KR101965395B1 - Electrospinning apparatus for making a fine line - Google Patents

Abstract

The present invention discloses an electrospinning apparatus for manufacturing a fine line. The apparatus comprises: a solution supply unit for supplying a solution in which a polymer material is dissolved in a fixed amount; a high-voltage supply unit for charging the solution by applying a high voltage thereto; a spinning nozzle unit having at least one hollow tube needle for receiving the solution from the solution supply unit and discharging the solution in a filament form; a conductive member disposed in the spinning nozzle unit, wherein a high voltage is applied to stabilize a conical tailor cone generated from the charged solution and straightly focus a jet of the charged filaments produced at a tail portion of the tailor cone; and an accumulation unit disposed below the spinning nozzle unit and collecting charged filaments.

Description

TECHNICAL FIELD [0001] The present invention relates to an electrospinning apparatus for making fine lines,

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an electrospinning apparatus for fine line production, and more particularly, to an electrospinning apparatus for manufacturing fine wires having a structure capable of controlling the directionality of charged filaments to produce fine lines in a uniform pattern.

Generally, the electrospinning method is a method in which an electric field is formed by applying a (+) DC high voltage of several thousands to several tens of thousands of volts to a polymer solution and connecting a ground or a negative voltage to an integrated collector receiving the charged filament To produce nanofibers. At this time, the charged droplets discharged through the nozzles in a small amount are elongated in the longitudinal direction due to the electric force, and are made of fine fibers having a size of nanometer (nm) to micrometer (탆).

The microfibers produced by the electrospinning process are laminated on the integrated plate and laminated to form a microporous membrane or coated on a predetermined substrate with a thin film. In addition, the process of forming fine lines can be applied to the fabrication of linearly structured circuits.

Charged filaments that form nanofibers in an electrospinning process are made from a charged solution discharged from a hollow tube needle (nozzle) under a high voltage, or from a solution coated thinly on a roll or wire to which a high voltage is applied.

In the case of an electrospinning process using a nozzle, when a charged filament is formed from a droplet discharged from a nozzle, if an electric force larger than the surface tension of the solution is applied, the droplet of the charged solution discharged from the nozzle becomes a conical shape And the conical projection portion is drawn in the longitudinal direction toward the accumulating plate to form the charged filament. At this time, the conical shape formed at the tip of the nozzle is referred to as a taylor cone, and the filament drawn in the longitudinal direction is referred to as a jet. The jets made from the Taylor cone protrusions are made of nanofibers while undergoing a whipping mode and a solvent volatilization process from a higher point at higher electrical power.

The above-mentioned cone-shaped Taylor cone shows an unstable state at the nozzle end as the high voltage intensity becomes stronger and the solvent volatility becomes stronger. If the Taylor cone is unstable, the charged filament jet formed from the Taylor cone becomes unstable because it can not maintain the directionality. If the Taylor cone is unstable at the nozzle end, there is a problem that the lower integrated plate is not uniformly integrated at the same position. In addition, it is difficult to repeatedly and uniformly produce fine lines on a substrate, making it difficult to produce a web having the same shape or size.

In addition, when the core shell structure is manufactured using the coaxial double nozzle, if the tail cone formed at the nozzle tip is unstable, it is difficult to form a cone with a uniform shape because the cone is not formed properly.

If the surrounding radiation environment is asymmetric during the electrospinning process, the charged filament is affected by the position of the nozzle, so that a uniform pattern can not be formed on the substrate.

Patent Document 1 and Patent Document 2 disclose a method of forming a pattern structure by electrospinning. Near-field electrospinning is used to manufacture fine lines by setting the distance between the nozzle and the integrated plate to 5 mm or less. However, the conventional near field electrospinning apparatus has a limitation in manufacturing fine lines with a high viscosity solution. That is, in the case of a high-viscosity solution, the voltage intensity must be increased to fabricate fine lines, but the state of the tail cone formed at the tip of the nozzle becomes unstable at high high voltage intensities.

On the other hand, in the bio-field, a multi-layered structure of a 3D structure is manufactured by combining a melt spinning process and an electrospinning process in the process of making a lattice structure using a medical biopolymer. However, when a nanofiber layer is formed by an electrospinning process on a structure layer composed of a polymer fiber having a large diameter by melt spinning, it is difficult to form a thick layer due to the charge remaining on the polymer structure. The scaffolds used as cell culture supports should be made of a three-dimensional web. However, if the thickness of the scaffold is constant during the manufacturing process, the charge of the charged filament accumulates on the web surface and is accumulated in the same area due to the repulsion of the filament having the same charge. It is difficult to make a thick web.

