KR101846941B1 - Feed composition with nipa fruticans wurmb - Google Patents

Abstract

The present invention relates to a feed composition using nipagaya, and more particularly to a feed composition using nipaya as an active ingredient.
According to the feed composition of the present invention, the antioxidant and antimicrobial activity are excellent, and thus it is possible to replace the livestock antibiotic.

Description

[0001] FEED COMPOSITION WITH NIPA FRUTICANS WURMB [0002]

The present invention relates to a feed composition using nipagaya, and more particularly, to providing a feed composition having antioxidant and antimicrobial activity by forming a feed using a nipah palaceae.

The use of growth promoting antibiotics in livestock feeds is aimed at maximizing livestock productivity, preventing high-density breeding and disease caused by poor breeding environments.

However, antibiotics injected into feeds are completely extinguished only after 2 ~ 3 months. When they are shipped and eaten before such a period of abstinence, there is a problem that the immunity of the human body consumed with the meat product is lowered due to the residual antibiotics in the livestock. In addition, there is a problem that bacteria having resistance to antibiotics are increased.

Due to these reasons, recently, antibiotic resistant bacteria in the meat products have been accompanied by problems with the antibiotic resistant bacteria, and researches on antibiotic substitutes have been actively carried out. As a substitute for antibiotics, Are being studied actively.

More specifically, examples include probiotics, acidifiers, enzymes, mineral additives, and oligosaccharides.

In addition, various substances using useful substances in plants have been used as an antibiotic substitute, but the effect thereof is not satisfactory. In general, antimicrobial and antioxidant components are widely used as antibiotic substitutes. Antioxidants are used for the purpose of suppressing harmful microorganisms in the intestines. However, in the case of antibiotics substitute materials currently in development, if the manufacturing cost is high or the cost is low, it is difficult to commercialize antibiotics substitute materials due to insufficient substitution effect.

KR 10-1164927 B1

Accordingly, an object of the present invention is to provide a feed composition which is excellent in economic efficiency so as to be able to replace antibiotics in the past, has no restriction on feeding of livestock, and has excellent antioxidant and antimicrobial activity.

In order to accomplish the above object, the present invention provides a feed composition comprising nipaya as an active ingredient.

Characterized in that it further comprises a flower bud extract of Nipaya as an active ingredient.

Wherein the nipponophyll phalaenopsis powder comprises a step of cutting a nipponia palm flower bed, a step of salting the cut flower pedestal with a salinity of 8 to 12%, a step of aging the salted flower pedestal for 40 to 60 hours, A step of dewatering the primary dehydrated flower bed in water, a step of secondary dehydrating the dehydrated flower bed, a step of adjusting the salinity of the secondary dehydrated flower bed to 0.3 to 0.8% Drying the pedicel having the salinity adjusted; and pulverizing the dried pedicel to 200 to 300 mesh.

The extract of the nifa palm phlox is composed of a step of cutting a flower bud of nifayja, a step of hot water extraction or ultrasonic extraction using a flower bud of the cut nifaya flower as a solvent, and a step of concentrating the extracted extract And the like.

Wherein the extract of the nifeliana palisade is prepared as a powder by further comprising a step of concentrating the extracted extract and lyophilizing the extracted extract.

Wherein the phloem powder of the nippae is contained in an amount of 1 to 5% by weight of the total feed composition.

The phloem extract of Nipaya is contained in an amount of 1 to 5% by weight of the total feed composition.

According to the feed composition of the present invention, the antioxidant and antimicrobial activity are excellent, and thus it is possible to replace the livestock antibiotic.

In addition, there is an advantage that the weight of livestock can be easily increased by increasing feeding of livestock.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a process for producing a nifa palm phalaenopsis powder according to the present invention. FIG.
2 to 5 are graphs showing the results of Test Example 2 according to the present invention.

Hereinafter, the present invention will be described in detail.

The feed composition according to the present invention is characterized by containing a powder of a nifa palm phalanx as an active ingredient.

Here, the feed composition can be used as feed for livestock, that is, for cattle, pigs, as well as for chickens, ducks, and the like, and the kind of livestock is not limited.

First, the above-mentioned NIPA FRUTICANS WURMB is originated in India, Malaysia, Southeast Asia and Australia, and grows in mangroves and other wetlands. The roots are divided into several pieces in the ground, and the leaves are gathered on the ground and have a glossy green color. And the flower is one male and one female, and it comes out from the axilla of the ground. Usually, the flower stands rise from October to June of the following year.

