KR101982697B1 - Antimicrobial components - Google Patents

Abstract

The present invention relates to an antimicrobial composition containing plant essential oils. More particularly, the present invention relates to the antimicrobial composition containing plant essential oils which exhibits an excellent antimicrobial effect on Trichophyton, namely athlete′s foot germs and colon bacillus, since the composition is composed by containing antimicrobial essential oils (plant essential oils), which contains Foeniculum vulgare oil, cinnamon oil, peppermint oil, rosemary oil, and sweet orange oil.

Description

ANTIMICROBIAL COMPONENTS < RTI ID = 0.0 >

The present invention relates to an antimicrobial composition comprising a plant essential oil, and more particularly, to an antimicrobial composition comprising a fungicidal composition comprising fecal oil, cinnamon oil, peppermint oil, rosemary oil and sweet orange oil, And a plant essential oil excellent in antimicrobial effect against E. coli.

Skin diseases caused by fungi (fungus) are collectively referred to as derma-tomycosis. (Dermatophyte), Tinea or Superficial fungal infection, which is caused by parasitic dermatophyte penetrating into keratin tissues such as keratin, hairs, nails and claws of skin, (Ribbon, JW (1998) Medical Mycology. In The pathogenic fungi and the pathogenic actinomyces., 2nd ed. WBSaunders Comoany. Philadelphia, London, toronto.)

In case of superficial fungus, Tinea manus Tinea pedis in case of hands and feet, Tinea faciale in case of face, Tinea capitis in case of tofu, Tinea crusis in case of nails and toenails, Tinea ungium or Onychomy-cosis in case of nails and claws, and Tinea corporis in cases where it is excluded. (Rezab da GH and Friedman, AD 1992. Drugs 43 (5): 674-682.: Kamalam, A. and Thambiah, AS 1976. Sabouraudia 14 (2): 129-148).

The main causes of superficial mycoses are microsporum, epidermo-phyton, Trichophyton, and candida species. In particular, white fungi have the property of invading both skin, hair, and nail (Weitzman, I. and Summerbell, R.C. 1995. The dermatophytes. Clinical Microbiology Rewiews 8 (2): 240-259)

The causative organisms of superficial fungi are parasitic on the keratin of the upper part of the epithelium and cause superficial lesions. Sometimes, they may cause inflammation even below the epithelium and cause dermatophytidosis.

Pathogenic fungi are distributed throughout the world and cause diseases in animals, including humans. The pathogenic fungus does not always cause disease by contact, but it varies depending on the type of infecting fungus, the age of host, immune status, complications, skin health, nutrition, and hormone status. (Brasch, J. and Gottehaskamp, D. 1992. The effect of selected human steroid hormones on the growth of dermatophytes with different adaptation to man. Mycopathologia 120 (2); 87-92)

Dermatophyte spp in the vast majority of the skin and its appendage infections caused by the fungus is called dermatophytosis. These fungi groups are localized to the epidermal keratinization layer, and some species invade and live in animal tissues. For convenience, it is called anthrophillic, zoophillic, and geophilic (saprophyte in the soil), depending on the host. (Gupta, A. K., Einarson, T. R., Summerbell, R. C. and Shear, N. H. 1998. A North American perspective of Drug. 55 (5): 645-674)

Treatment of superficial mycoses is based on the use of topical and systemic antifungal agents and, in some cases, application of the keratolytic agent is carried out in parallel. After symptoms and skin lesions have disappeared, treatment for about 2-4 weeks is required. However, in the case of tinea pedis, it is highly likely that the patient will fail or recur due to the carelessness, the characteristics of the body part and the immunodeficiency.

So far, many antifungal agents have been used to treat skin fungi, but efforts have been made to find more safe and better antimicrobial substances in natural products due to the high recurrence rate and increased recognition of skin toxicity.

SUMMARY OF THE INVENTION Accordingly, the present invention has been made keeping in mind the above problems occurring in the prior art,

It is an object of the present invention to provide an antimicrobial composition which is harmless to the skin and which is environmentally friendly as it contains fennel oil, cinnamon oil, peppermint oil, rosemary oil and sweet orange oil and has antimicrobial activity against fungi, .

