and the total ORFs were 269. The entire gene sequence of the bacteriophage SG1 analyzed above is shown in SEQ ID NO: 1.

실시예Example 3: 박테리오파지 SG1의 형태학적 특성 3: Morphological characteristics of bacteriophage SG1

박테리오파지 SG1의 형태학적 특성을 알아보기 위해, 배양액을 0.01% 젤라틴 용액에 희석하여 2.5% 글루타르알데하이드(glutaraldehyde) 용액으로 고정하였다. 이를 carbon-coated mica plate(ca. 2.5 x 2.5 mm)에 적가한 후, 10분간 적응시켜 멸균증류수로 세척하였다. 이를 구리 격자(copper grid)에 끼워 2% 우라닐 아세테이트(Uranyl acetate)에서 30-60초간 염색하고 건조시킨 후, 투과전자현미경 (Tecnai G2 Spirit Twin, Bio-Transmission electron microscope, 120 kV, 120,000~400,000)으로 관찰하였다. 그 결과를 도 2에 나타내었다.To determine the morphological characteristics of bacteriophage SG1, the culture was diluted with 0.01% gelatin solution and fixed with 2.5% glutaraldehyde solution. The mixture was added dropwise to a carbon-coated mica plate (ca. 2.5 x 2.5 mm), and the mixture was adapted for 10 minutes and washed with sterile distilled water. The resultant was stained with 2% Uranyl acetate for 30-60 seconds, dried, and then observed with a transmission electron microscope (Tecnai G2 Spirit Twin, Bio-Transmission electron microscope, 120 kV, 120,000-400,000 ). The results are shown in Fig.

도 2에 나타낸 바와 같이, 박테리오파지 SG1은 210-230 nm의 크기로, 정이십면체의 머리를 가지며 수축성의 꼬리를 가지는 형태인 마이오비리대(Myoviridae)에 속함을 확인하였다.As shown in Fig. 2, the bacteriophage SG1 has a size of 210-230 nm, and it belongs to Myoviridae, which has a truncated dichroic head and a contractile tail.

실시예Example 4: 박테리오파지 SG1의 단백질 패턴 분석 4: Protein pattern analysis of bacteriophage SG1

박테리오파지 SG1의 단백질 패턴을 분석하기 위해, 1.0x1010 PFU/mL로 준비된 박테리오파지 SG1 40 μL를 10 μL의 5X 로딩 완충액과 혼합하고, 10분간 끓인 다음 12.5% SDS-PAGE를 수행하였다. SDS-PAGE 수행 후 단백질 전기영동 결과를 도 3에 나타내었다.To analyze the protein pattern of bacteriophage SG1, 40 μL of bacteriophage SG1 prepared to 1.0 × 10 10 PFU / mL was mixed with 10 μL of 5X loading buffer, boiled for 10 minutes, and then subjected to 12.5% SDS-PAGE. The results of SDS-PAGE and protein electrophoresis are shown in FIG.

도 3에 나타낸 바와 같이, 박테리오파지 SG1은 75 kDa, 58 kDa, 50 kDa, 32 kDa, 25 kDa, 그리고 19 kDa 크기의 주요 단백질을 가지는 것을 확인하였다.As shown in FIG. 3, bacteriophage SG1 has major proteins of 75 kDa, 58 kDa, 50 kDa, 32 kDa, 25 kDa and 19 kDa in size.

실시예Example 5: 박테리오파지 SG1의 다양한 세균에 대한 감염성 조사 5: Investigation of infectivity of bacteriophage SG1 against various bacteria

박테리오파지 SG1의 다양한 세균에 대한 감염성을 조사하였다. The infectivity of bacteriophage SG1 against various bacteria was investigated.

우선, 박테리오파지 SG1의 살모넬라 갈리나륨에 대한 용균 활성을 확인하기 위하여, ㈜옵티팜에서 분리하여 보유하고 있는 살모넬라 갈리나륨 균주를 대상으로 소프트 아가 오버레이법을 수행하였다. 그 결과를 표 1에 나타내었다.First, to confirm the lytic activity of bacteriophage SG1 against Salmonella gallinarium, a soft agar overlay method was performed on Salmonella gallinarium strains isolated from Opti Pharm. The results are shown in Table 1.

대상세균명Target bacteria name 대상 세균수Number of target bacteria 용균 활성이 확인된 수Number of confirmed lytic activity 용균 활성이 확인되지 않은 수Number of unconfirmed lytic activities 감수성 비율Susceptibility ratio Salmonella Gallinarum Salmonella Gallinarum 15 균주15 strains 15 균주15 strains 0 균주0 strains 100%100%

상기 표 1에 나타낸 바와 같이, 본 발명의 박테리오파지 SG1은 살모넬라 갈리나륨 15 균주 모두에 대해 감수성이 있는 것을 확인하였으며, 이를 통해 살모넬라 갈리나륨에 대한 용균활성이 탁월함을 확인하였다.As shown in Table 1, the bacteriophage SG1 of the present invention was found to be susceptible to all 15 strains of Salmonella gallinarum, and thus it was confirmed that the lytic activity of Salmonella gallinarium was excellent.

또한, 박테리오파지 SG1이 다른 살모넬라 균주에 대하여 용균활성을 나타내는지 확인하기 위하여 ㈜옵티팜에서 분리하여 보유하고 있는 균주와 한국미생물보존센터 등에서 분양받은 살모넬라 균주를 대상으로 소프트 아가 오버레이법을 통해서 감염성을 확인하였다. 그 결과를 표 2에 나타내었다.In order to confirm whether bacteriophage SG1 exhibits lytic activity against other Salmonella strains, Salmonella strains isolated from OptiParm Co., Ltd. and Korea Microorganism Conservation Center were infected with soft agar overlay method Respectively. The results are shown in Table 2.

Figure 112017123862644-pat00001
Figure 112017123862644-pat00001

(+; 용균활성 있음, +/-; 약한 용균활성 있음, -; 용균활성 없음)(+; With lytic activity, +/-; with weak lytic activity, -; no lytic activity)

상기 표 2에 나타낸 바와 같이, 본 발명의 박테리오파지 SG1은 살모넬라 갈리나륨 외에도, 살모넬라 플로럼 및 살모넬라 콜레라수이스에 대해 용균 활성을 나타내며, 살모넬라 티피뮤리움 및 살모넬라 엔테리티디스에 대해서도 약한 용균활성을 나타냄을 확인하였다. As shown in Table 2, the bacteriophage SG1 of the present invention exhibits a lytic activity against Salmonella florum and Salmonella cholera strains in addition to gallinella gallinarium, and exhibits weak lytic activity against Salmonella typhimurium and Salmonella enteritidis Respectively.

다음으로, 박테리오파지 SG1이 살모넬라 외의 다른 세균에 대해서 용균활성을 나타내는지 확인하기 위하여 ㈜옵티팜에서 분리하여 보유하고 있는 균주와 한국미생물보존센터 등에서 분양받은 균주를 대상으로 소프트 아가 오버레이법을 통해서 감염성을 확인하였다. 그 결과를 표 3에 나타내었다.Next, in order to confirm whether bacteriophage SG1 exhibits lytic activity against bacteria other than Salmonella, a strain isolated from OptiParm and a strain distributed in Korea Microorganism Conservation Center were infected through a soft agar overlay method Respectively. The results are shown in Table 3.

Figure 112017123862644-pat00002
Figure 112017123862644-pat00002

표 3에 나타낸 바와 같이, 본 발명의 박테리오파지 SG1은 Escherichia coli, Bacillus cereus , Lactobacillus plantarum 등 살모넬라균이 아닌 다른 속의 세균에 대해서는 용균활성이 없는 것을 확인하였다.As shown in Table 3, the bacteriophage SG1 of the present invention is Escherichia It was confirmed that there was no lytic activity for bacteria other than Salmonella such as coli, Bacillus cereus , and Lactobacillus plantarum .

따라서, 본 발명의 박테리오파지 SG1은 살모넬라균에 특이적으로 용균활성을 나타내는 박테리오파지임을 확인하였다.Therefore, it was confirmed that the bacteriophage SG1 of the present invention is a bacteriophage exhibiting a lytic activity specifically for Salmonella.

실시예Example 6: 박테리오파지 SG1의 pH 안정성 조사 6: Investigation of pH stability of bacteriophage SG1

박테리오파지 SG1의 pH에 대한 안정성을 확인하기 위하여, 다양한 pH 범위(pH2, 3, 4, 5, 6, 7, 8, 9, 10, 11)에서 박테리오파지의 수를 측정하였다. 소듐 아세테이트 완충액, 소듐 포스페이트 완충액, Tris-HCl을 이용하여 각각의 pH에 맞게 조제한 후 990 μL로 분주하여 준비하였다. 박테리오파지 SG1 배양액을 1.0x108 PFU/mL가 되도록 준비한 다음 배양액을 10 μL씩 취하여 pH에 맞게 조제한 각각의 완충액에 첨가하여 2시간 동안 상온에서 방치하였다. 방치 후 각 반응액을 단계희석하여 소프트 아가 오버레이법에 의해 타이터(titer) 측정을 수행한 결과를 도 4에 나타내었다.The number of bacteriophages was measured in various pH ranges (pH 2, 3, 4, 5, 6, 7, 8, 9, 10, 11) in order to confirm the pH stability of bacteriophage SG1. Sodium acetate buffer, sodium phosphate buffer, and Tris-HCl, and the mixture was divided into 990 μL. The bacteriophage SG1 culture was prepared to have a concentration of 1.0 × 10 8 PFU / mL. Then, 10 μL of the culture solution was added to each buffer prepared for pH, and the mixture was allowed to stand at room temperature for 2 hours. After leaving the solution, each reaction solution was diluted stepwise, and a titer measurement was performed by a soft agar overlay method. The result is shown in FIG.

도 4에 나타낸 바와 같이, 본 발명의 박테리오파지 SG1은 pH3-11의 범위에서 2시간 동안 안정한 것을 확인하였다. 이를 통해 박테리오파지 SG1은 pH 안정성이 우수한 박테리오파지임을 알 수 있다.As shown in Fig. 4, it was confirmed that the bacteriophage SG1 of the present invention was stable for 2 hours in the range of pH 3-11. This indicates that bacteriophage SG1 is a bacteriophage having excellent pH stability.

실시예Example 7: 박테리오파지 SG1의 열 안정성 조사 7: Investigation of thermal stability of bacteriophage SG1

박테리오파지 SG1의 열 안정성을 확인하기 위하여, 40℃, 50℃, 60℃, 및 70℃ 등 다양한 온도 범위에서 일정 시간 방치 후 박테리오파지의 수를 측정하였다. 보다 구체적으로, 박테리오파지 SG1 배양액을 1.0x107 PFU/mL가 되도록 희석한 후 배양액 5 mL을 멸균된 튜브에 분주하고 30분, 1시간 및 2시간 동안 각 온도에서 방치하였다. 방치 후 각 반응액을 단계희석하여 소프트 아가 오버레이법에 의한 타이터 측정을 수행한 결과를 도 5에 나타내었다.In order to confirm the thermal stability of bacteriophage SG1, the number of bacteriophages was measured after standing at various temperature ranges such as 40 ° C, 50 ° C, 60 ° C, and 70 ° C for a certain time. More specifically, the culture of bacteriophage SG1 was diluted to 1.0 × 10 7 PFU / mL, and 5 mL of the culture was dispensed into sterilized tubes and left at the respective temperatures for 30 minutes, 1 hour, and 2 hours. After leaving the solution, each reaction solution was diluted stepwise and the titer was measured by soft agar overlay method. The result is shown in Fig.

도 5에 나타낸 바와 같이, 본 발명의 박테리오파지 SG1은 40-70℃의 범위에서 안정한 것을 확인하였다. 이를 통해 박테리오파지 SG1은 내열성이 우수한 박테리오파지임을 알 수 있다.As shown in Fig. 5, it was confirmed that the bacteriophage SG1 of the present invention was stable in the range of 40-70 占 폚. As a result, bacteriophage SG1 is a bacteriophage having excellent heat resistance.

상기 실험으로부터 박테리오파지 SG1은 다양한 살모넬라균에 대한 특이성이 매우 높고, 살모넬라균에 감염하여 살모넬라균 내에서 증식함으로써 용균 활성이 우수하고 물리화학적 자극에 강하다는 장점을 가지고 있음을 확인하였다. 또한 본 발명의 박테리오파지 SG1은 사람, 동물, 식물 등 세균 외의 다른 숙주에는 감염되지 않으므로, 항생제의 오남용으로 인한 항생제 내성균의 문제점, 식품 내의 항생제의 잔류 문제, 광범위한 숙주범위의 문제점을 해결할 수 있는 장점이 있다. 따라서, 본 발명의 박테리오파지 SG1은 살모넬라균에 의한 감염성 질병의 예방 또는 치료, 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제, 또는 세척제 분야에서 다양하게 사용될 수 있다.From the above experiment, it was confirmed that bacteriophage SG1 has high specificity to various Salmonella strains, and has an advantage of being excellent in lytic activity and strong against physicochemical stimulation by propagating in salmonella bacteria by infecting Salmonella. In addition, since the bacteriophage SG1 of the present invention is not infected by any host other than bacteria such as humans, animals and plants, it can solve problems of antibiotic resistant bacteria caused by abuse of antibiotics, residual antibiotics in food, have. Accordingly, the bacteriophage SG1 of the present invention can be variously used in the field of preventing or treating infectious diseases caused by Salmonella, antibiotic composition, composition for feed addition, feed, disinfectant, or detergent.

비록 본 발명이 상기에 언급된 바람직한 실시예로서 설명되었으나, 발명의 요지와 범위로부터 벗어남이 없이 다양한 수정이나 변형을 하는 것이 가능하다. 또한 첨부된 청구 범위는 본 발명의 요지에 속하는 이러한 수정이나 변형을 포함한다.Although the present invention has been described in terms of the preferred embodiments mentioned above, it is possible to make various modifications and variations without departing from the spirit and scope of the invention. It is also to be understood that the appended claims are intended to cover such modifications and changes as fall within the scope of the invention.

이하 본 발명의 박테리오파지 SG1을 포함하는 감염성 질병의 예방 또는 치료용 약학적 조성물의 제제예를 설명하나, 본 발명을 한정하고자 함이 아니고 단지 이를 구체적으로 설명하고자 함이다.Hereinafter, formulation examples of pharmaceutical compositions for preventing or treating infectious diseases including bacteriophage SG1 of the present invention will be described, but the present invention is not intended to be limited thereto but is specifically described.

제제예Formulation example 1: 의약품의 제조 1: Manufacture of medicines

1.1 주사제의 제조1.1 Manufacture of Injection

박테리오파지 SG1 1 × 106 PFU/mLBacteriophage SG1 1 x 10 6 PFU / mL

주사용 멸균 증류수 적량Sterile sterilized water for injection

pH 조절제 적량pH adjuster

통상의 주사제의 제조방법에 따라 1앰플당(2 mL) 상기의 성분 함량으로 제조한다.(2 mL) per 1 ampoule in accordance with the usual injection preparation method.

1.2 1.2 액제의Liquid 제조 Produce

박테리오파지 SG1 1 × 106 PFU/mLBacteriophage SG1 1 x 10 6 PFU / mL

설탕 20 g20 g of sugar

이성화당 20 g20 g per isomer

레몬향 적량Lemon incense quantity

정제수를 가하여 전체 1,000 mL로 맞추었다. 통상의 액제의 제조방법에 따라 상기의 성분을 혼합한 다음, 갈색병에 충전하고 멸균시켜 액제를 제조한다.Purified water was added and the total volume was adjusted to 1,000 mL. The above components are mixed according to a usual method for producing a liquid agent, and then filled in a brown bottle and sterilized to prepare a liquid agent.

1.3 정제의 제조1.3 Manufacture of tablets

박테리오파지 SG1 1 × 106 PFU/mLBacteriophage SG1 1 x 10 6 PFU / mL

옥수수전분 100 mgCorn starch 100 mg

유당 100 mgLactose 100 mg

스테아린산 마그네슘 2 mgMagnesium stearate 2 mg

상기의 성분들을 혼합한 후 통상의 정제의 제조방법에 따라서 타정하여 정제를 제조한다.After mixing the above components, tablets are prepared by tableting according to the usual preparation method of tablets.

한국미생물보존센터(국내)Korea Microorganism Conservation Center (Domestic) KFCC11698PKFCC11698P 2016102120161021