That is, in the conventional electrospinning device, the integrated portion is simply grounded or connected to a high-voltage supply device having a polarity opposite to that of the charged solution, thereby integrating the nanofibers. However, such a method is not suitable as a method of producing a thick web having a high degree of arrangement of nanofibers. As the nanofibers are integrated in the integrated portion, the nanofiber arrangement becomes worse and the surface charge of the web is maintained, so that the subsequent filaments having the same charge are repelled and are not integrated at the designated positions. As a result, there is a problem that a thick web can not be manufactured due to the charge formed on the integrated portion.

On the other hand, when the high voltage intensity is increased, the syringe mounted on the solution transferring apparatus is broken down, and a high voltage electric field is formed around the pump, so that the control circuit of the solution transferring apparatus can not be controlled due to an electrical shock due to an instantaneous leak . This problem frequently occurs as the high voltage intensity is increased.

Patent Document 1: Korean Patent Publication No. 10-1688817 Patent Document 2: Korean Patent Publication No. 10-1610782

It is an object of the present invention to provide an electrospinning device for fine line manufacturing which is capable of uniformly fabricating fine line patterns by uniformly electrospinning a polymer solution.

It is another object of the present invention to provide an electrospinning method for fine line fabrication which can stably maintain a swing of a charged solution formed on a tip of a nozzle during electrospinning to maintain a linear state of the charged filament with respect to the integrated part, Device.

It is still another object of the present invention to provide an electrospinning apparatus for fine line production, which can manufacture thick webs by controlling the directionality of charged filaments and repeatedly and uniformly focusing charged filaments at specific positions of the integrated portion.

It is another object of the present invention to provide an electrospinning device for manufacturing fine lines having a structure capable of blocking leakage high voltage of a syringe.

According to an aspect of the present invention, there is provided a polymer electrolyte fuel cell comprising: a solution supply unit for supplying a solution in which a polymer material is dissolved; A high voltage supplier for charging the solution by applying a high voltage thereto; A spinneret portion having at least one hollow tube needle for receiving a solution from the solution supply portion and discharging the solution in a filament form; A conductive member disposed in the spinneret portion to apply a high voltage to stabilize the conical tailor cone generated from the charged solution and to focus the jet of the charged filament generated at the end of the tail cone in a straight line with respect to the substrate; And an accumulation unit disposed below the spinning nozzle unit and collecting charged filaments.

Preferably, the conductive member is a metal plate or a metal tube disposed at a lower portion of the spinning nozzle portion, and the hollow tube needle is disposed at the center of the conductive member.

Wherein the metal plate is composed of a metal circular plate having a diameter of 5 mm to 50 mm and a thickness of 1 mm to 5 mm and the metal tube is composed of a metal circular tube having an inner diameter of 3 mm to 10 mm and an outer diameter of 4 mm to 15 mm, May be located 1 mm to 20 mm above the lower end of the spinning nozzle unit and the lower end of the metal pipe may be located 1 mm to 5 mm above the lower end of the spinning nozzle unit.

And an auxiliary cap disposed to surround the hollow needle.

And a metal spring for electrically connecting the hollow tube needle and the metal disk within the auxiliary cap.

The conductive member may include a plurality of guide pins disposed around the hollow needle.

Preferably, the guide pins have a diameter of 1 mm to 10 mm and are disposed at intervals of 72 to 180 degrees around the hollow needle.

And a robot driving unit that reciprocates in a section defined in the horizontal and vertical directions to control the integrated area of the charged filament.

The accumulating portion is formed of a drum type rotating body or a flat plate and is grounded or connected to a negative electrode to generate a charge having a polarity opposite to the polarity of the solution to guide the direction of accumulation of the charged filament to a region having a charge of opposite polarity And a charge discharging part for neutralizing the charge of the charged filament.

The charge discharger may include a plurality of needles having a diameter of 0.5 mm to 8 mm or a rod having a pointed end having an electrode needle, and the electrode needles may be installed at intervals of 0.1 mm to 20 mm from the surface of the accumulating portion.

It is preferable that the high voltage providing unit applies a high voltage of (+) 1 kV to (+) 50 kV to the solution and applies a high voltage of (-) 1 kV to (-) 50 kV to the charge discharging unit.

The solution supply unit includes a motor unit, a screw connected to the shaft of the motor unit, a syringe having a plunger therein, a pusher coupled to the screw to push the plunger of the syringe, and a high voltage And a nozzle holder portion to which a high voltage is applied by the high voltage applying means.

According to the present invention, an electrospinning apparatus for fine line production has the following effects.

First, by disposing a conductive member including a guide pin and a metal disk around the needle body of the nozzle, a tailor cone formed at the nozzle end is formed in a stable state, and the charged filament formed therefrom is maintained in a certain direction So that a uniform pattern composed of fine lines can be formed on the substrate.

Secondly, by forming a stable tail cone at the nozzle end, a structure having a double structure of core shell can be easily manufactured.

Third, since the charge discharge electrode having an acicular structure that discharges the charge of the polarity opposite to the polarity of the charged filament to the accumulation portion is formed, the fine lines are repeatedly and uniformly integrated so that a thick web having a thickness of 1 mm or more can be manufactured.