It is biodegradable by further containing purified water, coconut oil, potassium hydroxide, castor oil, olive oil, rosin, sugar, golden extract, magnolia extract and menthol. It is eco-friendly and has a comprehensive antibacterial function such as antibacterial function, tickling, cracking, You can fix the problem,

It is an object of the present invention to provide an antimicrobial composition which contains an oil effective for deodorization and can solve the cause of odor and leave a reverberation.

In order to achieve the above object, the antimicrobial composition according to the present invention comprises

When the antibacterial agent composition is used in an amount of 100 parts by weight,

5 to 6 parts by weight of cinnamon oil, 0.2 to 0.3 parts by weight of fennel oil, 5 to 6 parts by weight of peppermint oil, and 0.2 to 0.3 parts by weight of rosemary oil.

As described above, the antibacterial agent composition according to the present invention comprises

It has a very strong antimicrobial activity against Pseudomonas aeruginosa and Escherichia coli by using cinnamon oil, fennel oil, peppermint oil, rosemary oil, sweet orange oil,

By using natural vegetable oil, it is harmless to the skin because it is not toxic, and it is biodegraded in water after washing, and it is eco-friendly.

Especially, it contains more essential soap which contains essential oil and rosin of antibacterial, anti-inflammatory and antiviral ingredients and contains soaped vegetable oil so that rinse is quick and moisturizing and clean feeling is used. It does not use synthetic surfactant, .

Handmade saponification of various natural oils to provide quick rinsing and moisturizing, eco-friendly,

Since it contains oil that is effective for deodorization, it is possible to eliminate the cause of odor and to manage the feet with a refreshing reverberation with natural reverberation.

Furthermore, since the anti-bacterial lotion manufactured using the above-mentioned composition can be stored in a storage container for storing the anti-bacterial lotion agent, the lotion agent to be filled in the inside can be cleaned and economically used.

Fig. 1 is a table showing the composition of the antimicrobial composition according to the present invention
FIG. 2 is a view showing a container for an antimicrobial lotion prepared using the antibacterial composition according to the present invention

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will now be described in detail with reference to the accompanying drawings.

While the present invention has been described in connection with certain embodiments, it is obvious that the invention is not limited to the disclosed embodiments, but, on the contrary, is intended to cover various modifications and equivalent arrangements included within the spirit and scope of the invention. It is to be understood, however, that the invention is not intended to be limited to the particular forms disclosed, but on the contrary, is intended to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the invention.

In the drawings, the same reference numerals are used for the same reference numerals, and in particular, the numerals of the tens and the digits of the digits, the digits of the tens, the digits of the digits and the alphabets are the same, Members referred to by reference numerals can be identified as members corresponding to these standards.

In the drawings, the components are expressed by exaggeratingly larger (or thicker) or smaller (or thinner) in size or thickness in consideration of the convenience of understanding, etc. However, It should not be.

The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The singular expressions include plural expressions unless the context clearly dictates otherwise. In the present application, the term " comprising " or " consisting of ", or the like, refers to the presence of a feature, a number, a step, an operation, an element, a component, But do not preclude the presence or addition of one or more other features, integers, steps, operations, components, parts, or combinations thereof.

Unless defined otherwise, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Terms such as those defined in commonly used dictionaries are to be interpreted as having a meaning consistent with the contextual meaning of the related art and are to be interpreted as either ideal or overly formal in the sense of the present application Do not.

When the total weight of the antibacterial agent composition according to the present invention is 100 parts by weight,

5 to 6 parts by weight of cinnamon oil, 0.2 to 0.3 parts by weight of fennel oil, 5 to 6 parts by weight of peppermint oil and 0.2 to 0.3 part by weight of rosemary oil, wherein 7 to 8 parts by weight of grapefruit oil, 3 to 4 parts by weight of eucalyptus oil , And 1 to 2 parts by weight of tea tree oil (plant essential oil).

More precisely, it is preferable that 5.14 parts by weight of cinnamon oil, 0.26 parts by weight of fennel oil, 5.14 parts by weight of peppermint oil, 0.26 parts by weight of rosemary oil, 3.6 parts by weight of eucalyptus oil and 1.54 parts by weight of tea tree oil,

2 to 3 parts by weight, more preferably 2.57 parts by weight, of lemon oil.

It is also possible to include sweet orange oil.