SEQUENCE LISTING <110> Optipharm.CO.,LTD <120> Novel Salmonella specific bacteriophage SG1 and antibacterial composition comprising the same <130> 1-40P-1 <150> 10-2016-0177916 <151> 2016-12-23 <160> 1 <170> PatentIn version 3.2 <210> 1 <211> 169805 <212> DNA <213> Direct input <400> 1 accgtcgtat gaatatcctt cacaatgctc aactgctaat tgatatgaat ctatttcaat 60 atcacgtgct aatttaatga ttttttcaaa ctgttcgcgt gttagcatac ttacactctc 120 gtattatgat tgataatttc atcaagaaac atatctaacg cttctacagc attatcaact 180 ttagcttcaa attcttcaat acctgataag gcaaagttaa tgcgttcctc atctgcttta 240 cgaattaaag ctatcaattc cttaatttta tccgcttgtt cgatactaat cattattcca 300 ccacatatga aagagagaat attgcacacg ccatgtgaat tgcaacttca tcacacatat 360 tataacgttt cttaagaagt tctacaagtt cttcactagt gacttcatcc atgtcgacga 420 aaaaatcacc attaatgatg acgtagatat ttccttcttg attaagtgct tcaattttca 480 tgatgttctc ctctttatcc gatggttgta tagtaccatg gctcaaacgg aaagtaaacc 540 ggtaaaatga aaaaagtctc ccgaaggaga ctaatgttat tcgagggaaa gaagatactt 600 actctggtaa aacattccag taatatcatc tatcgtgctt tggatggctg gaggcatttc 660 tttataaatg ctgttagatt ggtctagtat gcgatcaatc attttaattg tgtcggtagg 720 aagtttacta gcatctggaa ttgaaggtgt gtattttcta ccagaatacc ccaaatattg 780 ctcaccaaat ttatcaatca aatctggcaa ctcggagaaa ataaaatcgt atgctttgtg 840 tctagcataa tttttagttt caaaatgtgc agaatgaaaa taagcttgtg cagccattaa 900 taaacctaag tattcatctg cctttgaagg ttttccactt tgtgaaaagt cgctgaattt 960 cattcagtct ccaatttaat gttcataatt ctagcgtatg attgtgccat ctccgcgcct 1020 cgttctatac attcaaaatc agaagagcac gggtcatttt tataggtcgt tctcataaaa 1080 ctatagaatt gttcagacga ttctacgctt ttattttcaa aaagcatata aacgtgccta 1140 ataccagatt ccataaattt atcaaaatga ggatcgacat tcgcttcaat tggtggagat 1200 aaaacaaatg acaatcctag catggcaaat agtgccgttg cttttaaggc cataaaggcc 1260 tcctatcatt tttgccctgt atttacttta tgccgatgca cggccttaac tttatcaagg 1320 tatttttcaa aatttcgcaa tctagtatag tctgccggag attggttgag tgatacttct 1380 cgacgcaaag ctgaaatgat atttccaact tccctacgaa tttcatctaa ttgaagaaca 1440 gtaagattgc gaagttgctt ttcagttaat tgtagcatat ataccccttt agttagataa 1500 acctatttat aacttttgca ctaaccgagc tttttagtta attcattcca atgttttcta 1560 cacaaagaaa cataaatttc atcaccaata cagatttgat taccttcttt aactggtgtt 1620 ccatcttcca ttaatcgagc tgtcataata gcttttttac cacaatgaca aactgccttt 1680 agttcaataa gtttatctgc aatcgccaaa agttctttag aaccttcaaa taattttcca 1740 gcgaaatcag tccttagccc ataagccata acaggaacat tatatgtatc aacaattcga 1800 cttaattgat gcacctgttc agtttttaaa aactgagctt catctacaaa tacacaatga 1860 atatcttttt gtgcttcagc ccatttatag aactcaaaaa tatccatatc atccgtaata 1920 atattcgctt cctgcttaat tccaatgcga gaaacgactt cacagacaga atcgcgagta 1980 tcaatagcag gcttaagaac taatacaccc attccgcgtt ctttataatt atgtgcagca 2040 gtcaaaagag aagcagattt tccagcattc attgctgcat aagtaaaaat taaactcgcc 2100 atcttagtcc ttagttaaat tttctaaata tgtttctaaa tcattttcag ctttatcgat 2160 agattttact aattcgtaat atgtttcggc atctccatat tcagaagata tttcaaaaga 2220 caaatccttt tctaaactaa taatttcacc aactaaaaat aatatttcgt tcttttgttc 2280 gcgagtaatc ataaggaatt tatataatta ataagttctt gttctttatt atcgaattct 2340 ttagaaagtt cttcgtattc gtcagtatta aaaggaccgc attcattaca aactttttcc 2400 aattcactat ttttatccat aacttcgtgg ataagagaaa agagtttgtc tttttgttct 2460 ttgcttaggc tcatatatta atttccagaa gttttaaaat aattcgcttt tgcttaaata 2520 tttccatagt taaatgatca gtatcttttt ggccaattcc aatggcaaaa cctttattag 2580 cagcgagttc aattaaatta tcaagttcac gtgacacttc atattgtaac tcagaactat 2640 tcatttcggt ttaccttctt taacgaaatc tggataagga taaaatcccg aataaaatcc 2700 ttcaccttta tgattgatgc atcctttatt agaacaatag caccaataat cgaaatcaca 2760 agccatttca tcgttgcata aagcaaaaac aactggccat ttacactttt cacaatgggc 2820 atttttaaga atactagttt ggctcataac catgtcacct ttaagcagta ttcttctaca 2880 tgctgtttac gacctttctt atcaataaag gtatattcaa cgaatgttcc aatgtagtct 2940 ttatctacat catgcggact attaattgga catttagtac ggcaaatgcg ttcccattga 3000 cgaataatta ctgccttatt ctttgggtca tatggatgtg gataatgtat attcataata 3060 atggttccca atcaacaatc acaatttcta atttagagga atatgtatct aaaatcccct 3120 caataatatc ccagttccct ttacctatgc ctgcaccaat cctaggcata tagattgtag 3180 gtttaatcag tttattttca ccaaactcat ttaattctaa catacaattc attaaagcga 3240 aatactcaaa atttggcccc ggttgaaatt gagtataaag attaaagcag taagctttat 3300 gagtcctaaa gtatttttca tagactgagt aagaaccaag tttagttaca tcaccccatt 3360 cagtctgtaa tttatcagct tccaaaattt tagggaaagc tttggttaat tgacctgcga 3420 ctccagcttt catcgtatga aaacaattgc atccatgcgc aatattttta ccttcagcga 3480 aaagggcgac aatatcgccc ttgatatatt ttacaatcat ttagtactca atcctcgatt 3540 ataagaatct accaaacggt caaccattga atgacaagcg gctttatctt tctcctccgc 3600 aactgaacat tctaaggtat tccacttttt agcatatcgt tttaataatg tatcgttttt 3660 gtatctgctt gatttatctc tttctccatc tttatatgca tatattaatt tctgcgcaaa 3720 ttcagcttgg catgctttat ttttcccaca ataatctgcc gcagtgcgat ttacatattc 3780 tctaatttca gtatatgatg tatctgctaa cgcagaagca gaaaatgaaa ttaatcctat 3840 acataaaacc aaaattttag tcatttacta tttccaaaag tttattattt ttaaggtaat 3900 tagccttttc taggacttca gaagcatatt tagaaccagc tttaacattc catcccgaat 3960 tataagagga tattgctttt cttatatctc ccttgtgtat atttaaccaa taagaaagtt 4020 caatgtacgc ccaggaagct gaattggacc gtttattcaa cattcttttt atttcagcat 4080 cggtcatatt ataaccaagt tccttaactc ttgctcgcat agtaggcaaa taattttgga 4140 acattccgta ggcgtgatgc tttggtttag attttaaatt aactccgcca gagctttctt 4200 gccataaaat agcagccatt atatgaccta atccgctctt gtggatattt ttatgtgttt 4260 tatattttcc atccttagaa aattgttccc cgaattgata cgcgtaacgc atgttatcga 4320 gttggacatt actgaaagta tgctcggagc tatgtgccat cattgaaatg gccaatagac 4380 cagcgagtag tgcttttctc atgcttacct cattgagttt taattactgc tttagaagcc 4440 tttcctggta aacgacgact gttaataatt gccatcctac attgaagtga cgggtctttg 4500 aacttcgcgt taggtttaca aactgtaaat ccaagccaaa gatttccatc tgtgatttct 4560 agacgtccag gacgatattc aaccccatca ataaaatcct cgtcaatgtc aggacgcgga 4620 ggcatactca ggaattcatt aacttctaaa acatggtctt ttattttatg gaataattca 4680 aaaacatatg tctcatcaat ctcccgttga attgcgcgat caagaagatg ttgagaatat 4740 tttagatgaa acgatgagac tcctgctgct tttgatgcct cacgaatctc attgttaatt 4800 tgacgaaact ccgactcaaa gtgacgacga agcttatttc gacggataaa aacttctgta 4860 ttgatagtca tgttattctc ctcttaactg atagaaaaat tataccacag tcaagaggaa 4920 aagtaaacag ttattcttta aatctaatca atttattcat agactttgaa acatctgcac 4980 gaacctcatg tagatttttg agctgttcaa gacgctgctc atagtaagca atttcatctt 5040 cttcgagaca gtcctgtgaa tcttctttaa gataacgtgc atagtcctgg aaagcgttac 5100 gaactacttc ctggaagtca tcaagacttt gaattttctt aggagcaaca gatacacgac 5160 gaggggcagt ataatactca taaccaaacc ctgcgcttaa ttgagccatt agtatttttc 5220 ctctggttgg aacactgcac gacaagccca catactggct tctttgagtt tcgttttagc 5280 aatagttaac tgatcgagac tttcagcata attcttcgcg aattcacagt cttcacaatt 5340 atctagcgct tcccagaatt catcatataa agcatcaaag ataagtccta aacgaacttc 5400 agcgtctttg atagcattca ctttactgat tttatcgtca gtatgtggct tataaccttt 5460 aatgtcttca atcatatttg acttcctcac cagtacataa atcatattca actaaacgaa 5520 taggttcatg aatgccatat ccttgaacag aaatttctgt cgtaggataa attccatcaa 5580 tatcacccat ggtccacgct tcattaaatt gctgttcgcc tgaattacta aaccactcgg 5640 cgaaagcatt tagcacatct tcagaacctt caataattat ctttgccatt acaaactctc 5700 agtaaaggta cgagcaataa cgtcgcgctg ctgttccgga gtcagagagt taaagcgaac 5760 tgcataaccg gatacacgga tggtcaactg cggatatttt tccggatgct taactgcatc 5820 ttccagagtt tcacgacgca gaacgttaac gttcaggtgt tgaccacctt caattttaac 5880 tgtaggctgt gattcaattt caatttcacg ggtatgcaaa ccgtagaaaa tttctgggtc 5940 tacaaaagag tcctctttaa aagttttaga gacaataatt cttgcttgaa taccgtcttc 6000 aaaataaata gtacctttat gcgtgccttc aagaatttga tatgctttca tataacctct 6060 caattagaaa ataaatttat ccaagattgt tctttaatta aaaatggctc agaatcatat 6120 gccattaaac tttgggtgat tagtccttta aaaggtccat caataaattc catggtaaaa 6180 tatggaattt tattcattaa tcttgcatta ggagcagtgc acaaaactct gcatcctttg 6240 aatacgcctt tttgtaattt gtattgctta ggataaaatt cgctcaagac gttattattt 6300 gccaaaattt caaaatgatt caccaattta tttttaatag tttttggcga aaaataaaga 6360 tattcgaaaa gttgcgtgtc tgtcatcatt gcattccgat tacgaaaaac tgcggacgag 6420 taataccacc aatgcaacaa ttactattgc aacagtggtg cacagtttca atatgaatat 6480 cgtaaatttt atccatatca ggagatttaa caggctcatc gattatatac aaaattcgtg 6540 aaagcgataa acctctgaac ttgctacctc tattaccaac aaaactacgg acagaatcag 6600 taaataaacg gaatcgaata tcatcattag aatagcgtga aaattctttt ttaatgtggc 6660 ccgcagaaat tttagcgtaa gctgaagtat tagaaagaac aataactgtt ccaccgtcat 6720 acaaccaatt agcggcaaaa ttagttactg cagttgattt accggattga cgtccaccat 6780 ctagtcgaag tgtgcaatac tgttttagta agtcttcaaa tggtgggata taatcgtttt 6840 tacaaatttc ttctactcta gcatcagaat ggtgtgtaaa agcattcatc agggatagat 6900 aaggaccagt taaaaatgtt ctcattttgt tctctctagg tttgggccat tccatggcgc 6960 atgaattgtc catttctgta tttacccatt accgcacttg ggctcgacct tattacaggt 7020 tggcgggaat ccctcacaga atcatgaggt ccaggttgtt cccatattat ttgaacgatt 7080 taacgtactg aatagaacct ttactattca cgaaagcgat tttaccattt ttattataca 7140 tggtagcagt acgctgatag ccataagttt gcttaccaga ttgataacca actaatgcaa 7200 aattatcttc acccatttta ttctgtttag cgcgaatgcg ttcatgacca tgtgccataa 7260 gaaccttagc atcaccagtt gcaatggatc gacgagtttt ttcatcttca actgtattaa 7320 caaagtcgtc aaatgaatca aatttagcat gagatttatt atacagtttt ccatctactg 7380 cataattata tccctgtaca tccatctcaa cttctgtacc atcatccaat acagcagtga 7440 ttttctgtcc ttttttaaat ttcaaaagat cagtaaaaga ttcagcaata atttgagaat 7500 taatagctgc ttcagtaata aattcttgat atgttttcat gtgtttcctt taaatgtaaa 7560 tattttaatt ggtaattgtc tattcaagta actgtgaata tactatcaca attctaagag 7620 aaagtaaaca gctttataga tttttatacg cgtcccaagt gccagttcta aacgtagcaa 7680 tgactcgttt tgcgcgatta ggtgtttgat tataccatcg acttttagct aagttaactg 7740 ctgcttcatc ccagcgtttt tgttggagca tacgtaaaga attagtaaat cctgctacgc 7800 cagtttctcc catttggaag accatattaa tcaatgcaca gcggcgaaca gcatcaagag 7860 aatcataaac tggttttaat ttagcatttc tcagaattcc gcgaacagca gcatcaacat 7920 cctgattaaa gagtttttca gcctcatctt ttgtaattac accattgcaa ttacgcccaa 7980 tagctttatc taattcagat ttagcaacat taagtgatgg actttttgta agcaaatgac 8040 caatgccagt agtgtaatag ccttctgtgt ctttatagat tttaagtcta agaccttcat 8100 ctatacgtaa catttcaaat atattcataa tacctcctaa gtatttatag aaggtattta 8160 taaattaaaa gaggttgttc attattcggt aaagtgaagg acccatcaca tattgccact 8220 gagtacgagg aataagagca aaagcgtcca tctctggaat cataacacca tctttatttt 8280 caaaataaga ctcgcaatgg caatttctaa acatctcatg ctctactgga atcgtataat 8340 aaaatagctg taagtcttta ttactagaat atttaaatac acctaggtct tctagaaggt 8400 ctggattata attgctaaaa ccggtctctt ctaagcattc tctttttgca gcttccagtg 8460 cattcaaatc agaactttct acacggccct ttggaatatc ccagcggtgt gccatcattc 8520 caggcttacg agaaccagta acccgaccca taaataaatc tttatcttct gtcataaaga 8580 taataccagc tgataaggtt ttcattttaa tttcctgcat tcagtgataa agttatttaa 8640 attttgagca tatttctttt catcaaaaat cttttgctgt ctgcgtaaac gccatggcat 8700 ttcaatgaac atacgcccat attcctgata atactgctgc tgtaaaaata ttaacaagta 8760 tagttaaaag aacccaatct cctattctgt ccattggatt ttttataaaa aagtaaaata 8820 cgaacgatga tataggaaga ctaatgatat accacagaat aaccttctta tctgtgaacc 8880 aatcggcatt cgttaactta gcgcgaccat tttgaataca cacgaattta tcatctgtta 8940 cagtaaatgg tttagctgct tgatatccca ttctaaactc cctaattaat cgtttctttg 9000 tatcttcgga acaaccattc caatcaactc tatcaactga aatgccatca tccccatcat 9060 ctaaatcata ccagcgagtt tttaaaatca tttaattttc ctgcaatcgc tcacaaactc 9120 tttcattgat tcattttcaa tataagacat gtagctatta tattctttta attgtatttt 9180 gtaatccttt tttctttgcc aatttatttt aaaattatca taatgaaaat ataacattgt 9240 accaaagaat gaaaataatg aaatcgctat agtaaaacga agttcactcc aaacttctat 9300 tatatctatt ataccgctga cgttactacg gatgtttaaa ataagacagt caattaacaa 9360 tccaaaaaga ctacctgcaa gagctgcaaa tgctgatacg gcaagaatta atagtgcctc 9420 tggaaacgaa tatttaactt tatttagttt tggcttttgc atcgtgattc cttaacaaat 9480 ttcataattt catcaaattc atacgcggca agtttaagct gatgttcatt tttaatcttt 9540 ttacactgtg ctttccaatc acgtacacgt ttacgataat gtcttccttg ataccaatat 9600 cctatccaat ttacaggtac taataaaagt ggaactatta atggaagaat tagcattaac 9660 acaagtattt cgccagaatc aatatcagtc ataacatcta aaacacctcc aataatcaat 9720 agaattacaa atgatatgag tataacagga cctattaaca catcagtagg aattatctgg 9780 cgctttaatt catactttaa gggtttactt ggaagataca ttgatggctt tgacatattc 9840 tctacattcc ttaacaaatt tttctagtaa taaatcactt tcaaaattag gattttccac 9900 taatttatca aaaagatcat caacaatatt caagatattt cttttactaa gaatacgttt 9960 attttcatgc ttcgtttcag aatcaactat aagagtaaag aaatatttct ttccctgaaa 10020 ttttactgta gtatcaatat agaataaatt tgacttttgt aagttacgtt taaaccatgc 10080 gtcacttaaa ctataaacac cgagataatc aaaatcgtcg tttaaataac atactgtcca 10140 ttcaggagaa atgaaatcag taaattcaac atcaaaatca cacgtcaatg aatgaattga 10200 ttcaatactg ttaataagta ttccaggacg tattaaagac tttttacctc tggaaaatct 10260 tccagaaaga ctttcattag tttcatatga agaaccccaa taataattac gtccttctgc 10320 catacgttta agagcattta gtaattggtc tggaacatca acttgtcttt ggaattcttc 10380 aaacattgaa ttgaaatcac tttgcatttt cattcctatt tactccaagt aataggggcc 10440 gaagcccctt atcattattt cagagaatta atgtattcct gaacatcggc agaggtagtt 10500 tcaaccccag aaatattacc attaaaggtt tcaactcgag caagggtatc ttcaatatca 10560 accttagtca gtgctgcaat ttcaactaca tcatcagcag tactaattcc aagggcattt 10620 gctgcacgag tttcacggat atattccaat ttaactgcaa gttcttggcg agcatcatct 10680 aactcaacta ctttcttggc gatttcaatt cgcatttcag cataaccgtc agccttagta 10740 gtcaactgtt cagctgttcg acgatatagc aaaccgagtt tagcatgcat tgttacatct 10800 tgaccttcgg aaagaagctt gcgaatttca cgctcttttg attcagcctg tttattcttt 10860 tcaacgataa gttcacgaat acgtttttct tcattaatag atttaacaga agcagttttt 10920 agatctttaa ttttatcaag cagttttgct gctgcggcag tatactgttc ttcaacagat 10980 aaatttttag ccatagcaga accaagttta gtgcgaataa actcaacaat tttcttcagt 11040 gtgttcatag tatttcctta ggttgattaa gatttaaaat ctgtggaaga attatatccc 11100 attatttgag agatgtaaac tatttttaat tttacaaatt cgttcagctt catcgatagc 11160 agcattaata atgcttttag ctataggagt actaatacta gtagctttta cacttaacac 11220 gatttcttta tctttaccag gccaacccca cgatttttca ccatgagtgc ctttaattac 11280 agcagacacc tcaagtgagc atccattatc gcatgttttt acattaacaa cccaagtgtc 11340 acttttctca accggtttat cccagtaaat attaagaata cgtgggacat caaatttagc 11400 agggcaaatc ttaaccgtaa gaccttcgct ttctagccaa ttaataagag ggcgttcata 11460 catgcggcga tgtgggcttt gaactcgaca agctttgtac ccattgcttg cggcttcact 11520 aagctcttct aatacctgct tttgcattat tgataagata tcatcaaaag atttttcgga 11580 agtttcattc agttcggtat aaagagacat aacagtttcc tcaaattata ggctcataat 11640 atctcaatca tgagcctatg taaacttatt tcatattatt aaaatattct tctgcgattt 11700 cgtcgttatc atggtaaact ttagaagaca gtttaacata accttctgct gtgaacatgt 11760 taatcacaac ctttacagta taccactgac catcttcatt acccattact gcgtaagttt 11820 caaacatcgg atggtcagga ccgataactt taatatcatt cactgtacga ccgaaatctt 11880 ctgaaacaca tttcataaag aagttgaaca gttcgccgta attatccatt tcattctcca 11940 agttgttttt ctgtatcagt agttgatagt tgtatagtac catggaagga caaggatgta 12000 aaccgttttg tgaaaaattt tttaaaaagt tttagggaat tctagggcag ggaggggcaa 12060 ttaaaagata ggataatata ttataaaggg tagaaactaa atgatgtcta gagaggcctg 12120 gaaaggccta gataccaaaa agccccaacc ttttggctag ggctaagaat gttatttgat 12180 ttgtttagca gaccaaatgc ggtctttaat aattttttgg atgtcttcaa catactcaag 12240 agagtgagca tgtgggttat ctttgaaact ataagcacga gctagctttt ggccttcagt 12300 tttgattact aaaagctctt taaggatagc ttcatattta gcgataattc ctttaacaat 12360 atttttttct tgtgcagctt taggatctgc tttaggagca ggtttacccg aagcctttgc 12420 aaaagcagcg ccagtagcaa ctagactttt ccaggccata ctaactgcat ttcccgtaaa 12480 tccttctgct ttcatgtcgc gagcaaattg gaatcgtgat tcgtcagaag catctttata 12540 ggaatattta cccgctgcaa tggctgcttt tgcgacagct tgaatttcgg tgctagatgc 12600 ttcatttaac accgcttcat ttaaaaattg agcatatgat ttcatcttat ttcctgtttt 12660 aattcgtgga tttaatatac tactatattt atactaaaaa gccccaacct ttcggtcggg 12720 gctaagcctt gcggcaacct tgtcggggtt ccacctgcta aggcaagtgt ttgtacgaaa 12780 cgccgggatt tgaacccggt tattaagtag ttgacgctac tcaatatttt taaaaggcca 12840 tatctcgacc atatccgaac gttccgtcaa aaacgctact cggcttatgg caaagatatt 12900 tcctcgaatc gataattcgg tgcgccgttt ctgctgtgat gtaagagggc atcaataaac 12960 gtaaagatta ttaacgcaat tccttactca gggaacatca gtccgacgac ttaccggtag 13020 cgacccggtt tcttaatatt cttttaaaga atcaatatat tcacggcgtt tacgccacaa 13080 atcaattgct tcatacgcgg attcagcatt tcgaattagc cggcatttat gtaaagactt 13140 atgattttga tattgtgtag ataacggaat tgtatctaaa aggtctttac gatcaaaata 13200 ttcgtaacca tctaaaccaa atgaacgatt tttgagaaat tgccaatgac catattcgtt 13260 ttcgacataa acataatctg catgctgata aagcaaatta attacacgtt cagaaataac 13320 agtatcatta tgattaaaat agaatgttaa atcatgaact actaaataaa cattaccttt 13380 catattttcc tcacttataa ttggtcgagg cagaaggatt ctaaccttca acctacggat 13440 tagaagtccg ttgctctata caattgagct atgccccgta attaaaattt catttttcga 13500 cctttaaacc atccttctgg aattgggtca gttttcttaa tacgtttaga aactttttca 13560 tctaatgaat gaatccacat cataccaaat tgggaattct tttcgccctg ttggtgttta 13620 tttctggtgt gagattcttt cattttatta atagtttcag gagtatggga cttacccaag 13680 aaagatttag tatttaaaaa tttctctcta tacttaggat tatcccaaag ctgtttaaac 13740 ctttctgaac ccattttacg atatttttct ttaaggtctg ggtcgttctc aaatctggtt 13800 ttaaaagcgg cagccccttt taaggaagct tctttctttt tatccaaata ttctttagtg 13860 tttaaatggt cccatccacc ttcaccacct aatttcaaat tataaacatc agggcgcttt 13920 aaaaactctt cagtcacaat attcttttct gactcaaaca tagaggtttt atcgtcaaag 13980 aactctaata tttctttaga aaaattttct ataccatact tatcttgggc tctttttaat 14040 aatttaccag aacccatata tccatcatct aaattttcgg tagaatgagc gcctatatag 14100 attttattat taattttatt tgttatttta taaatgtaat ggaacataaa tatctcctat 14160 ttctaagagt atttatgttc ccaaaatatg gccctgggtg gaattgaacc accatctggc 14220 gattatgagt cgcttgcttg aaccttccag ctacagggcc ttgatatgct gattgacgga 14280 atcgaaccgc cgacgtcctc attacaagtg aggtgctcta cctactgagc taaatcagca 14340 acggaggcga taggatttga acctatgagt cgccggagcg actgccggtt ttcaagaccg 14400 gtgcattaaa ccactctgcc acgcctccag tctccgtggc aggatttgaa cctacgacat 14460 tctgctccca aagcagacgc tctaccaaac tgagctacac ggagtaaatt aaatttgagc 14520 ggataatgag aatcgaactc acatcatcag attggaagtc tgaggtaatg ccattatacg 14580 atatccgcaa actttggtac gagaagtggg actcgaaccc acaaggaaat cattccgcag 14640 cattttaagt gctgtgcctt taccaatttg gccattctcg cgctgggaat aaaggactcg 14700 aacctttgca tcctggaatc aaaatccagt gccttaccaa cttggctaat tcccaattat 14760 taacaaaggc tcttaagcaa gaacccttga tgatagaggg tattaatcag tgcgatatga 14820 gttaataata acaaataatt cttaaagcat atttaccatt tatgataata catatttacg 14880 atgcattcaa gacccaaagg attcttgaaa atatcatatt caagaggacc tttttctgtt 14940 tcaataaaga aatcaaaatt tactgtatta aatttacggt cttcctttac taatttaact 15000 tgagaagatg aacggtcaat gtaaaccttt tcaacttcaa aacatgttaa aatgccataa 15060 tcatcaatca aggctttagc tgcttcttga tcatatttat atccattttc aatggatgat 15120 actttcgcat aaagaatcat tattaacctt tatcaacaat agtatgtgta tgggcattta 15180 cgatttgcca ccaatcgaaa ctatcgccaa atcgttttga tttattgtct tcaataattt 15240 ggcgtaattc atcttctgtt tcagcatacg caatcaaatc atcatatcca ccgcaaggat 15300 agtaattatc gcctgcgaat aaaagaaaat ttactttaga tgggtttaca taataatgct 15360 ctttaggata tttagttcct ctccaatcag ttacttcaac ataacgataa gaaaatccat 15420 ttttactttc aatccaactc cacgcttcaa aaggagtatt aaaaacttta tcaggtatta 15480 aattaccttc aaaatgagaa ggatttgcat aatccccagc ataaacatag tattcgttaa 15540 tactcacact cattctattc acctttagaa attttatcca taacaatagc tattaaacca 15600 attaaaaatg ctactacaag tgaaaacaca ttttctgctg tagttaataa tccgcatata 15660 aatccaacaa acattgaaaa actaaaagcg gaagcagaaa ttgcaatagc aacatttcga 15720 attaattcac aacgtttcat tttattctcc tcagtagttg atagggtaat agtatcacaa 15780 ctaaaaccct atgtaaacaa ctttgtgaaa tatttattac aaaagatttt tagcaataat 15840 tttgagctga gctactgaaa tatgcttggc tttaaacaaa gcagtttctt cagcaggaga 15900 gataacgatt gtagcaccat cctttttagc agaccaccca tcgcctaggt aaacagtacc 15960 tttgatttct tcgccatcaa ccagactaat cattggttta ccttctcgtc ctttatttgc 16020 tttaataact tcagaagtaa gagtagcttc ggtaatggta gaaaccgggg tagttgtaga 16080 agtaaactct ttgaaagttt tcattttatt ttcctaatta attttgatga gataatagta 16140 tcactacctc atcagcatgt aaacaacttt gtgaaattat tttaaatcat ctgcccaatc 16200 gagtttaaga ggctctttgt attcacgatc taatacgacc ggaatttgta catcaccgct 16260 aaatgataag ggcccaacat tataagacaa tgttatatgc ggtgtgtaat catcaaaatc 16320 atgtgtagca cctagtgccc gcgcatacat gtgtcgacag cgcagatatt cagaatctag 16380 cacaagtaca agagtcgatc catcttgtgt tttccatact tctaaatgtc cagaagaagc 16440 tacttcaaaa cttccgcttg atggaacata cggaacattt actcttgaat aacatatggt 16500 cgaatgaatt ttttctctag gaactggatt aggaacacgt aaagagcgct ggagttcttc 16560 cagcgcatca agtgttaatt ctgaaaactt agctgctaca taaagacccg ttgaaaagtc 16620 tttaaattcc attattcttc atcttttgct tcatcagtag attcagcagt aagattcttg 16680 acagcttcaa cgatttcttc aactttgata gtatcgccag tgatacctac tgcacgagcg 16740 atttcagcca aagttccttg cagaattttg gattcttcca tcagacgagc cgcttggtcc 16800 tgcgtatcaa gaatacgaga cttcagagtt acgatttcag cagacagttt ttgttcaata 16860 gtttgttcag acattatagt acctttagtg tatttttaat tttagaaaaa agttcttcaa 16920 gagaaccatc gtttgtaatt actaaatcgc catcacgaat tggcaatcca gcttctgtaa 16980 tatgtgtatc attggatttt tgaccaggac gaactacatg aattactgta gcacccatcg 17040 ccctagccgc atccatttca tgatcttgac gagtatcagg aacgatataa taatcataac 17100 ctgagttaaa tttatcaaga taatctaaag caaataattt tacccaatac atgcggtcga 17160 agttattaac aatcaaatcc gtacctaggg cttgcatcag acgacggact gaccattgat 17220 cttcaatatt atttataacg tcagcaatct tattaaatgc tacgaaatta actgcgtcat 17280 caaaaacaaa tacgccttta attgggcttt tactattaag atagcaaaat gcttgttcca 17340 taatcgtaat tacttctaat ttagtcagat ttaaattagt ctcacgatca tagtcaattc 17400 cttcaaactc tttacgagtt aagcaaggat agtcagtgtt tgctgcaaat acaccccatg 17460 cataagccaa tgcatcctta ataggaccag caagttgata tttaactgca gaataattat 17520 tcatgataaa atctgcagta gtatcttttc cactacgctt tacaccactt aaaaagatta 17580 gtttcatatg tttctcctca aatttagtta agattataac acatgaaact gaagcattaa 17640 acttctgcta taattttacc atctttttct acttgaaaat acgtataagg aatcgttgct 17700 gtacatacta aagccgggtc tgaatcttcc gtgtagctaa attctacttc agacaggtca 17760 gaaacccaag gcttataaaa atttattgac atcacaattt cagttttact attatctaaa 17820 atgtaaagcg taatgtattc aggacctgtt ttttgggcag tattttcacc tgtaagatag 17880 ttgctagttc ctagcatcca ttcatacatt cctatccacg acttaagttc ttcatcaact 17940 ataaatctca cgatgagtgg atcgtactca aatgtaactc ctggacgctg tgctcggcct 18000 agtccaaacg gcccagtcac ggtatcagta acaggtatcc taattcctgg aataggaact 18060 gactgagcat ttaaagtaaa agcggatgta gtattactat gcggtattga tactacaaag 18120 ttagttgtat ttgcttggtt aaaaatttgt tgcagtgctt gcgacatata ttcctcataa 18180 tgcttcataa atgttggtgg tataatgggt ctaagtccct tccattcaat tccaattaga 18240 acaaacaata gaaaagaatg gaagataata gaattagata tttgaccaga ctttgtttgc 18300 agagaaacgt tttcctttgg agtagaagct ttggagtggc atcaacacaa cgttcgccca 18360 gtctttcggg gcgatttcaa caaggctacc cataatatta ccaggtatat atgccttaat 18420 catttggtct gcacccctaa atcctttcac ttgactccaa tcaattttta atttcgtttt 18480 attagtaata gtaggtgtat tcgaatattg ctttaaaagc tcttctagaa attgctgacg 18540 agctttaggc ggaatatagt gcaagttcaa tccgtacatt aaattatgtt tacctaaacc 18600 aaggtaaatt atcaaaggaa atttatccca gtaaggaaga gtttccttgt gtttagcatc 18660 ataagcaaaa gcatatattc gtcccggctg cgggcgaaca actttatgtc cttttacttg 18720 cttaatagtt tcagcaaacc actttctggt tttattatta attgctgcac cttcattacg 18780 aattttatca cgcaatgttt gcctgaatga atttatcata agcagttgtc tttcttgctt 18840 attgagctta ttcattggtt ttgattcaag attttgaatc ttttcggcag ttttaattcc 18900 tgaagcatat tttgacattg ccgaagtaaa cgtagagtat ttgattcctc tttcttcagc 18960 aaattgcttt cctgtcattc cttttgcttt ggcctttttg tattcaagac ctatctgaat 19020 ccatttcttt tcgtttaatg attgcttaac ctttggaact tggggagtgc tttcattaat 19080 tatttgaaaa atagccatta tgccccctta aagccaagag ctcgtaatcc atcttccgtt 19140 agaattctaa attttattcc acgcttttca gctaaagctt gcgctgcttt ccatttgtca 19200 gtattaacgg aatatgtata aatttcattc ataaatcttt tcttcgctgc agttgttaga 19260 tgtgctggtt taactggtgg ttgtgtttct tttttaggtt ttatttcaat aaaaaattct 19320 tgtccagaag aatctttcat ccaaatatcc atgaagtatc tacgcttttt cccttctgca 19380 ttacaaaaat aaggaattac tgctgtttca ctaccccatg caataatttc tggattttta 19440 tctaaccatt caaaaaagaa tttttcccaa tttgatctat acgtaatttt tttagggtca 19500 cctctatact ttgatatatt tttaggaacc cattttccag aatatgccat tggattctcc 19560 ttataaatag ataatatatt tataaacagg agggcccatg ctctttacat tttttgatcc 19620 gattgaatat gcggccaaaa cggtgaataa aaacgcgccg actattccta tgacagatat 19680 ttttagaaac tataaagact atttcaaacg tgctcttgcg ggataccgct tacgtactta 19740 ttatattaaa ggttcaccac gcccggaaga attagcaaat gctatatatg gaaatccaca 19800 gttgtattgg gttttattga tgtgtaatga taattatgat ccgtattatg gatggattac 19860 ttcacaggaa gctgcttatc aagcatctat acaaaaatac aaaaatgtag gtggagacca 19920 aatagtatat catgtgaatg agaatggtga aaaattttat aatttaatat catacgatga 19980 taatccatat gtttggtatg acaaaggcga taaagctaga aaatatcctc aatatgaagg 20040 agcacttgct gcggtagata cgtatgaagc tgctgttctt gaaaatgaaa aacttcgtca 20100 aataaaaata atagcaaaat cagacatcaa ttcatttatg aacgacctta tacgtataat 20160 ggagaaatct tatggaaatg ataagtaata accttaattg gtttgttggt gttgttgaag 20220 atagaatgga cccattaaaa ttaggtcgtg ttcgtgttcg tgtggttggt ctgcatccac 20280 ctcaaagagc acaaggcgac gtaatgggta ttccaactga taaattacca tggatgtcag 20340 ttattcaacc tataacttct gcagcaatgt ctggaattgg aggctccgtt actggtccgg 20400 tagaaggaac tagagtttat ggtcattttt tagacaaatg gaaaactaac ggaattgtcc 20460 ttggcacata tggtggaata gttcgcgaaa aaccgaatag acttgaagga ttttctgacc 20520 caactgggca gtatcctaga cgtttaggaa atgatactaa cgtactaaac caaggcggag 20580 aagtaggata tgattcgtct tctaacatta tccaagatag caatctagac actgcgataa 20640 atcccgatga tagaccgtta tcagaaattc caactgatga taatccaaat atgtcaatgg 20700 ctgaaatgct tcgccgtgat gaaggattaa gactaaaagt ttattgggat acagaaggat 20760 atccgacaat tggtattggt catcttatca tgaagcagcc agttcgtgat atgaaccaaa 20820 ttaataaagt tttatcaaaa caagttggtc gtgaaattac cggaaatcca ggttctatta 20880 caatggaaga agcggtaact ttatttgagc gtgatttggc tgatatgcaa cgtgacatta 20940 aatcacattc taaagtagga ccagtctggc aagctgtcaa ccgttctcgt caaatggcgt 21000 tagaaaatat ggcatttcag atgggtgttg gtggtgtagc taaatttaac acaatgttaa 21060 ctgctatgtt agccggagat tgggaaaaag catataaagc cggacgtgat tcattgtggt 21120 atcaacaaac aaaaggccgt gcatcccgtg ttaccatgat tattcttaca gggaatttgg 21180 aatcatatgg tgttgaagtg aaaacaccag ctaggtctct atcagcaatg gctgctactg 21240 taactaaatc ttctgaccct gctgatcctc ctattccaaa tgactcgaga attttattca 21300 aagaaccagt ttcttcatat aaaggtgaat atccttatgt gcatacaatg gaaactgaaa 21360 gcggacatat tcaggaattt gatgataccc ctgggcaaga acgatataga ttagttcatc 21420 caactggaac ttatgaagaa gtatcaccgt caggaagaag aacaagaaaa actgttgata 21480 atttgtatga tataacaaat gctgatggta attttttggt agccggtgat aaaaagacta 21540 acgtcggtgg atcagaaatt tattacaaca tggataatcg tttacatcaa atcgatggaa 21600 gcaatacgat atttgttcga ggagatgaaa cgaaaactgt tgaaggtaat ggaactatcc 21660 tagttaaagg taatgttaaa gtagttattc aaggaacagc agatataacc gttgaacagg 21720 aagcatacat aactgttgaa aaagacacga ctgttaatgt taaccaaaac gcagacataa 21780 gtgttaaaaa taaagcaact gttaatgctg aaaatatgga tgtcaacgtt gagcaagatt 21840 taaatttttc agcgacaaat attaatttaa gtgcatctaa tactgttcat atggatggcg 21900 gggttctttc taaagtatca ggtggaaacg tacaggttgg ttaatatgaa ttataacgaa 21960 attgttgatg aattagttga taccatacaa tcagcttgtt caattattcc cgaaggttat 22020 tatagacgag ttaaatggga attatacaat cccaataaag aaatgattca acccgataat 22080 ggggttgaat gggacactga aattattaaa ttagataccc atctttacac cgaaaatcca 22140 tttggtcatt cttctgatac atttactgaa tcatctgatg gagaaaccca aactggtgtt 22200 ttttgtcata aaatcggcgt gtattttcca actcaaactg cgttagaaga ttacgttgaa 22260 caaattggtg caactttact tccaggtaat acttggtatg gtgctgattt atcgaaacgt 22320 gaatttttta aaactgaaat tgaatatgat atgtatcgca ttgaaaatcg cggaggtaca 22380 tggcatcata cgggtcctag aatagatgct aggacaatga tcggtgttaa caatgactat 22440 acaatgtatg ttaactttaa cggtttagga gattatcgaa gagcatattt aaaatattat 22500 gaagataaac catgcacata tgtcggttta acactaaatt taaatataga tacatcaatt 22560 cccggtattc cttattcacc tccatcaatt attggagagc ttccacttaa tgcaatttca 22620 tgcgttaatt ttactgccca atttccatac aatggcttaa catctgcaat tattgaggct 22680 tggaacacct caagagattc atttaaacta tattgggata tgttgcctgg tatgccggca 22740 attagcggaa gtgattttga aaaatatttt aattcggcat atacacattt atctgtagca 22800 atggaagagc ttggaaattc ggcaattgcc atgtgtcaat atgttcagca acaagccttt 22860 atggttttta aaaattctgt ttcacaagtt ctaaatattg tcggtggcgg atgggattta 22920 ttaaaaagtt ttttacctaa aataacaata atgggcatat ctattgatat tgaagattta 22980 tgtacatcaa cagatggtgt tcaaaaattg aaggaaacct ttgaaaattt taatctggaa 23040 gatactatta gttcaattta ttctgcaatg ggttctgcat atgactattc tatagaacgc 23100 gttaaaatgt attcgcggga tttagttgat gcaataacag atttatatga ttgggcctgg 23160 tcaaaattaa tgatggccgg tgtcgcttta tcaaaattat gtgttgattt agcacaaatc 23220 tggagcatgc cgccaattat tccaaatcca gtgtggtctg ttatcacttt agtgaaggaa 23280 atgatgaaac aaattcctcc attagatatg attatgtcag gtaattttcc tggatttact 23340 gcttctgatg tatatcagat ggttatgtct atcgtatctg aaaaaattaa acaagtttat 23400 actgaaatag aatcattaaa aacccaagca ttggatgtat ggaatgaaat taaactaaaa 23460 acacaggaat ataaaaagca aacgattgaa tttaaacaat atttatcagg aatggctgaa 23520 aaggttgaag atgaaataac tatagcaaaa aagaaagcgt tacaagaagc tgaatccgct 23580 ttaaatgttt taaaggataa atataacagt attaaagact taataaaaaa taaacagatt 23640 tctgtgtctg atgtattaga tttagctttg actgaatttc gaaaaattcc attaatttca 23700 caaatggaat cattattatc tttagctgga gcatctatcg atgatataat gaaagtatat 23760 gaaaatagcg ttactaaagc aaaatcatta tatcacgaat tcaccgatgg cgctcggtca 23820 atgaaagatc tatgcaaatc attatacaat caaatttcga ctttatgttt gagtaaggtt 23880 gtgcaatgga ttaataaaat gcttggaata tttggattaa gtattacatt tccaacagta 23940 tcaatatgca ttccatgctt aaaaactcct atgaggaatt aaaatgacaa ctcctgtaaa 24000 ttatcaatta acaagaacag caaatgctat tcccgagata ttcgtcgggg gtacgtttgc 24060 tgaaataaaa caaaacctca ttgaatggct taatggccaa aatgaatttt tggattatga 24120 ttttgaaggc tcaagattaa acgttctgtg cgaccttttg gcttataata cattgtacat 24180 tcagcagttt ggtaatgctg ctgtgtatga aagctttatg cgtactgcta acttacgaag 24240 ttcagttgtt caagctgcac aagataacgg atatttacct acttcaaaat ccgctgcgca 24300 gaccgaaatt atgttaacat gcaccgacgc attgaatagg aattacatta ctattcctcg 24360 tggtactcgc tttttagcat atgcaaaaga tacttctgtt aatccatata acttcgtttc 24420 taccgaagac gttattgcta ttcgtgataa aaataaccaa tattttccgc gtttaaaatt 24480 ggcccaggga cgtatagtaa gaactgaaat catttatgat aaattaacac ctattatcat 24540 ttatgataaa aatattgata gaaaccaggt taaattatat gttgatggag cggaatggat 24600 taactggacg agaaagtcaa tggttcatgc tggttctaca tcaacaattt actacatgcg 24660 tgaaactatt gatggaaata ctgaatttta ttttggtgaa ggtgagattt ccgttaatgc 24720 ggcagaagga gcattgactg ctaattatat tggaggtctt aaacctactc agaactctac 24780 gattgttatt gagtatatca gtactaacgg tgcagatgcg aatggtgcag tcggattttc 24840 atacgcagat acattaacaa atataactgt catcaatatt aatgaaaacc caaacgatga 24900 cccagatttt gttggggcag atggcggcgg tgacccagaa gatattgaac gtattcgcga 24960 attgggtact attaaacgtg aaacccaaca acgctgcgta actgcaaccg actatgatac 25020 attcgtttca gaaagattcg gttctattat tcaagcggtt cagactttca ctgattctac 25080 taaacctggt tatgcattta ttgctgctaa acctaaatca ggactatatt taactactgt 25140 acaacgtgaa gatattaaaa attatctaaa agattataat ttagctccta ttacaccatc 25200 aattatttct cctaattatc tttttgttaa gactaattta aaagtcacat atgctttaaa 25260 taaactacaa gaatccgagc agtggcttga aggtcaaata attgataaaa ttgatcgcta 25320 ttataccgaa gatgtagaaa tttttaactc atctttcgct aaatctaaga tgttgacata 25380 tgtagatgat gcagatcatt ctatcattgg ctcatccgcg acaattcaaa tggtacgtga 25440 agtacaaaac ttctataaaa cgcctgaagc gggtattaaa tacaataatc aaataaaaga 25500 tcgttctatg gaatctaata cgttttcatt taattctgga cgaaaagttg taaatcctga 25560 tactggttta gaagaagatg tattatatga cgttcatata gtatcaacag accgagattc 25620 taaaggaatt ggcaaagtta ttattggtcc atttgcttct ggcgatgtta cagaaaatga 25680 aaacattcag ccatatacag gcaatgattt taataaatta gcaagttccg atggacgtga 25740 caaatactat gttatcggtg aaataaatta tccagctgac atgatttatt ggaatatcgc 25800 taaaattaat ttaacatccg ataaatttga ggttcagact attgagctat attctgatcc 25860 aatagacgat gttattttca cacgcgatgg ttcactgatc gtatttgaaa atgatttacg 25920 tccacaatac ttaactatcg atttggagcc tatatcacaa tgacagtaaa agcaccttca 25980 gtcactagtc tcagaatttc caagttatcc gcaaatcagg tgcaagtacg ctgggatgac 26040 gttggtgcta atttctacta ttttgtagaa atcgctgaga caaaaacaga ctcgggggaa 26100 aatctcccga gtaatcaata cagatgggtt aacttaggat atactgcaaa taacagcttc 26160 ttttttgata atgctaatcc attgacatcg tacattatta gagtagctac cgctgcgcag 26220 gattttgagc agtctgattg gatttatact gaagagtttg aaacttttgc tacaaatgct 26280 tatacatttc aaaacatgat tgaaatgcaa ttagctaata aattcattca ggaaaaattt 26340 actcttaata attctgacta tgtcaatttt aacaatgaca ctataatggc tgcattgatg 26400 aatgaatcgt ttcaattcag cccatcatat gttgatgttt catcaataag taattttatt 26460 attggtgaaa atgagtatca tgaaatacaa ggttctattc agcaagtatg taaggatatt 26520 aaccgagttt atttgatgga atcagaaggg attctatatc tttttgagcg ttatcaacct 26580 gtagttaaag tatctaatga taaaggacaa acctggaaag ctgtaaagct cttcaatgac 26640 cgcgtaggat atcctttatc taagacagta tattaccaat ctgcgaacac aacatacgtt 26700 ctaggatacg acaagatttt ctatggccgc aaatcgactg atgttagatg gtcagctgat 26760 gatgtcagat ttagttcgca ggatataaca ttcgctaaac tcggtgacca attacatcta 26820 ggatttgatg tagaaatttt tgccacttac gcgactttac cagctaatgt atatcgcatt 26880 gcagaagcta ttacttgcac cgatgattac atttacgttg tcgccagaga caaagttaga 26940 tacataaaaa cgagtaatgc acctatagat tctgatccat tatctccaac gtattcggaa 27000 aggctatttg aacctgatac gatgactata actggaaatc ctaaagcagt atgttataaa 27060 atggattcta ttggtgataa agtctttgct cttattattg gtgaagttga aacattaaat 27120 gctaatccta gaacatcaaa aataattgat tctgccgata aaggaatata tgttttaaat 27180 catgccacga aaacatggaa aagagttttt ggcaacactg aagaagaaag aagacgtatt 27240 caacccggat atgcgaatat gtcaactgac ggtaaattag tttctctgtc ttcgagtaat 27300 tttaaatttt taagtgataa tgttgttaat gaccctgaaa ctgcagcaaa atatcagtta 27360 attggtgctg tcaaatatga atttcctcgt gaatggttag ctgataagca ttatcatatg 27420 atggcattta tagcggatga aaaatctgat tgggagactt ttactcctca accaatgaaa 27480 tactacgcag aaccgttctt taactggtct aaaaaatcta acacacgttg ttggataaac 27540 aactctgata gagctgtagt agtttatgct gatttaaaat acaccaaagt tatagaaaat 27600 attccggaaa catcaccaga tagattagtt catgaatact gggatgatgg tgattgtacg 27660 atagtaatgc caaatgttaa attcacggga tttaaaaaat acgcgtctgg gatgcttttt 27720 tataaatctt ctggtgaaat aatttcttac tatgatttta actatcgtgt gagagataca 27780 gtagaaatta tttggaagcc aactgaagta tttttaaaag catttttaca aaaccaagag 27840 catgagactc cttggtcacc agaagaagag cgtggactag ctgaccccga tttaagacca 27900 ttaattggca caatgatgcc tgattcttat ttgctacagg attcgaattt tgaagcattt 27960 tgcgaagcat atattcagta tctttctgat ggatacggaa ctcaatacaa taatttacga 28020 aatttaattc gtaacaaata tccacgagaa gagcatgcat gggaatattt gtggtcagag 28080 atatataaaa gaaacattta tttaaatgct gataaacgcg atgctgttgc gagattcttt 28140 gaatcacgta gctacgattt ttattctact aaaggaattg aagcatcata caagtttctt 28200 tttaaagttc tttataatga agaagttgaa attgaaattg aatctggggc tggtactgaa 28260 tatgatataa tcgttcaatc tgattctttg actgaagatt tagtaggaca aacgatttat 28320 acggcaacag gaagatgtaa tgttacttat atagaaagaa gctattctaa tggtaaattg 28380 caatggaccg taactattca taatcttttg ggaagattga ttgccggtca agaagttaaa 28440 gcagaaagac ttcctagttt tgaaggcgaa attattcgtg gagttaaagg gaaggatttg 28500 cttcaaaata atatagacta tattaataga agtcggtcat attatgtaat gaaaattaaa 28560 tccaatttgc cttcttcccg ctggaaatct gacgttattc gttttgttca tccagtagga 28620 tttggattta tagcaattac ccttttaaca atgtttatta atgttggttt aactcttaaa 28680 cacacagaga ctataattaa taaatacaaa aactataaat gggattctgg attgcctact 28740 gaatatgctg atagagtagc taaattaact ccaaccggtg aaattgagca tgattcagta 28800 acaggcgaag caatttatga gcctggccca atggctggcg tagaatatcc tcttcctgat 28860 gactataatg ctgaaaataa taattcaata tttcaaggtc aattgccatc tgaacgacgt 28920 aaattaatga gtcctctatt tgacgcttct ggaacaacat ttgcacaatt tagagattta 28980 gttaataaac gtctaaaaga taatatagga aatccaagag accctgaaaa tccaacacag 29040 gttaaaatag atgaatgatt caagtgttat ctatcgtgcg atagttactt caaaatttag 29100 aacagaaaaa atgttgaatt tttataattc aattggaagt ggtccggata aaaacactat 29160 ctttatcaca tttggaagat cagaaccgtg gtcatcaaat gaaaatgagg tgggttttgc 29220 cccaccttat ccaaccgatt ctgtattagg cgtaactgac atgtggacgc atatgatggg 29280 aacagtaaaa gttcttccat caatgcttga tgctgttatt cctcgtcgag attggggaga 29340 tactagatat ccggatccgt atacatttag aattaacgat attgtagtgt gtaactcagc 29400 tccttacaac gctactgaat caggcgcagg ctggttagta tatcgttgtt tagatgttcc 29460 tgatactgga atgtgttcaa tcgcatcttt aactgataag gatgaatgcc ttaagctagg 29520 tggaaaatgg actccttctg ttaggtcaat gactcctcct gaaggtcgag gagatgctga 29580 aggaacaatt gaacctgggg acgggtatgt atgggaatat ctttttgaga ttccgcctga 29640 tgtatctata aatagatgca cgaatgaata tatcgtggtt ccttggcccg aggaattaaa 29700 agaagacccg actagatggg gatatgaaga taacctcact tggcagcaag atgattttgg 29760 attaatttac cgtgttaagg caaatactat ccgttttaaa gcatatttag attcagttta 29820 ttttcctgag gctgcattgc cgggaaataa aggatttaga caaatatcaa taatcacgaa 29880 tcctcttgaa gctaaagctc atccaaatga cccaaacgtt aaagctgaaa aggattatta 29940 tgatccggaa gatttaatga ggcattcggg cgaaatgatt tatatggaaa ataggccacc 30000 tattatcatg gcaatggatc aaacagaaga aatcaatatt ctgtttacat tttaacttaa 30060 gggagcccat gggctccctt tttctttata aatactataa actcataagg aaaccgctat 30120 gttcattcaa gaaccaaaga aattgattga taccggcgaa attggtaacg cttctactgg 30180 tgatatctta ttcgacggtg gtaataaaat taatagtgat tttaatgcaa tttataacgc 30240 gtttggcgat cagcgtaaaa tggcagtagc aaatggtact ggtgctgacg gccaaattat 30300 ccatgctact ggatattatc aaaagcattc tatcacagag tacgcaactc cggtgaaagt 30360 tggtactaga catgatattg atacctctac tgtaggtgtt aaagttatca ttgaaagagg 30420 cgaacttggc gactgcgttg aatttattaa ctcaaatgga tctatatcag ttactaatcc 30480 tttaacaatt caagccattg attcaattaa aggtgtttcg ggtaatttag tagtaactag 30540 cccatatagt aaagtaactt tacgctgtat ttcatctgat aattctacat cggtttggaa 30600 ttattctatt gaaagcatgt ttggacaaaa ggaatcacca gctgaaggta catggaatat 30660 ttctacatcc ggatcagttg atattccatt atttcatcgt actgaataca atatggctaa 30720 attgttagtt acatgccaat cagtagatgg aagaaaaatt aaaacggcag aaataaatat 30780 tcttgtagat actgttaatt cagaggtcat ttcttctgaa tatgctgtca tgcgagttgg 30840 gaatgaaacc gaagaagacg aaatcgctaa tattgcattt agtattaaag aaaattacgt 30900 aacggcgact ataagttctt caactgtcgg tatgagagca gcagttaaag ttatcgctac 30960 gcagaaaatc ggggtggctc aataatgaaa caaaatatta atatcggtaa tgttgttgat 31020 gatggtaccg gtgactacct gcgtaaaggt ggtataaaaa taaatgaaaa ctttgatgaa 31080 ctttattatg aacttggtga tggagatgtt ccatattcag ccggtgcctg gaaaacttat 31140 aatgcttcat ctggacaaac actaacggca gaatggggaa aatcatacgc tattaatacc 31200 tcttctggaa gagtaactct acaacttcct aaaggaactg ttaatgatta caacaaggta 31260 attagagcta gagacgtatt cgctacatgg aacatcaatc cagttacttt agtagccgct 31320 tctggtgata ctattaaagg atcatcgtca tcagttgaaa ttaatattca atttagtgat 31380 ttagagctcg tttattgcgc tccaggacgc tgggagtatg tcaaaaataa gcaaatcgat 31440 aaaattatca gttcagacat tagtaatgta gctcgtaaag aatttttagt cgaagttcaa 31500 gggcaaacag actttttaga tgttttccgt ggaactagtt ataatgtcaa taacatcaga 31560 gtaaaacatc gtggtaacga attgtattac ggtgatgtat ttagcgaaaa cagtgacttt 31620 ggctctccgg gcgaaaatga aggcgaatta gttcctcttg atggatttaa tattcgatta 31680 agacagcctt gtaatattgg tgacactgtt caaattgaaa catttatgga tggtgtatca 31740 caatggagaa gttcatatac tagacgccaa ataaaagtac tagattcaaa actaacatca 31800 aagacttctt tagaaggaag catttatgtt actgatttat cggcgatgaa atcaattcca 31860 ttttctgcat ttggattaat tcctggtgaa cctattaatc ctaactctct tgaggttcgt 31920 tttaatggaa ttttacagca gcaggctgga acagctggat atcctctgtt tttgtgtgaa 31980 ggcgctaatt cagatacgca agaaggatgt atatctcttg gtggcgaatg gaaagaatca 32040 aacaccgatt attctataga atatgaagac ggaaaaccta tcagtctttt atttgataga 32100 aaatttgaat ccggtgacat tatcgttata acatggttca ataatgattt aggaactctt 32160 ttagaaaaag atgacatcat tgaattgact gatgaccgtt atgttagtaa agggtcagct 32220 actgaagtta ctggtgatgt ggccttaaca gattttgata aaatcggttg gccaaatgtt 32280 gaaaaagttg attcttatac tagaacgtat aattcaatat catctatttt cgacagcatt 32340 tatcctgttg gttcaattta tgaaaatgct ataaacccaa ataatccggt gacttatatg 32400 ggatttggtt catggaaatt atttggtaaa ggacaagttt tagtaggatg gaatgatgat 32460 gttacagatc caaactttgc attaaacaat aatgatttag attctagcgg aaatccttca 32520 cataccgccg gtggaacagt tggaacaaca acagtgacac ttgaaaacgc aaatcttcct 32580 gcaactaaaa ccgacgaaag agttttaatt gaagacgaaa acggatcagt tattattgga 32640 ggttgccaat atgacccaga tgaaactggt cctatatata caaaatatcg tgaagattac 32700 gcaacaacaa actcttcaca tactcctcct gctaatatta gtaatattca accgtctatt 32760 actgtatacc gttggataag gattgcataa tgagtttact taataataaa gcgggagtta 32820 tttcccgctt agcagatttt cttggtttta gaactaagaa aaatgatatt tcggttatga 32880 ataatcagcc ggtaggcgct gtaacaattt cacaaatagc aaaaggtttt tatgactcaa 32940 atgtagaatc tgctatcaat gatgttagaa atatggcaga gcaacaggtt ggagctgtat 33000 tagttaatat aagcggcgta tctcctactg gcgtgcaaca aacagactat tggtcatttg 33060 aaggaaccgt tactgatact tcagccaaac caggtgatcc agttattgtt aacatgtttg 33120 gtattccagt taaagctact aatggaatga cttcaattga atttactagt gctgttagaa 33180 cagctctaca ggaaatggtt gtaaaattta ttgcaattga ttcgtttgaa gaccatccta 33240 ctatagggaa taaaatacaa gttaagtatt tagataacca agaacatatc ttagagcaat 33300 actctgataa aggaattact ttcaaacaag aaataatttc tccttctaaa cctggatacg 33360 gaacttggca attattaggt gcgcaaactg tcacgctaga tagtcacaca caacctacgg 33420 tattttatta ttttgagaga atagcatgag taacaataca tatcagcacg tatcaaatga 33480 atcaaaatat gttaaattcg atccagtagg atcgaatttt cctgacactg tcacgacagt 33540 gcagtctgca ttatcaaaaa taagtaatat cggtgtaaat ggtattcctg atgcaactat 33600 ggaagttaaa ggaatagcaa tgattgcgtc agagcaagag gttttagatg gaactaataa 33660 ttctaaaatc gttacaccag ctacattagc aacaagatta ttgtatccaa atgctactga 33720 aactaagtat ggtttaacgc gctattcaac aaatgaagaa acattagaag gctcagataa 33780 taattcatca ataacgccgc aaaaactgaa ataccatact gacgatgtgt tcaaaaatag 33840 atattcgtct gagtcatcaa acggggttat taaaatatca tctacacctg cagctttagc 33900 tggagttgat gatactacgg caatgactcc attaaaaacg caaaaacttg caataaaatt 33960 aatttcacaa atagctcctt ccgaagatac tgcatcagaa tctgtgagag gtgtagttca 34020 attatctact gttgcgcaaa ctcgtcaagg aactctccgc gaaggatatg caatttctcc 34080 gtataccttt atgaattctg ttgcaacaca agaatataag ggtgttatac gtttaggaac 34140 acaatcggaa attaacagta atttaggaga tgttgcagta acaggtgaaa cactaaatgg 34200 tcgaggagct actggttcta tgcgtggggt ggtaaaatta acgacgcaag ccggtattgc 34260 ccctgaaggt gatagctctg gagcattagc atggaacgca gatgtaatta atactcgtgg 34320 tggacaaact attaatggtt ctttaaattt agaccatctt acagcaaacg gaatttggtc 34380 gcgcggcgga atgtggaaaa atggcgatca acctgttgcc actgaaagat atgcgtcaga 34440 aagagttcca gttggaacta ttatgatgtt tgcgggagat tcggcacctc cgggttggat 34500 tatgtgccac ggtggaacag tgtcaggaga tcaatatcct gattatagaa acacagttgg 34560 aacaagattt ggtggggatt ggaataatcc agggattcct gatatgcgag gtcttttcgt 34620 cagaggagct ggcacaggag gtcatatttt aaatcaacga ggacaagatg gttatgggaa 34680 ggatagactt ggtgtaggat gtgacggaat gcatgttggt ggtgttcaag cacaacaaat 34740 gtcataccat aaacacgccg gtggttgggg ggaaaataac agaagtgtag gcccatttgg 34800 cgcgtctgtt tatcaaggat atcttggaac tagaaaatat tccgactggg ataatgcttc 34860 atacttcact aatgatggat ttgaattggg tggaccgaga gatgcacttg gtacacttaa 34920 tcgtgaagga ttaattggtt atgaaactag accatggaat atatcattaa actatattat 34980 taaaattcat tactaaggat tacaaatgat tgaattaaaa gagttacctt ttgttgatag 35040 cgttcctggc gaaggtcagg agcgtatttc atggattaaa aatggtgaag aaatattagg 35100 agctagtact aagtatggaa acgatggatc aatgaataga ccaactgttt ccgtgtttaa 35160 aaatgttgag gttcttgacg aaaatatagg aattcttaaa acagcattag aaacatccca 35220 ggaagatatt aaaaccattc agggtatctt agatgtatct ggtgatatag aagctttatc 35280 gcaaataagt atcaataaaa aggatatcac tgatcttaaa acgcttacga gtgaacatac 35340 cgaaatatta aatggaacta ataatactgt cgatagcatt cttgctgaca ttggtccatt 35400 taattcgcaa gcaaattcag tttatagaac gattagaaat gatttgttat ggattaaaag 35460 ggaattagga caatatgctg ggcaagacat taacggtctt cctgttgtag gaaatagcag 35520 cactggtatg aagcaccgta tcattaataa tacagatgct ataacttccc aaggaatacg 35580 cctaagtgat ttggaagaaa aatttattga atctgatgta ggttcgctta caatcgaagt 35640 aggaaatctt agacaggaat taggacaaag accgccttca tttagtgaaa gtatatattc 35700 acgtgttcat aatttagatc aatcgcagat taatcttagt tccgaaatta aatctatcaa 35760 aacttctatt ggatatccag gaaatacttc aataatcaca gatgttaaca ctaataccca 35820 agaaatttca gctttaaatg atgaactaaa taaaagcgga ggtgttaaac agcgattaac 35880 tgtcattgaa acatcaattg gctcagatga tattccttct agtattaaag gtcaaattaa 35940 agataatact acctctattg agtctttaaa tggaattgta ggtgaaaaca cctcgtctgg 36000 tttaagagct aatgtttcgt ggttaaacca aattgttgga actgattcta gtggaggtca 36060 gccttctcct cctgggtctc ttttaaatag ggtttcaact gttgaaactt cagttaatag 36120 actgaacaat gatgttcaaa acttacaagt tgaaattggt aataacaatt ccggaattaa 36180 aggccaagtt gttgcactaa ataaactagt aagcggcaca aatccaaatg gttcaacagt 36240 agaagagcgc ggattaacta attcaataaa ggctaatgaa actaacattt cttctattaa 36300 tcaagaaatg cgtagtatta aaagtaatgt atcttcatta cagggggatg ttcagacttt 36360 acaggaagca ggttatatcc ctgaagctcc aaaggatggt caagcttacg ttcgtaaaga 36420 cggcgaatgg gtactacttt ctaccttttt atcaccagca taacatgggg ccgcaaggcc 36480 ccaaaggatt tttaaatgtc aggatataat tctcagaatc caaaggagct caaagatgtc 36540 attctaagac gtttaggggc tccaattatt aatgttgagt taacacccga tcaaatctac 36600 gattgcatcc agcgtgccct agaattatac ggtgaatacc attttgatgg acttaacaaa 36660 ggttttcatg tattttatgt aggagatgac gaagaaaaat ataagaccgg agtcttcgat 36720 ttaagaggtt ccaacgtatt tgcagtaact cgtattttac gcacaaatgt tggatcaata 36780 acatctatgg acggtaacgc tacttatccg tggtttactg actttctttt aggaatggct 36840 ggtattaatg gtggtatggg aacgtcttgt aatagatttt atggaccaaa tgcctttgga 36900 gctgatttag gatattttac ccagcttacc agttacatgg gaatgatgca agatatgctt 36960 tcgcctattc cagacttttg gtttaattca gcaaatgaac aactcaaagt catgggaaac 37020 ttccaaaaat atgatttaat tatcgtagaa agctggacta aatcatatat tgatacaaac 37080 aaaatggttg gaaatacagt aggatatgga acagtcggtc cgcaagatag ttggtcatta 37140 tctgaacgat ataataatcc agaccataat ttagtaggtc gagttgtggg gcaagatcca 37200 gatgttaaac aaggcgctta taataaccgt tgggtgaaag actatgcaac agctttagct 37260 aaagaattaa atggccaaat tttagcacgc caccagggta tgatgcttcc tggcggtgtt 37320 acgattgatg gacaacgctt aatagaagaa gctcgattag aaaaagaagc actgcgcgaa 37380 gaattatact tacttgaccc tccatttgga atttttgtag gttaatatgg ctacttatga 37440 taaaaatctt tttgctaaat tggaaaacca cacaggttat tctcagacca atgaaactga 37500 aatattaaat ccttatgtaa atttcaatca ttataaaaac agccaaatat tagctgatgt 37560 attagtggct gaaagcattc aaatgcgagg tgtagaatgc tattatgttc caagagagta 37620 tgtttcccct gatttgatat tcggtgaaga cttgaaaaat aaatttacta aagcttggaa 37680 atttgccgcg tatctgaatt catttgaagg atatgaagga gctaaatcgt tctttggtaa 37740 ctttggtatg caagtacaag acgaagtgac tttatctatt aacccaaatt tatttaagca 37800 tcaagttaac ggaaaagaac cgaaagaagg cgatttgata tattttccta tggataacag 37860 cttattcgaa attaactggg ttgaaccata tgatccattt tatcaattag gccaaaacgc 37920 tattcgtaaa attacagcag gtaaattcat ttattctgga gaagaaatta atccggttct 37980 acagaaaaat gaaggaatta acattccgga attcagtgaa ttagaattaa atcctgttcg 38040 caatcttaat ggcattcatg atattaatat tgatcagtat gctgaagtag atcaaattaa 38100 ttctgaagct aaagaatatg ttgaacctta tgttgttgtc aataacagag gcaaatcttt 38160 tgaatctagc ccatttgata atgatttcat ggattaataa atattataaa ctaattaaag 38220 cccagattag gagaaatcat gtttggttat ttttataatt cgtcttttag acgatatgct 38280 accttgatgg gcgatttgtt ttcaaatatc caaatcaaac gtcagttaga atctggtgat 38340 aagtttatac gtgttcctat tacgtatgca tcaaaggaac acttcatgat gaaattaaat 38400 aaatggacat caataaattc acaagaagat gtagctaaag ttgaaactat tctacctcgt 38460 ataaatttac atttagttga ttttagctat aatgctccat ttaaaacaaa cattttaaat 38520 cagaatttac tgcaaaaagg tgcaacttct gtagtatcgc agtataatcc atctcctatt 38580 aaaatgattt atgaattgag tatatttact cgctatgagg atgatatgtt tcaaatagtt 38640 gaacagattc ttccatattt tcagcctcat tttaatacaa ctatgtacga acagtttgga 38700 aatgatattc catttaaaag ggatattaaa attgtattaa tgtctgctgc tatagacgaa 38760 gctatagatg gagataattt atctcgtcgt agaattgaat ggtcactaac atttgaagta 38820 aacggatgga tgtatcctcc agtagatgat gcagaaggat taattcgtac tacttataca 38880 gattttcacg ccaatacaag agatttgcct gatggcgaag gtgtttttga atctgtcgat 38940 aacgaagttg ttcctcgaga tattaaccca gaagactggg atggaacagt aaaacaaact 39000 ttcactagta atgtaaatag accaacaccg ccagaacctc ctggcccaag aacatagagg 39060 ttattatgga aggtcttgat ataaacaaac ttttagatat ttctgacctc cccggaattg 39120 acggggagga aattaaagta tatgaacctc tgcaattagt agaagttaaa agcaatcctc 39180 aaaaccgtac tccagactta gaagatgatt atggagtagt tcgtcgaaat atgcattttc 39240 aacaacaaat gctaatggac gcggccaaga tttttcttga gacggcaaag aatgctgatt 39300 ctcctcgtca catggaagta tttgcaactc ttatggggca aatgactacg acgaacagag 39360 aaatactgaa gcttcataaa gatatgaaag atattacatc tgagcaggtt ggcaccaaag 39420 gcgctgttcc tacaggtcaa atgaatattc agaatgcgac agtattcatg ggttcaccaa 39480 cagaattaat ggacgaaatt ggtgatgctt acgaggctca agaagctcgt gagaaggtga 39540 taaatggaac aaccgattaa tgcattaaat gatttccatc cgttaaatga agctggaaaa 39600 attttaataa aacacccaag cttagcggaa agaaaagatg aagatggaat tcactggata 39660 aaatctcagt gggatggaaa atggtatcct gaaaaattca gtgattacct tcgtctacac 39720 aaaatagtaa aaattccaaa caactctgat aagcctgaat tatttcaaac ttataaagat 39780 aagaataata aaagatctcg gtatatgggt cttcctaact tgaaacgagc taatattaaa 39840 acacaatgga ctcgtgaaat ggttgaggaa tggaaaaaat gccgagacga tattgtttat 39900 tttgcagaaa catactgtgc cattactcat attgactatg gtgtcataaa agttcaatta 39960 cgtgattatc agcgtgatat gctcaaaata atgtcatcta aacgtatgac tgtttgtaat 40020 ctatcgcgcc agctcggtaa aacaactgta gtagctattt tccttgcaca ctttgtatgt 40080 tttaacaagg ataaagctgt aggtattctt gcgcacaaag gctcaatgtc tgcggaagtt 40140 ttagaccgta ctaagcaagc aattgaactg cttcctgact ttttacagcc aggaattgtt 40200 gaatggaata aagggtctat tgaacttgat aatggttcct caatcggagc ctacgcttcc 40260 tctcctgacg cagttcgtgg taactcattc gcaatgattt acatcgatga gtgtgtagcc 40320 aaagatacta aagtaactat tagatgtaaa gctacaggcg aaataaaaga aatgactatg 40380 ctggaagtta aagcattggc aattacacaa aaagaggcaa aggatgcgca aaaataaaaa 40440 tggaaggcct atccagcgat taattatcgc ttcaagatat atttgccctg aatgcggtga 40500 atttaatgca aaatgtgcag gatatagatg caaaccttgc ggaagaaagg cccaaggtag 40560 agcaatgtct aatctgtata agaccaatca tgctgaaatg gtgaccaaat gcaataaacc 40620 ttatacagaa gatactagaa taaaacattc gaatacagtt aagaaaaaaa ttcttaacgg 40680 agaatttact ccaaagtcta ataatcgtag aacatggaaa cggatttaca aagatggcca 40740 tgcctttaga agttcatggg aattaaaatt ctatgattac tgtttaaata acaatatcaa 40800 agtagaatat gaagccctta gaattccata cgaatttgaa ggttccacac atatctatat 40860 tacggatttt attagtcata ccgagaaaaa agtatatgaa ataaaaccta attccatgat 40920 agatgaaaag gccctagcca aagaaaagta tgcaactaaa tggtgcaaag aaaacggtta 40980 tgaatatgtc tttattacgg aggacttctt atgcaatttt tagaattaga cggttatgaa 41040 gtcctcaccg acgacgggtt taaagacttc aatggtatta aatgcacttt cggacttata 41100 tggcgtactt gttttgatga tggaagccat ttagattcat cggacggaca tttaatcaaa 41160 atgaaaaatg gcaagtttaa aaaggccaaa aatattaaag ttggcgatat aacttctact 41220 ggtcttaaag taacttcatg tgatgaattt ttagaacaag atgagctgtt tgatttgaca 41280 aatgtagccg acggatatca ttataaaact aataatgtcg aatcacacaa ctgtgcattt 41340 attccaaatt tccatgattc ctggcttgct attcagccag taatttcatc tggtcgtcgt 41400 tcgaaaatta ttattactac gactcctaat ggattaaatc atttttatga tatttggact 41460 gcagccgttg aaggtaaatc tggatttgaa ccatacactg ctatttggaa ttcagttaaa 41520 gaacgtcttt ataacgatga agatattttt gacgatggat ggcaatggag tatacaaacc 41580 attaatggtt ccactttagc acaattccgt caagaacata ctgcagcgtt tgaagggact 41640 tctggtacat taatttcagg aatgaaatta gctgttatgg atttcattga agtaactcca 41700 gatgatcatg gttttcatcg atttaaaagc cctgaaccag atagaaaata tatcgcaact 41760 ctagactgct cagaaggtcg tgggcaagat taccacgctt tacatattat tgatgttacc 41820 gatgatgtgt gggaacaagt tggtgtttta cactcaaaca ctatttctca tttaattcta 41880 cctgacatcg ttatgcgtta tttagtagaa tataatgaat gcccagttta tattgaatta 41940 aatagtactg gtgtgtcagt tgctaaatcg ctttatatgg atttagaata cgaaggcgtt 42000 atttgcgatt catatactga tttaggaatg aagcaaacta aacgcacgaa agcagtagga 42060 tgctctacat taaaagacct tattgaaaaa gataagctta ttattcatca ccgtgcaact 42120 attcaagagt ttagaacgtt tagtgaaaaa ggtgtgtctt gggcggctga agaaggttat 42180 catgacgatt tagtaatgtc tttagtgatt tttggatggt tatcaacaca gtcaaaattt 42240 attgattatg cggataaaga tgacatgcga ttagcatctg aagtgttttc aaaagaactt 42300 caagatatgg gtgatgaata cgcgccagtt atatttgtgg attcggttca ttctgctgag 42360 tatgttccag tatctcatgg tatgtcaatg gtataaatat attaaagcat attaaagagg 42420 attaaaaatg actttattat ctccgggcat tgagctcaaa gaaactacgg ttcaaagcac 42480 cgttgttaat aactctactg gtacagcagc tttggccggt aaattccagt ggggtcctgc 42540 ttttcagatt aaacaggtta caaatgaagt agatttagtt aatacttttg gtcaaccaac 42600 cgctgaaact gctgactatt ttatgtctgc gatgaatttc ttgcagtacg gaaatgactt 42660 acgagtagtt cgtgctgttg atagagatac cgctaaaaac tcatctccga ttgctggtaa 42720 tattgaatac acaatttcta ccccaggtag taactatgca gttggagata aaatcacggt 42780 caaatatgtt tcagatgata ttgaaactga aggtaaaatt accgaagtag acgcagatgg 42840 aaaaattaag aaaattaata ttcctactgc aaaaattatt gctaaagcta aagaagttgg 42900 cgaataccca acattaggtt ctaactggac tgcagaaatt tcttcatctt cctctggttt 42960 agctgcagta ataactcttg gaaaaattat tactgattct ggtattttat tagctgaaat 43020 tgaaaatgct gaagctgcta tgacagaggc tggctttcaa gcaaatctcg aaaaatacgg 43080 aattccagga gtagtagctc tttatccagg cgaattaggc gataaaattg aaattgaaat 43140 cgtatctaaa gctgactatg caaaaggagc ttctgcatta ctcccaattt atccgggcgg 43200 tggtactcgt gcatctactg ctaaagctgt gtttggatat ggaccacaaa ctgattcaca 43260 gtacgctatt atagttcgtc gcaatgatgc tattgttcaa agtgttgttc tttcaactaa 43320 gcgtggtgaa aaagatattt acgatagtaa catctatatc gatgactttt tcgcaaaagg 43380 tggttcagaa tatatttttg caactgcaca aaactggcca gaaggcttct ctggaatttt 43440 aactctgtct ggtggattat catcaaatgc tgaagtatca gcaggagatt tgatggaagc 43500 ttgggacttc tttgctgacc gtgaatccgt tgatgttcag ctgtttattg cgggttcttg 43560 tgccggtgaa tctttagaaa cagcatctac tgtccaaaaa cacgtcgttt caattgggga 43620 tgctcgccaa gattgcttag tattgtgctc tcctccacgt gaaactgtag ttggaattcc 43680 tgtaactcgt gcagtagata atttagttaa ctggagaact gcagcaggtt catacactga 43740 taataacttt aatatcagtt caacctatgc agcaattgat ggtaactaca aatatcagta 43800 tgacaaatat aatgatgtga atcgttgggt tccattagca gctgatattg ctggtttatg 43860 cgcaagaact gataacgtat ctcagacttg gatgtctcca gctggttata atcgtggtca 43920 gattcttaac gttattaaac ttgctattga aactcgccag gctcagcgcg accgtttata 43980 ccaagaagct atcaacccag taactggtac aggtggcgat ggttatgtat tgtatggtga 44040 taaaacagct acttctgttc cttctccatt tgatcgtatt aacgttcgtc gtctgtttaa 44100 tatgttgaaa acgaatatcg gacgtagttc aaaatatcgt ttgttcgaat taaacaacgc 44160 gtttactcgt tcatcattcc gcacagaaac tgcccagtac ttgcagggaa ttaaagctct 44220 cggtggaatt tatgaatatc gtgtagtttg cgatacaaca aataacactc cgtcagtaat 44280 tgatagaaat gagtttgttg caacattcta catccaaccg gcgcgcagta taaattatat 44340 ccaacttaat ttcgtcgcaa cggctactgg tgcagatttc gatgagttaa ctggtcttgc 44400 tggttaatac ggtgcattct aaaggcctgt ttcggcaggc catataaata cactatatcc 44460 ttaattcttt aattctatat gccctaggtt aaacataggg atataaatac tacagaggct 44520 aatatgtttg tagatgatgt aacacgagcg tttgaatctg gtgattttgc tcgacctaac 44580 ttattccaag tagaaatttc ttatcttgga caaaatttta cgtttcaatg taaagccact 44640 gctttaccag ctggtattgt agaaaaaatt ccagtcggat ttatgaaccg taaaattaac 44700 gtagcaggcg atcgtacatt cgatgactgg actgttacag taatgaacga tgaagctcat 44760 gatgctcgcc agaagttcgt tgattggcaa agcattgctg cggggcaagg aaacgaaatt 44820 actggtggaa aacctgcaga gtataaaaag agcgctatcg ttcgtcaata tgctcgtgac 44880 gctaaaacag taacaaaaga aattgaaatt aaaggtctgt ggcctactaa cgtgggtgaa 44940 cttcaattag attgggattc aaacaatgaa atccaaacat ttgaagtaac tcttgctctc 45000 gattattggg aataaaatga atggggagaa atccccatcc tgcttaaagc agagaagtcc 45060 attataaata taactataat tcccatttgg agaatacaat gaaatttaat gtattaagtt 45120 tgtttgctcc atgggctaaa atggacgaac gaaattttaa agaccaagaa aaagaagatc 45180 ttgtttccat tacagcccca aagcttgatg atggagcaag agaatttgaa gtaagcgcaa 45240 atgaagctgc ttctccttat aatgctgcat tccaaacaat ttttggttca tatgaaccag 45300 gaatgaaaac tactcgtgag cttattgata catatcgtaa tctcatgaat aactatgaag 45360 tagataatgc agtttcagaa atcgtttcag acgctatcgt ctacgaagat gatactgaag 45420 tcgtagcgtt aaatttggat aaatctaaat ttagcccaaa aattaaaaat atgatgttag 45480 atgaatttag tgatatatta aatcatctat cgtttcaacg aaaaggttct gatcatttta 45540 gacgttggta tgttgattca agaattttct ttcataaaat cattgatcca aaacgtccaa 45600 aagaaggcat aaaagaatta cgtagattag atcctcgcca agttcagtat gttcgtgaaa 45660 ttataacaga aactgaagct ggcacaaaaa tagttaaagg ttacaaagaa tattttatat 45720 atgatactgc ccatgagtca tatgcatgtg atggtagaat gtatgaagct ggcacaaaaa 45780 taaaaattcc taaagctgcc gtagtttatg cccattctgg attagtcgat tgttgcggta 45840 aaaatatcat cgggtattta catcgtgctg ttaaacctgc taaccaatta aaattattag 45900 aagatgctgt agtcatttat cgcattactc gtgctcctga ccgccgtgtt tggtatgtag 45960 acacaggtaa tatgcctgct cgtaaagctg ctgagcacat gcaacatgtc atgaacacga 46020 tgaaaaaccg tgtagtatat gatgcatcaa ccggtaaaat aaaaaatcaa cagcataata 46080 tgtctatgac cgaagactat tggttgcagc gccgtgacgg taaagctgtg acagaagttg 46140 atactcttcc tggtgctgat aatactggca atatggaaga tattcgttgg tttagacaag 46200 ctctttatat ggcattacgt gttcctcttt cacgcattcc gcaagaccaa caaggcggtg 46260 tgatgtttga ttctggaact agcattacac gtgatgaatt aacgtttgct aaatttattc 46320 gtgagttgca gcacaagttt gaagaagttt tcctagatcc gcttaaaaca aatcttttgc 46380 ttaaaggtat aatcacagaa gatgagtgga atgatgaaat aaataatatt aagatagaat 46440 ttcatcggga tagctacttt gctgagctca aagaagcaga aattttggaa cgaagaatta 46500 atatgctaac catggcagaa ccatttattg gtaaatatat ttctcacaga actgctatga 46560 aagatatttt gcagatgact gatgaagaaa tagaacaaga agccaagcaa attgaagaag 46620 agtctaaaga ggctcgtttc caagaccccg accaagaaca agaggatttt taatggaagg 46680 tttaattgaa gctattaaat caaacgacct cgtagccgct cgtaaattat ttgctgaagc 46740 catggctgca agaacgattg atttaattaa agaagaaaaa atcgctatcg ctcgtaattt 46800 cttaatcgaa ggtgaagaac ctgaagacga ggatgatgac gaagacgaag atagtgatga 46860 taaagacgac aaaaaagaca aagactctga cgaagacgag gatgatgaat aatgcttctg 46920 atccctgaaa ctcatgaatt agttctcgag aatgtcgaag cacttattcc tgaagcacag 46980 ggtcgctttg acgaattgtc ttctgcttta aataaagacg atataaatac agttgtcgag 47040 aatatgcttg atgatgaaac tgatttagcg gttgcattag cttctattaa tgaaaatatg 47100 ccgttaaatg aatttatcgt taaacatgtt tccgcccgtg gtgaaattac tcgcactaaa 47160 gatcgcaaaa cccgcgaacg aaatgcattt caaaccactg ggctgtctaa agcaaaacgt 47220 agacaaattg ctcgtaaagc taccaaaacg aagattgcca atccagcagg tcaatctcgt 47280 gctcagcgta agcgtaaaaa agctcttaaa cgccgtaaag cattaggatt aagctaatga 47340 atgaacccca attactaatt gaaacttggg gtcaacctgg cgaaattatt gatggcgtac 47400 caatgcttga atctcatgat ggaaaagact taggtttaaa acctggttta tacatcgaag 47460 gaatattcat gcaagcggaa gtcgtcaata gaaataaacg tctttatcca aaacgtatat 47520 tagaaaaagc ggtaaaagac tatattaatg agcaagtttt aactaaacaa gctctcggag 47580 aattaaatca tcctccacgc gctaatgttg acccgatgca agccgctatc attatagaag 47640 atatgtggtg gaaaggaaat gacgtatacg gacgagctcg tgttattgaa ggtgaccatg 47700 gtcctggaga taaattagca gctaatattc gtgccggatg gattccagga gtttcttctc 47760 gtggattagg ttcattgact gacacaaata aaggttatcg tatcgtaaac gaaggattca 47820 aattaactgt aggtgttgat gcggtatggg gtccaagtgc tccagatgca tgggtaactc 47880 ctaaggaaat taccgaatca cagacggcgg aagccgatac aagtgccgat gacgcctata 47940 tggctctcgc agaggccatg aaaaaagcgt tataaatatt attatctaaa caacaggact 48000 acaaaatgct taaagaacaa ctgattgctg aagcgcaaaa aattgatgct tccgttgctc 48060 ttgatagtat tttcgaatca gttaatattt ctccggaagc aaaagaaact ttcggcactg 48120 tattcgaagc taccgtcaag cagcacgccg ttaaattagc tgaatctcat atcgctaaaa 48180 ttgctgaaaa agcagaagaa gaagtagaaa aaaataaaga agaagccgaa gaaaaagctg 48240 agaagaaaat cgctgagcaa gcttctaaat tcattgacca tcttgcaaaa gaatggctcg 48300 ctgaaaataa attagcagtt gataaaggca tcaaagccga actgtttgaa tccatgcttg 48360 gtggattaaa agagctcttt gttgaacaca acgttgttgt tccagaagaa tcagttgata 48420 ttgtagctga aatggaagaa gagctgcaag aacataaaga agaatcagct cgtctgttcg 48480 aagaactcag catgcgcgac gcatatatca attatgtgca gcgtgaagtg gcattgagcg 48540 aaagtactaa agatctgact gagtctcaaa aagaaaaagt ctctgctctg gtcgaaggta 48600 tggattattc agatgcattc tcaagtaaat tgagtgcaat cgtagaaatg gtgaagaaat 48660 ctaataaaga tgaaagcact attactgaga gtataaatac tcctgatact gaagcagccg 48720 gactgaattt cgtcactgaa gctgtagaag ataaagctgc acagggtgca gaagatattg 48780 taagtgtata tgcgaaagtc gcatctcgtt tctaatttta aaggttaaca caaatgacta 48840 tcaaaactaa agctgaactt ttgaacaaat ggaagccatt actggaaggt gaaggtttac 48900 cggaaattgc taatagcaaa caagcgatta tcgctaaaat ctttgaaaac caggaaaaag 48960 atttccagac agctccggaa tataaagacg aaaaaattgc tcaggcattc ggttctttct 49020 taacagaagc tgaaatcggt ggtgaccacg gttacaatgc taccaacatc gctgcaggtc 49080 agacttctgg cgcagtaact cagattggcc cagctgttat gggtatggta cgtcgtgcta 49140 ttcctaacct gattgctttc gatatttgcg gtgttcagcc gatgaacagc ccgactggcc 49200 aggtattcgc aatgcgcgca gtatacggta aagacccaat cgcttccggt gctaaagaag 49260 cattccaccc aatgtatggt ccagatgcaa tgttctctgg tcagggtgct gctaagaaat 49320 tcccagctct ggctgttaat actactacag ttgtaggtga tatctatact cacttcttcc 49380 aggacactgg tactgtgtat ctgcaagctt ccgctgtagt aacaattagt tcaagcgcaa 49440 ctgatgcaga taaattagat gctgaaatta agaaacaaat ggaagctggt gcactggtag 49500 aaatcgctga aggtatggct acttctatcg ctgaacttca ggaaggtttc aacggttcta 49560 ccgataaccc atggaatgaa atgggcttcc gtatcgataa acaagttatc gaagctaaat 49620 ctcgccagct gaaagctgct tactctatcg aattagcaca agacctccgc gctgttcacg 49680 gtatggatgc tgatgctgaa ctgtctggta ttctggctac agaaatcatg ctggaaatca 49740 accgtgaagt tgttgattgg attaactact cagctcaggt tggtaaatct ggtatgaccc 49800 tgactccggg ttctaaagct ggtgtatttg acttccagga cccaatcgat attcgtggtg 49860 ctcgctgggc aggtgaatcc tttaaagctc tgttgttcca gattgacaaa gaagcagttg 49920 aaattgctcg tcagaccggt cgtggtgaag gtaacttcat tatcgcttcc cgtaacgtag 49980 ttaacgttct ggcttcagtt gatactggca tttcttatgc tgcacagggt ctggctaccg 50040 gctttaacac tgatactacc aagtcagtat ttgctggtgt tctgggtggt aaataccgtg 50100 tatatatcga ccagtatgct aaacaggatt atttcactgt aggttataaa ggtccgaacg 50160 aaatggatgc tggtatttac tatgctccat atgtagctct gactccgctg cgtggttccg 50220 atccgaagaa cttccaaccg gtaatgggat tcaaaactcg ttacggtatc ggtatcaacc 50280 catttgcaga atccgctgct caggctccgg cttctcgcat ccagagcggt atgccttcta 50340 ttctgaatag ccttggtaaa aacgcttact tccgccgtgt atatgttaaa ggtatctaat 50400 ctttgacgat ttaagggacc ttcgggtccc tttagttgtt tttatggtat aaataaatca 50460 tataaactga aaggaaagcg caatggctaa aatcaacgaa cttctgcgcg aatcaaccac 50520 aacgaatagc aactcaatcg gtcgcccaaa tctcgttgct ttgactcgcg ctaccactaa 50580 attaatatat tctgacattg tagcaacgca aagaactaat caacctgttg ctgcttttta 50640 tggtatcaaa taccttaacc cagataacga atttacgttt aaaactggtg ctacttacgc 50700 tggcgaagct gggtatgtag accgagaaca aatcacagaa ttaacagaag agtctaaatt 50760 aactctcaat aaaggcgatt tattcaaata taataatatc gtttataaag tgttagaaga 50820 tacaccattt gcagatattc aagaaagcga cttagagtta gctcttcaga ttgcaatcgt 50880 tcttttaaag gttcgtctat tttctgacgc agcgtcaaca agcaaatttg aaagctctga 50940 tagtgaaatt gcggatgcta gattccagat taataaatgg caaaccgcgg ttaaatctcg 51000 taaacttaaa actggcatca cagttgaatt agcgcaagat ttagaagcaa atggattcga 51060 tgctcctaat ttcttggaag atttgcttgc aactgaaatg gcagatgaaa tcaataaaga 51120 tattctgcag tctttgatta cagtatcaaa acgttataaa gttacaggaa ttactgatac 51180 tggattcatt gatttgagtt atgcatctgc acctgaagct ggtcgttcat tataccgaat 51240 ggtatgtgaa atggtttcgc atatccaaaa agaatcaact tatacagcaa cgttctgtgt 51300 tgcttcagct cgtgctgctg cgattcttgc tgcatcaggt tggttaaaac ataaaccaga 51360 agatgataaa tatctttcac aaaatgccta cgggttctta gctaatggtt taccgcttta 51420 ttgcgatact aacagcccat tagattatgt aatcgttggt gtagtagaaa atattggcga 51480 aaaagaaatt gttgggtcaa ttttctatgc tccgtataca gaaggtcttg acttagatga 51540 ccctgaacat gtaggtgcat ttaaagttgt agttgaccca gaaagtttgc aaccatctat 51600 cggtttattg gttagatatg ctttatctgc aaatccttac actgtagcaa aagatgaaaa 51660 agaagcaaga ataattgatg gtggagacat ggataaaatg gcgggtcgtt cagatttgtc 51720 tgttttatta ggtgttaagc taccaaaaat tatcgttgat gaataaaaca aagggacctt 51780 tcggtccctt tttatttagc tcaccaactc aatccaagcc ggacgaagta catcttgtac 51840 cattttaact aattcctttt taatcaaaga aggattatcc gcttgagtta gagtaatacc 51900 ttcacgagaa gtttcttcca aaatatcttg aacagttagt cccatcacct ttccaaaatc 51960 ttttggacca atttcgccaa ttttagaaat aacgttattt actcggttca gtgtaacgta 52020 acaagctaaa atccccacca atttgttatc agcttctgac agttcaactt taactttaat 52080 aggcttatca gactttttct tttcactaaa tttggaattc ttgcatttga tggctacacg 52140 atttccatta tgaagccaag aaggataaca aggtttcaat acataacctt cagcggtaaa 52200 tacttcgcct ttggcttcgg cattccagac gcatttattt gcatcaacta atccagcatg 52260 gtctactgta aaattataat cttgaacgac agagtctaaa tcatttggca atttaataag 52320 ttcttcaaat ttaccacgac ccaaaagtgg agccatttta aatttgaatg tattacagaa 52380 tgattccatc atataatcat cgacataagt cacatcacca ctttcggtag taacaataat 52440 gtcaaataca taaaaatctt tatcgccata atcgacattc ttctgaatgc caggtccagc 52500 aaattcacca aagacttgat aagatacaac tgctgaagtt tccataatat cttgtactgc 52560 tttaatggaa tcagcgtaat tctttagaat aatttcatac ccaaagaaat cttcagcagg 52620 aagaatcggt ccagtacgtt tagcacaagt tgctttatcg cgctcaataa tcaacgagaa 52680 atttgtacca tgaatctttt cacgagctac ccattcgcca ccagtcaatc ctaaactgta 52740 aagtttttca ataaatttag aattgtaatg attttcaaga ctgctatact ttttaaacat 52800 aattaatcct caaaatgtaa tttctaacca atcaccatca cgctgatcac tattgacttt 52860 aaaactgaat ccttcttttc tcagccaatc accaatttct tcagtaatca atttatcacg 52920 agcaatacaa taataactaa aatgtgtttt accttgctca gctgctttat tagcaagttc 52980 cgaaaaatct ttaataaaac actctagttt aaactgttta cttttaagtg ctttttcgcg 53040 taattgatta gcaaaagatt cattttcata aagatcatac tgttccattt ttcacctttt 53100 tattaatatg tctttttcta tagacaactt tttctcgagt ctcaaattta ttcttagcag 53160 tcatagctcg agcccataat acagccacgt cttttgcctg taagtttaat tcacgagcaa 53220 tttcaatgaa tgactttcca gactcatgaa gagtaaacac cacaacctca gttctcataa 53280 tcaatctcat gttatcgagt tggtgccatt atatacatca ttttctgatt gtgttttgtg 53340 tgctttcaaa atgaagaaag gggccgaagc cccttatgat tatggatagg tatagatgat 53400 accagtttct aaagcagttt tatgaatgat gtatccatta cgcgattctt ggacatcaac 53460 ttctggatag tctttcatca tcttctgaag agtgtaacga tgcaagtagt acttactatc 53520 tggatcgtca gttttccaat ctttaccttc ttcggtcatt ttttggattt catccataac 53580 ccaccaaccg caccagatgt aagctgaagt acgatgtgga agaggatgaa cataaggtaa 53640 ttcaccttta ggagcaggag ctactttagc cgtgactgtt acattaccag ttttggtaac 53700 ggttacaggg ttataatctg cagcagatac aacaacagaa acgccaatca cttgggaccc 53760 tatatcagac gtgtcaatcg ctaaagtgct agtagaacct tctacaggag aaccatcttt 53820 ggtccaagaa taaaccccag ttgcacctcc cggagcaccg ataacgttgg ctttaaaaga 53880 tgcctcagaa ccttgttcag tcataataga ctcaggagtc agagtaactg aaactccgct 53940 catagtcttt ttggtaatag ttacattacc ggttttagta actgtaaccg acttataatc 54000 tggggcagaa acaacagccg aaacctcaat tacctgtgac ccgatagtag atgtatcaac 54060 ttctagagta tttgttgagc catcaacagg agacccgtct ttggtccatg aataagctac 54120 agatgctcct gccggcgctc cagtaacatc ggctttaaaa gatgcttctg ctcctttttc 54180 agcggtaatt gaactaggcg tcagagtaac agaaacggct cccatagtct ttttagtaaa 54240 aacaacctca ataccgttag tcgcagtagc tgggttataa tttgatgcag aaactgtaac 54300 ttcacaattc aatgtgtaat tagcttctgc gggttcagtt atggtaattg ttttagcagt 54360 ctgaccttca ataacgacag taccacgttt ccaaacataa gcaatgcttg caccttctgg 54420 agcaccaaca acgttagctg taactacctg agactgccca atctctttgg aaacagaagt 54480 cgggctcaag gttaaagtaa tcgcaggcat agttttgttc tgaacggtca gagtggtttc 54540 tgcctcagca gtttctgccg caccctctgc tggggtaaca gtagcaacta ctttaacagt 54600 cttactacct gcaggtcctg cagcaacata attcatagct gcggtgacag aagattgttt 54660 tacgccgttt actgtccaca caaacgtttc tgtgccttca gctgcggcac cagaagttgt 54720 tgcagtaaaa ttggttgttg ctccaatgac tgccgaagca gccaaaggag caatagatac 54780 gctataagcc ataggtgttc cttattttaa tgttacgaaa gaagagttgc gtgtttcacg 54840 aattaaaact gatccgtcac ggttaatgta ataaattaag ctaaataaag tttggtgtgc 54900 cgacgcgtgt tcaaaactag ttgggtgaga tttccaatcc ggagtttcag caatccattg 54960 ataaatccac caaggaacag tgcagaatcc tggatttttt ccaatcaact gaagattcgg 55020 actaaagttt tccggaagag taaatacaga cggcttttca gattcaataa tctcagctac 55080 agcttgttcg aatttttctt caacaaaagg agtatcttca attaaaacat cggtattttc 55140 aggaatttta tccgtttcta ctacttcaat tttaatgtca gatttaaccg gagaatcaat 55200 cagaagtgct gcttctggat tgacttcttc atcgtcatat tttaacccct ctgcagcatc 55260 agcagcattg attaagtctt taatagataa cccatcagtc tctggcatag gttcactagc 55320 gagcttctgg agggcttctt caatatcatt aacgatatta tcaaaagatt tattcttttt 55380 gacctttata ccaaactgtt cagcatattc agctaattta gccttagctt ctttattatc 55440 atcaagagcc ttcagctctg caatataatc tttatctatc ataatatttc ctcagtataa 55500 atatagatat atttattaca tggtatttag acatgactga cattaaagta catttttatg 55560 attttagtca cgtgagaatt gattgtgaag aaagtacatt tcatgaactc cgtgatttct 55620 ttagctttga agctgatggg tatcgtttta atccgaagta cagatatggc cactgggatg 55680 gacgaatccg tcttttagat tataatcgtc ttcttccatt cggcttagtc gggcaaatta 55740 aaaagttctg tgataacttt ggctataaag cttggattga cccgcaaatt aacgaaaaag 55800 aagaattatc aagaaaagat tttgatgaat ggctttctaa gttagaaatc tattcaggaa 55860 ataaaagaat tgaaccgcat tggtatcaaa aagatgcagt gttcgaagga ttagttaatc 55920 gtcgtagaat tcttaatctt ccaacatccg ctggtaaatc tttaattcaa gctttgcttg 55980 cacgttatta tttggaaaat tatgaaggta aaattcttat cattgttcca acaactgctt 56040 taacaactca gatggctgat gactttgttg actatcgttt attcagtcat gcaatgataa 56100 agaaaatcgg tggtggagca tcaaaagatg ataaatataa aaatgatgca ccggtaattg 56160 ttggtacatg gcaaactgta gtaaaacaac caaaagaatg gttttcccaa tttggtatga 56220 tgatgaatga tgaatgccat cttgctacag gaaaaagtat ttcatccatc atatcaggtt 56280 taaataactg catgttcaaa ttcggtttgt ctggttcatt acgtgatggc aaagccaata 56340 tcatgcagta cgttggaatg tttggtgaaa tatttaagcc agtaacgact tctaaattaa 56400 tggaagatgg gcaagtaact gagttaaaaa ttaatagtat ttttcttcgc tatcccgatg 56460 agttcactac taaattaaag ggaaaaactt accaagaaga aataaaaatt attactgggc 56520 tcagtaaaag aaataaatgg atcgctaaat tagctattaa gcttgcgcaa aaagatgaaa 56580 acgcttttgt catgtttaaa catgtatcgc acggtaaagc tattttcgat ttaattaaaa 56640 atgaatacga taaagtttat tacgtatcag gggaagttga taccgaaacc cgcaacgtaa 56700 tgaaaacctt agctgaaaat ggtaaaggaa taattatagt agctagttat ggtgtatttt 56760 ctactggtat ttcagttaaa aatctgcatc acgttgtttt agcgcacggt gttaaatcaa 56820 aaatcattgt attacaaaca atcggtcgtg tattacgtaa gcatggttct aaaacaatcg 56880 caacggtctg ggacctcata gatgacgcgg gcgtcaagcc aaaatctgct aatacgaaaa 56940 agaaatatgt tcatttgaac tatcttttaa aacacggcat tgatcgtatt cagcgctacg 57000 cagatgaaaa atttaattac gtaatgaaaa cagttaattt ataagggctt cggccctttg 57060 gagaaaaaga tgttactagg atttaaacaa tttctttatg aagcttctat tgatgaattt 57120 atgggtaaaa ttgcctcttg tcaaacatta gaaggtctag aagaacttga agcttattat 57180 aagaaaagag ttaaagaaac tgaattaaaa gatactgatg acatctctgt gagagatgct 57240 ttggcaggaa aaagagctga attagaagat tcagacgatg aagtagaaga aagcttttaa 57300 attaaaaaag gcccaaccaa aaaggaaggg ccaaaactat agactaaagg tcacactata 57360 gcaaaagttg tgtttcattt aattgttctt ccgaactttc tgaaactggt agttctttaa 57420 tgtaattata gcaaggccca ggatgtacag gacctttgtc tgtttcaaca accaatgcag 57480 aatcgattgg agttttacag acaacacaaa tcttatctga catgattgtc tccttttgaa 57540 tatagtaata tttataaacc cattttaatc cgcatttctt gtacacggat taagcaagct 57600 tccatctctg ctaatagtcg aaatacttct ttataatctg tcatatttac cccatatctc 57660 tcatatgcat atcaatgccc atatctttag aataaaaata ttcatcaaga tatccggcaa 57720 attttccttt aatataaagg acatcttcac cacacgggtg gtcggccagg atacgaatat 57780 cctgacgctt aagattatgc tttttcatta agaattgaat ctcagtttca aattcttctt 57840 cataattaaa agcatcatca atgctatatc tcattatttt ccagcctcaa atgcccgcat 57900 gtcttgaata tgcttaatag caaatcctcg tgatttgata gcatcaagag ctccactaca 57960 gaaatctaat aaaatccccc aatactgcag cgaggtatca acctttaaaa catccttatc 58020 agctgataga actgtcttca tttctgattt ctcgtaacga tccatactaa attcatcacc 58080 atctcctcgt cccgagtagt agtctaatct agctttaaga gcaacttttt tctgtgcgtc 58140 aattctaagc atttcctttt taatacttga atgcttatta agccatttac tatataacat 58200 cacattatta gctgcttcat actgtaattt agtcgaatct ataaacacat ctttcttcaa 58260 ttcttcttga agatcttcta atctcatatt gttctctatt caattgttat tggatggact 58320 tagattcatt ataccacgtt ttaacgtgaa gcattatacc ctattactcg aagccagttg 58380 cagttttatc tgctcaatat catcagggtt atcgatgacc gaaaagcgta tttctactat 58440 cagagtataa tcatcataaa ctggtatcac attaactgat aatttatcaa tacgtggctc 58500 atagtttctt actgcgcttt cgatattgcg ctcaactgtg tcagcagtaa gaggagtcat 58560 attttcaaaa agctggtctg ataaatcaca tccaaattca gggtcaaacg gtcttgaacc 58620 ttttcttgtt gtaataattc ccaaaagact gtttttaatt gaccttaatc caagtgatct 58680 ggaaacatct ttgttccaat ccattttcat ttccgggtca atatcagaat aaagcttatt 58740 aatatttgcc attatagtaa ctcaaagaac tctttgaggc ctcttattac atgagcatgg 58800 gtttttccac actctggaca tttaattgga acagccaaat aaacggtagg ttttaaaagc 58860 atatctttta tagctacaat atctgactct gtgatgatag aatataaatc ttctagttcc 58920 ttttcattta agtcttcaac tggaatgctt tccccgttag catgaatcgt ttctatgcat 58980 gatactatca tgtgggctat atttttatca tcaaaaattt tagggtatcg gaatttaatt 59040 ttaatgtcac ccagtgtata ccagaggtct tctggtgcat ctatttgtgt atgtaataga 59100 tttatatggg ttggtatttc agttccacag gtgcacttcc aggagttttc gtgattaact 59160 tcaccgagag aatgtgccca taaatgaatc agcagtagtt ctgattcttg gcggtttaaa 59220 tcttttgcat ttgtgcagtc tttgattagc tttttaacaa ttacttctac agaaccatta 59280 tttttggcag taataagttc tagatattct ttaagcgtga atgcgcgaca attgattatt 59340 ttagaaccaa ctctcacatc aaatttgtat tcatacatat ttagctcctt tatttatcat 59400 atttataaat agaataaaag gagcatctat ggcaaacatt attcgttgta aattaccaga 59460 tggtgttcat cgttttaaac catttacggt agaagattat cgagattttt tgttagttcg 59520 aaacgatata gaacatcggt caccacaaga acaaaaagaa gtaattgctg atttaattgc 59580 tgattatttt ggagactatc cgaagacttg gcaaccattt atatttttgc aggtatttgt 59640 aggatcgata ggtaaaacta aagtaccggt cacatttgta tgtccaaaat gtaaaaaaga 59700 aaagacagtt ccatttgaaa tatatcaaaa agaattaaag gaacctgttt ttgatgtagc 59760 taatgttaaa attaaattaa agtttccttc tgagttttat gaaaataaag caaagatgat 59820 tactgaaaat attcattctg ttcaagtaga tgaaatatgg tatgattgga aggaaattag 59880 tgaatcaagt caaatagaac ttgttgacgc catcgagata gaaacattag aaaaaattct 59940 cgatgtaatg aatcctatta atttaactct acatatgtca tgctgtaata agtacattaa 60000 aaaatacact gatatagtag acgtgtttaa gctattagtt aatccagatg agatatttac 60060 tttttatcaa attaatcaca cactagtaaa aagtaattat agtttaaatt caataatgaa 60120 aatgattcct gctgagcgcg gattcgtatt aaaactgatt gagaaggata aacaataatg 60180 agtatgttgc aacgcccagg atatccaaat ctcagcgtta aattgtttga tagctatgac 60240 gcttggagta ataatagatt tgttgaatta gctgctacta ttaccacatt aactatgcgg 60300 gattctcttt atggccgaaa tgaaggaatg ctgcagtttt atgattctaa aaacatccat 60360 acaaaaatgg atggaaatga aataattcag atttctgtag ctaatgcaaa tgatattaat 60420 aatgttaaaa cacgaattta tggatgtaag catttttccg tgtcagtaga ttcaaaaggt 60480 gataacatca ttgctattga attgggaact attcattcta tagaaaatct taaatttggt 60540 agaccatttt tccctgatgc aggtgaatct ataaaggaaa tgcttggcgt catttatcag 60600 gatcgcacat tattaactcc agcaataaat gctataaatg cttatgttcc tgatattcca 60660 tggactagca catttgaaaa ctatttgtca tatgtaagag aagttgctct agctgtagga 60720 agtgacaaat ttgtatttgt gtggcaagac atcatgggag ttaacatgat ggactatgat 60780 atgatgataa atcaagaacc atatccaatg attgtcggtg agccatcttt aataggtcaa 60840 ttcatccaag aattaaaata tccattagca tatgatttcg tttggttgac taaatcgaat 60900 cctcataaac gcgacccaat gaaaaacgct actatctatg ctcattcatt tttagattct 60960 tcattgccaa tgattactac aggaaaggga gaaaactcta ttgtagtgtc aaggtcaggt 61020 gcttattctg aaatgactta taggaatgga tatgaagaag ctattcgtct tcaaactatg 61080 gcgcaatacg atggctatgc taaatgttct actgtcggta attttaactt gacacctggc 61140 gttaaaatta tttttaatga tagtaaaaac caatttaaaa cagaatttta cgttgatgaa 61200 gttatccatg aattatccaa taataattca gtaactcatc tatatatgtt cactaatgca 61260 acgaaactgg aaacaataga cccagttaag gttaaaaatg aatttaaatc tgatactacc 61320 actgaagaaa gtagttcttc caataagcaa taaagaagtt tctattccta aaatgggtct 61380 taaacattat aacattttaa aggatgttaa aggtcctgat gaaaatttaa aacttcttat 61440 tgattctatt tgtccgaatt tatcaccggc agaagttgat ttcgtttcta ttcatttatt 61500 ggaatttaat ggaaagatta aatctcgtaa agaaatagat ggctatactt atgacattaa 61560 cgatgtttat gtgtgccaaa gattagaatt tcaatatcaa ggaaatacat tttattttag 61620 acctcctgga aaatttgaac aatttttaac ggtgagcgat atgttatcta aatgcttgct 61680 taaggtcaat gatgaagtta aagaaattaa ttttcttgag atgccagcat tcgttttaaa 61740 atgggcaaat gatattttta caactttagc aattcctggc cctaatggtc caataactgg 61800 aattggcaat attattggat tatttgaatg aaaaagccac aagaaatgca aacgatgcgt 61860 agaaaagtta tttcagataa taaaccaaca caggaagcgg ctaaatccgc ttccaacact 61920 ttatctggac ttaatgatat atctacgaaa ttggatgatg ctcaagctgc ttctgaacta 61980 attgctcaaa ctgtcgaaga aaaatcgaat gaaataattg gagcaattga taacgtagaa 62040 agcgcagtga gtgatactac tgccggttct gagttaattg ctgaaactgt cgaaattggc 62100 aacaatatta ataaagaaat tggtgaatca ctcgggagca aattagataa attaacaagt 62160 ttactagagc aaaaaattca gacagctgga attcaacaaa caggaactag tttagctacg 62220 gttgaaagcg ctattcccgt taaagtcgtt gaggatgata ctgctgaatc tgtgggtcct 62280 ttattaccag ctcctgaagc agttaataat gatcctgacg ctgatttttt ccctacccct 62340 cagccagttg agccaaagca agaatcacca gaagaaaaac agaaaaaaga agcatttaac 62400 ttaaaattat ctcaagcttt agataaatta acgaagactg ttgattttgg atttaagaaa 62460 tccatttcaa ttactgataa aatatcaagc atgctattta agtataccgt cagtgctgct 62520 attgaagctg ctaaaatgac tgcaatgata ttggctgttg ttgttggaat agacctgttg 62580 atggttcact ttaaatattg gtcagataaa ttttcgcagg cttgggattt gtttagtaca 62640 gactttacta aattctctag cgaaaccgga acatggggtc ctttattaca gagcatcttt 62700 agttctattg atgaaattaa aaagttctgg gaagcgggag attggggtgg attgacagta 62760 gctattgttg aagggcttgg aaaggttctt tataatttag gagaacttat tcaattaggt 62820 atggctaaat tatctgctgc aattcttcga gtcattcctg gtatgaagga taccgctgat 62880 gaagtagaag gaagagcatt agaaaatttc caaaattcta ctggagcatc tctcaataaa 62940 gaagaccagg aaaaagttgc aaattatcaa gataaacgaa tgaacggaga ccttggtccg 63000 atagcaaaag gattagataa aattgctaat tggaaaactc gtgcatctaa ttggattcgc 63060 ggtgttgata ataaagaagc actaactacc gacgaagaac gtgcagcaga agaagaaaaa 63120 ttaaagcaac tttcacctga agaaagaaaa aatgctttaa tgaaggctaa tgaagcacgt 63180 gccgcgatga ttcgttttga aaaatatgct gattcagctg atatgagtaa agactcaacg 63240 gttaaatcag ttgaatctgc ctatgaagac cttaaaaaac ggatggatga cccggattta 63300 aacaattcac cggcagttaa aaaagaactt gctgctagat tttctaaaat tgatgctact 63360 tatcaagagc tcaagaaaaa tcagcctaat gccaaacctg aaacttctgc taaatcgcca 63420 gaagcgaaac aggtccaggt tattgaaaag aacaaagcac agcaagctcc tgttcagcaa 63480 gcatctcctt caatcaataa tactaataat gttgttaaga aaaatactgt cgttcataat 63540 atgacacctg tcacaagcac aactgctcct ggtgtatttg atgcgactgg agttaattaa 63600 ggaataatat ggcaattgtt aaagaaataa ctactgattt aattaaaaag tccggtgaga 63660 aaatttcagc cggacagagc actaaatcag aagtagtaac taaaacatac actgcccagt 63720 ttccaactgg gcgtgctagt ggtaatgaca ctacagggga cttccaggta acagacctat 63780 ataagaatgg attattattt actgcataca atatgtcatc tagggattct ggaagtctta 63840 gatcgatgag atctaactac tcttcttcat cttcgagtat tttacgtaca gccagaaaca 63900 ctattagtag tacagtatca aaactatcaa atggattaat atcaaacaat aattcaggaa 63960 caataagtaa agctcctgtc gcaaacattc ttttaccgag atctaaatct gatgttgaca 64020 catcatcaca tagatttaat gatgttcaag aaagccttat cagtagaggc ggaggtactg 64080 ctactggtgt gctaagtaat attgcttcaa ccgcagtatt tggggcactg gaaagtataa 64140 cacaaggtat aatggctgat aataatgagc agatttatac gacagccaga agtatgtacg 64200 gtggcgctga aaatagaact aaagtgttta catgggattt gactccacgt tcaacagaag 64260 atttaatggc tattattaat atctatcaat attttaacta tttttcttat ggtgaaacag 64320 gtaaatctca atacgctgct gaaataaagg ggtatttaga tgattggtat cgttctacgt 64380 taattgaacc tttatctccg gaagacgcag ctaaaaataa aacactattt gagaaaatga 64440 cagcaagttt aacgaacgtt ctagtagttt caaacccgac agtttggatg gtgaaaaact 64500 ttggtgcaac atctaagttt gatggaaaaa cggaaatatt tggtccatgc caaatacaga 64560 gcattagatt tgataaaaca cctaatggta actttaacgg attagctatt gctccaaacc 64620 tccctagtac atttactctc gagattacta tgagagaaat tatcacgtta aaccgtgctt 64680 ctttatatgc ggggactttt taatgtattc tttagaggaa tttaataatc aagcaataaa 64740 cgcagatttc caacgtaata atatgtttag ctgcgttttt gcaacaactc catcaactaa 64800 aagctcttcg ttgataagtt caattagcaa cttttcttat aataacttgg gcctaaattc 64860 aaattggtta ggattaaccc aaggtgatat taatcaggga attaccacgc taattacagc 64920 tggcacacaa aaactgataa gaaaatcagg ggttagtaaa tatcttattg gtgccatgag 64980 tcaacgtact gtccagagtt tattaggctc atttacagtt ggtacatatt taattgactt 65040 ctttaacatg gcatataact catctggatt gatgatatac tctgtaaaaa tgccagagaa 65100 tagattatcc tatgaaactg actggaacta taattctcct aatattcgta taactgggag 65160 agaattagac cctttggtta tttcatttag aatggattca gaagcttgta actatcgtgc 65220 aatgcaagac tgggttaact ccgttcaaga cccagtaact ggattgcgtg ctttgccaca 65280 agatgtcgag gcagatattc aggttaatct tcattctcgt aatggattgc ctcatactgc 65340 ggtgatgttc actggatgca ttccaatatc agtgagcgct cctgagttat catatgatgg 65400 agataaccaa ataactacat ttgatgttac ttttgcgtat agagtgatgc aggctggagc 65460 ggttgatagg caagctgcgc ttgaatggct tgaatctgct gctataaatg gtattcaaag 65520 cgttctcgga aatagtggag gtgttactgg actatctaat tcgctttcac gacttagtag 65580 actaggagga acctcaggaa gcatttcaaa tattagtata ctatgacagg gattgtcaat 65640 tcgcagagta aaatattagg agcaatataa caacggggac ctttcggtcc ccatattttt 65700 atttgcggaa tgaaatgaaa gcagaaactg aagcaactaa actgtcttca atataaactt 65760 caatttttac cggagcttct gactcaaatt tacctgttac tacaccctga aaaatacttt 65820 cagtctgttc tggctttgaa aaattttcag aaggaaaaat tccgaacttt ttatctgttc 65880 caaaaatttt aataaattca tcgtaaaccg cttcgttaaa agcattatca gcaggaataa 65940 cgccttcaac tacaagttct tgacctaaaa agcgtaaaga agatttcatt ttgtgttcct 66000 catgttatgt cagtaagact actataacac aacacgaggg acttgtaaac tacattttga 66060 actttttagt acgcgtaata ggcatgcgtc gattttatac tgtttcattg tttgaagagc 66120 agtatcaaaa acagcattaa tgacaccaat tggatttcca cccaagtttt taagcttaac 66180 taatgatagt ttctcattaa cacctatcat tacgatatgc atcattttgt cgcctggttt 66240 aacgtttttg tttgtatcac cgccagaggt gtatgtacaa aatctaaatc caggaagcac 66300 gctttcttcg ccggcttgaa tagcaaaaat ttgtggtatt ttatgcttag gatttaagtt 66360 aacaaccggc gccgaagcgc cgtcaaataa ttatgtaata agttccatga tttatccttg 66420 aacgaacttg taaggcatgt ttgcaatatc tatgcaagac gcaataattc caagagatga 66480 ttctactttc tgtttaacat ttgatgaaac aaatgatgca aagtcaactc tgtcttctat 66540 ttcaatatca cctgtcattg caactacttc accagtttcc attagacggt caccgtcata 66600 aattactgat tcggtgagtt cttccgtagt cataacttca gcttgaatga gttttgtatt 66660 attaaatgtt gttccgtcat tattagaagc atcagttatt ttattaactt tgaccatcaa 66720 tccacgtggt agaataactt cagcttctgt tgctattccg agacttcctg gatatacaac 66780 attaacttta tgagctccat caattgccca tcctatttga actttaacgt attcaggatt 66840 ttctttatac gctcttattt cgtttggatt aatagttatt ccttcttcat ttttatcaac 66900 tgtcaattca ttacgagctt ctggttctaa aagaccgata ccagcatgtg taattccaaa 66960 acgtccaaaa atgataggag ttaaagaagt agatacaaaa tttctgaaat agaacacttt 67020 atttttaact aatgcttcgt atataggagc agtcatactt tgagcacgat aaactgtaat 67080 gccttctggt atacggtcac cattttcaaa agctgaatct aaattattta tcgcagattc 67140 aatttctttt tcactcatta catcatatcg ttctggattg tagcggccta aaagaagatt 67200 attgatgtca gtatatcctg atccacaata ctctctaatg ccgcgctttt gcgatggagt 67260 atatttagaa ccatcacggg caatagtaat atcaatcatt ggacctgcac caattccaga 67320 aaaactataa atcattcttt tgaggaattt agtttttgct gcgttccaag aatttttagt 67380 tatttcttcc cagacatcat ctggctgtcc tttacgggtt ttattatgtt tatcaagcca 67440 attatcttta tattcttcaa agaattgatt aacagctgct gcgtatttct ctaaacattt 67500 tattgaagta gttggttcat ttttaatcgc attaagaatt acatctttaa ttttttcaga 67560 aacttcacca acctcactca ttggaaagaa tttatagtca taatgaagtt catctgcagt 67620 tccttcagca ataatttttg ctgccttagt tttagaagct attgaattaa ttccaagttt 67680 catttcttct gcttcgggaa ttaaaggagc tgtagcaggt ttattgaaat tagctgcagt 67740 agattcatac ttttggaata attcactttc aaatctagaa gattccaatg actgactttg 67800 tgcaattgct ctacgggaaa ttttaacttt aacgattaca gcttggtcag aacgtttatc 67860 gttttcttgc gcaatagatg ctgcaattgc ctcgttttta gttacttgag ctccagtatc 67920 tttattgata taaacatcac cgaccttcga ttcaacttta gtaaagagct cggtactaat 67980 ttccggaact cctggaatgt cttctagtga tacatttttg cgatgtataa gaatatatgc 68040 atacttttta tcataatccc agagttcctt aagaaggacg tatctgccac ctgaacgact 68100 acggataagt ctatcagcaa taacttgaat ttgtcgagct tgaccagcgg ttttagactt 68160 aagaatacgg agcatacagg catcaatttt atactgacgc atcgtccgca ttgcaacagt 68220 aaaaaccgaa ttgatataat taattgggct tggaccaaga cctttcaatt