Fourth, the solution transfer apparatus having the nozzle holder integrally formed with the syringe can solve the problem such as electrical short of the control unit by breaking the high voltage leaked from the syringe.

BRIEF DESCRIPTION OF THE DRAWINGS The accompanying drawings, which are incorporated in and constitute a part of the specification, illustrate preferred embodiments of the invention and, together with the description of the invention given below, serve to further the understanding of the technical idea of the invention. And should not be construed as limiting.
FIG. 1 is a front view showing a configuration of an electrospinning apparatus for manufacturing fine lines according to a preferred embodiment of the present invention.
FIG. 2 is a side view showing the structure of the solution supply part and the spinning nozzle part in FIG.
3 is a perspective view of FIG.
Fig. 4 is a perspective view showing a modification of Fig. 3. Fig.
5 is a cross-sectional view showing a main configuration of the portion A in Fig.
Fig. 6 is a sectional view showing the configuration of a syringe and a spinning nozzle unit having a syringe cover in Fig. 2. Fig.
Fig. 7 is a view showing the arrangement structure of the conductive member in Fig. 1. Fig.
FIG. 8 is a cross-sectional view illustrating a structure including multiple nozzles in an electrospinning apparatus for fine line manufacturing according to a preferred embodiment of the present invention.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. Prior to this, terms and words used in the present specification and claims should not be construed as limited to ordinary or dictionary terms, and the inventor should appropriately interpret the concepts of the terms appropriately It should be interpreted in accordance with the meaning and concept consistent with the technical idea of the present invention based on the principle that it can be defined. Therefore, the embodiments described in this specification and the configurations shown in the drawings are merely the most preferred embodiments of the present invention and do not represent all the technical ideas of the present invention. Therefore, It is to be understood that equivalents and modifications are possible.

FIG. 1 is a front view showing the configuration of an electrospinning device for microneutilizing according to a preferred embodiment of the present invention, FIG. 2 is a side view showing the structure of a solution supply part and a spinning nozzle part in FIG. 1, Fig. 4 is a perspective view showing a modified example of Fig. 2, Fig. 5 is a sectional view showing the inner configuration of the spinning nozzle unit in Fig. 2, and Fig. 6 is a sectional view showing the configuration of a syringe and spinning nozzle unit having a syringe cover in Fig. to be.

1 to 6, an electrospinning device for manufacturing a fine wire according to a preferred embodiment of the present invention includes a solution supply part for supplying a raw polymer solution, a high voltage providing part 110 for applying a high voltage to the solution, A collecting part 140 for collecting the charged filaments, a collecting part 140 for collecting charged filaments, a collecting part for collecting collected charged filaments, And a charge discharging part 170 for leading the charged filament to a region having a charge of opposite polarity and neutralizing the charge of the charged filament.

The solution supply part supplies a solution in which the polymer material is dissolved. The solution supply unit includes a syringe (108 in FIG. 2) and a solution transfer pump 100 for transferring the solution stored in the syringe 108 toward the spinning nozzle unit 120.

The syringe 108 is preferably provided with a container cylinder having an internal volume of 100 to 500 ml. Alternatively, a storage tank having an internal capacity of 500 ml to 5,000 ml may be employed. A plunger 107 corresponding to the plunger is inserted into the container barrel of the syringe 108. In the case of a storage tank without the plunger 107, the solution may be transferred to the air pressure. The syringe 108 is preferably made of an insulating material such as polypropylene (PP), polyethylene (PE), polyetheretherketone (PEEK), nylon, acetal, glass and the like having excellent withstand voltage. If the barrel is a thin insulator, it may be destroyed at a high high voltage during the electrospinning process, or electricity of the charged solution may be discharged outside the syringe 108 on the connection portion, so that a cover made of an insulating material is used together with the outside of the barrel .

The polymer solution to be injected into the syringe 108 may be polyvinylidene fluoride (PVDF), poly (acrylonitrile), polyvinyl alcohol (PVA) , Poly (imide), polyethylene oxide (PEO), polylactic-co-glycolic acid (PLGA), polylactic acid (PLA polylactic acid), polylactic acid (PLLA), polyglycolic acid (PGA), and polycaprolactone (PCL) (polycarpro lactone). Or a polymer solution containing conductive particles, or the like can be applied.

When a double-layer structure of a core-shell structure is prepared, the above-mentioned polymer solution is employed as the shell part solution, and the core part solution can employ functional materials such as oil. At this time, the functional material may be a conductive material including a drug, silver (Ag) or carbon-based particles, an antibacterial deodorant, a fragrance microcapsule, an electromagnetic wave shielding material, an ultraviolet ray hardening material, oil and the like.

The solution stored in the syringe 108 is transferred to the spinning nozzle unit 120 through the solution transfer pump 100. The solution transfer pump 100 is connected to a motor unit 103 composed of a stepping motor or a servo motor so as to keep the transfer amount of the solution constant. As the solution transfer pump 100, a conventional quantitative transfer pump or a peristaltic pump may be used.