As for the antibacterial essential oil (plant essential oil)

Cinnamon oil is the essential oil which is the main component of cinnamon, Cinnamic aldehyde, Camphene, Cineol, Linalool, Eugenol,

Cinnamic aldehyde is a yellow liquid fluid which is a major component of cinnamon oil,

The Camphene is an unsaturated hydrocarbon belonging to terpenes and has colorless crystals and is used as a source of camphor synthesis and fragrance,

Cineol is a colorless liquid natural organic compound with fresh camphor-like odor, fragrant flavor and cool taste.

The efficacy of such cinnamon oil is representative of its antibacterial effect,

It is very effective in eliminating harmful bacteria like antibiotics. It is widely used for prevention of tooth decay. If you take half of a solution of cinnamon in warm water and brush it, you can eliminate all the bacteria and bad breath.

It is also used to remove mold.

Fennel oil is a Fennel oil containing a vegetable hormone similar to female hormone (estrogen) to help alleviate menopausal symptoms, promote breast milk production, and normalize small amounts of menstruation. Also antibacterial. Bronchitis caused by antibacterial and germane action. Helps with colds and coughs (direction and suction), excellent body cleansing action, eliminates overeating and overeating toxins, stressful indigestion, flatulence, vomiting. It is also good for colitis, and it is also a great addition to the relief of hangover by the action of the liver, kidney, and spleen. It is also used for urinary infection, kidney stones, and cellulite removal due to its diuretic effect. It has a characteristic that it can remove insect bites from snake bites due to detoxification.

Lemon oil contains a large amount of vitamin C and citric acid. It has antimicrobial action, which can sterilize food poisoning bacteria and increase the resistance to various bacteria.

Peppermint oil is an essential oil with analgesic and antimicrobial effects, which reduces harmful bacteria and is effective in relieving pain.

Grapefruit oil often refers to grapefruit, which, like lemon oil, contains a large amount of vitamin C and citric acid.

Rosemary oil has antimicrobial activity and antiviral activity mainly based on rosmarinic acid. It also alleviates the symptoms of pollen allergies. It is also used as a rosemary oil treatment to prevent dandruff, and it also has an effect on hair growth by activating blood circulation in the scalp. It also has anticonvulsant action, which makes it easier to suppress bronchospasm, to breathe easily, and to antimicrobial effects.

Eucalyptus oil contains a large amount of cineol, which results in strong sterilization, anti-inflammation, and side effects.

Tea tree oil has been known to have excellent antiviral effects such as antiseptic, antimicrobial, anti-inflammatory, immune strengthening, and conflicting effects. It is known to improve immunity, helps to release toxins, is effective in eliminating bronchitis and cold virus, It is excellent for bacteria, antibacterial, inflammation and fungus bacteria and is used for skin troubles such as acne.

As described above, the present applicant confirmed that antifungal oil, cinnamon oil, peppermint oil, rosemary oil, and sweet orange oil have antimicrobial activity, and thus the antimicrobial composition according to the present invention was formulated.

Furthermore, by adding the purified water, the net soap, the plant extract additive, and the additional essential essential oil to the above-mentioned antimicrobial essential oil (essential oil), the use of the chemical surfactant is not used so that the skin is hypoallergenic, Can be maximized.

Specifically, purified water refers to pure water formed by completely removing the penta from dissolved ions, solid particles, microorganisms, organic substances, and dissolved gas residues contained in water.

The net soap includes vegetable oil and the like and refers to a soap which does not contain a chemical perfume, a pigment, a soda, a safety agent, a fluorescent brightener, etc. The net soap in the present invention is composed of a liquid soap which is not solidified, Additives, antimicrobial essential oils, and the like.

The net soap comprises coconut oil, potassium hydroxide, castor oil, olive oil and sugar.

Looking at the blending ratio of each,

Wherein the purified water comprises 50 to 60 parts by weight of pure soap, 20 to 22 parts by weight of pure soap, 0.9 to 1.0 part by weight of a plant extract additive, and 25 to 26 parts by weight of an antibacterial essential oil, wherein the antimicrobial essential oil is selected from the group consisting of cinnamon oil, fennel oil, Grapefruit oil, eucalyptus oil, and tea tree oil.

More preferably, based on the following examples, purified water 52.48 parts by weight, net soap 20.66 parts by weight, plant extract additive 0.93 parts by weight, and antibacterial essential oil 25.93 parts by weight.

