KR101947152B1 - 신규한 벤젠설폰아미드 유도체 및 이의 용도 - Google Patents

신규한 벤젠설폰아미드 유도체 및 이의 용도 Download PDF

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Publication number
KR101947152B1
KR101947152B1 KR1020170032080A KR20170032080A KR101947152B1 KR 101947152 B1 KR101947152 B1 KR 101947152B1 KR 1020170032080 A KR1020170032080 A KR 1020170032080A KR 20170032080 A KR20170032080 A KR 20170032080A KR 101947152 B1 KR101947152 B1 KR 101947152B1
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KR
South Korea
Prior art keywords
dimethyl
oxo
pyrazol
benzenesulfonamide
isopropyl
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Application number
KR1020170032080A
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English (en)
Korean (ko)
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KR20170107404A (ko
Inventor
김성훈
한균희
양지선
이철호
김재현
정길수
한정민
김종현
Original Assignee
재단법인 의약바이오컨버젼스연구단
연세대학교 산학협력단
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Publication of KR20170107404A publication Critical patent/KR20170107404A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4152—1,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C07D231/42—Benzene-sulfonamido pyrazoles

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020170032080A 2016-03-15 2017-03-14 신규한 벤젠설폰아미드 유도체 및 이의 용도 KR101947152B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020160030845 2016-03-15
KR20160030845 2016-03-15

Publications (2)

Publication Number Publication Date
KR20170107404A KR20170107404A (ko) 2017-09-25
KR101947152B1 true KR101947152B1 (ko) 2019-02-12

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KR1020170032080A KR101947152B1 (ko) 2016-03-15 2017-03-14 신규한 벤젠설폰아미드 유도체 및 이의 용도

Country Status (2)

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KR (1) KR101947152B1 (fr)
WO (1) WO2017160069A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210089290A (ko) 2020-01-07 2021-07-16 한국과학기술연구원 신규한 1-페닐-1h-피라졸 유도체 및 이의 용도
WO2023002011A1 (fr) * 2021-07-23 2023-01-26 Institut National De La Sante Et De La Recherche Medicale (Inserm) Inhibiteurs de pompe d'efflux de bactéries à gram négatif

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI823890B (zh) 2018-01-10 2023-12-01 美商克拉治療有限責任公司 包含苯基磺醯胺之醫藥組合物及其治療應用
JP7491510B2 (ja) 2018-04-26 2024-05-28 メディシナル バイオコンバージェンス リサーチ センター ｍＴＯＲ阻害剤としての新規化合物及びその用途
AU2020310190A1 (en) * 2019-07-11 2022-02-24 Cura Therapeutics, Llc Phenyl compounds and pharmaceutical compositions thereof, and their therapeutic applications

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040024008A1 (en) 2002-07-29 2004-02-05 Wyeth Dihydrodipyrazolopyridinylbenzamide and -sulfonamide inhibitors of B7-1

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101210273B1 (ko) * 2008-12-18 2012-12-10 한국전자통신연구원 온칩 네트워크 토폴로지 합성 방법
WO2011100840A1 (fr) * 2010-02-17 2011-08-25 UNIVERSITé LAVAL 2-imidazolidones substitues et analogues
CA2844783C (fr) * 2011-08-16 2019-10-29 Universite Laval 2-imidazolidinones et 2-imidazolones substituees et leur utilisation dans le traitement du cancer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040024008A1 (en) 2002-07-29 2004-02-05 Wyeth Dihydrodipyrazolopyridinylbenzamide and -sulfonamide inhibitors of B7-1

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210089290A (ko) 2020-01-07 2021-07-16 한국과학기술연구원 신규한 1-페닐-1h-피라졸 유도체 및 이의 용도
WO2023002011A1 (fr) * 2021-07-23 2023-01-26 Institut National De La Sante Et De La Recherche Medicale (Inserm) Inhibiteurs de pompe d'efflux de bactéries à gram négatif

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Publication number Publication date
KR20170107404A (ko) 2017-09-25
WO2017160069A1 (fr) 2017-09-21

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