KR101883737B1 - Banding Adhesive Composition Having Capsaicin Oil Capsule and Sports Taping Functional Band Thereof - Google Patents

Abstract

The present invention relates to a pressure-sensitive adhesive composition for bending comprising a capsaicin oil encapsulated in a sustained-release encapsulated oil capsule using a capsaicin oil as a capsule wall material and gradually releasing a drug substance, and a functional band for sports taping comprising the same Specifically disclosed is a capsaicin oil capsule comprising 10 to 50 parts by weight of capsaicin oil capsules per 100 parts by weight of a polyurethane adhesive, and a functional band for sports taping comprising the same.

Description

[0001] The present invention relates to a pressure-sensitive adhesive composition for banding comprising capsaicin oil capsules, and a functional band for sports taping comprising the same.

The present invention relates to a pressure-sensitive adhesive composition for bending comprising a sustained release encapsulated capsaicin oil capsule which slowly releases a pharmacological substance by using a capsaicin oil as a capsule wall material with a biodegradable polymer compound, and a functional band for sports taping comprising the same.

Nowadays, modern people suffer from pain caused by various factors. Various causes such as exercise or work, improper posture, mental stress can cause muscle strain and cause pain. In this way, the muscles are tensed or damaged and the muscles are swollen and the circulation of the frontal tube, the lymph and the tissue fluid can not be smoothly performed, thereby causing pain. In this case, when the tape having the performance similar to the stretchability of the muscle is stuck to the painful area, the space of the skin and the muscle is increased to increase the circulation of the blood and the lymph fluid and the tissue fluid to alleviate the pain, Can help mitigate. It is called taping therapy to help relieve pain by attaching specially treated tape like this.

Taping therapy is to tape the affected muscles to normalize the movements of the muscles of the moving muscles and to promote the circulation of blood, lymph and tissue fluids, which can suppress or promote muscle tension Kinesiotaping, which is a flexible tape especially as a functional tape, is used for therapeutic purposes by increasing the blood and lymph circulation between the muscles and the skin by attaching the joints to the settlement of the moving muscles, thereby improving the muscular movement function.

These Kinesio taping therapies are used in various ways in daily life as well as sports, and can be applied without any particularly worrisome side effects.

However, most sports taping currently is limited to the physical treatment of muscles as described above, and there is a lack of research on techniques that can easily combine physical therapy with physical therapy of muscles.

1. Korean Utility Model Registration No. 20-0481992 2. Korean Patent Registration No. 10-0617874

In the present invention, capsaicin oil, which is known to have a diet effect by increasing the heat production of the body and increasing energy consumption, fatigue recovery, skin beauty, immunity enhancement, stress relief, pain relief and blood circulation, Encapsulating the adhesive composition into a pressure sensitive adhesive composition for bending, and introducing the adhesive composition into an adhesive layer of a tape used for sports banding to obtain a physical treatment effect of muscles by taping, There is provided a pressure-sensitive adhesive composition for banding comprising a capsaicin oil capsule used for therapeutic or prophylactic purposes which effectively absorbs the injury caused by sports taping by being absorbed by the skin, thereby to provide a functional band for sports taping The Challenge The.

The pressure-sensitive adhesive composition for bending comprising capsaicin oil capsules of the present invention which solves the above problems is characterized in that 10 to 50 parts by weight of capsaicin oil capsules are mixed with 100 parts by weight of an adhesive.

Herein, the capsaicin oil capsule is produced by the following production method.

Polycarboxylic lactose (PCL), capsaicin oil, and polyvinyl alchohol (PVA) were put into a homogenizer at a temperature of 25 ± 5 ° C, at 5,000-8,000 rpm Mixing the mixture at a stirring speed of the raw material mixing step to produce a mixed solution;

Forming a wall material outside the capsaicin oil by evaporating the mixed raw material in a reduced pressure environment at a temperature of 40 to 60 ° C for 2 to 3 hours;

After formation of the wall material, filtration or precipitation to obtain microsized capsaicin oil capsules

Here, in the raw material mixing step, 3 to 6 parts by weight of polycarboxylic lactose, 3 to 6 parts by weight of capsaicin oil and 1.5 to 3 parts by weight of polyvinyl alcohol are mixed with 100 parts by weight of dichloromethane.