The present invention uses such a flower bud of Nipaya as a powder, and in particular, the reason why the flower bud of Nipaya is used is that the antioxidant component such as polyphenol, selenium, It is because it contains a lot of various nutrients.

The results of the analysis and the results of the components of the above-mentioned Nihonpalaceae are shown in the following Tables 1 and 2. As shown in Table 1 and Table 2, the Niha-Paya's peduncle contains a large amount of effective components such as polyphenol, flavonoid, saponin, as well as aspartic acid, tyrosine and histidine .

The results of analysis of the components of. Inspection items unit test results Inspection items unit test results moisture % 20.54 Selenium Mu g / kg 154.57 Crude protein % 11.65 manganese mg / kg 82.58 Crude fat % 0.73 Goat mg / kg 18344.65 Views min % 7.95 sulfur mg / kg 3221.83 carbohydrate % 59.15 salt mg / kg 6832.66 calorie kcal / 100g 289.77 Crude saponin mg / kg 110161.07 calcium mg / kg 3009.62 Total polyphenol Brix 173443.90 sign mg / kg 2589.65 Total flavonoid mg / kg 616.24 iron mg / kg 119.57 Per capita % 11.84 potassium mg / kg 26211.57 And sugar % 1.57 magnesium mg / kg 4670.47 glucose % 1.11 Copper mg / kg 0.26 saccharose % 1.19 zinc mg / kg 14.13

Test results of the components of the nipponia palm. Inspection items unit test results Aspartic acid mg / kg 269.01 Threonine mg / kg 30.22 Serine mg / kg 30.59 Glutamic acid mg / kg 171.29 Proline mg / kg 0 Glycine mg / kg 7.98 Alanine mg / kg 25.69 Balin mg / kg 49.06 Isoleucine mg / kg 39.30 Leucine mg / kg 49.73 Tyrosine mg / kg 0 Phenylmalanine mg / kg 14.70 Histidine mg / kg 13.44 Lysine mg / kg 16.26 Arginine mg / kg 302.53 Cystine mg / kg 30.19 Methionine mg / kg 32.46 Tryptophan mg / kg 0

Therefore, if such a nifa palm flower is contained as an active ingredient of a feed composition, antioxidant and antimicrobial activity is imparted to the feed composition, thereby enhancing the immunity of domestic animals and replacing antibiotics conventionally used.

If the amount is too small, the antioxidant and antimicrobial activity will be insufficient. If the amount is excessive, it will affect the feeding of livestock It is preferable to include them in the above amounts.

As shown in Fig. 1, the nipponaya peduncle powder is prepared by cutting a nipponia cinnabar, a step of salting the cut cinnabar with a salinity of 8-12%, a step of aging the cinnabar for 40-60 hours A step of first dehydrating the aged flower buds, a step of soaking the first dehydrated flower buds in water, a second dehydrating step of the sea buds, and a step of dehydrating the second dehydrated flower buds Adjusting the salinity to 0.3 to 0.8%, drying the pedicel having the salinity adjusted, and pulverizing the dried pedicel to 200 to 300 mesh. In addition, before the salting step, it may further include a step of tearing the cut flower stalk for 20 to 40 minutes in boiling water, a step of tearing the spiked flower stalk in the longitudinal direction, and a step of dewatering the torn flower stalk.

This will be described in detail as follows.

First, pick up the nipaya japonica, clean it, and cut it to a length of 3-10cm.

Next, salt is added to the cut flower stalk so as to have a salinity of 8 ~ 12%, and salted and matured at room temperature for 40 ~ 60 hours. Here, the salting and maturing step is to sufficiently remove water from the flower bed through the salting. In other words, the salty and maturing to maintain a crispy texture while the softer form of the peduncle is to be.

In addition, water is generated by osmotic pressure in the process of aging of the flower bud. First, the aged flower bud is dehydrated to remove the effluent generated during the aging process.

Next, the primary dehydrated flower stalk is immersed in water to be sun dried. Here, the above-mentioned sea salt time is sufficient for about 20 to 30 hours, and the amount and temperature of water are not limited. However, for fast sea salt, hot water of 30 ~ 40 ℃ can be used and enough water is used to sufficiently immerse the primary dehydrated flower bed. In this process, together with sodium, the tannin component of the nifa palm phlox is also eluted, so that the whitish taste of the nipponia is removed, and the flavor of the feed composition is also improved. Although the tannin is a kind of polyphenol, the antioxidant effect of the nihama cinnabar is not significantly deteriorated because a large amount of other polyphenols are present even when the tannin is removed.