tagcaattga 68280 acctttagcg gttaatgtaa aaggaacaat atgcatcatt ttatcgccca tctttaaatc 68340 acgattagta tcacctccag atgtataggt acataaacga aagcctggtt gttcaattgc 68400 gtcatcaaca tgaactgaaa aaatttgtgg tattttcttc tttggattta agtttgtaat 68460 tggaagagta gtatcttcgt caaataattc tgtaattagt tccatcatat cctctctagt 68520 gtttattcta tttataaatt aaaggcccga aggcctttaa taatctaatg gtaagagagt 68580 acgatatatt tcaaactttg gccctttttc ataggcatca aatgtttctg taaatttatt 68640 ataagcgtat gcatctacaa attcgagaat gacttgtgat acagaagtag aaacatctcc 68700 accttctttt tgagctacaa caattgtttc taagtaagct ttcatagacc agttacctca 68760 tgaaaatcac caaatacatc ctcaaatgta ttagctttag ttttatcttc acgtaaacga 68820 atcgcaatcg gaagaaataa tttaacgtaa tcagtgcggc catcagattt taaccaaccg 68880 ttgcattcgc actctagaat ttttccaata taataatttt ggttttccat aatgcgagta 68940 cggtcaagtt catgcgattt tacaccagct ttatctttta aacctgaacc agcattgact 69000 ttaatttttc cacactctga ttcaagaata aatccacccg ctttagtagg gtctttacgg 69060 tgaggataaa ttcctacaat ttttaaatca acatcaatta cttctttaaa tttatagaga 69120 ttttttgaac gagtattttc ccataatcca tcgatatttt tgagaataat accttcaaga 69180 ccctggtcaa tatacttttt ataaattacc ttagcttcat ctaggttatt tactagctgg 69240 ttttcaatta aaattacttt atcatatcct gatgtcattt gttctagttt agaaaaacgt 69300 acatcatatt ttaaacgaaa cgccggaaga ccgtatattt ctaccaatgg gacataatcc 69360 cagacctgaa acttcatgca ttgagcttct ttttcagaaa tggttccctt taaagattta 69420 ttagcgattc cattagaagt agtacgtgat tcagctactt cggcgaattc tttggcttta 69480 ctaatttcag gataagcatc aaaaagaaaa tctaggcctt ctggctcctt tttaacttgc 69540 tcatggtata ccaattcgcc atcaattaac acgccttctg gatgaatctg gcgggcttca 69600 gcggtcattt tgattaattc ttccttaaga agatctaatc ctagatattc attaccggct 69660 cgtgataaaa gacgaacatc atctaattca tcacctctga cttcggcaaa gcaccgagcc 69720 ccatcagctt ttaactgggc aaaggctgga aatttgatat tcttattaat gcctttttca 69780 tcataagaac ttgcaagcat ttgaggttgt tcaggaatta aacctggcca aactttgttt 69840 gcaatagata ctgaagcacc gcattcaagg tctcgcatca tcacccgacg caaaacttca 69900 acatcatctt ttttaccatc ggtgatatat ccagttaatt cctcaattgc tgcatttcca 69960 gtcaatttcc gagtagctaa tgtgaattca atgaagtcaa gcatatcggt aagagtcaac 70020 attccaaaac tctgggtagt aataccaggt ttaggccatt tcttgatata atattgtaac 70080 ccacgagaat aagtcagacg atatactcgt ttaagcaatt cattatcttt attcttttca 70140 agaattgctt gcttctgctt agttgaacca atagatgcta tttcgttcag aattttaaga 70200 atcattgttc atccttcaga gtttggttta cagctctatt ataaatcaat tcatcattaa 70260 gctcagtcaa agacttatga tatgtggttc taactttatt tccttgcatc cagtgcttga 70320 tataaatgaa accttgctct acgcattttt taaaaattcg ttcgtctttt tgagctcgga 70380 attctggatt gcatctaaaa aattgattta cgtgaccgta atcacgtgta gtattacctt 70440 cattttcata aatagtgtga acaacaaaca ttagaatgct ccttggaaaa tattatcacc 70500 acaagtaggt ctattataca aatactctat accgccgggt ttaatatagt tccatgtctg 70560 aaacggatgt gtctgatatg gatgatatag atgattataa ggattaaatc caggagttct 70620 ccaggtagtg ttccaacgaa aagaatcgtt tttaatcatc ttttcaatta catcttttat 70680 agctttttca ctatcaaaac tttctttatt ttcctttggt gaaaaaagct tattctctac 70740 atcgttccat gtataaactc gctgagcagt ttttggaata ctgtcacgtt cccctcgagc 70800 catccaataa actggaacat ttaatatttc actcgcatga tcgcagtgat gagcgagatc 70860 gtcaatataa caaattacgt tatatttctc ttttgccttt ttgaacagct cttcttttga 70920 agaatcatga ccacacatca ttacttctga gaaggcacca ggaaaaagag cattcaaatt 70980 aaattgacga ttcaacagag cgtcaataga atcacccagt gctgtaacag ctacaaaatt 71040 ataatcttct tttaatttgt taattacaca cagagcatct ttatatggag acaagtaacg 71100 aataaaatct gaacgattgt atttttcaat taacttgaca ccaagttctt catcacaatt 71160 aaagagttta cctggagaaa taaatttctc atcttggatc atttttaaaa tatgttctaa 71220 tggaagatta tatttctgag caaaataagg aagacctgat tgccagctta aacatactcc 71280 atcaatatca gttaaaatag taggcttcat agagagtctc ttaataggtt taacacatca 71340 ataaattcag cttcggttag tattgtatca tcttttgtta gaccactagc catgctgtgc 71400 ttcaaaactt ttcctttcga ggcttgtaat gcatcacgaa agcccttgtt ttgaatcgct 71460 gcttcaaaat atgcatttgt gtataattct ttccacgccg gggagtatct tgaaaacgga 71520 actccaagcc agaagagggt cccacggtcc tgagctctag cataagacct tccagcttgt 71580 tgagcggcaa gcccggataa cccaaatata cgacgttgtt gttcaacatt tttcaccttg 71640 cacccttgga ggaatccttc aagacctcca aattgaatac catccataac gaaaggccat 71700 tgggcgaaat tacttaatgc acatgatggc cacctaaaat tgcttctaat ctctaactca 71760 gacattttca atgcttataa tttcaacatc agcccaatga ccatagcaag gaagacgaaa 71820 ttcaactggc cagttagggt ccttttctaa tataatagac ttaacttgcg gttcttcatg 71880 ttcatcagta tatggatttt tatccgttac tttatatgtg accttaatgt actgaattcc 71940 aaaaatctta ttaattatat tcatactaat tcctttaatc cgtaaatagg agataattca 72000 tcacccatac gaaggtcttc atttccatct acccaggaaa caatataagc ctcttttatt 72060 tgaataccac tccatttaaa tggaggtaga accttagaaa ttaatccagg tataccaact 72120 ccctttaatt caacagtttg acctaaaaag aatttcatta gaacctcatc tgaaagccat 72180 gtgatttaac attaccgccg ccaatatcag aaatgttaat ttcacgcgca attgaagggt 72240 caatgtcaat ttcacgattg agtttagcga tagctaaagt atcgcgccca tttacagtac 72300 ggaactctaa aggacagact acattaacat agtttttaat cgattcactg gtaggttgca 72360 aatgagcagg aaggtcttta ggcgcctttg agaaaaccac ttcacagaaa tttttgcggg 72420 tgtcaaaata agtagtcata aacatagtat tttcctcaat agggggccga agcccctgtt 72480 ttattttaaa tatcaaattc gttaagaact acatcaaaga ttgcttcaag atgctcaggt 72540 ttagctctgt tactcaaaat atgacgaatc caagttttaa ccagaagctt acgattgacg 72600 ccattccagc aaggatgagt acctaaatca cgttgacgga aatcatcatc taatgcgatt 72660 ttaaaagaag aaccttcttt cgtgattgaa accgtgatgc cattttcaaa tcgcatataa 72720 acgtaattag gagtcatata ctgttcaatt tcgcatactg atccattttg atgtttccaa 72780 aggcagatag tatcaataga acctgcaata ccgttagaaa catatttacg ttcaaagttg 72840 atgtagttca tttttattct ccgagatgtt taattgcggt acaggtatat aatatcatat 72900 cctgtaccaa agtaaacaat tattttacta ctttccagtg ctgcatgtca agtttaccaa 72960 cttttttcat cttctcaatt aagcgttcgg cacgttggcg cgctgtaaca taataccatt 73020 cacctaattc attttgttca atttttccaa caattactgt attcaattca taaatccaac 73080 cagtaaagaa attatgaact tgaattgtaa aggtgaaatc tgttcccata ccttctgttg 73140 tttctacttc aataatatca ccttcaactg ccattaagaa ccacatagtt tcatcatatt 73200 taccattgaa gcatttagtt ttaactgtag cgttcaaatt aatcgttttc attttattct 73260 cctttgtttg tgtaagataa tactatcaca aaggaaccgt actgtaaaca actttgtgca 73320 atctttggaa aataaaaaag gactcccgaa ggagtcctca acttatgctt tctgcttacc 73380 aaaacgagaa gcatcatctc gaagaaccgc acgtgctcgg cgcatgatct tctcaacagt 73440 ttgattgata cgagagttcg acccacgctt gtaaccagcg cgtttagaat caccaacttt 73500 cttttcaact gctttctttg ctttagcttg ttttgccatt ataaattctc ttttaaatga 73560 aaatgcagga cttattggca ttgcctgcgc aagccctcaa ggggaacata ggtttttgga 73620 tatttaacga ccaggataac cataaacccg tcatcattca cattcaagag gtacaccgta 73680 aaactgccgg ggtcttaaaa ctataatgat tcgcaaatca ttaatcagac agttcgacgg 73740 ctcctcgatt ttagctcaca ctaaggcagt gaatctccag taaattactt cagtgttacc 73800 acaaagtgac gaactgcttt tcgtgcagca gaagccagag gcttagcata tttaagttca 73860 tctttttcct gaagctcagc agctaatgca gtttgagcag gattcagatg tttgaaataa 73920 cgcaggattt caagagcttc ggcttcaaca tcaatagatg cgccatagtt ttcgtgacca 73980 ttattccatg cgtttcgttg cagttcaaga gcgtgttgta gttgtttaat catttaaaaa 74040 ttctcgttag agattaaaac tcggtagtca cgttcttctg aatttcatct tctttcgaca 74100 gatctctcag ttgtagacta ccacgtagaa ttgttcggtt aacttattat tccgacaccc 74160 aattcatatt attatttata tcacttataa agacacggaa tagctttata gtgacaagtg 74220 acgaattttt gtttaatttc ttttggctgc ttaagaccca gagctacaaa aggatgcgga 74280 acgtttcgaa tttgaccaac tggcagagaa gtcaaatcac caacttcgca gaaaccttca 74340 ggaacatcag gaccaacaga gtgaattaca cacagttcag gaacttcacc ttgaacacgt 74400 ttaccgataa taagtcctga ttctgtaact tcttcatcac cggcttgtgc aggttcagaa 74460 actaaaataa catattcacc tacagcacga attggtagct gttgtacttc agacatcgtt 74520 tttccttttt gttaacagat gagttaataa taacaaataa ttcttaaagc atttatttac 74580 caataaattg aagcaaatgc tcaactttca taccattaac ggaaatcaat ttatcaatag 74640 aaaaacctcg ccatgcaccg agttcaacat caaataccgg aatcatatca gtagattctt 74700 tccgagcaca ttcagtcaat ttaccagttt gcatggttgg cataaagtcc gcatcacgag 74760 tgcctttcat agtacgaata gtaccatcag acttttcaaa aactacgttt gaaaccccca 74820 tggacaattt agttttcaaa atttcacgaa ttgctacttt ttgttcagtt gtcagtttca 74880 tttatttacc tattacagtt ttaatatgag ttgttccacg ttctttaaga gtggaaagca 74940 atttttggca tttttctaaa tcagatttcc aactatacgg cctatcaatg caaacccatt 75000 ctgacttata atactgtttc catttagaga aaaaatattt cttatactct acagcaaatg 75060 aaatgttctc gttagaataa gaactaattg ctgtgagctg taccaaacga aatttcatta 75120 ttcaccacag aattcgttga tattttccca gtttaactta ttcaagtttt tcttaggaac 75180 attaaacact tcaatacccg catttcgcag aatatcatcc cagccaggtt tatttttatc 75240 gtatgtttcg caataaacca gctttttaat tccagattga gctattgctt ttgcacaatc 75300 tgggcaagga gaaagtgtta catacatagt agcaccttca attgaagaac cgtttcgtgc 75360 agcaaacaaa atcgcattta gttcagcatg aatttcattt ttagacgacc attcagagtg 75420 agcactacga tgttctttcg ccaagacaaa acgatcagtt gaaccaaatg atacgcattc 75480 aggcttatga ccttgaatga tagtatgttt aggcttattc aacaaccaac cttgctcagc 75540 agcataatca cagcagttca ctccccctgc gggtgaacca ttatacccag tagaaataat 75600 acgtccattc ttttcaatta ctgctcctac cttccaggag caacattttg attcctgcga 75660 tactaaatat gcaatttgaa gtactgtact cgctttcatt tcataatcac cagataagca 75720 gatttagcag tttcaacacg ataaatttcg tgacgaagtt tagttatact tttaataaca 75780 gaactaatta tattctgccc gtctttaaag cggtttttct tatcaataaa aactgcgcca 75840 gtcatctttt tgtgaagctc aactggatac ttcgtcacaa taatagcatc atacacagaa 75900 ggatgaatac tattcaccag agtatcattc attaaagtta ttctaatgaa ctttgctgtt 75960 tcagaatcaa gcgctctatg atcaccagta tcattttcaa gacaattatc aattatatca 76020 gttaaattca tcatagtacg ccatacaccc tttgtgcttc aactaatcca tcaaaatcca 76080 gtttaagatg cgatatttga tcgccatcac ctggattcac aattactaat actgaacgag 76140 gagtttcggt aataacacga accgatgttt caggaaatcg ttcagaaacc ttatttacta 76200 attcctgtgc aaatagttta actttttctt ggaattcttt aacagtaatt ggtttttcac 76260 ttagcatgtt gatcccagct ccttactttc aacgttttta actaatttga cagaaactaa 76320 ttcagcatct tgagtaatca ttaccggacc ttcttcatac tcttcaagat attctagagc 76380 tttcttttta gcttcttcct tcgtatcagt ttgagcatag atataaaaca tacaaccagt 76440 aatacctact actttccact taatttcttt atcagcttta atttcaaatt tactgacaga 76500 atcatctttt tgaacttctt cgaaaaaaga atattctaac atataagcaa ttgaaaataa 76560 cgggctatct ttataggatt cgcccattac atcaatagct ttataccagc agtcatcaat 76620 tttgcgttta atgctaataa cattctttgc agggtcaatt tttactttaa atgaattttc 76680 cccaataaac tgggaaattc gtttattagc cccgcaagtt tcattaaaaa tatctttata 76740 tccagtttta aagcgataaa ccttatcttc ttcaaaccat tcgctcattt caatttcctc 76800 atttgttttg gtagagctat aatatcacaa ctctaccgta aagtaaacta ttaaatcgct 76860 ttgaattccg cagtttgaga ttcaaagcga atatcgcctt tgatgactag ctcagcatca 76920 agaccgaata caacaatgat atgcgcggaa cctggataca acgtgatggc aacagaatcc 76980 acctggtctg gaagcaaagt attcaataca tgagtcactt gagcgtggat tcgaagctca 77040 gctgcgttat caagtttttc aaacatatta ttagcgataa tttgactaaa cactacttct 77100 acgattttag agtaagtcgg aaacatattt acctcacata attttcttcg agccaattaa 77160 taatagtcca agtttcatgg tgccaagcca ttaaaaatct cccgaggcga cttgccagca 77220 ttcaacaccg atacgacgcc acatttctac tacttgagtt cggtcatcaa tagctaattt 77280 cacatcaaaa tgtggtgcga tgtgtttcca gaaaatttct tctttaacta catcatcttt 77340 acgggtatca ccttgttcgc gttgacattg cataactaat ggaacgccag caatatcctc 77400 aacccattta cgggtcatac gataatattt cgttgggtct tctttagttc cactttcacg 77460 acctgaaacg actacgattt gatacccttg cttatcgtac atcttggaca gttcaacaac 77520 catgggatta ataatatcgg tatcacattt ttcaaggtca taaggaccac gaccattcat 77580 ttttgctagt gtgccatcaa catcaaaaat aactgctttt ggtttaccag gagtcccttt 77640 atataccgga agaccgagat actctcgcat gcttttgtac attgagcgta aaatatcaat 77700 tggtactgct ttagttccac gttttgagtt acgtttaacc aattcagtcc aaggaacatc 77760 aaacacttta tattcaactt tccagccgta ttctttggca aaagtttccc atgccaggcg 77820 acgttcagga ttcaggttag tatctgaaat gattactccc ttaacagaat cgccaccgta 77880 cagaatattt ttagctgtat caaactgcat accagttacg ataccttctt tctttttggt 77940 atacttatac tcgtcacgtt cttcatgacc catgatggat tgacgataat catcacgatt 78000 gatattataa aacccgggat tcttagcaat aaattcacga gcccaagtac tcttacctga 78060 accaggacag ccaatagtca aaataatctt tttcatcatt taattcctaa gaaaacttca 78120 agaatacgaa tattatgctc acgccgccct ttatataatt cagctgttga ttgattcacc 78180 gatttactct gaacattgga tgaaataaat tttatcatgt gatttttaag ctgatacata 78240 tcaagcccac gagctttcgc ttcttttcgc agggctttac cagcgtcatc taaagcttta 78300 gcatgttcaa tgtcttcgct aatgcttgat gcactttcat gacatacatc aatgtaacgg 78360 tctgagcatt caatataacg ttctagaaga gttttcattt attttttctc aaccaatgat 78420 tgaatataat catgcaggtc tttagatgct ttaccccact tattttgata ttcatttttg 78480 agattagcac gtgattgagc taataaaaca tcattagttg gaggtaaaga ttctaaccgc 78540 tgaatctggc gtccataaat cattgcagcc atctcggatt cataaatcaa tcctttgaga 78600 tgttcaaatt gatgccgtga aatcatttac atttatcctc ttttaactct tgacgataat 78660 aacatatcat agttttctgg tcatgtacat atcgttttac atcattaagc caaatacgaa 78720 attcctggga atcttcaaat ggcataccga cccaagcttt accatcgata actttaactt 78780 gccaagatag tttagcttca tcatatgact ttatttgtac aggccaatta ggatgaactg 78840 tttctttctt tacttctaga ggctttgtcg aacaaccaac tagaagacca atagataata 78900 ttactgctga tagtttaatc atttagaaag gtcctggatg tcttctgcga acttgttgaa 78960 ggagttgttg atttgttttt caaccaatcc tggcttatga gccaccacat ccgccttctt 79020 tgcgtctttg cgcagttttt cattttcacg ctcaatagca gcaattgcct cacgattttt 79080 attattcatc gcatcaatat aattatactg aattcgcaaa ttatttaatg ctaaggcgtt 79140 ttcattggac gtttttgtaa tttctacaac agacgtttct aatctttcta ccttattttt 79200 taaaataata gatgttccgc caaatgctat tacaagtaat agcaatccag ctgtaaaatt 79260 acttacatgc ataaagtttt aataacctct acaatatcgt cttgagaaag accgttaatt 79320 aaaatatgat gttcagccgg agatttagaa attttaaagc atgcctcaac atcttctgcc 79380 atatccgatg cactacgatt tggattacta accccaaggc ggtgttttcc agtcaaagga 79440 ttaacgatga tatagcattt gcaattattg atatgaacat taggttgagt ctgattaatg 79500 aacacttcac aatcatattt cgcaagctga ttttctaaaa agactttcat ctcttcaacc 79560 gcatcaggaa gcatatcacg ggcttgctca agacgacgat ttcgatattc tttaatggtc 79620 gttttccgct tgacttgctt tgctaaatct ttcttaagat cggtgatata tccaactcga 79680 cgatttcctt tgaatacaga aatcccatct gtagtatcac cgtatgcttc aacgaccatt 79740 tcagtagtaa taagttgtaa atccatcata aagtcctcat gttatgtcag taagtctact 79800 ataacacaac acgagggact tgtaaacagc ttagtatcct tctgggataa attttttata 79860 atttttcaaa aaattctgtt cgatttcaca catgaccttc tcttgactat catacccttg 79920 gtagaggctc atgatgatac cgaacaggtg atccattcca gcacctttag caacaccttg 79980 tgcttccatt gcataggtct ttctatcctt accacaatgc ttattgtgac agtcaagaac 80040 taaaaacaga gctcggtcta agtacttcag ataagtcgtt tcaaatgctt caatttttct 80100 gtgtgaatat tcatcgtcag cgtacattgc tttaagatca tctgatgcac cgtcaataat 80160 agtcttaaac aatttttctg gattatctaa tgaacttttt gtgctatgaa gagacacata 80220 ccagtcagac ttaattttaa aatgagaacc atctttcatc acagcaacat agccttcgat 80280 gttttctgca tttttagctt cttctaccca tttaggacta tcgatttcgt atcgttcaac 80340 tagatacgga cgaagaatag catctttata aatatcatca tatgaaatgt attcacccgt 80400 ttcgttttca cgaacattca ataaaatgat tttcatctct tgataagcaa gaacgattct 80460 attcgtcgga gcgacgaatt cgaagttagc agtaaatcca tcttcggcta attctttaag 80520 tctgtcgcgc aactggtgat gattaatatt catcaaaatt ccattagcca ttaaagcctg 80580 ttcggatttg attgaaccct ttgatttgaa cagaatttca tcaccgtcta aataagttga 80640 taccaaagac ccatcttctt ttgttagaat gtaatcaaca tcatttaaat cgatattcat 80700 cgtgaatgga ttttcattca agttaaaaaa cttttccatg ggacgagagg caattcttac 80760 cggtttttct ccatccattt caaacataat tccacgacat tctaatgcgt ctggaagtaa 80820 ccaatcagaa taagatgcat aattatatga gaaaattctg taagttcttc cagatgcact 80880 tacatcatcc gagtaaaaaa acttacgctg tgaatcctta catagttcca ttaaattgtt 80940 aaaaagttct tgcattgtgt atcctctttt gtgttttgaa tatagtacca cactccatgt 81000 ggaagcatca ttttttcttg tgttgaatat tccaaggcgg gttaaacagt ttaatgaata 81060 gaggctcctc taggtcaatc gttgcgattg tcattgtacc taactcattt gtcatagaaa 81120 gattaaaaca ttggcgggcg taaaattcaa ctttgcttcc ttcctttagc gcagtatgaa 81180 ttaatgcaga tttagtagaa tcagacgttt tgtctttacg gttaatagca gttctataat 81240 agtttattct tttacgtaaa tttttagttt ttccaatata aacaagctca tcatttatag 81300 caatagcata aattacgtta tacttgtttg gaatagataa ttgttttata cttccgttgt 81360 cgtctaattc tagctcagta tatttaataa atgaatattc tgttgcaatt tctttcataa 81420 taaaatgggc cttgcggccc actccttaaa agtatttttt aaaactcatc ataactttat 81480 catcaacatc attatcaatc tgtgcaacaa ggtaagatga cagttctact tcttgtggcg 81540 cggattgaac attatcagaa ttaagatatt cacgaatcca aggatatgga tgtttaaccg 81600 gagcatcggt aattgggcat ggaagaccac actgtttcat acgagataca gttaagtaat 81660 caataaagct ccacatgcta tttgtattta atccaggaac atctccatct ttaaataaat 81720 gaactgccca atctttttct tggcggttaa cttccatgaa aatatcaact gcttcttgtt 81780 cacactcttg agcaatttta acccattcat caccatcagt accggattga agctgacgaa 81840 taatatattg ggtgccttta aggtgaagct gctcatcacg cgcaatgaac ttcataatct 81900 tggcattacc ttccatgatt tccatgttct tatggaagtt aaaggtaccg tatgttcgat 81960 tgagctcgct aattctcaac ccgttctctt atgaactgct gcatgttacc atgcagtcca 82020 gactatatca caatcccgga gggattctcc ccatttcgag tcgcttgacc ctacgtccga 82080 agactagtcg ttgaaccttg ctttgcaatt gtcgccgtgc catcgtttat atgttgatgg 82140 tgataaatct ttcttatcac aatatggaca attcaattga attctatttg gatttaattt 82200 aaatctatcc aaatttttct atagttcaat tgtgcatcct cttaaaggta taatcatatt 82260 ataccaatta aaggtgcaaa caaaaccttg gctgctagtt ttccatttct ggattttcca 82320 gcaattaaag gagttttcga taagcattac tgcttaaagg cgcattttac gcgaaagata 82380 cataaaaacg aatagcttcc aaggcgttga taacatgcaa acagaggtaa agagatttca 82440 ttagtgctcg tttagcttcg gcttcttgtt taatagctcg atttaaacga aaaacagcat 82500 caggagattc tttagctagt tctacaaatt ctttagcatt ttcccattca cgggttttaa 82560 ccaagacatc atcataatag cgaccgatag attcagcacg tttcatgata gcttcatcta 82620 atacaatctc atcaaatacc tttgacggat cagtataaag atttcgcatg atatgagtat 82680 atgaacgact gtgaatagtt tcactaaaag tccatgtagc aacccatgta tcaaggcttg 82740 ggtctgaaag caatggcata agtacagcag acggtgcacg accttgaata ctatcaagta 82800 atgattgata cttcagatta ttagtaaaaa tattttgttg atactgagga agcttattaa 82860 actgtgcagc atccatcatc aagtttactt cttcaggacg ccagaaaaac gagagctgac 82920 gttcaataag ttcttcaaat actcgatgcc gttgaatatc ataacgcgca ataccaagac 82980 ccgaaccaaa aaacataggt tcttttaaaa catcgacctg tttagtatta aaaactgtac 83040 tcattatttt gtcctgtaaa ctaaatttcc acagtcccag attcttctaa gaccatttgc 83100 ataacaattt tctacttcag ttattgtatc atcataattt ttaagcttgt ttttaagctt 83160 atgtttcata tagcttgagc ggtgaaatac ctctccttta tcgacatacc aataacatgg 83220 ctcagagata tgactaaatt ccatgacaga gtcataaaca tttgataatg tactgcacca 83280 tcttcgattg ccataagata gacaattaat tccttttaat aattttgagg ctcctcctac 83340 aacacaaatc cctaattttg aacacatcct taaaagttca tcacctgagc tatatctaga 83400 tttaccgata gaaataattt gaactaactc attattgtaa taaagtcctt tatacgtatg 83460 agctcctgag caaaatcctt gaagatgatt cttattaata aattcttttg cctcatcctt 83520 attaacaaaa cgtgctttgc attttcgggc tggtattctt tctgataatc ctaatttatg 83580 ctttataatg gatttccaga tctctctttt tgtatcatca atccattcat tttcgaagat 83640 gtgaagtaat tgaattcctt gtgcttcaca catctctgtc ttcatcaaat gataagtttc 83700 tttaatttta tctgtttcct ttgacccgct agaatgccaa taaattccat cgtattctat 83760 agccaatttt ttctcaggaa tgtaaatatc taattcatac ggaggaataa tttttctagt 83820 ttctacgcaa tcaaatccta gatctaaaat gaattgctct atagaacttt gagtataatg 83880 aacgtcaatt agtcctttgg atgaaagagc tctataagcc gtcatccgag aacaatttgc 83940 taattgttgt agttcttcta tagaaatttt gtaattgatt ttatctagta tatcatgatt 84000 aatatgaccg ttatttttaa tagattttcc tatagatgaa tataacgatg ccttatattc 84060 ttcagtccaa tttaatttag tcttcttaga tttttcgcga gattttctag aattcagaat 84120 atcaactaat ttaccgtttt ctataacttt tctcgcttct ttcacacttt ctaattgtga 84180 attatgcgtt acaccatatc gttcaattaa agtttttcta tttttatttc ttgaaatttt 84240 ttgatgagtt gttccatatt tttctaaaga atttttgcgt tgaagttcag acaaatattt 84300 tttatatttt tcttttccgc caaaatttgt atcacggctt tgaattctct tatccgcgaa 84360 aaatatccct gcgcaggatt tactacatgt tgctggaaat acacgtttct ttgctgtttt 84420 cagagaaatg aaatttccac aaactgcaca ttttagatcg ttaatgtcaa tgccttccat 84480 aatttggaac acattgagct taaaatctat tccatcagtt agaagagctt tatcttcttc 84540 tgttagtcta gatttaagtt tttcttctcc aaatggaaga aactttccgt ttttgtatat 84600 attatcaaac atagcgttat tcttagttaa ccacatcctt gtggtaatta tatcataatt 84660 tacaggatga acaatcatct gcttttggag tttctatttc ataatcatca gtaccggaac 84720 catcacgagt attatgataa tagaaatttt taatgccata ataccatccg tatagcatgt 84780 catcaatcat tattgacatt ggaacctttc cttttggaaa aatctgcggg tcataatatg 84840 tattcgctga agctgattga catacccatt tcagcataat agctacctgc gtaagataag 84900 gtttattacc tttcttagct aatttccatg tataatcata gaggtctatg ttatgctcaa 84960 tattgggcac gacttgatta aaggaaccct cttttgattc tttaacagag actggtccac 85020 gtggaggctc gataccgttt gtactgttag aaacttggga agatgactca catggcataa 85080 gtgctgataa tgtgctatta cggatgccaa agagcttaag gtcttcccgc agcgccgacc 85140 agtcacaaac gtattttgga gctgcgattt ggtcaatctt tttattgtac cagtcgatag 85200 gtaattcgcc tcgagaccaa cgagtgtctg aataatattc gcaaggtcct ttttctttgg 85260 cgagcttaat ggatgcttta atgagtccat actgtaatct ctcaaatagt tcatgtgtta 85320 aatcgttagc atcttcataa gaagcaaagt tacttgccag ccaagctgca tagttggtaa 85380 cacctacacc gaggtttcga cgctttttag ctttttctgc ttcaggaact ggatatcctt 85440 ggtaatccaa aagattatca agagcgcgaa cttgaacttc tgctaattca ttaattttat 85500 cttggtcttg ccaatcgaag ttatccaaca caaatgcgct aagggtacac aatccaattt 85560 cagcatcagg actattcaca tcatttgttg gaatagcaat ttcacagcac aagttactct 85620 gacgaatagg tgccttttca cgaataaacg gagtatagtt attcgtatta tcaatgaact 85680 gcacataaat ccttgctgtt cctgaacgtt cagtcatgag caattcaaat agttcacggg 85740 ctttaatacg ctttttgcga atattagggt ctttttctgc ggcttcatac aattcacgga 85800 aacggtcttg gtctttaaaa taagaataat aaagctcgcc acccatttcg tgtggactga 85860 acagagtaat gtagtcgttc tttccaaaac gttccatcat caaatcattc agttgaacgc 85920 cataatccat atgacggata cggttttctt ctacgccttt gttatttttc aaaacgagaa 85980 gattttcaac ttccaaatgc caaataggat aataagcagt agcagcgccg ccacgaattc 86040 caccctgtga gcatgattta acagcagtct gaaaatgttt ccaaaaagga ataacaccag 86100 tatggcgtac ttcacccatg ccaatcttag aaccttcagc acgaatcata ccaacgttaa 86160 taccgattcc ggctcgttta gaaatatact caacaattga agcagaagct ttattgatag 86220 acttcaatga atcacctgcc tcaataacaa cgcatgaact gaactgtcga gtcggagtac 86280 gacaaccagc cataatagga gttggcaatg aaatctgtcg agtagatact gcttcataaa 86340 aacgaataac atgttttaat ctatcaacag gttcatcttg atgcagtgcc attccaatag 86400 tcataaatgc aaactgcgga gtttcataaa tttgaccagt ggttttatct ttaactagat 86460 atttttcttt taattgcatc gccccggaat aagtaaattc catatcccgc tcgtgcttaa 86520 tttttgattc taaaaatgta atttcttctg ctgaatattt tgacaacaat tcagggtcat 86580 atttaccttc atttacacaa taagaaatat ggtcaataaa tgaacgtggt tcatactgcc 86640 cataaacatg cttacgaaga gcgaacatta aacagcgagc ggctacatat tggtaatcag 86700 gctcttcaac cgaaatagaa ttcgcagcag ccttaatgac aatagtctga atatcatcag 86760 ttgtcattcc atcacggaga taagatttaa tattttcata taattcataa ggatctactg 86820 atgttccttc agctgcccaa gataaaactt taataatttt ttgcgggtca aagctctgag 86880 aaacaccact acttttgata acattaatta attgcataag tcctcaactt gaaaatcgtc 86940 tttaaacaat cggttaacta tatgagctat tatatcacca tgacacggct ttggtttaca 87000 tgtgcatcct agcctcattc cacgtaaagg ctctaaatgt gctttagtta tttctccgga 87060 tttaattcga cgtataaaat cttttttgaa taattcaatg gcagcctccc ggctgccagc 87120 atctttaccg acgtaaaggc tctaaatgta ccacggtgaa tattaacatc aaagtcggat 87180 ttgtatttat tcactacccg gcatagacgg cccgcgcggt tgtaggtgtt catattgttc 87240 ttccgttaaa acagtaatat catagtaaca gtcagaagaa gttttaactg tggaaatttt 87300 attatcaaaa tactcacgag tcattttatg agtataatat tttttgccat aaatgataat 87360 aggctgattt ggtcctggaa cttctaactc acttggatta ggaagtgtaa aaagaactac 87420 accagaagta tctttaaatc gtaaaatcat atatcctcgc aattaaatta aaattatacc 87480 gccatctttc ctttaattgg cgggtgagat acatagttgt taagaacaaa attatgcggc 87540 tttgcgaatt gactcaacca aaatacctgc gattctgtgt cccattcatc aaattcatct 87600 ggaaatttta attgcaattc gcataaatcc ataggttcac gacgtaaaat ttctttacat 87660 tgttctacgt gattcatata gatatgagta ttaccgccag aaaatatcaa atctcctgga 87720 ataagattac acatcttagc tacaatatga actaacgcag cgtatgatgc aatattaaat 87780 ggaagcatta tgttcagata aggtcgttaa tcttaccccg gaattatatc cagctgcatg 87840 tcaccatgca gatcagacta tatctccaac ttgttaaagc aagttgtcta tcgtttcgag 87900 tcacttgacc ctactcccca aagggatagt cgttaggcat ttatgtagaa ccaattccat 87960 ttatcagatt ttacacgata agtaactaat ccagacgaaa ttttaaaatg tctagctgca 88020 tctgctgcac aatcaaaaat aaccccatca catgaaatct ttttaatatt actaggcttt 88080 ttacctttca tcttttctga tattttagat ttagttatgt ctgaatgctt atgattaaag 88140 aatgaattat tttcacctga acgatttctg catttactac aagtataagc agaagtttgt 88200 atgcgaacac cgcacttaca aaacttatgg gtttctggat tccaacgccc gtttttactt 88260 ccgggtttac tgtaaagagc tttccgacca tcaggtccaa gtttaagcat cttagcttta 88320 acagtttcag aacgtttctt aataatttct tcttttaatg gatgcgtaga acatgtatca 88380 ccaaacgttg cgtcagcaat attgtatcca ttaattttag aattaagctc tttaatccaa 88440 aaattttctc gttcaataat caaatctttc tcatatggaa tttcttccaa aatagaacat 88500 tcaaacacat taccatgttt gttaaaagac ctctgaagtt ttatagaaga atggcatcct 88560 ttttctaaat ctttaaaatg cctcttccat ctcttttcaa aatctttagc acttcctaca 88620 tatactttat tgtttaaagt atttttaatc tgataaattc cgcttttcat aaatacctct 88680 ttgaatatag aagtatttat taaagggcag tcctacaatt tagcacggga ttgtctacta 88740 gagagtttcc ccgtttagat agattacaag tataagtcac cttatactca ggcctcaatt 88800 aacccaagaa aacatctacc gaacgttgat accactgcaa atccaaatag ccattacgca 88860 cattaaattg ataaaacata tgacaaggcg gtaatgccat ctgcttgagt tcagctggat 88920 tccatgcaga aacaatttga cgcctatcat ttggcagttt tttaatacga tcaataactt 88980 ctataatttg gtctacacca ccaaaatcac gccactgttt tccataaatt ggaccaagtt 89040 caccgctatg gtatcctaaa tcttttgctt gattttcgta attttcatcc cagactgttt 89100 tgccttggat taatgaatca tgctgaatta atcgtaaatc attgacattt gtgcttcctg 89160 ataaaaacca tattaactca gcaatgcaag ctttccaggc gagcttctta gttgttaccg 89220 caggaaaacc tttagttaaa tcccagcgta atttagtacc gaacaaagca attgttcctg 89280 tgcctgtacg atcatcggtt tcataaccat tttcaaaaat gcctttaatt aaatcttggt 89340 attgtttcat ttatatactg attccgtaag ggttgttact tcatctattt tataccaatg 89400 cgtttcaacc atttcacgct tgcttatatc atcaagaaaa cttgcatcta attgaacagt 89460 tgaattaaca cgatgccttt taacaatacg agaaacaact acttcatctg cataaggtaa 89520 tgcagcatat aacagagcgg gtccgccaat tacacttact ttagaattct ggtcaagcat 89580 agcctcgaat ggtgcattag ggcttgacac ttgaatttca ccgccagaaa tgtaatctat 89640 atattgctcc caagtaatat agaaatgtgc taaatcgcca tctttagtta caggataatc 89700 acgctcaagg tcacacacta caatatgtct acgaccagga agtaatgtag gcaatgactg 89760 gaacgtttta gcacccataa tcataattgt gccttcagtg cgaactttaa aattctggag 89820 gtccttttta actcgccccc atggtaaacc atcacctaaa ccgaatgcta attcattaaa 89880 gccttcgacg gttttagttg gagaataagc gaataccaat ttaatcatta cgcaaagccc 89940 ctttcaagaa accattcagt ggctttatta gcatcaaaga ataattcttc atatgtcttt 90000 tctttgtttt caaaaactgt cacacaaaca cgttgacatt ctccacagta ttcttctgac 90060 atacgcaaag catcagaaaa catttcatta aattcactta aatcaggatt atgcaatgcg 90120 ttaaaaattg cataatcgaa ttcatcattc ataaattcaa atacaaaaat catattattt 90180 tccttaaaca gactttttca caattttcca atcagcttta aactgttcaa cgtcagaatg 90240 gtaaatccag aatcctgcgc tttctccgtc ttcataaaga ggacatccat cgcattcatc 90300 ttcccacccc atatcacgta aaagatgttc agctttttca acaagttcag aatctttacc 90360 gatgatatta aaataccatt tacctctaac ttctgaatct ttgatgctct ggcgttgtaa 90420 tctcatttta ttctcctcag tagttgatag ggtaatagta tcacactact accctgttgt 90480 aaacaattat ttttgaattt tatcgagcca cttaccaagc ttaatcattt ctttagtagc 90540 cttttccata cttctgaact taaccaatag aggatatgta tcgacaccca taactaaact 90600 ggttacaaga ctgtgttcac ccacaagcca taacgaatac gtttgaatat cgagtccgta 90660 atttctgtct ttatggaccc gtacacccat cacttcaaat ttctcactag ctttttctac 90720 cgcatccagg aaatcatctt tagtcatatt aggccttaaa agtttttcgc aaaagttcaa 90780 tgatttcgtc tacattattt tcgtcaacaa tgcagtgaat ttttgttacg ccagaaacct 90840 tgtctttgac ttcatcttct tcagaagtcg gttctttata ttcgcggaaa caataaaact 90900 cttcttcact aagttcaaaa taatcatcac ccataccatc atcattatag atttcaccat 90960 tggcgcaaat gatttcggtt acataatcaa atccatctaa acttgatatt gatttaactt 91020 caaaccaacc gccattttct tgaatgatgc cgaccatact agcatttgat gaactaatat 91080 caatgaaaga tttaatacgg tgtggattta actcatattt tttgccgatt tccatttttg 91140 attttcctca ttttaatagg ggcttgatag ccccttgata attattgttc aatcaatccc 91200 atgtaaaatt ctgcgtcttc agaatccatg ccatcacaat attcattagc cataaagagg 91260 gtgaggtctt caagaggacc tttaataacg atttgaatac tccaaaactt agaatcttgc 91320 acgcttgtga tactaagttc aggataacga ttacgaataa tttcttcaat atattcaaaa 91380 tcaacgatgt caatatcaac tttagccata ttattttcct ctttaatcat cagcagtatt 91440 gccgatagtt gtatcgtacc acggaagaac ggggatgtaa accgttttgt gaaaaaattt 91500 ttgaaataaa aaaggggacc tctagggtcc ccaattaatt agtaatataa tctattaaag 91560 gtcattcaaa aggtcatcca ggtccgtgtc atcagcacta gatgaactgc cagagcttga 91620 gctcataaaa tcatcttcag tttttgtttt gaagtcatca acattgaatg catccaaatc 91680 atcagcaact ttatcagctt tcttagcggc agttgctgcg gcaccaccca tagcagcagt 91740 tcccataact tgactgaact tagtgctcag ttcttcaaac gatttgaatt tatctttaga 91800 agtcatttca gaaaggtcaa ccatttgttc gaacagttct ttctggaaag attcatcatc 91860 aatgtttgga atcgcagatt gattcaggaa tttagattcg tcgtagttac taaaaccaga 91920 aacttgttta actttcagta caaagttagc accttcccac gggcaagtta catcaaccgg 91980 agtttcaccc atttcaacat caactgcaat cattgcattg attttatccc agattttctt 92040 accgaaacgg tatttaaata ctttaccttc attttctgga gcagctgggt cttttactac 92100 aagaatgtta gcccagtaag aagttttacg tttaacaaga ccgtactctt tattgtcagt 92160 gttgtacaaa tcatttttac tgatgtactg acatactgga caagaatcgt aatcaccgtg 92220 ggtagatgaa catgtttcaa tataccattt accatttttc ttgaaaccgt gatttacaag 92280 aattgcgaat ggtgcttgtt catcattttt agacggaaga aaacgaatta ctgcttgacc 92340 gttacccgca ttatcgagtt tcagtttcca ctcgccttta tcttcagaag aaaaaccttt 92400 attgccattc agtttagcca tttgtgcagc aagttcagca gtagatttac gtttaaacat 92460 tttatttcct tttaatttaa tttaatttaa tttaattaac agttggtgct atgacgatgt 92520 atgacctcat agctggtcag tgagataatt ataatctatt tataataagc aattaatact 92580 tacaagattt cacagtttca ataaaaactt ttttagcttc ctgtgaatca atatttaaaa 92640 tttttctata agcctttaac tttatagaat aattattcca gactaaatta tcagtctgtt 92700 catcgtgttt atcaattata tttaaaaatg aatcaagcaa gataaacgtc tcaaacgaaa 92760 ttatgttcga ttgcagaagt ttaaaaatat aacttgattg aacttttgga ttatattcaa 92820 aaatttcttt aaaagcagaa acttcaactt ttttactgaa atagtaaatg ttgcgaatat 92880 cttcttcaaa cttaaattta atttgcttta agcgtccgat atattcacga taaaacacaa 92940 gtgcatcagc gtcagagatg tcaccaatcc aagcatcttg gttagcaacc aaattactta 93000 taaagattaa agcaagttcc tttaatttat atttttctga taacttctga aaaaaatact 93060 tatcccttcg cttttgataa gcggcatcag acacccgcat gcaccaatta tacttaatta 93120 catcatactt tccattcata tgctgtttta tcattaagta taatttataa actgatttac 93180 catcaatgta tctttcacca ccagcaggca tgcggagttt aatcatagta gaaaatctaa 93240 tgtattagtt ttttcacaac gaacaacaga aggacgtaaa agattttcgt caatagcttc 93300 tgactgaatt ttttcaatta tacccgaagg aataaattta gcaaattgag tttcaggaat 93360 agaattttct tccaagaatg ctgttgtagc ttcaagataa ctcattccaa actcttctac 93420 cattttttca ataataaatc cattttcttg acgatcaaga agctttgcta tttcatcctt 93480 ttctttcttg attgaaagtt ctttttctga aagaccggtc tcatcgaccg gacgaatgtc 93540 atttagagaa aactgtgtca taaagttcaa ctacctcttc agtttcagct tcaaacacat 93600 cacgattatc tttatgatac aaagctaata gacgattaaa catcttacca tcaacgccaa 93660 gttcatcttt ggcacgaatt cgaatatctt taatcagttc attataaccg gaaattttca 93720 gtttatgatc agatgcttct ttaataaatt tagccaagtc ttcgccatgg atagcttcat 93780 caaattcaac catttctttt ttagccatta ttcacctcaa aattcattaa tgctattagt 93840 taatttagaa agacccgctt ttacaaaata tgaataaatt tttccacgcg gtggtaattt 93900 atatgaatta tagtaattca caatgtttga agcaatatta tcaggaatat aatcaaaatc 93960 aattagaact aaattttctt tataccgatt atattcagat tctgtgagaa gcaccttagc 94020 ttgctcacgg tcattagcaa tagcttcaac gattgaagtt ttcattgaag gagttcgttc 94080 accttcaact ttggtaaacc aaaagtcaga tcgtacttta actgaagcaa cgttatcctt 94140 tttatcgcct ttaaggattt tagtcataca gtcaatttca gcagaaccgc ttttaatttt 94200 aacccatttc ttgtgcatcg gtgaccattg cttaacattt ggatatttgt gaagttgagt 94260 aaagtcacca tcagatgaaa tgatcaaaat cttatgtcct tctaaagaga actttttaac 94320 aagaacagca atatggtcat ctgcttcata cttatcaata tccataacaa tgtatggcat 94380 ataagctttc aattcatcta taactttatg actggattca aaataacctt cccagtccca 94440 agtagattct tctcgtgctt ttccacggtt tttcttataa taataagcaa aatcacgacg 94500 ccaatatcca gatttcgcgt tatcaataca cagtacaatt ttagtgtatc caagagtttt 94560 tgcttttttg acattaaact taattgagtt caatatcaaa tgacgaacca tcgataaatt 94620 aattttttct ttatctggga agtttactaa agcggttgaa agcgcaatct gactaaagtc 94680 aattaagcaa attccttctt tgtaatcttc atccagcatc atttctaaat ccatatgaac 94740 ctcgttcaat tagtgagatt tctattatat actatccaaa tcttaaagta aacaagtata 94800 aatacttatt attgaaaaca caataggagc ccgggagaat ggccgagatt aaaagaaagt 94860 tcagagcaga agatggtctg gacgcaggtg gcgataaaat aatcaacgta gctttagctg 94920 atcgtaccgt aggaactgac ggtgttaacg ttgattactt aattcaagaa aacacagttc 94980 aacaatatga tccaactcgt ggatatttaa aagattttgt aatcatttat gataaccgct 95040 tttgggctgc tataaatgat attccaaaac cagcaggagc ttttaatagc gtacgttgga 95100 gagcattacg tactgatgct aattggacaa ctgtttcatc aggaccttat caattaaagt 95160 caggcgaatc aatttcagtt gatactgcag ctggtaatga cattacattt actttaccat 95220 cttctccaat tgatggagat actatcgttc ttcaagatat tggtggaaaa cctggtgtta 95280 accaagtttt aattgtagct ccagtgcaaa gtattgtaaa ctttagaggt gaacaggtac 95340 gttcagtact aatgactcat ccaaagtcac agctagtttt aatttttagt aatcgtctgt 95400 ggcaaatgta tgtcgctgat tatagtagag aagctgtagt tgtaacgcct gcgagtctct 95460 atcaggcgca atcaaacgat tttatcgtac gtagatttac ttctgctgca ccaattaatg 95520 ttaaacttcc aagatttgct aatcatggcg atattattaa tttcgtcgat ttagataaac 95580 taaatccgct ttatcataca attgttacta catacgatga aacgacttca atacaagaag 95640 ttggaactca ttccattgaa ggccgtacaa cgattgacgg tttcttgatg tttgatgata 95700 atgagaaatt gtggagattg tttgacgggg atagtaaagc gcgtttacgc attataacga 95760 ctaattctaa tattcgtcca aatgaagaag ttatggtatt tggtgcgaat aacggaacag 95820 ctcagacaat tgaacttcag cttccgactg atatttctgt tggtgatact gttaaaattt 95880 ccatgaatta catgagaaaa ggccaaacag ttaaaatcaa agctgccggt gaagataaaa 95940 ttgcttcttc agttcaattg ctgcaattcc caaaacgctc agaatatcca cctgaagctg 96000 aatgggtgac tgttcaagaa ttagttttta acggcgaaac taattatgtt ccagttttac 96060 agcttgctta tatagaagat tctgatggaa aatattgggt tgtacaacaa aacgttccaa 96120 cagttgaaag agtagactct ttaaatgatt ctactagagc aagattaggc gtaattgctt 96180 tagctacaca agcccaagct aacgtcgatt tagaaaattc tccacaaaaa gaattagcaa 96240 ttactccaga aacattagct aaccgtactg ctacagaaac tcgtagaggt atcgcaagaa 96300 tagcaactac tgctcaagta aatcagaaca ctacattctc ttttgctgat gaccttatca 96360 tcactcctaa aaagctgaat gaaagaactg ctacagaaac tcgcagaggt gttgctgaaa 96420 ttgctacgca gcaggaaact aatacaggta ctgatgatac tacaatcatc actcctaaaa 96480 agcttcaagc tcgtcaaggt tctgaaacat tatcgggtat tgtaactttt gtatctactg 96540 caggagctac tccagcctct agtcgtgaat taaatggtac aaatgtttat aataaaaata 96600 ctaataattt agttgtttcg cctaaagcac tggatcagta taaagctact ccaacgcaac 96660 aaggtgcagt aattttagca gttgaaagtg aagtaattgc tggacaaagc caagaaggat 96720 gggcaaatgc ggttgtaacg ccagaaacgt tacataaaaa gacatcaact gatgcaagaa 96780 ttggtttaat tgaaattgct acgcaaagtg aagttaatac aggaactgat tatactcgtg 96840 cagtcactcc taaaacttta aatgaccgta gagcaactga aagtttaagt ggtatagctg 96900 aaattgctac gcaagttgaa ttcgacgcag gcgtcgacga tactcgtatc tctacaccat 96960 taaaaattaa aactagattt aatagtactg atcgtacttc tgttgttgct ctatctggat 97020 tagttgaatc aggaactctc tgggaccatt atacccttaa tattcttgaa gcaaatgaga 97080 cacaacgtgg tacacttcgt gtagctacac aagttgaagc tgctgcagga aaattagata 97140 atgttttaat aactcctaaa aagcttttag gtactaaatc taccgaatcg caagaaggtg 97200 ttattaaagt tgcaactcag tctgaaaccg tgactggaac gtcagcaaat actgctgtat 97260 ctccaaaaaa tttaaaatgg attgtgcaga gtgaacctac ttgggcagcc actccagcca 97320 taagaggatt tgttaaaact tcatccggtt caattacatt cgttggtaat gatacagctg 97380 gttctacgca ggacttagag ctatacgaga aaaatagtta tgcagtatca ccatatgaat 97440 taaatcgcgt attagcaaat tatttgccat taaaagcaaa agctgtagat agtaatttat 97500 tagatggtct agattcgctc cagttcattc gtagggacat tgcacaaaca gttaatggtt 97560 cactaacctt aacccaacaa acgaatctga gtgcccctct tgtatcatct agtactgcta 97620 cattcggtgg atcagtttca gcaaatagta cactaaccat ttctaatact gatggaacag 97680 caactcgtct gatttttgag aaaggacctc aaactggaac gaacccggct caaacgatga 97740 cagtcagcgt gtgggggaat caatttagtg gggaatcaaa cacaacacgt tctaccgtat 97800 ttgaagttag tgatgaaaca tcttatcact tttattctca acgcgataaa gatggtaata 97860 tagcatttag cattaatggt actgtaatgc caataaatgt gaatgcttta ggttctttga 97920 atgcgaatgg cgttgcaaca ttcggtagtt cagttactgc taatggcgaa tttatcagta 97980 aatcgtcgaa tgcttttaga gcaataaatg gaaattacgg attctttatt cgtaacgctg 98040 gtaatgacac ctattttatg ctcactgcag ccggtgacca aactggtgga tttaatgcat 98100 tacgtccatt atcaattaat aatcaatctg gtcaagtaac gattggtgaa agcttaatca 98160 ttgccaaagg tgctactata aattcaggcg gtttgactgt taactcgaga attcgttctc 98220 agggtactaa aacatctgat ttatacaccc gtgcaccaac atctgaaact gtaggattct 98280 ggtcaattga tattaacgat tcagccactt ataaccagtt cccgggttat tttaaaatgg 98340 ttgaaaaaac taatgaagtg actggacttc catacttaga acgtggtgaa gaggttaaat 98400 ctcctggtac attgactcag tttggtaata cacttgattc gctttaccaa gattggatta 98460 cttatccaac gacgccagaa gcgcgtacca ctcgctggac acgtacatgg cagaaaacca 98520 aaaactcttg gtcaagtttt gttcaggtat ttgatggagg taaccctcca caaccatctg 98580 atatcggtgc tttaccatct gataatgcta taatgggtaa tcttactatt cgtgatttct 98640 tacgaattgg taatgttcgc attattcctg acccagtgaa taaaacggtt aaatttgaat 98700 gggttgaata agaggtatta tggaaaaatt tatggcagag tttggacaag gatatgtcca 98760 aacgccattt ttatcggaaa gcaattcagt aagatataaa ataagcatag cgggttcttg 98820 cccgctttct acagcaggac catacgttaa atttcaggat aatcctgtcg gaagtcaaac 98880 atttagcgca ggacttcatt taagagtttt tgacccttcc accggagcat tagttgatag 98940 taagtcatat gctttttcga cttcaaatga tactacatca gctgcttttg ttagtttcat 99000 gaattctatt tcaagcaata gacttgttgc tatattaact agcggaaagg ttaattttcc 99060 tcctgaagta gtatcttggt taaggggagc aggaacgtct gcttttccat ctgattctat 99120 attgtcaaga tttgacgtat catatgctgc cttttatact tcttctaaaa gagctattgc 99180 attagaacat gttaaactga gtaatagaaa aagcacagat gattatcaaa ctattttgga 99240 tgttgtattt gacagtttag aagatgtagg agctaccggg tttccaagaa gaacatatga 99300 aagcgttgag cagtttatgt cagcggttgg tggaactaat aacgaaattg cgcgtttacc 99360 aacttcatcc gcgataagta aattatctga ttataattta attcctggcg atgttcttta 99420 tcttaaagca cagttatatg ctgatgccga tttacttgcg cttggaacta caaatatatc 99480 tatccgtttt tatgatgaat cgaatggata tatttcttca acacatgctg agtttactgg 99540 acaagctgag tcatgggaat taaaggaaga ctatgtagtt gttcctgaaa atgcagtagg 99600 atttacgata tatgcacaaa gaactgctca agctggtcaa ggcggcatga gaaatttaag 99660 cttttctgaa gtatcaagaa atggcggaat ttcaaaacct gccgaatttg gcgtcaatgg 99720 tattcgagtt aattatgtct gtgaatctgc ttcacctccg gatataatgg tacttcctac 99780 acaagcatcg tctaaaactg gtaaagtgtt tggacaagaa tttagagaag tttaaattga 99840 gggagccttc gggttccctt tttctttata aatactatta aaataaaggg gcatacaatg 99900 gctgatttaa aagtaggttc aacaactgga ggctctgtca tttggcatca aggaaatttt 99960 ccattgaatc cagccggtga cgatgtactc tataaatcat ttaaaatata ttcagaatat 100020 aataaaccac aggcaactga taacgatttc gtttctaaag ctaatggtgg tacgtattta 100080 aataaagtaa tttttaataa aggaatgact gttcctggtg cagggtcagg tgacaatggt 100140 atttttgctg gtcctggtga taatgccacg tatgatacta caaatatgga tattgtttct 100200 tggtatggta ttggttttaa atcatcacaa ggaacagcag gtagaactgt agtaattaac 100260 acacgaaatg gagatattag ctcaaagggc gtaattgaag catcacaaat acgagcaact 100320 tcgttatcac cagtaaataa ttatgacctt acgcggaaag attatgttga tggagcaata 100380 aatattgtta cagcaaacgc aaactctagg gtattacgct ctggagacac tatgacagga 100440 aatttaactg cgccaaacct tttttcacag aatcctgcat ctcaaccctc acatgttcca 100500 cgatttgatc aaattgttat taaggattct gttcaagatt tcggctatta ttaagaggac 100560 ttatggctac tttaaaacaa atacaattta aaagaagcaa aactgcagga gcacgtcctg 100620 ccgcttcagt attagccgaa ggtgaattgg ctataaactt aaaagaccgc gtacttttta 100680 ctaaagacga ccaaggaaat atcattgatc ttggttttgc taagggcggt agcattgacg 100740 ggaatgttat tcatacaggc aattataacc aaactggcga ttatacttta aatggcgtct 100800 tcactcagac tggtaatttt aatttaactg gtattgctcg agtaactcgt gatattattg 100860 ctgctgggca gattatgact gaaggcggag aacttattac aaaaagttca ggaacggcac 100920 acgttcgttt tcatgattcc gccgaccgtg aacgcggtat tattttttct cctgctaatg 100980 acggtttaac tacacaagta gttaacatca gagttcaaga ttacaaagct ggttcagaaa 101040 gcactttcgc ttttaatgga aatggtttgt tttcttcacc agaagttttt gggtggaaat 101100 ctatttcgtc tccacaaatt ctgaccgaca aagttattac aaatgggaag aagacaggcg 101160 attatgatat ctattcatta tcaaataaca ctccaatggc agaaggcgaa acggctatta 101220 accacctccg tgttatgcga aatgctgtag gagcaggtat tttccacgaa gttaatgtta 101280 atgacggaat aacctggtat tccggagatg gcttagacac ttatctttgg tcgtttaact 101340 gggctggtgg attgaaagcc ggacattcta tttctgtagg tcttccaggc ggtcgcaaag 101400 gatattctga attaggaacg gcctcaattg ctcttggtga taatgatacc ggatttaagt 101460 ggcatcagga tggatatttc catacagtaa acaatggaac aagaactttc atctacggcc 101520 ctgcggaaac acaaagcctt agaaaaatgg ttatgggtta ttctccggac gggattctta 101580 tgacaacgcc accgacagaa aactatgctc ttgctactgt agtgacatat cacgataata 101640 acgcggttgg agatggtcag actcttttag gatattatca aggcggtaac tatcatcatt 101700 atttccgcgg caagggcact acaaacatta atactcacgg cggtttgtta gttactccag 101760 gcaatattga cgttattggt ggttctgtta atattgatgg tcgtaataat tcttctacgc 101820 tgatgtttag aggtaacaca acaggtagta gttctgtgga taacatgaca atttctgtgt 101880 ggggtaatac atttattaat cctagcgaag gtaatcgcaa aaatgtcatg gaaatttctg 101940 atgcaactag ctggatgagt tatattcaac gaacaactgc aggtaaagtc gaatcggtta 102000 taaatggcac ccagattgtt aatgaaaact tgacagtagt aaaaaatgct acatttgacg 102060 gtacaatcag cgcagccggt gaaatcgcga caaatgctgt aaatggtctt cgcatttgga 102120 acgcagatta tggagccatt tttagacgtt cagaaggcag tcttcatatt attccaactg 102180 cttacggtga aggtaaacac ggcgatatcg gtccacttcg cccgtttagt atggctttag 102240 atactggtaa agttactatt ccagatttac aatcaagtta caatacgttc gcagcaaatg 102300 gctatattaa atttgctggt catggagctg gggctggagg ttatgccgtt caatatgctc 102360 aagcggctcc tattttccag gaaattgatg atgatgctgt aagcaaatat tatcctattg 102420 ttaaacagaa attcttaaac ggtaaagcag tttggtcttt aggtactgaa attaattctg 102480 gtacattcgt tattcatcat ctgaaagaag atggttcaca aggccatacg tctcgtttta 102540 atcaagacgg tactgttaac ttcccaggta atgttctggt cgacggtgat attaacatga 102600 aaggcgtgat gacttttgac gccggacgtt taggatcacg agattatttt aaatttaacc 102660 attggggcga tagcaataac gctcgtgata acatcatcca gttagaagat agtcaaggcg 102720 ctcatttttc cactgaacgt actttagcga caggtgcaat taaaactcgt ttctttggcg 102780 aaacatttac tgatggtaca ttatacctaa atcagatgaa taatagctct gaacgattcc 102840 atatcaataa ttggggaaat tcagaagttg gtcgcgcggc agtgatggaa gtcggtgatt 102900 ccaaaggtta tcacttctat acagaacgca ggacagataa cagtttgacg tttgatgttg 102960 ctggcgcttt taccgtgcat ggatctagcg ggatcactat caaaaactct gctggcgctc 103020 gccacatctg gtttaaagat gatagcgaat cggaaaaggc tgttatctgg gctacagatg 103080 agggtatttt acatatacga aataattatg tgggttcatt tagtcatcac ttccagggtg 103140 caatgattaa agtgggagag cgtgttcctt atgccggaga tcaagggctt attcgcggtg 103200 aagtttctgg tggtgcatat gttgcatgga gagaacgccc tgctggtttg ttgcttgact 103260 gtcaacaaag cgttaatagt gctcatgcca tttggaaagc ggttgattgg gggcgtaact 103320 acatcgctgc tctggacgtt cattgtcccg gtgatagtaa taatactgcg gcagcggttc 103380 tccatgttca gtctgctgat tatcaattcc atgcaagtgg agaatttcat gccactggta 103440 acggaaactt taacgatgtt tatattcgat cagaccgtcg cctcaaagaa aacatcgaag 103500 attatatagg aaatgcaact gatttaatcg gtaaactgaa agttaaaacc tacgataaag 103560 ttaaatcatt atccgaccgt gaaattatcg gtcatgagat cggcattatc gcacaggatt 103620 tacaagaaat attaccagaa gcgattaata tttcgaaaat tggcaatctt gataaaccag 103680 acgaagttct gacaatttct aactccgctg tgaatgctct tttaattaag gccattcagg 103740 aaatgagtga agaaattaaa gaattaaaaa cgcctttctt cactaaaatt gctcgcaaaa 103800 ttggtaaata ctttaaattc taataacaag ggcattgccc ctttggagat aaattatggc 103860 agtagttggt gttcctggtt ggattggtag ttcatccgta aatgaaacag gacaacgatg 103920 gatgagtcaa gcggctggtc aattaagatt aggtgttcct tgctggatga gtcaatttgc 103980 aggtcgctca agagaaatta ttcatacact tggagcagac cataacttta atggtcaatg 104040 gttccgagat agatgttttg aggcaggtag tgcacctata gtgtttaata tcacaggaaa 104100 tttggtatca tattctagag atgttccttt attcttcatg tatggagata caccaaatga 104160 atatgttcag ttgaatatta gcggtggagc tcatatgtgg ggcagaggtg gacaaggtgg 104220 atggactcat tctggtggag atggtaatgg tcaacagggt ggacattgta ttcaaaatga 104280 cattggtggt cgattaagaa ttaataatgg tggagtaatt tgtggcggtg gtggcggtgg 104340 tggcggtatc gcttatcgtc ctcactctgg cgcaaggtgg caagatattg gtggcggtgg 104400 aggaagacca tttggcccag gaggaggcgg aggttattcc ggtggcgcag cttcttatga 104460 tggcccagga ggtggttata attatggtat tgctcactct ggccagggtg gtgatgctgg 104520 cgcaaatgga caaaatgcct ggcatgatgg cggtaaagtt ctaaaagttg gagctggtgg 104580 cgctgccgga tatgctgtta taggatcagc tccaacatgg caaaatgttg gagtaatata 104640 tggtccaagg gtataatttg aataaatatc cttaaaagga gggtctatgg cagcacctag 104700 aatatcattt tcgccctctg atattctgtt gggtgttcta gatcgcttgt tcaaagataa 104760 cgctaccggg aaggttcttg cttcccgagt agctgtcgta attcttttat ttatgatggc 104820 gattgtttgg tataggggag atagtttctt tgagtactat aagcaatcaa agtatgaaac 104880 atacagtgaa attattgaaa aggaaagaaa tgcacgcttt gaatctgtcg ccctggaaca 104940 actccagata gttcacatat catctgaggc agactttagt gcggtgtatt ctttccgccc 105000 taaaaactta aactattttg ttgatattat agcatatgaa ggaaaattac cttcaacaat 105060 aagcgaaaaa tcacttggag gatatcctgt tgataaaact atggatgaat atgcagttca 105120 tttaaatgga cgtcattatt attccgactc aaaatttgct tttttaccaa ctaaaaagcc 105180 tactcccgaa ataaactaca tgtacagttg tccatatttt aatttggata atatctatgc 105240 tggaacgata accatgtact ggtatagaaa tgatcatata agtaatgacc gccttgaatc 105300 aatatgtgct caggcggcca gaatattagg aagggctaaa taattatttg ttcgtataca 105360 tctctagata tcgatataca ccctcaaaac cctcgttgaa ttcgtcgatg agggttttct 105420 tatcttcttg agttaattca gaaacaattt tacggaatga attctgattt aactttctac 105480 cttcatgtgt tactccaatc tcattcagaa atgcaataaa attagcacga ttctcaacaa 105540 tatcttctct ggaaaattta atcaaaatag acgcaacagt aataatttca cgaactgcat 105600 caatattttt attcattaac tataccactc aattagttga ctttattata atatcatcag 105660 acacttgatt tgtaaactgg tctgtgttat tttcttcaaa aattttttct acgaattcct 105720 taaacgactc gcgttcctga gctacattat gctcgattac catttcaaga ttatgactca 105780 ttcgaaataa tcttcaattt cgtaatcatg gacataaatc attatagttt ttaatacatc 105840 atcgatactt tttcctggag ctggaattac gtagaaatat cctgcttttg agaggtcttt 105900 ataagttcca attaagaaat cgttattctc aagatgcagt tcttcaacta attcattaac 105960 aattgaatgg tataaatttg gtagaaactt atatagcttt tctagaatat caattttgat 106020 tgtatattga accacagact gagaatcaat aatcatagac cttcccctta tgtttctgtt 106080 tgcgattaga ttctttaaac gctttcttct tatccttatg aacagaagct ttattaaaat 106140 tatgttttgc gactaaattg ttcatagtgc tgaattacct ctctcaaaca tttgcatgtg 106200 aatgaaaact ttttagctac accacattca aatatatgtt ctcttaaatc acgtgtgtca 106260 gtatatccca tctcaacaat aaaatgccgt attagatttt tatctttatc attgagagaa 106320 ttaaaataat cggattttga attaatttcc ctggccaaat tgaatcacct tcagttgacg 106380 ttttagttct tttatcattt cttcgttcat cgcaatataa agatcgcgta aagcaggttt 106440 tatcattcca tttattgggg aactaaatgg acatacataa tcttttccta cgagcttttt 106500 agttaattcc atatcacaaa actgaaatgc aggttcatta gcataaattc cccaattagt 106560 tgacatcatt ttattggcat attccaatgc ctggatttga ttcataattc catcaatttg 106620 aaatttttta atattcatta gtaaaggtcc tcagagtaaa gttctttttc actaccgccg 106680 cgttcaatac gtacctgtcc agcgtaagtt gcaataatca ttgcttcttc acgtgtccaa 106740 taattactat attggtcaat aaacccttgg tcatcatcac aaacttgctg agtaactaat 106800 tggggtttaa ctacatctaa aacttcggcc atatctttag aataatgacg agcacccgga 106860 ataataagag ttcgtccatc ttttaattta aaacggttgg ctgcgcaaac aattcgtcgt 106920 tgatactttt gattttcatc ccaatatgca gtctgccaac agatttcagg aacttctttt 106980 aaaatatctt cttctgtgca tttataacca tgcgctttaa atttttcaac aagactttct 107040 ggagtttcac gagataaagg aacattcagc atttttaaac gattaataaa tgggttcatt 107100 taaaccatcc tttaatacgt tgccacaaag ttttctgttg agctttgtta acgccaattg 107160 agcgaataac cggttgagat tcctggaatt ctttataatc agcaaggtaa atttcgtaag 107220 ctgcatctgt aaaggaactt atcgctgcca tgaaattatt gcgaatacct actggagcat 107280 ctttactttc acgaataatc atgtatttac cagtcttaat ctttacaata gttccaagat 107340 aagctccatg gtaccaaata tcccaaccct cttgagtagg ttctgcacaa cgacgaagtt 107400 cattgataat ttctaacttg ttcattattt attcctcaca gttcagatgc tacggtaatt 107460 actgcttcaa tgttttctgc tgagcgttta atgtcaagat acacattacc gtttttagcg 107520 attttacatg acattccgat atcaataaat ttctgaatat gatgttccat cattttgtat 107580 ccaaaaattc gcatatttcc attgttgtta atttcaaaat tacgaattcc gtgagtgcgt 107640 ttttctaaaa tagcgagata gttactacga taagtttcaa cctttttaag aacaaatcca 107700 ttttcatcta aaagttttaa catgaagtct ttatcttctt ccatatcaga agtaatctcg 107760 cgagctttac gagttgctcg ttttttcaac agttcaggag cgttttcctg cgcgtataaa 107820 gttgctgcat ttgaaataat atcctgagct tcaccagtaa tgattaatcc atcaccagat 107880 ttctctacca ggcctttttt aatcaatacc ccaatattac tattaactac tgcattacct 107940 aaatctggat gcacctcacg aacttctgca gctgtaatga aatctttctt agcaatggta 108000 attaaaatcg cagcagtttt ttcattcaga acatcgttag aagctttgat gatgtaagtt 108060 actttagaca ttttctaatc tccgtaattc tgtatcagta gttgatagtt gtatagtacc 108120 acagtatgct ttggttgtaa accgttttgt gaaaaaattt taaaataaaa aagggagagc 108180 cgaggctctc cctaaaatta ctgcatgact gtgataacta tcatgataac acgttgaatt 108240 ccgaacgcaa gaagacctcc tgctacagct ggaacaacac ctaaacccgc cagtaaaatg 108300 ccaccggata ctaatgcagc gcttgtgata ccaatgaatg gactcatttg atttcctcta 108360 aatctttggt gtattctgta actacatcag tagttttcca atattcgttt tcttctttct 108420 tagctttagc ttcttcagca agtttctttg cttcatcaga agtcatatga aaaatattca 108480 ttccaactag tttatcaaca taagaagaat acatatcaat tttagaaagt tcttcggtca 108540 gttctttgcg agttttacct tgcacaacaa tttcacctga aattactttc ttaatgaaat 108600 gtgccttggc aaaggctaaa cgaaatgctg attcagtttc tttgattttg ttatcaattc 108660 gtttttgaac ataagtttta cgaacttcaa cgaagtcttt gattaaatca actacgttgt 108720 cgtaaacttg cagttttcct ttctcattaa tgacggtaat attctgagaa cgacgttcaa 108780 tcaatccgaa gtctttcaca atttttgcat gacgttcttc ttcattatcg ctcaaagagt 108840 attctttgcg gaatttaact ttgaatccaa acccatgctc accacaagca tcatcccatg 108900 taatgaagcc tttatcttca agtgggtcta agattttact cacataagtt tcacgatcat 108960 acttatacgg aatctcagtg atatgcattt gagttcgtga agtaaactta tatgttccac 109020 gaatttcata ttgcccatca atttcaacga cttcaccacg aaattctggg aattctacct 109080 tcggtttagt tactttcttt ccttgaagag cttgcagtac agctttcttg acagaagaaa 109140 cactatgagg aagaatgtaa gttgcataac cagttgcaat accggaaacg ccattaagaa 109200 gaacagtagg aataacaggc aaatagaaag caggaggaat gtgttcttta tcttgatgta 109260 ccggagcata ttcagtatct ttatatacgt tatagaaatt tttacttaca cgagcaaaaa 109320 tataacgact tgctgctgct ttttgaacgg tacgagaacc aaagtttcct tgaccgtcta 109380 acagaggaaa gttattattc caagtattag ccatcaaagc ccccgcgtct tgcgcagagt 109440 tttcaccatg atgatatcca aggtcagcta caccacctgc aatagaagcg agtttgtgaa 109500 acttatcttt atttcctcgc gccaaatcaa gagctcgagc aataacaaat cgttgaactg 109560 gcttaaatcc atcaatcata tttggaatag cacgattttc aaccgtgtac atagcataag 109620 ccagtgcttc attatcaatg atacttttta aatcgcgatt attcagttgc ataaatttac 109680 catactagtg aatgtagtgc cataataaca tcagaaatga aaagcacgac ttgaattaat 109740 ccgaacatta ctccataata tagtgctacc aataaagcag caagggctac cgagtagccc 109800 aagattttct taatcattag tagataacaa cacaaatgtt aaatatgcac acataccctg 109860 agctaaagct tgcgaaaaca cactgctggc atcaatacag atagttaaaa cacatgctac 109920 tatccaacaa ataaatgaaa taactcctaa taattttgcg atattcatat tttcctcact 109980 ggcgtccgaa gacgcctttg gttttaagat tgttacgata gaactgcatc acatgttcgt 110040 tatggaaatt actcattaat atgcctgcaa aacaaattta aagttatcag ccaacatacg 110100 gttcatttct tcaagtgttt gatactcaga atgatgatta cgagtaaacg ctaaagctaa 110160 ctgtcctttt ccaaatcccg tcgtcaaagg tttcatctta gaagcaggca gataaaatac 110220 cgtgtatgga acattgttat ttgcaatagt acgcgcaagc tgagaccggc gttgacgaat 110280 atgacttaga actgcgctga atccttgctt agatcgctga ttacctacat aaaatcgtgc 110340 agacacacat ggattactaa atggacgacc atctaattta cttactaaaa aataaaatcc 110400 aggtttagat aaaatatctt tatgcggagt tcccaaaaac cactcaccac ccttgattgt 110460 accaataaca gtagcgcctg cattgttcag atcagtaaca gtcatatatt tcatgttatt 110520 ttcctctaat tattttctac tccaaggccg catgaataca cacggccatt aaattactcg 110580 tcgcagtcga cgctcaattc ccagaactct tctacagtat aagtttcagt atcattttca 110640 atacagaaac gttcattact gttatttgct aaagtagcat taactgtcgg tttctcgtta 110700 gtgctcttaa gaggtgaaat acgaattaac tgatcaccgt tatctaaaca gaaaatttca 110760 ccaactttta catctttaaa aattttcata attcacctca gggagtataa aatccaaatg 110820 cagttgttga ccatcccatc caatatggga aatttgcacc aatgtaaaac ataagaatat 110880 aaaaccaaat gtttagtaaa ttcatcattt tacaccattc caaattgttt caaccacaga 110940 ttttaaacca ttttgatgaa tatcaattcc gactactgtc atcaaataga ttccaactac 111000 aactgaaccc aaggcgaaaa tcaacatgaa aatgaataaa gccggaaaaa tattatcgaa 111060 aaaccattcc ataaatgtaa aagcactgcg tttacgcttc atattttcct cacataaatc 111120 caaagtaagc gtttaataca tcaatcatta aaacgattgg gaatatactc aaaactacta 111180 gtattataac tacattccat atagctttaa caatcttttt cattttctgt tcctccgtag 111240 ttgataggat aataatacca cagaggaaca gtcttgtaaa caactttttt aaaaatattc 111300 gtaataaatg tgaataccaa tcactactgc cgaaacttgc gcaacccacc acgcacacgc 111360 aataagtaca gaattcaaaa ttttcataat aacctcatca caaaagtaaa tgttaaacaa 111420 attattggaa tactaattaa ccaaacaaaa caccaccata atgaactcat agttcaatct 111480 caatgatttc aagattattt tctttaatag ctttctttaa atcatcgtaa ataagaactt 111540 cccaagaatt gtttaaatca ccattcaaca aacgctcttg ttgcaattta tcagtaagat 111600 atggttggtc tgattcatat ttagacaatc ccaatgaaat aaatgatgtt gcatcgtcaa 111660 tttcagaata ttgtacataa acaaattcac ctgtgatttt atgtttaaca taaaagaatt 111720 taaatttcat ttttactcct ccgtagctga tagttgtata gtaccacagt ccttgtggta 111780 tgtaaactgt tttgtgaaaa tttttaaatg gaaagatacc atccgttgta gttgcttttt 111840 cttacaacct tacgaaggtc ttctctatca ccaatgaact tcggagtgta ctggatgaca 111900 cctggatgaa tttctttagt gttgaatata attatacagt cagcgacttg atgatttaga 111960 atgggcccta gatttattcc agaaccgtat ggatactctc cgctgcatcc ggttgttacc 112020 gaaatccaac gtgagtcagt ttgatgtgtc ttaacttcta cacgaagccc gcagtatttt 112080 ggatgcgcca gtacatccca cgcatatgta tacgggtcat taacatcctc ttggcctttg 112140 ttaacatacc cgctcagcca atctgctaca aaaaactctg catacacagc gatacggcat 112200 ctttcaataa cttctgcttt atcttggttc gggttttgtt ttaaagagta tcttgctgta 112260 tcagcaattt tgaccttcat ttcactagtc aagtcactgt tcgatagggt aaatgtcgga 112320 atctgaaata gtctctgtaa acccggattc gttttctgca tttagacttt cctttttacc 112380 gctgagataa gcgttatata ctttaagagt gccgtaataa attcggtcat tttcatctaa 112440 agactcacgg tcaagttcat cgagttcctt tttatccatg actataatat cattgcagta 112500 aagaaaccca agtttttcgt gaccaaactc aaatttattg cagtacacaa tattagcgtg 112560 atgatttccg tgcagtttaa tctcttttat gtcggaatca ccgatattca tacaataaat 112620 cataattttt ccttaaaaca aaagggccga agccccttat tttatttgaa ttgtgcaatt 112680 cttttctcta gacattcagc ataagatttc attgagatga actgtgaaag cagcagttct 112740 tgctcaactg cactaaccgt tagaaacttt gtgctttcta aaaatttact aagtgcatta 112800 attttgagca ttaattgatc gtattcttct tttactcgtg cttgataacc taacataatt 112860 ttccttagtt aagggccgaa gcccttattt aaattgttca gtaacgtctt caactacttc 112920 gtattggcag gtacgcattt tagcgtcgtt gtaatcaatc ggaattgata ctacatcgcg 112980 cggatgcact ttaactttta caactcgact ggttgaacta ctaaagtgac gaatataaga 113040 tttagaacac acatgcagac cacgagaaca agtttgtgta tcatcgtcat tcacacgagt 113100 acgtggcatt ttaactactt taccaggact attatcaaaa gtatttgaat gacagtcaaa 113160 gtaattactg cgaactactt tccaagcata gaagtaacca tcttctgtaa tttcaatatc 113220 atttgctacc aagaaatcaa agagtcgaga taccgctttt tggcttgggt tttccagcag 113280 attttccaag aacggaaaat aaaattcaaa gttttcgcct ttttccatcg aatcgagaat 113340 acgatcaact aaaccagacc gtaattcgat attttgatag aacaagcttc caccttcaat 113400 tcgaacatca ccggaaatat atttttcaac agcgcgacga acgttaattt tttgtgccgc 113460 ttcttccaac ttatccgcta caagcagatt aagaatttcc tggaagtttg aatgagtatt 113520 aggagttgcg ttataagtta caccgtcaac agtaattgaa atgaattttt tagatgcatt 113580 ccaaataatg tcagatttag caactggagc aataactgca tcgctattaa ctttaactgt 113640 aataccaccg ctaatagtaa ctttagggtg tttagcttct tcagcatttt tcaaaacacg 113700 acggattgtg tcaaccgata caccttgcca atcagccaat tcctgttggg tgtaattacc 113760 acttgaatac agtttaacaa tttcagcttg ttcgtttttg gtcaggcatt taatattgta 113820 cataattttc cttattaggc cgcaagggcc ttcatagttt tagcgatttg agaaacttca 113880 tcatcactta aagagttgcg atatccgatg aagtcggaaa caatacggaa tttcttggta 113940 aactcagcaa ccattttatc actgtttttt gaagcattat ttgataatac atcaaaaaga 114000 ttagttactg tccagatgtc atgaccgatg gtatcttttc caccattaaa atatacaccc 114060 tgtaatgaac taaccatatt agcgagtcgt gtatattctt cagaaacttc atctacactg 114120 aagtacttca tcataaaatc tagctcagga tacttgataa ttttatcaat atatcgttta 114180 gctgaacttg aataacctac atacttatca taatctacat catcaaaagc atctacatat 114240 aaatcacgca aagcttcaaa aatacattgg cactgaccga gttcttttac ctttttctgc 114300 aaaagcggac gaataacata aaattcatta atgccaataa gattagccat acgaatcaaa 114360 atattcatag atggatgaca aagagatgta gtaccatcca tagagaaaat atcagaacga 114420 tgcatatacg ctacataacc agtaatttca tctgcttctg atgtgagcgt aaatagttcc 114480 tctttttccc agcgcccgtc tttaatttca aacttaaatg ctgtagcagc tttaggacga 114540 ggagctttac ttttaactac ctttggaata taacttttaa ctaaagcttc aatttctgac 114600 aaataatgaa tgttaacttc atcactttca aacatcgcca taatatcagg gagtaaatca 114660 atctgcgatt ctacttctgg attaataaac agaagacgct cattgtgatg aatatttaaa 114720 gtgttattaa attcactatc atctaacgca tgtgctaatc cacgaacaat attaacacga 114780 tttttaatat catcaataac gatattaatt tttgttgtat taataccaaa cagacgataa 114840 cttgatgcga cggctgaagt ttcatgactt tgcttaatgc gtttcagtcg agggtcaaga 114900 tttacttcat acacaacccc tgcattgcat aacttactgt caggttcaaa catgctctgc 114960 atctttttat atgacagatt tttagtcgtg aatttgactg aattactaat catataatct 115020 cgagcagaat accccatctt catcaattca cggtatgtgt gacgaggaga tgtagattct 115080 ttaaatcgtt ttacatcttc attaaatgct ttctcactaa gctctttaac acgctcaata 115140 atatttttac gggtacgatc atctagtgaa agagcttcac gtgatggagc aatatcaagt 115200 gaacccattg gaaacttaat gtaattcact tcattgcgaa tgcttagcca gttacggtct 115260 ctaataacac catcaatagg ataaacaata ccgccataga tagcatataa tccaccacga 115320 tctggccagt atctttctgg atttacgccg taatagtcat caaaatcagg aaaataatca 115380 atttcacggt caagaccatt aatgatagcc aaatctttga atggtcgcat gatataagaa 115440 acttcataag caaagtttct aaagtctttt tcttcaactg gaactacgat ttcaatacca 115500 gttttatcgt ttggacccat ttcttttacg aatgtaggtt taatctgtgg gccatcacca 115560 tccatgtaag ctacataacc acgaatttca cctttatgat acgaagtaat actaaacgta 115620 tcagtataac taaacggaga tttagaacct aaaccaaatc cgccaatgaa atcgttagat 115680 tcagccttag atgaactgaa gtatgaatta tacaaaccag gagaattatc atcaccctga 115740 atatcaaaat cactcatacc cggaccaaaa tctcggcaaa caaatcgtgg atctaaacgt 115800 ccaggaactt gaatgataaa tttttcagga tttccattga gagcatgggc atcaatcatg 115860 ttggtaatca attcacggac tactgcgcga atcttgtttg tatacaaatc agacgacaga 115920 attttaaata ctttaggaga tgctgtgatg ctaaatgctt ttgatttaga accattacca 115980 agaattgttt ctttttcagt ggtgataatc ataatttcct cattaattca tattacgctt 116040 aataacttca gcaacttcta gtagttcgtc tttagttgcg gtgtcggatt gaattttatc 116100 tctaatatct ttaaagcggt ttttaaattc ttcggcttct cccatatcga aaaagcgttg 116160 aatgattcta tattctcgat gaactgcttt atcaaaaagt tctaaattta ctttatatga 116220 tttcatttca atatcctcat ttgcccaatt aattatacca catccttgtg gtaaagtaaa 116280 ctactggctc atccattctt tacgaaggtc agcattatct cccatgagca tttcaaaaag 116340 ctctttccag ttctcaggaa gtttaacaac atcatatact ggattttgaa tcatctcacg 116400 atattcagat ttttccaaag agccaagtcc cttaatataa cggatgctat gtttaggtag 116460 agcatctttg gcactctcat attcagcgac tgtataaaac cattcttgtt ttttaccgac 116520 ctgagcgatg attacaggag ttttgacaaa gcgaattctt ccttgttcaa acagttctgg 116580 ccaattacta aaaaatccga gcagagaagg ataaatgctt cctagaccat catggtcagc 116640 atcggtcata attgcaatat tatgataatt taagttttcg gctttttcac caagaactaa 116700 tccagtgatt gcgcaaatat caaacagttc tttgttttta agcatatcag catatgacat 116760 accccaactg ttgagaactt taccacgtaa tggataacca ccatgaagtt ctttatcacg 116820 aacatcaata agatatccga tagcagaatc accctcagtc aagaaaagag tagtgtcagc 116880 atctttaccg caaagattcg ctttaatatg tttatgaacc ttagctttag aagccttttt 116940 agctgcttta gtttctgctg ctttttctgc tgccaattta cgagccaagg cagcttcaat 117000 aattggcatt aaaattgctt cattatttaa aatagcacgt gaaatctttt tagcatcaag 117060 ctgaatatga ctgcggattt caccaaatgg agaagtcaaa cgctctttag tttgagaatc 117120 aaatcgcatg tttttcatat cacgaacaaa cataacgata gtcaaacatt ctttaacacg 117180 tgctttagtt acatcaattt tgaacttacg tttgatttgt ggaataaggt cttcacaaat 117240 atcatccata acacagtcaa tgtgatgacc accattctta gtatgaatgt tattgacgta 117300 tgttaattga cgaaaaccat ctggtgaacg accaaccgca atagaacaat tttcttgttc 117360 ttgaacgata gcatgttcat catactgtcg tgcatatttc ttaaaattgc cctgaacctt 117420 tttaccatta aaggtaaatt gaatatcagg ataaactact gcaagtgtct ggagacgatc 117480 tagtgtaatg tcaagataaa cttgggacag ctcattagtt tcaaatgaca taaaatcagg 117540 aatgaaagta acacgggttc ctttccattt tccaggaata gtttcccatg atttattttc 117600 catgccattt gaacaacgaa ctacaatatt attttgacca tcgccagttt caccgacaaa 117660 catcacagaa aaaatgttag ttaaactaga gccaacaccg ttcataccgc cagtgacgcg 117720 ttctttatca tcaccaaagt taccacctgc ttttggaata gtccaggcag caacaggacc 117780 aggaatttct tcaccagtag gtgttttaac catcgcttgt ggaataccac gaccgttatc 117840 ttcaactgtt acttgattgt ttttgatagt aacattaatt ttatttgcga atttaaactt 117900 agtacgaata ccttcatcta ctgagttatc gataatttca tcaataagct taacaagacc 117960 aggtacatac tgaacacttt cccatttacc aaacagaaag cgctcatgca tttcattagc 118020 ggaagagcca atgtacatgc cgctacgctt tttgatatgt tcaatatcgc tcagaatttt 118080 aatttcattc ttaatcatca cttatcctcg tttggtttcg ggaatattat actccggtaa 118140 tcataaagct aaaggcccga aggcctttta tttaaaacgg atagtcgaat ccttgaagaa 118200 tagaccagaa catactgttc cttctacttt ctgcccagta ggtccaacag cacgaaatcc 118260 agtgtgttgg aaatcatttt cagagcaacc gaaccagtta tatccagtga tttcaatatt 118320 agtaaaacca cttgaagaca aaactttggt tgcattatca gcatcagtac atcctactaa 118380 agacactgct aatactaatg ctgcgataga acgattaaca tatttcataa ttacccttta 118440 agtaagtcgt aaaatccacc gttcacatgc ttaggagcgg aaactaaccg aatagcaatc 118500 cgatgacaat caggacatac atcagtatcc ctttcagaaa ttttcttgat tttttcgtat 118560 tcttttgcac agtctttgga ttgacattta taatcataaa gaggcataat tattccttaa 118620 agtgagcttt caacatctga tacaaagacc atgcctgttc attattttca atagtaactt 118680 tcatgatcgg gaattcagat ggttcagtta ctggtgcagg gtcttcctgc tcttcagcag 118740 cctgatatgg attttccact tcattaaaga actcggcttc gttgctagaa agccagataa 118800 agttttcgtc aatgactgta cctcgtgatg aatatccaac tatgccagta gatgtcacaa 118860 ttttagtagg acgcccgtaa tagtcaacat ctaaaatttt aaaaggttcc atacctaaac 118920 gccgcgcata gattccgtta tcagtatggt ctttaataaa attttcttgg gcttgtttat 118980 ttttaaattg ataccattta ttaacttcaa atttaatagc cattaataaa tttccttcca 119040 gtaagttgtg ccgtcttcag taatttcacg aaatacacca taaattggtt gtttatcacc 119100 gactttctca tacacataaa cagaagtcaa gtgagtaaac ttgctagtat gttccttttg 119160 aactactacc aaatttggat caaataatac atcttcaaat tcatcattag tgcaattctg 119220 aacaatttta cgtttcatta caatttcctc attaattaaa cattggagcg atgcgtttca 119280 gaagagtatc agcacctttg gcgaatttcc attttattct ccaagttgtt ttctgtatca 119340 gtagttgata ttgatatagt accacaatca actactgatg tatatagttt tatgaaaaaa 119400 ttttaaactt tatgcacagc gagctttgct atagtgttta atccaacttt caggaatgac 119460 tttgtatgtt cctaaaaata ccgcgttgta cagcttaaca ccatcttcta cccactgatc 119520 ggtaatgtat gcacacatag cgcgagtacg gcgtttttga acaacccctt cctcatcttc 119580 agtaaattcg aattcataag gagcaacgaa cttaatagcc tgaccgagtt tccacttaaa 119640 gtctacacct acatgcgaag tatcaatcgt ttcaattcct ttagcaggaa cagctttcaa 119700 aaacgcagat tcaagaaatt tcgcgcgaac ataaccaaac tgaggtttag actttccatc 119760 tttaggaatg atacgcactt ttacttcaga atcttcatct ttaacgccgc gtttaagctg 119820 aatgcttaca atttcgacca attttcctgc tgctttagag cgggatttat cagatacacg 119880 agcaatttca ccaatattaa taatcatagt tatctctcac ttgttaaaaa gattttatac 119940 tccacaggac cattatactc tggtcccaag agtttgtaaa ctattaattc aaaatagcta 120000 ccaccgcact acgaggtact acactaaaat ctcctgcatg gacaacgttc agaagctcaa 120060 caccatcttc aatccactgg tctgttaccc aaccacagat aggattatca aaaggacgac 120120 ggatagacac agcagcacac aacaggtctg tagggtcttg ttcttcaact tcttggaaca 120180 ggatgaactc atcttcataa accaggtttt tctttatttt gttattatct aaccggcgac 120240 cgtggatgac gtaagatttg tcaaaccact cacttttggc aaattcttca acaataaatt 120300 cgccttcgcc aaaaacatca gtcagagttt tatgaccaga aatcaaggca ttagttttaa 120360 ttttaggttc aaccagtttg taggttttgc cgatttcaat agcggtagtc atagtaggtt 120420 ccttaatttc cagtggttta acagggcata cataagtgct tacaacatca aaatcaatca 120480 gtttagctac cggattcggt gtgtattcag gattataatt aaatttcata attatctcat 120540 ttcaataaaa tctacgagtt cagcatggga tttgcggaac attacttggt gtccaccaat 120600 gacaacttga tcatctggca cttcgtatac agcgagataa aatcctttag aagataattc 120660 ttcccgctct tctcgcgtga accatctcat catatcatat tcactagcga aagcaaaatg 120720 ataaagagct ataaaccatc ctggaatatg atattctact ccaacataat ctttcttgaa 120780 cttagtatta attgctatat tagcgttttt aactaataat ttgtcttcgt gtggtaaagg 120840 aattctttta ttattatcgc tatgatgcat aaaattaggt ctgtcataac ctacgtgtaa 120900 tagccactct tcgctccata aatctattat actcctgtac ggcgttattt gaacacaaag 120960 atttcgacgt attgttatag catcttcatt attaagaata ctaaacgatg attcaacacg 121020 ataaattttc attttattat cctcagtagc tatggtgtta taataccaca actaaccgag 121080 gaagtaaaca actttttatc gttttgttgg aagagataga ggatcgcaat cttcctctga 121140 cggagcatct tcaagaccca tagcgtatcg caaagcatac ttcatcatca ggatgtcttt 121200 cgcacagtca tgaatagaat tatgcgcaac aaatccatct aaagttccct ttggaagggg 121260 gcatgttgtc atatcacgaa caagcagaag tgcttcaatt ctggtacgaa tatcacgctg 121320 attccagaat ttacatggtt ctaacttaaa tgtgtcaagc tcattctcag atacaccatt 121380 aaggcgttga atatcacgaa tgagatcgac taaaattgga aaatcaaacg acattccacg 121440 gcaccagcct tgagatttcc aaggatcgat gttatgtgca ttgatgtaat cattaaattt 121500 tgcaatacca tcaatggtgc ttacatcttc atctgatggt gcaatgtttt ttcgagcttc 121560 aggagattga tttttccacc attcgatagt gcttttagta aaaagacgat gtcctttttg 121620 gctttttaaa tcaaatttga ttttaatgcc acgtgaaact aattcatcaa atgtttcaac 121680 tacttctgga ttagggtcaa aggcaataac agccaaatca ataacagctg ccttttcacc 121740 acttcccatt gtttcaaaat ctataataaa atcaaacatt aaattttcct tgctaaatcg 121800 cgaatttgac ctacagtata gtcttgaata taaactttat taatgggctc atcaataaat 121860 tttgccacag attcaatgtc tttttgtatc tcttcaagac tgtatactat ctttgaagct 121920 ttttcgcgaa tagtaatatt ttcaggacct ggattttctt caatgacatc tttaacattt 121980 gttataagag atttaaactg ccaccaactt aattcaatca ttaataatcg cctcataaag 122040 atagctaatt tcgcctaaaa cataatcatt aattgtaaca gttttcactt caccgcaaaa 122100 gaattctaac gcaatcaaat ctcgttcaat ttcttctaat tgaagcatca acttactaga 122160 ttcaattttt acagttttac gatttttacc atgagcaatt tcataaattt cgctaacttt 122220 atcttgaaga agataaaact gatctttagt tatttccacg aatagcttcc tcaaatttaa 122280 tcatacataa aatacatcat aacgaccacg ggtaacacca acataaagaa gttgttgggc 122340 caattcagca tctgcataat gaatgcaagg cgtataaatg aaagcacggt ctacagacat 122400 accctgagct ttatggaatg ttgatgcagg aagtgctttc actttactaa actgtgattt 122460 agcatcccaa aaatcactcc acggagcttt tccaccttta ttccaatttt tgtaagtttc 122520 tgcagtttta cctaaaaata agttaaactt atacagctct tcatcagatg aaattatttt 122580 aatcttttca cgataatatt catcatcgcc gtaagtttct actgttaaat cccaatgacg 122640 aattagatat tctccagaaa caccacgagc tttaacaaat gttgatgtat actctgcttc 122700 tataatacga actaattgtc cgttattaaa aataatttct gacacaggct ttccatcaat 122760 tttatatgtt ttaattaatg gttcctgcat tacaataatt tcaccgacaa taaaatcttt 122820 atcagtttca aaaatctttt tacgaataat gctatttaac ttatcaacag atttattcgt 122880 aaatgccatt acacgatttt caaacaaatc atctagagat ttgacgattg aaaaataatt 122940 taccataaaa tcgcgtaaag cggtatcacc tgtaaatcca cgtactccat gcccgtcaac 123000 aactttatca taaatccact taccgttgcg aacgtcagta gctacatcaa taataggagc 123060 attactgcgt ttaacttcag tgagttcaca ctgataaaaa tctttgtgtg taaagaatgg 123120 actgatataa gcagtgtttt ctcctgggtc aacaggtcta atttgcttat tatcccctat 123180 tccaattata gtacaccaag gtggaatagt tgaaagcaga attttaaata gctttctatc 123240 atacattgac acttcatcgc agattaatac cctgcattta gctaaatctg gtacttcctt 123300 ctgctcaaag aggacatttt cttcatatgt tactgggtta attttaagaa tactatgaat 123360 agtactcgct tctttccctg atagttttga aagaatcttt ttagctgcat gtgtaggagc 123420 tgctaaaata ataccagttt cacccgtaga tattaaggct tcaatgatga acttagtaag 123480 agtagtctta ccagtaccag caggtccatt aatagttaca tgatgtttct tttctttgat 123540 agccctcata acaatgttaa aggcattttt ctggccttcg gtcaaatcat caaatgtcat 123600 cgtaaattcc ctgcaattgg tatactaaca atacgcccag tatctaaaat tcgccgatat 123660 aatctttgtg tgtctacatc aggcttaaca cgtttaactt ctattttatt aaaccaaaac 123720 ttgcgtggag tctcaactag tcttggaatt cccataccta aagctagtcg atactgctct 123780 ttaagagtgg taaatacttt atcagcaata ttccattcaa aaaatacagc aggacgatgt 123840 tcatcaagcg gaactggcgc cgtaaatcca tctttatctc tataaactat cgcatataca 123900 taaaccatat tatcctcgga taagtttaaa aattgaacaa ttcagcggat atcctctttt 123960 cagtttaagt ttatcaataa aagacaagtt ttgataccgc tctacacctt gaataatttt 124020 atcacacata tcatattgca tttctgcttc tgacaacttt ttcacagttt tccaatcaga 124080 gcctttaaga agaacgttca atttaacagc ttcagcgcct tctgctatac gagaaccatc 124140 aatacgagct ttaagtgcta caatcgttag cttaatatca gaggtttgtt ttgatttaga 124200 aagctgagaa atgtgttcaa ttcggttttc acgttttttc tgtatagctt taatttgatt 124260 ataagtcttt ttgattttag cccatttctt ttcatctaaa tttagtttat gaactttttt 124320 cgcagatgaa cgaccaattc gcaaagcaaa taaatcacgc ttttcgatca actcttctaa 124380 agtataatca gaacgaaatg tattatactt tttctttact gcaataacat tccctttaat 124440 gtatccaacg ttattatcaa aacgttctaa tgataatttc tctccttcaa tacgattatc 124500 aaaaggttct cccgagtaag cacaaacttt ctgatctaaa atgttcttaa tgtaattgaa 124560 gtctaagtta aaatctttag aacgtctttt agcagatgcc tgagtgtgct ctagacgacg 124620 tgtaatttta cgaatttgat ttttagacag tttcatattt ttctcacgga cgggttaact 124680 acttatacta taacattttt acttcagttt gtaaacaact ttatgtaaaa atgctttaaa 124740 aatttcatgg tataatgaat ctaagtcctt ccattataga ttaaatcctt caaaatcaag 124800 agtatagata gtgtatgttg aatacttttt gtactcatat ctatctgcaa ttctaaatac 124860 acttccagct ggtatcatta cttcttgttc atctgaaact aattccatat tacgataacg 124920 atggctatct ggaaacttaa aactcggact atattcttta caacgtaaag cttttatagc 124980 atactcctgg aaattaaaca ccataggagc tttgaattca aaaataactt gtgtgttata 125040 ctctaaaccg gaagcaaaat gtagagctat atttttatca tatgaagctg atactacttt 125100 atcaaatgta ataatatcaa ttccttgatt taacacctgc ttagtctcag ctggaacacc 125160 tctccaaaga ggtttatcgt ttagaaccaa acgagatttg attatttcat ttaaccaaga 125220 atgatcgtct ggcttattag taatacaatg aattaaaagt tcaatttcag ataaattaaa 125280 tccttcagaa agtaattctt cacgaataga agcacgcacc gatgcatcca ttgattttat 125340 tttaaaatct tttagttgca ttactgagta tttcattcaa ctacctcaat atcataaact 125400 ttaaatgttc caaatgaatc gtgtaatttt tcttttgaaa tagaagttat tctatacttt 125460 ccaattggaa tcatccattc ttgttcacgc acaatcatca ttaagttatc agtacgctct 125520 gaatctaatc catcagtatc ttcatacgtg tacttaaact cagtattagg agaagaaagt 125580 ataatatcgc tgatatggtc agaataatta aaagctttat cagtttttaa gcgaaatatt 125640 atttcagtga aatactcaac ataagaaaaa ccacatgctg tgagtaaact agtagtaaat 125700 gaatctaccc tgttcgttga aaacacttct ccaacttgta aatctttaat aagttcttct 125760 gttgattttg atataccacg atataactga tatggtgatt tagttaaatg ctttttaatg 125820 attttattca attgccgatg aagagcttca ttctttttag cttccataca ttgccaaaga 125880 acagactgct caaagtcagt aaatttttca cagacttttt tatacatatc atattgaaaa 125940 tcaacgcttt cagcttttat agataactgt tcaacatctg caagattaat aatcatgata 126000 gcctccgtat acttcagaag ctatcatatc atcgttagaa aggaaagtaa acaacttttt 126060 gaattatttt gcccagggag cccaaggcgg agggtcaaga tggtatgaag ctagttcttc 126120 tagaagagca tctggggctt caattccata attctgtaat actatacggt actctttctt 126180 ataatcacta gaatcattct ggttattcgt agaatgatta tcttctaaca tctcaaataa 126240 atccatatta attcctagcg ataaaaacca aaatgacgat tagcttcagc aatctttctt 126300 tcttcttcgg acattctcca gcgtagtcca acatcaaaat gagcccagac catcctaaca 126360 aatgcattta tatctttaat atcttcaata atgaatgttt tacttttaaa aggctgactc 126420 gctaatttaa ctttatcatc ttcaaacagg tcaaaaagga ccatattcat gagctctttt 126480 atagccttta atagttaaag cttcagaaga agaaaacggt gaatcagtat tctgcaaaat 126540 atcttcagta tgctttataa ttagaataat attttctgga tattttcttt cttttatatc 126600 tttaattaaa atatccggat tttctgctaa aggaataatc aatgagcaat ttttatcaag 126660 cgtatttact gatttacctt ctttagacat aaattctatt gaatagtgtt ttgctacttc 126720 aatcatgtga tttccttttg cctactaatg gaccatcggg aattttgttt tcctggatat 126780 atttctcatt ttcttccatc attttactgc caattttaag aagcaaatcc agtgcttcat 126840 ttgctttagc cttggcctct tctaacgtca tatctctgtt cacgatttat ccccatagat 126900 gtctctcatc aatttaagcg ctgagcgttc taatttcttt tctttctcag cactaatcat 126960 tgatttcatc cattcttctg attcattctg catttcttta tttgcctgtt caacccaacc 127020 atcatcaatg tacattgagt ttggtctatt gaaccattca aacattttct tcagaacttt 127080 catttacttt acccaaaaca acagtaggag catcatcaaa ttcatgaatt tttagcaaat 127140 ttggatgtaa actattccat atagaagaaa taaagtatga taaagcatct tcactcgcaa 127200 ttataaattt atttccttta tctattttcc aactatataa tgaatcatac gaatagaaag 127260 ataaaggttt atcattatat tgttctgcgc taacattaat gtattcggat ttagtaaatg 127320 cttcaattgc tctaaatgga atatttggta cagtttcaat aataccaatc tttttaagct 127380 ttatttcagc atcttctgga actggcattg aaacgaaatt ttctacgaga tacattgggt 127440 cacaataacc cttatcaatc attactgcta cggtaattgg aacgtcttta gcaaacgaca 127500 tgctatcact gctaatatac atttcaaaca aaatcgcttc cataattttc ctcaatcaca 127560 ggatgtagat gaacaactag aatcacaaga acttccacat gaatcgcccg tccatacatg 127620 aacaggaaca ttagtatcat atgaatcaga attagactgt gtattctgtg tattagatga 127680 tgtagtaggt gttgaccagc gccaaggatt tttataatat tcttgagctt cttcataagt 127740 catagtaact gcttctactg ttccatctcc catataaaca tattcaacta cagttaaagg 127800 aaggtagtcg tttgaaatag gaactacacc ttctccagga gctgtagaga aaaaatccgt 127860 aaagaaattt ttaaaccaat taaagataaa cattacaaaa agcctctctt gaattcaact 127920 tgcttctcgc cataatcata tcgaatctct gcattaaatt cgacagaacc atctgcgtac 127980 atcataaatg aatgcacaac aacttctgta gaccatggct gtagttcgta tttcttcatt 128040 acatgccgtg aaatgataat atctaaatct tcatttggtt taatccaacg atttaacata 128100 gtgctctcct ctataagata attttattat accatactca ttttggaaag taaaccggta 128160 aaatgaaaaa aggactcccg aaggagtcct tgaatttatt caccagttac tttccacaaa 128220 tcttcgtttg cagtaatcca ttcagtacgt tgattttctt catatacagt agtatatgct 128280 gctttttctg aagggaatat ctgataatga gcgccagaaa ttttgtgaac gtcagaataa 128340 agagggaaag ctacagaaat ttcctttcct tcaattttct tatttccatc taatttctgc 128400 tcaaatgttt tgatattaac ataaccgcga gtactagcca tgtaattctc cttttattta 128460 aattacatga ttatttataa taattctcgc ggcttttaag tcgtcgttta aataaacgag 128520 ctattaataa cctcggtctt gacgcgcgaa gttttcagca tttttcagat aataaagttt 128580 aaagatttct tcagccgtaa gaccaagacc ttggaacatg ttcagaacga aatgaagaat 128640 atcaatcatt tcgaatttaa tttccaactg gtcttgtgga gacaaatcag taattagagt 128700 ttcacgacgt tcaccatgct gcgacttcca aggcttccat acagcagatg catctttttc 128760 gccattgctc ataccgccaa gagaagtcag aagttcacgg aattcatcgt caatataatc 128820 tttctgatta cgcagccaat caacaacttc accagcagta gccaaatcat caggatgacg 128880 gttatattca ggtttatctt tagctaaacg aatctgcaga gatttctgca tgtcaagcat 128940 tacctgcagc gggtcttttt catcaccaag aatatcccag tattcatttt gagctttatc 129000 agcgccttcg atcagttgac tacattcgtt aaagtaagcc attatttttc ctttcaattc 129060 attaataagt taaataatta tatcatttga atatgtaagc aattaattaa aaatatatac 129120 ttcatcagtt ccattctttt ctttggaatg atatatgtta aagacgtatt ttttattaag 129180 atgcttaaca ttatattttt tagaccattc tttaagaaga gtgttttcct ttccgtgatg 129240 ctctaaaaca ttcgacagtc caaattttat tcctctgtca tttaaagagt ctaaaagatt 129300 taaaaggtct ttttcttcat cttctgacca aaatttatta taatcagcaa ctgttataag 129360 atatggaggg tccacatata caaaatcgcc gtctagaatt ttgacatctt taaaatgcaa 129420 tgaactaaag attattttat cacaattttg tttaaagtga ttaaagcgtt tttcactatt 129480 tttgtttata gttctttttc caaacggagt agtaaaattt cctttatcgt ttatacgaat 129540 catattacta aatccgtgaa aatgaagaac ataaagtaaa agaggatctc tagttttatt 129600 ataatcttca cgtaatttca aaaactcttc ttttgatgtt tttgatagtt tatagtgctt 129660 tattactttt aaaacgtcat cccatgatac attaataaga cgcttataca tttcaataat 129720 tggttcttga atatcattgg ccaatacagg accattgacg ttcaaagaca ctgataaacc 129780 tccacaaaat aaatccacga atctgtcata ttttggaaag tgagacttaa gttcaggtaa 129840 taatgattgt ttattacctg tatacgcaat agctcctagc attatattct ctcatttatt 129900 gcagcaaaaa acgaattata taattcttca tcatatgtat ttgatagtaa tactaacacg 129960 ttttgtgatt tagcatattc attaaacctt gcttggatgg ttggattatc agtaaatgat 130020 tctctttttg tccatttatt acgtggataa tatccgcatg gcaaaaaatc taatatcatc 130080 aatgacacag ggttttcagt ttttgtgtat tcttttaatt tctctttatc ttctaaatat 130140 attccaaccg aatcaatagc tgtacctcca ccaacttggt gtttaatttc aattatatgc 130200 tttttaccat tgcgagaaat gacaatatca aatcttctag tacgcttctt agttgtaaaa 130260 ttcgaacaaa acaaattatt tgatttttca gtatcgtcgg ttaaaaccat tttttcttga 130320 taactaactg aacaatcagt gaaatattct tttactttat taagtatgaa attttcaact 130380 acggcagata ttttatatga atctccattt aaagccattt catgcacaat tttattaatc 130440 atcatatcat cctcagcaat ttattttata atatcataac aagctgagaa agtaaacaaa 130500 tttatgataa atattaattt aaaggaggac atatggtaca aaaattaatg gcacttgtta 130560 atgccatcaa aggtaataaa aggcgcatag cttttactat ttctgctatg ataggaattt 130620 tactttggaa ttttgtttta tcgccagttg ctattgctca tggcgttagt attccagtag 130680 ttactcttga tacattcgta gatttagcat ttgctttagt tgggttaatt taaatcttag 130740 catatttaga tagccgcatt ttagccatca acccctgtgc aatattattt ttcatatatt 130800 ccataatttg ttcaggggtt gcaccttcct ttctaatcat atcattaaca tcttttgatt 130860 tccagggaga tttatcccaa aacataaccc tttctcctgc atcaactaat ttagtcattc 130920 gtttaatagt gtcaggatga cgaggttcat tatctaaaac ccacactcgt ctatctttaa 130980 atggaacaac ttctaggtct aattgaccac ccgtaatagc tataccattt tcaataaaaa 131040 gtgaatctat aggtccttct agaacatata catcaccatc tttaactcgt tcgactccat 131100 agatttttgt tgcctcagga taagctttga tggtgatata tttttgagga gcatctttct 131160 ttaatgcacg tccttgaaac gactcagctt ttccattagc attataaatt ggaataacaa 131220 gacgaggctc aggtatttcc tttttatatg ttcccggtgc tatgctatta accaatttag 131280 gccattcggt tgtaaaccaa agatatttcc atttatcctt tggaatacaa cgagctttta 131340 catattttat aattgaatgg tcttccgcca gtttatctaa tctaacacat gacggaagag 131400 atttaattat tttcttctca ggttgtttag gaagttcttt aggtttttct actggacgac 131460 ttttaccttt ttcttttctt atttcaaaga tatactcacg atataaatca ggttcaaact 131520 cctttaaata tattccgatt ggtgcatgat agttacagtt ataacaatga atatttcctt 131580 cattattatc accataatac catccacggg ctttattttg gtcggttttt gaatctccac 131640 acactgggca tctaaaccgc aatttaaaag ttgaactatt atttacttgt gtgaatttag 131700 gtaaatgagc taatgcacgg tatgcaaact cattatcaat ccaaggtatt gatgacattt 131760 ttactcttct ttttctttag attcctcttt tttcttttta ggaatctgtt caggaccttt 131820 atttactaca gcgcccgacg ttgttccagt agagatattt tcaggattac cacctgaatc 131880 tccagcgacc atatcttctt tgataaattc tttaaatgtt ttcatattaa cctctattca 131940 taaaagcatt aaaaatttgg tcatcaatag atggaatagc aaccttttcg gcatcattta 132000 gcaaatcatt aatttcatca gatagcataa cacatgtacc tttatttcct gtaattgtta 132060 ctgcacaatt acgaacgttt tctttatcaa attttaggtt aatattttcg tagtgaaaat 132120 cctttaatgc cgaatatatc tttaaaatga aattgtcttt tactacaata aacccaacct 132180 cactattaaa acgtggttca tggaaactgt aataaacctt ttcatctata aaatcgtatg 132240 aaattttttc catttttaaa tatgaaaatt cagaactata catattaacc tttattcata 132300 aaagcattaa aaatttgatc gtcaatagaa acttttactt taggctgttc ttcaaacgtt 132360 aattcatatc cacatattac aattttgtga tcgataccaa aatacacaga agcaatatta 132420 ttaatattat tttcagtgaa atctaaatca acatcaatat ctttttgact aacgctcaaa 132480 ggataattaa tacgaataat tcgattatct ttaacaaaga ttccaccgac atactctgtg 132540 ctgcgtttaa agtttacacg tttcctaaat gaaaaatatt caggttcttt atgggctcga 132600 ctcatagggc ttaaagtgta ttccgaatat gaaatatcaa atcctacacc ttcaatatga 132660 gccaaagtgt catgattaaa ccaattataa tcgtatgcca aatccattaa attgtaatat 132720 gtgaaaggca ccggattaac atcatatgtt gtacctttaa aatctgccca ggcaacgatt 132780 tcgttatctt taacaattac aaaaattgtg ccaataagat atccacggtt attttcatca 132840 ggcgttatat tataacattg tgcatcagga aatttaccgt atttaaacgg tggatttttg 132900 tgcatataat aaatcatatt attcgcctgt gatttcggtt acgatatttt tattattaaa 132960 gtttttatcg caatacagaa cataattata ctgcattaca ccaccagact taagctgttt 133020 ttgcacttca gctttcattt caggacgatc acgcttaacg atattcataa tatctgcttc 133080 aatttgagtt tcaacctcag tctgatccgc agtcatagac cattcacaca aatctttatc 133140 ataacctgcc atagcaggct gagcagcaca agaagctaaa gcaaaaattg cagcaaaaac 133200 aaattttttc atgattaatc tcctcagtag tttatgttta tatagtatct caatttccaa 133260 taaaagtaaa cagttatttt aaaacttttg cgtaatcaca tgttacaaac tgtttctcta 133320 gcttaacgat cttacgaaaa taccttttac actgacgaat ctgtcgcttc gtaggacgta 133380 cagcaaactt aataaattcc actcgaccaa atggaggact ttcttctgct ggaatatcta 133440 acaccaattc ccacgtatcg gcaataagtg ctttgaattg cgtatttttc ctgacgttat 133500 acggagtagg tttaaataaa acaatatgca tattatcctc ggcaatccac ttcacatact 133560 ttcttgtcat caatgaaagc tttaactaat gctttattaa cttcagcata ttgagtagta 133620 gcccattgaa cgtcatcttt catcattgtg gtttctttag taaacatgct ttcattctta 133680 aaccacccca taaaaactac ctttaccaat tccataacaa tctcctcatt taaccaacaa 133740 gactactata ccatagtctc gtcagcttgt aaactaaaat tttaattcat ttgccaaagc 133800 atctaactgt gctcgagtgg attcatttct ttgatagcga ttctgttcag cctgaatctg 133860 ttgtgaacct gctacttcac tcacttcagt tggagtagaa tcttgttcaa tttctaccca 133920 tttctgattt cctttttgaa cacccatcaa aaacttattc catttattct tatcaccata 133980 tcgtgatttg atttgcttaa tgagttgttg ttcagcagct gccaactcct cggtttcaat 134040 gaccgcaagc ataaaatcag ctgttgctgg aagaccagca gattctgcaa tatcgctcat 134100 gttaacatcg gaagagtccc aagcttgttt accaacctgt gctgcagtcc aaagaacagt 134160 ttcggtttca acagccagag cacgcaattc ctctgcaata gctttaacag ttgtgtaact 134220 attttctgaa taaactctaa tgcggcaaga tttacaaata cctagatagt cgacaataat 134280 gattgttgga acaaaattct tcttgagctt taattcattt aaaagtgatc gaaatgtatt 134340 agcgtctgct ccaccagtag gatattgttt aacgattaaa cggccgaggg tagatttctc 134400 acgccatttt tccatttttc ctttatattc agcgtaagaa atatgcccat catcaatgtc 134460 atcaagagaa acatcaagca tattagcatc aatacgctta gcacagactt cttctgccat 134520 ttccatggaa atgtaaagaa cattatgtcc gagctgcaaa taatctgctg ccaatgaaca 134580 caatcctaat gacttaccaa cgttaacgcc agccattaaa acgttcagtg ttccagtctc 134640 agctccgcct ttagtaattt tgtttagaat tctgagttta aatggaacct tacgagcttt 134700 attcatataa gatagccaac gtgcttcgta gtcatccatc caatcatgac caacgtaact 134760 atcaaatgaa attgataatg cttggcgcat gatgtcagga atagcaccta catctggcat 134820 tttcttattt cgtttttccg gaggaagctc agcattagtt tgaatttcaa ttattttaga 134880 cgtagcatta aacatcgccc tttgctgaac atatttttct gtttctttta ctaaccagct 134940 atggtcttct ggagaatcgg ctagtttcga aataagtgtt tttacaccag aatattctgt 135000 ttcagtaaat gaactatttt ctaatgcaac atttaacgca ttaatagatg gaacgctatg 135060 gtactcatta acatgagatt taattaattt gaatgtattt ttagctggac cactttcaaa 135120 atattctgaa tccatatatg gccaaacttt tgaaaaataa gcttgatcaa atatgagatg 135180 ggaaagaata atttctacca cacttactcc ttaaaagaat ttaaactttt tctttgacct 135240 tttattgaat gcatcttgta gttgcattgt aatacatttt tctacatgag gagctaactc 135300 agcttttctt tcttggtcaa gaacagcaaa gtccattaca acctttccat caacccaatc 135360 taattttgtc acatacacaa tgtgtgtaga accatcttct agtttaatga caatctcctg 135420 gataacattt tccatggcag atttaattat cttaagagac tcattaaaaa gacgttcttt 135480 tctttcttct tccccctccg aagaggggga ttcatcgata atttctagat ctaagtctaa 135540 atcatcttta ttcattaaat tcttccatat cacttaactg ctcgaggtca gtttctaaat 135600 cagctgctga tttactttta ctttctggag atttaaattt ttcaaccttt gagttaatca 135660 attcatcaac ttcagcttca acaatttcat tactatcaat agcacctaac tgataagcac 135720 gtttaatagc atctcggaat ggttgatgct taaataaagg accccagaat gtagtgcagt 135780 tggtatcttt tgcacgccaa gatttttctt cgcgaatcat ctcgccggtt tcttcatcaa 135840 gaaattcacg agcataccag ccattttttg gttttactac aaatcctaat tctagagcca 135900 tatctaacaa tccagaataa ggatcgatac caccgtcaaa tttaacatca ataaagaatt 135960 tacttttttc tttaacggta cgagattttt ctacatttag aacaaattga tacccctgaa 136020 gatcagaacc atctttaatc tgacgcttac cgataatgaa tacagtatca gccgaataca 136080 tcggtccagt accacctccc ataactgttt tactaaacat