The motor section 103 is attached to the motor mounting block 104 and transmits power to the screw 105 through a predetermined coupling. At this time, the coupling is disposed between the motor shaft and the screw 105 so that the high-voltage leakage through the screw 105 is interrupted. As the motor unit 103, a stepping motor or a servo motor may be used, and it is more preferable that a stepping motor is employed for fine movement. The encoder 102 is attached to the rear surface of the motor unit 103 to sense the rotation of the motor. When the rotation of the screw 105 is stopped for 1 to 2 seconds, for example, the encoder 102 senses the rotation of the motor unit 103 to stop the operation of the motor unit 103, To prevent overheating.

The pusher block 106 attached to the screw 105 pushes the plunger 107 of the syringe 108 to urge the solution in the barrel of the syringe 108 into the spinneret 108, (120). At this time, the discharge amount of the solution is set at 0.05 / / min to 500 / / min per nozzle hole. A preferable amount of the solution for discharging nanofibers is 0.2 μl / min to 50 μl / min. Here, the lead of the screw 105 is 0.5 mm to 2 mm. Preferably 1 mm. It is preferable that the moving speed of the pusher block 106 in accordance with the rotation of the screw 105 has a minimum speed of 1 탆 / hour to 100 탆 / hour and a maximum speed of 1 cm / min to 20 cm / min. The pusher may be installed and moved to the linear block instead of the guide rod.

The syringe holder 109 for fixing the syringe 108 is preferably made of an insulating material such as acetal or polyethyl ethyletherketone (PEEK) so as to block the current flowing to the outside of the syringe 108. The holder for fixing the syringe 108 may be configured to seat several to several tens of syringes 108 as needed.

The high voltage supplier 110 applies a high voltage to the solution to charge the solution. The high voltage supplying unit 110 is a device for supplying a DC power source, and the DC power source is supplied to the solution through contact with the spinneret nozzle unit 120. The DC voltage applied to the spinning nozzle unit 120 is 0.01 kV / cm to 10 kV / cm between the nozzle and the accumulation unit 140. The preferred voltage intensity is 1 kV to 50 kV at a distance of 1 cm to 30 cm between the nozzle (hollow tube needle 122) and the integrated portion 140. In the case of near-field electrospinning, the distance is preferably 0.1 cm to 2 cm, and the applied voltage is preferably 0.1 kV / cm to 1.5 kV / cm. The high voltage intensity can be appropriately set from the charged solution discharged through the nozzle according to the production of fine lines or nanofibers, the kind of the polymer, the viscosity of the polymer, the characteristics of the nozzle, and the shape of the disk formed in the nozzle.

The high voltage generated in the high voltage supplying unit 110 is supplied to the nozzle through a predetermined metal pipe installed inside the spinning nozzle unit 120. The spinning nozzle unit 120 includes a nozzle holder portion 101 (see FIG. 3) to which the hollow tube needle 122 mounted on the syringe 108 can be seated, and a high voltage cable portion 130 connected to the high voltage cable 190, And a conductive member 121 coupled to the nozzle cap (123 in FIG. 5) to which a high voltage is applied. The metal tube allows a high voltage to be applied to the solution through contact with the nozzle. The material of the metal tube is preferably stainless steel (SUS), copper or brass. In the case of a corrosive solution, a metal tube of SUS material is more suitable. The nozzle holder portion 101 has a nozzle plate (124 in Fig. 5). The nozzle plate 124 is preferably made of an insulating material made of PEEK, acetal, or nylon. A more preferable material is PEEK having excellent insulating properties. The mounting position of the nozzle plate at the lower end of the holder of the syringe 108 in the solution transfer pump 100 may vary depending on the size of the syringe 108.

The spinning nozzle unit 120 has at least one hollow tube needle 122 for receiving a solution from the solution transfer pump 100 and discharging the solution in a filament form. Specifically, the hollow tube needle 122 preferably has an inner diameter of 0.01 mm to 2 mm, an outer diameter of 0.02 mm to 3 mm, and a length of 2 mm to 100 mm.

The spinning nozzle unit 120 includes a nozzle holder 101 for applying a high voltage to hold the hollow tube needle 122, a nozzle cap 123 on which the hollow tube needle 122 is seated, a high voltage cable 190, Voltage applying means for applying a high voltage to the nozzle, and a conductive member 121 connected to the high-voltage applying means.

In addition, a syringe housing 151 may be provided at an upper end of the spinning nozzle unit 120. At this time, the high voltage application nozzle holder unit 101 is preferably integrated with the syringe housing 151 to block high voltage leakage from the syringe 108.

The conductive member 121 is disposed in a one-to-one correspondence with the hollow tube needle 122 provided in the spinning nozzle unit 120, and stabilizes the conical tail cone generated from the charged solution, and the charged filament A high voltage is applied so as to converge the jet in a straight line.