Here, the coating thickness of the capillary oil capsule wall material is formed to have a thickness of 1.5 to 3.0 탆.

Here, the capsaicin oil capsules have an average size of 3.5-11.0 μm.

The present invention includes a pressure-sensitive adhesive composition as described above, which comprises a base tape 100, a pressure-sensitive adhesive layer 200 coated on the surface of the base tape 100 to a predetermined thickness, And a releasing paper (300) attached thereto.

Here, the pressure-sensitive adhesive layer comprises 9.0 to 33.4 wt% capsaicin oil capsules based on the total amount of the pressure-sensitive adhesive.

Here, the moisture permeability of the capsaicin oil of the band is 7.6 to 7.8 g / m < 2 >.

According to the present invention, by applying the adhesive composition provided in the present invention to a pressure-sensitive adhesive layer constituting a sports tape used for physical therapy or prophylactic use of muscles, the use of a tape used in sports taping therapy can be used for physical treatment As well as preventive effect. The capsaicin of the capsaicin oil capsule contained in the adhesive is slowly absorbed into the skin, thereby providing the pharmacological effect of activating the blood circulation.

FIG. 1 is a process diagram showing an example of a manufacturing process of a camshaft oil capsule according to an embodiment of the present invention.
FIG. 2 is an electron micrograph of capsaicin oil capsules prepared according to the manufacturing process of FIG. 1; FIG.
3 is a cross-sectional view of a sports banding tape according to an embodiment of the present invention.
FIG. 4 is an electron micrograph showing cracking of a wall material during the process of manufacturing capsaicin oil capsules constituting the present invention. FIG.
Figure 5 shows an example of an apparatus for processing capsaicin oil capsules of the present invention.

BRIEF DESCRIPTION OF THE DRAWINGS The present invention will be described in more detail with reference to the accompanying drawings.

The present invention discloses a pressure-sensitive adhesive composition for bending comprising a capsaicin oil capsule encapsulated in a sustained-release type in which a capsaicin oil is slowly released as a capsule wall material using a biodegradable polymer compound and a functional band for sports taping comprising the same .

Capsaicin oil, which is constituted in order to complete the present invention, is known to have the pharmacological effect described below. When capsaicin oil capsules are made into sustained release capsules using biodegradable polymeric compounds, capsaicin oil is gradually absorbed And it is possible to obtain a sufficient pharmacological effect of capsaicin oil.

≪ Pharmacological effect of capsaicin oil >

1. Diet effect

Capsaicin activates adipose tissue, burns fat, stimulates the sympathetic nervous system in the body, makes blood flow easier, increases body temperature, increases heat, increases energy consumption and helps dieting.

2. Fatigue, skin beauty, immunity enhancement

In particular, capsaicin extracted from red pepper is rich in vitamin C, so it is effective for fatigue recovery, skin beauty and immunity are increased, and it does not catch cold well.

3. Stress relief

When capsaicin is ingested, the metabolism becomes active and the blood flow increases, making it feel as though it is exercise and the feeling of refreshing. In particular, it stimulates the cranial nerves and distributes endorphins to relieve stress.

4. Pain Relief and Blood Circulation

It alleviates pain such as neuralgia and arthritis, and promotes blood circulation to help prevent various vascular diseases.

5. Anti-cancer effect

Capsaicin helps prevent and treat cancer, prevents cancer cells from growing into the tumor, and prevents cancer from spreading to other parts of the body.

The inventors of the present invention have found that by encapsulating and incorporating capsaicin oil into the pressure sensitive adhesive layer while forming a functional band for sports tapes, It is expected that pharmacological effects such as muscle pain relief and blood circulation promotion can be expected as well as the effect of the present invention.

The pressure-sensitive adhesive composition for bending comprising capsaicin oil capsules according to the present invention is characterized in that 10 to 50 parts by weight of capsaicin oil capsules are mixed with 100 parts by weight of the adhesive.

