KR101855395B1 - 근적외선을 이용한 폐종양 스크리닝 방법 - Google Patents
근적외선을 이용한 폐종양 스크리닝 방법 Download PDFInfo
- Publication number
- KR101855395B1 KR101855395B1 KR1020160123392A KR20160123392A KR101855395B1 KR 101855395 B1 KR101855395 B1 KR 101855395B1 KR 1020160123392 A KR1020160123392 A KR 1020160123392A KR 20160123392 A KR20160123392 A KR 20160123392A KR 101855395 B1 KR101855395 B1 KR 101855395B1
- Authority
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- South Korea
- Prior art keywords
- infrared rays
- chest wall
- tumor
- near infrared
- present
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 50
- 238000012216 screening Methods 0.000 title claims abstract description 31
- 208000037841 lung tumor Diseases 0.000 title claims abstract description 26
- 208000020816 lung neoplasm Diseases 0.000 title claims description 18
- 206010072960 Chest wall tumour Diseases 0.000 claims abstract description 45
- 208000018223 neoplasm of chest wall Diseases 0.000 claims abstract description 45
- 210000000779 thoracic wall Anatomy 0.000 claims abstract description 20
- 206010028980 Neoplasm Diseases 0.000 claims description 14
- 239000007850 fluorescent dye Substances 0.000 claims description 14
- 210000004204 blood vessel Anatomy 0.000 claims description 10
- 239000013307 optical fiber Substances 0.000 claims description 10
- MOFVSTNWEDAEEK-UHFFFAOYSA-M indocyanine green Chemical group [Na+].[O-]S(=O)(=O)CCCCN1C2=CC=C3C=CC=CC3=C2C(C)(C)C1=CC=CC=CC=CC1=[N+](CCCCS([O-])(=O)=O)C2=CC=C(C=CC=C3)C3=C2C1(C)C MOFVSTNWEDAEEK-UHFFFAOYSA-M 0.000 claims description 9
- 229960004657 indocyanine green Drugs 0.000 claims description 9
- 238000003384 imaging method Methods 0.000 claims description 8
- 206010029113 Neovascularisation Diseases 0.000 claims description 4
- 230000005284 excitation Effects 0.000 claims description 3
- 230000001678 irradiating effect Effects 0.000 claims description 3
- 230000002685 pulmonary effect Effects 0.000 claims description 3
- 238000003780 insertion Methods 0.000 claims description 2
- 230000037431 insertion Effects 0.000 claims description 2
- 230000005855 radiation Effects 0.000 claims description 2
- 238000010521 absorption reaction Methods 0.000 claims 1
- 238000013399 early diagnosis Methods 0.000 abstract description 7
- 208000006178 malignant mesothelioma Diseases 0.000 abstract description 7
- 206010063599 Exposure to chemical pollution Diseases 0.000 abstract description 2
- 238000002405 diagnostic procedure Methods 0.000 abstract description 2
- 230000003211 malignant effect Effects 0.000 abstract description 2
- 210000004224 pleura Anatomy 0.000 description 12
- 238000010171 animal model Methods 0.000 description 5
- 238000010586 diagram Methods 0.000 description 5
- 210000004072 lung Anatomy 0.000 description 5
- 239000010425 asbestos Substances 0.000 description 3
- 210000000038 chest Anatomy 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 3
- 229910052895 riebeckite Inorganic materials 0.000 description 3
- 201000008827 tuberculosis Diseases 0.000 description 3
- 238000002835 absorbance Methods 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 238000002591 computed tomography Methods 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 238000011587 new zealand white rabbit Methods 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 238000004497 NIR spectroscopy Methods 0.000 description 1
- 206010035600 Pleural fibrosis Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000000711 cancerogenic effect Effects 0.000 description 1
- 231100000357 carcinogen Toxicity 0.000 description 1
- 239000003183 carcinogenic agent Substances 0.000 description 1
- 101150047356 dec-1 gene Proteins 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000000799 fluorescence microscopy Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 201000005202 lung cancer Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 210000004303 peritoneum Anatomy 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 238000010837 poor prognosis Methods 0.000 description 1
- 238000002600 positron emission tomography Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 210000001562 sternum Anatomy 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000000107 tumor biomarker Substances 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
- G01N21/359—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57423—Specifically defined cancers of lung
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- Medical Informatics (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020160123392A KR101855395B1 (ko) | 2016-09-26 | 2016-09-26 | 근적외선을 이용한 폐종양 스크리닝 방법 |
| PCT/KR2017/008771 WO2018056574A1 (fr) | 2016-09-26 | 2017-08-11 | Procédé de dépistage de tumeur pulmonaire au moyen de rayons infrarouges proches |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020160123392A KR101855395B1 (ko) | 2016-09-26 | 2016-09-26 | 근적외선을 이용한 폐종양 스크리닝 방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20180033878A KR20180033878A (ko) | 2018-04-04 |
| KR101855395B1 true KR101855395B1 (ko) | 2018-05-09 |
Family
ID=61690475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020160123392A KR101855395B1 (ko) | 2016-09-26 | 2016-09-26 | 근적외선을 이용한 폐종양 스크리닝 방법 |
Country Status (2)
| Country | Link |
|---|---|
| KR (1) | KR101855395B1 (fr) |
| WO (1) | WO2018056574A1 (fr) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101460908B1 (ko) | 2013-08-09 | 2014-11-17 | 서울여자대학교 산학협력단 | 4차원 컴퓨터 단층촬영 영상의 폐종양 위치 추적 시스템 및 그 방법 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4445065A1 (de) * | 1994-12-07 | 1996-06-13 | Diagnostikforschung Inst | Verfahren zur In-vivo-Diagnostik mittels NIR-Strahlung |
| US20080218732A1 (en) * | 2005-07-27 | 2008-09-11 | University Of Massachusetts Lowell | Infrared Scanner for Biological Applications |
| CA2784576C (fr) * | 2009-12-15 | 2020-01-07 | Shuming Nie | Systeme et methodes permettant de livrer une aide directionnelle anatomique en temps reel pour un diagnostic ou une intervention therapeutique |
| US20130211246A1 (en) * | 2011-12-27 | 2013-08-15 | Vinod PARASHER | METHODS AND DEVICES FOR GASTROINTESTINAL SURGICAL PROCEDURES USING NEAR INFRARED (nIR) IMAGING TECHNIQUES |
| US10376148B2 (en) * | 2012-12-05 | 2019-08-13 | Accuvein, Inc. | System and method for laser imaging and ablation of cancer cells using fluorescence |
-
2016
- 2016-09-26 KR KR1020160123392A patent/KR101855395B1/ko active IP Right Grant
-
2017
- 2017-08-11 WO PCT/KR2017/008771 patent/WO2018056574A1/fr active Application Filing
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101460908B1 (ko) | 2013-08-09 | 2014-11-17 | 서울여자대학교 산학협력단 | 4차원 컴퓨터 단층촬영 영상의 폐종양 위치 추적 시스템 및 그 방법 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018056574A1 (fr) | 2018-03-29 |
| KR20180033878A (ko) | 2018-04-04 |
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