Then, the sea bass is dehydrated secondarily, and salt is added to the second dehydrated flower bed to adjust the salinity to 0.3 to 0.8%. This is for the overall salinity of the feed composition.

The dried flower buds were dried to a moisture content of 5 to 10% by hot air drying, cold wind drying and daylight natural drying method. The dried flower buds were dried at 200 to 300 mesh using a pulverizer or a squeezer By pulverizing, the production is completed.

Meanwhile, as mentioned above, after cutting the peduncle, the cut peduncle is heated in boiling water, that is, water at 100 ° C for 20 to 40 minutes. After the beaten peduncle is immersed in cold water and cooled, , Tear it long enough, dehydrate it, and then salting it. At this time, the thickness is preferably about 0.5 to 1 cm. The nipayanaya peduncle is easily torn as easily because it has parallel longitudinal texture.

In the present invention, the dewatering method is not limited, and it is natural that a dewatering device for food can be used or water can be removed by hand-wringing.

In addition, the feed composition of the present invention may further comprise a fimbriae extract of nifayja as an active ingredient, wherein the nepalese flower bud extract may be contained in an amount of 1 to 5% by weight of the total feed composition. That is, the further inclusion of the phloem extract of Nipaya can improve the antioxidant and antimicrobial activity of the nipayanas, but also improve the feedability of the feed, thereby increasing the feeding amount of livestock.

At this time, the flower bud extract of Nipaya is cut into a size of 3 to 10 cm, and the flower bud of Nipaya is cut out by hot water extraction or ultrasonic extraction using water as a solvent, and then concentrated. It may also be prepared by concentrating, lyophilizing and pulverizing. The above-described freeze-drying follows a method known in the art, and a detailed description thereof will be omitted.

Here, the hot water extraction is a method of extracting water at a temperature of 80 to 100 ° C for 10 to 20 hours after adding water of about 10 to 20 times the weight of the flower bud of the above-mentioned Nepalaya, and ultrasonic extraction is performed at 8 to 12 times And the mixture is pre-treated for 20 to 30 minutes under the condition of about 100 to 150 kHz by using an ultrasonic wave extractor, and further subjected to hot water extraction for 10 to 12 hours at a temperature of 50 to 60 ° C.

In order to increase the extraction efficiency, the cut nipaya is subjected to natural drying, cold air drying or hot air drying to have a water content of 10 to 20%, followed by pulverization to a size of about 100 to 200 mesh, and extracting the active ingredient from the powder . In addition, it is also possible to dehydrate the cut nippa coconut palms in boiling water at 100 ° C for 10 to 20 minutes, dehydrate them, and extract the active ingredient therefrom.

The concentration means concentration under reduced pressure, and the solvent is removed at 50 to 60 ° C to concentrate the solution to about 20 to 50 Brix. The reason for concentrating the extract in the present invention is to increase the content of the functional substance through concentration and to reduce unnecessary water content. It is of course also possible to conduct filtration before concentration, if necessary.

In addition, the feed composition may further include a liquid concentrate of NiPhaya, wherein the liquid concentrate of NiPhaya can be contained in an amount of 1 to 3% by weight of the total feed composition. Further mixing of the liquid concentrate of the above-mentioned Nipaya extract has an advantage in that its antioxidative and antibacterial activity is further improved, and the feedability of the feed is improved and the amount of ingested food can be increased.

A method for producing the above-mentioned nipah-wax liquid concentrate is as follows.

First, you can get 500 to 700g of sap per night during the night if you cut a wound on the top of the nipa cradle and wrap it around the wounded area with a plastic bag or the like. The resulting liquid is heated at 60 to 80 ° C. for about 2 to 4 hours to concentrate the resulting liquid to a sugar content of 60 to 80 brix to prepare a concentrated liquid of nifaca. This nipah sasa liquid concentrate is dark brown in color and can feel a bitter but strong sweet taste.

The components of the nipah yam sap solution and the components of the nipah yam sap solution according to the present invention were analyzed and the results are shown in Tables 3 through 5 below. As can be seen from Tables 3 to 5, it can be seen that the nipah yam sap and its concentrate contain selenium having various excellent anticancer effects as well as a large amount of polyphenols and various active ingredients.