ttcttgtgtt tcgtatgtat 136140 ggttaatagc aatacatgga atatttttag tactaaaata gggagttacg atacgaaata 136200 agcttttcat tgttttagct ctagtcatat cactaacaac tttttcattt aaagcatctt 136260 cagtttcttt cttagaagct aagttaccaa gtgaatcgat aaaaacgact accttttcgc 136320 cacgttcaat tgcatccaat tgattaacca tgtcaatacg taattgctca agtgattgaa 136380 ccggagtatg aattactcgt tctggatcga ctcccataga ccgcaaataa gcaggagtaa 136440 taccaaattc actatcataa aacaaacata ctgcatcagg atattgacgc atgtaagatg 136500 acaccattgt taatccaaag tttgatttaa atgattttga tggacctgcc aaaattaaca 136560 gaccagattg cataccacca gtaatttcac cagaaagtgc aatattcatc ataggaattt 136620 ttgttcgaac tacatctttt tcattaaaga atttagatgc tgttaattct gcagtcaatt 136680 tagaagtaga agctttaatc aaacgggatt ttaaatctgc aatagacatt cattttttcc 136740 ataggcatca ttatattttc ctcactggtt aaagataaag taattataac acaataaatt 136800 taggcattaa tcaactgcta ttggatgaat agcattaaac ttatgaaatg cttctgattt 136860 ttctttacgc gaaacacaca tgcgaagaac ctttaatggc tcgtcttctt cacccaacga 136920 ttttcgtttt tcaatatttg aagttttcca acgagcttgc tctggaaact ctctattgat 136980 ttgctcaagc gctctattat gtttagaatt actacgaatt gaactacacc caccgggagc 137040 gtgtgatttt ccagatacaa ctagatattt gaacaaggcc aaatgcggat aaccttgatt 137100 aattaaattg agaaatgcat acatatcttc gcataaatca atttttccat acccaatttg 137160 ttctgccgta agttttccga ggtcatacca tgtattcgtg aatccatatg agttttcacg 137220 ataattaccc caagatgaag taattttaaa aattggtaga cgagcatgac cgtgataata 137280 cccgcaatcc atggcatctt caacgtattg aattaattca tagaactgtt cacgagttaa 137340 ttgattaatt ttatctacac gccgtttatc gtctctcttt cgtattgaac tcatacgaat 137400 agtagtatca tcatcaatca tccagattcg ttgacctgca tacatatcag taattgcttt 137460 acgagtaccg gcaattccat taacatcatc aggaatagtt acaattttag ctctagaccc 137520 ataagcatca taataagctt tttcttcgtg ttcacgcact acaatatggg gttcataatc 137580 agtcggaaac atattaaggg cagaaactgc ccctacacgc tgataacttg gaattacgaa 137640 ttgaatcatt tccactcacc gttataatct tttttcacaa tatgagtttc gccagtattc 137700 caccaatgat caaccaagta aaaatgacga gaatatacat gaagacttcc aacattccat 137760 ataatagaac ctgctttata ctgacgagtt gaatcgcctg cattcaaatc agatactaat 137820 ttatctaata cgtatttttg ccatgcataa tcattacgga atccgaagac cacgtcattt 137880 gagcgcatgt taacaaccgc attgactttc ttatcacgaa tcaggtactg tactgtatta 137940 gtacacatga aatctgacat accatcttta ttgtagtcaa actgcataga tggacgagta 138000 taaatcatga taccacgtcg agaatcagga ttttgaccaa gttcagctaa acacatatca 138060 tactgggcat agttatcttc tgaccagata gcccaaccat aattcgagtt aatttcacct 138120 ttagaagatg ctacttgttg ccaaatcttc ggtgtttcac ctggaatatc tttaacaaac 138180 agactttgag acttatacca ttcaagttca cgctgaatgt attcatcatt aagagcgcca 138240 aaaataaacg gttcatctgc tacaaatgat gcgccaataa tttcaatagt tttaacaccg 138300 gttttatcaa ctacgaaatc tttttctttt aatgcaagcc ccaaatgaag acggatttct 138360 tcaactgtca tagagtcact aatcatttaa acctcaattg atacattcat atttaacttg 138420 taacagtaat aaactccaac ctaaaataat agttggaatc ataagaggaa ccgttacact 138480 atagtatata cttattataa ccatcaagat taaaagcaat gctgttataa ttttgctttt 138540 cattccttct ctctgatgat aattacctga tttggctgcg cagacttttt agtttcacct 138600 gcaattgacc aaataaatgt aataaaccaa ccaataattg accagttaaa cagtaaagat 138660 gtgaaaaaga ttcctactgt cgattttgac ccacgcatca aggcgataaa ccatggaagc 138720 atgtatataa taatagccaa cacgcctgaa actaaaacca taaaaattga acctgctact 138780 aaagtttcca tgttttcctc acttagtcaa attttttaca catgaattat aagaattcac 138840 tacatactcc atcggagcat ttttacctgt acgccattgg taattattag cccaattagc 138900 ccaaagttcg gcacagtagt tttcaatttt ttcttcgtgt gtaattacat ctgaattacg 138960 atacgcttga gcagattcat ctggacgaat agcttcgtca aaattcgcct gcatttgttc 139020 tactgtctgt tttggagctt ctttatagca cttgacatta ggattataaa atttgcttga 139080 acagtttaca atttttccta catcagactg atttactacc ggtccttgag ctacacaacc 139140 agtaagacct aatgcaataa ccaaaatagc gattttcata ataatttcct caaatacaag 139200 tagtaattac tccagtagtg cttacacaga tattacctaa ttgaacaccc agcgttccat 139260 tagtattcat atgaagatta tcatcaattt ttgttgatac tttaccattc atgtgaataa 139320 cagtattaga ttcaatcaca ttctgagtat cattttcaat atcaataaat ggaacagctg 139380 ctaatgcaac taaacacgct gctaatgcaa ctaaacacac tgctaaacaa ccataaacaa 139440 ttttcatttt attctccaat ccatatcagt tgatagttgt atagtaccat agaagaacag 139500 ggatgtaaac agttttgtga aaaaaatttt tagggaatcc aaagggtcca gaatcatctc 139560 tttttcataa gtatagattt atattacttg tatgaaaaag ggacctggag gtccctagat 139620 ttattctatc agccaaacag gaagtctaac gaagcttttt cttcatagtc catgccagcc 139680 gattcacaca tacctgcaag cggtttaaca aacgattttt ggaacaaagt tgagtggtca 139740 atccaagata gcacatcaga acgaatttct tttggaagtt ctgtacccga tggccaagca 139800 atgcacttgt caccgaatgg atttccttca cgtaatggaa gaaccattac tttatttcca 139860 tccaaaattg gagctacacc cagaccacta acagctcgac gataagttag cacaccgcga 139920 atatggaacg ggcatttaaa tcctggccaa cctttatcat catatttcgc tatatcgttc 139980 gcagttttta cttcagcaat aactttatag tcaagttgac gatattcttt ctcgaagttc 140040 ttgtagtatt cttggacaga ctcttcacct tcctgaagaa tacgacgaat actttcttcg 140100 agagcttctt gcactgcttt tggtgttgaa ctctgctgag tttccatacc catgattttt 140160 agatgcggtt cagcaaatcg tttatcttcc atatcataaa cgttcagagc ataacgcttt 140220 ttcgctttcc aaaatccacc aacgcccttt gaaccaagtg gagggcaaga aatagcttca 140280 cggtccatat gcatcagatg ctcgcggtta ttcatataat cacataactc acgatatgca 140340 acatcaatca taggttccat ctttttctta ccgaactgat tcatgaattc aactaaatcg 140400 ttctgctctt tgaatcggtc aagaccaact ttttcaataa ctttatctac acaaacatat 140460 accgaatcag tatcacctgc tgcgataaaa tcttcaccat tagttccgca tactttattc 140520 agatattcat tgattttacg agcaatccac tgaataccga cttggccaaa aattgtgata 140580 gcagtagcat ttcgcaaatc atagtaacgg aaatgaatat taccaagagc accataaaga 140640 ctgttaatga gaattttacg gttcagctga tttgtgttag caagtgtagc agctttttca 140700 cattcctcaa tcagactatt gagaacagat tcagtataat tcgacagttc atttaagaaa 140760 tcatcactga acttaacata tcgttcaact tctggtttag ttgaacaaga ccctgcgcct 140820 ttcataataa tctttttaat agcttcggca ttcatttctt cagcgaacat tttctttttc 140880 cagtctttac gctggaaaaa tactttagcg atttcctttg gaatgatacc ttcttgatgc 140940 ttatcataca tccatccatt cggagaacaa gaatattcat cactcggttt aggagctgtt 141000 cctgcaatat attcatgaat tggatgaact ttaaactgcc cacgaatagt ctcaggacta 141060 atgttaacct gacgaataat gctaggatac agagacgtca agtcaaaact cataatatat 141120 cgacgagcaa ttggtttagg ttcaaacaca aatgcacccg gaaaactctg tttaacgtgc 141180 gaaccttgtt gaggaataac cttatgttca cctttcaatg agttaaaaat aatagcatcc 141240 caagttttaa taggactcat tacaccagaa aaaggcattt tagcataata agacatactt 141300 aaaactagat cgataaaccc gcgaatttta tcaattgctt gaactgattc tacgtcaatg 141360 atgttataac taatgtatcg ttgatgatta gtttcacgaa gtttattaat aggaccatcg 141420 tacggtaatt tacctttttt ggtttcatgt tgagcaactg attccaaaga gaatgacggc 141480 aaattagtaa atgcgaattt cttgtacaaa tctaaataat caagaataga tacgccatca 141540 atagaataaa tttctttgct accgtacaca ttttgaatta gtttagattt tacccgaccg 141600 attggagaga aacgtttcat actgcgttca ccgagaacca ttttaacgcg attcatgata 141660 tatggaacgt caaacccctc aatattccaa ccagtaaaaa tagcaggtcg tttctgttcc 141720 cagagattga tatattccat gagcatatca cgctcattat cgaatggcat ataaattact 141780 cggtcaagaa tttcttgagg aacttcatca ccaccttcac agtcaagctt agcagctaac 141840 tttgcatccc attttgatac tgaaccgtac attgaattca aaaggtcgaa aacataaaaa 141900 cgatcgtcaa ttgaatcata atgagtgata gcatcaattt catattcagc tttcattggg 141960 tcaggaaatt tatcaccagt aacctcaatg tcacagttag ctacacgaac aaattttcgg 142020 tcataaacaa tttctgaacc atacgtatca ctgatataag cgagtttaaa atcgttcata 142080 ccaagagctt cgagaccgat gtcttccatt cgcttcatcc aatctcgagc atctttcatt 142140 gatggaaatt tttgaggagc acagttttta ccatagatgt ctttgtattt tgactcttcc 142200 ttacaatgcc taaacatagt cggaagatat tctacttcac gagtatgttc ctttccgttt 142260 tcatcaatat aacgctcaac aatgttattt ccgactgttt caatagagat ataaaattct 142320 ttcatagata ttccttagtt tatagcccga gttattaggc tcttgatata ttatactcca 142380 attaaggggc cgaagcccct tgcttaatta ccaatcgtat atttaggaac gagtttccat 142440 tcatgttttt gtttaaaaga aataactcgg aagttattag ttaaatcttt cataaaagtt 142500 ctttgaccag ggacgatttc aatcagtccc caatcttcta atagccatgc aatcgaatca 142560 cgacgaactt catcttcttc tgtcatttca acttggcgac catccatacg aagcatttct 142620 ttaaaatgaa cgatatagta tagtcctttt ttctgaagaa tatgacagga ctgatacaga 142680 actttatctt tattattagc aattcccata cgagtcaaag tttcttttac tttcagaaaa 142740 tcttcaggtt ttttaagagt aatttcaatc attttaccat tccaatgcta gttttttgag 142800 ttgtttctgt tcttttacgt tcttagtcac ttctttcaaa aaatcatccg tgactaaacc 142860 ttttagttct tttaatacta aaggaagttt tccattttta gtaagaattg atttatagtt 142920 aattgcatca tttgtattaa cttgataccg tttagcaagt aacttaataa tcaatacttc 142980 agtggaatct tcaaccagtt ttgcccattt accatatctt ttaccacgag gaactgcagc 143040 catcagataa ttaaaatgag cttcatcact taaacctgat ccaattaaat tcatagcata 143100 tacagctggc atgcattcag gaaattgtga taatgcattc tcaaccatgt attttgaata 143160 atctttttga gcaatagagc atttagtttt attattaata gctccaatta tttcaaaaaa 143220 ttcattttca gctttttcct tgaaagaatc agcagcggat tggacagctg tccaatcttt 143280 tgaataccaa gcaacttgat gctcgtttaa ttgaatatca tcttcaaata agctcatatc 143340 acttccactg catttcacat gctaactgaa tgaaaagata tgctaaatgt aattcagtat 143400 tagccgcaat tccatgatac tggttatttt caccaacaat ttcatacata cgaataatac 143460 tttgcggagt tacgcgtgta tagatttctt cggcaagttt acctacgaac cacgaataat 143520 cagctgcata ttttggtgct aaagctctga gctgtttaac atctttattt ttgagagact 143580 caagaacatc atcaatagca ccacgatcgt tagtaaccag tgataaaata ccagcatcca 143640 aaacaccttt agatgaataa ctatcgagct cgccaatagt tttacgaaaa tcaggaaaat 143700 tctttttaac caaagctgct acaactttca tatcagctat agcaattcct tcacgcttgc 143760 agatttcagt caatcgacga atcatctgct tcatcatttc aattttatct tcatcggtcg 143820 gttgaccgaa tgtaataact cggcagcgtg actgaagtgg tttaataata ccatcaatat 143880 tgttagcagt aataataata ctacagtttg aactataagc ttccataaag gaacgaagat 143940 gtcgctgaga ctctgctaac cctgaacggt caaattcatc aataacgatt actttttgac 144000 gaccatcaaa tgaagctgca ctagcaaaat tggccaaagg accgcgaacg aaatcaattt 144060 tacaatctga tccattcaca aacatcatat cagcatttac atcatgacac aatgcttttg 144120 ctacagttgt tttacctgtt cctggagaag gagaatgaag aataatatgt ggaatcttac 144180 ctttacttgt aatagattta aaggtttctt tatcaaaggc gggaagaata cattcatcga 144240 tagtagatgg acgatatttc tgttcaagaa tgtgttcttt ttcatttact gtaatcataa 144300 tttcctcatt caagttttag tgtaaattat aaagggccga agccctttat taaaaatcgt 144360 gggtagaatc agcttcaaga gctaccacat aattcgcgtg ttcaccttca aatttagcag 144420 caccttgttt accttttgcc cagagcagaa gtttataatt tcctggttgc attttcatat 144480 ttgccatatt gataatgaaa ttaaatgtat tttcaccgtc ataatcacca agagtcaaag 144540 aatatttaac acgggtcaga gcagaatctt ctactttatt aaaaccgtta attacgattt 144600 taccttcttt taccgtgata gcaattgtat caatttgcag accacgagat acacgcaaca 144660 gttgttgaag gtcttcagct ttaatttcag taacaacaga tgctaccggg aatggaattg 144720 gtttattagg agcaactact gtactcggat cggctgctgg ccaaaaaatt gttgagcgag 144780 catcagcaat tttaatatta ccatcttctg actgggaaat ttctgcatca tcattaacta 144840 aagacagaat accgagaaaa ccgttcaaat cgtaaattgc tacatcaaaa tcaataacgt 144900 cagaaatatt tgcttccgca taagttgtac cattaactgc gcgagtcata ataaattgac 144960 cggatttaag cataataccg gagttaatag tagcgaaatt tttcaaaata ttcagtgtat 145020 ctttagacag tttcatgtaa tttccttcaa ttcaaatgag atttaatttt ataactaatt 145080 taataaagca attaacgatt aaaatcagcc gcaattgttt ccgcaataat ttgagcagca 145140 acaattagac gttcatctgc attaccgcaa taatcatctt caaggcgttc accacatgaa 145200 gtcataataa atttagcacc agcgtttaga gattctgtag tatgtttgcg cattagttca 145260 atccatttat tacttacttc acgatcgata gcttcataat acgcatgacg agcaggtgca 145320 gatttaattt tgttctgaat aacttccatt gcgttatcag aaagagacaa aacccatgct 145380 cgacgaattt tattttggtt ttgtggattt gattcagaac gcacgtgttt tggctgaata 145440 tcttttacat caacagtata attcacagta attttagtca taatacacct ttagtcataa 145500 taatcagtaa cagtccaagc ttcatttcta ttggacatta tttttgtata ttctgattta 145560 aatgcattcc taagcataga ttcagtaact atatgctctt cgttagaaaa attatttctc 145620 agaatatatc gttttatttc aggaatagtt aatagatgct gtccagttga atattccatg 145680 tttttcctcc atagagatta tactctaata aattaaagca taatctctta taaattaaac 145740 cattacagta aatcgaccga ctttcttcat ttgaagatgc tgaccatatt cttgcgggtc 145800 atggtcttta tgcgaaatta taaaaacatt agtgtttttc attgaattta taatattagc 145860 tacaccttta ataccttcgg catcaaatga cccatcaaac acttcatcaa gaattaatgt 145920 actaatacta acaccagata cgatagaagc aatatcacgc caagtaaata aaagagcaat 145980 atcgattcgt gccttttcac cttcactaaa tgaagcataa ctaaaatctt cacgaccacg 146040 ggatttaatt gtctcattaa attcttcatc taatgtaaac acataatccg cttccattat 146100 tttaagataa tggttaatct gcttattaaa taatggaatg tactttttaa taatagcacc 146160 tttaatacca gaatctttga gcatatcagt caaaattcct cggtggtatt tttccattac 146220 taaattagtt tttgtcttaa caattttatc aagttcttct tgaagcagtg ctatttcatc 146280 agcatggtca ataaactcag aagatgcttt ttctatagcc gctttaacct ttttagcttt 146340 atctactgct gcgatcagag attgcttttt attgcgaata tcatttgcca acgactgctg 146400 ggttttaata ttatctcggt attcatcaac aagaactttt aaattatcac ggtgtgttga 146460 aagctgttca aacgaatgcg tacattcaga aactttatct ttaattttag aaacaacttt 146520 atcaccggaa cttaattgtg acaaacaggt tggacataat ccaccttcgt gatacatatt 146580 aatgacttta ttatacgagt caatttttga tttaatcaaa actgcttctt gaccgatttt 146640 attaaatgca tcagtagggt cttcatccaa aacaatatta actaatcttt cattagcttc 146700 ttctatttcc gattttagcg ttctagcttc ttttgccaaa tcatcataca tattttgaag 146760 acgagtaaga ttgtcaccag acaatttttt ctggcgttca acattatcat tatatatttt 146820 aatttgttgg ataatactat cttttttaac atcaagcact tggttttgtg aatttaattc 146880 acgtattagt gctttattaa gcttatccat ttcagctaat gttcctacct cgagcaggtc 146940 ttccacaagc tttcttcgcg caggggtcga caaacccatg aaaggggtat accctgctgt 147000 accaaggaca acaatctgct tgaaactggc atatgacatt ccgataagct gttcaaattc 147060 tgcttggaaa tctttactgc tggcagattc attaagacgt gtaccgttaa cggtgatttc 147120 gaaaacgttt ggtttttgtc ctcttttgat ataatacttt ttctcatcat attccatcca 147180 cagttcaact aaaagttctt tcttatttgt gctgtttatt aattgacctt tctttacatc 147240 gcgaaatggc ttgccaaaaa gcccaaatgt gatggcttct aacatagtag acttaccacc 147300 gccatttcgt ccagtaataa gagttttttg aaccttatct aattgaatgt caataggatt 147360 tccacctact gacattatat tttgatacct aactcggttt agtttaaaat tcttcacaaa 147420 agattccttt taatgtatct tttagaccat tctatcatat catcataatc taaaaagtat 147480 tcatcaaatt cagccgtgca aacaacgcct tgtgctgctt ttgatgtgat ataaattatt 147540 ccaacatatc tagaatcttc ttcggtgtaa tcaatatttg ctatgaattc atcattaatg 147600 tcaaatgtcg aaaacttcac agtatgcatc cttaatacaa gatacagcca tatttcgtaa 147660 tgatttaggt gtgtcattat ctaaaatgtt gaagttaaaa gatacagccc agtcagtgca 147720 gactgtaacc tttttaatac aattatcttc aacttctagc ggttcaaacc agtattcaat 147780 aatttcttta tgcccaatat catcttttac ttcgcattca aaatgctgac tcatcataac 147840 atttttaaat tcatcaaaag tcattgtgtt gcctctacat atagctgatt tgcatattga 147900 ataagtgctt cacggtcaga atcagtgatg tctggaattg cattaatata ctcttccatt 147960 aatgtctgaa gcgattgaac ttcaacttct tcactgtcat ctgactcgac agagttatca 148020 atctttgaca caactcgtaa tgaatgcaca actttttcta gttcagattc gaacttcgtc 148080 agatttttgt ctacttcagt tactataaca cgtactgata gatttgtaaa atctttatag 148140 tcaatttttc ctttaaatgg ataatgaatt ctacgatgcc aggtagtatt gtttggaata 148200 aattccattc gttctgtttc tgtatcaaac atccagaacc cacgagggtc attctcgtca 148260 ccggcagtta gtgtccatgg tgtcccaata tatctgacgt tagcagcctc agagatagta 148320 tggaagtgac cagaccacac ctctttataa gtcttaagga aatcgggttc aagaccatga 148380 gatttcattc ctttataaaa ataaaatcca ttcagttccc agtgaccaac acaaaaagaa 148440 gcagatgaag ttttgatgtg ctcaagaatt tcaccagtat tttcttcgca catccaagga 148500 attaaatcaa tcaaacatcc gtcaaaatct actgtagtag gcttatcata tactttaaca 148560 ttaggatatt tagccaaaag ctcagtagag gcatttggat gcattacatt tttgtagtgg 148620 agatcgtgat ttcctacaat agtatgtaat gtgattccag cgtcatcaag catttgaact 148680 atttcacggg caaactccat agttttatgt gtgattgctt ttcgcacatc aaaaatatca 148740 ccatattgaa tccatacagt aattccattt ttcttagaat attctattgc ttgtttaatt 148800 ccatcaattt gaataccgcg aatccactca tcatcagctt taacgcctaa atgccaatca 148860 cctaaattta aaattttcat atatcaagaa ccgtcattga aatgcaaaat aaaattattg 148920 aaataaatcc atctggagtg ctaaagaacc caatccaaca tgctctagcg aatagataaa 148980 atgcaagaaa aagtatcaca tatccaagaa atatcattat atcaaactct gtataaagct 149040 aaagggccga agccctttat tttgtaataa tgtcaaactg ttctttaaag cagaagcttg 149100 aatcttgatg ctgatacaaa aattcatatg ctttttctcg ctcacggtca taaagagctc 149160 ggtcagatga cagttcttta atacgctcga atgttgattc catgtcattt tcatcaaacc 149220 aaatgatacc gctatcatgt gaggtcaaag gagtattatc aacacggaat tttaaattat 149280 cacctgttga tttccagaaa acaggaattg taccgcaagc acctaattca agatgagtat 149340 attcgagtga gcgttgtaag tatttctggt taagtttact caactgatat ccaaagccag 149400 atttactcat tcgttcaagc atttcactat taatataaca atctaggatt tgtgccggtt 149460 gattcggcgt gagattcatt ttatcaatct cacgattacc ataatattca tacggaatac 149520 ctttttcctt aattgcaata aaagcagggg aacgttcaag accttccatt acagtggatt 149580 taccagcagg ttttaagaat ttttcgtgaa aatcaaacat ctgataaaaa cctttccatg 149640 tagtcgtacg accaatccaa cggttgatgt tcatgttaat ttcagaaaca tctttccaat 149700 aagttgaccg aaccttcgca atatccatag gaggctgaaa attatatact gttggtgctt 149760 cttcaatatc atcaaacaga gaaacagttt ctggatacca ttctttcatc agaactttat 149820 taaaatcgcc attatcagaa tgactaaaaa taacatcagc tcgacgaaca gtttcttcta 149880 atcccaaatt tcgacgcaaa gaaagaacag aatgatcatg ctgataaact acaacacgaa 149940 tagaaggttt aatattatct aaaagttttt tatagttatt aatcgtggct tcttgaacgg 150000 aagtagcagg aacagaatta ataattagaa tatcacaatc attaatcagt ttaagtgctt 150060 tatcgtattc tttagctaaa ataactggaa ttgaaaatga tttgtggtca tgagaacttg 150120 tacgagtaaa tgatttatct ttagcataaa ccaaagttac ttcatgacca tttttaataa 150180 accaatcacg ctgctcaaga gaaaatttag ttacaccaca accttcaaga ccccgagcca 150240 gaaaaatgca tactttcatt taatatcctc attgttttgg tttattttac caaaaaattt 150300 ataaagcaat ataggagccg aagctcctat ccgcataata cgcccataca aaggctcgtt 150360 agagcttcta aatttttata cgcttatatg ttatagttcc ttctgcttta gctttatcat 150420 gagactcttt aaagcgtctc atcatttcta ctttagagga acgaatttta ttataatcta 150480 tttcagaagt ctggtgttca tctttcataa ctgccaccat tttttgactt gataagaatc 150540 aacccacact ttcatattag ggtctgctct tacaatagga ggattaactt ctttaattga 150600 actatcgtgg tattcttttt cagaaatttt cacgcaaaga tgaccgttca aagattcagt 150660 aaatcctgca ttaattttaa gacgcttgaa ttttacgtgt gtaagcatca atcatatcct 150720 caatctgcga tctagtagtc ttccaaagaa tactgatgag ttcatcgtta tatggctgtt 150780 ttagaatatc ccgacttttc ttgatagcat actcgtattg agcaaaatta ttattttcag 150840 ccgcaatctg agcgtgctta taaagacgat tcagttcgcg tttgttttta gacaataact 150900 tatttgcttt tctttctgct tcaagacggt tcttttcttc aatagaagaa ataagctttt 150960 ccacttcatc attaatttcg ggtttatcag tcatattatt tctctaatat aaaataaaaa 151020 tcatcatctg ttaaatgata ccgatagttt aattctacac cattagattt aaaagcggta 151080 tcatacggat tttctggatc aatatcaatg tcaagagcta aaacttccct gagatacatt 151140 ttaagtaaat agggaatagc ttcaacttca ggtatttctt ccaagaatcc ggagaggtta 151200 atcgttagcc tcatataaaa aatccaaact aggagaatcg tctacaacac ttttcttttc 151260 agcccccggt gttctatagg ttgattcttc gtaatgcgtc attttatcgt agatgtcttg 151320 aataaaagtt tcatctacta acgcaaccat atcgtcgtca cggctgtcat agacattgtg 151380 aacgaagtaa ctatatttct ttgcaacttc cttacgttct tttttaatac gttggacgaa 151440 tgcattaaaa caagcttgag ttatatacgc atgtgggttt ttatatttcg tttcatcaaa 151500 attatgaagc cccttaatag aagcttctat accatctgca atcatttctt gtttccaaga 151560 ctgggtgtat cctgaaaagt tgaaacgttt agataagcct tctgcaataa gcataatggc 151620 taatccgata gtatcattct gacgaactac tttatttggg tctttattat ttgctaattc 151680 tgttttccaa tcaataatag cttgtaaaag ctctttattg tttacgtaat tatatttagg 151740 cttagtttct gacattttca cctcttagct caattcatag atctattata tcataatatt 151800 tgaagatcta tcttaaagca tagaggatat cagttatcta agtaaacagt atgcttggaa 151860 tactttctcc atcatctttt taaattcatg aatatctata taatgactag ttaaatcagc 151920 atgatataaa aagtctaaaa acttttcatg tgtgctaaca tattcacttt catttaattc 151980 agaaacatga ctttcccaat atccaacacc agtcttattt gggaaaaatg aaattttcat 152040 gcattggtca acatagaaaa tgccataatt ttcaatagta atagaaatat taataaattt 152100 catacattca tcaacttagc cgcttcaaga gctgcatcta gtgaatcaaa ttggtcaaca 152160 tattcaatca attcgccgta attagcatat aaccaccatt ggctaaattc atactcaagg 152220 atgaatccgt ttccttcaat ttgagttaaa ccaatgccat ttgtatttac ttcatatcca 152280 gcaagacgca aatcgttaat aagagcttcg ttcataatta taccttagta attttcaggt 152340 ctgcaaattt tttcttgcgt tgatttttca tgcgacgaat agttttatcg gaaatttcat 152400 gcttttgata agctttagat tctacaccaa aagctttaac atcaaattct gacaagatat 152460 attgaaccaa caattcacgg acagtattgc gtccaatctt ctgatcattc tgtttcatca 152520 tctgatgaag ctctttttcc catttatcca aaatttgagg agttacaata tcgccttttt 152580 ctagcaaaga aactacttta tcatatgcgt aagaattaat gacgttttta atttgaatag 152640 tcatacatta tcctcaatta cgttaaaatt ttattatcca aaaagggccg aagcccttag 152700 ctaaactttt tggcaccctt ccagccttcg tacatcattg cgactgacaa tgacaaagct 152760 ccttcacatg ctgcatactt attattccag aaccaattta gaaaaacttc atcctcaata 152820 ccattgtgtt tcatgttctg gaaaaatttg gcgcgttctt cagcaattcg ctgcgataat 152880 ttagattcag gattcattta aatttcccaa ttaccatttt catcaataaa tttaatccag 152940 tcattgactg accacttggt cgtatcgcct tttggagtaa catttaaagt atataacccc 153000 tgcttaaaaa gcattcgttt gatattcata ttttcctcag ctgtaacgat agcactcgtt 153060 tgatttacgt ttagcaactc gttgagaaat attataatca aaatcatcgt caatgtaaac 153120 tgattttttc aactttctta cttcaccgcg taattgacga tttaactcat ctttaacttc 153180 tgaatcaata cctttcattc tacgccattt atctgagcga aaaatgtttt caaccatatc 153240 tttatgactt accccatcag gagctttacg ctttccgaaa tagtcataat cacgcacttt 153300 taagtcttta cgacgatacg ttttacccat agagtttaat ttccttagca actgaactaa 153360 atacagcacg gtcacaaatc atgtgtttat gtaacttaag tataagataa taaacatcat 153420 aaccatttac gtaagtaacg cgaacagcat taccattaat aagataatac tgtccctttt 153480 taatttcttt atcaatcata accatatcaa ttcctcaaag gcaattcatg tgttaataat 153540 accacggttt gaacttgttg taaacaactt tgtgaaaata ttttagggaa tgataagaaa 153600 ggaacgatag cttagaatgg taatatacag aatgtaagaa agaaaggccc agagggccta 153660 tcttagtctt ctatgatatc tctatcatat ccaagtgaaa tgagggtttc tttgaagtgt 153720 ttaatgttct tttgtctaga atcattaatg aaaatgactg gataacgaat gttaagagat 153780 gtaaatccag cgcgtttagc aagagataca atcagtggac gatcatactc aatcttacca 153840 ttatttgtaa gaactttata gaaagtaaaa ggagcattga gctcctttag aagttttgta 153900 actgattgac atccaggaca acgacctact tcatctggaa ttccatagac ttcaatctta 153960 ttctttaagt tcgagttttg ttccacgaga aataattcct tggtaagccc aataaggagg 154020 attaacagaa tcctcaccag agttttcttc aggaaaataa acctggataa cgaagccgga 154080 ttcatcaaag gtaaaataaa ccgtaggcag ttcacctaac aaatcggcac gagcgttgat 154140 ttcttcgagg tcttgttcac gtccagccca gaagcttggg ttcagactac attcatagaa 154200 ataatagtca ttaccgaaca tatcaaaacc attccaactc tctactacat accgctcaaa 154260 actaatcata attaatcctt tttatcaaga accgcattca gcttgttagt aattttatcc 154320 agacgctcat tgaactcact agaagataaa cctttttctg gagaaattaa gctaatcacg 154380 aaaaatatag caataaaagg aataaggaaa atagctccaa ctgccataaa cagaaagaat 154440 gttacagttg taagaaaatc agctaaacct ttacgaaatt tatacatatt ttatccttaa 154500 ttaattaacc aagcattgat aagtactaaa ctatactgcg aataaaattc tggaccaaaa 154560 tgaaaaatca tatcatttat agtatccata atgtaattca atttaatcat gtttccacac 154620 cccatcggta tttgaccaaa gtcgctgatt atctgatcct cgccacaact ttttagtcgg 154680 aagatttttc tcatacttcc catcaataat aacatcaaca tatttaagca tttctagttg 154740 tttaatatct tcaaacttat atcctgtcca caaccaaatg cttttattgg gataaagatt 154800 tttaatagtt tgaaccacag agtgaatcac gtctctgtta tcaggataaa gagggtcacc 154860 tccagttata gtcaatcctt ctatataatc attattcaaa cattcaatta attgctctag 154920 tgtttcacca gtgaatggaa taccatttct agcattccat gttgatttat tataacaccc 154980 ttcgcattta tgcaaacatc cagtaacaaa aagaacggtc ctgcacccag gaccattaac 155040 aaaatcgcaa ggataaaatc tatcataatt cattggtgtt taaccctatg catgatttct 155100 ttatttttac cgagattaaa tccgcgttcg ttcgggtttc caagatatcc gcatgttctt 155160 cttatggtgt tcatcttttt aggatcagtt tctccacaaa tagaacaaac aaatccgttt 155220 tcagtaggag tcatttcatg ggtacttcca catgtaaaac atttatctac tggcatatta 155280 acaccaaaat aatctaaatg ctgtgcagca taatcccata cggcctcaag accttttaag 155340 ttatttttca tatcaggaag ttcaacataa gaaatgtgac cacctgtcgc aatgaaatga 155400 tatggcgctt cacgagaaat cttttcaaac ggagtaatat tttcttctac tgaaacatgg 155460 aaactattag tgtaccaacc tttatcggta acatctttta cgcttccata tttttctgta 155520 tcaagtttac agaagcgata acaaaggttt tcagcaggag tcgaatataa actaaaagca 155580 aatccagttc tttcagtcca ctgtttaaga tgggcattca ttttagttaa aatttcctgt 155640 ccaatatcac gaccgacaag aatattcaat tcatgaatac caatgtatcc tagggacact 155700 gaacttctac cgtttttaaa taactcaatt atgtcgtcat caggtttaag acgaacccca 155760 aatgcacctt cttggtaaag aataggagca acagtagctt taactccttt taaggaacta 155820 attctacaca tcaaagcttc aaaacacaaa tccattcgtt cattgaacaa ttcaacaaat 155880 ttctgttcat tgaactgtgt tccaatataa gaatctaatg cgatacgagg aagattcagt 155940 gttacaacac caagattatt acgtccatca agaatttcat taccagtcga atctttccat 156000 acactcaaga aactacggca acccattgga gaaacaggaa cagatgaacc agtgatagct 156060 ttattattct tagctgaaat aatatcagga tacatccttt tgcttgcgca ctctagagca 156120 agctgcttaa tatcatagtt cggatcgtct ttgtaaagat taacaccttc ttcaacaaac 156180 ataacaagtt tagggaaaat aggagttatc ccgtcacgac caagaccttt aatacgattt 156240 ttcagaattg ctttctgaat cattcgttca gtccagtcag ttcccgtacc aaatgtaatt 156300 gttacaaaag gcgtttgtcc gtttgaactg aataacgtgt tcacttcata ctcatacgcc 156360 tggaaagcat cgtatacgtc tttttctgtt ttagattggg cataattcaa cgcatcagcg 156420 atttgccatt tttctgcatc ctcaatatgt tttgcatagg tgcgtttaac ataaggagaa 156480 agtactttat ctacattcgc aaaagtcgtt ccgccatatt gatgggaagc aacctgcgca 156540 gtaatttgtg ccataattgc agtagcaaca ccgattgatt taggagtttc aatctgtgca 156600 ttaccaagct taaatccgtt ctcaagcatt ccttttaaat ctactaaaca gcaattagta 156660 aatggaagag caggggaata atcaatatcg tgcacgtgaa taattccgct ttcatgcgct 156720 ttcataataa aagacgggac catatttttg gcaatgtgtt tagacacaat accagccata 156780 aggtcccgtt gagttggaaa aacacgagaa tctttattag cattctcgtt taaaaggtct 156840 ttattagttt tatgaatcaa tccttcaatt tctttttcaa ttgtcatttt aaactctttc 156900 taagctgctt cttaaatgaa gctattaatt gtgttttggt gtcagattca ttatattcaa 156960 atcctctttg aagcatctca gccatcattt cctcttttcc taaacgagaa aattcctttg 157020 atttatctcc aacgaagtta gggtgaatat tattttgggt gtaatcggat tttaaataag 157080 taagtaaatt ttctaaccat tcaagataat caacaccttg tccctttaag ccagaacgat 157140 taaatttgtg cttcatttga ccttctgcgg cattgcagag attacaaagc aatccacgta 157200 cctttcctgc ttttggtcca tttaattcat ggtcatggtc aaggtgatta gcttgaacgt 157260 caggatttag ttctcgttgg caaattaagc atttaccatt ttgtgcatca taaaatttct 157320 gtttttcttc tttatataat ttgccagtca ataacataat aaaaccctta ccttgaatag 157380 ataagggtat ttattatttt caagtattgt aaaacattcg atgcaatcgc ttatattgtc 157440 gaatcatctt tttagtagga cgagaataag ttcctacaca agtggtcata ttagggtcag 157500 taggacttcc tttaataaaa agtttccaga ctttaccgcc atttaacttt tcagtataaa 157560 ccaattcggt tttcattaaa atgccttgtc agaaaaagaa ttttgagttt tttcaagtat 157620 tgtaaaacat ttgattcaat cgcttatatt gccgaatctt ttggtcagaa aaagaaattt 157680 gagtttcaag ccattcaatg tactctgcgg cagcttgcat taaatttcct tcataaccat 157740 cgttattttc ttgtgcagct aatttagcta atgcgtatga aatacgttca ccttgaaaag 157800 cggctttagg cttctgaaca tcttggctag ttctctctac aacttcctcg atttcaccat 157860 tttcaacaga ttcagtattc cacaaacacc aatacgtaat tggcttatca tagatgttaa 157920 taatctttcc gtcggaaagt tcaatttcaa taattccagt gtcaggctct atatcatctt 157980 cacattcttt tgcaagttca cgaactttaa agacagtacc tgcactaagt tccggccagt 158040 aattacatag ccctgtatca acacgattaa ttctaaacca cttatctact gtaatcatgt 158100 cccatctcca tatcaattat gtcatttatt gtaggttcat tatatactgt ttcttcatca 158160 gtgtaaaccg gttcttccgg ctctggctct acagtttccc atctatccgc ccaccaaggt 158220 ttaaccccga agcttattaa gttcttcata atcaatccag gattctaatc ctgatggcaa 158280 atcagattca atttcccaaa gaagttcttc aattttatga agacgatcta attcttcagc 158340 tggaatagta accattgatg gagttcttga tacactaata tcgtaaatca tatttacccc 158400 agtttgacca tgcaatcgcc gtatttccac ttagaaatag acttttcgcc attagaataa 158460 taaacttcga gtttagcacg gttattttta atttgaataa tctttgctgt catcaaagtt 158520 ccatatccat agtaaactgc aacttcatca cctacatata ccgcgcttcc acgataatca 158580 tggatataat cagttccttc gagcatcatt taaagtattc ccgcaattgg tcaaatccac 158640 caatatgact tccatcagga gcaaatacct gaggcattgt caagccgatt tgagtatcac 158700 gacctagttt agtcagaagc tcagcaattt tctcatcatc aaaaacacct ttttccggca 158760 taatgttgat aaattcaaac ggctgtttct tcacagtcaa gagacgtttt gcattatcgc 158820 aatacacgca tttgtggatg ttgctatcat aaccatatac tttaaacata ttattcctta 158880 attcctagta cttgtttaaa agtctcgtcg taatcaagac tttggcccgt ttgttcttta 158940 tgtttgtata taatatcact tacttctgat agcatatttt tatatgaacg agttaaagct 159000 gatttaagca cgctgtatct atcaggaaat ttaccgtgtt cattataata agctattgct 159060 aattcacgga ctgccttttc agcagtctcc atatattctt tacgcttggt cattttcttc 159120 tcggtcaaat cggtgtttac aatgacgaca tttataacga agattactag tctgccaatg 159180 gaccaattgc acctgttcag ttccacattc agggcaatta ggaacgtttt tagaagccct 159240 ttcacgacgt tcaaccatga ccattacaga atcccaatta acaggagggc tataatcatc 159300 acaaccatga atctttccac gcatttccag atcgtcttct tcaccagcca taataatttt 159360 aattagacta gaattacttg aagctgcaat gtcttctaat agacgctttt tcatttcaat 159420 acctcaatag cattgcgtaa accatttgct tttgcattaa gagcttttaa caatttggtg 159480 tgttctgcaa tttgggcttc aacttcaatc aaacgagcat tgagatattc gcgttcttca 159540 ctcagattat cagccttttc tgctttaggt tcttttacaa cttgcttata tgtattaggg 159600 ttcttcagtt taattagaat gcgtgaactg tacagcattg aaccattatc ttcggtttcg 159660 tcatacattt ccactacgtc catcatctcc accatcgtgc agagtttata agacaacgaa 159720 cgaataattt tgttgtgctt attaatttct ctagctgtca tggtgccgag attacgtgag 159780 taataataag gaacctggat attaattaat actgatgaac cacctggctt gtgtgttact 159840 tcatcagcaa taacccaatc cttaacatga actgtatttg tacggtcatc gcccgcggta 159900 aatagtttac gagcatgctt aaaaagcata ttcacttggt cattgaattg acaagcgaat 159960 ttatcagcaa atttagtttc gggaatggta gataaccaat cagccaaatg ggtcttttta 160020 acatcgttaa caatagtaaa ttcaaccaaa tcggttatag atgtctcaga tttaatgaag 160080 ctcggcttca taaagttttt aatgttatca ctagctacag tagaagataa cagacgagaa 160140 cgtttaaacc attgaagcaa attgcctaac gaatgtgaat acgcattttg tgtatcttta 160200 caaatatggt tttcccatcc aatatagtct aaaaaatcac gaagaatatt attgattact 160260 gctctgtgtc ctatctgata attacgatgt ttagtaataa gactgtcaaa ataatcaata 160320 taatgtttac gagttttcat gttcttctca cttggttaat gatttatact ccgagccatc 160380 cttggcttta aattacttaa ttaactgtaa agcttgttcc agacgatcaa gacgattaac 160440 agattcttcc caaatccttt tagcctgctc atattctttc tgcgctttat tagaaatttc 160500 tagaacttct ttataagctt tttctagtgc aataacttct ggacgaattt ctatcggttc 160560 aggtgaatta tcaagacatt ccattagttc ctcaagggta gtttcttctt taggagtatt 160620 cacaatttca tcacattttt gttggtaaat ttctttatca gttagtgaat aagcacattt 160680 cacttcacga aggctaatta cgagtttata tccttcccaa ccgcatatat tcttaaaagg 160740 atatgtatga atattttcta ctgtttccat acaaagtaat gcggtctcta attgatgagt 160800 tatagtgcta gcaattgaga aaaatttatt aatattcttt tggttagttt ctggtgtaaa 160860 aaatctgtaa ttaataaaaa tagctacttt gtttttatca agctcatatt cttctgctat 160920 aatcatatca tcagctaagg gatgaattgt acgataatca ccataacata atttagaagc 160980 tgattttaga atttgcttcg taaaactcct aaattcacta acccaacgac gagtaaaaat 161040 attctcaggg tcttctttag tattaagatg ataagtatta acatcaccga accaattata 161100 tcctactaca tctttggttc gtttaatttc tttcccaaaa ttaccaagaa tatcccgatt 161160 aaccaaatat gaaagaagac gagactcttt aaaggttttc ttgataagat ctttatctac 161220 acggctagaa attttacgaa tttcatgaat aaatttagta gaagaaacaa tacttgcatc 161280 aacactattg agccattgat tgataataga aagaacgcta ttttggccaa acatcggtat 161340 agctttatca tcaataacgc tattgaatga tttgatatat tcgttacgag tcataataat 161400 ctcctcagta gaaagtaaaa acattatacc acatccttgt ggcaaagtaa actagttcag 161460 tgcatttagt gcattgttca gtttagaacg ttgctttgtc agattttgaa cccttgactg 161520 agcttgtttt aacacctttt cagcttctaa cacttcattg gtcgctttaa cgagttcatc 161580 atctactgcc ttaagagact tctcaatcgc gtcagcgtgc catttttcta caggtttaaa 161640 atttgaattt tcagtaggaa gaaaactcac tttattaagt ttacatgcat ctatattgct 161700 tgagctatac atccaaaatt taggatcgtt tgatgagtaa ttagatgaat ttaaggtatt 161760 ttgcacttcc tgctttttct cttgaacaat ttcatccttt ctcaaaaatt catatttaaa 161820 tgaaacgatc atatcaagtt catatgttgt tgtatgttcc caatttcgct caaaatgagg 161880 taaaatctta gattgaacag cagcaacaac atccatatac ttaaatgctt ctgtcagctg 161940 tgatttaaga cattcacaaa ttgaaagaga attttttgta ttaggtttaa agctaattcg 162000 tgcagttcta ttattttctt ttaatggtct tacttccatc tgaagagtat aaccatcaaa 162060 tttcaggttc tttaagttaa tgtcagaacc ttttaatcga ctcgcaattg ataaaatttg 162120 ttttaattgt ttacggaata gagcaataaa tctccattca atacgataat gatttggatt 162180 gaaaaatcca gatgataaat caaccttact ttggccaacg cctcgaacaa atagaggatt 162240 tttataatca atagttttac agaaatcggt gagctgttca cgagcagtca tttgtgtaat 162300 ataccccgct ttactaaaat gacgtaacca ttcactgcta ttcgtatact taaagcgatg 162360 aataacacga ttaactttat cagggtctaa attattttgg cacaaaaatg tcataacatc 162420 acgagtataa ctggcattac gaaccatatc ttcaatttga gaacgagttt tcatggtgtt 162480 ccttaagatt taagtaaatc aacaatttta attaattttt cacgttcaga tttagcttta 162540 ctactcaatc cagatagtct gaaaatttca tcatcatatt gctgaataga aatattcagc 162600 tcttcaatct gcttattaaa ataatcaatt tgttcagaat gtttttcgtt actacgaact 162660 gatacaggtt ttgtaggcaa tttagttgaa ctggattcat ccgggcgata aattaaaata 162720 caatttgaac caatagggca ttttgcacca gacacatatt ctaatgttcc ggcttctttt 162780 aaaacttcaa aagctaaaca gagatgatgc cccatattaa cataatctgt agagcgagct 162840 ctgacgtaat aatcatctcc acgagtgcta aatttaaagc atttaaggtc ttctgtatta 162900 ttggtcttaa aaatcatttg tttatctaga cctttagcta atcgagcacc taatgctaat 162960 aatcgtcgtt gattttccca caaatccgca atcatttggt cgaatgataa ttttggcatt 163020 agtcgaccat aaaggtcata tcctttatta taattacgaa ggatttcact cgcgttaatg 163080 cgagacaacg ctccaatttt attaagggct ttcatgatgc gattagataa aagcattcca 163140 gacccgtttg ttcgttgtaa atgtttttct aatccaaatc caatatcaac tttaaactta 163200 tctaaaattt cggcgtgaac atctttatcg ataacattta aatttagtac tgggttaaat 163260 ttatgaaaaa atttatctga ctcgtcgcgt tgaagtacag tccattcatt tgatttttta 163320 ttaactaaag atttaattac tgcattgaca ttattaattg ctactgacat attttcctca 163380 ctcaatttca attttactaa atatacagaa taagatagaa cagactatat aagcaccaca 163440 cacagattga actaatacca ttccaaagaa ccaaacaata ttatcaaaca atgtctgttt 163500 tacgtcaaaa ggacgtaaac ttacagtaat attatcacct ttttctattg aagaatacat 163560 ctctggggaa atatattcac taaatctata accgtctttg agttcatata cggcaataaa 163620 cgataaacta gacccctttc cttgagttcc tgtaagggta ttaactacag taacatcata 163680 atctttataa tgcatataat cattaattgc gtaataacca tatgcaacta ctacacataa 163740 acaacatatc aataaattca atcttttaat tatcaactgt ttcataataa tctcagttaa 163800 aagggcttag aaccattata ccatccttgg tataaagcgg ttatgcgagt accgtcttta 163860 accgttcttc aaatttccga agagtgttct ggcgttcagc tctttgcttt ttgtaagttt 163920 caatacgctc tgaaatgaga gcgtatcgtt catttactga ttctttcata aaatcaggaa 163980 tttcacgaga agctttaatc tcatcaaatt tatcaataac agcttgctct tcagcaatta 164040 agttatcata cattaaaata tctttcttga taaactcaat atcttcttga gttacacgag 164100 ataatttaga tgctttatcc tttttgtact gttcgttagt atcacgagac cagtgtaatg 164160 tacgattttt attcgtattc ttgtaaattt ctacaatacc gatctcatcg ataataacga 164220 tccaattcca acgggatttg taaatttgtc ctccatcaac agtgatttca cctccgattg 164280 agatgtcatt aaagaacttg ctttgtgctt ctgatttaaa tttaccatcg ttgtaattta 164340 ccaggttgaa aatatcttta gcgttcattt tgtgctcctc cgtagttgat agttgtatag 164400 taccacagag gaacggtctt gtaaaccact aaaagaaact tctttcacaa ttttttccac 164460 tgaaccatgc gctcactgct ttcttagtct caggagcagt gttatccata aaccattcaa 164520 aggcagcctt tttatgattc tggagggctt ctcgggcttt aatctgctca cggtctatta 164580 acactaacat atgagccttt cttgtcacca ggggcttctt atgatttttt gaatactccc 164640 aatcatttgt ccatcgcatc gttgttgcga attgaagtac agcttcttta atcttagttt 164700 cgtaaatttc acgagccttt gagtataaca tcattacctc catttaccag tttaattcta 164760 gtcatctttt taatggcagt ccatataatc tatttctgaa ctgccttttt gtcttagaag 164820 tcctcttatg aatttatttc agaagagtaa cctcagcgat ttcttgccaa ccgtttttgt 164880 cggtcataat aaagtcagca agataaagtg cagtacgcag tgaaacatta cgtaaacggt 164940 taacattgac tttcatccat gataatgctt tataagtttc ttcatcagaa agaccgcgct 165000 tttgcatcat gtcagttgaa agaataacat cttcaaccct gaccataatt tcttcattag 165060 tgtgaacacc caaatccaaa taaaccgagc gggacactaa tgcttgtaaa tgtggagcaa 165120 gtttagtacc acggtctaat tcgcggtcaa tgtcaacgtt tgtgataaaa acaatcgttc 165180 ctttaaattc aaactcacgc tcaatgcctt tttcttctaa gtaagaagac gcagtgctcc 165240 agcagacttt acgggtctct ccagtgtcca gagcggcttt tagaagatta agaatatcca 165300 tatcagagaa aacatccaca tcatcaatca aaaggacaga attctcttca cgattattcc 165360 aaagctgctc ataaagacca ataccagaga ttttaccatt aatgctttta tattcaatgt 165420 atccaatatc atttgcttta tttaaagctt tatctaaaga atacgtttta ccaatacctg 165480 ctgcgccaga gataattaat gaacgaatat ttccgttaat aataccattc gtcatcattc 165540 ccataacatt aaatctttta ttaatgcggg ttttcatatc ttcatatgat tctttaactt 165600 cttcaacttt tacaccatca tatgaaatat ctgatttgta aacccaaaca ccgcgacgtt 165660 taccgtcaat ttcaacaaaa actttaccat ctccttgtgc atctaccgga gcattatctg 165720 ggaaccattc tcctaagagc tcaaaagttc cagagatttc tttaccgaag tagataccct 165780 tattgatagt tacagttttc attttattct ccaatttcac atttgttttg atagggtaat 165840 agtatcacac tactacccta ctgtaaacaa tttattttaa tgtttgccaa atttttactg 165900 cttcgcgacg agatacttct acagctccaa gttctacagc tttttggcgt cgccgagcgt 165960 gtaagtcata atgtttaatg cgtttatctt gaaaccaaga acgtttcatt cctattgctt 166020 ctgccatttc gtgaagctct tcaatatctc catcagtgaa catatgacaa tttttagttg 166080 gatgaccgcg aagtttccat ccatgattca ttaaaacatc tacgtaaact gtcattgatt 166140 cttctccaaa taagtttcga taattttctg agcgagataa actgcattat cttcagttgc 166200 atcttctaag aaactttcaa aacactctga aatttcttct gtgtcaatca acttttttac 166260 ttcaattggt gtaattttca ttttgttttt ccgtttaagt gtttgttttg atagttgtat 166320 agtaccataa agctttatgc ttgtaaacca ctttgtgaaa aaatttttga aataaaaaag 166380 ggagcccgaa ggctccctat catttataat aacttcggtg gttttcaaga tagaccttct 166440 caaggaagtc atcccagaaa ctcatgtcta ctgttttagg cataccgttc ttagaagctt 166500 cagtagatgc tgcttctact tgatcgacca catcttccaa aaactcttga acggttttaa 166560 atggatgttt acccaacttc acgtcgagaa taaatggagc gtcttgaagt ggataaacca 166620 agtcaccagt tttgtaaatt tccaatagtt ggagtccacc acgacaagca tgactcagag 166680 ctttccagtc aatgccttca ttggcttcgg ccttacgagc gcgttcaccg tattcagcat 166740 ctaatttgtt cagtgactgc ttaagctcaa taagagaaag cgttgtctga tatttacgac 166800 ccaacactgt gtaaaacgtt tgtggacctg ttttctcatg attatggaac acccattcac 166860 agaattcatt ttttggaaga cgatgcttaa tatcttcaac tttagtgcgg cgctgcttaa 166920 tagaaccatc ttcttggtaa tcaacccatt gctcggggat ttgattaact actttcaata 166980 catcacgtaa tgcagccaaa cgagaaccct taacaccgta tttagaagct tgtttgcgga 167040 catatcctaa ataggatttc atgttagtcg tataaaaacg agaacggttg tcttgaataa 167100 acttccacac atcaggcaaa tcagatttaa ccactagttc aggtggagtg tgaagcatat 167160 ccaatgctac agtttcacca tctgctgcta atttaaagaa atacttaaga ctatacaatt 167220 cgtggtcaat atcatcttta gtgtttttag atgatgtgtt gttggtgttt ttactcatgt 167280 gctctttgac atttccgata agaatatcac gagcaggagg aacaaagatt tctttaaaat 167340 ctacatcaga ttctggggta gaagttccat aaagatgact accaaaataa cttttcatta 167400 ctgttttcat cattcagcct tatattcaat aacaggacac actttagctt tacgagcttt 167460 taaaaattcg acgataatcg atttcttggg ttgaatagga ggtaaacctt tatacgccct 167520 atcaatattt tctacgtgta aagcataatc ctttttccat ttataatctt tatatttttc 167580 acgcaaatgt gcaggaataa caaatgaacc gataataagt aaaacaacca aaagcgcaag 167640 tataaatgct gatggaataa gagtccataa actaccaaaa ataagccatt tctgtatgat 167700 ttctgcacag atgatagtta gacctacgag tatagtacat ccgaaaaaag aaacgaaaaa 167760 tgtaggaatg gcaatagacc aaaaatatgc gcatagtgtc ttaggtcgtt gccattcatc 167820 gttaaacaat ttgaataatt tatagtgcca agagttttca ttaataatca taattatcct 167880 ttcattgaag gtgtaacagt tgttaaatac ttaatcatag cttcagcttc tgattttgat 167940 aatgaaattt ctccattgtt ttgacgaata gaaataaaat ccggatgacg gtcaccaccg 168000 gcttttaaaa cacacatata agtatcagtt tcatcttcaa tatttgaaat gattgaagca 168060 gttccacacg aatgtggttt ttgataaatc aatacagctt ttcttccacc atttgactgt 168120 tcataaactt ttaatacatc aaacaaatca cttcttttat caatagctaa aatgttattt 168180 tcatcttcaa tgttaaatcc ttcggatact tcataaagtg tcacccataa atcacctata 168240 tcgatagtag cattttcctt tccatgactt tcaagagcat gacaaatttt cttaatttcg 168300 tcataactca ttttaataat atcatctcct tgactaagaa agatgtcatt tttaaattca 168360 acacgaatta aaccgcttcc acttgaaata aacatatttc ctcactttga aatcatagtt 168420 ggaataacag aatcaagata agtctttaac gcaatagctt cgtctttgtt taatgtaatg 168480 atatgtgatc gaaaatcgtc aatttgacga atagatacta catctccctc ttcatagcat 168540 tttgacacat ttaaaatagt ttcatcattc tgattgcaag cgttagtaat aatagcattg 168600 caatttttga gccgttttaa actatgtttt ctttcattag aataataaaa atatttaatc 168660 ttagctataa aactatccca atggataact gataaacaca ttgactcact ttcaatgtta 168720 aatcctgggc atgaagaata aaaatgaatt ttgtgctcat cattgatgct tactatttta 168780 tcagcataag gatattcaat ttgggttaaa tgaataattt cactaggtgt aaaatacagc 168840 atatcgtctt cttgcgtcaa acgatacatg ttatttactt tttctatagc caattcacca 168900 aaaagcggac taacttctaa tactaatcgt ttcatattaa tcctttttat tggcacgaat 168960 ttgttctaaa attttagaat attcctttgt atcagattta cgtacaattg atacactata 169020 aggcatacta tcggtgtctt ttataaagcg ttccaaatga cactctaaca aaatttctgg 169080 attataaatc gtgtacatca aattacctgt tgctccacga tattggcaga tttctactga 169140 ttgaacacca ttccataatt ttgttaaaac taaatcacct acttctaatt taggaaagcc 169200 catgttattc accaattaaa gtttcaatat aagaatcaag atttacttta gcttcttcca 169260 taagagtttt gtatttaatc ttgttagcat gtccggagaa agctgattca tcaataattg 169320 ttgatgtatg aacagcttta ctatacgtct caattaattc tcttaattta aaagcctgct 169380 cacttgtcat tacatactcc tttgaataat atcaataatg ttgttcacca gattataagt 169440 aaacattggg taattatatt gaatcatcac atacacaaca aacaaaactt tcattctctt 169500 ctccttggca gttgacaaga ttactatacc ataaccttgc caacttgtaa accattaaat 169560 gacgttttca ataaaattct gaagctttgt gtgagcatca accatgattt tcatttcttc 169620 tttggcgaaa gctatacctc tttcccgaga agaacattca tagtcagaaa ctgcgttagc 169680 atattcttca attagtttca ttaaaaacat ctgcttttca gttttcatta ttccacctaa 169740 tcatttcaag atattgaact aacttagctt tggatttatc caaatccttt ttagctgctt 169800 ctata 169805                          SEQUENCE LISTING <110> Optipharm.CO., LTD   <120> Novel Salmonella specific bacteriophage SG1 and antibacterial        composition comprising the same <130> 1-40P-1 <150> 10-2016-0177916 <151> 2016-12-23 <160> 1 <170> PatentIn version 3.2 <210> 1 <211> 169805 <212> DNA <213> Direct input <400> 1 accgtcgtat gaatatcctt cacaatgctc aactgctaat tgatatgaat ctatttcaat 60 atcacgtgct aatttaatga ttttttcaaa ctgttcgcgt gttagcatac ttacactctc 120 gtattatgat tgataatttc atcaagaaac atatctaacg cttctacagc attatcaact 180 ttagcttcaa attcttcaat acctgataag gcaaagttaa tgcgttcctc atctgcttta 240 cgaattaaag ctatcaattc cttaatttta tccgcttgtt cgatactaat cattattcca 300 ccacatatga aagagagaat attgcacacg ccatgtgaat tgcaacttca tcacacatat 360 tataacgttt cttaagaagt tctacaagtt cttcactagt gacttcatcc atgtcgacga 420 aaaaatcacc attaatgatg acgtagatat ttccttcttg attaagtgct tcaattttca 480 tgatgttctc ctctttatcc gatggttgta tagtaccatg gctcaaacgg aaagtaaacc 540 ggtaaaatga aaaaagtctc ccgaaggaga ctaatgttat tcgagggaaa gaagatactt 600 actctggtaa aacattccag taatatcatc tatcgtgctt tggatggctg gaggcatttc 660 tttataaatg ctgttagatt ggtctagtat gcgatcaatc attttaattg tgtcggtagg 720 aagtttacta gcatctggaa ttgaaggtgt gtattttcta ccagaatacc ccaaatattg 780 ctcaccaaat ttatcaatca aatctggcaa ctcggagaaa ataaaatcgt atgctttgtg 840 tctagcataa tttttagttt caaaatgtgc agaatgaaaa taagcttgtg cagccattaa 900 taaacctaag tattcatctg cctttgaagg ttttccactt tgtgaaaagt cgctgaattt 960 cattcagtct ccaatttaat gttcataatt ctagcgtatg attgtgccat ctccgcgcct 1020 cgttctatac attcaaaatc agaagagcac gggtcatttt tataggtcgt tctcataaaa 1080 ctatagaatt gttcagacga ttctacgctt ttattttcaa aaagcatata aacgtgccta 1140 ataccagatt ccataaattt atcaaaatga ggatcgacat tcgcttcaat tggtggagat 1200 aaaacaaatg acaatcctag catggcaaat agtgccgttg cttttaaggc cataaaggcc 1260 tcctatcatt tttgccctgt atttacttta tgccgatgca cggccttaac tttatcaagg 1320 tatttttcaa aatttcgcaa tctagtatag tctgccggag attggttgag tgatacttct 1380 cgacgcaaag ctgaaatgat atttccaact tccctacgaa tttcatctaa ttgaagaaca 1440 gtaagattgc gaagttgctt ttcagttaat tgtagcatat ataccccttt agttagataa 1500 acctatttat aacttttgca ctaaccgagc tttttagtta attcattcca atgttttcta 1560 cacaaagaaa cataaatttc atcaccaata cagatttgat taccttcttt aactggtgtt 1620 ccatcttcca ttaatcgagc tgtcataata gcttttttac cacaatgaca aactgccttt 1680 agttcaataa gtttatctgc aatcgccaaa agttctttag aaccttcaaa taattttcca 1740 gcgaaatcag tccttagccc ataagccata acaggaacat tatatgtatc aacaattcga 1800 cttaattgat gcacctgttc agtttttaaa aactgagctt catctacaaa tacacaatga 1860 atatcttttt gtgcttcagc ccatttatag aactcaaaaa tatccatatc atccgtaata 1920 atattcgctt cctgcttaat tccaatgcga gaaacgactt cacagacaga atcgcgagta 1980 tcaatagcag gcttaagaac taatacaccc attccgcgtt ctttataatt atgtgcagca 2040 gtcaaaagag aagcagattt tccagcattc attgctgcat aagtaaaaat taaactcgcc 2100 atcttagtcc ttagttaaat tttctaaata tgtttctaaa tcattttcag ctttatcgat 2160 agattttact aattcgtaat atgtttcggc atctccatat tcagaagata tttcaaaaga 2220 caaatccttt tctaaactaa taatttcacc aactaaaaaat aatatttcgt tcttttgttc 2280 gcgagtaatc ataaggaatt tatataatta ataagttctt gttctttatt atcgaattct 2340 ttagaaagtt cttcgtattc gtcagtatta aaaggaccgc attcattaca aactttttcc 2400 aattcactat ttttatccat aacttcgtgg ataagagaaa agagtttgtc tttttgttct 2460 ttgcttaggc tcatatatta atttccagaa gttttaaaat aattcgcttt tgcttaaata 2520 tttccatagt taaatgatca gtatcttttt ggccaattcc aatggcaaaa cctttattag 2580 cagcgagttc aattaaatta tcaagttcac gtgacacttc atattgtaac tcagaactat 2640 tcatttcggt ttaccttctt taacgaaatc tggataagga taaaatcccg aataaaatcc 2700 ttcaccttta tgattgatgc atcctttatt agaacaatag caccaataat cgaaatcaca 2760 agccatttca tcgttgcata aagcaaaaac aactggccat ttacactttt cacaatgggc 2820 atttttaaga atactagttt ggctcataac catgtcacct ttaagcagta ttcttctaca 2880 tgctgtttac gacctttctt atcaataaag gtatattcaa cgaatgttcc aatgtagtct 2940 ttatctacat catgcggact attaattgga catttagtac ggcaaatgcg ttcccattga 3000 cgaataatta ctgccttatt ctttgggtca tatggatgtg gataatgtat attcataata 3060 atggttccca atcaacaatc acaatttcta atttagagga atatgtatct aaaatcccct 3120 caataatatc ccagttccct ttacctatgc ctgcaccaat cctaggcata tagattgtag 3180 gtttaatcag tttattttca ccaaactcat ttaattctaa catacaattc attaaagcga 3240 aatactcaaa atttggcccc ggttgaaatt gagtataaag attaaagcag taagctttat 3300 gagtcctaaa gtatttttca tagactgagt aagaaccaag tttagttaca tcaccccatt 3360 cagtctgtaa tttatcagct tccaaaattt tagggaaagc tttggttaat tgacctgcga 3420 ctccagcttt catcgtatga aaacaattgc atccatgcgc aatattttta ccttcagcga 3480 aaagggcgac aatatcgccc ttgatatatt ttacaatcat ttagtactca atcctcgatt 3540 ataagaatct accaaacggt caaccattga atgacaagcg gctttatctt tctcctccgc 3600 aactgaacat tctaaggtat tccacttttt agcatatcgt tttaataatg tatcgttttt 3660 gtatctgctt gatttatctc tttctccatc tttatatgca tatattaatt tctgcgcaaa 3720 ttcagcttgg catgctttat ttttcccaca ataatctgcc gcagtgcgat ttacatattc 3780 tctaatttca gtatatgatg tatctgctaa cgcagaagca gaaaatgaaa ttaatcctat 3840 acataaaacc aaaattttag tcatttacta tttccaaaag tttattattt ttaaggtaat 3900 tagccttttc taggacttca gaagcatatt tagaaccagc tttaacattc catcccgaat 3960 tataagagga tattgctttt cttatatctc ccttgtgtat atttaaccaa taagaaagtt 4020 caatgtacgc ccaggaagct gaattggacc gtttattcaa cattcttttt atttcagcat 4080 cggtcatatt ataaccaagt tccttaactc ttgctcgcat agtaggcaaa taattttgga 4140 acattccgta ggcgtgatgc tttggtttag attttaaatt aactccgcca gagctttctt 4200 gccataaaat agcagccatt atatgaccta atccgctctt gtggatattt ttatgtgttt 4260 tatattttcc atccttagaa aattgttccc cgaattgata cgcgtaacgc atgttatcga 4320 gttggacatt actgaaagta tgctcggagc tatgtgccat cattgaaatg gccaatagac 4380 cagcgagtag tgcttttctc atgcttacct cattgagttt taattactgc tttagaagcc 4440 tttcctggta aacgacgact gttaataatt gccatcctac attgaagtga cgggtctttg 4500 aacttcgcgt taggtttaca aactgtaaat ccaagccaaa gatttccatc tgtgatttct 4560 agacgtccag gacgatattc aaccccatca ataaaatcct cgtcaatgtc aggacgcgga 4620 ggcatactca ggaattcatt aacttctaaa acatggtctt ttattttatg gaataattca 4680 aaaacatatg tctcatcaat ctcccgttga attgcgcgat caagaagatg ttgagaatat 4740 tttagatgaa acgatgagac tcctgctgct tttgatgcct cacgaatctc attgttaatt 4800 tgacgaaact ccgactcaaa gtgacgacga agcttatttc gacggataaa aacttctgta 4860 ttgatagtca tgttattctc ctcttaactg atagaaaaat tataccacag tcaagaggaa 4920 aagtaaacag ttattcttta aatctaatca atttattcat agactttgaa acatctgcac 4980 gaacctcatg tagatttttg agctgttcaa gacgctgctc atagtaagca atttcatctt 5040 cttcgagaca gtcctgtgaa tcttctttaa gataacgtgc atagtcctgg aaagcgttac 5100 gaactacttc ctggaagtca tcaagacttt gaattttctt aggagcaaca gatacacgac 5160 gaggggcagt ataatactca taaccaaacc ctgcgcttaa ttgagccatt agtatttttc 5220 ctctggttgg aacactgcac gacaagccca catactggct tctttgagtt tcgttttagc 5280 aatagttaac tgatcgagac tttcagcata attcttcgcg aattcacagt cttcacaatt 5340 atctagcgct tcccagaatt catcatataa agcatcaaag ataagtccta aacgaacttc 5400 agcgtctttg atagcattca ctttactgat tttatcgtca gtatgtggct tataaccttt 5460 aatgtcttca atcatatttg acttcctcac cagtacataa atcatattca actaaacgaa 5520 taggttcatg aatgccatat ccttgaacag aaatttctgt cgtaggataa attccatcaa 5580 tatcacccat ggtccacgct tcattaaatt gctgttcgcc tgaattacta aaccactcgg 5640 cgaaagcatt tagcacatct tcagaacctt caataattat ctttgccatt acaaactctc 5700 agtaaaggta cgagcaataa cgtcgcgctg ctgttccgga gtcagagagt taaagcgaac 5760 tgcataaccg gatacacgga tggtcaactg cggatatttt tccggatgct taactgcatc 5820 ttccagagtt tcacgacgca gaacgttaac gttcaggtgt tgaccacctt caattttaac 5880 tgtaggctgt gattcaattt caatttcacg ggtatgcaaa ccgtagaaaa tttctgggtc 5940 tacaaaagag tcctctttaa aagttttaga gacaataatt cttgcttgaa taccgtcttc 6000 aaaataaata gtacctttat gcgtgccttc aagaatttga tatgctttca tataacctct 6060 caattagaaa ataaatttat ccaagattgt tctttaatta aaaatggctc agaatcatat 6120 gccattaaac tttgggtgat tagtccttta aaaggtccat caataaattc catggtaaaa 6180 tatggaattt tattcattaa tcttgcatta ggagcagtgc acaaaactct gcatcctttg 6240 aatacgcctt tttgtaattt gtattgctta ggataaaatt cgctcaagac gttattattt 6300 gccaaaattt caaaatgatt caccaattta tttttaatag tttttggcga aaaataaaga 6360 tattcgaaaa gttgcgtgtc tgtcatcatt gcattccgat tacgaaaaac tgcggacgag 6420 taataccacc aatgcaacaa ttactattgc aacagtggtg cacagtttca atatgaatat 6480 cgtaaatttt atccatatca ggagatttaa caggctcatc gattatatac aaaattcgtg 6540 aaagcgataa acctctgaac ttgctacctc tattaccaac aaaactacgg acagaatcag 6600 taaataaacg gaatcgaata tcatcattag aatagcgtga aaattctttt ttaatgtggc 6660 ccgcagaaat tttagcgtaa gctgaagtat tagaaagaac aataactgtt ccaccgtcat 6720 acaaccaatt agcggcaaaa ttagttactg cagttgattt accggattga cgtccaccat 6780 ctagtcgaag tgtgcaatac tgttttagta agtcttcaaa tggtgggata taatcgtttt 6840 tacaaatttc ttctactcta gcatcagaat ggtgtgtaaa agcattcatc agggatagat 6900 aaggaccagt taaaaatgtt ctcattttgt tctctctagg tttgggccat tccatggcgc 6960 atgaattgtc catttctgta tttacccatt accgcacttg ggctcgacct tattacaggt 7020 tggcgggaat ccctcacaga atcatgaggt ccaggttgtt cccatattat ttgaacgatt 7080 taacgtactg aatagaacct ttactattca cgaaagcgat tttaccattt ttattataca 7140 tggtagcagt acgctgatag ccataagttt gcttaccaga ttgataacca actaatgcaa 7200 aattatcttc acccatttta ttctgtttag cgcgaatgcg ttcatgacca tgtgccataa 7260 gaaccttagc atcaccagtt gcaatggatc gacgagtttt ttcatcttca actgtattaa 7320 caaagtcgtc aaatgaatca aatttagcat gagatttatt atacagtttt ccatctactg 7380 cataattata tccctgtaca tccatctcaa cttctgtacc atcatccaat acagcagtga 7440 ttttctgtcc ttttttaaat ttcaaaagat cagtaaaaga ttcagcaata atttgagaat 7500 taatagctgc ttcagtaata aattcttgat atgttttcat gtgtttcctt taaatgtaaa 7560 tattttaatt ggtaattgtc tattcaagta actgtgaata tactatcaca attctaagag 7620 aaagtaaaca gctttataga tttttatacg cgtcccaagt gccagttcta aacgtagcaa 7680 tgactcgttt tgcgcgatta ggtgtttgat tataccatcg acttttagct aagttaactg 7740 ctgcttcatc ccagcgtttt tgttggagca tacgtaaaga attagtaaat cctgctacgc 7800 cagtttctcc catttggaag accatattaa tcaatgcaca gcggcgaaca gcatcaagag 7860 aatcataaac tggttttaat ttagcatttc tcagaattcc gcgaacagca gcatcaacat 7920 cctgattaaa gagtttttca gcctcatctt ttgtaattac accattgcaa ttacgcccaa 7980 tagctttatc taattcagat ttagcaacat taagtgatgg actttttgta agcaaatgac 8040 caatgccagt agtgtaatag ccttctgtgt ctttatagat tttaagtcta agaccttcat 8100 ctatacgtaa catttcaaat atattcataa tacctcctaa gtatttatag aaggtattta 8160 taaattaaaa gaggttgttc attattcggt aaagtgaagg acccatcaca tattgccact 8220 gagtacgagg aataagagca aaagcgtcca tctctggaat cataacacca tctttatttt 8280 caaaataaga ctcgcaatgg caatttctaa acatctcatg ctctactgga atcgtataat 8340 aaaatagctg taagtcttta ttactagaat atttaaatac acctaggtct tctagaaggt 8400 ctggattata attgctaaaa ccggtctctt ctaagcattc tctttttgca gcttccagtg 8460 cattcaaatc agaactttct acacggccct ttggaatatc ccagcggtgt gccatcattc 8520 caggcttacg agaaccagta acccgaccca taaataaatc tttatcttct gtcataaaga 8580 taataccagc tgataaggtt ttcattttaa tttcctgcat tcagtgataa agttatttaa 8640 attttgagca tatttctttt catcaaaaat cttttgctgt ctgcgtaaac gccatggcat 8700 ttcaatgaac atacgcccat attcctgata atactgctgc tgtaaaaata ttaacaagta 8760 tagttaaaag aacccaatct cctattctgt ccattggatt ttttataaaa aagtaaaata 8820 cgaacgatga tataggaaga ctaatgatat accacagaat aaccttctta tctgtgaacc 8880 aatcggcatt cgttaactta gcgcgaccat tttgaataca cacgaattta tcatctgtta 8940 cagtaaatgg tttagctgct tgatatccca ttctaaactc cctaattaat cgtttctttg 9000 tatcttcgga acaaccattc caatcaactc tatcaactga aatgccatca tccccatcat 9060 ctaaatcata ccagcgagtt tttaaaatca tttaattttc ctgcaatcgc tcacaaactc 9120 tttcattgat tcattttcaa tataagacat gtagctatta tattctttta attgtatttt 9180 gtaatccttt tttctttgcc aattatatttt aaaattatca taatgaaaat ataacattgt 9240 accaaagaat gaaaataatg aaatcgctat agtaaaacga agttcactcc aaacttctat 9300 tatatctatt ataccgctga cgttactacg gatgtttaaa ataagacagt caattaacaa 9360 tccaaaaaga ctacctgcaa gagctgcaaa tgctgatacg gcaagaatta atagtgcctc 9420 tggaaacgaa tatttaactt tatttagttt tggcttttgc atcgtgattc cttaacaaat 9480 ttcataattt catcaaattc atacgcggca agtttaagct gatgttcatt tttaatcttt 9540 ttacactgtg ctttccaatc acgtacacgt ttacgataat gtcttccttg ataccaatat 9600 cctatccaat ttacaggtac taataaaagt ggaactatta atggaagaat tagcattaac 9660 acaagtattt cgccagaatc aatatcagtc ataacatcta aaacacctcc aataatcaat 9720 agaattacaa atgatatgag tataacagga cctattaaca catcagtagg aattatctgg 9780 cgctttaatt catactttaa gggtttactt ggaagataca ttgatggctt tgacatattc 9840 tctacattcc ttaacaaatt tttctagtaa taaatcactt tcaaaattag gattttccac 9900 taatttatca aaaagatcat caacaatatt caagatattt cttttactaa gaatacgttt 9960 attttcatgc ttcgtttcag aatcaactat aagagtaaag aaatatttct ttccctgaaa 10020 ttttactgta gtatcaatat agaataaatt tgacttttgt aagttacgtt taaaccatgc 10080 gtcacttaaa ctataaacac cgagataatc aaaatcgtcg tttaaataac atactgtcca 10140 ttcaggagaa atgaaatcag taaattcaac atcaaaatca cacgtcaatg aatgaattga 10200 ttcaatactg ttaataagta ttccaggacg tattaaagac tttttacctc tggaaaatct 10260 tccagaaaga ctttcattag tttcatatga agaaccccaa taataattac gtccttctgc 10320 catacgttta agagcattta gtaattggtc tggaacatca acttgtcttt ggaattcttc 10380 aaacattgaa ttgaaatcac tttgcatttt cattcctatt tactccaagt aataggggcc 10440 gaagcccctt atcattattt cagagaatta atgtattcct gaacatcggc agaggtagtt 10500 tcaaccccag aaatattacc attaaaggtt tcaactcgag caagggtatc ttcaatatca 10560 accttagtca gtgctgcaat ttcaactaca tcatcagcag tactaattcc aagggcattt 10620 gctgcacgag tttcacggat atattccaat ttaactgcaa gttcttggcg agcatcatct 10680 aactcaacta ctttcttggc gatttcaatt cgcatttcag cataaccgtc agccttagta 10740 gtcaactgtt cagctgttcg acgatatagc aaaccgagtt tagcatgcat tgttacatct 10800 tgaccttcgg aaagaagctt gcgaatttca cgctcttttg attcagcctg tttattcttt 10860 tcaacgataa gttcacgaat acgtttttct tcattaatag atttaacaga agcagttttt 10920 agatctttaa ttttatcaag cagttttgct gctgcggcag tatactgttc ttcaacagat 10980 aaatttttag ccatagcaga accaagttta gtgcgaataa actcaacaat tttcttcagt 11040 gtgttcatag tatttcctta ggttgattaa gatttaaaat ctgtggaaga attatatccc 11100 attatttgag agatgtaaac tatttttaat tttacaaatt cgttcagctt catcgatagc 11160 agcattaata atgcttttag ctataggagt actaatacta gtagctttta cacttaacac 11220 gatttcttta tctttaccag gccaacccca cgatttttca ccatgagtgc ctttaattac 11280 agcagacacc tcaagtgagc atccattatc gcatgttttt acattaacaa cccaagtgtc 11340 acttttctca accggtttat cccagtaaat attaagaata cgtgggacat caaatttagc 11400 agggcaaatc ttaaccgtaa gaccttcgct ttctagccaa ttaataagag ggcgttcata 11460 catgcggcga tgtgggcttt gaactcgaca agctttgtac ccattgcttg cggcttcact 11520 aagctcttct aatacctgct tttgcattat tgataagata tcatcaaaag atttttcgga 11580 agtttcattc agttcggtat aaagagacat aacagtttcc tcaaattata ggctcataat 11640 atctcaatca tgagcctatg taaacttatt tcatattatt aaaatattct tctgcgattt 11700 cgtcgttatc atggtaaact ttagaagaca gtttaacata accttctgct gtgaacatgt 11760 taatcacaac ctttacagta taccactgac catcttcatt acccattact gcgtaagttt 11820 caaacatcgg atggtcagga ccgataactt taatatcatt cactgtacga ccgaaatctt 11880 ctgaaacaca tttcataaag aagttgaaca gttcgccgta attatccatt tcattctcca 11940 agttgttttt ctgtatcagt agttgatagt tgtatagtac catggaagga caaggatgta 12000 aaccgttttg tgaaaaattt tttaaaaagt tttagggaat tctagggcag ggaggggcaa 12060 ttaaaagata ggataatata ttataaaggg tagaaactaa atgatgtcta gagaggcctg 12120 gaaaggccta gataccaaaa agccccaacc ttttggctag ggctaagaat gttatttgat 12180 ttgtttagca gaccaaatgc ggtctttaat aattttttgg atgtcttcaa catactcaag 12240 agagtgagca tgtgggttat ctttgaaact ataagcacga gctagctttt ggccttcagt 12300 tttgattact aaaagctctt taaggatagc ttcatattta gcgataattc ctttaacaat 12360 atttttttct tgtgcagctt taggatctgc tttaggagca ggtttacccg aagcctttgc 12420 aaaagcagcg ccagtagcaa ctagactttt ccaggccata ctaactgcat ttcccgtaaa 12480 tccttctgct ttcatgtcgc gagcaaattg gaatcgtgat tcgtcagaag catctttata 12540 ggaatattta cccgctgcaa tggctgcttt tgcgacagct tgaatttcgg tgctagatgc 12600 ttcatttaac accgcttcat ttaaaaattg agcatatgat ttcatcttat ttcctgtttt 12660 aattcgtgga tttaatatac tactatattt atactaaaaa gccccaacct ttcggtcggg 12720 gctaagcctt gcggcaacct tgtcggggtt ccacctgcta aggcaagtgt ttgtacgaaa 12780 cgccgggatt tgaacccggt tattaagtag ttgacgctac tcaatatttt taaaaggcca 12840 tatctcgacc atatccgaac gttccgtcaa aaacgctact cggcttatgg caaagatatt 12900 tcctcgaatc gataattcgg tgcgccgttt ctgctgtgat gtaagagggc atcaataaac 12960 gtaaagatta ttaacgcaat tccttactca gggaacatca gtccgacgac ttaccggtag 13020 cgacccggtt tcttaatatt cttttaaaga atcaatatat tcacggcgtt tacgccacaa 13080 atcaattgct tcatacgcgg attcagcatt tcgaattagc cggcatttat gtaaagactt 13140 atgattttga tattgtgtag ataacggaat tgtatctaaa aggtctttac gatcaaaata 13200 ttcgtaacca tctaaaccaa atgaacgatt tttgagaaat tgccaatgac catattcgtt 13260 ttcgacataa acataatctg catgctgata aagcaaatta attacacgtt cagaaataac 13320 agtatcatta tgattaaaat agaatgttaa atcatgaact actaaataaa cattaccttt 13380 catattttcc tcacttataa ttggtcgagg cagaaggatt ctaaccttca acctacggat 13440 tagaagtccg ttgctctata caattgagct atgccccgta attaaaattt catttttcga 13500 cctttaaacc atccttctgg aattgggtca gttttcttaa tacgtttaga aactttttca 13560 tctaatgaat gaatccacat cataccaaat tgggaattct tttcgccctg ttggtgttta 13620 tttctggtgt gagattcttt cattttatta atagtttcag gagtatggga cttacccaag 13680 aaagatttag tatttaaaaa tttctctcta tacttaggat tatcccaaag ctgtttaaac 13740 ctttctgaac ccattttacg atatttttct ttaaggtctg ggtcgttctc aaatctggtt 13800 ttaaaagcgg cagccccttt taaggaagct tctttctttt tatccaaata ttctttagtg 13860 tttaaatggt cccatccacc ttcaccacct aatttcaaat tataaacatc agggcgcttt 13920 aaaaactctt cagtcacaat attcttttct gactcaaaca tagaggtttt atcgtcaaag 13980 aactctaata tttctttaga aaaattttct ataccatact tatcttgggc tctttttaat 14040 aatttaccag aacccatata tccatcatct aaattttcgg tagaatgagc gcctatatag 14100 attttattat taattttatt tgttatttta taaatgtaat ggaacataaa tatctcctat 14160 ttctaagagt atttatgttc ccaaaatatg gccctgggtg gaattgaacc accatctggc 14220 gattatgagt cgcttgcttg aaccttccag ctacagggcc ttgatatgct gattgacgga 14280 atcgaaccgc cgacgtcctc attacaagtg aggtgctcta cctactgagc taaatcagca 14340 acggaggcga taggatttga acctatgagt cgccggagcg actgccggtt ttcaagaccg 14400 gtgcattaaa ccactctgcc acgcctccag tctccgtggc aggatttgaa cctacgacat 14460 tctgctccca aagcagacgc tctaccaaac tgagctacac ggagtaaatt aaatttgagc 14520 ggataatgag aatcgaactc acatcatcag attggaagtc tgaggtaatg ccattatacg 14580 atatccgcaa actttggtac gagaagtggg actcgaaccc acaaggaaat cattccgcag 14640 cattttaagt gctgtgcctt taccaatttg gccattctcg cgctgggaat aaaggactcg 14700 aacctttgca tcctggaatc aaaatccagt gccttaccaa cttggctaat tcccaattat 14760 taacaaaggc tcttaagcaa gaacccttga tgatagaggg tattaatcag tgcgatatga 14820 gttaataata acaaataatt cttaaagcat atttaccatt tatgataata catatttacg 14880 atgcattcaa gacccaaagg attcttgaaa atatcatatt caagaggacc tttttctgtt 14940 tcaataaaga aatcaaaatt tactgtatta aatttacggt cttcctttac taatttaact 15000 tgagaagatg aacggtcaat gtaaaccttt tcaacttcaa aacatgttaa aatgccataa 15060 tcatcaatca aggctttagc tgcttcttga tcatatttat atccattttc aatggatgat 15120 actttcgcat aaagaatcat tattaacctt tatcaacaat agtatgtgta tgggcattta 15180 cgatttgcca ccaatcgaaa ctatcgccaa atcgttttga tttattgtct tcaataattt 15240 ggcgtaattc atcttctgtt tcagcatacg caatcaaatc atcatatcca ccgcaaggat 15300 agtaattatc gcctgcgaat aaaagaaaat ttactttaga tgggtttaca taataatgct 15360 ctttaggata tttagttcct ctccaatcag ttacttcaac ataacgataa gaaaatccat 15420 ttttactttc aatccaactc cacgcttcaa aaggagtatt aaaaacttta tcaggtatta 15480 aattaccttc aaaatgagaa ggatttgcat aatccccagc ataaacatag tattcgttaa 15540 tactcacact cattctattc acctttagaa attttatcca taacaatagc tattaaacca 15600 attaaaaatg ctactacaag tgaaaacaca ttttctgctg tagttaataa tccgcatata 15660 aatccaacaa acattgaaaa actaaaagcg gaagcagaaa ttgcaatagc aacatttcga 15720 attaattcac aacgtttcat tttattctcc tcagtagttg atagggtaat agtatcacaa 15780 ctaaaaccct atgtaaacaa ctttgtgaaa tatttattac aaaagatttt tagcaataat 15840 tttgagctga gctactgaaa tatgcttggc tttaaacaaa gcagtttctt cagcaggaga 15900 gataacgatt gtagcaccat cctttttagc agaccaccca tcgcctaggt aaacagtacc 15960 tttgatttct tcgccatcaa ccagactaat cattggttta ccttctcgtc ctttatttgc 16020 tttaataact tcagaagtaa gagtagcttc ggtaatggta gaaaccgggg tagttgtaga 16080 agtaaactct ttgaaagttt tcattttatt ttcctaatta attttgatga gataatagta 16140 tcactacctc atcagcatgt aaacaacttt gtgaaattat tttaaatcat ctgcccaatc 16200 gagtttaaga ggctctttgt attcacgatc taatacgacc ggaatttgta catcaccgct 16260 aaatgataag ggcccaacat tataagacaa tgttatatgc ggtgtgtaat catcaaaatc 16320 atgtgtagca cctagtgccc gcgcatacat gtgtcgacag cgcagatatt cagaatctag 16380 cacaagtaca agagtcgatc catcttgtgt tttccatact tctaaatgtc cagaagaagc 16440 tacttcaaaa cttccgcttg atggaacata cggaacattt actcttgaat aacatatggt 16500 cgaatgaatt ttttctctag gaactggatt aggaacacgt aaagagcgct ggagttcttc 16560 cagcgcatca agtgttaatt ctgaaaactt agctgctaca taaagacccg ttgaaaagtc 16620 tttaaattcc attattcttc atcttttgct tcatcagtag attcagcagt aagattcttg 16680 acagcttcaa cgatttcttc aactttgata gtatcgccag tgatacctac tgcacgagcg 16740 atttcagcca aagttccttg cagaattttg gattcttcca tcagacgagc cgcttggtcc 16800 tgcgtatcaa gaatacgaga cttcagagtt acgatttcag cagacagttt ttgttcaata 16860 gtttgttcag acattatagt acctttagtg tatttttaat tttagaaaaa agttcttcaa 16920 gagaaccatc gtttgtaatt actaaatcgc catcacgaat tggcaatcca gcttctgtaa 16980 tatgtgtatc attggatttt tgaccaggac gaactacatg aattactgta gcacccatcg 17040 ccctagccgc atccatttca tgatcttgac gagtatcagg aacgatataa taatcataac 17100 ctgagttaaa tttatcaaga taatctaaag caaataattt tacccaatac atgcggtcga 17160 agttattaac aatcaaatcc gtacctaggg cttgcatcag acgacggact gaccattgat 17220 cttcaatatt atttataacg tcagcaatct tattaaatgc tacgaaatta actgcgtcat 17280 caaaaacaaa tacgccttta attgggcttt tactattaag atagcaaaat gcttgttcca 17340 taatcgtaat tacttctaat ttagtcagat ttaaattagt ctcacgatca tagtcaattc 17400 cttcaaactc tttacgagtt aagcaaggat agtcagtgtt tgctgcaaat acaccccatg 17460 cataagccaa tgcatcctta ataggaccag caagttgata tttaactgca gaataattat 17520 tcatgataaa atctgcagta gtatcttttc cactacgctt tacaccactt aaaaagatta 17580 gtttcatatg tttctcctca aatttagtta agattataac acatgaaact gaagcattaa 17640 acttctgcta taattttacc atctttttct acttgaaaat acgtataagg aatcgttgct 17700 gtacatacta aagccgggtc tgaatcttcc gtgtagctaa attctacttc agacaggtca 17760 gaaacccaag gcttataaaa atttattgac atcacaattt cagttttact attatctaaa 17820 atgtaaagcg taatgtattc aggacctgtt ttttgggcag tattttcacc tgtaagatag 17880 ttgctagttc ctagcatcca ttcatacatt cctatccacg acttaagttc ttcatcaact 17940 ataaatctca cgatgagtgg atcgtactca aatgtaactc ctggacgctg tgctcggcct 18000 agtccaaacg gcccagtcac ggtatcagta acaggtatcc taattcctgg aataggaact 18060 gactgagcat ttaaagtaaa agcggatgta gtattactat gcggtattga tactacaaag 18120 ttagttgtat ttgcttggtt aaaaatttgt tgcagtgctt gcgacatata ttcctcataa 18180 tgcttcataa atgttggtgg tataatgggt ctaagtccct tccattcaat tccaattaga 18240 acaaacaata gaaaagaatg gaagataata gaattagata tttgaccaga ctttgtttgc 18300 agagaaacgt tttcctttgg agtagaagct ttggagtggc atcaacacaa cgttcgccca 18360 gtctttcggg gcgatttcaa caaggctacc cataatatta ccaggtatat atgccttaat 18420 catttggtct gcacccctaa atcctttcac ttgactccaa tcaattttta atttcgtttt 18480 attagtaata gtaggtgtat tcgaatattg ctttaaaagc tcttctagaa attgctgacg 18540 agctttaggc ggaatatagt gcaagttcaa tccgtacatt aaattatgtt tacctaaacc 18600 aaggtaaatt atcaaaggaa atttatccca gtaaggaaga gtttccttgt gtttagcatc 18660 ataagcaaaa gcatatattc gtcccggctg cgggcgaaca actttatgtc cttttacttg 18720 cttaatagtt tcagcaaacc actttctggt tttattatta attgctgcac cttcattacg 18780 aattttatca cgcaatgttt gcctgaatga atttatcata agcagttgtc tttcttgctt 18840 attgagctta ttcattggtt ttgattcaag attttgaatc ttttcggcag ttttaattcc 18900 tgaagcatat tttgacattg ccgaagtaaa cgtagagtat ttgattcctc tttcttcagc 18960 aaattgcttt cctgtcattc cttttgcttt ggcctttttg tattcaagac ctatctgaat 19020 ccatttcttt tcgtttaatg attgcttaac ctttggaact tggggagtgc tttcattaat 19080 tatttgaaaa atagccatta tgccccctta aagccaagag ctcgtaatcc atcttccgtt 19140 agaattctaa attttattcc acgcttttca gctaaagctt gcgctgcttt ccatttgtca 19200 gtattaacgg aatatgtata aatttcattc ataaatcttt tcttcgctgc agttgttaga 19260 tgtgctggtt taactggtgg ttgtgtttct tttttaggtt ttatttcaat aaaaaattct 19320 tgtccagaag aatctttcat ccaaatatcc atgaagtatc tacgcttttt cccttctgca 19380 ttacaaaaat aaggaattac tgctgtttca ctaccccatg caataatttc tggattttta 19440 tctaaccatt caaaaaagaa tttttcccaa tttgatctat acgtaatttt tttagggtca 19500 cctctatact ttgatatatt tttaggaacc cattttccag aatatgccat tggattctcc 19560 ttataaatag ataatatatt tataaacagg agggcccatg ctctttacat tttttgatcc 19620 gattgaatat gcggccaaaa cggtgaataa aaacgcgccg actattccta tgacagatat 19680 ttttagaaac tataaagact atttcaaacg tgctcttgcg ggataccgct tacgtactta 19740 ttatattaaa ggttcaccac gcccggaaga attagcaaat gctatatatg gaaatccaca 19800 gttgtattgg gttttattga tgtgtaatga taattatgat ccgtattatg gatggattac 19860 ttcacaggaa gctgcttatc aagcatctat acaaaaatac aaaaatgtag gtggagacca 19920 aatagtatat catgtgaatg agaatggtga aaaattttat aatttaatat catacgatga 19980 taatccatat gtttggtatg acaaaggcga taaagctaga aaatatcctc aatatgaagg 20040 agcacttgct gcggtagata cgtatgaagc tgctgttctt gaaaatgaaa aacttcgtca 20100 aataaaaata atagcaaaat cagacatcaa ttcatttatg aacgacctta tacgtataat 20160 ggagaaatct tatggaaatg ataagtaata accttaattg gtttgttggt gttgttgaag 20220 atagaatgga cccattaaaa ttaggtcgtg ttcgtgttcg tgtggttggt ctgcatccac 20280 ctcaaagagc acaaggcgac gtaatgggta ttccaactga taaattacca tggatgtcag 20340 ttattcaacc tataacttct gcagcaatgt ctggaattgg aggctccgtt actggtccgg 20400 tagaaggaac tagagtttat ggtcattttt tagacaaatg gaaaactaac ggaattgtcc 20460 ttggcacata tggtggaata gttcgcgaaa aaccgaatag acttgaagga ttttctgacc 20520 caactgggca gtatcctaga cgtttaggaa atgatactaa cgtactaaac caaggcggag 20580 aagtaggata tgattcgtct tctaacatta tccaagatag caatctagac actgcgataa 20640 atcccgatga tagaccgtta tcagaaattc caactgatga taatccaaat atgtcaatgg 20700 ctgaaatgct tcgccgtgat gaaggattaa gactaaaagt ttattgggat acagaaggat 20760 atccgacaat tggtattggt catcttatca tgaagcagcc agttcgtgat atgaaccaaa 20820 ttaataaagt tttatcaaaa caagttggtc gtgaaattac cggaaatcca ggttctatta 20880 caatggaaga agcggtaact ttatttgagc gtgatttggc tgatatgcaa cgtgacatta 20940 aatcacattc taaagtagga ccagtctggc aagctgtcaa ccgttctcgt caaatggcgt 21000 tagaaaatat ggcatttcag atgggtgttg gtggtgtagc taaatttaac acaatgttaa 21060 ctgctatgtt agccggagat tgggaaaaag catataaagc cggacgtgat tcattgtggt 21120 atcaacaaac aaaaggccgt gcatcccgtg ttaccatgat tattcttaca gggaatttgg 21180 aatcatatgg tgttgaagtg aaaacaccag ctaggtctct atcagcaatg gctgctactg 21240 taactaaatc ttctgaccct gctgatcctc ctattccaaa tgactcgaga attttattca 21300 aagaaccagt ttcttcatat aaaggtgaat atccttatgt gcatacaatg gaaactgaaa 21360 gcggacatat tcaggaattt gatgataccc ctgggcaaga acgatataga ttagttcatc 21420 caactggaac ttatgaagaa gtatcaccgt caggaagaag aacaagaaaa actgttgata 21480 atttgtatga tataacaaat gctgatggta attttttggt agccggtgat aaaaagacta 21540 acgtcggtgg atcagaaatt tattacaaca tggataatcg tttacatca atcgatggaa 21600 gcaatacgat atttgttcga ggagatgaaa cgaaaactgt tgaaggtaat ggaactatcc 21660 tagttaaagg taatgttaaa gtagttattc aaggaacagc agatataacc gttgaacagg 21720 aagcatacat aactgttgaa aaagacacga ctgttaatgt taaccaaaac gcagacataa 21780 gtgttaaaaa taaagcaact gttaatgctg aaaatatgga tgtcaacgtt gagcaagatt 21840 taaatttttc agcgacaaat attaatttaa gtgcatctaa tactgttcat atggatggcg 21900 gggttctttc taaagtatca ggtggaaacg tacaggttgg ttaatatgaa ttataacgaa 21960 attgttgatg aattagttga taccatacaa tcagcttgtt caattattcc cgaaggttat 22020 tatagacgag ttaaatggga attatacaat cccaataaag aaatgattca acccgataat 22080 ggggttgaat gggacactga aattattaaa ttagataccc atctttacac cgaaaatcca 22140 tttggtcatt cttctgatac atttactgaa tcatctgatg gagaaaccca aactggtgtt 22200 ttttgtcata aaatcggcgt gtattttcca actcaaactg cgttagaaga ttacgttgaa 22260 caaattggtg caactttact tccaggtaat acttggtatg gtgctgattt atcgaaacgt 22320 gaatttttta aaactgaaat tgaatatgat atgtatcgca ttgaaaatcg cggaggtaca 22380 tggcatcata cgggtcctag aatagatgct aggacaatga tcggtgttaa caatgactat 22440 acaatgtatg ttaactttaa cggtttagga gattatcgaa gagcatattt aaaatattat 22500 gaagataaac catgcacata tgtcggttta acactaaatt taaatataga tacatcaatt 22560 cccggtattc cttattcacc tccatcaatt attggagagc ttccacttaa tgcaatttca 22620 tgcgttaatt ttactgccca atttccatac aatggcttaa catctgcaat tattgaggct 22680 tggaacacct caagagattc atttaaacta tattgggata tgttgcctgg tatgccggca 22740 attagcggaa gtgattttga aaaatatttt aattcggcat atacacattt atctgtagca 22800 atggaagagc ttggaaattc ggcaattgcc atgtgtcaat atgttcagca acaagccttt 22860 atggttttta aaaattctgt ttcacaagtt ctaaatattg tcggtggcgg atgggattta 22920 ttaaaaagtt ttttacctaa aataacaata atgggcatat ctattgatat tgaagattta 22980 tgtacatcaa cagatggtgt tcaaaaattg aaggaaacct ttgaaaattt taatctggaa 23040 gatactatta gttcaattta ttctgcaatg ggttctgcat atgactattc tatagaacgc 23100 gttaaaatgt attcgcggga tttagttgat gcaataacag atttatatga ttgggcctgg 23160 tcaaaattaa tgatggccgg tgtcgcttta tcaaaattat gtgttgattt agcacaaatc 23220 tggagcatgc cgccaattat tccaaatcca gtgtggtctg ttatcacttt agtgaaggaa 23280 atgatgaaac aaattcctcc attagatatg attatgtcag gtaattttcc tggatttact 23340 gcttctgatg tatatcagat ggttatgtct atcgtatctg aaaaaattaa acaagtttat 23400 actgaaatag aatcattaaa aacccaagca ttggatgtat ggaatgaaat taaactaaaa 23460 acacaggaat ataaaaagca aacgattgaa tttaaacaat atttatcagg aatggctgaa 23520 aaggttgaag atgaaataac tatagcaaaa aagaaagcgt tacaagaagc tgaatccgct 23580 ttaaatgttt taaaggataa atataacagt attaaagact taataaaaaa taaacagatt 23640 tctgtgtctg atgtattaga tttagctttg actgaatttc gaaaaattcc attaatttca 23700 caaatggaat cattattatc tttagctgga gcatctatcg atgatataat gaaagtatat 23760 gaaaatagcg ttactaaagc aaaatcatta tatcacgaat tcaccgatgg cgctcggtca 23820 atgaaagatc tatgcaaatc attatacaat caaatttcga ctttatgttt gagtaaggtt 23880 gtgcaatgga ttaataaaat gcttggaata tttggattaa gtattacatt tccaacagta 23940 tcaatatgca ttccatgctt aaaaactcct atgaggaatt aaaatgacaa ctcctgtaaa 24000 ttatcaatta acaagaacag caaatgctat tcccgagata ttcgtcgggg gtacgtttgc 24060 tgaaataaaa caaaacctca ttgaatggct taatggccaa aatgaatttt tggattatga 24120 ttttgaaggc tcaagattaa acgttctgtg cgaccttttg gcttataata cattgtacat 24180 tcagcagttt ggtaatgctg ctgtgtatga aagctttatg cgtactgcta acttacgaag 24240 ttcagttgtt caagctgcac aagataacgg atatttacct acttcaaaat ccgctgcgca 24300 gaccgaaatt atgttaacat gcaccgacgc attgaatagg aattacatta ctattcctcg 24360 tggtactcgc tttttagcat atgcaaaaga tacttctgtt aatccatata acttcgtttc 24420 taccgaagac gttattgcta ttcgtgataa aaataaccaa tattttccgc gtttaaaatt 24480 ggcccaggga cgtatagtaa gaactgaaat catttatgat aaattaacac ctattatcat 24540 ttatgataaa aatattgata gaaaccaggt taaattatat gttgatggag cggaatggat 24600 taactggacg agaaagtcaa tggttcatgc tggttctaca tcaacaattt actacatgcg 24660 tgaaactatt gatggaaata ctgaatttta ttttggtgaa ggtgagattt ccgttaatgc 24720 ggcagaagga gcattgactg ctaattatat tggaggtctt aaacctactc agaactctac 24780 gattgttatt gagtatatca gtactaacgg tgcagatgcg aatggtgcag tcggattttc 24840 atacgcagat acattaacaa atataactgt catcaatatt aatgaaaacc caaacgatga 24900 cccagatttt gttggggcag atggcggcgg tgacccagaa gatattgaac gtattcgcga 24960 attgggtact attaaacgtg aaacccaaca acgctgcgta actgcaaccg actatgatac 25020 attcgtttca gaaagattcg gttctattat tcaagcggtt cagactttca ctgattctac 25080 taaacctggt tatgcattta ttgctgctaa acctaaatca ggactatatt taactactgt 25140 acaacgtgaa gatattaaaa attatctaaa agattataat ttagctccta ttacaccatc 25200 aattatttct cctaattatc tttttgttaa gactaattta aaagtcacat atgctttaaa 25260 taaactacaa gaatccgagc agtggcttga aggtcaaata attgataaaa ttgatcgcta 25320 ttataccgaa gatgtagaaa tttttaactc atctttcgct aaatctaaga tgttgacata 25380 tgtagatgat gcagatcatt ctatcattgg ctcatccgcg acaattcaaa tggtacgtga 25440 agtacaaaac ttctataaaa cgcctgaagc gggtattaaa tacaataatc aaataaaaga 25500 tcgttctatg gaatctaata cgttttcatt taattctgga cgaaaagttg taaatcctga 25560 tactggttta gaagaagatg tattatatga cgttcatata gtatcaacag accgagattc 25620 taaaggaatt ggcaaagtta ttattggtcc atttgcttct ggcgatgtta cagaaaatga 25680 aaacattcag ccatatacag gcaatgattt taataaatta gcaagttccg atggacgtga 25740 caaatactat gttatcggtg aaataaatta tccagctgac atgatttatt ggaatatcgc 25800 taaaattaat ttaacatccg ataaatttga ggttcagact attgagctat attctgatcc 25860 aatagacgat gttattttca cacgcgatgg ttcactgatc gtatttgaaa atgatttacg 25920 tccacaatac ttaactatcg atttggagcc tatatcacaa tgacagtaaa agcaccttca 25980 gtcactagtc tcagaatttc caagttatcc gcaaatcagg tgcaagtacg ctgggatgac 26040 gttggtgcta atttctacta ttttgtagaa atcgctgaga caaaaacaga ctcgggggaa 26100 aatctcccga gtaatcaata cagatgggtt aacttaggat atactgcaaa taacagcttc 26160 ttttttgata atgctaatcc attgacatcg tacattatta gagtagctac cgctgcgcag 26220 gattttgagc agtctgattg gatttatact gaagagtttg aaacttttgc tacaaatgct 26280 tatacatttc aaaacatgat tgaaatgcaa ttagctaata aattcattca ggaaaaattt 26340 actcttaata attctgacta tgtcaatttt aacaatgaca ctataatggc tgcattgatg 26400 aatgaatcgt ttcaattcag cccatcatat gttgatgttt catcaataag taattttatt 26460 attggtgaaa atgagtatca tgaaatacaa ggttctattc agcaagtatg taaggatatt 26520 aaccgagttt atttgatgga atcagaaggg attctatatc tttttgagcg ttatcaacct 26580 gtagttaaag tatctaatga taaaggacaa acctggaaag ctgtaaagct cttcaatgac 26640 cgcgtaggat atcctttatc taagacagta tattaccaat ctgcgaacac aacatacgtt 26700 ctaggatacg acaagatttt ctatggccgc aaatcgactg atgttagatg gtcagctgat 26760 gatgtcagat ttagttcgca ggatataaca ttcgctaaac tcggtgacca attacatcta 26820 ggatttgatg tagaaatttt tgccacttac gcgactttac cagctaatgt atatcgcatt 26880 gcagaagcta ttacttgcac cgatgattac atttacgttg tcgccagaga caaagttaga 26940 tacataaaaa cgagtaatgc acctatagat tctgatccat tatctccaac gtattcggaa 27000 aggctatttg aacctgatac gatgactata actggaaatc ctaaagcagt atgttataa 27060 atggattcta ttggtgataa agtctttgct cttattattg gtgaagttga aacattaaat 27120 gctaatccta gaacatcaaa aataattgat tctgccgata aaggaatata tgttttaaat 27180 catgccacga aaacatggaa aagagttttt ggcaacactg aagaagaaag aagacgtatt 27240 caacccggat atgcgaatat gtcaactgac ggtaaattag tttctctgtc ttcgagtaat 27300 tttaaatttt taagtgataa tgttgttaat gaccctgaaa ctgcagcaaa atatcagtta 27360 attggtgctg tcaaatatga atttcctcgt gaatggttag ctgataagca ttatcatatg 27420 atggcattta tagcggatga aaaatctgat tgggagactt ttactcctca accaatgaaa 27480 tactacgcag aaccgttctt taactggtct aaaaaatcta acacacgttg ttggataaac 27540 aactctgata gagctgtagt agtttatgct gatttaaaat acaccaaagt tatagaaaat 27600 attccggaaa catcaccaga tagattagtt catgaatact gggatgatgg tgattgtacg 27660 atagtaatgc caaatgttaa attcacggga tttaaaaaat acgcgtctgg gatgcttttt 27720 tataaatctt ctggtgaaat aatttcttac tatgatttta actatcgtgt gagagataca 27780 gtagaaatta tttggaagcc aactgaagta tttttaaaag catttttaca aaaccaagag 27840 catgagactc cttggtcacc agaagaagag cgtggactag ctgaccccga tttaagacca 27900 ttaattggca caatgatgcc tgattcttat ttgctacagg attcgaattt tgaagcattt 27960 tgcgaagcat atattcagta tctttctgat ggatacggaa ctcaatacaa taatttacga 28020 aatttaattc gtaacaaata tccacgagaa gagcatgcat gggaatattt gtggtcagag 28080 atatataaaa gaaacattta tttaaatgct gataaacgcg atgctgttgc gagattcttt 28140 gaatcacgta gctacgattt ttattctact aaaggaattg aagcatcata caagtttctt 28200 tttaaagttc tttataatga agaagttgaa attgaaattg aatctggggc tggtactgaa 28260 tatgatataa tcgttcaatc tgattctttg actgaagatt tagtaggaca aacgatttat 28320 acggcaacag gaagatgtaa tgttacttat atagaaagaa gctattctaa tggtaaattg 28380 caatggaccg taactattca taatcttttg ggaagattga ttgccggtca agaagttaaa 28440 gcagaaagac ttcctagttt tgaaggcgaa attattcgtg gagttaaagg gaaggatttg 28500 cttcaaaata atatagacta tattaataga agtcggtcat attatgtaat gaaaattaaa 28560 tccaatttgc cttcttcccg ctggaaatct gacgttattc gttttgttca tccagtagga 28620 tttggattta tagcaattac ccttttaaca atgtttatta atgttggttt aactcttaaa 28680 cacacagaga ctataattaa taaatacaaa aactataaat gggattctgg attgcctact 28740 gaatatgctg atagagtagc taaattaact ccaaccggtg aaattgagca tgattcagta 28800 acaggcgaag caatttatga gcctggccca atggctggcg tagaatatcc tcttcctgat 28860 gactataatg ctgaaaataa taattcaata tttcaaggtc aattgccatc tgaacgacgt 28920 aaattaatga gtcctctatt tgacgcttct ggaacaacat ttgcacaatt tagagattta 28980 gttaataaac gtctaaaaga taatatagga aatccaagag accctgaaaa tccaacacag 29040 gttaaaatag atgaatgatt caagtgttat ctatcgtgcg atagttactt caaaatttag 29100 aacagaaaaa atgttgaatt tttataattc aattggaagt ggtccggata aaaacactat 29160 ctttatcaca tttggaagat cagaaccgtg gtcatcaaat gaaaatgagg tgggttttgc 29220 cccaccttat ccaaccgatt ctgtattagg cgtaactgac atgtggacgc atatgatggg 29280 aacagtaaaa gttcttccat caatgcttga tgctgttatt cctcgtcgag attggggaga 29340 tactagatat ccggatccgt atacatttag aattaacgat attgtagtgt gtaactcagc 29400 tccttacaac gctactgaat caggcgcagg ctggttagta tatcgttgtt tagatgttcc 29460 tgatactgga atgtgttcaa tcgcatcttt aactgataag gatgaatgcc ttaagctagg 29520 tggaaaatgg actccttctg ttaggtcaat gactcctcct gaaggtcgag gagatgctga 29580 aggaacaatt gaacctgggg acgggtatgt atgggaatat ctttttgaga ttccgcctga 29640 tgtatctata aatagatgca cgaatgaata tatcgtggtt ccttggcccg aggaattaaa 29700 agaagacccg actagatggg gatatgaaga taacctcact tggcagcaag atgattttgg 29760 attaatttac cgtgttaagg caaatactat ccgttttaaa gcatatttag attcagttta 29820 ttttcctgag gctgcattgc cgggaaataa aggatttaga caaatatcaa taatcacgaa 29880 tcctcttgaa gctaaagctc atccaaatga cccaaacgtt aaagctgaaa aggattatta 29940 tgatccggaa gatttaatga ggcattcggg cgaaatgatt tatatggaaa ataggccacc 30000 tattatcatg gcaatggatc aaacagaaga aatcaatatt ctgtttacat tttaacttaa 30060 gggagcccat gggctccctt tttctttata aatactataa actcataagg aaaccgctat 30120 gttcattcaa gaaccaaaga aattgattga taccggcgaa attggtaacg cttctactgg 30180 tgatatctta ttcgacggtg gtaataaaat taatagtgat tttaatgcaa tttataacgc 30240 gtttggcgat cagcgtaaaa tggcagtagc aaatggtact ggtgctgacg gccaaattat 30300 ccatgctact ggatattatc aaaagcattc tatcacagag tacgcaactc cggtgaaagt 30360 tggtactaga catgatattg atacctctac tgtaggtgtt aaagttatca ttgaaagagg 30420 cgaacttggc gactgcgttg aatttattaa ctcaaatgga tctatatcag ttactaatcc 30480 tttaacaatt caagccattg attcaattaa aggtgtttcg ggtaatttag tagtaactag 30540 cccatatagt aaagtaactt tacgctgtat ttcatctgat aattctacat cggtttggaa 30600 ttattctatt gaaagcatgt ttggacaaaa ggaatcacca gctgaaggta catggaatat 30660 ttctacatcc ggatcagttg atattccatt atttcatcgt actgaataca atatggctaa 30720 attgttagtt acatgccaat cagtagatgg aagaaaaatt aaaacggcag aaataaatat 30780 tcttgtagat actgttaatt cagaggtcat ttcttctgaa tatgctgtca tgcgagttgg 30840 gaatgaaacc gaagaagacg aaatcgctaa tattgcattt agtattaaag aaaattacgt 30900 aacggcgact ataagttctt caactgtcgg tatgagagca gcagttaaag ttatcgctac 30960 gcagaaaatc ggggtggctc aataatgaaa caaaatatta atatcggtaa tgttgttgat 31020 gatggtaccg gtgactacct gcgtaaaggt ggtataaaaa taaatgaaaa ctttgatgaa 31080 ctttattatg aacttggtga tggagatgtt ccatattcag ccggtgcctg gaaaacttat 31140 aatgcttcat ctggacaaac actaacggca gaatggggaa aatcatacgc tattaatacc 31200 tcttctggaa gagtaactct acaacttcct aaaggaactg ttaatgatta caacaaggta 31260 attagagcta gagacgtatt cgctacatgg aacatcaatc cagttacttt agtagccgct 31320 tctggtgata ctattaaagg atcatcgtca tcagttgaaa ttaatattca atttagtgat 31380 ttagagctcg tttattgcgc tccaggacgc tgggagtatg tcaaaaataa gcaaatcgat 31440 aaaattatca gttcagacat tagtaatgta gctcgtaaag aatttttagt cgaagttcaa 31500 gggcaaacag actttttaga tgttttccgt ggaactagtt ataatgtcaa taacatcaga 31560 gtaaaacatc gtggtaacga attgtattac ggtgatgtat ttagcgaaaa cagtgacttt 31620 ggctctccgg gcgaaaatga aggcgaatta gttcctcttg atggatttaa tattcgatta 31680 agacagcctt gtaatattgg tgacactgtt caaattgaaa catttatgga tggtgtatca 31740 caatggagaa gttcatatac tagacgccaa ataaaagtac tagattcaaa actaacatca 31800 aagacttctt tagaaggaag catttatgtt actgatttat cggcgatgaa atcaattcca 31860 ttttctgcat ttggattaat tcctggtgaa cctattaatc ctaactctct tgaggttcgt 31920 tttaatggaa ttttacagca gcaggctgga acagctggat atcctctgtt tttgtgtgaa 31980 ggcgctaatt cagatacgca agaaggatgt atatctcttg gtggcgaatg gaaagaatca 32040 aacaccgatt attctataga atatgaagac ggaaaaccta tcagtctttt atttgataga 32100 aaatttgaat ccggtgacat tatcgttata acatggttca ataatgattt aggaactctt 32160 ttagaaaaag atgacatcat tgaattgact gatgaccgtt atgttagtaa agggtcagct 32220 actgaagtta ctggtgatgt ggccttaaca gattttgata aaatcggttg gccaaatgtt 32280 gaaaaagttg attcttatac tagaacgtat aattcaatat catctatttt cgacagcatt 32340 tatcctgttg gttcaattta tgaaaatgct ataaacccaa ataatccggt gacttatatg 32400 ggatttggtt catggaaatt atttggtaaa ggacaagttt tagtaggatg gaatgatgat 32460 gttacagatc caaactttgc attaaacaat aatgatttag attctagcgg aaatccttca 32520 cataccgccg gtggaacagt tggaacaaca acagtgacac ttgaaaacgc aaatcttcct 32580 gcaactaaaa ccgacgaaag agttttaatt gaagacgaaa acggatcagt tattattgga 32640 ggttgccaat atgacccaga tgaaactggt cctatatata caaaatatcg tgaagattac 32700 gcaacaacaa actcttcaca tactcctcct gctaatatta gtaatattca accgtctatt 32760 actgtatacc gttggataag gattgcataa tgagtttact taataataaa gcgggagtta 32820 tttcccgctt agcagatttt cttggtttta gaactaagaa aaatgatatt tcggttatga 32880 ataatcagcc ggtaggcgct gtaacaattt cacaaatagc aaaaggtttt tatgactcaa 32940 atgtagaatc tgctatcaat gatgttagaa atatggcaga gcaacaggtt ggagctgtat 33000 tagttaatat aagcggcgta tctcctactg gcgtgcaaca aacagactat tggtcatttg 33060 aaggaaccgt tactgatact tcagccaaac caggtgatcc agttattgtt aacatgtttg 33120 gtattccagt taaagctact aatggaatga cttcaattga atttactagt gctgttagaa 33180 cagctctaca ggaaatggtt gtaaaattta ttgcaattga ttcgtttgaa gaccatccta 33240 ctatagggaa taaaatacaa gttaagtatt tagataacca agaacatatc ttagagcaat 33300 actctgataa aggaattact ttcaaacaag aaataatttc tccttctaaa cctggatacg 33360 gaacttggca attattaggt gcgcaaactg tcacgctaga tagtcacaca caacctacgg 33420 tattttatta ttttgagaga atagcatgag taacaataca tatcagcacg tatcaaatga 33480 atcaaaatat gttaaattcg atccagtagg atcgaatttt cctgacactg tcacgacagt 33540 gcagtctgca ttatcaaaaa taagtaatat cggtgtaaat ggtattcctg atgcaactat 33600 ggaagttaaa ggaatagcaa tgattgcgtc agagcaagag gttttagatg gaactaataa 33660 ttctaaaatc gttacaccag ctacattagc aacaagatta ttgtatccaa atgctactga 33720 aactaagtat ggtttaacgc gctattcaac aaatgaagaa acattagaag gctcagataa 33780 taattcatca ataacgccgc aaaaactgaa ataccatact gacgatgtgt tcaaaaatag 33840 atattcgtct gagtcatcaa acggggttat taaaatatca tctacacctg cagctttagc 33900 tggagttgat gatactacgg caatgactcc attaaaaacg caaaaacttg caataaaatt 33960 aatttcacaa atagctcctt ccgaagatac tgcatcagaa tctgtgagag gtgtagttca 34020 attatctact gttgcgcaaa ctcgtcaagg aactctccgc gaaggatatg caatttctcc 