At this time, the adhesive to be used for the band is usually used. Preferably, the adhesive is selected from the group consisting of an acrylic adhesive, a polyurethane adhesive, a silicone adhesive, and a styrene-butadiene adhesive. It is more preferable to use a polyurethane adhesive to give a stretchability comparable to that of human skin.

When the mixing amount of the capsaicin oil capsules is less than 10 parts by weight, the content of the capsules when the adhesive is applied to the base tape is too small to obtain the expected pharmacological effect of release of capsaicin. When the amount of the capsaicin oil capsules exceeds 50 parts by weight, However, the adhesive force of the pressure-sensitive adhesive may deteriorate and peeling may easily occur when the adhesive is adhered to the skin.

According to the present invention, the capsaicin oil capsule is characterized by being produced by the following production method.

Polycarboxylic lactose (PCL), capsaicin oil and polyvinyl alchohol (PVA) were fed into a homogenizer at a temperature of 25 ± 5 ° C for 5,000 ~ A raw material mixing step of mixing the mixture at a stirring speed of 8,000 rpm to produce a mixed solution;

Forming a wall material outside the capsaicin oil by evaporating the mixed raw material in a reduced pressure environment at a temperature of 40 to 60 ° C for 2 to 3 hours;

After formation of the wall material, filtration or precipitation to obtain microsized capsaicin oil capsules

Referring to FIG. 1,

The biodegradable polymer PCL and the capsaicin oil, which are the core material, are first introduced into the homogenizer sequentially as the organic solvent DCM and the wall material, PVA is added as a dispersant for dispersing the capsaicin oil, . Preferably, capsaicin oil capsules are mixed at a stirring rate of 5,000 to 8,000 rpm at a temperature of 25 ± 5 ° C to nano-size the capsaicin oil capsules. If the capsaicin oil is outside the critical temperature range, If the agitation speed is less than 5,000 rpm, there is a problem that the components are not mixed well and the PCL is accumulated. When the stirring speed is more than 8,000 rpm, the capsaicin oil There is a problem that the wall material formed on the outside is broken.

At this time, the capsaicin oil should be mixed so that PCL as a wall material can be sufficiently coated, and preferably, the mixture is sufficiently stirred for 5 hours or more, preferably 3 to 5 hours. If it is less than 3 hours, there is a problem that the coating of PCL is not sufficiently carried out and the wall material is not formed well. If it exceeds 5 hours, the wall material is formed but it is coated too thinly, , Or when applied to a band for final sports taping, the skin absorption rate of capsaicin oil becomes too fast, so that sufficient pharmacological effect can not be obtained, or an unexpected side effect may occur due to rapid absorption .

After the mixed solution is formed, the organic solvent is evaporated for a certain period of time at a predetermined temperature range under a reduced pressure environment to form a capillary oil coated with the PCL layer to solidify the capillary oil to form a wall material, which is then filtered with a filter or precipitated for a predetermined time After removing the filtrate, a bead-shaped capsaicin oil capsule having a nano-sized size is obtained as shown in Fig.

In the DCM evaporation of the mixed solution, a vacuum pump and a pressure meter are installed in the homogenizer, the temperature of the homogenizer is raised to a range of 40 to 60 ° C, and the vacuum is gradually reduced by a vacuum pump. At this time, the evaporated DCM is discharged to the outside by a vacuum pump. The discharged DCM is separately obtained in a usual manner. More preferably, the mixed solution is transferred into an Erlenmeyer flask having a fixed capacity as exemplified in FIG. 5 and equipped with a pressure gauge and a connecting tube connected to a vacuum pump, sealed, and then heated to a temperature of 40 to 60 ° C It is good to go through the process of evaporation.

According to the present invention, since the DCM may remain in the capsaicin oil capsules obtained after the wall formation is completed through the evaporation process, the washing process is preferably performed after removing the DCM and washing with distilled water two to three times It is good practice to do more to remove the DCM completely.

It is also preferable that the stirring and mixing time is 2 to 3 hours under the preferable conditions. The reason for this is that in the case of less than 2 hours, the evaporation of DCM as an organic solvent is not completely performed, and thus there is a disadvantage in that an organic solvent remains in the product, and if it exceeds 3 hours, capsaicin oil capsules formed may be disadvantageous .