Wherein the net soap comprises 10 to 12 parts by weight of coconut oil, 3 to 4 parts by weight of potassium hydroxide, 2 to 3 parts by weight of castor oil, 1 to 2 parts by weight of olive oil, and 1 to 2 parts by weight of sugar,

More precisely, it comprises 11.06 parts by weight of coconut oil, 3.69 parts by weight of potassium hydroxide, 2.57 parts by weight of castor oil, 1.8 parts by weight of olive oil, and 1.54 parts by weight of sugar.

The plant extract additive is composed of rosin, a golden extract, a rosemary extract, a magnolia extract (referred to as Magnolia japonica, flower, leaf extract) menthol, each of which contains 0.05-0.15 parts by weight of rosin, 0.15-0.25 0.15 to 0.25 parts by weight of a rosemary extract, 0.15 to 0.25 parts by weight of a magnolia extract, and 0.15 to 0.25 parts by weight of menthol. More specifically, 0.1 part by weight of pine root, 0.21 part by weight of a golden extract, 0.21 part by weight of a rosemary extract, 0.21 parts by weight, and menthol 0.21 parts by weight.

The antimicrobial essential oil further contains citronella oil, tea tree oil, mayo oil, lavender oil, wintergreen oil, benzoin oil, and perennial oil. The composition ratio thereof is 0.05 to 0.15 parts by weight of citronella, 0.02 to 0.1 parts by weight of lavender oil, 0.02 to 0.1 part by weight of lavender oil, 0.005 to 0.015 part by weight of wintergreen oil, benzoyl oil and oil extract, respectively,

0.08 parts by weight of citronella, 0.05 parts by weight of Mayflower oil, 0.03 parts by weight of lavender oil and pine oil, and 0.01 part by weight of wintergreen oil, benzoyl oil and patch oil, respectively.

In other words, the antimicrobial essential oil contains 5.14 parts by weight of cinnamon oil, 0.26 parts by weight of fennel oil, 5.14 parts by weight of peppermint oil, 0.26 parts by weight of rosemary oil, 3.6 parts by weight of eucalyptus oil, 1.54 parts by weight of tea tree oil, 2.57 parts by weight of lemon oil, 5.14 parts by weight of fruit flavor, 0.08 part by weight of citronella, 0.05 parts by weight of Mayflower oil, 0.03 part by weight of lavender oil and 0.01 part by weight of each of benzoguanyl oil and phenyle oil.

First, the ingredients of net soap have the same efficacy as the following [Table 1].

[Table 1]

The plant extract additive has the same effect as the following [Table 2].

[Table 2]

The antibacterial essential oil has the same effect as the following [Table 3].

[Table 3]

Table 4 below is a table showing the respective components of the oil.

[Table 4]

In addition, it was found that the essential oil through the antibacterial composition of the present invention exhibited excellent antimicrobial activity as a result of measuring the clear zone of the pycnogenesis causing athlete's foot and applying Escherichia coli causing food poisoning (see Table 6). )

Furthermore, the antimicrobial composition according to the present invention has growth inhibitory activity against pathogenic fungi and bacteria, and preferably has growth inhibitory activity against pycnotoxins and Escherichia coli.

The antimicrobial composition of the present invention has an antimicrobial effect against pathogenic fungi and bacteria described in the following [Table 5]. A representative pathogenic fungus is Trichophyton rubrum (ATCC 28188), and the bacterium is E. coli (ATCC 25922).

[Table 1]

The antimicrobial composition according to the present invention can be used for inhibiting the growth of pathogenic fungi. Preferably, it can be used as a therapeutic agent for skin derma-tomycosis such as a detergent, athlete's foot, disinfectant,

Formulations of the antimicrobial composition include, but are not limited to, an anti-inflammatory agent, a granule, a lotion, liniments, limonades, a handmade powder, a syrup, a syrups, an ointment, Extracts, elixirs, ointments, and should not be construed as limiting the scope of its rights.

The antimicrobial composition of the present invention may further comprise a physiologically acceptable carrier according to the preparation and the method of use, and the content of the essential oil in the antimicrobial composition is preferably 1 to 20% by weight. The dosage of the antimicrobial composition is preferably 10 to 50 mg per day, preferably 1 to 3 times, more preferably in accordance with the severity of the disease and the health condition of the patient.