Analysis of composition of sap of nipah palm. Inspection items unit test results Inspection items unit test results moisture % 55.60 Goat mg / kg 2473.38 Crude protein % 0.29 sulfur mg / kg 91.78 Crude fat % 0.11 salt mg / kg 1362.97 Views min % 3.47 Total polyphenol mg / kg 869.57 carbohydrate % 40.53 Crude saponin mg / kg 2309.04 calorie kcal / 100g 164.27 pH 4.20 calcium mg / kg 11.95 Sugar content Brix 14.3 sign mg / kg 278.70 fruit sugar % 3.76 iron mg / kg 30.21 glucose % 2.70 potassium mg / kg 5585.72 saccharose % 5.12 magnesium mg / kg 110.85 Propionic acid % 0.22 Copper mg / kg 2.38 Acetic acid % 0.51 zinc mg / kg 2.68 Citric acid % 0.10 Selenium Mu g / kg 838.92 Formic acid % 0.61 manganese mg / kg 2.05 Naksan % 0.49

Analysis of the components of the nipah palm extract. Inspection items unit test results Inspection items unit test results moisture % 27.91 Goat Mu g / kg 14673.77 Crude protein % 1.25 sulfur mg / kg 469.30 Crude fat % 0.11 manganese mg / kg 4.20 Views min % 5.17 salt mg / kg 4358.02 carbohydrate % 68.56 Total polyphenol mg / kg 1262.67 calorie kcal / 100g 280.23 Crude saponin mg / kg 1407.11 calcium mg / kg 7.89 pH 5.21 sign mg / kg 471.13 Sugar content Brix 76.2 iron mg / kg 46.37 fruit sugar % 8.16 potassium mg / kg 10894.96 glucose % 8.47 magnesium mg / kg 226.85 saccharose % 49.39 Copper mg / kg 1.47 Propionic acid % 0.34 zinc mg / kg 5.48 Acetic acid % 6.33 Selenium Mu g / kg 234.03

The results of composition test of the nipah palm solution concentrate. Inspection items Free amino acid (mg / kg) Phosphoserine 141.68 Taurine 91.67 Phospho ethanol amine 689.59 Aspartic acid 1282.19 Theonine 139.32 Serine 392.93 Glutamic acid 1059.81 Proline 257.69 Glycine 26.45 Alanine 330.94 Citrulline 9.61 alpha -amino-n-butyric acid 1.82 Valine 197.69 Methionine 26.37 Cystathionine 29.66 Isoleucine 99.99 Leucine 68.93 Tyrosine 73.70 Phenylalanine 47.11 β-Alanine 141.26 β-Amino isobutyric acid 57.11 γ-Amino-n-bytyric acid 78.37 Ornithine 23.23 Lysine 156.70 Histidine 34.61 Arginine 210.53

The feed composition of the present invention as described above has the effect of increasing the immunity of domestic animals and replacing conventional antibiotics. In addition, the nutritional composition of the feed composition is also improved so that the feeding amount can be increased, so that the weight of the livestock can be easily increased.

Hereinafter, the present invention will be described in more detail with reference to specific examples.

(Production Example 1)

First, the nipponia palms were picked, cleaned and then cut into 10 cm lengths. Then, it was boiled in boiling water at 100 ° C for 30 minutes, and the vestibule was soaked in cold water and cooled. Next, the corolla was torn to a diameter of about 0.8 cm, and then dehydrated by putting it in a dehydrator. Then, salt was sprinkled to make the salinity to be 10%, and it was aged at room temperature for 48 hours in a plastic container. The aged flower buds were dehydrated secondarily, the second dehydrated flower buds were dipped in water at 30 ° C for 24 hours, and then dehydrated again. Then, salt was sprinkled on the third dehydrated flower bed to adjust the salinity to 0.5%, and then dried to a moisture content of 7% using a hot air drier at 60 ° C. Next, the dried peduncle was firstly pulverized by a pulverizer, and then pulverized in a second mill to prepare a powder having a particle size of 300mesh.

(Production Example 2)

The nipponia palms were picked, cleaned and then cut into 10 cm lengths. Dried by hot air at 50 캜 to have a water content of 15%, and pulverized to about 100 mesh. 20 wt. Parts of distilled water was added thereto, and the mixture was extracted at 90 to 100 캜 for 20 hours. After filtration, the filtrate was concentrated under reduced pressure at 50 ° C using a vacuum concentrator to obtain a concentrate of 32 Brix.