The conductive member 121 is a metal plate (121a in FIG. 3) which is a metal plate disposed at a lower portion of the spinning nozzle unit 120 so that the hollow tube needle 122 is aligned with the center, An auxiliary cap 121c disposed to surround the hollow tube needle 122, a metal circular tube 121d (FIG. 4), or a combination of at least two of them.

When the metal plate 121a and the auxiliary cap 121c are combined as the conductive member 121, as shown in FIG. 5, the metal plate 121a is attached to the inside of the lower portion of the auxiliary cap 121c so that the rim is not exposed . The size of the metal disk 121a is preferably 5 mm to 50 mm in diameter and 1 mm to 5 mm in thickness. It is preferable that the position of the metal disc 121a is 1 mm to 20 mm from the tip of the nozzle from which the solution is discharged to the top. A more preferable position is 2 mm to 10 mm.

The metal disk 121a is made of any one of SUS metal, aluminum, and brass.

Preferably, a plurality of guide pins 121b are provided around the metal disc 121a at regular intervals to control the directionality of the charged filament. The guide pin 121b is used to additionally adjust the directionality of the charged filament.

One to five guide pins 121b may be disposed around the metal disc 121a at an interval of 72 degrees to 180 degrees. The protruding length of the guide pin 121b is adjusted within a range of 5 cm or less from the periphery of the metal disc 121a. The guide pin 121b preferably has a diameter of 1 mm to 10 mm and is made of SUS metal. At this time, the guide pin 121b may be formed in the auxiliary cap 121c instead of the metal disc 121a. If the guide pins 121b are provided at four positions around the metal disk 121a or the auxiliary cap 121c at 90 degree intervals, only one of the guide pins 121b may be projected without protruding three locations as needed to control the directionality of the charged filament . According to a modification of the present invention, the guide pin 121b may be replaced by a plate-shaped guide in the form of a strip. In the case of a strip-shaped plate-shaped guide, the width of the plate is preferably from 2 mm to 10 mm, and the thickness is preferably from 0.1 mm to 5 mm. The material of the plate is preferably metal-based SUS.

When a high voltage is applied to the nozzle, the metal disk 121a and the guide pin 121b of the auxiliary cap 121c are both applied with a high voltage so that the balance of the Taylor cone and the directionality of the charged filament are controlled.

The auxiliary cap 121c may be made of any one of metal, brass non-metal, Teflon, PEEK, and acetal. When the auxiliary cap 121c is made of an insulating material, a high voltage is applied to the metal disk 121a by installing a metal spring 124 from the nozzle to the disk in the auxiliary cap 121c.

On the other hand, in the case of the individual nozzles configured without the nozzle plate, the metal disc 121a including the guide pin 121b is directly formed on the nozzle body. 7A shows a structure of a nozzle in which a metal disc 121a including a guide pin 121b is attached to a needle body of a single hollow tube needle 122. As shown in Fig. 7B shows a coaxial double nozzle in which a metal disc 121a including a guide pin 121b is attached to the body of the hollow tube needle 122. As shown in FIG. 7 (c) shows a coaxial double nozzle in which the metal disc 121a is mounted on the auxiliary cap 121c. When the auxiliary cap 121c is made of metal, the balance of the charged filament can be maintained at the nozzle end with only the auxiliary cap 121c without the metal disc 121a. In the case of all the individual nozzles described above, high voltage application of the metal disk 121a is performed through the body of the hollow tube needle 122. [ The guide pin 121b is used as an auxiliary means for controlling the directionality of the charged filament as described above.

The metal circular tube 121d is positioned such that the hollow tube needle 122 coupled to the syringe 108 is positioned centrally and is positioned higher than the hollow tube needle 122 such that the hollow tube needle 122 is positioned substantially downward Respectively. The metal circular tube 121d preferably has an inner diameter of 3 mm to 10 mm, an outer diameter of 4 mm to 15 mm, and a lower end position of 1 mm to 5 mm higher than the needle tip.

The collecting unit 140 is disposed below the spinning nozzle unit 120 to collect charged filaments. The accumulating unit 140 may be constituted by a drum type rotary body 160, a flat plate, a conveyor, a roll having a diameter of 5 mm to 50 mm, a conveyor having a plurality of rods having an outer diameter of 1 mm to 5 mm , Or a combination thereof. The distance between the rolls and the rods can be adjusted to a large gap as needed within the range that the surface is not in contact. In the case of a continuous process, a roller accumulating portion or a plurality of rod collecting portions are preferable. The integrated portion 140 is connected to ground or a negative (-) DC voltage. When the ground is connected to the accumulation unit 140, an electric field is formed between the nozzle unit and the accumulation unit 140 to create an electrospinning environment.