Examples. Preparation of antimicrobial composition

The antimicrobial composition was prepared based on the blending ratio shown in Fig.

Experimental Example 1 Activity inhibiting the growth of fungi and bacteria

The growth inhibitory activity of 1 pseudomonas species and one Escherichia coli was measured when the appropriate concentration of the antimicrobial composition was applied to the leaves, and the results are shown in Table 2 below.

[Table 2]

As shown in Table 2, when the size of the growth inhibition ring is 10 mm or more, it can be judged that the growth inhibitory activity is effective against fungi and bacteria, and both antibiotic activities are excellent when 100 mg and 50 mg are treated.

Experimental Example 2

The antimicrobial composition according to the present invention was dissolved in ethanol to prepare 5% of the antimicrobial composition.

1. Condition: The plant refinement composition was sprayed on one foot for 3 seconds every day (the level of the plant essential oil was treated with 0.1 g), and the progress of the progress of athrobocyte was examined over time.

2. Results

2-1. Athlete's foot

1) Treatment Day 1: Cracks and eczema have disappeared from the crusted epithelial cells or tissues like eczema.

2) Treatment 2 days: The cleavage site slowly bites.

3) Treatment 3 days: The keratin of the athlete's foot area was formed, and the pain in the athlete's foot area disappeared.

4) Treatment 4 days: Formation of keratin was prominent and showed complete healing.

2-2. Athlete's foot is not severe

It was possible to cure athlete's foot by inducing sufficient keratinization even twice a day.

In addition, the antimicrobial composition according to the present invention was found to have no lesions or adverse effects on the skin due to the use of a natural plant essential oil, and thus it was confirmed that it was harmless to the skin.

The present invention relates to a storage container (B) made of antimicrobial lotion prepared using the antibacterial composition according to the present invention. The storage container (B) comprises a body (B10) And a pump insertion hole B21 through which the pump tube B23 can be inserted is formed in the pump insertion hole B21. The pump tube B23, which is a component of the pump, So that the user can easily dispense the lotion provided in the receiving portion B11.

In general, the lotion agent is in the form of a liquid, and the pump is used in various conventional fields to pump the liquid inside by pumping, and a detailed description thereof will be omitted.

When such a storage container B is used, residues are frequently present on the wall surface of the storage section B11 and the pump tube B23 depending on the viscosity of the solvent provided in the storage section B11, There is a risk of loss, and when other kinds of solvents are put into such a container, there is a problem that the solvent can be mixed.

Therefore, the present invention is intended to solve this problem by providing the scavenging means B30.

Further, when pumping is performed using the pump tube B23, the problem that the pump tube B23 does not suck the solvent when the remaining amount of the solvent is small is also solved.

In order to allow the pump tube B23 to easily suck the solvent even when the solvent (meaning lotion agent in the present invention) is short, the bottom surface of the body B10, that is, the receiving portion B11 The shampoo is naturally concentrated toward the center of the body B10 by gravity and the pump tube B23 can easily suck the remaining shampoo. In particular, a sharp portion B231 is formed at the end of the pump tube B23 to facilitate the suction of the solvent.

The scavenging means B30 is provided in the receiving portion B11 to sweep the shampoo on the inner wall surface of the receiving portion B11 and the outer surface of the pump tube B23 For example,

A ring-shaped support ring B31 through which the pump tube B23 can pass is inserted and a first sweeping-down member B34 is provided on the outer periphery of the support ring B31, And a second scavenging member B35 is provided on the inner side of the support ring B31 to closely contact the outer surface of the pump tube B23.

At this time, it is preferable that the support ring B31 is made of a material such as silicone, plastic or the like that is small in weight so that buoyancy can be formed.

The first and second scraping-down members B34 and B35 are made of rubber or silicone and have elasticity. The inner wall surface of the body B10 and the outer surface When it comes close and descends, it is made to be able to sweep away the buried shampoo.

Further, since the support ring B31 is made of a material forming buoyancy, the supporting ring B31 can float on the shampoo which is filled in the receiving portion B11, and when the shampoo is used, the shampoo descends naturally and wipes off the shampoo And the user can arbitrarily sweep the shampoo down by the configuration of the first magnet B31 and the second magnet B32 which will be described later.

