KR101840825B1 - Manufacturing method for antibiotic coating layer of fiber, and antibiotic fiber manufactured by the same - Google Patents
Manufacturing method for antibiotic coating layer of fiber, and antibiotic fiber manufactured by the same Download PDFInfo
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- KR101840825B1 KR101840825B1 KR1020150190494A KR20150190494A KR101840825B1 KR 101840825 B1 KR101840825 B1 KR 101840825B1 KR 1020150190494 A KR1020150190494 A KR 1020150190494A KR 20150190494 A KR20150190494 A KR 20150190494A KR 101840825 B1 KR101840825 B1 KR 101840825B1
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- mixed solution
- coating layer
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- antimicrobial
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- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M13/00—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment
- D06M13/50—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment with organometallic compounds; with organic compounds containing boron, silicon, selenium or tellurium atoms
- D06M13/503—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment with organometallic compounds; with organic compounds containing boron, silicon, selenium or tellurium atoms without bond between a carbon atom and a metal or a boron, silicon, selenium or tellurium atom
- D06M13/507—Organic silicon compounds without carbon-silicon bond
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- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06B—TREATING TEXTILE MATERIALS USING LIQUIDS, GASES OR VAPOURS
- D06B3/00—Passing of textile materials through liquids, gases or vapours to effect treatment, e.g. washing, dyeing, bleaching, sizing, impregnating
- D06B3/10—Passing of textile materials through liquids, gases or vapours to effect treatment, e.g. washing, dyeing, bleaching, sizing, impregnating of fabrics
-
- D—TEXTILES; PAPER
- D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B2401/00—Physical properties
- D10B2401/13—Physical properties anti-allergenic or anti-bacterial
-
- D—TEXTILES; PAPER
- D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B2509/00—Medical; Hygiene
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- Engineering & Computer Science (AREA)
- Textile Engineering (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention relates to a method of forming an antimicrobial coating layer of a fiber using a silicate, and to an antibacterial fiber produced thereby. More specifically, a silica thin film bearing biorecein is prepared using TEOS and, finally, The present invention relates to a biomaterial immobilization technique for producing an antimicrobial fiber coated with a substance. According to the present invention, bio-lacein can be stably utilized in various textile fields by solving the problems of bio-lacein which was difficult to utilize due to the conventional hydrophobicity and stability.
Description
The present invention relates to a method of forming an antimicrobial coating layer of a fiber using a silicate, and to an antibacterial fiber produced thereby. More specifically, a silica thin film bearing biorecein is prepared using TEOS and, finally, The present invention relates to a biomaterial immobilization technique for producing an antimicrobial fiber coated with a substance. According to the present invention, bio-lacein can be stably utilized in various textile fields by solving the problems of bio-lacein which was difficult to utilize due to the conventional hydrophobicity and stability.
(Duran et al., 2004), anticancer activity (Kodach et al., 2006, Duran et al., 2007, Ferreira et al., 2004), which is a purple pigment produced from bacteria ), Antifungal (Becker et al., 2009), and anti-ulcer (Antonisamy et al., 2009).
In particular, bioraceae has a strong antimicrobial effect, such as showing antibacterial activity against a broad spectrum antibiotic-resistant bacterium called superbacteria, but it is very toxic to mammals (toxicity is not shown up to 40 mg / kg when oral administration to rats) It is very useful in medicine.
However, the bio-lacein is a very hydrophobic substance hardly dissolved in water and difficult to attach a support, so that it is difficult to apply it to various fields.
Accordingly, the object of the present invention is to solve the problems of bio-lacein which is difficult to utilize due to hydrophobicity and stability in spite of various effects and to provide a fiber which can be stably supported on a support, And an antimicrobial fiber produced by the method.
In order to achieve the above object, the present invention provides a method of manufacturing a semiconductor device, comprising the steps of: a) mixing tetraethyl orthosilicate (TEOS) with an alcohol, and then adding an acid to the mixed solution; b) aging the mixed solution to which the acid has been added, followed by aging at room temperature; c) adding and mixing a bioreceptor solution to the aged mixture; And d) coating the fiber surface with a mixed solution to which the biorecein solution is added. The present invention also provides a method for forming an antimicrobial coating layer on a fiber.