The charge discharger 170 is composed of a plurality of needle needles. When a (+) direct current high voltage is applied to the solution, the drum rotating body or flat plate as the accumulating part 140 is put in a grounded or no-grounded state, and (-) direct current is connected to the electrode needle. When the charge discharging unit 170 is formed with respect to the drum-type rotating body 160, a plastic insulator may be used as the material of the drum rotating body 160.

The charge discharging unit 170 is installed at an interval of 0.1 mm to 20 mm from the surface of the accumulating unit 140. An electrode needle generating positive (-) charges induces the accumulation direction of the charged filament to a region having a charge of opposite polarity, and then neutralizes the charge of the charged filament. In addition, when the nanofibers are accumulated in the accumulation unit 140 during spinning, a thick web can be produced by neutralizing the (+) charges remaining on the surface. The diameter of the electrode needle constituting the charge discharging portion 170 is 0.5 to 8 mm. A preferred electrode needle is a rod having a diameter of 2 mm to 5 mm with one end pointed.

The charge discharging unit 170 is integrated with a plurality of electrode needles as much as the width or length of the accumulating unit 140. The distance between the electrode needles is preferably 0.5 mm to 50 mm. High voltage polarity is applied when a positive voltage is applied to a solution, and when a positive voltage is applied to a solution, a positive voltage is applied to a solution. The high-voltage intensity is in the range of 1 kV to 50 kV, as opposed to the applied polarity of the solution.

It is preferable that the charge discharging unit 170 is repeatedly driven along the width or longitudinal direction of the accumulating unit 140 to produce a uniform and uniform thickness web on the drum type rotating body 160 or the flat accumulating unit 140 Do. With this configuration, a thick web having a thickness of 1 mm or more can be manufactured.

The robot driving units 130 and 131 repeatedly reciprocate in the horizontal or vertical direction of the accumulating unit 140 so that the fine lines radiated to the accumulating unit 140 having a predetermined size can be uniformly accumulated. The angle adjusting unit 180 may be provided at the front end of the robot driving units 130 and 131 to adjust the angle of radiation to realize vertical or horizontal radiation.

The control unit 111 includes a display screen, numeric buttons, and function input buttons. The display screen displays the start and end points of the X and Y axes, the robot driving speed, the rotating speed, the discharge progress amount during driving of the solution supply unit, the total discharge amount, the flow rate, the diameter of the syringe, . The buttons for inputting numbers and functions can input the number of X axis lines and the movement distance between Y axis steps of the robot driving units 130 and 131. The buttons for turning on and off the motors of the solution supply unit and the flow rate control buttons, A jog button for quickly driving the motor at a speed, and a previous stage moving button. When the flow control button is pressed, it is possible to directly input the total discharge amount of the solution, the flow control unit selection, the flow control amount, the syringe selection by the manufacturer and the syringe capacity of the selected manufacturer or the inner diameter of the syringe, (nl) / minute or microliter (占)) / minute or milliliter (mℓ) / hour (hr), and the encoder 102 is configured to be able to select whether to use the function of the encoder 102, Function If a problem occurs, the function can be disabled and the motor can be continuously driven.

The electrospinning apparatus according to the present invention may include a high voltage generating apparatus capable of applying (-) polarity to the accumulating unit 140 instead of ground. In addition, an imaging system capable of monitoring the radiation state of the Taylor cone formed from the charged solution at the nozzle end in real time and storing it as a moving image or an image may be included.

Fig. 8 shows the configuration of multiple nozzles including the metal disc 121a. In the case of multiple nozzles, a body 126 connected from a syringe 108 to a solution transfer line (not shown), and a plurality of capillary hollow needle 122 integrally arranged along the length of the body do.

An electrode needle or an electrode rod configured to be applied to a voltage applying plate to which a high voltage can be applied and an electrode to which a voltage is applied in the vicinity of a plurality of nozzles to which the solution transferred to the body portion 126 flows, A plurality of adapter mounts communicating with the space, and an auxiliary cap 121c having a metal disk connected to the adapter mount are formed at regular intervals. The length of the electrode needle or the electrode rod configured in the voltage applying plate is adjusted so that a high voltage can be directly applied to the solution in the vicinity of the nozzle or in contact with the plurality of nozzles. At this time, the high voltage application is configured so that the metal SUS-based solution injection port is directly contacted to the high voltage application plate, and the high voltage power supply is configured to be connected to the solution injection port. The voltage applying plate is preferably made of SUS metal resistant to corrosiveness.

The body portion 126 of the multiple nozzles is made of a fluoropolymer such as PEEK, acetal, or Teflon, a polypropylene-based, nylon-based, or polyester-based material. The adapter mount 404 is preferably a PEEK material. The adapter mount may have a luer lock structure with a double-threaded screw. The auxiliary cap 121c is provided with a metal disc 121a at its lower portion and a spring 124 provided therein to apply a high voltage of the same polarity from the nozzle to the metal disc 121a. The auxiliary cap 121c is preferably made of an insulating material such as Teflon, PEEK resin or acetal resin. In the case of metal, formation of an electric field between adjacent auxiliary caps 121c is not desirable because the applied high voltage intensity must be increased during the spinning process.