34080 gtataccttt atgaattctg ttgcaacaca agaatataag ggtgttatac gtttaggaac 34140 acaatcggaa attaacagta atttaggaga tgttgcagta acaggtgaaa cactaaatgg 34200 tcgaggagct actggttcta tgcgtggggt ggtaaaatta acgacgcaag ccggtattgc 34260 ccctgaaggt gatagctctg gagcattagc atggaacgca gatgtaatta atactcgtgg 34320 tggacaaact attaatggtt ctttaaattt agaccatctt acagcaaacg gaatttggtc 34380 gcgcggcgga atgtggaaaa atggcgatca acctgttgcc actgaaagat atgcgtcaga 34440 aagagttcca gttggaacta ttatgatgtt tgcgggagat tcggcacctc cgggttggat 34500 tatgtgccac ggtggaacag tgtcaggaga tcaatatcct gattatagaa acacagttgg 34560 aacaagattt ggtggggatt ggaataatcc agggattcct gatatgcgag gtcttttcgt 34620 cagaggagct ggcacaggag gtcatatttt aaatcaacga ggacaagatg gttatgggaa 34680 ggatagactt ggtgtaggat gtgacggaat gcatgttggt ggtgttcaag cacaacaaat 34740 gtcataccat aaacacgccg gtggttgggg ggaaaataac agaagtgtag gcccatttgg 34800 cgcgtctgtt tatcaaggat atcttggaac tagaaaatat tccgactggg ataatgcttc 34860 atacttcact aatgatggat ttgaattggg tggaccgaga gatgcacttg gtacacttaa 34920 tcgtgaagga ttaattggtt atgaaactag accatggaat atatcattaa actatattat 34980 taaaattcat tactaaggat tacaaatgat tgaattaaaa gagttacctt ttgttgatag 35040 cgttcctggc gaaggtcagg agcgtatttc atggattaaa aatggtgaag aaatattagg 35100 agctagtact aagtatggaa acgatggatc aatgaataga ccaactgttt ccgtgtttaa 35160 aaatgttgag gttcttgacg aaaatatagg aattcttaaa acagcattag aaacatccca 35220 ggaagatatt aaaaccattc agggtatctt agatgtatct ggtgatatag aagctttatc 35280 gcaaataagt atcaataaaa aggatatcac tgatcttaaa acgcttacga gtgaacatac 35340 cgaaatatta aatggaacta ataatactgt cgatagcatt cttgctgaca ttggtccatt 35400 taattcgcaa gcaaattcag tttatagaac gattagaaat gatttgttat ggattaaaag 35460 ggaattagga caatatgctg ggcaagacat taacggtctt cctgttgtag gaaatagcag 35520 cactggtatg aagcaccgta tcattaataa tacagatgct ataacttccc aaggaatacg 35580 cctaagtgat ttggaagaaa aatttattga atctgatgta ggttcgctta caatcgaagt 35640 aggaaatctt agacaggaat taggacaaag accgccttca tttagtgaaa gtatatattc 35700 acgtgttcat aatttagatc aatcgcagat taatcttagt tccgaaatta aatctatcaa 35760 aacttctatt ggatatccag gaaatacttc aataatcaca gatgttaaca ctaataccca 35820 agaaatttca gctttaaatg atgaactaaa taaaagcgga ggtgttaaac agcgattaac 35880 tgtcattgaa acatcaattg gctcagatga tattccttct agtattaaag gtcaaattaa 35940 agataatact acctctattg agtctttaaa tggaattgta ggtgaaaaca cctcgtctgg 36000 tttaagagct aatgtttcgt ggttaaacca aattgttgga actgattcta gtggaggtca 36060 gccttctcct cctgggtctc ttttaaatag ggtttcaact gttgaaactt cagttaatag 36120 actgaacaat gatgttcaaa acttacaagt tgaaattggt aataacaatt ccggaattaa 36180 aggccaagtt gttgcactaa ataaactagt aagcggcaca aatccaaatg gttcaacagt 36240 agaagagcgc ggattaacta attcaataaa ggctaatgaa actaacattt cttctattaa 36300 tcaagaaatg cgtagtatta aaagtaatgt atcttcatta cagggggatg ttcagacttt 36360 acaggaagca ggttatatcc ctgaagctcc aaaggatggt caagcttacg ttcgtaaaga 36420 cggcgaatgg gtactacttt ctaccttttt atcaccagca taacatgggg ccgcaaggcc 36480 ccaaaggatt tttaaatgtc aggatataat tctcagaatc caaaggagct caaagatgtc 36540 attctaagac gtttaggggc tccaattatt aatgttgagt taacacccga tcaaatctac 36600 gattgcatcc agcgtgccct agaattatac ggtgaatacc attttgatgg acttaacaaa 36660 ggttttcatg tattttatgt aggagatgac gaagaaaaat ataagaccgg agtcttcgat 36720 ttaagaggtt ccaacgtatt tgcagtaact cgtattttac gcacaaatgt tggatcaata 36780 acatctatgg acggtaacgc tacttatccg tggtttactg actttctttt aggaatggct 36840 ggtattaatg gtggtatggg aacgtcttgt aatagatttt atggaccaaa tgcctttgga 36900 gctgatttag gatattttac ccagcttacc agttacatgg gaatgatgca agatatgctt 36960 tcgcctattc cagacttttg gtttaattca gcaaatgaac aactcaaagt catgggaaac 37020 ttccaaaaat atgatttaat tatcgtagaa agctggacta aatcatatat tgatacaaac 37080 aaaatggttg gaaatacagt aggatatgga acagtcggtc cgcaagatag ttggtcatta 37140 tctgaacgat ataataatcc agaccataat ttagtaggtc gagttgtggg gcaagatcca 37200 gatgttaaac aaggcgctta taataaccgt tgggtgaaag actatgcaac agctttagct 37260 aaagaattaa atggccaaat tttagcacgc caccagggta tgatgcttcc tggcggtgtt 37320 acgattgatg gacaacgctt aatagaagaa gctcgattag aaaaagaagc actgcgcgaa 37380 gaattatact tacttgaccc tccatttgga atttttgtag gttaatatgg ctacttatga 37440 taaaaatctt tttgctaaat tggaaaacca cacaggttat tctcagacca atgaaactga 37500 aatattaaat ccttatgtaa atttcaatca ttataaaaac agccaaatat tagctgatgt 37560 attagtggct gaaagcattc aaatgcgagg tgtagaatgc tattatgttc caagagagta 37620 tgtttcccct gatttgatat tcggtgaaga cttgaaaaat aaatttacta aagcttggaa 37680 atttgccgcg tatctgaatt catttgaagg atatgaagga gctaaatcgt tctttggtaa 37740 ctttggtatg caagtacaag acgaagtgac tttatctatt aacccaaatt tatttaagca 37800 tcaagttaac ggaaaagaac cgaaagaagg cgatttgata tattttccta tggataacag 37860 cttattcgaa attaactggg ttgaaccata tgatccattt tatcaattag gccaaaacgc 37920 tattcgtaaa attacagcag gtaaattcat ttattctgga gaagaaatta atccggttct 37980 acagaaaaat gaaggaatta acattccgga attcagtgaa ttagaattaa atcctgttcg 38040 caatcttaat ggcattcatg atattaatat tgatcagtat gctgaagtag atcaaattaa 38100 ttctgaagct aaagaatatg ttgaacctta tgttgttgtc aataacagag gcaaatcttt 38160 tgaatctagc ccatttgata atgatttcat ggattaataa atattataaa ctaattaaag 38220 cccagattag gagaaatcat gtttggttat ttttataatt cgtcttttag acgatatgct 38280 accttgatgg gcgatttgtt ttcaaatatc caaatcaaac gtcagttaga atctggtgat 38340 aagtttatac gtgttcctat tacgtatgca tcaaaggaac acttcatgat gaaattaaat 38400 aaatggacat caataaattc acaagaagat gtagctaaag ttgaaactat tctacctcgt 38460 ataaatttac atttagttga ttttagctat aatgctccat ttaaaacaaa cattttaaat 38520 cagaatttac tgcaaaaagg tgcaacttct gtagtatcgc agtataatcc atctcctatt 38580 aaaatgattt atgaattgag tatatttact cgctatgagg atgatatgtt tcaaatagtt 38640 gaacagattc ttccatattt tcagcctcat tttaatacaa ctatgtacga acagtttgga 38700 aatgatattc catttaaaag ggatattaaa attgtattaa tgtctgctgc tatagacgaa 38760 gctatagatg gagataattt atctcgtcgt agaattgaat ggtcactaac atttgaagta 38820 aacggatgga tgtatcctcc agtagatgat gcagaaggat taattcgtac tacttataca 38880 gattttcacg ccaatacaag agatttgcct gatggcgaag gtgtttttga atctgtcgat 38940 aacgaagttg ttcctcgaga tattaaccca gaagactggg atggaacagt aaaacaaact 39000 ttcactagta atgtaaatag accaacaccg ccagaacctc ctggcccaag aacatagagg 39060 ttattatgga aggtcttgat ataaacaaac ttttagatat ttctgacctc cccggaattg 39120 acggggagga aattaaagta tatgaacctc tgcaattagt agaagttaaa agcaatcctc 39180 aaaaccgtac tccagactta gaagatgatt atggagtagt tcgtcgaaat atgcattttc 39240 aacaacaaat gctaatggac gcggccaaga tttttcttga gacggcaaag aatgctgatt 39300 ctcctcgtca catggaagta tttgcaactc ttatggggca aatgactacg acgaacagag 39360 aaatactgaa gcttcataaa gatatgaaag atattacatc tgagcaggtt ggcaccaaag 39420 gcgctgttcc tacaggtcaa atgaatattc agaatgcgac agtattcatg ggttcaccaa 39480 cagaattaat ggacgaaatt ggtgatgctt acgaggctca agaagctcgt gagaaggtga 39540 taaatggaac aaccgattaa tgcattaaat gatttccatc cgttaaatga agctggaaaa 39600 attttaataa aacacccaag cttagcggaa agaaaagatg aagatggaat tcactggata 39660 aaatctcagt gggatggaaa atggtatcct gaaaaattca gtgattacct tcgtctacac 39720 aaaatagtaa aaattccaaa caactctgat aagcctgaat tatttcaaac ttataaagat 39780 aagaataata aaagatctcg gtatatgggt cttcctaact tgaaacgagc taatattaaa 39840 acacaatgga ctcgtgaaat ggttgaggaa tggaaaaaat gccgagacga tattgtttat 39900 tttgcagaaa catactgtgc cattactcat attgactatg gtgtcataaa agttcaatta 39960 cgtgattatc agcgtgatat gctcaaaata atgtcatcta aacgtatgac tgtttgtaat 40020 ctatcgcgcc agctcggtaa aacaactgta gtagctattt tccttgcaca ctttgtatgt 40080 tttaacaagg ataaagctgt aggtattctt gcgcacaaag gctcaatgtc tgcggaagtt 40140 ttagaccgta ctaagcaagc aattgaactg cttcctgact ttttacagcc aggaattgtt 40200 gaatggaata aagggtctat tgaacttgat aatggttcct caatcggagc ctacgcttcc 40260 tctcctgacg cagttcgtgg taactcattc gcaatgattt acatcgatga gtgtgtagcc 40320 aaagatacta aagtaactat tagatgtaaa gctacaggcg aaataaaaga aatgactatg 40380 ctggaagtta aagcattggc aattacacaa aaagaggcaa aggatgcgca aaaataaaaa 40440 tggaaggcct atccagcgat taattatcgc ttcaagatat atttgccctg aatgcggtga 40500 atttaatgca aaatgtgcag gatatagatg caaaccttgc ggaagaaagg cccaaggtag 40560 agcaatgtct aatctgtata agaccaatca tgctgaaatg gtgaccaaat gcaataaacc 40620 ttatacagaa gatactagaa taaaacattc gaatacagtt aagaaaaaaa ttcttaacgg 40680 agaatttact ccaaagtcta ataatcgtag aacatggaaa cggatttaca aagatggcca 40740 tgcctttaga agttcatggg aattaaaatt ctatgattac tgtttaaata acaatatcaa 40800 agtagaatat gaagccctta gaattccata cgaatttgaa ggttccacac atatctatat 40860 tacggatttt attagtcata ccgagaaaaa agtatatgaa ataaaaccta attccatgat 40920 agatgaaaag gccctagcca aagaaaagta tgcaactaaa tggtgcaaag aaaacggtta 40980 tgaatatgtc tttattacgg aggacttctt atgcaatttt tagaattaga cggttatgaa 41040 gtcctcaccg acgacgggtt taaagacttc aatggtatta aatgcacttt cggacttata 41100 tggcgtactt gttttgatga tggaagccat ttagattcat cggacggaca tttaatcaaa 41160 atgaaaaatg gcaagtttaa aaaggccaaa aatattaaag ttggcgatat aacttctact 41220 ggtcttaaag taacttcatg tgatgaattt ttagaacaag atgagctgtt tgatttgaca 41280 aatgtagccg acggatatca ttataaaact aataatgtcg aatcacacaa ctgtgcattt 41340 attccaaatt tccatgattc ctggcttgct attcagccag taatttcatc tggtcgtcgt 41400 tcgaaaatta ttattactac gactcctaat ggattaaatc atttttatga tatttggact 41460 gcagccgttg aaggtaaatc tggatttgaa ccatacactg ctatttggaa ttcagttaaa 41520 gaacgtcttt ataacgatga agatattttt gacgatggat ggcaatggag tatacaaacc 41580 attaatggtt ccactttagc acaattccgt caagaacata ctgcagcgtt tgaagggact 41640 tctggtacat taatttcagg aatgaaatta gctgttatgg atttcattga agtaactcca 41700 gatgatcatg gttttcatcg atttaaaagc cctgaaccag atagaaaata tatcgcaact 41760 ctagactgct cagaaggtcg tgggcaagat taccacgctt tacatattat tgatgttacc 41820 gatgatgtgt gggaacaagt tggtgtttta cactcaaaca ctatttctca tttaattcta 41880 cctgacatcg ttatgcgtta tttagtagaa tataatgaat gcccagttta tattgaatta 41940 aatagtactg gtgtgtcagt tgctaaatcg ctttatatgg atttagaata cgaaggcgtt 42000 atttgcgatt catatactga tttaggaatg aagcaaacta aacgcacgaa agcagtagga 42060 tgctctacat taaaagacct tattgaaaaa gataagctta ttattcatca ccgtgcaact 42120 attcaagagt ttagaacgtt tagtgaaaaa ggtgtgtctt gggcggctta agaaggttat 42180 catgacgatt tagtaatgtc tttagtgatt tttggatggt tatcaacaca gtcaaaattt 42240 attgattatg cggataaaga tgacatgcga ttagcatctg aagtgttttc aaaagaactt 42300 caagatatgg gtgatgaata cgcgccagtt atatttgtgg attcggttca ttctgctgag 42360 tatgttccag tatctcatgg tatgtcaatg gtataaatat attaaagcat attaaagagg 42420 attaaaaatg actttattat ctccgggcat tgagctcaaa gaaactacgg ttcaaagcac 42480 cgttgttaat aactctactg gtacagcagc tttggccggt aaattccagt ggggtcctgc 42540 ttttcagatt aaacaggtta caaatgaagt agatttagtt aatacttttg gtcaaccaac 42600 cgctgaaact gctgactatt ttatgtctgc gatgaatttc ttgcagtacg gaaatgactt 42660 acgagtagtt cgtgctgttg atagagatac cgctaaaaac tcatctccga ttgctggtaa 42720 tattgaatac acaatttcta ccccaggtag taactatgca gttggagata aaatcacggt 42780 caaatatgtt tcagatgata ttgaaactga aggtaaaatt accgaagtag acgcagatgg 42840 aaaaattaag aaaattaata ttcctactgc aaaaattatt gctaaagcta aagaagttgg 42900 cgaataccca acattaggtt ctaactggac tgcagaaatt tcttcatctt cctctggttt 42960 agctgcagta ataactcttg gaaaaattat tactgattct ggtattttat tagctgaaat 43020 tgaaaatgct gaagctgcta tgacagaggc tggctttcaa gcaaatctcg aaaaatacgg 43080 aattccagga gtagtagctc tttatccagg cgaattaggc gataaaattg aaattgaaat 43140 cgtatctaaa gctgactatg caaaaggagc ttctgcatta ctcccaattt atccgggcgg 43200 tggtactcgt gcatctactg ctaaagctgt gtttggatat ggaccacaaa ctgattcaca 43260 gtacgctatt atagttcgtc gcaatgatgc tattgttcaa agtgttgttc tttcaactaa 43320 gcgtggtgaa aaagatattt acgatagtaa catctatatc gatgactttt tcgcaaaagg 43380 tggttcagaa tatatttttg caactgcaca aaactggcca gaaggcttct ctggaatttt 43440 aactctgtct ggtggattat catcaaatgc tgaagtatca gcaggagatt tgatggaagc 43500 ttgggacttc tttgctgacc gtgaatccgt tgatgttcag ctgtttattg cgggttcttg 43560 tgccggtgaa tctttagaaa cagcatctac tgtccaaaaa cacgtcgttt caattgggga 43620 tgctcgccaa gattgcttag tattgtgctc tcctccacgt gaaactgtag ttggaattcc 43680 tgtaactcgt gcagtagata atttagttaa ctggagaact gcagcaggtt catacactga 43740 taataacttt aatatcagtt caacctatgc agcaattgat ggtaactaca aatatcagta 43800 tgacaaatat aatgatgtga atcgttgggt tccattagca gctgatattg ctggtttatg 43860 cgcaagaact gataacgtat ctcagacttg gatgtctcca gctggttata atcgtggtca 43920 gattcttaac gttattaaac ttgctattga aactcgccag gctcagcgcg accgtttata 43980 ccaagaagct atcaacccag taactggtac aggtggcgat ggttatgtat tgtatggtga 44040 taaaacagct acttctgttc cttctccatt tgatcgtatt aacgttcgtc gtctgtttaa 44100 tatgttgaaa acgaatatcg gacgtagttc aaaatatcgt ttgttcgaat taaacaacgc 44160 gtttactcgt tcatcattcc gcacagaaac tgcccagtac ttgcagggaa ttaaagctct 44220 cggtggaatt tatgaatatc gtgtagtttg cgatacaaca aataacactc cgtcagtaat 44280 tgatagaaat gagtttgttg caacattcta catccaaccg gcgcgcagta taaattatat 44340 ccaacttaat ttcgtcgcaa cggctactgg tgcagatttc gatgagttaa ctggtcttgc 44400 tggttaatac ggtgcattct aaaggcctgt ttcggcaggc catataaata cactatatcc 44460 ttaattcttt aattctatat gccctaggtt aaacataggg atataaatac tacagaggct 44520 aatatgtttg tagatgatgt aacacgagcg tttgaatctg gtgattttgc tcgacctaac 44580 ttattccaag tagaaatttc ttatcttgga caaaatttta cgtttcaatg taaagccact 44640 gctttaccag ctggtattgt agaaaaaatt ccagtcggat ttatgaaccg taaaattaac 44700 gtagcaggcg atcgtacatt cgatgactgg actgttacag taatgaacga tgaagctcat 44760 gatgctcgcc agaagttcgt tgattggcaa agcattgctg cggggcaagg aaacgaaatt 44820 actggtggaa aacctgcaga gtataaaaag agcgctatcg ttcgtcaata tgctcgtgac 44880 gctaaaacag taacaaaaga aattgaaatt aaaggtctgt ggcctactaa cgtgggtgaa 44940 cttcaattag attgggattc aaacaatgaa atccaaacat ttgaagtaac tcttgctctc 45000 gattattggg aataaaatga atggggagaa atccccatcc tgcttaaagc agagaagtcc 45060 attataaata taactataat tcccatttgg agaatacaat gaaatttaat gtattaagtt 45120 tgtttgctcc atgggctaaa atggacgaac gaaattttaa agaccaagaa aaagaagatc 45180 ttgtttccat tacagcccca aagcttgatg atggagcaag agaatttgaa gtaagcgcaa 45240 atgaagctgc ttctccttat aatgctgcat tccaaacaat ttttggttc tatgaaccag 45300 gaatgaaaac tactcgtgag cttattgata catatcgtaa tctcatgaat aactatgaag 45360 tagataatgc agtttcagaa atcgtttcag acgctatcgt ctacgaagat gatactgaag 45420 tcgtagcgtt aaatttggat aaatctaaat ttagcccaaa aattaaaaat atgatgttag 45480 atgaatttag tgatatatta aatcatctat cgtttcaacg aaaaggttct gatcatttta 45540 gacgttggta tgttgattca agaattttct ttcataaaat cattgatcca aaacgtccaa 45600 aagaaggcat aaaagaatta cgtagattag atcctcgcca agttcagtat gttcgtgaaa 45660 ttataacaga aactgaagct ggcacaaaaa tagttaaagg ttacaaagaa tattttatat 45720 atgatactgc ccatgagtca tatgcatgtg atggtagaat gtatgaagct ggcacaaaaa 45780 taaaaattcc taaagctgcc gtagtttatg cccattctgg attagtcgat tgttgcggta 45840 aaaatatcat cgggtattta catcgtgctg ttaaacctgc taaccaatta aaattattag 45900 aagatgctgt agtcatttat cgcattactc gtgctcctga ccgccgtgtt tggtatgtag 45960 acacaggtaa tatgcctgct cgtaaagctg ctgagcacat gcaacatgtc atgaacacga 46020 tgaaaaaccg tgtagtatat gatgcatcaa ccggtaaaat aaaaaatcaa cagcataata 46080 tgtctatgac cgaagactat tggttgcagc gccgtgacgg taaagctgtg acagaagttg 46140 atactcttcc tggtgctgat aatactggca atatggaaga tattcgttgg tttagacaag 46200 ctctttatat ggcattacgt gttcctcttt cacgcattcc gcaagaccaa caaggcggtg 46260 tgatgtttga ttctggaact agcattacac gtgatgaatt aacgtttgct aaatttattc 46320 gtgagttgca gcacaagttt gaagaagttt tcctagatcc gcttaaaaca aatcttttgc 46380 ttaaaggtat aatcacagaa gatgagtgga atgatgaaat aaataatatt aagatagaat 46440 ttcatcggga tagctacttt gctgagctca aagaagcaga aattttggaa cgaagaatta 46500 atatgctaac catggcagaa ccatttattg gtaaatatat ttctcacaga actgctatga 46560 aagatatttt gcagatgact gatgaagaaa tagaacaaga agccaagcaa attgaagaag 46620 agtctaaaga ggctcgtttc caagaccccg accaagaaca agaggatttt taatggaagg 46680 tttaattgaa gctattaaat caaacgacct cgtagccgct cgtaaattat ttgctgaagc 46740 catggctgca agaacgattg atttaattaa agaagaaaaa atcgctatcg ctcgtaattt 46800 cttaatcgaa ggtgaagaac ctgaagacga ggatgatgac gaagacgaag atagtgatga 46860 taaagacgac aaaaaagaca aagactctga cgaagacgag gatgatgaat aatgcttctg 46920 atccctgaaa ctcatgaatt agttctcgag aatgtcgaag cacttattcc tgaagcacag 46980 ggtcgctttg acgaattgtc ttctgcttta aataaagacg atataaatac agttgtcgag 47040 aatatgcttg atgatgaaac tgatttagcg gttgcattag cttctattaa tgaaaatatg 47100 ccgttaaatg aatttatcgt taaacatgtt tccgcccgtg gtgaaattac tcgcactaaa 47160 gatcgcaaaa cccgcgaacg aaatgcattt caaaccactg ggctgtctaa agcaaaacgt 47220 agacaaattg ctcgtaaagc taccaaaacg aagattgcca atccagcagg tcaatctcgt 47280 gctcagcgta agcgtaaaaa agctcttaaa cgccgtaaag cattaggatt aagctaatga 47340 atgaacccca attactaatt gaaacttggg gtcaacctgg cgaaattatt gatggcgtac 47400 caatgcttga atctcatgat ggaaaagact taggtttaaa acctggttta tacatcgaag 47460 gaatattcat gcaagcggaa gtcgtcaata gaaataaacg tctttatcca aaacgtatat 47520 tagaaaaagc ggtaaaagac tatattaatg agcaagtttt aactaaacaa gctctcggag 47580 aattaaatca tcctccacgc gctaatgttg acccgatgca agccgctatc attatagaag 47640 atatgtggtg gaaaggaaat gacgtatacg gacgagctcg tgttattgaa ggtgaccatg 47700 gtcctggaga taaattagca gctaatattc gtgccggatg gattccagga gtttcttctc 47760 gtggattagg ttcattgact gacacaaata aaggttatcg tatcgtaaac gaaggattca 47820 aattaactgt aggtgttgat gcggtatggg gtccaagtgc tccagatgca tgggtaactc 47880 ctaaggaaat taccgaatca cagacggcgg aagccgatac aagtgccgat gacgcctata 47940 tggctctcgc agaggccatg aaaaaagcgt tataaatatt attatctaaa caacaggact 48000 acaaaatgct taaagaacaa ctgattgctg aagcgcaaaa aattgatgct tccgttgctc 48060 ttgatagtat tttcgaatca gttaatattt ctccggaagc aaaagaaact ttcggcactg 48120 tattcgaagc taccgtcaag cagcacgccg ttaaattagc tgaatctcat atcgctaaaa 48180 ttgctgaaaa agcagaagaa gaagtagaaa aaaataaaga agaagccgaa gaaaaagctg 48240 agaagaaaat cgctgagcaa gcttctaaat tcattgacca tcttgcaaaa gaatggctcg 48300 ctgaaaataa attagcagtt gataaaggca tcaaagccga actgtttgaa tccatgcttg 48360 gtggattaaa agagctcttt gttgaacaca acgttgttgt tccagaagaa tcagttgata 48420 ttgtagctga aatggaagaa gagctgcaag aacataaaga agaatcagct cgtctgttcg 48480 aagaactcag catgcgcgac gcatatatca attatgtgca gcgtgaagtg gcattgagcg 48540 aaagtactaa agatctgact gagtctcaaa aagaaaaagt ctctgctctg gtcgaaggta 48600 tggattattc agatgcattc tcaagtaaat tgagtgcaat cgtagaaatg gtgaagaaat 48660 ctaataaaga tgaaagcact attactgaga gtataaatac tcctgatact gaagcagccg 48720 gactgaattt cgtcactgaa gctgtagaag ataaagctgc acagggtgca gaagatattg 48780 taagtgtata tgcgaaagtc gcatctcgtt tctaatttta aaggttaaca caaatgacta 48840 tcaaaactaa agctgaactt ttgaacaaat ggaagccatt actggaaggt gaaggtttac 48900 cggaaattgc taatagcaaa caagcgatta tcgctaaaat ctttgaaaac caggaaaaag 48960 atttccagac agctccggaa tataaagacg aaaaaattgc tcaggcattc ggttctttct 49020 taacagaagc tgaaatcggt ggtgaccacg gttacaatgc taccaacatc gctgcaggtc 49080 agacttctgg cgcagtaact cagattggcc cagctgttat gggtatggta cgtcgtgcta 49140 ttcctaacct gattgctttc gatatttgcg gtgttcagcc gatgaacagc ccgactggcc 49200 aggtattcgc aatgcgcgca gtatacggta aagacccaat cgcttccggt gctaaagaag 49260 cattccaccc aatgtatggt ccagatgcaa tgttctctgg tcagggtgct gctaagaaat 49320 tcccagctct ggctgttaat actactacag ttgtaggtga tatctatact cacttcttcc 49380 aggacactgg tactgtgtat ctgcaagctt ccgctgtagt aacaattagt tcaagcgcaa 49440 ctgatgcaga taaattagat gctgaaatta agaaacaaat ggaagctggt gcactggtag 49500 aaatcgctga aggtatggct acttctatcg ctgaacttca ggaaggtttc aacggttcta 49560 ccgataaccc atggaatgaa atgggcttcc gtatcgataa acaagttatc gaagctaaat 49620 ctcgccagct gaaagctgct tactctatcg aattagcaca agacctccgc gctgttcacg 49680 gtatggatgc tgatgctgaa ctgtctggta ttctggctac agaaatcatg ctggaaatca 49740 accgtgaagt tgttgattgg attaactact cagctcaggt tggtaaatct ggtatgaccc 49800 tgactccggg ttctaaagct ggtgtatttg acttccagga cccaatcgat attcgtggtg 49860 ctcgctgggc aggtgaatcc tttaaagctc tgttgttcca gattgacaaa gaagcagttg 49920 aaattgctcg tcagaccggt cgtggtgaag gtaacttcat tatcgcttcc cgtaacgtag 49980 ttaacgttct ggcttcagtt gatactggca tttcttatgc tgcacagggt ctggctaccg 50040 gctttaacac tgatactacc aagtcagtat ttgctggtgt tctgggtggt aaataccgtg 50100 tatatatcga ccagtatgct aaacaggatt atttcactgt aggttataaa ggtccgaacg 50160 aaatggatgc tggtatttac tatgctccat atgtagctct gactccgctg cgtggttccg 50220 atccgaagaa cttccaaccg gtaatgggat tcaaaactcg ttacggtatc ggtatcaacc 50280 catttgcaga atccgctgct caggctccgg cttctcgcat ccagagcggt atgccttcta 50340 ttctgaatag ccttggtaaa aacgcttact tccgccgtgt atatgttaaa ggtatctaat 50400 ctttgacgat ttaagggacc ttcgggtccc tttagttgtt tttatggtat aaataaatca 50460 tataaactga aaggaaagcg caatggctaa aatcaacgaa cttctgcgcg aatcaaccac 50520 aacgaatagc aactcaatcg gtcgcccaaa tctcgttgct ttgactcgcg ctaccactaa 50580 attaatatat tctgacattg tagcaacgca aagaactaat caacctgttg ctgcttttta 50640 tggtatcaaa taccttaacc cagataacga atttacgttt aaaactggtg ctacttacgc 50700 tggcgaagct gggtatgtag accgagaaca aatcacagaa ttaacagaag agtctaaatt 50760 aactctcaat aaaggcgatt tattcaaata taataatatc gtttataaag tgttagaaga 50820 tacaccattt gcagatattc aagaaagcga cttagagtta gctcttcaga ttgcaatcgt 50880 tcttttaaag gttcgtctat tttctgacgc agcgtcaaca agcaaatttg aaagctctga 50940 tagtgaaatt gcggatgcta gattccagat taataaatgg caaaccgcgg ttaaatctcg 51000 taaacttaaa actggcatca cagttgaatt agcgcaagat ttagaagcaa atggattcga 51060 tgctcctaat ttcttggaag atttgcttgc aactgaaatg gcagatgaaa tcaataaaga 51120 tattctgcag tctttgatta cagtatcaaa acgttataaa gttacaggaa ttactgatac 51180 tggattcatt gatttgagtt atgcatctgc acctgaagct ggtcgttcat tataccgaat 51240 ggtatgtgaa atggtttcgc atatccaaaa agaatcaact tatacagcaa cgttctgtgt 51300 tgcttcagct cgtgctgctg cgattcttgc tgcatcaggt tggttaaaac ataaaccaga 51360 agatgataaa tatctttcac aaaatgccta cgggttctta gctaatggtt taccgcttta 51420 ttgcgatact aacagcccat tagattatgt aatcgttggt gtagtagaaa atattggcga 51480 aaaagaaatt gttgggtcaa ttttctatgc tccgtataca gaaggtcttg acttagatga 51540 ccctgaacat gtaggtgcat ttaaagttgt agttgaccca gaaagtttgc aaccatctat 51600 cggtttattg gttagatatg ctttatctgc aaatccttac actgtagcaa aagatgaaaa 51660 agaagcaaga ataattgatg gtggagacat ggataaaatg gcgggtcgtt cagatttgtc 51720 tgttttatta ggtgttaagc taccaaaaat tatcgttgat gaataaaaca aagggacctt 51780 tcggtccctt tttatttagc tcaccaactc aatccaagcc ggacgaagta catcttgtac 51840 cattttaact aattcctttt taatcaaaga aggattatcc gcttgagtta gagtaatacc 51900 ttcacgagaa gtttcttcca aaatatcttg aacagttagt cccatcacct ttccaaaatc 51960 ttttggacca atttcgccaa ttttagaaat aacgttattt actcggttca gtgtaacgta 52020 acaagctaaa atccccacca atttgttatc agcttctgac agttcaactt taactttaat 52080 aggcttatca gactttttct tttcactaaa tttggaattc ttgcatttga tggctacacg 52140 atttccatta tgaagccaag aaggataaca aggtttcaat acataacctt cagcggtaaa 52200 tacttcgcct ttggcttcgg cattccagac gcatttattt gcatcaacta atccagcatg 52260 gtctactgta aaattataat cttgaacgac agagtctaaa tcatttggca atttaataag 52320 ttcttcaaat ttaccacgac ccaaaagtgg agccatttta aatttgaatg tattacagaa 52380 tgattccatc atataatcat cgacataagt cacatcacca ctttcggtag taacaataat 52440 gtcaaataca taaaaatctt tatcgccata atcgacattc ttctgaatgc caggtccagc 52500 aaattcacca aagacttgat aagatacaac tgctgaagtt tccataatat cttgtactgc 52560 tttaatggaa tcagcgtaat tctttagaat aatttcatac ccaaagaaat cttcagcagg 52620 aagaatcggt ccagtacgtt tagcacaagt tgctttatcg cgctcaataa tcaacgagaa 52680 atttgtacca tgaatctttt cacgagctac ccattcgcca ccagtcaatc ctaaactgta 52740 aagtttttca ataaatttag aattgtaatg attttcaaga ctgctatact ttttaaacat 52800 aattaatcct caaaatgtaa tttctaacca atcaccatca cgctgatcac tattgacttt 52860 aaaactgaat ccttcttttc tcagccaatc accaatttct tcagtaatca atttatcacg 52920 agcaatacaa taataactaa aatgtgtttt accttgctca gctgctttat tagcaagttc 52980 cgaaaaatct ttaataaaac actctagttt aaactgttta cttttaagtg ctttttcgcg 53040 taattgatta gcaaaagatt cattttcata aagatcatac tgttccattt ttcacctttt 53100 tattaatatg tctttttcta tagacaactt tttctcgagt ctcaaattta ttcttagcag 53160 tcatagctcg agcccataat acagccacgt cttttgcctg taagtttaat tcacgagcaa 53220 tttcaatgaa tgactttcca gactcatgaa gagtaaacac cacaacctca gttctcataa 53280 tcaatctcat gttatcgagt tggtgccatt atatacatca ttttctgatt gtgttttgtg 53340 tgctttcaaa atgaagaaag gggccgaagc cccttatgat tatggatagg tatagatgat 53400 accagtttct aaagcagttt tatgaatgat gtatccatta cgcgattctt ggacatcaac 53460 ttctggatag tctttcatca tcttctgaag agtgtaacga tgcaagtagt acttactatc 53520 tggatcgtca gttttccaat ctttaccttc ttcggtcatt ttttggattt catccataac 53580 ccaccaaccg caccagatgt aagctgaagt acgatgtgga agaggatgaa cataaggtaa 53640 ttcaccttta ggagcaggag ctactttagc cgtgactgtt acattaccag ttttggtaac 53700 ggttacaggg ttataatctg cagcagatac aacaacagaa acgccaatca cttgggaccc 53760 tatatcagac gtgtcaatcg ctaaagtgct agtagaacct tctacaggag aaccatcttt 53820 ggtccaagaa taaaccccag ttgcacctcc cggagcaccg ataacgttgg ctttaaaaga 53880 tgcctcagaa ccttgttcag tcataataga ctcaggagtc agagtaactg aaactccgct 53940 catagtcttt ttggtaatag ttacattacc ggttttagta actgtaaccg acttataatc 54000 tggggcagaa acaacagccg aaacctcaat tacctgtgac ccgatagtag atgtatcaac 54060 ttctagagta tttgttgagc catcaacagg agacccgtct ttggtccatg aataagctac 54120 agatgctcct gccggcgctc cagtaacatc ggctttaaaa gatgcttctg ctcctttttc 54180 agcggtaatt gaactaggcg tcagagtaac agaaacggct cccatagtct ttttagtaaa 54240 aacaacctca ataccgttag tcgcagtagc tgggttataa tttgatgcag aaactgtaac 54300 ttcacaattc aatgtgtaat tagcttctgc gggttcagtt atggtaattg ttttagcagt 54360 ctgaccttca ataacgacaga taccacgttt ccaaacacata gcaatgcttg caccttctgg 54420 agcaccaaca acgttagctg taactacctg agactgccca atctctttgg aaacagaagt 54480 cgggctcaag gttaaagtaa tcgcaggcat agttttgttc tgaacggtca gagtggtttc 54540 tgcctcagca gtttctgccg caccctctgc tggggtaaca gtagcaacta ctttaacagt 54600 cttactacct gcaggtcctg cagcaacata attcatagct gcggtgacag aagattgttt 54660 tacgccgttt actgtccaca caaacgtttc tgtgccttca gctgcggcac cagaagttgt 54720 tgcagtaaaa ttggttgttg ctccaatgac tgccgaagca gccaaaggag caatagatac 54780 gctataagcc ataggtgttc cttattttaa tgttacgaaa gaagagttgc gtgtttcacg 54840 aattaaaact gatccgtcac ggttaatgta ataaattaag ctaaataaag tttggtgtgc 54900 cgacgcgtgt tcaaaactag ttgggtgaga tttccaatcc ggagtttcag caatccattg 54960 ataaatccac caaggaacag tgcagaatcc tggatttttt ccaatcaact gaagattcgg 55020 actaaagttt tccggaagag taaatacaga cggcttttca gattcaataa tctcagctac 55080 agcttgttcg aatttttctt caacaaaagg agtatcttca attaaaacat cggtattttc 55140 aggaatttta tccgtttcta ctacttcaat tttaatgtca gatttaaccg gagaatcaat 55200 cgaagtgct gcttctggat tgacttcttc atcgtcatat tttaacccct ctgcagcatc 55260 agcagcattg attaagtctt taatagataa cccatcagtc tctggcatag gttcactagc 55320 gagcttctgg agggcttctt caatatcatt aacgatatta tcaaaagatt tattcttttt 55380 gacctttata ccaaactgtt cagcatattc agctaattta gccttagctt ctttattatc 55440 atcaagagcc ttcagctctg caatataatc tttatctatc ataatatttc ctcagtataa 55500 atatagatat atttattaca tggtatttag acatgactga cattaaagta catttttatg 55560 attttagtca cgtgagaatt gattgtgaag aaagtacatt tcatgaactc cgtgatttct 55620 ttagctttga agctgatggg tatcgtttta atccgaagta cagatatggc cactgggatg 55680 gacgaatccg tcttttagat tataatcgtc ttcttccatt cggcttagtc gggcaaatta 55740 aaaagttctg tgataacttt ggctataaag cttggattga cccgcaaatt aacgaaaaag 55800 aagaattatc aagaaaagat tttgatgaat ggctttctaa gttagaaatc tattcaggaa 55860 ataaaagaat tgaaccgcat tggtatcaaa aagatgcagt gttcgaagga ttagttaatc 55920 gtcgtagaat tcttaatctt ccaacatccg ctggtaaatc tttaattcaa gctttgcttg 55980 cacgttatta tttggaaaat tatgaaggta aaattcttat cattgttcca acaactgctt 56040 taacaactca gatggctgat gactttgttg actatcgttt attcagtcat gcaatgataa 56100 agaaaatcgg tggtggagca tcaaaagatg ataaatataa aaatgatgca ccggtaattg 56160 ttggtacatg gcaaactgta gtaaaacaac caaaagaatg gttttcccaa tttggtatga 56220 tgatgaatga tgaatgccat cttgctacag gaaaaagtat ttcatccatc atatcaggtt 56280 taaataactg catgttcaaa ttcggtttgt ctggttcatt acgtgatggc aaagccaata 56340 tcatgcagta cgttggaatg tttggtgaaa tatttaagcc agtaacgact tctaaattaa 56400 tggaagatgg gcaagtaact gagttaaaaa ttaatagtat ttttcttcgc tatcccgatg 56460 agttcactac taaattaaag ggaaaaactt accaagaaga aataaaaatt attactgggc 56520 tcagtaaaag aaataaatgg atcgctaaat tagctattaa gcttgcgcaa aaagatgaaa 56580 acgcttttgt catgtttaaa catgtatcgc acggtaaagc tattttcgat ttaattaaaa 56640 atgaatacga taaagtttat tacgtatcag gggaagttga taccgaaacc cgcaacgtaa 56700 tgaaaacctt agctgaaaat ggtaaaggaa taattatagt agctagttat ggtgtatttt 56760 ctactggtat ttcagttaaa aatctgcatc acgttgtttt agcgcacggt gttaaatcaa 56820 aaatcattgt attacaaaca atcggtcgtg tattacgtaa gcatggttct aaaacaatcg 56880 caacggtctg ggacctcata gatgacgcgg gcgtcaagcc aaaatctgct aatacgaaaa 56940 agaaatatgt tcatttgaac tatcttttaa aacacggcat tgatcgtatt cagcgctacg 57000 cagatgaaaa atttaattac gtaatgaaaa cagttaattt ataagggctt cggccctttg 57060 gagaaaaaga tgttactagg atttaaacaa tttctttatg aagcttctat tgatgaattt 57120 atgggtaaaa ttgcctcttg tcaaacatta gaaggtctag aagaacttga agcttattat 57180 aagaaaagag ttaaagaaac tgaattaaaa gatactgatg acatctctgt gagagatgct 57240 ttggcaggaa aaagagctga attagaagat tcagacgatg aagtagaaga aagcttttaa 57300 attaaaaaag gcccaaccaa aaaggaaggg ccaaaactat agactaaagg tcacactata 57360 gcaaaagttg tgtttcattt aattgttctt ccgaactttc tgaaactggt agttctttaa 57420 tgtaattata gcaaggccca ggatgtacag gacctttgtc tgtttcaaca accaatgcag 57480 aatcgattgg agttttacag acaacacaaa tcttatctga catgattgtc tccttttgaa 57540 tatagtaata tttataaacc cattttaatc cgcatttctt gtacacggat taagcaagct 57600 tccatctctg ctaatagtcg aaatacttct ttataatctg tcatatttac cccatatctc 57660 tcatatgcat atcaatgccc atatctttag aataaaaata ttcatcaaga tatccggcaa 57720 attttccttt aatataaagg acatcttcac cacacgggtg gtcggccagg atacgaatat 57780 cctgacgctt aagattatgc tttttcatta agaattgaat ctcagtttca aattcttctt 57840 cataattaaa agcatcatca atgctatatc tcattatttt ccagcctcaa atgcccgcat 57900 gtcttgaata tgcttaatag caaatcctcg tgatttgata gcatcaagag ctccactaca 57960 gaaatctaat aaaatccccc aatactgcag cgaggtatca acctttaaaa catccttatc 58020 agctgataga actgtcttca tttctgattt ctcgtaacga tccatactaa attcatcacc 58080 atctcctcgt cccgagtagt agtctaatct agctttaaga gcaacttttt tctgtgcgtc 58140 aattctaagc atttcctttt taatacttga atgcttatta agccatttac tatataacat 58200 cacattatta gctgcttcat actgtaattt agtcgaatct ataaacacat ctttcttcaa 58260 ttcttcttga agatcttcta atctcatatt gttctctatt caattgttat tggatggact 58320 tagattcatt ataccacgtt ttaacgtgaa gcattatacc ctattactcg aagccagttg 58380 cagttttatc tgctcaatat catcagggtt atcgatgacc gaaaagcgta tttctactat 58440 cagagtataa tcatcataaa ctggtatcac attaactgat aatttatcaa tacgtggctc 58500 atagtttctt actgcgcttt cgatattgcg ctcaactgtg tcagcagtaa gaggagtcat 58560 attttcaaaa agctggtctg ataaatcaca tccaaattca gggtcaaacg gtcttgaacc 58620 ttttcttgtt gtaataattc ccaaaagact gtttttaatt gaccttaatc caagtgatct 58680 ggaaacatct ttgttccaat ccattttcat ttccgggtca atatcagaat aaagcttatt 58740 aatatttgcc attatagtaa ctcaaagaac tctttgaggc ctcttattac atgagcatgg 58800 gtttttccac actctggaca tttaattgga acagccaaat aaacggtagg ttttaaaagc 58860 atatctttta tagctacaat atctgactct gtgatgatag aatataaatc ttctagttcc 58920 ttttcattta agtcttcaac tggaatgctt tccccgttag catgaatcgt ttctatgcat 58980 gatactatca tgtgggctat atttttatca tcaaaaattt tagggtatcg gaatttaatt 59040 ttaatgtcac ccagtgtata ccagaggtct tctggtgcat ctatttgtgt atgtaataga 59100 tttatatggg ttggtatttc agttccacag gtgcacttcc aggagttttc gtgattaact 59160 tcaccgagag aatgtgccca taaatgaatc agcagtagtt ctgattcttg gcggtttaaa 59220 tcttttgcat ttgtgcagtc tttgattagc tttttaacaa ttacttctac agaaccatta 59280 tttttggcag taataagttc tagatattct ttaagcgtga atgcgcgaca attgattatt 59340 ttagaaccaa ctctcacatc aaatttgtat tcatacatat ttagctcctt tatttatcat 59400 atttataaat agaataaaag gagcatctat ggcaaacatt attcgttgta aattaccaga 59460 tggtgttcat cgttttaaac catttacggt agaagattat cgagattttt tgttagttcg 59520 aaacgatata gaacatcggt caccacaaga acaaaaagaa gtaattgctg atttaattgc 59580 tgattatttt ggagactatc cgaagacttg gcaaccattt atatttttgc aggtatttgt 59640 aggatcgata ggtaaaacta aagtaccggt cacatttgta tgtccaaaat gtaaaaaaga 59700 aaagacagtt ccatttgaaa tatatcaaaa agaattaaag gaacctgttt ttgatgtagc 59760 taatgttaaa attaaattaa agtttccttc tgagttttat gaaaataaag caaagatgat 59820 tactgaaaat attcattctg ttcaagtaga tgaaatatgg tatgattgga aggaaattag 59880 tgaatcaagt caaatagaac ttgttgacgc catcgagata gaaacattag aaaaaattct 59940 cgatgtaatg aatcctatta atttaactct acatatgtca tgctgtaata agtacattaa 60000 aaaatacact gatatagtag acgtgtttaa gctattagtt aatccagatg agatatttac 60060 tttttatcaa attaatcaca cactagtaaa aagtaattat agtttaaatt caataatgaa 60120 aatgattcct gctgagcgcg gattcgtatt aaaactgatt gagaaggata aacaataatg 60180 agtatgttgc aacgcccagg atatccaaat ctcagcgtta aattgtttga tagctatgac 60240 gcttggagta ataatagatt tgttgaatta gctgctacta ttaccacatt aactatgcgg 60300 gattctcttt atggccgaaa tgaaggaatg ctgcagtttt atgattctaa aaacatccat 60360 acaaaaatgg atggaaatga aataattcag atttctgtag ctaatgcaaa tgatattaat 60420 aatgttaaaa cacgaattta tggatgtaag catttttccg tgtcagtaga ttcaaaaggt 60480 gataacatca ttgctattga attgggaact attcattcta tagaaaatct taaatttggt 60540 agaccatttt tccctgatgc aggtgaatct ataaaggaaa tgcttggcgt catttatcag 60600 gatcgcacat tattaactcc agcaataaat gctataaatg cttatgttcc tgatattcca 60660 tggactagca catttgaaaa ctatttgtca tatgtaagag aagttgctct agctgtagga 60720 agtgacaaat ttgtatttgt gtggcaagac atcatgggag ttaacatgat ggactatgat 60780 atgatgataa atcaagaacc atatccaatg attgtcggtg agccatcttt aataggtcaa 60840 ttcatccaag aattaaaata tccattagca tatgatttcg tttggttgac taaatcgaat 60900 cctcataaac gcgacccaat gaaaaacgct actatctatg ctcattcatt tttagattct 60960 tcattgccaa tgattactac aggaaaggga gaaaactcta ttgtagtgtc aaggtcaggt 61020 gcttattctg aaatgactta taggaatgga tatgaagaag ctattcgtct tcaaactatg 61080 gcgcaatacg atggctatgc taaatgttct actgtcggta attttaactt gacacctggc 61140 gttaaaatta tttttaatga tagtaaaaac caatttaaaa cagaatttta cgttgatgaa 61200 gttatccatg aattatccaa taataattca gtaactcatc tatatatgtt cactaatgca 61260 acgaaactgg aaacaataga cccagttaag gttaaaaatg aatttaaatc tgatactacc 61320 actgaagaaa gtagttcttc caataagcaa taaagaagtt tctattccta aaatgggtct 61380 taaacattat aacattttaa aggatgttaa aggtcctgat gaaaatttaa aacttcttat 61440 tgattctatt tgtccgaatt tatcaccggc agaagttgat ttcgtttcta ttcatttatt 61500 ggaatttaat ggaaagatta aatctcgtaa agaaatagat ggctatactt atgacattaa 61560 cgatgtttat gtgtgccaaa gattagaatt tcaatatcaa ggaaatacat tttattttag 61620 acctcctgga aaatttgaac aatttttaac ggtgagcgat atgttatcta aatgcttgct 61680 taaggtcaat gatgaagtta aagaaattaa ttttcttgag atgccagcat tcgttttaaa 61740 atgggcaaat gatattttta caactttagc aattcctggc cctaatggtc caataactgg 61800 aattggcaat attattggat tatttgaatg aaaaagccac aagaaatgca aacgatgcgt 61860 agaaaagtta tttcagataa taaaccaaca caggaagcgg ctaaatccgc ttccaacact 61920 ttatctggac ttaatgatat atctacgaaa ttggatgatg ctcaagctgc ttctgaacta 61980 attgctcaaa ctgtcgaaga aaaatcgaat gaaataattg gagcaattga taacgtagaa 62040 agcgcagtga gtgatactac tgccggttct gagttaattg ctgaaactgt cgaaattggc 62100 aacaatatta ataaagaaat tggtgaatca ctcgggagca aattagataa attaacaagt 62160 ttactagagc aaaaaattca gacagctgga attcaacaaa caggaactag tttagctacg 62220 gttgaaagcg ctattcccgt taaagtcgtt gaggatgata ctgctgaatc tgtgggtcct 62280 ttattaccag ctcctgaagc agttaataat gatcctgacg ctgatttttt ccctacccct 62340 cagccagttg agccaaagca agaatcacca gaagaaaaac agaaaaaaga agcatttaac 62400 ttaaaattat ctcaagcttt agataaatta acgaagactg ttgattttgg atttaagaaa 62460 tccatttcaa ttactgataa aatatcaagc atgctattta agtataccgt cagtgctgct 62520 attgaagctg ctaaaatgac tgcaatgata ttggctgttg ttgttggaat agacctgttg 62580 atggttcact ttaaatattg gtcagataaa ttttcgcagg cttgggattt gtttagtaca 62640 gactttacta aattctctag cgaaaccgga acatggggtc ctttattaca gagcatcttt 62700 agttctattg atgaaattaa aaagttctgg gaagcgggag attggggtgg attgacagta 62760 gctattgttg aagggcttgg aaaggttctt tataatttag gagaacttat tcaattaggt 62820 atggctaaat tatctgctgc aattcttcga gtcattcctg gtatgaagga taccgctgat 62880 gaagtagaag gaagagcatt agaaaatttc caaaattcta ctggagcatc tctcaataaa 62940 gaagaccagg aaaaagttgc aaattatcaa gataaacgaa tgaacggaga ccttggtccg 63000 atagcaaaag gattagataa aattgctaat tggaaaactc gtgcatctaa ttggattcgc 63060 ggtgttgata ataaagaagc actaactacc gacgaagaac gtgcagcaga agaagaaaaa 63120 ttaaagcaac tttcacctga agaaagaaaa aatgctttaa tgaaggctaa tgaagcacgt 63180 gccgcgatga ttcgttttga aaaatatgct gattcagctg atatgagtaa agactcaacg 63240 gttaaatcag ttgaatctgc ctatgaagac cttaaaaaac ggatggatga cccggattta 63300 aacaattcac cggcagttaa aaaagaactt gctgctagat tttctaaaat tgatgctact 63360 tatcaagagc tcaagaaaaa tcagcctaat gccaaacctg aaacttctgc taaatcgcca 63420 gaagcgaaac aggtccaggt tattgaaaag aacaaagcac agcaagctcc tgttcagcaa 63480 gcatctcctt caatcaataa tactaataat gttgttaaga aaaatactgt cgttcataat 63540 atgacacctg tcacaagcac aactgctcct ggtgtatttg atgcgactgg agttaattaa 63600 ggaataatat ggcaattgtt aaagaaataa ctactgattt aattaaaaag tccggtgaga 63660 aaatttcagc cggacagagc actaaatcag aagtagtaac taaaacatac actgcccagt 63720 ttccaactgg gcgtgctagt ggtaatgaca ctacagggga cttccaggta acagacctat 63780 ataagaatgg attattattt actgcataca atatgtcatc tagggattct ggaagtctta 63840 gatcgatgag atctaactac tcttcttcat cttcgagtat tttacgtaca gccagaaaca 63900 ctattagtag tacagtatca aaactatcaa atggattaat atcaaacaat aattcaggaa 63960 caataagtaa agctcctgtc gcaaacattc ttttaccgag atctaaatct gatgttgaca 64020 catcatcaca tagatttaat gatgttcaag aaagccttat cagtagaggc ggaggtactg 64080 ctactggtgt gctaagtaat attgcttcaa ccgcagtatt tggggcactg gaaagtataa 64140 cacaaggtat aatggctgat aataatgagc agatttatac gacagccaga agtatgtacg 64200 gtggcgctga aaatagaact aaagtgttta catgggattt gactccacgt tcaacagaag 64260 atttaatggc tattattaat atctatcaat attttaacta tttttcttat ggtgaaacag 64320 gtaaatctca atacgctgct gaaataaagg ggtatttaga tgattggtat cgttctacgt 64380 taattgaacc tttatctccg gaagacgcag ctaaaaataa aacactattt gagaaaatga 64440 cagcaagttt aacgaacgtt ctagtagttt caaacccgac agtttggatg gtgaaaaact 64500 ttggtgcaac atctaagttt gatggaaaaa cggaaatatt tggtccatgc caaatacaga 64560 gcattagatt tgataaaaca cctaatggta actttaacgg attagctatt gctccaaacc 64620 tccctagtac atttactctc gagattacta tgagagaaat tatcacgtta aaccgtgctt 64680 ctttatatgc ggggactttt taatgtattc tttagaggaa tttaataatc aagcaataaa 64740 cgcagatttc caacgtaata atatgtttag ctgcgttttt gcaacaactc catcaactaa 64800 aagctcttcg ttgataagtt caattagcaa cttttcttat aataacttgg gcctaaattc 64860 aaattggtta ggattaaccc aaggtgatat taatcaggga attaccacgc taattacagc 64920 tggcacacaa aaactgataa gaaaatcagg ggttagtaaa tatcttattg gtgccatgag 64980 tcaacgtact gtccagagtt tattaggctc atttacagtt ggtacatatt taattgactt 65040 ctttaacatg gcatataact catctggatt gatgatatac tctgtaaaaa tgccagagaa 65100 tagattatcc tatgaaactg actggaacta taattctcct aatattcgta taactgggag 65160 agaattagac cctttggtta tttcatttag aatggattca gaagcttgta actatcgtgc 65220 aatgcaagac tgggttaact ccgttcaaga cccagtaact ggattgcgtg ctttgccaca 65280 agatgtcgag gcagatattc aggttaatct tcattctcgt aatggattgc ctcatactgc 65340 ggtgatgttc actggatgca ttccaatatc agtgagcgct cctgagttat catatgatgg 65400 agataaccaa ataactacat ttgatgttac ttttgcgtat agagtgatgc aggctggagc 65460 ggttgatagg caagctgcgc ttgaatggct tgaatctgct gctataaatg gtattcaaag 65520 cgttctcgga aatagtggag gtgttactgg actatctaat tcgctttcac gacttagtag 65580 actaggagga acctcaggaa gcatttcaaa tattagtata ctatgacagg gattgtcaat 65640 tcgcagagta aaatattagg agcaatataa caacggggac ctttcggtcc ccatattttt 65700 atttgcggaa tgaaatgaaa gcagaaactg aagcaactaa actgtcttca atataaactt 65760 caatttttac cggagcttct gactcaaatt tacctgttac tacaccctga aaaatacttt 65820 cagtctgttc tggctttgaa aaattttcag aaggaaaaat tccgaacttt ttatctgttc 65880 caaaaatttt aataaattca tcgtaaaccg cttcgttaaa agcattatca gcaggaataa 65940 cgccttcaac tacaagttct tgacctaaaa agcgtaaaga agatttcatt ttgtgttcct 66000 catgttatgt cagtaagact actataacac aacacgaggg acttgtaaac tacattttga 66060 actttttagt acgcgtaata ggcatgcgtc gattttatac tgtttcattg tttgaagagc 66120 agtatcaaaa acagcattaa tgacaccaat tggatttcca cccaagtttt taagcttaac 66180 taatgatagt ttctcattaa cacctatcat tacgatatgc atcattttgt cgcctggttt 66240 aacgtttttg tttgtatcac cgccagaggt gtatgtacaa aatctaaatc caggaagcac 66300 gctttcttcg ccggcttgaa tagcaaaaat ttgtggtatt ttatgcttag gatttaagtt 66360 aacaaccggc gccgaagcgc cgtcaaataa ttatgtaata agttccatga tttatccttg 66420 aacgaacttg taaggcatgt ttgcaatatc tatgcaagac gcaataattc caagagatga 66480 ttctactttc tgtttaacat ttgatgaaac aaatgatgca aagtcaactc tgtcttctat 66540 ttcaatatca cctgtcattg caactacttc accagtttcc attagacggt caccgtcata 66600 aattactgat tcggtgagtt cttccgtagt cataacttca gcttgaatga gttttgtatt 66660 attaaatgtt gttccgtcat tattagaagc atcagttatt ttattaactt tgaccatcaa 66720 tccacgtggt agaataactt cagcttctgt tgctattccg agacttcctg gatatacaac 66780 attaacttta tgagctccat caattgccca tcctatttga actttaacgt attcaggatt 66840 ttctttatac gctcttattt cgtttggatt aatagttatt ccttcttcat ttttatcaac 66900 tgtcaattca ttacgagctt ctggttctaa aagaccgata ccagcatgtg taattccaaa 66960 acgtccaaaa atgataggag ttaaagaagt agatacaaaa tttctgaaat agaacacttt 67020 atttttaact aatgcttcgt atataggagc agtcatactt tgagcacgat aaactgtaat 67080 gccttctggt atacggtcac cattttcaaa agctgaatct aaattattta tcgcagattc 67140 aatttctttt tcactcatta catcatatcg ttctggattg tagcggccta aaagaagatt 67200 attgatgtca gtatatcctg atccacaata ctctctaatg ccgcgctttt gcgatggagt 67260 atatttagaa ccatcacggg caatagtaat atcaatcatt ggacctgcac caattccaga 67320 aaaactataa atcattcttt tgaggaattt agtttttgct gcgttccaag aatttttagt 67380 tatttcttcc cagacatcat ctggctgtcc tttacgggtt ttattatgtt tatcaagcca 67440 attatcttta tattcttcaa agaattgatt aacagctgct gcgtatttct ctaaacattt 67500 tattgaagta gttggttcat ttttaatcgc attaagaatt acatctttaa ttttttcaga 67560 aacttcacca acctcactca ttggaaagaa tttatagtca taatgaagtt catctgcagt 67620 tccttcagca ataatttttg ctgccttagt tttagaagct attgaattaa ttccaagttt 67680 catttcttct gcttcgggaa ttaaaggagc tgtagcaggt ttattgaaat tagctgcagt 67740 agattcatac ttttggaata attcactttc aaatctagaa gattccaatg actgactttg 67800 tgcaattgct ctacgggaaa ttttaacttt aacgattaca gcttggtcag aacgtttatc 67860 gttttcttgc gcaatagatg ctgcaattgc ctcgttttta gttacttgag ctccagtatc 67920 tttattgata taaacatcac cgaccttcga ttcaacttta gtaaagagct cggtactaat 67980 ttccggaact cctggaatgt cttctagtga tacatttttg cgatgtataa gaatatatgc 68040 atacttttta tcataatccc agagttcctt aagaaggacg tatctgccac ctgaacgact 68100 acggataagt ctatcagcaa taacttgaat ttgtcgagct tgaccagcgg ttttagactt 68160 aagaatacgg agcatacagg catcaatttt atactgacgc atcgtccgca ttgcaacagt 68220 aaaaaccgaa ttgatataat taattgggct tggaccaaga cctttcaatt tagcaattga 68280 acctttagcg gttaatgtaa aaggaacaat atgcatcatt ttatcgccca tctttaaatc 68340 acgattagta tcacctccag atgtataggt acataaacga aagcctggtt gttcaattgc 68400 gtcatcaaca tgaactgaaa aaatttgtgg tattttcttc tttggattta agtttgtaat 68460 tggaagagta gtatcttcgt caaataattc tgtaattagt tccatcatat cctctctagt 68520 gtttattcta tttataaatt aaaggcccga aggcctttaa taatctaatg gtaagagagt 68580 acgatatatt tcaaactttg gccctttttc ataggcatca aatgtttctg taaatttatt 68640 ataagcgtat gcatctacaa attcgagaat gacttgtgat acagaagtag aaacatctcc 68700 accttctttt tgagctacaa caattgtttc taagtaagct ttcatagacc agttacctca 68760 tgaaaatcac caaatacatc ctcaaatgta ttagctttag ttttatcttc acgtaaacga 68820 atcgcaatcg gaagaaataa tttaacgtaa tcagtgcggc catcagattt taaccaaccg 68880 ttgcattcgc actctagaat ttttccaata taataatttt ggttttccat aatgcgagta 68940 cggtcaagtt catgcgattt tacaccagct ttatctttta aacctgaacc agcattgact 69000 ttaatttttc cacactctga ttcaagaata aatccacccg ctttagtagg gtctttacgg 69060 tgaggataaa ttcctacaat ttttaaatca acatcaatta cttctttaaa tttatagaga 69120 ttttttgaac gagtattttc ccataatcca tcgatatttt tgagaataat accttcaaga 69180 ccctggtcaa tatacttttt ataaattacc ttagcttcat ctaggttatt tactagctgg 69240 ttttcaatta aaattacttt atcatatcct gatgtcattt gttctagttt agaaaaacgt 69300 acatcatatt ttaaacgaaa cgccggaaga ccgtatattt ctaccaatgg gacataatcc 69360 cagacctgaa acttcatgca ttgagcttct ttttcagaaa tggttccctt taaagattta 69420 ttagcgattc cattagaagt agtacgtgat tcagctactt cggcgaattc tttggcttta 69480 ctaatttcag gataagcatc aaaaagaaaa tctaggcctt ctggctcctt tttaacttgc 69540 tcatggtata ccaattcgcc atcaattaac acgccttctg gatgaatctg gcgggcttca 69600 gcggtcattt tgattaattc ttccttaaga agatctaatc ctagatattc attaccggct 69660 cgtgataaaa gacgaacatc atctaattca tcacctctga cttcggcaaa gcaccgagcc 69720 ccatcagctt ttaactgggc aaaggctgga aatttgatat tcttattaat gcctttttca 69780 tcgaagaac ttgcaagcat ttgaggttgt tcaggaatta aacctggcca aactttgttt 69840 gcaatagata ctgaagcacc gcattcaagg tctcgcatca tcacccgacg caaaacttca 69900 acatcatctt ttttaccatc ggtgatatat ccagttaatt cctcaattgc tgcatttcca 69960 gtcaatttcc gagtagctaa tgtgaattca atgaagtcaa gcatatcggt aagagtcaac 70020 attccaaaac tctgggtagt aataccaggt ttaggccatt tcttgatata atattgtaac 70080 ccacgagaat aagtcagacg atatactcgt ttaagcaatt cattatcttt attcttttca 70140 agaattgctt gcttctgctt agttgaacca atagatgcta tttcgttcag aattttaaga 70200 atcattgttc atccttcaga gtttggttta cagctctatt ataaatcaat tcatcattaa 70260 gctcagtcaa agacttatga tatgtggttc taactttatt tccttgcatc cagtgcttga 70320 tataaatgaa accttgctct acgcattttt taaaaattcg ttcgtctttt tgagctcgga 70380 attctggatt gcatctaaaa aattgattta cgtgaccgta atcacgtgta gtattacctt 70440 cattttcata aatagtgtga acaacaaaca ttagaatgct ccttggaaaa tattatcacc 70500 acaagtaggt ctattataca aatactctat accgccgggt ttaatatagt tccatgtctg 70560 aaacggatgt gtctgatatg gatgatatag atgattataa ggattaaatc caggagttct 70620 ccaggtagtg ttccaacgaa aagaatcgtt tttaatcatc ttttcaatta catcttttat 70680 agctttttca ctatcaaaac tttctttatt ttcctttggt gaaaaaagct tattctctac 70740 atcgttccat gtataaactc gctgagcagt ttttggaata ctgtcacgtt cccctcgagc 70800 catccaataa actggaacat ttaatatttc actcgcatga tcgcagtgat gagcgagatc 70860 gtcaatataa caaattacgt tatatttctc ttttgccttt ttgaacagct cttcttttga 70920 agaatcatga ccacacatca ttacttctga gaaggcacca ggaaaaagag cattcaaatt 70980 aaattgacga ttcaacagag cgtcaataga atcacccagt gctgtaacag ctacaaaatt 71040 ataatcttct tttaatttgt taattacaca cagagcatct ttatatggag acaagtaacg 71100 aataaaatct gaacgattgt atttttcaat taacttgaca ccaagttctt catcacaatt 71160 aaagagttta cctggagaaa taaatttctc atcttggatc atttttaaaa tatgttctaa 71220 tggaagatta tatttctgag caaaataagg aagacctgat tgccagctta aacatactcc 71280 atcaatatca gttaaaatag taggcttcat agagagtctc ttaataggtt taacacatca 71340 ataaattcag cttcggttag tattgtatca tcttttgtta gaccactagc catgctgtgc 71400 ttcaaaactt ttcctttcga ggcttgtaat gcatcacgaa agcccttgtt ttgaatcgct 71460 gcttcaaaat atgcatttgt gtataattct ttccacgccg gggagtatct tgaaaacgga 71520 actccaagcc agaagagggt cccacggtcc tgagctctag cataagacct tccagcttgt 71580 tgagcggcaa gcccggataa cccaaatata cgacgttgtt gttcaacatt tttcaccttg 71640 cacccttgga ggaatccttc aagacctcca aattgaatac catccataac gaaaggccat 71700 tgggcgaaat tacttaatgc acatgatggc cacctaaaat tgcttctaat ctctaactca 71760 gacattttca atgcttataa tttcaacatc agcccaatga ccatagcaag gaagacgaaa 71820 ttcaactggc cagttagggt ccttttctaa tataatagac ttaacttgcg gttcttcatg 71880 ttcatcagta tatggatttt tatccgttac tttatatgtg accttaatgt actgaattcc 71940 aaaaatctta ttaattatat tcatactaat tcctttaatc cgtaaatagg agataattca 72000 tcacccatac gaaggtcttc atttccatct acccaggaaa caatataagc ctcttttatt 72060 tgaataccac tccatttaaa tggaggtaga accttagaaa ttaatccagg tataccaact 72120 ccctttaatt caacagtttg acctaaaaag aatttcatta gaacctcatc tgaaagccat 72180 gtgatttaac attaccgccg ccaatatcag aaatgttaat ttcacgcgca attgaagggt 72240 caatgtcaat ttcacgattg agtttagcga tagctaaagt atcgcgccca tttacagtac 72300 ggaactctaa aggacagact acattaacat agtttttaat cgattcactg gtaggttgca 72360 aatgagcagg aaggtcttta ggcgcctttg agaaaaccac ttcacagaaa tttttgcggg 72420 tgtcaaaata agtagtcata aacatagtat tttcctcaat agggggccga agcccctgtt 72480 ttattttaaa tatcaaattc gttaagaact acatcaaaga ttgcttcaag atgctcaggt 72540 ttagctctgt tactcaaaat atgacgaatc caagttttaa ccagaagctt acgattgacg 72600 ccattccagc aaggatgagt acctaaatca cgttgacgga aatcatcatc taatgcgatt 72660 ttaaaagaag aaccttcttt cgtgattgaa accgtgatgc cattttcaaa tcgcatataa 72720 acgtaattag gagtcatata ctgttcaatt tcgcatactg atccattttg atgtttccaa 72780 aggcagatag tatcaataga acctgcaata ccgttagaaa catatttacg ttcaaagttg 72840 atgtagttca tttttattct ccgagatgtt taattgcggt acaggtatat aatatcatat 72900 cctgtaccaa agtaaacaat tattttacta ctttccagtg ctgcatgtca agtttaccaa 72960 cttttttcat cttctcaatt aagcgttcgg cacgttggcg cgctgtaaca taataccatt 73020 cacctaattc attttgttca atttttccaa caattactgt attcaattca taaatccaac 73080 cagtaaagaa attatgaact tgaattgtaa aggtgaaatc tgttcccata ccttctgttg 73140 tttctacttc aataatatca ccttcaactg ccattaagaa ccacatagtt tcatcatatt 73200 taccattgaa gcatttagtt ttaactgtag cgttcaaatt aatcgttttc attttattct 73260 cctttgtttg tgtaagataa tactatcaca aaggaaccgt actgtaaaca actttgtgca 73320 atctttggaa aataaaaaag gactcccgaa ggagtcctca acttatgctt tctgcttacc 73380 aaaacgagaa gcatcatctc gaagaaccgc acgtgctcgg cgcatgatct tctcaacagt 73440 ttgattgata cgagagttcg acccacgctt gtaaccagcg cgtttagaat caccaacttt 73500 cttttcaact gctttctttg ctttagcttg ttttgccatt ataaattctc ttttaaatga 73560 aaatgcagga cttattggca ttgcctgcgc aagccctcaa ggggaacata ggtttttgga 73620 tatttaacga ccaggataac cataaacccg tcatcattca cattcaagag gtacaccgta 73680 aaactgccgg ggtcttaaaa ctataatgat tcgcaaatca ttaatcagac agttcgacgg 73740 ctcctcgatt ttagctcaca ctaaggcagt gaatctccag taaattactt cagtgttacc 73800 acaaagtgac gaactgcttt tcgtgcagca gaagccagag gcttagcata tttaagttca 73860 tctttttcct gaagctcagc agctaatgca gtttgagcag gattcagatg tttgaaataa 73920 cgcaggattt caagagcttc ggcttcaaca tcaatagatg cgccatagtt ttcgtgacca 73980 ttattccatg cgtttcgttg cagttcaaga gcgtgttgta gttgtttaat catttaaaaa 74040 ttctcgttag agattaaaac tcggtagtca cgttcttctg aatttcatct tctttcgaca 74100 gatctctcag ttgtagacta ccacgtagaa ttgttcggtt aacttattat tccgacaccc 74160 aattcatatt attatttata tcacttataa agacacggaa tagctttata gtgacaagtg 74220 acgaattttt gtttaatttc ttttggctgc ttaagaccca gagctacaaa aggatgcgga 74280 acgtttcgaa tttgaccaac tggcagagaa gtcaaatcac caacttcgca gaaaccttca 74340 ggaacatcag gaccaacaga gtgaattaca cacagttcag gaacttcacc ttgaacacgt 74400 ttaccgataa taagtcctga ttctgtaact tcttcatcac cggcttgtgc aggttcagaa 74460 actaaaataa catattcacc tacagcacga attggtagct gttgtacttc agacatcgtt 74520 tttccttttt gttaacagat gagttaataa taacaaataa ttcttaaagc atttatttac 74580 caataaattg aagcaaatgc tcaactttca taccattaac ggaaatcaat ttatcaatag 74640 aaaaacctcg ccatgcaccg agttcaacat caaataccgg aatcatatca gtagattctt 74700 tccgagcaca ttcagtcaat ttaccagttt gcatggttgg cataaagtcc gcatcacgag 74760 tgcctttcat agtacgaata gtaccatcag acttttcaaa aactacgttt gaaaccccca 74820 tggacaattt agttttcaaa atttcacgaa ttgctacttt ttgttcagtt gtcagtttca 74880 tttatttacc tattacagtt ttaatatgag ttgttccacg ttctttaaga gtggaaagca 74940 atttttggca tttttctaaa tcagatttcc aactatacgg cctatcaatg caaacccatt 75000 ctgacttata atactgtttc catttagaga aaaaatattt cttatactct acagcaaatg 75060 aaatgttctc gttagaataa gaactaattg ctgtgagctg taccaaacga aatttcatta 75120 ttcaccacag aattcgttga tattttcccc gtttaactta ttcaagtttt tcttaggaac 75180 attaaacact tcaatacccg catttcgcag aatatcatcc cagccaggtt tatttttatc 75240 gtatgtttcg caataaacca gctttttaat tccagattga gctattgctt ttgcacaatc 75300 tgggcaagga gaaagtgtta catacatagt agcaccttca attgaagaac cgtttcgtgc 75360 agcaaacaaa atcgcattta gttcagcatg aatttcattt ttagacgacc attcagagtg 75420 agcactacga tgttctttcg ccaagacaaa acgatcagtt gaaccaaatg atacgcattc 75480 aggcttatga ccttgaatga tagtatgttt aggcttattc aacaaccaac cttgctcagc 75540 agcataatca cagcagttca ctccccctgc gggtgaacca ttatacccag tagaaataat 75600 acgtccattc ttttcaatta ctgctcctac cttccaggag caacattttg attcctgcga 75660 tactaaatat gcaatttgaa gtactgtact cgctttcatt tcataatcac cagataagca 75720 gatttagcag tttcaacacg ataaatttcg tgacgaagtt tagttatact tttaataaca 75780 gaactaatta tattctgccc gtctttaaag cggtttttct tatcaataaa aactgcgcca 75840 gtcatctttt tgtgaagctc aactggatac ttcgtcacaa taatagcatc atacacagaa 75900 ggatgaatac tattcaccag agtatcattc attaaagtta ttctaatgaa ctttgctgtt 75960 tcagaatcaa gcgctctatg atcaccagta tcattttcaa gacaattatc aattatatca 76020 gttaaattca tcatagtacg ccatacaccc tttgtgcttc aactaatcca tcaaaatcca 76080 gtttaagatg cgatatttga tcgccatcac ctggattcac aattactaat actgaacgag 76140 gagtttcggt aataacacga accgatgttt caggaaatcg ttcagaaacc ttatttacta 76200 attcctgtgc aaatagttta actttttctt ggaattcttt aacagtaatt ggtttttcac 76260 ttagcatgtt gatcccagct ccttactttc aacgttttta actaatttga cagaaactaa 76320 ttcagcatct tgagtaatca ttaccggacc ttcttcatac tcttcaagat attctagagc 76380 tttcttttta gcttcttcct tcgtatcagt ttgagcatag atataaaaca tacaaccagt 76440 aatacctact actttccact taatttcttt atcagcttta atttcaaatt tactgacaga 76500 atcatctttt tgaacttctt cgaaaaaaga atattctaac atataagcaa ttgaaaataa 76560 cgggctatct ttataggatt cgcccattac atcaatagct ttataccagc agtcatcaat 76620 tttgcgttta atgctaataa cattctttgc agggtcaatt tttactttaa atgaattttc 76680 cccaataaac tgggaaattc gtttattagc cccgcaagtt tcattaaaaa tatctttata 76740 tccagtttta aagcgataaa ccttatcttc ttcaaaccat tcgctcattt caatttcctc 76800 atttgttttg gtagagctat aatatcacaa ctctaccgta aagtaaacta ttaaatcgct 76860 ttgaattccg cagtttgaga ttcaaagcga atatcgcctt tgatgactag ctcagcatca 76920 agaccgaata caacaatgat atgcgcggaa cctggataca acgtgatggc aacagaatcc 76980 acctggtctg gaagcaaagt attcaataca tgagtcactt gagcgtggat tcgaagctca 77040 gctgcgttat caagtttttc aaacatatta ttagcgataa tttgactaaa cactacttct 77100 acgattttag agtaagtcgg aaacatattt acctcacata attttcttcg agccaattaa 77160 taatagtcca agtttcatgg tgccaagcca ttaaaaatct cccgaggcga cttgccagca 77220 ttcaacaccg atacgacgcc acatttctac tacttgagtt cggtcatcaa tagctaattt 77280 cacatcaaaa tgtggtgcga tgtgtttcca gaaaatttct tctttaacta catcatcttt 77340 acgggtatca ccttgttcgc gttgacattg cataactaat ggaacgccag caatatcctc 77400 aacccattta cgggtcatac gataatattt cgttgggtct tctttagttc cactttcacg 77460 acctgaaacg actacgattt gatacccttg cttatcgtac atcttggaca gttcaacaac 77520 catgggatta ataatatcgg tatcacattt ttcaaggtca taaggaccac gaccattcat 77580 ttttgctagt gtgccatcaa catcaaaaat aactgctttt ggtttaccag gagtcccttt 77640 atataccgga agaccgagat actctcgcat gcttttgtac attgagcgta aaatatcaat 77700 tggtactgct ttagttccac gttttgagtt acgtttaacc aattcagtcc aaggaacatc 77760 aaacacttta tattcaactt tccagccgta ttctttggca aaagtttccc atgccaggcg 77820 acgttcagga ttcaggttag tatctgaaat gattactccc ttaacagaat cgccaccgta 77880 cagaatattt ttagctgtat caaactgcat accagttacg ataccttctt tctttttggt 77940 atacttatac tcgtcacgtt cttcatgacc catgatggat tgacgataat catcacgatt 78000 gatattataa aacccgggat tcttagcaat aaattcacga gcccaagtac tcttacctga 78060 accaggacag ccaatagtca aaataatctt tttcatcatt taattcctaa gaaaacttca 78120 agaatacgaa tattatgctc acgccgccct ttatataatt cagctgttga ttgattcacc 78180 gatttactct gaacattgga tgaaataaat tttatcatgt gatttttaag ctgatacata 78240 tcaagcccac gagctttcgc ttcttttcgc agggctttac cagcgtcatc taaagcttta 78300 gcatgttcaa tgtcttcgct aatgcttgat gcactttcat gacatacatc aatgtaacgg 78360 tctgagcatt caatataacg ttctagaaga gttttcattt attttttctc aaccaatgat 78420 tgaatataat catgcaggtc tttagatgct ttaccccact tattttgata ttcatttttg 78480 agattagcac gtgattgagc taataaaaca tcattagttg gaggtaaaga ttctaaccgc 78540 tgaatctggc gtccataaat cattgcagcc atctcggatt cataaatcaa tcctttgaga 78600 tgttcaaatt gatgccgtga aatcatttac atttatcctc ttttaactct tgacgataat 78660 aacatatcat agttttctgg tcatgtacat atcgttttac atcattaagc caaatacgaa 78720 attcctggga atcttcaaat ggcataccga cccaagcttt accatcgata actttaactt 78780 gccaagatag tttagcttca tcatatgact ttatttgtac aggccaatta ggatgaactg 78840 tttctttctt tacttctaga ggctttgtcg aacaaccaac tagaagacca atagataata 78900 ttactgctga tagtttaatc atttagaaag gtcctggatg tcttctgcga acttgttgaa 78960 ggagttgttg atttgttttt caaccaatcc tggcttatga gccaccacat ccgccttctt 79020 tgcgtctttg cgcagttttt cattttcacg ctcaatagca gcaattgcct cacgattttt 79080 attattcatc gcatcaatat aattatactg aattcgcaaa ttatttaatg ctaaggcgtt 79140 ttcattggac gtttttgtaa tttctacaac agacgtttct aatctttcta ccttattttt 79200 taaaataata gatgttccgc caaatgctat tacaagtaat agcaatccag ctgtaaaatt 79260 acttacatgc ataaagtttt aataacctct acaatatcgt cttgagaaag accgttaatt 79320 aaaatatgat gttcagccgg agatttagaa attttaaagc atgcctcaac atcttctgcc 79380 atatccgatg cactacgatt tggattacta accccaaggc ggtgttttcc agtcaaagga 79440 ttaacgatga tatagcattt gcaattattg atatgaacat taggttgagt ctgattaatg 79500 aacacttcac aatcatattt cgcaagctga ttttctaaaa agactttcat ctcttcaacc 79560 gcatcaggaa gcatatcacg ggcttgctca agacgacgat ttcgatattc tttaatggtc 79620 gttttccgct tgacttgctt tgctaaatct ttcttaagat cggtgatata tccaactcga 79680 cgatttcctt tgaatacaga aatcccatct gtagtatcac cgtatgcttc aacgaccatt 79740 tcagtagtaa taagttgtaa atccatcata aagtcctcat gttatgtcag taagtctact 79800 ataacacaac acgagggact tgtaaacagc ttagtatcct tctgggataa attttttata 79860 atttttcaaa aaattctgtt cgatttcaca catgaccttc tcttgactat catacccttg 79920 gtagaggctc atgatgatac cgaacaggtg atccattcca gcacctttag caacaccttg 79980 tgcttccatt gcataggtct ttctatcctt accacaatgc ttattgtgac agtcaagaac 80040 taaaaacaga gctcggtcta agtacttcag ataagtcgtt tcaaatgctt caatttttct 80100 gtgtgaatat tcatcgtcag cgtacattgc tttaagatca tctgatgcac cgtcaataat 80160 agtcttaaac aatttttctg gattatctaa tgaacttttt gtgctatgaa gagacacata 80220 ccagtcagac ttaattttaa aatgagaacc atctttcatc acagcaacat agccttcgat 80280 gttttctgca tttttagctt cttctaccca tttaggacta tcgatttcgt atcgttcaac 80340 tagatacgga cgaagaatag catctttata aatatcatca tatgaaatgt attcacccgt 80400 ttcgttttca cgaacattca ataaaatgat tttcatctct tgataagcaa gaacgattct 80460 attcgtcgga gcgacgaatt cgaagttagc agtaaatcca tcttcggcta attctttaag 80520 tctgtcgcgc aactggtgat gattaatatt catcaaaatt ccattagcca ttaaagcctg 80580 ttcggatttg attgaaccct ttgatttgaa cagaatttca tcaccgtcta aataagttga 80640 taccaaagac ccatcttctt ttgttagaat gtaatcaaca tcatttaaat cgatattcat 80700 cgtgaatgga ttttcattca agttaaaaaa cttttccatg ggacgagagg caattcttac 80760 cggtttttct ccatccattt caaacataat tccacgacat tctaatgcgt ctggaagtaa 80820 ccaatcagaa taagatgcat aattatatga gaaaattctg taagttcttc cagatgcact 80880 tacatcatcc gagtaaaaaa acttacgctg tgaatcctta catagttcca ttaaattgtt 80940 aaaaagttct tgcattgtgt atcctctttt gtgttttgaa tatagtacca cactccatgt 81000 ggaagcatca ttttttcttg tgttgaatat tccaaggcgg gttaaacagt ttaatgaata 81060 gaggctcctc taggtcaatc gttgcgattg tcattgtacc taactcattt gtcatagaaa 81120 gattaaaaca ttggcgggcg taaaattcaa ctttgcttcc ttcctttagc gcagtatgaa 81180 ttaatgcaga tttagtagaa tcagacgttt tgtctttacg gttaatagca gttctataat 81240 agtttattct tttacgtaaa tttttagttt ttccaatata aacaagctca tcatttatag 81300 caatagcata aattacgtta tacttgtttg gaatagataa ttgttttata cttccgttgt 81360 cgtctaattc tagctcagta tatttaataa atgaatattc tgttgcaatt tctttcataa 81420 taaaatgggc cttgcggccc actccttaaa agtatttttt aaaactcatc ataactttat 81480 catcaacatc attatcaatc tgtgcaacaa ggtaagatga cagttctact tcttgtggcg 81540 cggattgaac attatcagaa ttaagatatt cacgaatcca aggatatgga tgtttaaccg 81600 gagcatcggt aattgggcat ggaagaccac actgtttcat acgagataca gttaagtaat 81660 caataaagct ccacatgcta tttgtattta atccaggaac atctccatct ttaaataaat 81720 gaactgccca atctttttct tggcggttaa cttccatgaa aatatcaact gcttcttgtt 81780 cacactcttg agcaatttta acccattcat caccatcagt accggattga agctgacgaa 81840 taatatattg ggtgccttta aggtgaagct gctcatcacg cgcaatgaac ttcataatct 81900 tggcattacc ttccatgatt tccatgttct tatggaagtt aaaggtaccg tatgttcgat 81960 tgagctcgct aattctcaac ccgttctctt atgaactgct gcatgttacc atgcagtcca 82020 gactatatca caatcccgga gggattctcc ccatttcgag tcgcttgacc ctacgtccga 82080 agactagtcg ttgaaccttg ctttgcaatt gtcgccgtgc catcgtttat atgttgatgg 82140 tgataaatct ttcttatcac aatatggaca attcaattga attctatttg gatttaattt 82200 aaatctatcc aaatttttct atagttcaat tgtgcatcct cttaaaggta taatcatatt 82260 ataccaatta aaggtgcaaa caaaaccttg gctgctagtt ttccatttct ggattttcca 82320 gcaatttaaag gagttttcga taagcattac tgcttaaagg cgcattttac gcgaaagata 82380 cataaaaacg aatagcttcc aaggcgttga taacatgcaa acagaggtaa agagatttca 82440 ttagtgctcg tttagcttcg gcttcttgtt taatagctcg atttaaacga aaaacagcat 82500 caggagattc tttagctagt tctacaaatt ctttagcatt ttcccattca cgggttttaa 82560 ccaagacatc atcataatag cgaccgatag attcagcacg tttcatgata gcttcatcta 82620 atacaatctc atcaaatacc tttgacggat cagtataaag atttcgcatg atatgagtat 82680 atgaacgact gtgaatagtt tcactaaaag tccatgtagc aacccatgta tcaaggcttg 82740 ggtctgaaag caatggcata agtacagcag acggtgcacg accttgaata ctatcaagta 82800 atgattgata cttcagatta ttagtaaaaa tattttgttg atactgagga agcttattaa 82860 actgtgcagc atccatcatc aagtttactt cttcaggacg ccagaaaaac gagagctgac 82920 gttcaataag ttcttcaaat actcgatgcc gttgaatatc ataacgcgca ataccaagac 82980 ccgaaccaaa aaacataggt tcttttaaaa catcgacctg tttagtatta aaaactgtac 83040 tcattatttt gtcctgtaaa ctaaatttcc acagtcccag attcttctaa gaccatttgc 83100 ataacaattt tctacttcag ttattgtatc atcataattt ttaagcttgt ttttaagctt 83160 atgtttcata tagcttgagc ggtgaaatac ctctccttta tcgacatacc aataacatgg 83220 ctcagagata tgactaaatt ccatgacaga gtcataaaca tttgataatg tactgcacca 83280 tcttcgattg ccataagata gacaattaat tccttttaat aattttgagg ctcctcctac 83340 aacacaaatc cctaattttg aacacatcct taaaagttca tcacctgagc tatatctaga 83400 tttaccgata gaaataattt gaactaactc attattgtaa taaagtcctt tatacgtatg 83460 agctcctgag caaaatcctt gaagatgatt cttattaata aattcttttg cctcatcctt 83520 attaacaaaa cgtgctttgc attttcgggc tggtattctt tctgataatc ctaatttatg 83580 ctttataatg gatttccaga tctctctttt tgtatcatca atccattcat tttcgaagat 83640 gtgaagtaat tgaattcctt gtgcttcaca catctctgtc ttcatcaaat gataagtttc 83700 tttaatttta tctgtttcct ttgacccgct agaatgccaa taaattccat cgtattctat 83760 agccaatttt ttctcaggaa tgtaaatatc taattcatac ggaggaataa tttttctagt 83820 ttctacgcaa tcaaatccta gatctaaaat gaattgctct atagaacttt gagtataatg 83880 aacgtcaatt agtcctttgg atgaaagagc tctataagcc gtcatccgag aacaatttgc 83940 taattgttgt agttcttcta tagaaatttt gtaattgatt ttatctagta tatcatgatt 84000 aatatgaccg ttatttttaa tagattttcc tatagatgaa tataacgatg ccttatattc 84060 ttcagtccaa tttaatttag tcttcttaga tttttcgcga gattttctag aattcagaat 84120 atcaactaat ttaccgtttt ctataacttt tctcgcttct ttcacacttt ctaattgtga 84180 attatgcgtt acaccatatc gttcaattaa agtttttcta tttttatttc ttgaaatttt 84240 ttgatgagtt gttccatatt tttctaaaga atttttgcgt tgaagttcag acaaatattt 84300 tttatatttt tcttttccgc caaaatttgt atcacggctt tgaattctct tatccgcgaa 84360 aaatatccct gcgcaggatt tactacatgt tgctggaaat acacgtttct ttgctgtttt 84420 cagagaaatg aaatttccac aaactgcaca ttttagatcg ttaatgtcaa tgccttccat 84480 aatttggaac acattgagct taaaatctat tccatcagtt agaagagctt tatcttcttc 84540 tgttagtcta gatttaagtt tttcttctcc aaatggaaga aactttccgt ttttgtatat 84600 attatcaaac atagcgttat tcttagttaa ccacatcctt gtggtaatta tatcataatt 84660 tacakgatga acaatcatct gcttttggag tttctatttc ataatcatca gtaccggaac 84720 catcacgagt attatgataa tagaaatttt taatgccata ataccatccg tatagcatgt 84780 catcaatcat tattgacatt ggaacctttc cttttggaaa aatctgcggg tcataatatg 84840 tattcgctga agctgattga catacccatt tcagcataat agctacctgc gtaagataag 84900 gtttattacc tttcttagct aatttccatg tataatcata gaggtctatg ttatgctcaa 84960 tattgggcac gacttgatta aaggaaccct cttttgattc tttaacagag actggtccac 85020 gtggaggctc gataccgttt gtactgttag aaacttggga agatgactca catggcataa 85080 gtgctgataa tgtgctatta cggatgccaa agagcttaag gtcttcccgc agcgccgacc 85140 agtcacaaac gtattttgga gctgcgattt ggtcaatctt tttattgtac cagtcgatag 85200 gtaattcgcc tcgagaccaa cgagtgtctg aataatattc gcaaggtcct ttttctttgg 85260 cgagcttaat ggatgcttta atgagtccat actgtaatct ctcaaatagt tcatgtgtta 85320 aatcgttagc atcttcataa gaagcaaagt tacttgccag ccaagctgca tagttggtaa 85380 cacctacacc gaggtttcga cgctttttag ctttttctgc ttcaggaact ggatatcctt 85440 ggtaatccaa aagattatca agagcgcgaa cttgaacttc tgctaattca ttaattttat 85500 cttggtcttg ccaatcgaag ttatccaaca caaatgcgct aagggtacac aatccaattt 85560 cagcatcagg actattcaca tcatttgttg gaatagcaat ttcacagcac aagttactct 85620 gacgaatagg tgccttttca cgaataaacg gagtatagtt attcgtatta tcaatgaact 85680 gcacataaat ccttgctgtt cctgaacgtt cagtcatgag caattcaaat agttcacggg 85740 ctttaatacg ctttttgcga atattagggt ctttttctgc ggcttcatac aattcacgga 85800 aacggtcttg gtctttaaaa taagaataat aaagctcgcc acccatttcg tgtggactga 85860 acagagtaat gtagtcgttc tttccaaaac gttccatcat caaatcattc agttgaacgc 85920 cataatccat atgacggata cggttttctt ctacgccttt gttatttttc aaaacgagaa 85980 gattttcaac ttccaaatgc caaataggat aataagcagt agcagcgccg ccacgaattc 86040 caccctgtga gcatgattta acagcagtct gaaaatgttt ccaaaaagga ataacaccag 86100 tatggcgtac ttcacccatg ccaatcttag aaccttcagc acgaatcata ccaacgttaa 86160 taccgattcc ggctcgttta gaaatatact caacaattga agcagaagct ttattgatag 86220 acttcaatga atcacctgcc tcaataacaa cgcatgaact gaactgtcga gtcggagtac 86280 gacaaccagc cataatagga gttggcaatg aaatctgtcg agtagatact gcttcataaa 86340 aacgaataac atgttttaat ctatcaacag gttcatcttg atgcagtgcc attccaatag 86400 tcataaatgc aaactgcgga gtttcataaa tttgaccagt ggttttatct ttaactagat 86460 atttttcttt taattgcatc gccccggaat aagtaaattc catatcccgc tcgtgcttaa 86520 tttttgattc taaaaatgta atttcttctg ctgaatattt tgacaacaat tcagggtcat 86580 atttaccttc atttacacaa taagaaatat ggtcaataaa tgaacgtggt tcatactgcc 86640 cataaacatg cttacgaaga gcgaacatta aacagcgagc ggctacatat tggtaatcag 86700 gctcttcaac cgaaatagaa ttcgcagcag ccttaatgac aatagtctga atatcatcag 86760 ttgtcattcc atcacggaga taagatttaa tattttcata taattcataa ggatctactg 86820 atgttccttc agctgcccaa gataaaactt taataatttt ttgcgggtca aagctctgag 86880 aaacaccact acttttgata acattaatta attgcataag tcctcaactt gaaaatcgtc 86940 tttaaacaat cggttaacta tatgagctat tatatcacca tgacacggct ttggtttaca 87000 tgtgcatcct agcctcattc cacgtaaagg ctctaaatgt gctttagtta tttctccgga 87060 tttaattcga cgtataaaat cttttttgaa taattcaatg gcagcctccc ggctgccagc 87120 atctttaccg acgtaaaggc tctaaatgta ccacggtgaa tattaacatc aaagtcggat 87180 ttgtatttat tcactacccg gcatagacgg cccgcgcggt tgtaggtgtt catattgttc 87240 ttccgttaaa acagtaatat catagtaaca gtcagaagaa gttttaactg tggaaatttt 87300 attatcaaaa tactcacgag tcattttatg agtataatat tttttgccat aaatgataat 87360 aggctgattt ggtcctggaa cttctaactc acttggatta ggaagtgtaa aaagaactac 87420 accagaagta tctttaaatc gtaaaatcat atatcctcgc aattaaatta aaattatacc 87480 gccatctttc ctttaattgg cgggtgagat acatagttgt taagaacaaa attatgcggc 87540 tttgcgaatt gactcaacca aaatacctgc gattctgtgt cccattcatc aaattcatct 87600 ggaaatttta attgcaattc gcataaatcc ataggttcac gacgtaaaat ttctttacat 87660 tgttctacgt gattcatata gatatgagta ttaccgccag aaaatatcaa atctcctgga 87720 ataagattac acatcttagc tacaatatga actaacgcag cgtatgatgc aatattaaat 87780 ggaagcatta tgttcagata aggtcgttaa tcttaccccg gaattatatc cagctgcatg 87840 tcaccatgca gatcagacta tatctccaac ttgttaaagc aagttgtcta tcgtttcgag 87900 tcacttgacc ctactcccca aagggatagt cgttaggcat ttatgtagaa ccaattccat 87960 ttatcagatt ttacacgata agtaactaat ccagacgaaa ttttaaaatg tctagctgca 88020 tctgctgcac aatcaaaaat aaccccatca catgaaatct ttttaatatt actaggcttt 88080 ttacctttca tcttttctga tattttagat ttagttatgt ctgaatgctt atgattaaag 88140 aatgaattat tttcacctga acgatttctg catttactac aagtataagc agaagtttgt 88200 atgcgaacac cgcacttaca aaacttatgg gtttctggat tccaacgccc gtttttactt 88260 ccgggtttac tgtaaagagc tttccgacca tcaggtccaa gtttaagcat cttagcttta 88320 acagtttcag aacgtttctt aataatttct tcttttaatg gatgcgtaga acatgtatca 88380 ccaaacgttg cgtcagcaat attgtatcca ttaattttag aattaagctc tttaatccaa 88440 aaattttctc gttcaataat caaatctttc tcatatggaa tttcttccaa aatagaacat 88500 tcaaacacat taccatgttt gttaaaagac ctctgaagtt ttatagaaga atggcatcct 88560 ttttctaaat ctttaaaatg cctcttccat ctcttttcaa aatctttagc acttcctaca 88620 tatactttat tgtttaaagt atttttaatc tgataaattc cgcttttcat aaatacctct 88680 ttgaatatag aagtatttat taaagggcag tcctacaatt tagcacggga ttgtctacta 88740 gagagtttcc ccgtttagat agattacaag tataagtcac cttatactca ggcctcaatt 88800 aacccaagaa aacatctacc gaacgttgat accactgcaa atccaaatag ccattacgca 88860 cattaaattg ataaaacata tgacaaggcg gtaatgccat ctgcttgagt tcagctggat 88920 tccatgcaga aacaatttga cgcctatcat ttggcagttt tttaatacga tcaataactt 88980 ctataatttg gtctacacca ccaaaatcac gccactgttt tccataaatt ggaccaagtt 89040 caccgctatg gtatcctaaa tcttttgctt gattttcgta attttcatcc cagactgttt 89100 tgccttggat taatgaatca tgctgaatta atcgtaaatc attgacattt gtgcttcctg 89160 ataaaaacca tattaactca gcaatgcaag ctttccaggc gagcttctta gttgttaccg 89220 caggaaaacc tttagttaaa tcccagcgta atttagtacc gaacaaagca attgttcctg 89280 tgcctgtacg atcatcggtt tcataaccat tttcaaaaat gcctttaatt aaatcttggt 89340 attgtttcat ttatatactg attccgtaag ggttgttact tcatctattt tataccaatg 89400 cgtttcaacc atttcacgct tgcttatatc atcaagaaaa cttgcatcta attgaacagt 89460 tgaattaaca cgatgccttt taacaatacg agaaacaact acttcatctg cataaggtaa 89520 tgcagcatat aacagagcgg gtccgccaat tacacttact ttagaattct ggtcaagcat 89580 agcctcgaat ggtgcattag ggcttgacac ttgaatttca ccgccagaaa tgtaatctat 89640 atattgctcc caagtaatat agaaatgtgc taaatcgcca tctttagtta caggataatc 89700 acgctcaagg tcacacacta caatatgtct acgaccagga agtaatgtag gcaatgactg 89760 gaacgtttta gcacccataa tcataattgt gccttcagtg cgaactttaa aattctggag 89820 gtccttttta actcgccccc atggtaaacc atcacctaaa ccgaatgcta attcattaaa 89880 gccttcgacg gttttagttg gagaataagc gaataccaat ttaatcatta cgcaaagccc 89940 ctttcaagaa accattcagt ggctttatta gcatcaaaga ataattcttc atatgtcttt 90000 tctttgtttt caaaaactgt cacacaaaca cgttgacatt ctccacagta ttcttctgac 90060 atacgcaaag catcagaaaa catttcatta aattcactta aatcaggatt atgcaatgcg 90120 ttaaaaattg cataatcgaa ttcatcattc ataaattcaa atacaaaaat catattattt 90180 tccttaaaca gactttttca caattttcca atcagcttta aactgttcaa cgtcagaatg 90240 gtaaatccag aatcctgcgc tttctccgtc ttcataaaga ggacatccat cgcattcatc 90300 ttcccacccc atatcacgta aaagatgttc agctttttca acaagttcag aatctttacc 90360 gatgatatta aaataccatt tacctctaac ttctgaatct ttgatgctct ggcgttgtaa 90420 tctcatttta ttctcctcag tagttgatag ggtaatagta tcacactact accctgttgt 90480 aaacaattat ttttgaattt tatcgagcca cttaccaagc ttaatcattt ctttagtagc 90540 cttttccata cttctgaact taaccaatag aggatatgta tcgacaccca taactaaact 90600 ggttacaaga ctgtgttcac ccacaagcca taacgaatac gtttgaatat cgagtccgta 90660 atttctgtct ttatggaccc gtacacccat cacttcaaat ttctcactag ctttttctac 90720 cgcatccagg aaatcatctt tagtcatatt aggccttaaa agtttttcgc aaaagttcaa 90780 tgatttcgtc tacattattt tcgtcaacaa tgcagtgaat ttttgttacg ccagaaacct 90840 tgtctttgac ttcatcttct tcagaagtcg gttctttata ttcgcggaaa caataaaact 90900 cttcttcact aagttcaaaa taatcatcac ccataccatc atcattatag atttcaccat 90960 tggcgcaaat gatttcggtt acataatcaa atccatctaa acttgatatt gatttaactt 91020 caaaccaacc gccattttct tgaatgatgc cgaccatact agcatttgat gaactaatat 91080 caatgaaaga tttaatacgg tgtggattta actcatattt tttgccgatt tccatttttg 91140 attttcctca ttttaatagg ggcttgatag ccccttgata attattgttc aatcaatccc 91200 atgtaaaatt ctgcgtcttc agaatccatg ccatcacaat attcattagc cataaagagg 91260 gtgaggtctt caagaggacc tttaataacg atttgaatac tccaaaactt agaatcttgc 91320 acgcttgtga tactaagttc aggataacga ttacgaataa tttcttcaat atattcaaaa 91380 tcaacgatgt caatatcaac tttagccata ttattttcct ctttaatcat cagcagtatt 91440 gccgatagtt gtatcgtacc acggaagaac ggggatgtaa accgttttgt gaaaaaattt 91500 ttgaaataaa aaaggggacc tctagggtcc ccaattaatt agtaatataa tctattaaag 91560 gtcattcaaa aggtcatcca ggtccgtgtc atcagcacta gatgaactgc cagagcttga 91620 gctcataaaa tcatcttcag tttttgtttt gaagtcatca acattgaatg catccaaatc 91680 atcagcaact ttatcagctt tcttagcggc agttgctgcg gcaccaccca tagcagcagt 91740 tcccataact tgactgaact tagtgctcag ttcttcaaac gatttgaatt tatctttaga 91800 agtcatttca gaaaggtcaa ccatttgttc gaacagttct ttctggaaag attcatcatc 91860 aatgtttgga atcgcagatt gattcaggaa tttagattcg tcgtagttac taaaaccaga 91920 aacttgttta actttcagta caaagttagc accttcccac gggcaagtta catcaaccgg 91980 agtttcaccc atttcaacat caactgcaat cattgcattg attttatccc agattttctt 92040 accgaaacgg tatttaaata ctttaccttc attttctgga gcagctgggt cttttactac 92100 aagaatgtta gcccagtaag aagttttacg tttaacaaga ccgtactctt tattgtcagt 92160 gttgtacaaa tcatttttac tgatgtactg acatactgga caagaatcgt aatcaccgtg 92220 ggtagatgaa catgtttcaa tataccattt accatttttc ttgaaaccgt gatttacaag 92280 aattgcgaat ggtgcttgtt catcattttt agacggaaga aaacgaatta ctgcttgacc 92340 gttacccgca ttatcgagtt tcagtttcca ctcgccttta tcttcagaag aaaaaccttt 92400 attgccattc agtttagcca tttgtgcagc aagttcagca gtagatttac gtttaaacat 92460 tttatttcct tttaatttaa tttaatttaa tttaattaac agttggtgct atgacgatgt 92520 atgacctcat agctggtcag tgagataatt ataatctatt tataataagc aattaatact 92580 tacaagattt cacagtttca ataaaaactt ttttagcttc ctgtgaatca atatttaaaa 92640 tttttctata agcctttaac tttatagaat aattattcca gactaaatta tcagtctgtt 92700 catcgtgttt atcaattata tttaaaaatg aatcaagcaa gataaacgtc tcaaacgaaa 92760 ttatgttcga ttgcagaagt ttaaaaatat aacttgattg aacttttgga ttatattcaa 92820 aaatttcttt aaaagcagaa acttcaactt ttttactgaa atagtaaatg ttgcgaatat 92880 cttcttcaaa cttaaattta atttgcttta agcgtccgat atattcacga taaaacacaa 92940 gtgcatcagc gtcagagatg tcaccaatcc aagcatcttg gttagcaacc aaattactta 93000 taaagattaa agcaagttcc tttaatttat atttttctga taacttctga aaaaaatact 93060 tatcccttcg cttttgataa gcggcatcag acacccgcat gcaccaatta tacttaatta 93120 catcatactt tccattcata tgctgtttta tcattaagta taatttataa actgatttac 93180 catcaatgta tctttcacca ccagcaggca tgcggagttt aatcatagta gaaaatctaa 93240 tgtattagtt ttttcacaac gaacaacaga aggacgtaaa agattttcgt caatagcttc 93300 tgactgaatt ttttcaatta tacccgaagg aataaattta gcaaattgag tttcaggaat 93360 agaattttct tccaagaatg ctgttgtagc ttcaagataa ctcattccaa actcttctac 93420 cattttttca ataataaatc cattttcttg acgatcaaga agctttgcta tttcatcctt 93480 ttctttcttg attgaaagtt ctttttctga aagaccggtc tcatcgaccg gacgaatgtc 93540 atttagagaa aactgtgtca taaagttcaa ctacctcttc agtttcagct tcaaacacat 93600 cacgattatc tttatgatac aaagctaata gacgattaaa catcttacca tcaacgccaa 93660 gttcatcttt ggcacgaatt cgaatatctt taatcagttc attataaccg gaaattttca 93720 gtttatgatc agatgcttct ttaataaatt tagccaagtc ttcgccatgg atagcttcat 93780 caaattcaac catttctttt ttagccatta ttcacctcaa aattcattaa tgctattagt 93840 taatttagaa agacccgctt ttacaaaata tgaataaatt tttccacgcg gtggtaattt 93900 atatgaatta tagtaattca caatgtttga agcaatatta tcaggaatat aatcaaaatc 93960 aattagaact aaattttctt tataccgatt atattcagat tctgtgagaa gcaccttagc 94020 ttgctcacgg tcattagcaa tagcttcaac gattgaagtt ttcattgaag gagttcgttc 94080 accttcaact ttggtaaacc aaaagtcaga tcgtacttta actgaagcaa cgttatcctt 94140 tttatcgcct ttaaggattt tagtcataca gtcaatttca gcagaaccgc ttttaatttt 94200 aacccatttc ttgtgcatcg gtgaccattg cttaacattt ggatatttgt gaagttgagt 94260 aaagtcacca tcagatgaaa tgatcaaaat cttatgtcct tctaaagaga actttttaac 94320 aagaacagca atatggtcat ctgcttcata cttatcaata tccataacaa tgtatggcat 94380 ataagctttc aattcatcta taactttatg actggattca aaataacctt cccagtccca 94440 agtagattct tctcgtgctt ttccacggtt tttcttataa taataagcaa aatcacgacg 94500 ccaatatcca gatttcgcgt tatcaataca cagtacaatt ttagtgtatc caagagtttt 94560 tgcttttttg acattaaact taattgagtt caatatcaaa tgacgaacca tcgataaatt 94620 aattttttct ttatctggga agtttactaa agcggttgaa agcgcaatct gactaaagtc 94680 aattaagcaa attccttctt tgtaatcttc atccagcatc atttctaaat ccatatgaac 94740 ctcgttcaat tagtgagatt tctattatat actatccaaa tcttaaagta aacaagtata 94800 aatacttatt attgaaaaca caataggagc ccgggagaat ggccgagatt aaaagaaagt 94860 tcagagcaga agatggtctg gacgcaggtg gcgataaaat aatcaacgta gctttagctg 94920 atcgtaccgt aggaactgac ggtgttaacg ttgattactt aattcaagaa aacacagttc 94980 aacaatatga tccaactcgt ggatatttaa aagattttgt aatcatttat gataaccgct 95040 tttgggctgc tataaatgat attccaaaac cagcaggagc ttttaatagc gtacgttgga 95100 gagcattacg tactgatgct aattggacaa ctgtttcatc aggaccttat caattaaagt 95160 caggcgaatc aatttcagtt gatactgcag ctggtaatga cattacattt actttaccat 95220 cttctccaat tgatggagat actatcgttc ttcaagatat tggtggaaaa cctggtgtta 95280 accaagtttt aattgtagct ccagtgcaaa gtattgtaaa ctttagaggt gaacaggtac 95340 gttcagtact aatgactcat ccaaagtcac agctagtttt aatttttagt aatcgtctgt 95400 ggcaaatgta tgtcgctgat tatagtagag aagctgtagt tgtaacgcct gcgagtctct 95460 atcaggcgca atcaaacgat tttatcgtac gtagatttac ttctgctgca ccaattaatg 95520 ttaaacttcc aagatttgct aatcatggcg atattattaa tttcgtcgat ttagataaac 95580 taaatccgct ttatcataca attgttacta catacgatga aacgacttca atacaagaag 95640 ttggaactca ttccattgaa ggccgtacaa cgattgacgg tttcttgatg tttgatgata 95700 atgagaaatt gtggagattg tttgacgggg atagtaaagc gcgtttacgc attataacga 95760 ctaattctaa tattcgtcca aatgaagaag ttatggtatt tggtgcgaat aacggaacag 95820 ctcagacaat tgaacttcag cttccgactg atatttctgt tggtgatact gttaaaattt 95880 ccatgaatta catgagaaaa ggccaaacag ttaaaatcaa agctgccggt gaagataaaa 95940 ttgcttcttc agttcaattg ctgcaattcc caaaacgctc agaatatcca cctgaagctg 96000 aatgggtgac tgttcaagaa ttagttttta acggcgaaac taattatgtt ccagttttac 96060 agcttgctta tatagaagat tctgatggaa aatattgggt tgtacaacaa aacgttccaa 96120 cagttgaaag agtagactct ttaaatgatt ctactagagc aagattaggc gtaattgctt 96180 tagctacaca agcccaagct aacgtcgatt tagaaaattc tccacaaaaa gaattagcaa 96240 ttactccaga aacattagct aaccgtactg ctacagaaac tcgtagaggt atcgcaagaa 96300 tagcaactac tgctcaagta aatcagaaca ctacattctc ttttgctgat gaccttatca 96360 tcactcctaa aaagctgaat gaaagaactg ctacagaaac tcgcagaggt gttgctgaaa 96420 ttgctacgca gcaggaaact aatacaggta ctgatgatac tacaatcatc actcctaaaa 96480 agcttcaagc tcgtcaaggt tctgaaacat tatcgggtat tgtaactttt gtatctactg 96540 caggagctac tccagcctct agtcgtgaat taaatggtac aaatgtttat aataaaaata 96600 ctaataattt agttgtttcg cctaaagcac tggatcagta taaagctact ccaacgcaac 96660 aaggtgcagt aattttagca gttgaaagtg aagtaattgc tggacaaagc caagaaggat 96720 gggcaaatgc ggttgtaacg ccagaaacgt tacataaaaa gacatcaact gatgcaagaa 96780 ttggtttaat tgaaattgct acgcaaagtg aagttaatac aggaactgat tatactcgtg 96840 cagtcactcc taaaacttta aatgaccgta gagcaactga aagtttaagt ggtatagctg 96900 aaattgctac gcaagttgaa ttcgacgcag gcgtcgacga tactcgtatc tctacaccat 96960 taaaaattaa aactagattt aatagtactg atcgtacttc tgttgttgct ctatctggat 97020 tagttgaatc aggaactctc tgggaccatt atacccttaa tattcttgaa gcaaatgaga 97080 cacaacgtgg tacacttcgt gtagctacac aagttgaagc tgctgcagga aaattagata 97140 atgttttaat aactcctaaa aagcttttag gtactaaatc taccgaatcg caagaaggtg 97200 ttattaaagt tgcaactcag tctgaaaccg tgactggaac gtcagcaaat actgctgtat 97260 ctccaaaaaa tttaaaatgg attgtgcaga gtgaacctac ttgggcagcc actccagcca 97320 taagaggatt tgttaaaact tcatccggtt caattacatt cgttggtaat gatacagctg 97380 gttctacgca ggacttagag ctatacgaga aaaatagtta tgcagtatca ccatatgaat 97440 taaatcgcgt attagcaaat tatttgccat taaaagcaaa agctgtagat agtaatttat 97500 tagatggtct agattcgctc cagttcattc gtagggacat tgcacaaaca gttaatggtt 97560 cactaacctt aacccaacaa acgaatctga gtgcccctct tgtatcatct agtactgcta 97620 cattcggtgg atcagtttca gcaaatagta cactaaccat ttctaatact gatggaacag 97680 caactcgtct gatttttgag aaaggacctc aaactggaac gaacccggct caaacgatga 97740 cagtcagcgt gtgggggaat caatttagtg gggaatcaaa cacaacacgt tctaccgtat 97800 ttgaagttag tgatgaaaca tcttatcact tttattctca acgcgataaa gatggtaata 97860 tagcatttag cattaatggt actgtaatgc caataaatgt gaatgcttta ggttctttga 97920 atgcgaatgg cgttgcaaca ttcggtagtt cagttactgc taatggcgaa tttatcagta 97980 aatcgtcgaa tgcttttaga gcaataaatg gaaattacgg attctttatt cgtaacgctg 98040 gtaatgacac ctattttatg ctcactgcag ccggtgacca aactggtgga tttaatgcat 98100 tacgtccatt atcaattaat aatcaatctg gtcaagtaac gattggtgaa agcttaatca 98160 ttgccaaagg tgctactata aattcaggcg gtttgactgt taactcgaga attcgttctc 98220 agggtactaa aacatctgat ttatacaccc gtgcaccaac atctgaaact gtaggattct 98280 ggtcaattga tattaacgat tcagccactt ataaccagtt cccgggttat tttaaaatgg 98340 ttgaaaaaac taatgaagtg actggacttc catacttaga acgtggtgaa gaggttaaat 98400 ctcctggtac attgactcag tttggtaata cacttgattc gctttaccaa gattggatta 98460 cttatccaac gacgccagaa gcgcgtacca ctcgctggac acgtacatgg cagaaaacca 98520 aaaactcttg gtcaagtttt gttcaggtat ttgatggagg taaccctcca caaccatctg 98580 atatcggtgc tttaccatct gataatgcta taatgggtaa tcttactatt cgtgatttct 98640 tacgaattgg taatgttcgc attattcctg acccagtgaa taaaacggtt aaatttgaat 98700 gggttgaata agaggtatta tggaaaaatt tatggcagag tttggacaag gatatgtcca 98760 aacgccattt ttatcggaaa gcaattcagt aagatataaa ataagcatag cgggttcttg 98820 cccgctttct acagcaggac catacgttaa atttcaggat aatcctgtcg gaagtcaaac 98880 atttagcgca ggacttcatt taagagtttt tgacccttcc accggagcat tagttgatag 98940 taagtcatat gctttttcga cttcaaatga tactacatca gctgcttttg ttagtttcat 99000 gaattctatt tcaagcaata gacttgttgc tatattaact agcggaaagg ttaattttcc 99060 tcctgaagta gtatcttggt taaggggagc aggaacgtct gcttttccat ctgattctat 99120 attgtcaaga tttgacgtat catatgctgc cttttatact tcttctaaaa gagctattgc 99180 attagaacat gttaaactga gtaatagaaa aagcacagat gattatcaaa ctattttgga 99240 tgttgtattt gacagtttag aagatgtagg agctaccggg tttccaagaa gaacatatga 99300 aagcgttgag cagtttatgt cagcggttgg tggaactaat aacgaaattg cgcgtttacc 99360 aacttcatcc gcgataagta aattatctga ttataattta attcctggcg atgttcttta 99420 ttttaaagca cagttatatg ctgatgccga tttacttgcg cttggaacta caaatatatc 99480 tatccgtttt tatgatgaat cgaatggata tatttcttca acacatgctg agtttactgg 99540 acaagctgag tcatgggaat taaaggaaga ctatgtagtt gttcctgaaa atgcagtagg 99600 atttacgata tatgcacaaa gaactgctca agctggtcaa ggcggcatga gaaatttaag 99660 cttttctgaa gtatcaagaa atggcggaat ttcaaaacct gccgaatttg gcgtcaatgg 99720 tattcgagtt aattatgtct gtgaatctgc ttcacctccg gatataatgg tacttcctac 99780 acaagcatcg tctaaaactg gtaaagtgtt tggacaagaa tttagagaag tttaaattga 99840 gggagccttc gggttccctt tttctttata aatactatta aaataaaggg gcatacaatg 99900 gctgatttaa aagtaggttc aacaactgga ggctctgtca tttggcatca aggaaatttt 99960 ccattgaatc cagccggtga cgatgtactc tataaatcat ttaaaatata ttcagaatat 100020 aataaaccac aggcaactga taacgatttc gtttctaaag ctaatggtgg tacgtattta 100080 aataaagtaa tttttaataa aggaatgact gttcctggtg cagggtcagg tgacaatggt 100140 atttttgctg gtcctggtga taatgccacg tatgatacta caaatatgga tattgtttct 100200 tggtatggta ttggttttaa atcatcacaa ggaacagcag gtagaactgt agtaattaac 100260 acacgaaatg gagatattag ctcaaagggc gtaattgaag catcacaaat acgagcaact 100320 tcgttatcac cagtaaataa ttatgacctt acgcggaaag attatgttga tggagcaata 100380 aatattgtta cagcaaacgc aaactctagg gtattacgct ctggagacac tatgacagga 100440 aatttaactg cgccaaacct tttttcacag aatcctgcat ctcaaccctc acatgttcca 100500 cgatttgatc aaattgttat taaggattct gttcaagatt tcggctatta ttaagaggac 100560 ttatggctac tttaaaacaa atacaattta aaagaagcaa aactgcagga gcacgtcctg 100620 ccgcttcagt attagccgaa ggtgaattgg ctataaactt aaaagaccgc gtacttttta 100680 ctaaagacga ccaaggaaat atcattgatc ttggttttgc taagggcggt agcattgacg 100740 ggaatgttat tcatacaggc aattataacc aaactggcga ttatacttta aatggcgtct 100800 tcactcagac tggtaatttt aatttaactg gtattgctcg agtaactcgt gatattattg 100860 ctgctgggca gattatgact gaaggcggag aacttattac aaaaagttca ggaacggcac 100920 acgttcgttt tcatgattcc gccgaccgtg aacgcggtat tattttttct cctgctaatg 100980 acggtttaac tacacaagta gttaacatca gagttcaaga ttacaaagct ggttcagaaa 101040 gcactttcgc ttttaatgga aatggtttgt tttcttcacc agaagttttt gggtggaaat 101100 ctatttcgtc tccacaaatt ctgaccgaca aagttattac aaatgggaag aagacaggcg 101160 attatgatat ctattcatta tcaaataaca ctccaatggc agaaggcgaa acggctatta 101220 accacctccg tgttatgcga aatgctgtag gagcaggtat tttccacgaa gttaatgtta 101280 atgacggaat aacctggtat tccggagatg gcttagacac ttatctttgg tcgtttaact 101340 gggctggtgg attgaaagcc ggacattcta tttctgtagg tcttccaggc ggtcgcaaag 101400 gatattctga attaggaacg gcctcaattg ctcttggtga taatgatacc ggatttaagt 101460 ggcatcagga tggatatttc catacagtaa acaatggaac aagaactttc atctacggcc 101520 ctgcggaaac acaaagcctt agaaaaatgg ttatgggtta ttctccggac gggattctta 101580 tgacaacgcc accgacagaa aactatgctc ttgctactgt agtgacatat cacgataata 101640 acgcggttgg agatggtcag actcttttag gatattatca aggcggtaac tatcatcatt 101700 atttccgcgg caagggcact acaaacatta atactcacgg cggtttgtta gttactccag 101760 gcaatattga cgttattggt ggttctgtta atattgatgg tcgtaataat tcttctacgc 101820 tgatgtttag aggtaacaca acaggtagta gttctgtgga taacatgaca atttctgtgt 101880 ggggtaatac atttattaat cctagcgaag gtaatcgcaa aaatgtcatg gaaatttctg 101940 atgcaactag ctggatgagt tatattcaac gaacaactgc aggtaaagtc gaatcggtta 102000 taaatggcac ccagattgtt aatgaaaact tgacagtagt aaaaaatgct acatttgacg 102060 gtacaatcag cgcagccggt gaaatcgcga caaatgctgt aaatggtctt cgcatttgga 102120 acgcagatta tggagccatt tttagacgtt cagaaggcag tcttcatatt attccaactg 102180 cttacggtga aggtaaacac ggcgatatcg gtccacttcg cccgtttagt atggctttag 102240 atactggtaa agttactatt ccagatttac aatcaagtta caatacgttc gcagcaaatg 102300 gctatattaa atttgctggt catggagctg gggctggagg ttatgccgtt caatatgctc 102360 aagcggctcc tattttccag gaaattgatg atgatgctgt