In one embodiment, the step a) of adding the acid to the mixed solution comprises: a-1) mixing tetraethyl orthosilicate and ethanol in a ratio of 1: 2 to 3; And a-2) stirring the mixed solution at room temperature for 10 to 30 minutes, and then injecting 0.1 M sulfuric acid by one drop. At this time, in step a-2), it is preferable to inject the 0.1 M sulfuric acid until the molar ratio of water becomes 1.5 to 2.5 times that of tetraethylorthosilicate.
In one embodiment, in the step b), the acid-added mixed solution is stirred for 1 to 3 hours and aged for 12 to 36 hours at room temperature.
In one embodiment, in step c), an ethanol solution in which bioracea is dissolved in an amount of 1 to 5 mg / ml is added to the aged mixed solution to increase the total mixed solution to 1.5 to 2.5 times.
In one embodiment, the step d) of coating the mixed solution on the surface of the fiber comprises: d) dipping the fiber in the d-1) mixed solution to form a coating liquid layer on the fiber surface; And d-2) drying the fiber having the coating liquid layer formed on the surface thereof to evaporate the solvent, and forming a silica thin film coating layer carrying bioraceane on the fiber surface.
On the other hand, the present invention provides a fiber having an antimicrobial coating layer formed on its surface by the above-described methods.
The antimicrobial fiber produced by the method of forming an antimicrobial coating layer of the present invention solves the problem of bio-lacein which was difficult to utilize due to the conventional hydrophobicity and stability, stably adheres to a support and the like while maintaining the functionality of bio- And can be used in various fields such as the stable.
FIG. 1 - Process conceptual diagram showing the process of forming a silica thin film coating layer carrying bioreceans of the embodiment
FIGS. 2 and 3 - photographs showing the surface of the fiber before and after the coating of the silica thin film on which bioerace
Hereinafter, preferred embodiments according to the present invention will be described in detail. Prior to the description, terms and words used in the present specification and claims should not be construed as limited to ordinary or dictionary terms and should be construed in a sense and concept consistent with the technical idea of the present invention.
Throughout this specification, when an element is referred to as "including" an element, it is understood that it may include other elements as well, without departing from the other elements unless specifically stated otherwise.
The method for forming an antimicrobial coating layer of a fiber according to the present invention is characterized in that a) an organic acid is mixed with tetraethyl orthosilicate (TEOS) and an alcohol in order to simplify the supporting process of biorecein while increasing the supporting efficiency, ; b) aging the mixed solution to which the acid has been added, followed by aging at room temperature; c) adding and mixing a bioreceptor solution to the aged mixture; And d) coating the fiber surface with a mixed solution to which the bioreceptor solution is added.
Let's take a closer look at each step below.
In order to form a silica thin film to serve as a carrier on the surface of a fiber, silica is synthesized by first mixing tetraethyl orthosilicate (TEOS) with alcohol and then adding acid to the mixed solution.
At this time, in order to improve the synthesis efficiency and the supporting efficiency of the silica carrier, the step (a) of synthesizing the silica carrier is a method in which the ratio of a-1) tetraethylososilicate and ethanol is 1: 2 to 3 ; And a-2) stirring the mixed solution at room temperature for 10 to 30 minutes, and then injecting 0.1 M sulfuric acid dropwise. In step a-2), the 0.1 M sulfuric acid is preferably injected until the molar ratio of water is 1.5 to 2.5 times that of tetraethylorthosilicate.
The acid-added mixed solution is agitated at room temperature after stirring to prepare a stable carrier. In a preferred embodiment, the acid-added mixed solution is agitated for 1 to 3 hours and then agitated at room temperature for 12 to 36 hours Can be aged for a while.
The aging-completed mixed solution is mixed with a bioracea solution to support an antimicrobial substance. In order to improve the bioreaction efficiency of the bioracea, the agar mixture is added with bioracea in an amount of 1 to 5 mg / ml It is preferable to increase the total amount of the mixed solution by 1.5 to 2.5 times and uniformly mix the solution.
After the mixing process, the bioracea solution is finally coated on the surface of the fiber. In this case, the step d) of coating the mixture on the surface of the fiber may be performed as follows. The fiber is immersed in the mixed solution to form a coating liquid layer on the surface of the fiber, the fiber having the coating liquid layer formed thereon is dried to evaporate the solvent, and the biolase is carried on the fiber surface through the reaction between the mixed liquid and the fiber surface A silica thin film coating layer can be formed.
In other words, in the step d), dipping the fibers in the d-1) mixed solution to form a coating liquid layer on the fiber surface; And d-2) drying the fiber having the coating liquid layer formed thereon to evaporate the solvent, and forming a silica thin film coating layer carrying bioraceane on the fiber surface.