The distance between the nozzles in the multiple nozzles is preferably 10 mm to 100 mm. As the distance between the nozzles becomes narrower, the repulsive force of the charged filament becomes larger, so that the linearity of the filament becomes lower and the radiation becomes unstable.

With the electrospinning apparatus of the present invention, the tail cone formed at the tip of the nozzle maintains a stable state while forming a jet in the longitudinal direction. Taylor cones and jets maintain a steady state without bias in either direction from the tip of the nozzle, even at high high voltage environments above 10 kV. The jet of the charged filament may be formed on a substrate such as a metal plate, a film, a fiber fabric, a fabric, a nonwoven fabric, a paper, a metal plate, a glass plate, or a ceramic plate. In addition, the jet is made from micro- to nano-sized microfibers while a long elongated jet at a higher high voltage undergoes significant fluctuations and solvent volatilization from a specific point. The prepared microfibers are piled up on a grounded integrated plate to form a membrane.

The electrospinning device for the production of fine wires of the present invention is used for manufacturing nanofiber webs, microporous membranes, hollow nanofibers, scaffolds for cell culturing, and fine line construction circuits.

Example  One

In Example 1, the used electrospinning apparatus shown in Fig. 1 was used.

The spinning solution is a clear solution prepared by mixing PVDF [(poly) vinylidenefluoride (Kynar 2801, manufactured by Arkema) with acetone: dimethylacetamide (DMAc) in a solvent mixture of 17: 3 by weight. The spinning solution is placed in a syringe 108 having a capacity of 10 ml in which the plunger 107 is mounted and the solution outlet portion is made of a luer lock structure and a hollow needle 122 is placed at the outlet of the syringe 108 And then attached to a constant-rate feed pump. The metal nozzle connected to the syringe 108 is in contact with the high voltage application metal tube formed in the nozzle plate of the quantitative transfer pump and the auxiliary cap 121c having the metal disk 121a is formed in the nozzle plate. The metal disc 121a of the auxiliary cap 121c is located 2 mm above the nozzle end. The guide pin 121b is used without being protruded inside the metal disc 121a.

The electrospinning was carried out by driving the motor with high voltage applied. The high voltage intensity was set at 15 kV, the solution discharge rate was 10 / / min, and the nozzle was 27 G (inner diameter 0.2 mm, needle length 13 mm). The stacking unit 140 uses a flat SUS metal plate. The distance between the nozzle tip and the SUS plate is 13 mm.

An optical microscope (Vinity, model: UM08) was used to photograph the line width and line distance of the linear pattern. As a result, a line having a micrometer line width on the integrated plate can be manufactured using the nozzle having the hollow plate needle 122 formed of the original plate. At this time, the line width was 45 탆 to 50 탆, and the line-to-line distance was 380 탆 to 400 탆. This embodiment is an example for showing a technique of repetitively drawing a line to produce a linear pattern, and it is also possible to produce nano-scale fine lines according to the viscosity and discharge amount of the solution and the nozzle diameter.

By using a nozzle having a disk on the needle even in a high-voltage environment where the distance between the nozzle tip and the accumulating part 140 is 10 mm or more in the course of finely manufacturing the charged filament from a solution having a high viscosity, Stable discharge can be achieved without the shaking of Taylor cone and jet, so it was possible to fabricate line pattern by electrospinning process. The present invention shows that a line pattern can be produced by an electrospinning process in a state in which the distance between the nozzle and the integrated plate is increased.

Example  2

The second embodiment stabilizes the directionality of the charged filament discharged to the nozzle and neutralizes the charge on the accumulation unit 140 by providing a charge discharge unit 170 having an opposite polarity to the charge filament with respect to the accumulation unit 140 The web was continuously thickened by focusing the fine lines.

In Example 2, the same solution and spinning apparatus as in Example 1 were used. The accumulating unit 140 uses a plastic drum rotating body made of acetal, which is an insulator. Then, the charge discharging portion 170 was provided at a distance of 2 mm relative to the drum rotating body. The charge discharger 170 is composed of a plurality of electrode needles with a diameter of 0.4 mm, a gap of 2.5 mm, and a width of 10 cm. The high voltage applied to the solution was (+) 14kV, and the high voltage applied to the electrode needle was (-) 14kV. The distance between the stacking units 140 was fixed to 14 cm. The used nozzle was 25 G (0.25 mm) and the discharge amount was 30 / / min. The fine lines were collected on the drum rotating body while the robot equipped with the nozzle part during spinning was repeatedly driven 5 cm in the width direction of the drum rotating body.