aagcaaatat tatcctattg 102420 ttaaacagaa attcttaaac ggtaaagcag tttggtcttt aggtactgaa attaattctg 102480 gtacattcgt tattcatcat ctgaaagaag atggttcaca aggccatacg tctcgtttta 102540 atcaagacgg tactgttaac ttcccaggta atgttctggt cgacggtgat attaacatga 102600 aaggcgtgat gacttttgac gccggacgtt taggatcacg agattatttt aaatttaacc 102660 attggggcga tagcaataac gctcgtgata acatcatcca gttagaagat agtcaaggcg 102720 ctcatttttc cactgaacgt actttagcga caggtgcaat taaaactcgt ttctttggcg 102780 aaacatttac tgatggtaca ttatacctaa atcagatgaa taatagctct gaacgattcc 102840 atatcaataa ttggggaaat tcagaagttg gtcgcgcggc agtgatggaa gtcggtgatt 102900 ccaaaggtta tcacttctat acagaacgca ggacagataa cagtttgacg tttgatgttg 102960 ctggcgcttt taccgtgcat ggatctagcg ggatcactat caaaaactct gctggcgctc 103020 gccacatctg gtttaaagat gatagcgaat cggaaaaggc tgttatctgg gctacagatg 103080 agggtatttt acatatacga aataattatg tgggttcatt tagtcatcac ttccagggtg 103140 caatgattaa agtgggagag cgtgttcctt atgccggaga tcaagggctt attcgcggtg 103200 aagtttctgg tggtgcatat gttgcatgga gagaacgccc tgctggtttg ttgcttgact 103260 gtcaacaaag cgttaatagt gctcatgcca tttggaaagc ggttgattgg gggcgtaact 103320 acatcgctgc tctggacgtt cattgtcccg gtgatagtaa taatactgcg gcagcggttc 103380 tccatgttca gtctgctgat tatcaattcc atgcaagtgg agaatttcat gccactggta 103440 acggaaactt taacgatgtt tatattcgat cagaccgtcg cctcaaagaa aacatcgaag 103500 attatatagg aaatgcaact gatttaatcg gtaaactgaa agttaaaacc tacgataaag 103560 ttaaatcatt atccgaccgt gaaattatcg gtcatgagat cggcattatc gcacaggatt 103620 tacaagaaat attaccagaa gcgattaata tttcgaaaat tggcaatctt gataaaccag 103680 acgaagttct gacaatttct aactccgctg tgaatgctct tttaattaag gccattcagg 103740 aaatgagtga agaaattaaa gaattaaaaa cgcctttctt cactaaaatt gctcgcaaaa 103800 ttggtaaata ctttaaattc taataacaag ggcattgccc ctttggagat aaattatggc 103860 agtagttggt gttcctggtt ggattggtag ttcatccgta aatgaaacag gacaacgatg 103920 gatgagtcaa gcggctggtc aattaagatt aggtgttcct tgctggatga gtcaatttgc 103980 aggtcgctca agagaaatta ttcatacact tggagcagac cataacttta atggtcaatg 104040 gttccgagat agatgttttg aggcaggtag tgcacctata gtgtttaata tcacaggaaa 104100 tttggtatca tattctagag atgttccttt attcttcatg tatggagata caccaaatga 104160 atatgttcag ttgaatatta gcggtggagc tcatatgtgg ggcagaggtg gacaaggtgg 104220 atggactcat tctggtggag atggtaatgg tcaacagggt ggacattgta ttcaaaatga 104280 cattggtggt cgattaagaa ttaataatgg tggagtaatt tgtggcggtg gtggcggtgg 104340 tggcggtatc gcttatcgtc ctcactctgg cgcaaggtgg caagatattg gtggcggtgg 104400 aggaagacca tttggcccag gaggaggcgg aggttattcc ggtggcgcag cttcttatga 104460 tggcccagga ggtggttata attatggtat tgctcactct ggccagggtg gtgatgctgg 104520 cgcaaatgga caaaatgcct ggcatgatgg cggtaaagtt ctaaaagttg gagctggtgg 104580 cgctgccgga tatgctgtta taggatcagc tccaacatgg caaaatgttg gagtaatata 104640 tggtccaagg gtataatttg aataaatatc cttaaaagga gggtctatgg cagcacctag 104700 aatatcattt tcgccctctg atattctgtt gggtgttcta gatcgcttgt tcaaagataa 104760 cgctaccggg aaggttcttg cttcccgagt agctgtcgta attcttttat ttatgatggc 104820 gattgtttgg tataggggag atagtttctt tgagtactat aagcaatcaa agtatgaaac 104880 atacagtgaa attattgaaa aggaaagaaa tgcacgcttt gaatctgtcg ccctggaaca 104940 actccagata gttcacatat catctgaggc agactttagt gcggtgtatt ctttccgccc 105000 taaaaactta aactattttg ttgatattat agcatatgaa ggaaaattac cttcaacaat 105060 aagcgaaaaa tcacttggag gatatcctgt tgataaaact atggatgaat atgcagttca 105120 tttaaatgga cgtcattatt attccgactc aaaatttgct tttttaccaa ctaaaaagcc 105180 tactcccgaa ataaactaca tgtacagttg tccatatttt aatttggata atatctatgc 105240 tggaacgata accatgtact ggtatagaaa tgatcatata agtaatgacc gccttgaatc 105300 aatatgtgct caggcggcca gaatattagg aagggctaaa taattatttg ttcgtataca 105360 tctgagata tcgatataca ccctcaaaac cctcgttgaa ttcgtcgatg agggttttct 105420 tatcttcttg agttaattca gaaacaattt tacggaatga attctgattt aactttctac 105480 cttcatgtgt tactccaatc tcattcagaa atgcaataaa attagcacga ttctcaacaa 105540 tatcttctct ggaaaattta atcaaaatag acgcaacagt aataatttca cgaactgcat 105600 caatattttt attcattaac tataccactc aattagttga ctttattata atatcatcag 105660 acacttgatt tgtaaactgg tctgtgttat tttcttcaaa aattttttct acgaattcct 105720 taaacgactc gcgttcctga gctacattat gctcgattac catttcaaga ttatgactca 105780 ttcgaaataa tcttcaattt cgtaatcatg gacataaatc attatagttt ttaatacatc 105840 atcgatactt tttcctggag ctggaattac gtagaaatat cctgcttttg agaggtcttt 105900 ataagttcca attaagaaat cgttattctc aagatgcagt tcttcaacta attcattaac 105960 aattgaatgg tataaatttg gtagaaactt atatagcttt tctagaatat caattttgat 106020 tgtatattga accacagact gagaatcaat aatcatagac cttcccctta tgtttctgtt 106080 tgcgattaga ttctttaaac gctttcttct tatccttatg aacagaagct ttattaaaat 106140 tatgttttgc gactaaattg ttcatagtgc tgaattacct ctctcaaaca tttgcatgtg 106200 aatgaaaact ttttagctac accacattca aatatatgtt ctcttaaatc acgtgtgtca 106260 gtatatccca tctcaacaat aaaatgccgt attagatttt tatctttatc attgagagaa 106320 ttaaaataat cggattttga attaatttcc ctggccaaat tgaatcacct tcagttgacg 106380 ttttagttct tttatcattt cttcgttcat cgcaatataa agatcgcgta aagcaggttt 106440 tatcattcca tttattgggg aactaaatgg acatacataa tcttttccta cgagcttttt 106500 agttaattcc atatcacaaa actgaaatgc aggttcatta gcataaattc cccaattagt 106560 tgacatcatt ttattggcat attccaatgc ctggatttga ttcataattc catcaatttg 106620 aaatttttta atattcatta gtaaaggtcc tcagagtaaa gttctttttc actaccgccg 106680 cgttcaatac gtacctgtcc agcgtaagtt gcaataatca ttgcttcttc acgtgtccaa 106740 taattactat attggtcaat aaacccttgg tcatcatcac aaacttgctg agtaactaat 106800 tggggtttaa ctacatctaa aacttcggcc atatctttag aataatgacg agcacccgga 106860 ataataagag ttcgtccatc ttttaattta aaacggttgg ctgcgcaaac aattcgtcgt 106920 tgatactttt gattttcatc ccaatatgca gtctgccaac agatttcagg aacttctttt 106980 aaaatatctt cttctgtgca tttataacca tgcgctttaa atttttcaac aagactttct 107040 ggagtttcac gagataaagg aacattcagc atttttaaac gattaataaa tgggttcatt 107100 taaaccatcc tttaatacgt tgccacaaag ttttctgttg agctttgtta acgccaattg 107160 agcgaataac cggttgagat tcctggaatt ctttataatc agcaaggtaa atttcgtaag 107220 ctgcatctgt aaaggaactt atcgctgcca tgaaattatt gcgaatacct actggagcat 107280 ctttactttc acgaataatc atgtatttac cagtcttaat ctttacaata gttccaagat 107340 aagctccatg gtaccaaata tcccaaccct cttgagtagg ttctgcacaa cgacgaagtt 107400 cattgataat ttctaacttg ttcattattt attcctcaca gttcagatgc tacggtaatt 107460 actgcttcaa tgttttctgc tgagcgttta atgtcaagat acacattacc gtttttagcg 107520 attttacatg acattccgat atcaataaat ttctgaatat gatgttccat cattttgtat 107580 ccaaaaattc gcatatttcc attgttgtta atttcaaaat tacgaattcc gtgagtgcgt 107640 ttttctaaaa tagcgagata gttactacga taagtttcaa cctttttaag aacaaatcca 107700 ttttcatcta aaagttttaa catgaagtct ttatcttctt ccatatcaga agtaatctcg 107760 cgagctttac gagttgctcg ttttttcaac agttcaggag cgttttcctg cgcgtataaa 107820 gttgctgcat ttgaaataat atcctgagct tcaccagtaa tgattaatcc atcaccagat 107880 ttctctacca ggcctttttt aatcaatacc ccaatattac tattaactac tgcattacct 107940 aaatctggat gcacctcacg aacttctgca gctgtaatga aatctttctt agcaatggta 108000 attaaaatcg cagcagtttt ttcattcaga acatcgttag aagctttgat gatgtaagtt 108060 actttagaca ttttctaatc tccgtaattc tgtatcagta gttgatagtt gtatagtacc 108120 acagtatgct ttggttgtaa accgttttgt gaaaaaattt taaaataaaa aagggagagc 108180 cgaggctctc cctaaaatta ctgcatgact gtgataacta tcatgataac acgttgaatt 108240 ccgaacgcaa gaagacctcc tgctacagct ggaacaacac ctaaacccgc cagtaaaatg 108300 ccaccggata ctaatgcagc gcttgtgata ccaatgaatg gactcatttg atttcctcta 108360 aatctttggt gtattctgta actacatcag tagttttcca atattcgttt tcttctttct 108420 tagctttagc ttcttcagca agtttctttg cttcatcaga agtcatatga aaaatattca 108480 ttccaactag tttatcaaca taagaagaat acatatcaat tttagaaagt tcttcggtca 108540 gttctttgcg agttttacct tgcacaacaa tttcacctga aattactttc ttaatgaaat 108600 gtgccttggc aaaggctaaa cgaaatgctg attcagtttc tttgattttg ttatcaattc 108660 gtttttgaac ataagtttta cgaacttcaa cgaagtcttt gattaaatca actacgttgt 108720 cgtaaacttg cagttttcct ttctcattaa tgacggtaat attctgagaa cgacgttcaa 108780 tcaatccgaa gtctttcaca atttttgcat gacgttcttc ttcattatcg ctcaaagagt 108840 attctttgcg gaatttaact ttgaatccaa acccatgctc accacaagca tcatcccatg 108900 taatgaagcc tttatcttca agtgggtcta agattttact cacataagtt tcacgatcat 108960 acttatacgg aatctcagtg atatgcattt gagttcgtga agtaaactta tatgttccac 109020 gaatttcata ttgcccatca atttcaacga cttcaccacg aaattctggg aattctacct 109080 tcggtttagt tactttcttt ccttgaagag cttgcagtac agctttcttg acagaagaaa 109140 cactatgagg aagaatgtaa gttgcataac cagttgcaat accggaaacg ccattaagaa 109200 gaacagtagg aataacaggc aaatagaaag caggaggaat gtgttcttta tcttgatgta 109260 ccggagcata ttcagtatct ttatatacgt tatagaaatt tttacttaca cgagcaaaaa 109320 tataacgact tgctgctgct ttttgaacgg tacgagaacc aaagtttcct tgaccgtcta 109380 acagaggaaa gttattattc caagtattag ccatcaaagc ccccgcgtct tgcgcagagt 109440 tttcaccatg atgatatcca aggtcagcta caccacctgc aatagaagcg agtttgtgaa 109500 acttatcttt atttcctcgc gccaaatcaa gagctcgagc aataacaaat cgttgaactg 109560 gcttaaatcc atcaatcata tttggaatag cacgattttc aaccgtgtac atagcataag 109620 ccagtgcttc attatcaatg atacttttta aatcgcgatt attcagttgc ataaatttac 109680 catactagtg aatgtagtgc cataataaca tcagaaatga aaagcacgac ttgaattaat 109740 ccgaacatta ctccataata tagtgctacc aataaagcag caagggctac cgagtagccc 109800 aagattttct taatcattag tagataacaa cacaaatgtt aaatatgcac acataccctg 109860 agctaaagct tgcgaaaaca cactgctggc atcaatacagi atagttaaaa cacatgctac 109920 tatccaacaa ataaatgaaa taactcctaa taattttgcg atattcatat tttcctcact 109980 ggcgtccgaa gacgcctttg gttttaagat tgttacgata gaactgcatc acatgttcgt 110040 tatggaaatt actcattaat atgcctgcaa aacaaattta aagttatcag ccaacatacg 110100 gttcatttct tcaagtgttt gatactcaga atgatgatta cgagtaaacg ctaaagctaa 110160 ctgtcctttt ccaaatcccg tcgtcaaagg tttcatctta gaagcaggca gataaaatac 110220 cgtgtatgga acattgttat ttgcaatagt acgcgcaagc tgagaccggc gttgacgaat 110280 atgacttaga actgcgctga atccttgctt agatcgctga ttacctacat aaaatcgtgc 110340 agacacacat ggattactaa atggacgacc atctaattta cttactaaaa aataaaatcc 110400 aggtttagat aaaatatctt tatgcggagt tcccaaaaac cactcaccac ccttgattgt 110460 accaataaca gtagcgcctg cattgttcag atcagtaaca gtcatatatt tcatgttatt 110520 ttcctctaat tattttctac tccaaggccg catgaataca cacggccatt aaattactcg 110580 tcgcagtcga cgctcaattc ccagaactct tctacagtat aagtttcagt atcattttca 110640 atacagaaac gttcattact gttatttgct aaagtagcat taactgtcgg tttctcgtta 110700 gtgctcttaa gaggtgaaat acgaattaac tgatcaccgt tatctaaaca gaaaatttca 110760 ccaactttta catctttaaa aattttcata attcacctca gggagtataa aatccaaatg 110820 cagttgttga ccatcccatc caatatggga aatttgcacc aatgtaaaac ataagaatat 110880 aaaaccaaat gtttagtaaa ttcatcattt tacaccattc caaattgttt caaccacaga 110940 ttttaaacca ttttgatgaa tatcaattcc gactactgtc atcaaataga ttccaactac 111000 aactgaaccc aaggcgaaaa tcaacatgaa aatgaataaa gccggaaaaa tattatcgaa 111060 aaaccattcc ataaatgtaa aagcactgcg tttacgcttc atattttcct cacataaatc 111120 caaagtaagc gtttaataca tcaatcatta aaacgattgg gaatatactc aaaactacta 111180 gtattacac tacattccat atagctttaa caatcttttt cattttctgt tcctccgtag 111240 ttgataggat aataatacca cagaggaaca gtcttgtaaa caactttttt aaaaatattc 111300 gtaataaatg tgaataccaa tcactactgc cgaaacttgc gcaacccacc acgcacacgc 111360 aataagtaca gaattcaaaa ttttcataat aacctcatca caaaagtaaa tgttaaacaa 111420 attattggaa tactaattaa ccaaacaaaa caccaccata atgaactcat agttcaatct 111480 caatgatttc aagattattt tctttaatag ctttctttaa atcatcgtaa ataagaactt 111540 cccaagaatt gtttaaatca ccattcaaca aacgctcttg ttgcaattta tcagtaagat 111600 atggttggtc tgattcatat ttagacaatc ccaatgaaat aaatgatgtt gcatcgtcaa 111660 tttcagaata ttgtacataa acaaattcac ctgtgatttt atgtttaaca taaaagaatt 111720 taaatttcat ttttactcct ccgtagctga tagttgtata gtaccacagt ccttgtggta 111780 tgtaaactgt tttgtgaaaa tttttaaatg gaaagatacc atccgttgta gttgcttttt 111840 cttacaacct tacgaaggtc ttctctatca ccaatgaact tcggagtgta ctggatgaca 111900 cctggatgaa tttctttagt gttgaatata attatacagt cagcgacttg atgatttaga 111960 atgggcccta gatttattcc agaaccgtat ggatactctc cgctgcatcc ggttgttacc 112020 gaaatccaac gtgagtcagt ttgatgtgtc ttaacttcta cacgaagccc gcagtatttt 112080 ggatgcgcca gtacatccca cgcatatgta tacgggtcat taacatcctc ttggcctttg 112140 ttaacatacc cgctcagcca atctgctaca aaaaactctg catacacagc gatacggcat 112200 ctttcaataa cttctgcttt atcttggttc gggttttgtt ttaaagagta tcttgctgta 112260 tcagcaattt tgaccttcat ttcactagtc aagtcactgt tcgatagggt aaatgtcgga 112320 atctgaaata gtctctgtaa acccggattc gttttctgca tttagacttt cctttttacc 112380 gctgagataa gcgttatata ctttaagagt gccgtaataa attcggtcat tttcatctaa 112440 agactcacgg tcaagttcat cgagttcctt tttatccatg actataatat cattgcagta 112500 aagaaaccca agtttttcgt gaccaaactc aaatttattg cagtacacaa tattagcgtg 112560 atgatttccg tgcagtttaa tctcttttat gtcggaatca ccgatattca tacaataaat 112620 cataattttt ccttaaaaca aaagggccga agccccttat tttatttgaa ttgtgcaatt 112680 cttttctcta gacattcagc ataagatttc attgagatga actgtgaaag cagcagttct 112740 tgctcaactg cactaaccgt tagaaacttt gtgctttcta aaaatttact aagtgcatta 112800 attttgagca ttaattgatc gtattcttct tttactcgtg cttgataacc taacataatt 112860 ttccttagtt aagggccgaa gcccttattt aaattgttca gtaacgtctt caactacttc 112920 gtattggcag gtacgcattt tagcgtcgtt gtaatcaatc ggaattgata ctacatcgcg 112980 cggatgcact ttaactttta caactcgact ggttgaacta ctaaagtgac gaatataaga 113040 tttagaacac acatgcagac cacgagaaca agtttgtgta tcatcgtcat tcacacgagt 113100 acgtggcatt ttaactactt taccaggact attatcaaaa gtatttgaat gacagtcaaa 113160 gtaattactg cgaactactt tccaagcata gaagtaacca tcttctgtaa tttcaatatc 113220 atttgctacc aagaaatcaa agagtcgaga taccgctttt tggcttgggt tttccagcag 113280 attttccaag aacggaaaat aaaattcaaa gttttcgcct ttttccatcg aatcgagaat 113340 acgatcaact aaaccagacc gtaattcgat attttgatag aacaagcttc caccttcaat 113400 tcgaacatca ccggaaatat atttttcaac agcgcgacga acgttaattt tttgtgccgc 113460 ttcttccaac ttatccgcta caagcagatt aagaatttcc tggaagtttg aatgagtatt 113520 aggagttgcg ttataagtta caccgtcaac agtaattgaa atgaattttt tagatgcatt 113580 ccaaataatg tcagatttag caactggagc aataactgca tcgctattaa ctttaactgt 113640 aataccaccg ctaatagtaa ctttagggtg tttagcttct tcagcatttt tcaaaacacg 113700 acggattgtg tcaaccgata caccttgcca atcagccaat tcctgttggg tgtaattacc 113760 acttgaatac agtttaacaa tttcagcttg ttcgtttttg gtcaggcatt taatattgta 113820 cataattttc cttattaggc cgcaagggcc ttcatagttt tagcgatttg agaaacttca 113880 tcatcactta aagagttgcg atatccgatg aagtcggaaa caatacggaa tttcttggta 113940 aactcagcaa ccattttatc actgtttttt gaagcattat ttgataatac atcaaaaaga 114000 ttagttactg tccagatgtc atgaccgatg gtatcttttc caccattaaa atatacaccc 114060 tgtaatgaac taaccatatt agcgagtcgt gtatattctt cagaaacttc atctacactg 114120 aagtacttca tcataaaatc tagctcagga tacttgataa ttttatcaat atatcgttta 114180 gctgaacttg aataacctac atacttatca taatctacat catcaaaagc atctacatat 114240 aaatcacgca aagcttcaaa aatacattgg cactgaccga gttcttttac ctttttctgc 114300 aaaagcggac gaataacata aaattcatta atgccaataa gattagccat acgaatcaaa 114360 atattcatag atggatgaca aagagatgta gtaccatcca tagagaaaat atcagaacga 114420 tgcatatacg ctacataacc agtaatttca tctgcttctg atgtgagcgt aaatagttcc 114480 tttttttccc agcgcccgtc tttaatttca aacttaaatg ctgtagcagc tttaggacga 114540 ggagctttac ttttaactac ctttggaata taacttttaa ctaaagcttc aatttctgac 114600 aaataatgaa tgttaacttc atcactttca aacatcgcca taatatcagg gagtaaatca 114660 atctgcgatt ctacttctgg attaataaac agaagacgct cattgtgatg aatatttaaa 114720 gtgttattaa attcactatc atctaacgca tgtgctaatc cacgaacaat attaacacga 114780 tttttaatat catcaataac gatattaatt tttgttgtat taataccaaa cagacgataa 114840 cttgatgcga cggctgaagt ttcatgactt tgcttaatgc gtttcagtcg agggtcaaga 114900 tttacttcat acacaacccc tgcattgcat aacttactgt caggttcaaa catgctctgc 114960 atctttttat atgacagatt tttagtcgtg aatttgactg aattactaat catataatct 115020 cgagcagaat accccatctt catcaattca cggtatgtgt gacgaggaga tgtagattct 115080 ttaaatcgtt ttacatcttc attaaatgct ttctcactaa gctctttaac acgctcaata 115140 atatttttac gggtacgatc atctagtgaa agagcttcac gtgatggagc aatatcaagt 115200 gaacccattg gaaacttaat gtaattcact tcattgcgaa tgcttagcca gttacggtct 115260 ctaataacac catcaatagg ataaacaata ccgccataga tagcatataa tccaccaqa 115320 tctggccagt atctttctgg atttacgccg taatagtcat caaaatcagg aaaataatca 115380 atttcacggt caagaccatt aatgatagcc aaatctttga atggtcgcat gatataagaa 115440 acttcataag caaagtttct aaagtctttt tcttcaactg gaactacgat ttcaatacca 115500 gttttatcgt ttggacccat ttcttttacg aatgtaggtt taatctgtgg gccatcacca 115560 tccatgtaag ctacataacc acgaatttca cctttatgat acgaagtaat actaaacgta 115620 tcagtataac taaacggaga tttagaacct aaaccaaatc cgccaatgaa atcgttagat 115680 tcagccttag atgaactgaa gtatgaatta tacaaaccag gagaattatc atcaccctga 115740 atatcaaaat cactcatacc cggaccaaaa tctcggcaaa caaatcgtgg atctaaacgt 115800 ccaggaactt gaatgataaa tttttcagga tttccattga gagcatgggc atcaatcatg 115860 ttggtaatca attcacggac tactgcgcga atcttgtttg tatacaaatc agacgacaga 115920 attttaaata ctttaggaga tgctgtgatg ctaaatgctt ttgatttaga accattacca 115980 agaattgttt ctttttcagt ggtgataatc ataatttcct cattaattca tattacgctt 116040 aataacttca gcaacttcta gtagttcgtc tttagttgcg gtgtcggatt gaattttatc 116100 tctaatatct ttaaagcggt ttttaaattc ttcggcttct cccatatcga aaaagcgttg 116160 aatgattcta tattctcgat gaactgcttt atcaaaaagt tctaaattta ctttatatga 116220 tttcatttca atatcctcat ttgcccaatt aattatacca catccttgtg gtaaagtaaa 116280 ctactggctc atccattctt tacgaaggtc agcattatct cccatgagca tttcaaaaag 116340 ctctttccag ttctcaggaa gtttaacaac atcatatact ggattttgaa tcatctcacg 116400 atattcagat ttttccaaag agccaagtcc cttaatataa cggatgctat gtttaggtag 116460 agcatctttg gcactctcat attcagcgac tgtataaaac cattcttgtt ttttaccgac 116520 ctgagcgatg attacaggag ttttgacaaa gcgaattctt ccttgttcaa acagttctgg 116580 ccaattacta aaaaatccga gcagagaagg ataaatgctt cctagaccat catggtcagc 116640 atcggtcata attgcaatat tatgataatt taagttttcg gctttttcac caagaactaa 116700 tccagtgatt gcgcaaatat caaacagttc tttgttttta agcatatcag catatgacat 116760 accccaactg ttgagaactt taccacgtaa tggataacca ccatgaagtt ctttatcacg 116820 aacatcaata agatatccga tagcagaatc accctcagtc aagaaaagag tagtgtcagc 116880 atctttaccg caaagattcg ctttaatatg tttatgaacc ttagctttag aagccttttt 116940 agctgcttta gtttctgctg ctttttctgc tgccaattta cgagccaagg cagcttcaat 117000 aattggcatt aaaattgctt cattatttaa aatagcacgt gaaatctttt tagcatcaag 117060 ctgaatatga ctgcggattt caccaaatgg agaagtcaaa cgctctttag tttgagaatc 117120 aaatcgcatg tttttcatat cacgaacaaa cataacgata gtcaaacatt ctttaacacg 117180 tgctttagtt acatcaattt tgaacttacg tttgatttgt ggaataaggt cttcacaaat 117240 atcatccata acacagtcaa tgtgatgacc accattctta gtatgaatgt tattgacgta 117300 tgttaattga cgaaaaccat ctggtgaacg accaaccgca atagaacaat tttcttgttc 117360 ttgaacgata gcatgttcat catactgtcg tgcatatttc ttaaaattgc cctgaacctt 117420 tttaccatta aaggtaaatt gaatatcagg ataaactact gcaagtgtct ggagacgatc 117480 tagtgtaatg tcaagataaa cttgggacag ctcattagtt tcaaatgaca taaaatcagg 117540 aatgaaagta acacgggttc ctttccattt tccaggaata gtttcccatg atttattttc 117600 catgccattt gaacaacgaa ctacaatatt attttgacca tcgccagttt caccgacaaa 117660 catcacagaa aaaatgttag ttaaactaga gccaacaccg ttcataccgc cagtgacgcg 117720 ttctttatca tcaccaaagt taccacctgc ttttggaata gtccaggcag caacaggacc 117780 aggaatttct tcaccagtag gtgttttaac catcgcttgt ggaataccac gaccgttatc 117840 ttcaactgtt acttgattgt ttttgatagt aacattaatt ttatttgcga atttaaactt 117900 agtacgaata ccttcatcta ctgagttatc gataatttca tcaataagct taacaagacc 117960 aggtacatac tgaacacttt cccatttacc aaacagaaag cgctcatgca tttcattagc 118020 ggaagagcca atgtacatgc cgctacgctt tttgatatgt tcaatatcgc tcagaatttt 118080 aatttcattc ttaatcatca cttatcctcg tttggtttcg ggaatattat actccggtaa 118140 tcataaagct aaaggcccga aggcctttta tttaaaacgg atagtcgaat ccttgaagaa 118200 tagaccagaa catactgttc cttctacttt ctgcccagta ggtccaacag cacgaaatcc 118260 agtgtgttgg aaatcatttt cagagcaacc gaaccagtta tatccagtga tttcaatatt 118320 agtaaaacca cttgaagaca aaactttggt tgcattatca gcatcagtac atcctactaa 118380 agacactgct aatactaatg ctgcgataga acgattaaca tatttcataa ttacccttta 118440 agtaagtcgt aaaatccacc gttcacatgc ttaggagcgg aaactaaccg aatagcaatc 118500 cgatgacaat caggacatac atcagtatcc ctttcagaaa ttttcttgat tttttcgtat 118560 tcttttgcac agtctttgga ttgacattta taatcataaa gaggcataat tattccttaa 118620 agtgagcttt caacatctga tacaaagacc atgcctgttc attattttca atagtaactt 118680 tcatgatcgg gaattcagat ggttcagtta ctggtgcagg gtcttcctgc tcttcagcag 118740 cctgatatgg attttccact tcattaaaga actcggcttc gttgctagaa agccagataa 118800 agttttcgtc aatgactgta cctcgtgatg aatatccaac tatgccagta gatgtcacaa 118860 ttttagtagg acgcccgtaa tagtcaacat ctaaaatttt aaaaggttcc atacctaaac 118920 gccgcgcata gattccgtta tcagtatggt ctttaataaa attttcttgg gcttgtttat 118980 ttttaaattg ataccattta ttaacttcaa atttaatagc cattaataaa tttccttcca 119040 gtaagttgtg ccgtcttcag taatttcacg aaatacacca taaattggtt gtttatcacc 119100 gactttctca tacacataaa cagaagtcaa gtgagtaaac ttgctagtat gttccttttg 119160 aactactacc aaatttggat caaataatac atcttcaaat tcatcattag tgcaattctg 119220 aacaatttta cgtttcatta caatttcctc attaattaaa cattggagcg atgcgtttca 119280 gaagagtatc agcacctttg gcgaatttcc attttattct ccaagttgtt ttctgtatca 119340 gtagttgata ttgatatagt accacaatca actactgatg tatatagttt tatgaaaaaa 119400 ttttaaactt tatgcacagc gagctttgct atagtgttta atccaacttt caggaatgac 119460 tttgtatgtt cctaaaaata ccgcgttgta cagcttaaca ccatcttcta cccactgatc 119520 ggtaatgtat gcacacatag cgcgagtacg gcgtttttga acaacccctt cctcatcttc 119580 agtaaattcg aattcataag gagcaacgaa cttaatagcc tgaccgagtt tccacttaaa 119640 gtctacacct acatgcgaag tatcaatcgt ttcaattcct ttagcaggaa cagctttcaa 119700 aaacgcagat tcaagaaatt tcgcgcgaac ataaccaaac tgaggtttag actttccatc 119760 tttaggaatg atacgcactt ttacttcaga atcttcatct ttaacgccgc gtttaagctg 119820 aatgcttaca atttcgacca attttcctgc tgctttagag cgggatttat cagatacacg 119880 agcaatttca ccaatattaa taatcatagt tatctctcac ttgttaaaaa gattttatac 119940 tccacaggac cattatactc tggtcccaag agtttgtaaa ctattaattc aaaatagcta 120000 ccaccgcact acgaggtact acactaaaat ctcctgcatg gacaacgttc agaagctcaa 120060 caccatcttc aatccactgg tctgttaccc aaccacagat aggattatca aaaggacgac 120120 ggatagacac agcagcacac aacaggtctg tagggtcttg ttcttcaact tcttggaaca 120180 ggatgaactc atcttcataa accaggtttt tctttatttt gttattatct aaccggcgac 120240 cgtggatgac gtaagatttg tcaaaccact cacttttggc aaattcttca acaataaatt 120300 cgccttcgcc aaaaacatca gtcagagttt tatgaccaga aatcaaggca ttagttttaa 120360 ttttaggttc aaccagtttg taggttttgc cgatttcaat agcggtagtc atagtaggtt 120420 ccttaatttc cagtggttta acagggcata cataagtgct tacaacatca aaatcaatca 120480 gtttagctac cggattcggt gtgtattcag gattataatt aaatttcata attatctcat 120540 ttcaataaaa tctacgagtt cagcatggga tttgcggaac attacttggt gtccaccaat 120600 gacaacttga tcatctggca cttcgtatac agcgagataa aatcctttag aagataattc 120660 ttcccgctct tctcgcgtga accatctcat catatcatat tcactagcga aagcaaaatg 120720 ataaagagct ataaaccatc ctggaatatg atattctact ccaacataat ctttcttgaa 120780 cttagtatta attgctatat tagcgttttt aactaataat ttgtcttcgt gtggtaaagg 120840 aattctttta ttattatcgc tatgatgcat aaaattaggt ctgtcataac ctacgtgtaa 120900 tagccactct tcgctccata aatctattat actcctgtac ggcgttattt gaacacaaag 120960 atttcgacgt attgttatag catcttcatt attaagaata ctaaacgatg attcaacacg 121020 ataaattttc attttattat cctcagtagc tatggtgtta taataccaca actaaccgag 121080 gaagtaaaca actttttatc gttttgttgg aagagataga ggatcgcaat cttcctctga 121140 cggagcatct tcaagaccca tagcgtatcg caaagcatac ttcatcatca ggatgtcttt 121200 cgcacagtca tgaatagaat tatgcgcaac aaatccatct aaagttccct ttggaagggg 121260 gcatgttgtc atatcacgaa caagcagaag tgcttcaatt ctggtacgaa tatcacgctg 121320 attccagaat ttacatggtt ctaacttaaa tgtgtcaagc tcattctcag atacaccatt 121380 aaggcgttga atatcacgaa tgagatcgac taaaattgga aaatcaaacg acattccacg 121440 gcaccagcct tgagatttcc aaggatcgat gttatgtgca ttgatgtaat cattaaattt 121500 tgcaatacca tcaatggtgc ttacatcttc atctgatggt gcaatgtttt ttcgagcttc 121560 aggagattga tttttccacc attcgatagt gcttttagta aaaagacgat gtcctttttg 121620 gctttttaaa tcaaatttga ttttaatgcc acgtgaaact aattcatcaa atgtttcaac 121680 tacttctgga ttagggtcaa aggcaataac agccaaatca ataacagctg ccttttcacc 121740 acttcccatt gtttcaaaat ctataataaa atcaaacatt aaattttcct tgctaaatcg 121800 cgaatttgg ctacagtata gtcttgaata taaactttat taatgggctc atcaataaat 121860 tttgccacag attcaatgtc tttttgtatc tcttcaagac tgtatactat ctttgaagct 121920 ttttcgcgaa tagtaatatt ttcaggacct ggattttctt caatgacatc tttaacattt 121980 gttaagag atttaaactg ccaccaactt aattcaatca ttaataatcg cctcataaag 122040 atagctaatt tcgcctaaaa cataatcatt aattgtaaca gttttcactt caccgcaaaa 122100 gaattctaac gcaatcaaat ctcgttcaat ttcttctaat tgaagcatca acttactaga 122160 ttcaattttt acagttttac gatttttacc atgagcaatt tcataaattt cgctaacttt 122220 atcttgaaga agataaaact gatctttagt tatttccacg aatagcttcc tcaaatttaa 122280 tcatacataa aatacatcat aacgaccacg ggtaacacca acataaagaa gttgttgggc 122340 caattcagca tctgcataat gaatgcaagg cgtataaatg aaagcacggt ctacagacat 122400 accctgagct ttatggaatg ttgatgcagg aagtgctttc actttactaa actgtgattt 122460 agcatcccaa aaatcactcc acggagcttt tccaccttta ttccaatttt tgtaagtttc 122520 tgcagtttta cctaaaaata agttaaactt atacagctct tcatcagatg aaattatttt 122580 aatcttttca cgataatatt catcatcgcc gtaagtttct actgttaaat cccaatgacg 122640 aattagatat tctccagaaa caccacgagc tttaacaaat gttgatgtat actctgcttc 122700 tataatacga actaattgtc cgttattaaa aataatttct gacacaggct ttccatcaat 122760 tttatatgtt ttaattaatg gttcctgcat tacaataatt tcaccgacaa taaaatcttt 122820 atcagtttca aaaatctttt tacgaataat gctatttaac ttatcaacag atttattcgt 122880 aaatgccatt acacgatttt caaacaaatc atctagagat ttgacgattg aaaaataatt 122940 taccataaaa tcgcgtaaag cggtatcacc tgtaaatcca cgtactccat gcccgtcaac 123000 aactttatca taaatccact taccgttgcg aacgtcagta gctacatcaa taataggagc 123060 attactgcgt ttaacttcag tgagttcaca ctgataaaaa tctttgtgtg taaagaatgg 123120 actgatataa gcagtgtttt ctcctgggtc aacaggtcta atttgcttat tatcccctat 123180 tccaattata gtacaccaag gtggaatagt tgaaagcaga attttaaata gctttctatc 123240 atacattgac acttcatcgc agattaatac cctgcattta gctaaatctg gtacttcctt 123300 ctgctcaaag aggacatttt cttcatatgt tactgggtta attttaagaa tactatgaat 123360 agtactcgct tctttccctg atagttttga aagaatcttt ttagctgcat gtgtaggagc 123420 tgctaaaata ataccagttt cacccgtaga tattaaggct tcaatgatga acttagtaag 123480 agtagtctta ccagtaccag caggtccatt aatagttaca tgatgtttct tttctttgat 123540 agccctcata acaatgttaa aggcattttt ctggccttcg gtcaaatcat caaatgtcat 123600 cgtaaattcc ctgcaattgg tatactaaca atacgcccag tatctaaaat tcgccgatat 123660 aatctttgtg tgtctacatc aggcttaaca cgtttaactt ctattttatt aaaccaaaac 123720 ttgcgtggag tctcaactag tcttggaatt cccataccta aagctagtcg atactgctct 123780 ttaagagtgg taaatacttt atcagcaata ttccattcaa aaaatacagc aggacgatgt 123840 tcatcaagcg gaactggcgc cgtaaatcca tctttatctc tataaactat cgcatataca 123900 taaaccatat tatcctcgga taagtttaaa aattgaacaa ttcagcggat atcctctttt 123960 cagtttaagt ttatcaataa aagacaagtt ttgataccgc tctacacctt gaataatttt 124020 atcacacata tcatattgca tttctgcttc tgacaacttt ttcacagttt tccaatcaga 124080 gcctttaaga agaacgttca atttaacagc ttcagcgcct tctgctatac gagaaccatc 124140 aatacgagct ttaagtgcta caatcgttag cttaatatca gaggtttgtt ttgatttaga 124200 aagctgagaa atgtgttcaa ttcggttttc acgttttttc tgtatagctt taatttgatt 124260 ataagtcttt ttgattttag cccatttctt ttcatctaaa tttagtttat gaactttttt 124320 cgcagatgaa cgaccaattc gcaaagcaaa taaatcacgc ttttcgatca actcttctaa 124380 agtataatca gaacgaaatg tattatactt tttctttact gcaataacat tccctttaat 124440 gtatccaacg ttattatcaa aacgttctaa tgataatttc tctccttcaa tacgattatc 124500 aaaaggttct cccgagtaag cacaaacttt ctgatctaaa atgttcttaa tgtaattgaa 124560 gtctaagtta aaatctttag aacgtctttt agcagatgcc tgagtgtgct ctagacgacg 124620 tgtaatttta cgaatttgat ttttagacag tttcatattt ttctcacgga cgggttaact 124680 acttatacta taacattttt acttcagttt gtaaacaact ttatgtaaaa atgctttaaa 124740 aatttcatgg tataatgaat ctaagtcctt ccattataga ttaaatcctt caaaatcaag 124800 agtatagata gtgtatgttg aatacttttt gtactcatat ctatctgcaa ttctaaatac 124860 acttccagct ggtatcatta cttcttgttc atctgaaact aattccatat tacgataacg 124920 atggctatct ggaaacttaa aactcggact atattcttta caacgtaaag cttttatagc 124980 atactcctgg aaattaaaca ccataggagc tttgaattca aaaataactt gtgtgttata 125040 ctctaaaccg gaagcaaaat gtagagctat atttttatca tatgaagctg atactacttt 125100 atcaaatgta ataatatcaa ttccttgatt taacacctgc ttagtctcag ctggaacacc 125160 tctccaaaga ggtttatcgt ttagaaccaa acgagatttg attatttcat ttaaccaaga 125220 atgatcgtct ggcttattag taatacaatg aattaaaagt tcaatttcag ataaattaaa 125280 tccttcagaa agtaattctt cacgaataga agcacgcacc gatgcatcca ttgattttat 125340 tttaaaatct tttagttgca ttactgagta tttcattcaa ctacctcaat atcataaact 125400 ttaaatgttc caaatgaatc gtgtaatttt tcttttgaaa tagaagttat tctatacttt 125460 ccaattggaa tcatccattc ttgttcacgc acaatcatca ttaagttatc agtacgctct 125520 gaatctaatc catcagtatc ttcatacgtg tacttaaact cagtattagg agaagaaagt 125580 ataatatcgc tgatatggtc agaataatta aaagctttat cagtttttaa gcgaaatatt 125640 atttcagtga aatactcaac ataagaaaaa ccacatgctg tgagtaaact agtagtaaat 125700 gaatctaccc tgttcgttga aaacacttct ccaacttgta aatctttaat aagttcttct 125760 gttgattttg atataccacg atataactga tatggtgatt tagttaaatg ctttttaatg 125820 attttattca attgccgatg aagagcttca ttctttttag cttccataca ttgccaaaga 125880 acagactgct caaagtcagt aaatttttca cagacttttt tatacatatc atattgaaaa 125940 tcaacgcttt cagcttttat agataactgt tcaacatctg caagattaat aatcatgata 126000 gcctccgtat acttcagaag ctatcatatc atcgttagaa aggaaagtaa acaacttttt 126060 gaattatttt gcccagggag cccaaggcgg agggtcaaga tggtatgaag ctagttcttc 126120 tagaagagca tctggggctt caattccata attctgtaat actatacggt actctttctt 126180 ataatcacta gaatcattct ggttattcgt agaatgatta tcttctaaca tctcaaataa 126240 atccatatta attcctagcg ataaaaacca aaatgacgat tagcttcagc aatctttctt 126300 tcttcttcgg acattctcca gcgtagtcca acatcaaaat gagcccagac catcctaaca 126360 aatgcattta tatctttaat atcttcaata atgaatgttt tacttttaaa aggctgactc 126420 gctaatttaa ctttatcatc ttcaaacagg tcaaaaagga ccatattcat gagctctttt 126480 atagccttta atagttaaag cttcagaaga agaaaacggt gaatcagtat tctgcaaaat 126540 atcttcagta tgctttataa ttagaataat attttctgga tattttcttt cttttatatc 126600 tttaattaaa atatccggat tttctgctaa aggaataatc aatgagcaat ttttatcaag 126660 cgtatttact gatttacctt ctttagacat aaattctatt gaatagtgtt ttgctacttc 126720 aatcatgtga tttccttttg cctactaatg gaccatcggg aattttgttt tcctggatat 126780 atttctcatt ttcttccatc attttactgc caattttaag aagcaaatcc agtgcttcat 126840 ttgctttagc cttggcctct tctaacgtca tatctctgtt cacgatttat ccccatagat 126900 gtctctcatc aatttaagcg ctgagcgttc taatttcttt tctttctcag cactaatcat 126960 tgatttcatc cattcttctg attcattctg catttcttta tttgcctgtt caacccaacc 127020 atcatcaatg tacattgagt ttggtctatt gaaccattca aacattttct tcagaacttt 127080 catttacttt acccaaaaca acagtaggag catcatcaaa ttcatgaatt tttagcaaat 127140 ttggatgtaa actattccat atagaagaaa taaagtatga taaagcatct tcactcgcaa 127200 ttataaattt atttccttta tctattttcc aactatataa tgaatcatac gaatagaaag 127260 ataaaggttt atcattatat tgttctgcgc taacattaat gtattcggat ttagtaaatg 127320 cttcaattgc tctaaatgga atatttggta cagtttcaat aataccaatc tttttaagct 127380 ttatttcagc atcttctgga actggcattg aaacgaaatt ttctacgaga tacattgggt 127440 cacaataacc cttatcaatc attactgcta cggtaattgg aacgtcttta gcaaacgaca 127500 tgctatcact gctaatatac atttcaaaca aaatcgcttc cataattttc ctcaatcaca 127560 ggatgtagat gaacaactag aatcacaaga acttccacat gaatcgcccg tccatacatg 127620 aacaggaaca ttagtatcat atgaatcaga attagactgt gtattctgtg tattagatga 127680 tgtagtaggt gttgaccagc gccaaggatt tttataatat tcttgagctt cttcataagt 127740 catagtaact gcttctactg ttccatctcc catataaaca tattcaacta cagttaaagg 127800 aaggtagtcg tttgaaatag gaactacacc ttctccagga gctgtagaga aaaaatccgt 127860 aaagaaattt ttaaaccaat taaagataaa cattacaaaa agcctctctt gaattcaact 127920 tgcttctcgc cataatcata tcgaatctct gcattaaatt cgacagaacc atctgcgtac 127980 atcataaatg aatgcacaac aacttctgta gaccatggct gtagttcgta tttcttcatt 128040 acatgccgtg aaatgataat atctaaatct tcatttggtt taatccaacg atttaacata 128100 gtgctctcct ctataagata attttattat accatactca ttttggaaag taaaccggta 128160 aaatgaaaaa aggactcccg aaggagtcct tgaatttatt caccagttac tttccacaaa 128220 tcttcgtttg cagtaatcca ttcagtacgt tgattttctt catatacagt agtatatgct 128280 gctttttctg aagggaatat ctgataatga gcgccagaaa ttttgtgaac gtcagaataa 128340 agagggaaag ctacagaaat ttcctttcct tcaattttct tatttccatc taatttctgc 128400 tcaaatgttt tgatattaac ataaccgcga gtactagcca tgtaattctc cttttattta 128460 aattacatga ttatttataa taattctcgc ggcttttaag tcgtcgttta aataaacgag 128520 ctattaataa cctcggtctt gacgcgcgaa gttttcagca tttttcagat aataaagttt 128580 aaagatttct tcagccgtaa gaccaagacc ttggaacatg ttcagaacga aatgaagaat 128640 atcaatcatt tcgaatttaa tttccaactg gtcttgtgga gacaaatcag taattagagt 128700 ttcacgacgt tcaccatgct gcgacttcca aggcttccat acagcagatg catctttttc 128760 gccattgctc ataccgccaa gagaagtcag aagttcacgg aattcatcgt caatataatc 128820 tttctgatta cgcagccaat caacaacttc accagcagta gccaaatcat caggatgacg 128880 gttatattca ggtttatctt tagctaaacg aatctgcaga gatttctgca tgtcaagcat 128940 tacctgcagc gggtcttttt catcaccaag aatatcccag tattcatttt gagctttatc 129000 agcgccttcg atcagttgac tacattcgtt aaagtaagcc attatttttc ctttcaattc 129060 attaataagt taaataatta tatcatttga atatgtaagc aattaattaa aaatatatac 129120 ttcatcagtt ccattctttt ctttggaatg atatatgtta aagacgtatt ttttattaag 129180 atgcttaaca ttatattttt tagaccattc tttaagaaga gtgttttcct ttccgtgatg 129240 ctctaaaaca ttcgacagtc caaattttat tcctctgtca tttaaagagt ctaaaagatt 129300 taaaaggtct ttttcttcat cttctgacca aaatttatta taatcagcaa ctgttataag 129360 atatggaggg tccacatata caaaatcgcc gtctagaatt ttgacatctt taaaatgcaa 129420 tgaactaaag attattttat cacaattttg tttaaagtga ttaaagcgtt tttcactatt 129480 tttgtttata gttctttttc caaacggagt agtaaaattt cctttatcgt ttatacgaat 129540 catattacta aatccgtgaa aatgaagaac ataaagtaaa agaggatctc tagttttatt 129600 ataatcttca cgtaatttca aaaactcttc ttttgatgtt tttgatagtt tatagtgctt 129660 tattactttt aaaacgtcat cccatgatac attaataaga cgcttataca tttcaataat 129720 tggttcttga atatcattgg ccaatacagg accattgacg ttcaaagaca ctgataaacc 129780 tccacaaaat aaatccacga atctgtcata ttttggaaag tgagacttaa gttcaggtaa 129840 taatgattgt ttattacctg tatacgcaat agctcctagc attatattct ctcatttatt 129900 gcagcaaaaa acgaattata taattcttca tcatatgtat ttgatagtaa tactaacacg 129960 ttttgtgatt tagcatattc attaaacctt gcttggatgg ttggattatc agtaaatgat 130020 tctctttttg tccatttatt acgtggataa tatccgcatg gcaaaaaatc taatatcatc 130080 aatgacacag ggttttcagt ttttgtgtat ttttttaatt tctctttatc ttctaaatat 130140 attccaaccg aatcaatagc tgtacctcca ccaacttggt gtttaatttc aattatatgc 130200 tttttaccat tgcgagaaat gacaatatca aatcttctag tacgcttctt agttgtaaaa 130260 ttcgaacaaa acaaattatt tgatttttca gtatcgtcgg ttaaaaccat tttttcttga 130320 taactaactg aacaatcagt gaaattattct tttactttat taagtatgaa attttcaact 130380 acggcagata ttttatatga atctccattt aaagccattt catgcacaat tttattaatc 130440 atcatatcat cctcagcaat ttattttata atatcataac aagctgagaa agtaaacaaa 130500 tttatgataa atattaattt aaaggaggac atatggtaca aaaattaatg gcacttgtta 130560 atgccatcaa aggtaataaa aggcgcatag cttttactat ttctgctatg ataggaattt 130620 tactttggaa ttttgtttta tcgccagttg ctattgctca tggcgttagt attccagtag 130680 ttactcttga tacattcgta gatttagcat ttgctttagt tgggttaatt taaatcttag 130740 catatttaga tagccgcatt ttagccatca acccctgtgc aatattattt ttcatatatt 130800 ccataatttg ttcaggggtt gcaccttcct ttctaatcat atcattaaca tcttttgatt 130860 tccagggaga tttatcccaa aacataaccc tttctcctgc atcaactaat ttagtcattc 130920 gtttaatagt gtcaggatga cgaggttcat tatctaaaac ccacactcgt ctatctttaa 130980 atggaacaac ttctaggtct aattgaccac ccgtaatagc tataccattt tcaataaaaa 131040 gtgaatctat aggtccttct agaacatata catcaccatc tttaactcgt tcgactccat 131100 agatttttgt tgcctcagga taagctttga tggtgatata tttttgagga gcatctttct 131160 ttaatgcacg tccttgaaac gactcagctt ttccattagc attataaatt ggaataacaa 131220 gggaggctc aggtatttcc tttttatatg ttcccggtgc tatgctatta accaatttag 131280 gccattcggt tgtaaaccaa agatatttcc atttatcctt tggaatacaa cgagctttta 131340 catattttat aattgaatgg tcttccgcca gtttatctaa tctaacacat gacggaagag 131400 atttaattat tttcttctca ggttgtttag gaagttcttt aggtttttct actggacgac 131460 ttttaccttt ttcttttctt atttcaaaga tatactcacg atataaatca ggttcaaact 131520 cctttaaata tattccgatt ggtgcatgat agttacagtt ataacaatga atatttcctt 131580 cattattatc accataatac catccacggg ctttattttg gtcggttttt gaatctccac 131640 acactgggca tctaaaccgc aatttaaaag ttgaactatt atttacttgt gtgaatttag 131700 gtaaatgagc taatgcacgg tatgcaaact cattatcaat ccaaggtatt gatgacattt 131760 ttactcttct ttttctttag attcctcttt tttcttttta ggaatctgtt caggaccttt 131820 atttactaca gcgcccgacg ttgttccagt agagatattt tcaggattac cacctgaatc 131880 tccagcgacc atatcttctt tgataaattc tttaaatgtt ttcatattaa cctctattca 131940 taaaagcatt aaaaatttgg tcatcaatag atggaatagc aaccttttcg gcatcattta 132000 gcaaatcatt aatttcatca gatagcataa cacatgtacc tttatttcct gtaattgtta 132060 ctgcacaatt acgaacgttt tctttatcaa attttaggtt aatattttcg tagtgaaaat 132120 cctttaatgc cgaatatatc tttaaaatga aattgtcttt tactacaata aacccaacct 132180 cactattaaa acgtggttca tggaaactgt aataaacctt ttcatctata aaatcgtatg 132240 aaattttttc catttttaaa tatgaaaatt cagaactata catattaacc tttattcata 132300 aaagcattaa aaatttgatc gtcaatagaa acttttactt taggctgttc ttcaaacgtt 132360 aattcatatc cacatattac aattttgtga tcgataccaa aatacacaga agcaatatta 132420 ttaatattat tttcagtgaa atctaaatca acatcaatat ctttttgact aacgctcaaa 132480 ggataattaa tacgaataat tcgattatct ttaacaaaga ttccaccgac atactctgtg 132540 ctgcgtttaa agtttacacg tttcctaaat gaaaaatatt caggttcttt atgggctcga 132600 ctcatagggc ttaaagtgta ttccgaatat gaaatatcaa atcctacacc ttcaatatga 132660 gccaaagtgt catgattaaa ccaattataa tcgtatgcca aatccattaa attgtaatat 132720 gtgaaaggca ccggattaac atcatatgtt gtacctttaa aatctgccca ggcaacgatt 132780 tcgttatctt taacaattac aaaaattgtg ccaataagat atccacggtt attttcatca 132840 ggcgttatat tataacattg tgcatcagga aatttaccgt atttaaacgg tggatttttg 132900 tgcatataat aaatcatatt attcgcctgt gatttcggtt acgatatttt tattattaaa 132960 gtttttatcg caatacagaa cataattata ctgcattaca ccaccagact taagctgttt 133020 ttgcacttca gctttcattt caggacgatc acgcttaacg atattcataa tatctgcttc 133080 aatttgagtt tcaacctcag tctgatccgc agtcatagac cattcacaca aatctttatc 133140 ataacctgcc atagcaggct gagcagcaca agaagctaaa gcaaaaattg cagcaaaaac 133200 aaattttttc atgattaatc tcctcagtag tttatgttta tatagtatct caatttccaa 133260 taaaagtaaa cagttatttt aaaacttttg cgtaatcaca tgttacaaac tgtttctcta 133320 gcttaacgat cttacgaaaa taccttttac actgacgaat ctgtcgcttc gtaggacgta 133380 cagcaaactt aataaattcc actcgaccaa atggaggact ttcttctgct ggaatatcta 133440 acaccaattc ccacgtatcg gcaataagtg ctttgaattg cgtatttttc ctgacgttat 133500 acggagtagg tttaaataaa acaatatgca tattatcctc ggcaatccac ttcacatact 133560 ttcttgtcat caatgaaagc tttaactaat gctttattaa cttcagcata ttgagtagta 133620 gcccattgaa cgtcatcttt catcattgtg gtttctttag taaacatgct ttcattctta 133680 aaccacccca taaaaactac ctttaccaat tccataacaa tctcctcatt taaccaacaa 133740 gactactata ccatagtctc gtcagcttgt aaactaaaat tttaattcat ttgccaaagc 133800 atctaactgt gctcgagtgg attcatttct ttgatagcga ttctgttcag cctgaatctg 133860 ttgtgaacct gctacttcac tcacttcagt tggagtagaa tcttgttcaa tttctaccca 133920 tttctgattt cctttttgaa cacccatcaa aaacttattc catttattct tatcaccata 133980 tcgtgatttg atttgcttaa tgagttgttg ttcagcagct gccaactcct cggtttcaat 134040 gaccgcaagc ataaaatcag ctgttgctgg aagaccagca gattctgcaa tatcgctcat 134100 gttaacatcg gaagagtccc aagcttgttt accaacctgt gctgcagtcc aaagaacagt 134160 ttcggtttca acagccagag cacgcaattc ctctgcaata gctttaacag ttgtgtaact 134220 attttctgaa taaactctaa tgcggcaaga tttacaaata cctagatagt cgacaataat 134280 gattgttgga acaaaattct tcttgagctt taattcattt aaaagtgatc gaaatgtatt 134340 agcgtctgct ccaccagtag gatattgttt aacgattaaa cggccgaggg tagatttctc 134400 acgccatttt tccatttttc ctttatattc agcgtaagaa atatgcccat catcaatgtc 134460 atcaagagaa acatcaagca tattagcatc aatacgctta gcacagactt cttctgccat 134520 ttccatggaa atgtaaagaa cattatgtcc gagctgcaaa taatctgctg ccaatgaaca 134580 caatcctaat gacttaccaa cgttaacgcc agccattaaa acgttcagtg ttccagtctc 134640 agctccgcct ttagtaattt tgtttagaat tctgagttta aatggaacct tacgagcttt 134700 attcatataa gatagccaac gtgcttcgta gtcatccatc caatcatgac caacgtaact 134760 atcaaatgaa attgataatg cttggcgcat gatgtcagga atagcaccta catctggcat 134820 tttcttattt cgtttttccg gaggaagctc agcattagtt tgaatttcaa ttattttaga 134880 cgtagcatta aacatcgccc tttgctgaac atatttttct gtttctttta ctaaccagct 134940 atggtcttct ggagaatcgg ctagtttcga aataagtgtt tttacaccag aatattctgt 135000 ttcagtaaat gaactatttt ctaatgcaac atttaacgca ttaatagatg gaacgctatg 135060 gtactcatta acatgagatt taattaattt gaatgtattt ttagctggac cactttcaaa 135120 atattctgaa tccatatatg gccaaacttt tgaaaaataa gcttgatcaa atatgagatg 135180 ggaaagaata atttctacca cacttactcc ttaaaagaat ttaaactttt tctttgacct 135240 tttattgaat gcatcttgta gttgcattgt aatacatttt tctacatgag gagctaactc 135300 agcttttctt tcttggtcaa gaacagcaaa gtccattaca acctttccat caacccaatc 135360 taattttgtc acatacacaa tgtgtgtaga accatcttct agtttaatga caatctcctg 135420 gataacattt tccatggcag atttaattat cttaagagac tcattaaaaa gacgttcttt 135480 tctttcttct tccccctccg aagaggggga ttcatcgata atttctagat ctaagtctaa 135540 atcatcttta ttcattaaat tcttccatat cacttaactg ctcgaggtca gtttctaaat 135600 cagctgctga tttactttta ctttctggag atttaaattt ttcaaccttt gagttaatca 135660 attcatcaac ttcagcttca acaatttcat tactatcaat agcacctaac tgataagcac 135720 gtttaatagc atctcggaat ggttgatgct taaataaagg accccagaat gtagtgcagt 135780 tggtatcttt tgcacgccaa gatttttctt cgcgaatcat ctcgccggtt tcttcatcaa 135840 gaaattcacg agcataccag ccattttttg gttttactac aaatcctaat tctagagcca 135900 tatctaacaa tccagaataa ggatcgatac caccgtcaaa tttaacatca ataaagaatt 135960 tacttttttc tttaacggta cgagattttt ctacatttag aacaaattga tacccctgaa 136020 gatcagaacc atctttaatc tgacgcttac cgataatgaa tacagtatca gccgaataca 136080 tcggtccagt accacctccc ataactgttt tactaaacat ttcttgtgtt tcgtatgtat 136140 ggttaatagc aatacatgga atatttttag tactaaaata gggagttacg atacgaaata 136200 agcttttcat tgttttagct ctagtcatat cactaacaac tttttcattt aaagcatctt 136260 cagtttcttt cttagaagct aagttaccaa gtgaatcgat aaaaacgact accttttcgc 136320 cacgttcaat tgcatccaat tgattaacca tgtcaatacg taattgctca agtgattgaa 136380 ccggagtatg aattactcgt tctggatcga ctcccataga ccgcaaataa gcaggagtaa 136440 taccaaattc actatcataa aacaaacata ctgcatcagg atattgacgc atgtaagatg 136500 acaccattgt taatccaaag tttgatttaa atgattttga tggacctgcc aaaattaaca 136560 gaccagattg cataccacca gtaatttcac cagaaagtgc aatattcatc ataggaattt 136620 ttgttcgaac tacatctttt tcattaaaga atttagatgc tgttaattct gcagtcaatt 136680 tagaagtaga agctttaatc aaacgggatt ttaaatctgc aatagacatt cattttttcc 136740 ataggcatca ttatattttc ctcactggtt aaagataaag taattataac acaataaatt 136800 taggcattaa tcaactgcta ttggatgaat agcattaaac ttatgaaatg cttctgattt 136860 ttctttacgc gaaacacaca tgcgaagaac ctttaatggc tcgtcttctt cacccaacga 136920 ttttcgtttt tcaatatttg aagttttcca acgagcttgc tctggaaact ctctattgat 136980 ttgctcaagc gctctattat gtttagaatt actacgaatt gaactacacc caccgggagc 137040 gtgtgatttt ccagatacaa ctagatattt gaacaaggcc aaatgcggat aaccttgatt 137100 aattaaattg agaaatgcat acatatcttc gcataaatca atttttccat acccaatttg 137160 ttctgccgta agttttccga ggtcatacca tgtattcgtg aatccatatg agttttcacg 137220 ataattaccc caagatgaag taattttaaa aattggtaga cgagcatgac cgtgataata 137280 cccgcaatcc atggcatctt caacgtattg aattaattca tagaactgtt cacgagttaa 137340 ttgattaatt ttatctacac gccgtttatc gtctctcttt cgtattgaac tcatacgaat 137400 agtagtatca tcatcaatca tccagattcg ttgacctgca tacatatcag taattgcttt 137460 acgagtaccg gcaattccat taacatcatc aggaatagtt acaattttag ctctagaccc 137520 ataagcatca taataagctt tttcttcgtg ttcacgcact acaatatggg gttcataatc 137580 agtcggaaac atattaaggg cagaaactgc ccctacacgc tgataacttg gaattacgaa 137640 ttgaatcatt tccactcacc gttataatct tttttcacaa tatgagtttc gccagtattc 137700 caccaatgat caaccaagta aaaatgacga gaatatacat gaagacttcc aacattccat 137760 ataatagaac ctgctttata ctgacgagtt gaatcgcctg cattcaaatc agatactaat 137820 ttatctaata cgtatttttg ccatgcataa tcattacgga atccgaagac cacgtcattt 137880 gagcgcatgt taacaaccgc attgactttc ttatcacgaa tcaggtactg tactgtatta 137940 gtacacatga aatctgacat accatcttta ttgtagtcaa actgcataga tggacgagta 138000 taaatcatga taccacgtcg agaatcagga ttttgaccaa gttcagctaa acacatatca 138060 tactgggcat agttatcttc tgaccagata gcccaaccat aattcgagtt aatttcacct 138120 ttagaagatg ctacttgttg ccaaatcttc ggtgtttcac ctggaatatc tttaacaaac 138180 agactttgag acttatacca ttcaagttca cgctgaatgt attcatcatt aagagcgcca 138240 aaaataaacg gttcatctgc tacaaatgat gcgccaataa tttcaatagt tttaacaccg 138300 gttttatcaa ctacgaaatc tttttctttt aatgcaagcc ccaaatgaag acggatttct 138360 tcaactgtca tagagtcact aatcatttaa acctcaattg atacattcat atttaacttg 138420 taacagtaat aaactccaac ctaaaataat agttggaatc ataagaggaa ccgttacact 138480 atagtatata cttattataa ccatcaagat taaaagcaat gctgttataa ttttgctttt 138540 cattccttct ctctgatgat aattacctga tttggctgcg cagacttttt agtttcacct 138600 gcaattgacc aaataaatgt aataaaccaa ccaataattg accagttaaa cagtaaagat 138660 gtgaaaaaga ttcctactgt cgattttgac ccacgcatca aggcgataaa ccatggaagc 138720 atgtatataa taatagccaa cacgcctgaa actaaaacca taaaaattga acctgctact 138780 aaagtttcca tgttttcctc acttagtcaa attttttaca catgaattat aagaattcac 138840 tacatactcc atcggagcat ttttacctgt acgccattgg taattattag cccaattagc 138900 ccaaagttcg gcacagtagt tttcaatttt ttcttcgtgt gtaattacat ctgaattacg 138960 atacgcttga gcagattcat ctggacgaat agcttcgtca aaattcgcct gcatttgttc 139020 tactgtctgt tttggagctt ctttatagca cttgacatta ggattataaa atttgcttga 139080 accttttaca atttttccta catcagactg atttactacc ggtccttgag ctacacaacc 139140 agtaagacct aatgcaataa ccaaaatagc gattttcata ataatttcct caaatacaag 139200 tagtaattac tccagtagtg cttacacaga tattacctaa ttgaacaccc agcgttccat 139260 tagtattcat atgaagatta tcatcaattt ttgttgatac tttaccattc atgtgaataa 139320 cagtattaga ttcaatcaca ttctgagtat cattttcaat atcaataaat ggaacagctg 139380 ctaatgcaac taaacacgct gctaatgcaa ctaaacacac tgctaaacaa ccataaacaa 139440 ttttcatttt attctccaat ccatatcagt tgatagttgt atagtaccat agaagaacag 139500 ggatgtaaac agttttgtga aaaaaatttt tagggaatcc aaagggtcca gaatcatctc 139560 tttttcataa gtatagattt atattacttg tatgaaaaag ggacctggag gtccctagat 139620 ttattctatc agccaaacag gaagtctaac gaagcttttt cttcatagtc catgccagcc 139680 gattcacaca tacctgcaag cggtttaaca aacgattttt ggaacaaagt tgagtggtca 139740 atccaagata gcacatcaga acgaatttct tttggaagtt ctgtacccga tggccaagca 139800 atgcacttgt caccgaatgg atttccttca cgtaatggaa gaaccattac tttatttcca 139860 tccaaaattg gagctacacc cagaccacta acagctcgac gataagttag cacaccgcga 139920 atatggaacg ggcatttaaa tcctggccaa cctttatcat catatttcgc tatatcgttc 139980 gcagttttta cttcagcaat aactttatag tcaagttgac gatattcttt ctcgaagttc 140040 ttgtagtatt cttggacaga ctcttcacct tcctgaagaa tacgacgaat actttcttcg 140100 agagcttctt gcactgcttt tggtgttgaa ctctgctgag tttccatacc catgattttt 140160 agatgcggtt cagcaaatcg tttatcttcc atatcataaa cgttcagagc ataacgcttt 140220 ttcgctttcc aaaatccacc aacgcccttt gaaccaagtg gagggcaaga aatagcttca 140280 cggtccatat gcatcagatg ctcgcggtta ttcatataat cacataactc acgatatgca 140340 acatcaatca taggttccat ctttttctta ccgaactgat tcatgaattc aactaaatcg 140400 ttctgctctt tgaatcggtc aagaccaact ttttcaataa ctttatctac acaaacatat 140460 accgaatcag tatcacctgc tgcgataaaa tcttcaccat tagttccgca tactttattc 140520 agatattcat tgattttacg agcaatccac tgaataccga cttggccaaa aattgtgata 140580 gcagtagcat ttcgcaaatc atagtaacgg aaatgaatat taccaagagc accataaaga 140640 ctgttaatga gaattttacg gttcagctga tttgtgttag caagtgtagc agctttttca 140700 cattcctcaa tcagactatt gagaacagat tcagtataat tcgacagttc atttaagaaa 140760 tcatcactga acttaacata tcgttcaact tctggtttag ttgaacaaga ccctgcgcct 140820 ttcataataa tctttttaat agcttcggca ttcatttctt cagcgaacat tttctttttc 140880 cagtctttac gctggaaaaa tactttagcg atttcctttg gaatgatacc ttcttgatgc 140940 ttatcataca tccatccatt cggagaacaa gaatattcat cactcggttt aggagctgtt 141000 cctgcaatat attcatgaat tggatgaact ttaaactgcc cacgaatagt ctcaggacta 141060 atgttaacct gacgaataat gctaggatac agagacgtca agtcaaaact cataatatat 141120 cgacgagcaa ttggtttagg ttcaaacaca aatgcacccg gaaaactctg tttaacgtgc 141180 gaaccttgtt gaggaataac cttatgttca cctttcaatg agttaaaaat aatagcatcc 141240 caagttttaa taggactcat tacaccagaa aaaggcattt tagcataata agacatactt 141300 aaaactagat cgataaaccc gcgaatttta tcaattgctt gaactgattc tacgtcaatg 141360 atgttataac taatgtatcg ttgatgatta gtttcacgaa gtttattaat aggaccatcg 141420 tacggtaatt tacctttttt ggtttcatgt tgagcaactg attccaaaga gaatgacggc 141480 aaattagtaa atgcgaattt cttgtacaaa tctaaataat caagaataga tacgccatca 141540 atagaataaa tttctttgct accgtacaca ttttgaatta gtttagattt tacccgaccg 141600 attggagaga aacgtttcat actgcgttca ccgagaacca ttttaacgcg attcatgata 141660 tatggaacgt caaacccctc aatattccaa ccagtaaaaa tagcaggtcg tttctgttcc 141720 cagagattga tatattccat gagcatatca cgctcattat cgaatggcat ataaattact 141780 cggtcaagaa tttcttgagg aacttcatca ccaccttcac agtcaagctt agcagctaac 141840 tttgcatccc attttgatac tgaaccgtac attgaattca aaaggtcgaa aacataaaaa 141900 cgatcgtcaa ttgaatcata atgagtgata gcatcaattt catattcagc tttcattggg 141960 tcaggaaatt tatcaccagt aacctcaatg tcacagttag ctacacgaac aaattttcgg 142020 tcataaacaa tttctgaacc atacgtatca ctgatataag cgagtttaaa atcgttcata 142080 ccaagagctt cgagaccgat gtcttccatt cgcttcatcc aatctcgagc atctttcatt 142140 gatggaaatt tttgaggagc acagttttta ccatagatgt ctttgtattt tgactcttcc 142200 ttacaatgcc taaacatagt cggaagatat tctacttcac gagtatgttc ctttccgttt 142260 tcatcaatat aacgctcaac aatgttattt ccgactgttt caatagagat ataaaattct 142320 ttcatagata ttccttagtt tatagcccga gttattaggc tcttgatata ttatactcca 142380 attaaggggc cgaagcccct tgcttaatta ccaatcgtat atttaggaac gagtttccat 142440 tcatgttttt gtttaaaaga aataactcgg aagttattag ttaaatcttt cataaaagtt 142500 ctttgaccag ggacgatttc aatcagtccc caatcttcta atagccatgc aatcgaatca 142560 cgacgaactt catcttcttc tgtcatttca acttggcgac catccatacg aagcatttct 142620 ttaaaatgaa cgatatagta tagtcctttt ttctgaagaa tatgacagga ctgatacaga 142680 actttatctt tattattagc aattcccata cgagtcaaag tttcttttac tttcagaaaa 142740 tcttcaggtt ttttaagagt aatttcaatc attttaccat tccaatgcta gttttttgag 142800 ttgtttctgt tcttttacgt tcttagtcac ttctttcaaa aaatcatccg tgactaaacc 142860 ttttagttct tttaatacta aaggaagttt tccattttta gtaagaattg atttatagtt 142920 aattgcatca tttgtattaa cttgataccg tttagcaagt aacttaataa tcaatacttc 142980 agtggaatct tcaaccagtt ttgcccattt accatatctt ttaccacgag gaactgcagc 143040 catcagataa ttaaaatgag cttcatcact taaacctgat ccaattaaat tcatagcata 143100 tacagctggc atgcattcag gaaattgtga taatgcattc tcaaccatgt attttgaata 143160 atctttttga gcaatagagc atttagtttt attattaata gctccaatta tttcaaaaaa 143220 ttcattttca gctttttcct tgaaagaatc agcagcggat tggacagctg tccaatcttt 143280 tgaataccaa gcaacttgat gctcgtttaa ttgaatatca tcttcaaata agctcatatc 143340 acttccactg catttcacat gctaactgaa tgaaaagata tgctaaatgt aattcagtat 143400 tagccgcaat tccatgatac tggttatttt caccaacaat ttcatacata cgaataatac 143460 tttgcggagt tacgcgtgta tagatttctt cggcaagttt acctacgaac cacgaataat 143520 cagctgcata ttttggtgct aaagctctga gctgtttaac atctttattt ttgagagact 143580 caagaacatc atcaatagca ccacgatcgt tagtaaccag tgataaaata ccagcatcca 143640 aaacaccttt agatgaataa ctatcgagct cgccaatagt tttacgaaaa tcaggaaaat 143700 tctttttaac caaagctgct acaactttca tatcagctat agcaattcct tcacgcttgc 143760 agatttcagt caatcgacga atcatctgct tcatcatttc aattttatct tcatcggtcg 143820 gttgaccgaa tgtaataact cggcagcgtg actgaagtgg tttaataata ccatcaatat 143880 ttttagcagt aataataata ctacagtttg aactataagc ttccataaag gaacgaagat 143940 gtcgctgaga ctctgctaac cctgaacggt caaattcatc aataacgatt actttttgac 144000 gaccatcaaa tgaagctgca ctagcaaaat tggccaaagg accgcgaacg aaatcaattt 144060 tacaatctga tccattcaca aacatcatat cagcatttac atcatgacac aatgcttttg 144120 ctacagttgt tttacctgtt cctggagaag gagaatgaag aataatatgt ggaatcttac 144180 ctttacttgt aatagattta aaggtttctt tatcaaaggc gggaagaata cattcatcga 144240 tagtagatgg acgatatttc tgttcaagaa tgtgttcttt ttcatttact gtaatcataa 144300 tttcctcatt caagttttag tgtaaattat aaagggccga agccctttat taaaaatcgt 144360 gggtagaatc agcttcaaga gctaccacat aattcgcgtg ttcaccttca aatttagcag 144420 caccttgttt accttttgcc cagagcagaa gtttataatt tcctggttgc attttcatat 144480 ttgccatatt gataatgaaa ttaaatgtat tttcaccgtc ataatcacca agagtcaaag 144540 aatatttaac acgggtcaga gcagaatctt ctactttatt aaaaccgtta attacgattt 144600 taccttcttt taccgtgata gcaattgtat caatttgcag accacgagat acacgcaaca 144660 gttgttgaag gtcttcagct ttaatttcag taacaacaga tgctaccggg aatggaattg 144720 gtttattagg agcaactact gtactcggat cggctgctgg ccaaaaaatt gttgagcgag 144780 catcagcaat tttaatatta ccatcttctg actgggaaat ttctgcatca tcattaacta 144840 aagacagaat accgagaaaa ccgttcaaat cgtaaattgc tacatcaaaa tcaataacgt 144900 cagaaatatt tgcttccgca taagttgtac cattaactgc gcgagtcata ataaattgac 144960 cggatttaag cataataccg gagttaatag tagcgaaatt tttcaaaata ttcagtgtat 145020 ctttagacag tttcatgtaa tttccttcaa ttcaaatgag atttaatttt ataactaatt 145080 taataaagca attaacgatt aaaatcagcc gcaattgttt ccgcaataat ttgagcagca 145140 acaattagac gttcatctgc attaccgcaa taatcatctt caaggcgttc accacatgaa 145200 gtcataataa atttagcacc agcgtttaga gattctgtag tatgtttgcg cattagttca 145260 atccatttat tacttacttc acgatcgata gcttcataat acgcatgacg agcaggtgca 145320 gatttaattt tgttctgaat aacttccatt gcgttatcag aaagagacaa aacccatgct 145380 cgacgaattt tattttggtt ttgtggattt gattcagaac gcacgtgttt tggctgaata 145440 tcttttacat caacagtata attcacagta attttagtca taatacacct ttagtcataa 145500 taatcagtaa cagtccaagc ttcatttcta ttggacatta tttttgtata ttctgattta 145560 aatgcattcc taagcataga ttcagtaact atatgctctt cgttagaaaa attatttctc 145620 agaatatatc gttttatttc aggaatagtt aatagatgct gtccagttga atattccatg 145680 tttttcctcc atagagatta tactctaata aattaaagca taatctctta taaattaaac 145740 cattacagta aatcgaccga ctttcttcat ttgaagatgc tgaccatatt cttgcgggtc 145800 atggtcttta tgcgaaatta taaaaacatt agtgtttttc attgaattta taatattagc 145860 tacaccttta ataccttcgg catcaaatga cccatcaaac acttcatcaa gaattaatgt 145920 actaatacta acaccagata cgatagaagc aatatcacgc caagtaaata aaagagcaat 145980 atcgattcgt gccttttcac cttcactaaa tgaagcataa ctaaaatctt cacgaccacg 146040 ggatttaatt gtctcattaa attcttcatc taatgtaaac acataatccg cttccattat 146100 tttaagataa tggttaatct gcttattaaa taatggaatg tactttttaa taatagcacc 146160 tttaatacca gaatctttga gcatatcagt caaaattcct cggtggtatt tttccattac 146220 taaattagtt tttgtcttaa caattttatc aagttcttct tgaagcagtg ctatttcatc 146280 agcatggtca ataaactcag aagatgcttt ttctatagcc gctttaacct ttttagcttt 146340 atctactgct gcgatcagag attgcttttt attgcgaata tcatttgcca acgactgctg 146400 ggttttaata ttatctcggt attcatcaac aagaactttt aaattatcac ggtgtgttga 146460 aagctgttca aacgaatgcg tacattcaga aactttatct ttaattttag aaacaacttt 146520 atcaccggaa cttaattgtg acaaacaggt tggacataat ccaccttcgt gatacatatt 146580 aatgacttta ttatacgagt caatttttga tttaatcaaa actgcttctt gaccgatttt 146640 attaaatgca tcagtagggt cttcatccaa aacaatatta actaatcttt cattagcttc 146700 ttctatttcc gattttagcg ttctagcttc ttttgccaaa tcatcataca tattttgaag 146760 acgagtaaga ttgtcaccag acaatttttt ctggcgttca acattatcat tatatatttt 146820 aatttgttgg ataatactat cttttttaac atcaagcact tggttttgtg aatttaattc 146880 acgtattagt gctttattaa gcttatccat ttcagctaat gttcctacct cgagcaggtc 146940 ttccacaagc tttcttcgcg caggggtcga caaacccatg aaaggggtat accctgctgt 147000 accaaggaca acaatctgct tgaaactggc atatgacatt ccgataagct gttcaaattc 147060 tgcttggaaa tctttactgc tggcagattc attaagacgt gtaccgttaa cggtgatttc 147120 gaaaacgttt ggtttttgtc ctcttttgat ataatacttt ttctcatcat attccatcca 147180 cagttcaact aaaagttctt tcttatttgt gctgtttatt aattgacctt tctttacatc 147240 gcgaaatggc ttgccaaaaa gcccaaatgt gatggcttct aacatagtag acttaccacc 147300 gccatttcgt ccagtaataa gagttttttg aaccttatct aattgaatgt caataggatt 147360 tccacctact gacattatat tttgatacct aactcggttt agtttaaaat tcttcacaaa 147420 agattccttt taatgtatct tttagaccat tctatcatat catcataatc taaaaagtat 147480 tcatcaaatt cagccgtgca aacaacgcct tgtgctgctt ttgatgtgat ataaattatt 147540 ccaacatatc tagaatcttc ttcggtgtaa tcaatatttg ctatgaattc atcattaatg 147600 tcaaatgtcg aaaacttcac agtatgcatc cttaatacaa gatacagcca tatttcgtaa 147660 tgatttaggt gtgtcattat ctaaaatgtt gaagttaaaa gatacagccc agtcagtgca 147720 gactgtaacc tttttaatac aattatcttc aacttctagc ggttcaaacc agtattcaat 147780 aatttcttta tgcccaatat catcttttac ttcgcattca aaatgctgac tcatcataac 147840 atttttaaat tcatcaaaag tcattgtgtt gcctctacat atagctgatt tgcatattga 147900 ataagtgctt cacggtcaga atcagtgatg tctggaattg cattaatata ctcttccatt 147960 aatgtctgaa gcgattgaac ttcaacttct tcactgtcat ctgactcgac agagttatca 148020 atctttgaca caactcgtaa tgaatgcaca actttttcta gttcagattc gaacttcgtc 148080 agatttttgt ctacttcagt tactataaca cgtactgata gatttgtaaa atctttatag 148140 tcaatttttc ctttaaatgg ataatgaatt ctacgatgcc aggtagtatt gtttggaata 148200 aattccattc gttctgtttc tgtatcaaac atccagaacc cacgagggtc attctcgtca 148260 ccggcagtta gtgtccatgg tgtcccaata tatctgacgt tagcagcctc agagatagta 148320 tggaagtgac cagaccacac ctctttataa gtcttaagga aatcgggttc aagaccatga 148380 gatttcattc ctttataaaa ataaaatcca ttcagttccc agtgaccaac acaaaaagaa 148440 gcagatgaag ttttgatgtg ctcaagaatt tcaccagtat tttcttcgca catccaagga 148500 attaaatcaa tcaaacatcc gtcaaaatct actgtagtag gcttatcata tactttaaca 148560 ttaggatatt tagccaaaag ctcagtagag gcatttggat gcattacatt tttgtagtgg 148620 agatcgtgat ttcctacaat agtatgtaat gtgattccag cgtcatcaag catttgaact 148680 atttcacggg caaactccat agttttatgt gtgattgctt ttcgcacatc aaaaatatca 148740 ccatattgaa tccatacagt aattccattt ttcttagaat attctattgc ttgtttaatt 148800 ccatcaattt gaataccgcg aatccactca tcatcagctt taacgcctaa atgccaatca 148860 cctaaattta aaattttcat atatcaagaa ccgtcattga aatgcaaaat aaaattattg 148920 aaataaatcc atctggagtg ctaaagaacc caatccaaca tgctctagcg aatagataaa 148980 atgcaagaaa aagtatcaca tatccaagaa atatcattat atcaaactct gtataaagct 149040 aaagggccga agccctttat tttgtaataa tgtcaaactg ttctttaaag cagaagcttg 149100 aatcttgatg ctgatacaaa aattcatatg ctttttctcg ctcacggtca taaagagctc 149160 ggtcagatga cagttcttta atacgctcga atgttgattc catgtcattt tcatcaaacc 149220 aaatgatacc gctatcatgt gaggtcaaag gagtattatc aacacggaat tttaaattat 149280 cacctgttga tttccagaaa acaggaattg taccgcaagc acctaattca agatgagtat 149340 attcgagtga gcgttgtaag tatttctggt taagtttact caactgatat ccaaagccag 149400 atttactcat tcgttcaagc atttcactat taatataaca atctaggatt tgtgccggtt 149460 gattcggcgt gagattcatt ttatcaatct cacgattacc ataatattca tacggaatac 149520 ctttttcctt aattgcaata aaagcagggg aacgttcaag accttccatt acagtggatt 149580 taccagcagg ttttaagaat ttttcgtgaa aatcaaacat ctgataaaaa cctttccatg 149640 tagtcgtacg accaatccaa cggttgatgt tcatgttaat ttcagaaaca tctttccaat 149700 aagttgaccg aaccttcgca atatccatag gaggctgaaa attatatact gttggtgctt 149760 cttcaatatc atcaaacaga gaaacagttt ctggatacca ttctttcatc agaactttat 149820 taaaatcgcc attatcagaa tgactaaaaa taacatcagc tcgacgaaca gtttcttcta 149880 atcccaaatt tcgacgcaaa gaaagaacag aatgatcatg ctgataaact acaacacgaa 149940 tagaaggttt aatattatct aaaagttttt tatagttatt aatcgtggct tcttgaacgg 150000 aagtagcagg aacagaatta ataattagaa tatcacaatc attaatcagt ttaagtgctt 150060 tatcgtattc tttagctaaa ataactggaa ttgaaaatga tttgtggtca tgagaacttg 150120 tacgagtaaa tgatttatct ttagcataaa ccaaagttac ttcatgacca tttttaataa 150180 accaatcacg ctgctcaaga gaaaatttag ttacaccaca accttcaaga ccccgagcca 150240 gaaaaatgca tactttcatt taatatcctc attgttttgg tttattttac caaaaaattt 150300 ataaagcaat ataggagccg aagctcctat ccgcataata cgcccataca aaggctcgtt 150360 agagcttcta aatttttata cgcttatatg ttatagttcc ttctgcttta gctttatcat 150420 gagactcttt aaagcgtctc atcatttcta ctttagagga acgaatttta ttataatcta 150480 tttcagaagt ctggtgttca tctttcataa ctgccaccat tttttgactt gataagaatc 150540 aacccacact ttcatattag ggtctgctct tacaatagga ggattaactt ctttaattga 150600 actatcgtgg tattcttttt cagaaatttt cacgcaaaga tgaccgttca aagattcagt 150660 aaatcctgca ttaattttaa gacgcttgaa ttttacgtgt gtaagcatca atcatatcct 150720 caatctgcga tctagtagtc ttccaaagaa tactgatgag ttcatcgtta tatggctgtt 150780 ttagaatatc ccgacttttc ttgatagcat actcgtattg agcaaaatta ttattttcag 150840 ccgcaatctg agcgtgctta taaagacgat tcagttcgcg tttgttttta gacaataact 150900 tatttgcttt tctttctgct tcaagacggt tcttttcttc aatagaagaa ataagctttt 150960 ccacttcatc attaatttcg ggtttatcag tcatattatt tctctaatat aaaataaaaa 151020 tcatcatctg ttaaatgata ccgatagttt aattctacac cattagattt aaaagcggta 151080 tcatacggat tttctggatc aatatcaatg tcaagagcta aaacttccct gagatacatt 151140 ttaagtaaat agggaatagc ttcaacttca ggtatttctt ccaagaatcc ggagaggtta 151200 atcgttagcc tcatataaaa aatccaaact aggagaatcg tctacaacac ttttcttttc 151260 agcccccggt gttctatagg ttgattcttc gtaatgcgtc attttatcgt agatgtcttg 151320 aataaaagtt tcatctacta acgcaaccat atcgtcgtca cggctgtcat agacattgtg 151380 aacgaagtaa ctatatttct ttgcaacttc cttacgttct tttttaatac gttggacgaa 151440 tgcattaaaa caagcttgag ttatatacgc atgtgggttt ttatatttcg tttcatcaaa 151500 attatgaagc cccttaatag aagcttctat accatctgca atcatttctt gtttccaaga 151560 ctgggtgtat cctgaaaagt tgaaacgttt agataagcct tctgcaataa gcataatggc 151620 taatccgata gtatcattct gacgaactac tttatttggg tctttattat ttgctaattc 151680 tgttttccaa tcaataatag cttgtaaaag ctctttattg tttacgtaat tatatttagg 151740 cttagtttct gacattttca cctcttagct caattcatag atctattata tcataatatt 151800 tgaagatcta tcttaaagca tagaggatat cagttatcta agtaaacagt atgcttggaa 151860 tactttctcc atcatctttt taaattcatg aatatctata taatgactag ttaaatcagc 151920 atgatataaa aagtctaaaa acttttcatg tgtgctaaca tattcacttt catttaattc 151980 agaaacatga ctttcccaat atccaacacc agtcttattt gggaaaaatg aaattttcat 152040 gcattggtca acatagaaaa tgccataatt ttcaatagta atagaaatat taataaattt 152100 catacattca tcaacttagc cgcttcaaga gctgcatcta gtgaatcaaa ttggtcaaca 152160 tattcaatca attcgccgta attagcatat aaccaccatt ggctaaattc atactcaagg 152220 atgaatccgt ttccttcaat ttgagttaaa ccaatgccat ttgtatttac ttcatatcca 152280 gcaagacgca aatcgttaat aagagcttcg ttcataatta taccttagta attttcaggt 152340 ctgcaaattt tttcttgcgt tgatttttca tgcgacgaat agttttatcg gaaatttcat 152400 gcttttgata agctttagat tctacaccaa aagctttaac atcaaattct gacaagatat 152460 attgaaccaa caattcacgg acagtattgc gtccaatctt ctgatcattc tgtttcatca 152520 tctgatgaag ctctttttcc catttatcca aaatttgagg agttacaata tcgccttttt 152580 ctagcaaaga aactacttta tcatatgcgt aagaattaat gacgttttta atttgaatag 152640 tcatacatta tcctcaatta cgttaaaatt ttattatcca aaaagggccg aagcccttag 152700 ctaaactttt tggcaccctt ccagccttcg tacatcattg cgactgacaa tgacaaagct 152760 ccttcacatg ctgcatactt attattccag aaccaattta gaaaaacttc atcctcaata 152820 ccattgtgtt tcatgttctg gaaaaatttg gcgcgttctt cagcaattcg ctgcgataat 152880 ttagattcag gattcattta aatttcccaa ttaccatttt catcaataaa tttaatccag 152940 tcattgactg accacttggt cgtatcgcct tttggagtaa catttaaagt atataacccc 153000 tgcttaaaaa gcattcgttt gatattcata ttttcctcag ctgtaacgat agcactcgtt 153060 tgatttacgt ttagcaactc gttgagaaat attataatca aaatcatcgt caatgtaaac 153120 tgattttttc aactttctta cttcaccgcg taattgacga tttaactcat ctttaacttc 153180 tgaatcaata cctttcattc tacgccattt atctgagcga aaaatgtttt caaccatatc 153240 tttatgactt accccatcag gagctttacg ctttccgaaa tagtcataat cacgcacttt 153300 taagtcttta cgacgatacg ttttacccat agagtttaat ttccttagca actgaactaa 153360 atacagcacg gtcacaaatc atgtgtttat gtaacttaag tataagataa taaacatcat 153420 aaccatttac gtaagtaacg cgaacagcat taccattaat aagataatac tgtccctttt 153480 taatttcttt atcaatcata accatatcaa ttcctcaaag gcaattcatg tgttaataat 153540 accacggttt gaacttgttg taaacaactt tgtgaaaata ttttagggaa tgataagaaa 153600 ggaacgatag cttagaatgg taatatacag aatgtaagaa agaaaggccc agagggccta 153660 tcttagtctt ctatgatatc tctatcatat ccaagtgaaa tgagggtttc tttgaagtgt 153720 ttaatgttct tttgtctaga atcattaatg aaaatgactg gataacgaat gttaagagat 153780 gtaaatccag cgcgtttagc aagagataca atcagtggac gatcatactc aatcttacca 153840 ttatttgtaa gaactttata gaaagtaaaa ggagcattga gctcctttag aagttttgta 153900 actgattgac atccaggaca acgacctact tcatctggaa ttccatagac ttcaatctta 153960 ttctttaagt tcgagttttg ttccacgaga aataattcct tggtaagccc aataaggagg 154020 attaacagaa tcctcaccag agttttcttc aggaaaataa acctggataa cgaagccgga 154080 ttcatcaaag gtaaaataaa ccgtaggcag ttcacctaac aaatcggcac gagcgttgat 154140 ttcttcgagg tcttgttcac gtccagccca gaagcttggg ttcagactac attcatagaa 154200 ataatagtca ttaccgaaca tatcaaaacc attccaactc tctactacat accgctcaaa 154260 actaatcata attaatcctt tttatcaaga accgcattca gcttgttagt aattttatcc 154320 agacgctcat tgaactcact agaagataaa cctttttctg gagaaattaa gctaatcacg 154380 aaaaatatag caataaaagg aataaggaaa atagctccaa ctgccataaa cagaaagaat 154440 gttacagttg taagaaaatc agctaaacct ttacgaaatt tatacatatt ttatccttaa 154500 ttaattaacc aagcattgat aagtactaaa ctatactgcg aataaaattc tggaccaaaa 154560 tgaaaaatca tatcatttat agtatccata atgtaattca atttaatcat gtttccacac 154620 cccatcggta tttgaccaaa gtcgctgatt atctgatcct cgccacaact ttttagtcgg 154680 aagatttttc tcatacttcc catcaataat aacatcaaca tatttaagca tttctagttg 154740 tttaatatct tcaaacttat atcctgtcca caaccaaatg cttttattgg gataaagatt 154800 tttaatagtt tgaaccacag agtgaatcac gtctctgtta tcaggataaa gagggtcacc 154860 tccagttata gtcaatcctt ctatataatc attattcaaa cattcaatta attgctctag 154920 tgtttcacca gtgaatggaa taccatttct agcattccat gttgatttat tataacaccc 154980 ttcgcattta tgcaaacatc cagtaacaaa aagaacggtc ctgcacccag gaccattaac 155040 aaaatcgcaa ggataaaatc tatcataatt cattggtgtt taaccctatg catgatttct 155100 ttatttttac cgagattaaa tccgcgttcg ttcgggtttc caagatatcc gcatgttctt 155160 cttatggtgt tcatcttttt aggatcagtt tctccacaaa tagaacaaac aaatccgttt 155220 tcagtaggag tcatttcatg ggtacttcca catgtaaaac atttatctac tggcatatta 155280 acaccaaaat aatctaaatg ctgtgcagca taatcccata cggcctcaag accttttaag 155340 ttatttttca tatcaggaag ttcaacataa gaaatgtgac cacctgtcgc aatgaaatga 155400 tatggcgctt cacgagaaat cttttcaaac ggagtaatat tttcttctac tgaaacatgg 155460 aaactattag tgtaccaacc tttatcggta acatctttta cgcttccata tttttctgta 155520 tcaagtttac agaagcgata acaaaggttt tcagcaggag tcgaatataa actaaaagca 155580 aatccagttc tttcagtcca ctgtttaaga tgggcattca ttttagttaa aatttcctgt 155640 ccaatatcac gaccgacaag aatattcaat tcatgaatac caatgtatcc tagggacact 155700 gaacttctac cgtttttaaa taactcaatt atgtcgtcat caggtttaag acgaacccca 155760 aatgcacctt cttggtaaag aataggagca acagtagctt taactccttt taaggaacta 155820 attctacaca tcaaagcttc aaaacacaaa tccattcgtt cattgaacaa ttcaacaaat 155880 ttctgttcat tgaactgtgt tccaatataa gaatctaatg cgatacgagg aagattcagt 155940 gttacaacac caagattatt acgtccatca agaatttcat taccagtcga atctttccat 156000 acctcaaga aactacggca acccattgga gaaacaggaa cagatgaacc agtgatagct 156060 ttattattct tagctgaaat aatatcagga tacatccttt tgcttgcgca ctctagagca 156120 agctgcttaa tatcatagtt cggatcgtct ttgtaaagat taacaccttc ttcaacaaac 156180 ataacaagtt tagggaaaat aggagttatc ccgtcacgac caagaccttt aatacgattt 156240 ttcagaattg ctttctgaat cattcgttca gtccagtcag ttcccgtacc aaatgtaatt 156300 gttacaaaag gcgtttgtcc gtttgaactg aataacgtgt tcacttcata ctcatacgcc 156360 tggaaagcat cgtatacgtc tttttctgtt ttagattggg cataattcaa cgcatcagcg 156420 atttgccatt tttctgcatc ctcaatatgt tttgcatagg tgcgtttaac ataaggagaa 156480 agtactttat ctacattcgc aaaagtcgtt ccgccatatt gatgggaagc aacctgcgca 156540 gtaatttgtg ccataattgc agtagcaaca ccgattgatt taggagtttc aatctgtgca 156600 ttaccaagct taaatccgtt ctcaagcatt ccttttaaat ctactaaaca gcaattagta 156660 aatggaagag caggggaata atcaatatcg tgcacgtgaa taattccgct ttcatgcgct 156720 ttcataataa aagacgggac catatttttg gcaatgtgtt tagacacaat accagccata 156780 aggtcccgtt gagttggaaa aacacgagaa tctttattag cattctcgtt taaaaggtct 156840 ttattagttt tatgaatcaa tccttcaatt tctttttcaa ttgtcatttt aaactctttc 156900 taagctgctt cttaaatgaa gctattaatt gtgttttggt gtcagattca ttatattcaa 156960 atcctctttg aagcatctca gccatcattt cctcttttcc taaacgagaa aattcctttg 157020 atttatctcc aacgaagtta gggtgaatat tattttgggt gtaatcggat tttaaataag 157080 taagtaaatt ttctaaccat tcaagataat caacaccttg tccctttaag ccagaacgat 157140 taaatttgtg cttcatttga ccttctgcgg cattgcagag attacaaagc aatccacgta 157200 cctttcctgc ttttggtcca tttaattcat ggtcatggtc aaggtgatta gcttgaacgt 157260 caggatttag ttctcgttgg caaattaagc atttaccatt ttgtgcatca taaaatttct 157320 gtttttcttc tttatataat ttgccagtca ataacataat aaaaccctta ccttgaatag 157380 ataagggtat ttattatttt caagtattgt aaaacattcg atgcaatcgc ttatattgtc 157440 gaatcatctt tttagtagga cgagaataag ttcctacaca agtggtcata ttagggtcag 157500 taggacttcc tttaataaaa agtttccaga ctttaccgcc atttaacttt tcagtataaa 157560 ccaattcggt tttcattaaa atgccttgtc agaaaaagaa ttttgagttt tttcaagtat 157620 tgtaaaacat ttgattcaat cgcttatatt gccgaatctt ttggtcagaa aaagaaattt 157680 gagtttcaag ccattcaatg tactctgcgg cagcttgcat taaatttcct tcataaccat 157740 cgttattttc ttgtgcagct aatttagcta atgcgtatga aatacgttca ccttgaaaag 157800 cggctttagg cttctgaaca tcttggctag ttctctctac aacttcctcg atttcaccat 157860 tttcaacaga ttcagtattc cacaaacacc aatacgtaat tggcttatca tagatgttaa 157920 taatctttcc gtcggaaagt tcaatttcaa taattccagt gtcaggctct atatcatctt 157980 cacattcttt tgcaagttca cgaactttaa agacagtacc tgcactaagt tccggccagt 158040 aattacatag ccctgtatca acacgattaa ttctaaacca cttatctact gtaatcatgt 158100 cccatctcca tatcaattat gtcatttatt gtaggttcat tatatactgt ttcttcatca 158160 gtgtaaaccg gttcttccgg ctctggctct acagtttccc atctatccgc ccaccaaggt 158220 ttaaccccga agcttattaa gttcttcata atcaatccag gattctaatc ctgatggcaa 158280 atcagattca atttcccaaa gaagttcttc aattttatga agacgatcta attcttcagc 158340 tggaatagta accattgatg gagttcttga tacactaata tcgtaaatca tatttacccc 158400 agtttgacca tgcaatcgcc gtatttccac ttagaaatag acttttcgcc attagaataa 158460 taaacttcga gtttagcacg gttattttta atttgaataa tctttgctgt catcaaagtt 158520 ccatatccat agtaaactgc aacttcatca cctacatata ccgcgcttcc acgataatca 158580 tggatataat cagttccttc gagcatcatt taaagtattc ccgcaattgg tcaaatccac 158640 caatatgact tccatcagga gcaaatacct gaggcattgt caagccgatt tgagtatcac 158700 gacctagttt agtcagaagc tcagcaattt tctcatcatc aaaaacacct ttttccggca 158760 taatgttgat aaattcaaac ggctgtttct tcacagtcaa gagacgtttt gcattatcgc 158820 aatacacgca tttgtggatg ttgctatcat aaccatatac tttaaacata ttattcctta 158880 attcctagta cttgtttaaa agtctcgtcg taatcaagac tttggcccgt ttgttcttta 158940 tgtttgtata taatatcact tacttctgat agcatatttt tatatgaacg agttaaagct 159000 gatttaagca cgctgtatct atcaggaaat ttaccgtgtt cattataata agctattgct 159060 aattcacgga ctgccttttc agcagtctcc atatattctt tacgcttggt cattttcttc 159120 tcggtcaaat cggtgtttac aatgacgaca tttataacga agattactag tctgccaatg 159180 gaccaattgc acctgttcag ttccacattc agggcaatta ggaacgtttt tagaagccct 159240 ttcacgacgt tcaaccatga ccattacaga atcccaatta acaggagggc tataatcatc 159300 acaaccatga atctttccac gcatttccag atcgtcttct tcaccagcca taataatttt 159360 aattagacta gaattacttg aagctgcaat gtcttctaat agacgctttt tcatttcaat 159420 acctcaatag cattgcgtaa accatttgct tttgcattaa gagcttttaa caatttggtg 159480 tgttctgcaa tttgggcttc aacttcaatc aaacgagcat tgagatattc gcgttcttca 159540 ctcagattat cagccttttc tgctttaggt tcttttacaa cttgcttata tgtattaggg 159600 ttcttcagtt taattagaat gcgtgaactg tacagcattg aaccattatc ttcggtttcg 159660 tcatacattt ccactacgtc catcatctcc accatcgtgc agagtttata agacaacgaa 159720 cgaataattt tgttgtgctt attaatttct ctagctgtca tggtgccgag attacgtgag 159780 taataataag gaacctggat attaattaat actgatgaac cacctggctt gtgtgttact 159840 tcatcagcaa taacccaatc cttaacatga actgtatttg tacggtcatc gcccgcggta 159900 aatagtttac gagcatgctt aaaaagcata ttcacttggt cattgaattg acaagcgaat 159960 ttatcagcaa atttagtttc gggaatggta gataaccaat cagccaaatg ggtcttttta 160020 acatcgttaa caatagtaaa ttcaaccaaa tcggttatag atgtctcaga tttaatgaag 160080 ctcggcttca taaagttttt aatgttatca ctagctacag tagaagataa cagacgagaa 160140 cgtttaaacc attgaagcaa attgcctaac gaatgtgaat acgcattttg tgtatcttta 160200 caaatatggt tttcccatcc aatatagtct aaaaaatcac gaagaatatt attgattact 160260 gctctgtgtc ctatctgata attacgatgt ttagtaataa gactgtcaaa ataatcaata 160320 taatgtttac gagttttcat gttcttctca cttggttaat gatttatact ccgagccatc 160380 cttggcttta aattacttaa ttaactgtaa agcttgttcc agacgatcaa gacgattaac 160440 agattcttcc caaatccttt tagcctgctc atattctttc tgcgctttat tagaaatttc 160500 tagaacttct ttataagctt tttctagtgc aataacttct ggacgaattt ctatcggttc 160560 aggtgaatta tcaagacatt ccattagttc ctcaagggta gtttcttctt taggagtatt 160620 cacaatttca tcacattttt gttggtaaat ttctttatca gttagtgaat aagcacattt 160680 cacttcacga aggctaatta cgagtttata tccttcccaa ccgcatatat tcttaaaagg 160740 atatgtatga atattttcta ctgtttccat acaaagtaat gcggtctcta attgatgagt 160800 tatagtgcta gcaattgaga aaaatttatt aatattcttt tggttagttt ctggtgtaaa 160860 aaatctgtaa ttaataaaaa tagctacttt gtttttatca agctcatatt cttctgctat 160920 aatcatatca tcagctaagg gatgaattgt acgataatca ccataacata atttagaagc 160980 tgattttaga atttgcttcg taaaactcct aaattcacta acccaacgac gagtaaaaat 161040 attctcaggg tcttctttag tattaagatg ataagtatta acatcaccga accaattata 161100 tcctactaca tctttggttc gtttaatttc tttcccaaaa ttaccaagaa tatcccgatt 161160 aaccaaatat gaaagaagac gagactcttt aaaggttttc ttgataagat ctttatctac 161220 acggctagaa attttacgaa tttcatgaat aaatttagta gaagaaacaa tacttgcatc 161280 aacactattg agccattgat tgataataga aagaacgcta ttttggccaa acatcggtat 161340 agctttatca tcaataacgc tattgaatga tttgatatat tcgttacgag tcataataat 161400 ctcctcagta gaaagtaaaa acattatacc acatccttgt ggcaaagtaa actagttcag 161460 tgcatttagt gcattgttca gtttagaacg ttgctttgtc agattttgaa cccttgactg 161520 agcttgtttt aacacctttt cagcttctaa cacttcattg gtcgctttaa cgagttcatc 161580 atctactgcc ttaagagact tctcaatcgc gtcagcgtgc catttttcta caggtttaaa 161640 atttgaattt tcagtaggaa gaaaactcac tttattaagt ttacatgcat ctatattgct 161700 tgagctatac atccaaaatt taggatcgtt tgatgagtaa ttagatgaat ttaaggtatt 161760 ttgcacttcc tgctttttct cttgaacaat ttcatccttt ctcaaaaatt catatttaaa 161820 tgaaacgatc atatcaagtt catatgttgt tgtatgttcc caatttcgct caaaatgagg 161880 taaaatctta gattgaacag cagcaacaac atccatatac ttaaatgctt ctgtcagctg 161940 tgatttaaga cattcacaaa ttgaaagaga attttttgta ttaggtttaa agctaattcg 162000 tgcagttcta ttattttctt ttaatggtct tacttccatc tgaagagtat aaccatcaaa 162060 tttcaggttc tttaagttaa tgtcagaacc ttttaatcga ctcgcaattg ataaaatttg 162120 ttttaattgt ttacggaata gagcaataaa tctccattca atacgataat gatttggatt 162180 gaaaaatcca gatgataaat caaccttact ttggccaacg cctcgaacaa atagaggatt 162240 tttataatca atagttttac agaaatcggt gagctgttca cgagcagtca tttgtgtaat 162300 ataccccgct ttactaaaat gacgtaacca ttcactgcta ttcgtatact taaagcgatg 162360 aataacacga ttaactttat cagggtctaa attattttgg cacaaaaatg tcataacatc 162420 acgagtataa ctggcattac gaaccatatc ttcaatttga gaacgagttt tcatggtgtt 162480 ccttaagatt taagtaaatc aacaatttta attaattttt cacgttcaga tttagcttta 162540 ctactcaatc cagatagtct gaaaatttca tcatcatatt gctgaataga aatattcagc 162600 tcttcaatct gcttattaaa ataatcaatt tgttcagaat gtttttcgtt actacgaact 162660 gatacaggtt ttgtaggcaa tttagttgaa ctggattcat ccgggcgata aattaaaata 162720 caatttgaac caatagggca ttttgcacca gacacatatt ctaatgttcc ggcttctttt 162780 aaaacttcaa aagctaaaca gagatgatgc cccatattaa cataatctgt agagcgagct 162840 ctgacgtaat aatcatctcc acgagtgcta aatttaaagc atttaaggtc ttctgtatta 162900 ttggtcttaa aaatcatttg tttatctaga cctttagcta atcgagcacc taatgctaat 162960 aatcgtcgtt gattttccca caaatccgca atcatttggt cgaatgataa ttttggcatt 163020 agtcgaccat aaaggtcata tcctttatta taattacgaa ggatttcact cgcgttaatg 163080 cgagacaacg ctccaatttt attaagggct ttcatgatgc gattagataa aagcattcca 163140 gacccgtttg ttcgttgtaa atgtttttct aatccaaatc caatatcaac tttaaactta 163200 tctaaaattt cggcgtgaac atctattatcg ataacattta aatttagtac tgggttaaat 163260 ttatgaaaaa atttatctga ctcgtcgcgt tgaagtacaga tccattcatt tgatttttta 163320 ttaactaaag atttaattac tgcattgaca ttattaattg ctactgacat attttcctca 163380 ctcaatttca attttactaa atatacagaa taagatagaa cagactatat aagcaccaca 163440 cacagattga actaatacca ttccaaagaa ccaaacaaca ttatcaaaca atgtctgttt 163500 tacgtcaaaa ggacgtaaac ttacagtaat attatcacct ttttctattg aagaatacat 163560 ctctggggaa atatattcac taaatctata accgtctttg agttcatata cggcaataaa 163620 cgataaacta gacccctttc cttgagttcc tgtaagggta ttaactacag taacatcata 163680 atctttataa tgcatataat cattaattgc gtaataacca tatgcaacta ctacacataa 163740 acaacatatc aataaattca atcttttaat tatcaactgt ttcataataa tctcagttaa 163800 aagggcttag aaccattata ccatccttgg tataaagcgg ttatgcgagt accgtcttta 163860 accgttcttc aaatttccga agagtgttct ggcgttcagc tctttgcttt ttgtaagttt 163920 caatacgctc tgaaatgaga gcgtatcgtt catttactga ttctttcata aaatcaggaa 163980 tttcacgaga agctttaatc tcatcaaatt tatcaataac agcttgctct tcagcaatta 164040 agttatcata cattaaaata tctttcttga taaactcaat atcttcttga gttacacgag 164100 ataatttaga tgctttatcc tttttgtact gttcgttagt atcacgagac cagtgtaatg 164160 tacgattttt attcgtattc ttgtaaattt ctacaatacc gatctcatcg ataataacga 164220 tccaattcca acgggatttg taaatttgtc ctccatcaac agtgatttca cctccgattg 164280 agatgtcatt aaagaacttg ctttgtgctt ctgatttaaa tttaccatcg ttgtaattta 164340 ccaggttgaa aatatcttta gcgttcattt tgtgctcctc cgtagttgat agttgtatag 164400 taccacagag gaacggtctt gtaaaccact aaaagaaact tctttcacaa ttttttccac 164460 tgaaccatgc gctcactgct ttcttagtct caggagcagt gttatccata aaccattcaa 164520 aggcagcctt tttatgattc tggagggctt ctcgggcttt aatctgctca cggtctatta 164580 acactaacat atgagccttt cttgtcacca ggggcttctt atgatttttt gaatactccc 164640 aatcatttgt ccatcgcatc gttgttgcga attgaagtac agcttcttta atcttagttt 164700 cgtaaatttc acgagccttt gagtataaca tcattacctc catttaccag tttaattcta 164760 gtcatctttt taatggcagt ccatataatc tatttctgaa ctgccttttt gtcttagaag 164820 tcctcttatg aatttatttc agaagagtaa cctcagcgat ttcttgccaa ccgtttttgt 164880 cggtcataat aaagtcagca agataaagtg cagtacgcag tgaaacatta cgtaaacggt 164940 taacattgac tttcatccat gataatgctt tataagtttc ttcatcagaa agaccgcgct 165000 tttgcatcat gtcagttgaa agaataacat cttcaaccct gaccataatt tcttcattag 165060 tgtgaacacc caaatccaaa taaaccgagc gggacactaa tgcttgtaaa tgtggagcaa 165120 gtttagtacc acggtctaat tcgcggtcaa tgtcaacgtt tgtgataaaa acaatcgttc 165180 ctttaaattc aaactcacgc tcaatgcctt tttcttctaa gtaagaagac gcagtgctcc 165240 agcagacttt acgggtctct ccagtgtcca gagcggcttt tagaagatta agaatatcca 165300 tatcagagaa aacatccaca tcatcaatca aaaggacaga attctcttca cgattattcc 165360 aaagctgctc ataaagacca ataccagaga ttttaccatt aatgctttta tattcaatgt 165420 atccaatatc atttgcttta tttaaagctt tatctaaaga atacgtttta ccaatacctg 165480 ctgcgccaga gataattaat gaacgaatat ttccgttaat aataccattc gtcatcattc 165540 ccataacatt aaatctttta ttaatgcggg ttttcatatc ttcatatgat tctttaactt 165600 cttcaacttt tacaccatca tatgaaatat ctgatttgta aacccaaaca ccgcgacgtt 165660 taccgtcaat ttcaacaaaa actttaccat ctccttgtgc atctaccgga gcattatctg 165720 ggaaccattc tcctaagagc tcaaaagttc cagagatttc tttaccgaag tagataccct 165780 tattgatagt tacagttttc attttattct ccaatttcac atttgttttg atagggtaat 165840 agtatcacac tactacccta ctgtaaacaa tttattttaa tgtttgccaa atttttactg 165900 cttcgcgacg agatacttct acagctccaa gttctacagc tttttggcgt cgccgagcgt 165960 gtaagtcata atgtttaatg cgtttatctt gaaaccaaga acgtttcatt cctattgctt 166020 ctgccatttc gtgaagctct tcaatatctc catcagtgaa catatgacaa tttttagttg 166080 gatgaccgcg aagtttccat ccatgattca ttaaaacatc tacgtaaact gtcattgatt 166140 cttctccaaa taagtttcga taattttctg agcgagataa actgcattat cttcagttgc 166200 atcttctaag aaactttcaa aacactctga aatttcttct gtgtcaatca acttttttac 166260 ttcaattggt gtaattttca ttttgttttt ccgtttaagt gtttgttttg atagttgtat 166320 agtaccataa agctttatgc ttgtaaacca ctttgtgaaa aaatttttga aataaaaaag 166380 ggagcccgaa ggctccctat catttataat aacttcggtg gttttcaaga tagaccttct 166440 caaggaagtc atcccagaaa ctcatgtcta ctgttttagg cataccgttc ttagaagctt 166500 cagtagatgc tgcttctact tgatcgacca catcttccaa aaactcttga acggttttaa 166560 atggatgttt acccaacttc acgtcgagaa taaatggagc gtcttgaagt ggataaacca 166620 agtcaccagt tttgtaaatt tccaatagtt ggagtccacc acgacaagca tgactcagag 166680 ctttccagtc aatgccttca ttggcttcgg ccttacgagc gcgttcaccg tattcagcat 166740 ctaatttgtt cagtgactgc ttaagctcaa taagagaaag cgttgtctga tatttacgac 166800 ccaacactgt gtaaaacgtt tgtggacctg ttttctcatg attatggaac acccattcac 166860 agaattcatt ttttggaaga cgatgcttaa tatcttcaac tttagtgcgg cgctgcttaa 166920 tagaaccatc ttcttggtaa tcaacccatt gctcggggat ttgattaact actttcaata 166980 catcacgtaa tgcagccaaa cgagaaccct taacaccgta tttagaagct tgtttgcgga 167040 catatcctaa ataggatttc atgttagtcg tataaaaacg agaacggttg tcttgaataa 167100 acttccacac atcaggcaaa tcagatttaa ccactagttc aggtggagtg tgaagcatat 167160 ccaatgctac agtttcacca tctgctgcta atttaaagaa atacttaaga ctatacaatt 167220 cgtggtcaat atcatcttta gtgtttttag atgatgtgtt gttggtgttt ttactcatgt 167280 gctctttgac atttccgata agaatatcac gagcaggagg aacaaagatt tctttaaaat 167340 ctacatcaga ttctggggta gaagttccat aaagatgact accaaaataa cttttcatta 167400 ctgttttcat cattcagcct tatattcaat aacaggacac actttagctt tacgagcttt 167460 taaaaattcg acgataatcg atttcttggg ttgaatagga ggtaaacctt tatacgccct 167520 atcaatattt tctacgtgta aagcataatc ctttttccat ttataatctt tatatttttc 167580 acgcaaatgt gcaggaataa caaatgaacc gataataagt aaaacaacca aaagcgcaag 167640 tataaatgct gatggaataa gagtccataa actaccaaaa ataagccatt tctgtatgat 167700 ttctgcacag atgatagtta gacctacgag tatagtacat ccgaaaaaag aaacgaaaaa 167760 tgtaggaatg gcaatagacc aaaaatatgc gcatagtgtc ttaggtcgtt gccattcatc 167820 gttaaacaat ttgaataatt tatagtgcca agagttttca ttaataatca taattatcct 167880 ttcattgaag gtgtaacagt tgttaaatac ttaatcatag cttcagcttc tgattttgat 167940 aatgaaattt ctccattgtt ttgacgaata gaaataaaat ccggatgacg gtcaccaccg 168000 gcttttaaaa cacacatata agtatcagtt tcatcttcaa tatttgaaat gattgaagca 168060 gttccacacg aatgtggttt ttgataaatc aatacagctt ttcttccacc atttgactgt 168120 tcataaactt ttaatacatc aaacaaatca cttcttttat caatagctaa aatgttattt 168180 tcatcttcaa tgttaaatcc ttcggatact tcataaagtg tcacccataa atcacctata 168240 tcgatagtag cattttcctt tccatgactt tcaagagcat gacaaatttt cttaatttcg 168300 tcataactca ttttaataat atcatctcct tgactaagaa agatgtcatt tttaaattca 168360 acacgaatta aaccgcttcc acttgaaata aacatatttc ctcactttga aatcatagtt 168420 ggaataacag aatcaagata agtctttaac gcaatagctt cgtctttgtt taatgtaatg 168480 atatgtgatc gaaaatcgtc aatttgacga atagatacta catctccctc ttcatagcat 168540 tttgacacat ttaaaatagt ttcatcattc tgattgcaag cgttagtaat aatagcattg 168600 caatttttga gccgttttaa actatgtttt ctttcattag aataataaaa atatttaatc 168660 ttagctataa aactatccca atggataact gataaacaca ttgactcact ttcaatgtta 168720 aatcctgggc atgaagaata aaaatgaatt ttgtgctcat cattgatgct tactatttta 168780 tcagcataag gatattcaat ttgggttaaa tgaataattt cactaggtgt aaaatacagc 168840 atatcgtctt cttgcgtcaa acgatacatg ttatttactt tttctatagc caattcacca 168900 aaaagcggac taacttctaa tactaatcgt ttcatattaa tcctttttat tggcacgaat 168960 ttgttctaaa attttagaat attcctttgt atcagattta cgtacaattg atacactata 169020 aggcatacta tcggtgtctt ttataaagcg ttccaaatga cactctaaca aaatttctgg 169080 attataaatc gtgtacatca aattacctgt tgctccacga tattggcaga tttctactga 169140 ttgaacacca ttccataatt ttgttaaaac taaatcacct acttctaatt taggaaagcc 169200 catgttattc accaattaaa gtttcaatat aagaatcaag atttacttta gcttcttcca 169260 taagagtttt gtatttaatc ttgttagcat gtccggagaa agctgattca tcaataattg 169320 ttgatgtatg aacagcttta ctatacgtct caattaattc tcttaattta aaagcctgct 169380 cacttgtcat tacatactcc tttgaataat atcaataatg ttgttcacca gattataagt 169440 aaacattggg taattatatt gaatcatcac atacacaaca aacaaaactt tcattctctt 169500 ctccttggca gttgacaaga ttactatacc ataaccttgc caacttgtaa accattaaat 169560 gacgttttca ataaaattct gaagctttgt gtgagcatca accatgattt tcatttcttc 169620 tttggcgaaa gctatacctc tttcccgaga agaacattca tagtcagaaa ctgcgttagc 169680 atattcttca attagtttca ttaaaaacat ctgcttttca gttttcatta ttccacctaa 169740 tcatttcaag atattgaact aacttagctt tggatttatc caaatccttt ttagctgctt 169800 ctata 169805