According to the present invention, preferably, the mixing ratio of the ingredients injected in the raw material mixing step to produce the capsaicin oil capsules is such that 36 parts by weight of polycarboxylic lactose, 3 to 6 parts by weight of capsaicin oil is added per 100 parts by weight of dichloromethane, And 1.5 to 3.0 parts by weight of polyvinyl alcohol are mixed.

When the amount of the dichloromethane is less than 85 parts by weight, the capsaicin oil and the PCL are not mixed well. When the amount is more than 170 parts by weight, capsaicin oil outer wall material is difficult to form.

When the mixing amount of the polycarboxylic lactose forming the wall material is less than 3 parts by weight, the capsaicin oil outer wall material is thinly formed as shown in FIG. 4, The capsaicin oil outer wall is too thick to release capsaicin oil.

When the mixing amount of the capsaicin oil is less than 3 parts by weight, the capsaicin oil capsules have a wall thickness that is too thick. When the capsaicin oil is more than 6 parts by weight, the capsaicin oil capsules have too small a wall thickness .

When the mixing amount of the polyvinyl alcohol used as the dispersing agent is less than 1.5 parts by weight, the stability of the mixed solution may be lowered and the mixing may not be performed uniformly. Thus, there is a problem that capsule formation is not performed well. There is a problem that mixing is too good and capsule formation is difficult.

According to the present invention, it is preferable that the coated wall material formed by coating the capsaicin oil capsule according to the present invention is formed to have a thickness of 1.5 to 3.0 탆. If the thickness is less than 1.5 占 퐉, there is a problem that the wall material easily opens as shown in Fig. 4, and when it is more than 3.0 占 퐉, it is difficult to release capsaicin oil as a pharmacological material have.

According to the present invention, it is preferable that the capsaicin oil capsules have an average size of 3.5-11.0 μm. This is because when the average size is maintained, the release rate of capsaicin oil and the holding state of the capsule are excellent. If the size is less than 3.5 탆, the capsules are easily damaged and it is difficult to maintain the capsules in a capsule state. It is difficult to release the pharmacological substance.

According to the present invention, a pressure-sensitive adhesive composition according to the present invention as described above is applied. As shown in FIG. 3, the pressure-sensitive adhesive composition of the present invention includes a base tape 100, And a releasing paper 300 attached to the top surface of the pressure-sensitive adhesive layer 200. The functional band for sports taping according to the present invention can be applied to a sports tape.

More specifically, as shown in FIG. 3, a pressure-sensitive adhesive composition comprising capsaicin oil capsules provided in the present invention is coated on one surface of a base tape 100 to have a predetermined thickness to form a pressure-sensitive adhesive layer 200 And a release paper 300 is attached to the upper surface thereof to form a band.

In addition, the release paper 300 may not be formed according to the shape of the final object in the manufacturing process, that is, in the case of a roll type tape commonly used.

At this time, it is preferable that the pressure-sensitive adhesive layer contains 9.0 to 33.4 wt% capsaicin oil capsules based on the total amount of the pressure-sensitive adhesive. (Here, the content of the capsules is about 9.0 wt% when the polyurethane adhesive: , And when it is 100: 50, it becomes about 33.4 wt%.)

According to the present invention, the functional band of the capsaicin oil has a moisture permeability of 7.6 to 7.8 g / m < 2 > to provide a functional band having excellent moisture permeability of the capsaicin oil.

The capsaicin oil capsules constituting the pressure-sensitive adhesive composition according to the present invention described above were manufactured by adjusting the wall thicknesses of the capsules as shown in Table 1 below, and the capsaicin oil capsules and the polyurethane adhesives were prepared as shown in Table 1 below By weight to prepare a pressure-sensitive adhesive composition. The prepared pressure-sensitive adhesive composition was prepared with a base tape and a coating layer of a pressure sensitive adhesive was applied on one side of the fabric to a thickness of 3 to 15 탆 to prepare a functional band for sports tape .

The capsaicin oil skin permeation test of the prepared band was performed, and the results are shown in Table 1 below.