As a result, it was confirmed that a web having a thickness of 1 mm or more was manufactured by continuously collecting fine lines on the plastic drum rotating body as the accumulating unit 140. The present embodiment is characterized in that the charge discharging part 170 that discharges the charge of the polarity opposite to the polarity of the charged filament accumulated in the insulating drum rotating body is neutralized with the charge of the charged filament on the drum, Respectively.

Example  3

In Example 3, a coaxial double nozzle (core-shell coaxial nozzle) having an auxiliary cap 121c including a guide pin 121b formed therein was used to emit. Polyethylene oxide (PEO) solution was used for the shell part solution and silver (Ag) solution was used for the core part solution. In the coaxial double nozzle, the inner diameter of the center nozzle was 0.15 mm, the thickness of the shell part was 0.05 mm, the amount of discharge was 25 μl / min of the Ag solution in the core part, 250 μl / min of PEO solution in the shell part, (140) is set to 15 cm. The position of the tip of the nozzle was set 2 mm further down from the bottom of the auxiliary cap. In the state where the charged filament was slightly inclined during spinning, a guiding pin 121b having a diameter of 5 mm on the opposite side was protruded 3 cm to the outside of the auxiliary cap to linearly adjust the position of the charged filament. As a result, it was confirmed that the core shell structure was formed at the tip of the nozzle. Since the solution boundary clearly appears in the core portion and the shell portion of the charged filament, it can be seen that the use of the nozzle in which the metal disk 121a is disposed has a remarkable effect.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not to be limited to the details thereof and that various changes and modifications will be apparent to those skilled in the art. And various modifications and variations are possible within the scope of the appended claims.

100: solution transfer pump 101: nozzle holder part
102: Encoder 103: Motor section
104: Motor mounting block 105: Screw
106: pusher block 107: plunger
108: Syringe 109: Syringe holder
110: high voltage supply unit 120: spinning nozzle unit
121: Conductive member 121a: metal plate
121b: guide pin 121c: auxiliary cap
121d: metal circular tube 122: hollow tube needle
123: nozzle cap 130,131: robot driving part
140: Integrated part 151: Syringe housing
160: Drum type rotation body 170: Charge discharge part
180: Angle adjuster 190: High voltage cable
201: solution storage portion of the nozzle

Claims (12)

A solution supply part for supplying a solution in which the polymer material is dissolved in a fixed amount;
A high voltage supplier for charging the solution by applying a high voltage thereto;
A spinneret portion having at least one hollow tube needle for receiving a solution from the solution supply portion and discharging the solution in a filament form;
The tubular conical tail cone generated from the charged solution is stabilized in a one-to-one correspondence with the at least one hollow tubular needle, and the jet of the charged filament produced at the end of each tail cone is linearly focused A conductive member to which a high voltage is applied; And
And an accumulation unit disposed below the spinning nozzle unit and collecting charged filaments,
The conductive member includes:
A plurality of metal discs disposed at a lower portion of the spinning nozzle unit so that the hollow tube needles are aligned with the center, a plurality of metal discs disposed at regular intervals around the hollow metal tube, And a plurality of guide pins for guiding the microwires. delete The method according to claim 1,
Wherein the metal plate is made of a metal plate having a diameter of 5 mm to 50 mm and a thickness of 1 mm to 5 mm,
And the lower end of the metal disk is located 1 mm to 20 mm above the lower end of the spinning nozzle unit. The method according to claim 1,
And an auxiliary cap disposed to surround the hollow tube needles. 5. The method of claim 4,
And a metal spring for electrically connecting the hollow tube needle to the metal disk in the auxiliary cap. delete The method according to claim 1,
Wherein the guide pins have a diameter of 1 mm to 10 mm and are arranged at an interval of 72 to 180 degrees around the hollow tube needles. The method according to claim 1,
And a robot driving unit for reciprocating the section defined by the horizontal and vertical directions to control the integrated area of the charged filament, The method according to claim 1,
The integrated unit may include a drum type rotating body or a flat plate, and may be grounded or connected to a negative electrode,
And a charge discharging part for generating charges having a polarity opposite to the polarity of the solution to guide the direction of accumulation of the charged filament filaments to a region having a charge of opposite polarity and neutralize the charge of the charged filament Electrospinning device. 10. The method of claim 9,
Wherein the charge discharger comprises a plurality of needle-like needles having a diameter of 0.5 mm to 8 mm, or a rod having a pointed end at one end,
Wherein the electrode needles are installed at intervals of 0.1 mm to 20 mm from the surface of the integrated portion. 10. The method of claim 9,
Wherein the high voltage providing unit applies a high voltage of (+) 1 kV to (+) 50 kV to the solution and applies a high voltage of (-) 1 kV to (-) 50 kV to the charge discharging unit. The apparatus according to claim 1,
A high voltage applying means for applying a high voltage to the needle of the hollow tube; a high voltage applying means for applying a high voltage to the needle of the hollow tube; And a nozzle holder part for applying a high voltage by an application means.

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