Claims (9)

살모넬라균에 특이적인 사멸능을 갖는, 서열번호 1로 표시되는 염기서열로 이루어진 박테리오파지 SG1(기탁번호 KFCC11698P).
Bacteriophage SG1 (Accession No. KFCC11698P) consisting of the nucleotide sequence shown in SEQ ID NO: 1, which has a killing activity specific to Salmonella.
삭제delete 제1항에 있어서, 상기 살모넬라균은 살모넬라 갈리나륨(Salmonella Gallinarum), 살모넬라 플로럼(Salmonella Pullorum), 살모넬라 콜레라수이스(Salmonella Choleraesuis), 살모넬라 엔테리티디스(Salmonella Enteritidis) 및 살모넬라 티피뮤리움(Salmonella Typhimurium)으로 구성된 군으로부터 선택된 1종 이상인, 박테리오파지 SG1.
The method of claim 1, wherein the Salmonella is Salmonella Galina volume (Salmonella Gallinarum), Salmonella Flow column (Salmonella Pullorum), Salmonella choleraesuis could device (Salmonella Choleraesuis), Salmonella Entebbe utility disk (Salmonella Enteritidis) and Salmonella typhimurium (Salmonella Typhimurium), bacteriophage SG1.
제1항의 박테리오파지 SG1을 포함하는, 항생용 조성물.
An antibiotic composition comprising the bacteriophage SG1 of claim 1.
제1항의 박테리오파지 SG1을 포함하는, 사료 첨가용 조성물.
A composition for feed addition comprising the bacteriophage SG1 of claim 1.
제5항의 사료 첨가용 조성물을 포함하는, 사료.
A feed comprising the feed additive composition of claim 5.
제1항의 박테리오파지 SG1을 포함하는, 소독제.
A disinfectant comprising bacteriophage SG1 of claim 1.
제1항의 박테리오파지 SG1을 포함하는, 세척제.
A cleaning agent comprising the bacteriophage SG1 of claim 1.
제1항의 박테리오파지 SG1을 인간을 제외한 개체에 투여하는 단계를 포함하는, 살모넬라균에 의한 감염성 질병의 예방 또는 치료 방법.A method for preventing or treating an infectious disease caused by Salmonella, comprising the step of administering the bacteriophage SG1 of claim 1 to an individual other than a human.
KR1020170170714A 2016-12-23 2017-12-12 Novel Salmonella specific bacteriophage SG1 and antibacterial composition comprising the same KR101993124B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20160177916 2016-12-23
KR1020160177916 2016-12-23