(Production Example 3)

The nipponia palms were picked, cleaned and then cut into 10 cm lengths. Dried by hot air at 50 ° C to give a water content of 15%, pulverized to about 100 mesh, 10-fold weight of distilled water was added thereto, and the mixture was pretreated with an ultrasonic wave extender at 120 kHz for 30 minutes. For 10 hours. After filtration, the filtrate was concentrated under reduced pressure at 50 ° C using a vacuum concentrator to obtain a concentrate of 32 Brix.

(Test Example 1)

Evaluation of Antioxidant Potential of Powder and Extract of.

The antioxidant power of the powder and extract prepared in Preparation Examples 1, 2 and 3 was measured.

The extracts of Preparation Examples 2 and 3 were concentrated in a rotary vacuum evaporator (EYELAA-1000S, Tokyo Rikakikai Co., Tokyo, Japan) at 40 ° C, dried and then used in the experiment.

(1) Measurement of DPPH radical scavenging ability

To determine the antioxidant activity, the Biois method was used to examine the radical scavenging effect of DDPH (1,1-diphenyl-2-picryhydrazyl, Sigma-Aldrich Co.). 1 ml of 0.2 mM DPPH was added to 1 ml of the sample solution prepared from 0.625 to 10 mg / ml of each extract, mixed using a vortex mixer, reacted for 30 minutes in a dark room, and absorbance was measured at 517 nm. Then, free radical scavenging activity curves were generated using the following equation, and IC ₅₀ was calculated. As a positive control, ascorbic acid was used.

Radical scavenging activity (%) = {(control Absorbance - Sample Absorbance) / control Absorbance} × 100

(2) Measurement of ABTS radical scavenging ability

ABTS radical scavenging activity was measured by Pellegrin et al. 5 ml of 7 mM ABTS (2,2'-azinobis (3-ethylenbenzothiazoline-6-sulfonate), Sigma-Aldrich Co.) and 88 μl of 140 mM K ₂ S ₂ O ₈ (Sigma-Aldrich Co.) .

The mixture was mixed with absolute ethanol at a ratio of 1:88, and the ABTS solution was prepared so that the absorbance of the control was adjusted to 0.7 ± 0.002 at 734 nm. 1 ml of ABTS solution was added to 50 μl of the sample solution, and the mixture was allowed to stand in a dark room for 2.5 minutes, and the absorbance was measured at 734 nm.

The results are shown in Tables 6 and 7 below.

Results of measurement of DPPH radical scavenging activity according to Test Example 1. Samples IC ₅₀
(mg.ml) Production Example 1 0.017 ± 0.00 Production Example 2 0.017 ± 0.00 Production Example 3 0.015 ± 0.00 Blueberries (dried) 0.627 + - 0.01 Red ginseng (6 years old, dried) 1.282 + 0.03

The IC ₅₀ value represents the concentration of the extract which reduces the value of the control without the extract by 50%. The smaller the IC ₅₀ value, the higher the antioxidant activity. Therefore, as shown in Table 6, DPPH radical scavenging activity measurement showed that the antioxidative ability of the nihiloya phalaenopsis was about 40 times higher than that of blueberry in all of Examples 1, 2 and 3 and about 75 times higher than that of red ginseng there was.

Results of measurement of ABTS radical scavenging activity according to Test Example 1. Samples IC ₅₀
(mg.ml) Production Example 1 0.070 ± 0.00 Production Example 2 0.071 ± 0.00 Production Example 3 0.067 ± 0.01 Blueberries 2.918 ± 0.13 Red ginseng 4.131 + 0.24

As shown in Table 7, according to the results of ABTS radical scavenging activity measurement, the antioxidative activity of the nifalia phalaenopsis was about 42 times higher than that of blueberries and about 59 times higher than that of red ginseng in Production Examples 1, 2 and 3 there was.

(Test Example 2)

Anti - Inflammatory Effects of.

The anti-inflammatory effect of the nifalgia phalaenopsis powder prepared in Preparation Example 1 was measured.

IL-1β (interleukin-1beta), IL-6 (interleukin-6, interleukin-6) and TNF-α (tumor necrosis factor-alpha, Or tumor necrosis factor-alpha).

The test method was to investigate whether inflammation was induced by macrophages using LPS (lipopolysaccharide) and the general inflammation index was suppressed when the sample was treated with LPS (lipopolysaccharide). As a positive control, DEX (Dexamethasone) was used as a comparative drug.

 The results are shown in Figs. 2 to 5. Fig.

As can be seen from FIG. 2, Nitrite was significantly increased upon induction of inflammation by LPS, but Nitrite, which was increased due to the treatment of Nephala palmaxil powder, was decreased.