In this way, it is possible to increase the amount of bioraceane to be supported while minimizing the loss of bioraceae, and it is also possible to easily coat the surface of the fiber with the bioracea carrier without any additional process using a separate binder, Can be easily manufactured.
Hereinafter, the effect of the present invention will be described in detail with reference to an embodiment of a method for forming an antibacterial coating layer of the fiber of the present invention. However, these embodiments are intended to illustrate one or more embodiments, and the scope of the invention is not limited to these embodiments.
[Example]
Bioreceans Preparation of fibers with antimicrobial coating layer containing
1) One mole of tetraethylososilicate was mixed with 2 moles of ethanol, stirred at room temperature for 10 minutes, and then 0.1 M sulfuric acid was added dropwise until the molar ratio of water was doubled to tetraethylososilicate. Thereafter, the mixture was stirred for 2 hours and aged at room temperature for 24 hours.
2) The ethanol solution dissolved in the concentration of 3 mg / ml of bioracea was injected into the aged mixed solution, and the whole mixed solution was doubled and mixed uniformly.
3) Fibers were immersed in the mixed solution to form a coating solution on the surface of the fibers, followed by drying, thereby finally forming a silica thin film coating layer bearing bioracea on the fiber surface. 2 and 3 are photographs showing the surface of the fiber before and after the bioraceane was carried, and it was confirmed that the surface of the fiber was coated with the silica thin film.
As can be seen from the above examples, the method of forming an antimicrobial coating layer of a fiber using TEOS of the present invention solves the problem of bio-lacein which was difficult to utilize due to the conventional hydrophobicity and stability, And can be utilized in various fields in a stable manner.
The present invention is not limited to the above-described specific embodiments and descriptions, and various modifications can be made to those skilled in the art without departing from the gist of the present invention claimed in the claims. And such modifications are within the scope of protection of the present invention.
Claims (3)
b) aging the mixed solution to which the acid has been added, followed by aging at room temperature;
c) adding and mixing a bioreceptor solution to the aged mixture; And
d) coating a mixed solution to which the bioracea solution is added on the fiber surface,
The step a)
a-1) mixing tetraethyl orthosilicate and ethanol at a ratio of 1: 2 to 3; And
a-2) stirring the mixed solution at room temperature for 10 to 30 minutes, and then injecting 0.1 M sulfuric acid dropwise.
D) coating the mixed solution on the surface of the fiber,
d-1) to form a coating liquid layer on the fiber surface; And
d-2) drying the fiber having the coating liquid layer formed on the surface thereof to evaporate the solvent, and forming a silica thin film coating layer carrying bioraceene on the fiber surface;
≪ / RTI > wherein the antimicrobial coating layer has a thickness of at least 10 microns.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020150190494A KR101840825B1 (en) | 2015-12-30 | 2015-12-30 | Manufacturing method for antibiotic coating layer of fiber, and antibiotic fiber manufactured by the same |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020150190494A KR101840825B1 (en) | 2015-12-30 | 2015-12-30 | Manufacturing method for antibiotic coating layer of fiber, and antibiotic fiber manufactured by the same |
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| Publication Number | Publication Date |
|---|---|
| KR20170079683A KR20170079683A (en) | 2017-07-10 |
| KR101840825B1 true KR101840825B1 (en) | 2018-03-22 |
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| KR1020150190494A KR101840825B1 (en) | 2015-12-30 | 2015-12-30 | Manufacturing method for antibiotic coating layer of fiber, and antibiotic fiber manufactured by the same |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101183544B1 (en) * | 2012-01-31 | 2012-09-20 | (주)케이피텍 | Preparation method of gas barrier coating liquid |
| KR101578372B1 (en) * | 2014-10-22 | 2015-12-21 | 한국세라믹기술원 | Violacein supported particle, and Manufacturing method of the same |
-
2015
- 2015-12-30 KR KR1020150190494A patent/KR101840825B1/en not_active Application Discontinuation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101183544B1 (en) * | 2012-01-31 | 2012-09-20 | (주)케이피텍 | Preparation method of gas barrier coating liquid |
| KR101578372B1 (en) * | 2014-10-22 | 2015-12-21 | 한국세라믹기술원 | Violacein supported particle, and Manufacturing method of the same |
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| Publication number | Publication date |
|---|---|
| KR20170079683A (en) | 2017-07-10 |
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