Publications (2)

Publication Number Publication Date
KR20180074581A KR20180074581A (en) 2018-07-03
KR101993124B1 true KR101993124B1 (en) 2019-06-26

Family

ID=62918758

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020170170714A KR101993124B1 (en) 2016-12-23 2017-12-12 Novel Salmonella specific bacteriophage SG1 and antibacterial composition comprising the same

Country Status (1)

Country Link
KR (1) KR101993124B1 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101070938B1 (en) * 2008-12-02 2011-10-06 씨제이제일제당 (주) Novel bacteriophage and antibacterial composition comprising the same
KR101151532B1 (en) * 2008-12-24 2012-05-30 씨제이제일제당 (주) Novel bacteriophage and antibacterial composition comprising the same
KR101151516B1 (en) * 2008-12-24 2012-05-30 씨제이제일제당 (주) Novel bacteriophage and antibacterial composition comprising the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Salmonella phage SG1, partial genome, GenBank: MF001354.1. 2017.09.16.*

Also Published As

Publication number Publication date
KR20180074581A (en) 2018-07-03

Similar Documents

Publication Publication Date Title
KR101592177B1 (en) Method for prevention and treatment of Escherichia coli infection using a bacteriophage with broad antibacterial spectrum against Escherichia coli
RU2725726C2 (en) Bacteriophages, phage peptides and methods of using them
KR101649851B1 (en) Novel Shigatoxin-producing Escherichia coli type F18 bacteriophage Esc-COP-1 and its use for preventing proliferation of Shigatoxin-producing Escherichia coli type F18
CN107109373B (en) Novel bacteriophage and composition comprising the same
KR101761581B1 (en) Novel enteroinvasive Escherichia coli bacteriophage Esc-COP-4 and its use for preventing proliferation of enteroinvasive Escherichia coli
CN110545670B (en) Phage therapy
CN112243377A (en) Bacteriophage for treating and preventing bacterially-associated cancer
KR102016922B1 (en) Novel pathogenic Escherichia coli specific bacteriophage EC10 and antibacterial composition comprising the same
KR101993122B1 (en) Novel Klebsiella genus bacteria specific bacteriophage KP1 and antibacterial composition comprising the same
KR102432624B1 (en) Novel Staphylococcus specific bacteriophage OPT-SC01 and antibacterial composition comprising the same
KR101863588B1 (en) Novel Proteus mirabilis specific bacteriophage PM2 and antibacterial composition comprising the same
KR101587113B1 (en) Novel bacteriophage having killing activity specific to Enterococcus faecalis causing periodontitis
KR101993123B1 (en) Novel pathogenic Escherichia coli specific bacteriophage ECO5 and antibacterial composition comprising the same
KR101993124B1 (en) Novel Salmonella specific bacteriophage SG1 and antibacterial composition comprising the same
KR102016919B1 (en) Novel Salmonella specific bacteriophage SC1 and antibacterial composition comprising the same
KR102203675B1 (en) Novel Yersinia specific bacteriophage YE12 and antibacterial composition comprising the same
KR102003759B1 (en) Novel Salmonella specific bacteriophage SH9 and antibacterial composition comprising the same
KR102066898B1 (en) Novel Enterococcus faecalis specific bacteriophage EF5 and antibacterial composition comprising the same
AU2021240230B2 (en) Vaccines and vaccine components for inhibition of microbial cells
KR102334893B1 (en) Novel Campylobacter specific bacteriophage OPT-CJ1 and antibacterial composition comprising the same
KR101992013B1 (en) Novel bacteriophage having bacteriocidal activity against pathogenic enterobacteria and uses thereof
KR101871347B1 (en) Novel pathogenic Escherichia coli specific bacteriophage EC121 and antibacterial composition comprising the same
KR102723118B1 (en) Staphylococcus specific bacteriophage KMSP1 and antibacterial composition comprising the same
KR102269089B1 (en) Novel bacteriophage specific for Acinetobacter genus bacteria resistant to antibiotics
KR101993125B1 (en) Novel ESBL producing Escherichia coli specific bacteriophage ECO4 and antibacterial composition comprising the same

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
GRNT Written decision to grant