As can be seen from FIGS. 3, 4 and 5, cytokine was significantly increased upon induction of inflammation caused by LPS, but it was confirmed that the inflammation was alleviated by treatment with the nifalaxy powder.

Therefore, it was judged that the powder of Nypaya japonica had an inhibitory effect on inflammatory factors in a concentration-dependent manner and a suppressive effect similar to that of DEX known as anti-inflammatory component.

(Example 1)

Animal feeds were prepared by mixing 1 kg of the nipahaya phalaenopsis powder of Preparation Example 1 and 99 kg of general compound feed.

(Example 2)

Animal feeds were prepared by blending 5 kg of the nipahaya phalaenopsis powder of Preparation Example 1 and 95 kg of a general compound feed.

(Example 3)

3 kg of the extract of Preparation Example 2 was further compounded in the same manner as in Example 1.

(Example 4)

3 kg of the extract of Preparation Example 3 was further compounded in the same manner as in Example 2.

(Comparative Example 1)

Only normal compound feed was used.

(Comparative Example 2)

An antibiotic mixed with avilamycin and salinomycin at a weight ratio of 1: 1 was added to a general compound feed, and the avilamycin and salinomycin were mixed by 200 ppm.

(Test Example 3)

Feed compositions prepared according to Examples 1 to 4 were fed to chickens of experimental groups 1, 2, 3 and 4, and feeds of the feeds of Comparative Examples 1 and 2 to chickens of control groups 1 and 2, respectively. Experimental groups 1, 2, 3 and 4 and control groups 1 and 2 each contained 200 sheep breeds of 16 - week - old laying hens. Feed intake, egg production rate and average weight of eggs were measured during 7 days of free feeding.

The results are shown in Table 8 below.

Test Example 3 Results. division Experiment 1 Experiment 2 Experiment group 3 Experiment group 4 Control 1 Control group 2 Daily dietary intake (g) 130.5 132.5 145.8 147.2 121.2 132.8 Egg production (%) 71.5 72.5 72.1 74.8 65.9 72.8 Average weight of 100 eggs (kg) 1.51 1.61 1.52 1.68 1.43 1.56

As shown in Table 8, the experimental groups 1, 2, 3 and 4 showed an increase in the feed intake, the egg production rate and the average weight of the eggs, compared with the control group 1, and were similar to those of the control group 2.

(Test Example 4)

Antioxidant enzyme - like activity (SOD like activity) was also measured to characterize antioxidant properties in blood. The results are shown in Table 9 below. The higher the level of these antioxidant enzymes, the stronger the antioxidant properties. As shown in Table 9 below, the levels of antioxidant enzymes were significantly higher in the experimental groups 1, 2, 3 and 4 than in the control groups 1 and 2, due to the antioxidant function of the phalaenopsis powder and extract .

Test Example 4 Results. division Experiment 1 Experiment 2 Experiment group 3 Experiment group 4 Control 1 Control group 2 Antioxidant enzyme activity (%) 21.07 22.08 21.22 22.52 19.31 19.87

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the scope of the present invention is not limited to the disclosed exemplary embodiments. It will also be appreciated that many modifications and variations will be apparent to those skilled in the art without departing from the scope of the invention.

Claims (7)

1. A feed composition comprising nipaya as an active ingredient, comprising a nipayanaya pedicel powder and a nipaya pedicel extract, wherein the nipaya pedis powder
A step of cutting a flower bud of nipaya,
Salting the cut flower stalk with a salinity of 8 to 12%
Aging the salted stalk for 40 to 60 hours,
Firstly dehydrating the aged flower buds,
Dewatering the primary dehydrated flower bed in water,
Secondly dehydrating the sea bed,
Adjusting the salinity of the secondary dehydrated flower bud to 0.3 to 0.8%
Drying the pedicel having the salinity adjusted,
The dried flower bud is prepared by pulverizing the flower bud to 200 to 300 mesh,
The fimbriae extract of Nipaya,
A step of cutting a flower bud of nipaya,
Extracting or ultrasonically extracting the cut flower of the nippae with water as a solvent,
Concentrating the extracted extract;
And lyophilizing the concentrated extract,
The phloem powder of nipahazja is contained in an amount of 1 to 5% by weight of the total feed composition,
Wherein the flower bud extract of Nipaya is contained in an amount of 1 to 5% by weight of the total feed composition. delete delete delete delete delete delete

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