A first magnet B31 connected to the support ring B31 is provided at the outer periphery of the support ring B31, that is, at an upper portion of the first scavenging member B34, And the second magnet B32 is magnetically coupled to the outer surface of the body B10.

Generally, the body B10 is processed through blow molding. Even if the body B10 is positioned between the first magnet B31 and the second magnet B32, the first magnet B31 and the second magnet B31 The support ring B31 inside the body B10 can be attached to the second magnet B32 by the second magnet B32 and the second magnet B32 can be attached to each other by the magnetism, So that the shampoo on the inner wall surface of the accommodating portion B11 and the outer surface of the pump tube B23 can be lowered downward.

In order to solve this problem, the present invention is characterized in that the metallic member B36 is attached to the end of the lid B20, and the metallic member B36 is attached to the end of the lid B20, The second magnet B32 can be magnetically attached to the metal member B36 and can be attached to the lid B20 by raising the scavenging means B30.

Further, in order to ensure convenience in operating the scraping-down means B30, the scraping-down means B30 must be able to move downward. When the scraping-down means B30 is attached to the lid B20, In order to be able to idle,

The body B10 includes an outer wall portion B112 and an inner wall portion B111 that is smaller in diameter than the receiving portion B11 formed by the outer wall portion B112. A linear guide hole B114 through which the first magnet B31 can be inserted is provided.

The first magnet B31 can be drawn into the guide hole B114 and linearly moved down along the guide hole B114 when the scavenging means B30 descends, (When the first magnet B31 is attached to the metal member B36), when the sweeping-down means B30 is located in the space (the rotation inducing portion B113) between the rotation guide portion B113 and the outer wall portion B112 ) The sweep down unit B30 rotates together with the rotation of the lid B20 so that the user can easily remove the sweep down unit B30.

In addition, the support ring B31, the first scavenging member B34 and the second scavenging member B35 are ring-shaped, and the first magnet B31 is provided on both sides of the support ring B31 It is preferable that they are provided so as to correspond to each other.

While the present invention has been described with reference to the accompanying drawings, it is to be understood that the present invention has been described with reference to the antibacterial composition comprising plant essential oil having a specific shape, structure and composition, and a storage container for storing the antiseptic lotion preparation It will be understood by those skilled in the art that various changes, substitutions and substitutions are possible, and that these modifications, alterations, and substitutions are intended to be included within the scope of the present invention.

C: Antibacterial lotion B: Storage container
B10: Body B20: Lid
B30: Sweeping means

Claims (4)

Purified water;
Pure soap containing coconut oil, potassium hydroxide, castor oil, olive oil and sugar;
Plant extracts including rosin, gold extract, rosemary extract, magnolia extract, menthol;
Antimicrobial essential oils containing cetronella, tea tree oil, mayo oil, lavender oil, pine oil, wintergreen oil, benzoin oil, fenugreek oil, cinnamon oil, lemon oil, fennel oil, peppermint oil, grapefruit oil, rosemary oil and eucalyptus oil;
, ≪ / RTI >
When the total weight of the antimicrobial composition is 100 parts by weight,
The purified water consisted of 52.48 parts by weight,
The net soap
11.06 parts by weight of coconut oil, 3.69 parts by weight of potassium hydroxide, 2.57 parts by weight of castor oil, 1.80 parts by weight of olive oil, and 1.54 parts by weight of sugar,
The plant extract additive
0.10 part by weight of rosin, 0.21 part by weight of gold extract, rosemary extract, magnolia extract and menthol,
The antimicrobial essential oil
0.03 part by weight of lignan oil, 0.03 part by weight of lavender oil, 0.03 part by weight of lavender oil, 0.01 part by weight of wintergreen oil, 0.01 part by weight of benzoin oil, 0.01 part by weight of peppermint oil, 0.08 part by weight of cetronella, 1.54 parts by weight of tea tree oil, 5.14 parts by weight of cinnamon oil, 2.57 parts by weight of lemon oil, 0.26 parts by weight of fennel oil, 5.14 parts by weight of peppermint oil, 7.20 parts by weight of grapefruit oil, 0.26 part by weight of rosemary oil and 3.60 parts by weight of eucalyptus oil. delete delete delete

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