In the skin permeation test, the moisture permeability of the adhesive layer was measured, and it was related to the rate at which the oil contained in the capsaicin oil capsules contained in the adhesive layer was released to the outside. Using the Franz cell analyzer, the permeability of capsaicin The amount was measured.

At this time, a transdermal diffusion test model (size 25 mm Discs, Qty: 60) similar to the human skin was used as the permeable membrane for transdermal absorption. The amount of capsaicin absorbed into water after 24 hours at a temperature similar to body temperature Were measured. The amount of capsaicin absorbed into water was measured by ultraviolet spectroscopy, and the amount of capsaicin eluted by comparing the absorbance at a certain wavelength band with the black concentration was determined. The results are shown in Table 1 below.

Capsule wall material thickness (㎛) Adhesive: Capsule (parts by weight) Water vapor permeability (g / ㎡) 1.5 100: 10 7.792 1.5 100: 25 7.786 1.5 100: 50 7.791 2.5 100: 10 7.711 2.5 100: 25 7.710 2.5 100: 50 7.707 3.0 100: 10 7.677 3.0 100: 25 7.664 3.0 100: 50 7.676

According to the above Table 1, the thinner the capsaicin oil capsule wall material is, the higher the moisture permeability is, and the mixing ratio of the capsaicin oil capsule and the adhesive has little influence on the moisture permeability.

As described above, by applying the adhesive composition provided in the present invention to a pressure-sensitive adhesive layer constituting a sports tape used for physical therapy or prophylactic use of muscles, the use of a tape used for sports taping therapy enables physical treatment Or preventative effects as well. The capsaicin of capsaicin oil capsules contained in the pressure-sensitive adhesive is gradually absorbed into the skin, thereby obtaining a pharmacological effect that activates blood circulation.

100: Base tape
200: pressure-sensitive adhesive layer
300: release paper
210: capsaicin oil capsules

Claims (9)

A pressure-sensitive adhesive composition for forming a pressure-sensitive adhesive layer of a sports tape,
Wherein 10 to 50 parts by weight of capsaicin oil capsules are mixed with 100 parts by weight of the adhesive,
The capsaicin oil capsule may contain,
Polycarboxylic lactose (PCL), capsaicin oil, and polyvinyl alchohol (PVA) were put into a homogenizer at a temperature of 25 占 폚 to 5,000 占 폚 for 5,000 to 8,000 rpm Mixing the mixture at a stirring speed of the raw material mixing step to produce a mixed solution;
Forming a wall material outside the capsaicin oil by evaporating the mixed raw material in a reduced pressure environment at a temperature of 40 to 60 ° C for 2 to 3 hours;
After formation of the wall material, filtration or precipitation to obtain microsized capsaicin oil capsules;
Wherein the capsaicin oil capsule is prepared by a method of manufacturing a capsaicin oil capsule.
delete The method according to claim 1,
The capsaicin oil capsule according to claim 1, wherein the capsaicin oil capsule is washed with distilled water two or three times.
The method according to claim 1,
In the raw material mixing step, 3 to 6 parts by weight of polycarboxyl lactose, 3 to 6 parts by weight of capsaicin oil and 1.5 to 3.0 parts by weight of polyvinyl alcohol are mixed with 100 parts by weight of dichloromethane. And a pressure-sensitive adhesive layer.
The method according to claim 1,
Wherein the capsaicin oil capsule has a coating thickness of 1.5 ~ 3.0 mu m. [3] The capsaicin oil capsule according to claim 1,
The method according to claim 1,
Wherein the capsaicin oil capsules have an average size of 3.5 to 11.0 占 퐉.
A pressure-sensitive adhesive composition comprising a base tape (100) and a pressure-sensitive adhesive layer (100) coated on one surface of the base tape (100) 200, and a releasing paper (300) attached to an upper surface of the pressure sensitive adhesive layer (200).
8. The method of claim 7,
Characterized in that the pressure sensitive adhesive layer comprises from 9.0 to 33.4 wt% capsaicin oil capsules based on the total amount of the pressure sensitive adhesive.
8. The method of claim 7,
Wherein the capsaicin oil of the band satisfies a moisture permeability of 7.6 to 7.8 g / m < 2 >.

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