KR101753722B1 - Sample tray having easy vertical alignment - Google Patents

Sample tray having easy vertical alignment Download PDF

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Publication number
KR101753722B1
KR101753722B1 KR1020160006510A KR20160006510A KR101753722B1 KR 101753722 B1 KR101753722 B1 KR 101753722B1 KR 1020160006510 A KR1020160006510 A KR 1020160006510A KR 20160006510 A KR20160006510 A KR 20160006510A KR 101753722 B1 KR101753722 B1 KR 101753722B1
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KR
South Korea
Prior art keywords
cartridge
sample tray
support
wall
strip
Prior art date
Application number
KR1020160006510A
Other languages
Korean (ko)
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KR20170058815A (en
Inventor
홍세민
전성환
Original Assignee
(주)한울티피씨
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Publication of KR20170058815A publication Critical patent/KR20170058815A/en
Application granted granted Critical
Publication of KR101753722B1 publication Critical patent/KR101753722B1/en

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/06—Test-tube stands; Test-tube holders
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/023—Adapting objects or devices to another adapted for different sizes of tubes, tips or container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other

Abstract

The present invention relates to a sample tray in which vertical alignment of cartridges is easy. By forming a mounting wing on a cartridge and by forming a mounting groove on a support, the cartridge is firmly and securely fixed by mounting it on a support so that alignment is not broken.

Description

Sample tray having easy vertical alignment < RTI ID = 0.0 >

The present invention relates to a sample tray that is easily vertically aligned, and more particularly, by forming a mounting wing on a cartridge and by forming a mounting groove on a support, the cartridge is mounted on a support and fixed firmly and securely, To a sample tray.

The sample tray is equipped with a cartridge which accommodates a reagent, and a sample tray equipped with a reagent cartridge is mounted on a nucleic acid extraction equipment or the like. Since the conventional sample tray is inserted into a plurality of holes formed in the sample tray when the strip of the nucleic acid extraction equipment is inserted into a region where the cartridge is not mounted, if the diameter of the strip is changed or the position of the step is changed, The alignment or size of the hole becomes out of alignment. If the sample tray and the nucleic acid extraction equipment are used in a situation where it is not recognized, the sample tray may be broken or the alignment of the cartridges may be distorted, and the strip may be inclined to cause a problem in extracting the components of the reagent. Therefore, in order to mount a cartridge in the sample tray, various products can not be used universally, and the diameter of the strip and the insertion hole of the sample tray have to be always considered.

On the other hand, the prior art relating to the sample tray is the Korean Utility Model Registration No. 20-0473547.

Disclosure of Invention Technical Problem [8] Accordingly, the present invention has been made keeping in mind the above problems occurring in the prior art, and an object of the present invention is to provide a nucleic acid extracting apparatus for extracting nucleic acid, There is a purpose.

According to an aspect of the present invention, there is provided a sample tray, including: a cartridge having a plurality of solution receiving portions for containing a solution; A wall defining a space for mounting the cartridge by separating the cartridge from the outside by forming a circumference and a predetermined height; A plate provided at the lower end of the wall by connecting respective lateral sides of the wall; And a support formed on the upper surface of the plate to define a space in which the cartridge can be inserted.

At least one mounting blade is formed on the side surface of the cartridge, and a mounting groove is formed in the support or the wall, and the cartridge is inserted into the cartridge insertion portion formed between the supports or between the support and the wall, Is mounted by being inserted into the mounting groove.

The sample tray for easy vertical alignment is characterized in that only one of the cartridges is inserted into the cartridge inserting portion on the horizontal line.

Finally, the cartridge is provided with a solution accommodating portion in which a space is separated from each other, and an end of the solution accommodating portion is detachable and engageable with the cartridge, and a guide formed on a side surface of the cartridge and a And the guide grooves are combined with each other to facilitate alignment of the solution containing portion.

According to another aspect of the present invention, there is provided a sample tray, including: a cartridge having a plurality of solution receiving portions for containing a solution; The tip of the solution containing portion is separable and engageable with the guide, and the guide formed on the side surface of the cartridge and the guide groove formed in the solution containing portion are engaged when the cartridge is coupled.

The sample tray according to the present invention has the following effects.

First, various types of cartridges can be installed in nucleic acid extraction equipment. The sample tray according to the present invention has a structure in which the support table is formed on the upper surface of the plate forming the bottom of the sample tray and the cartridge is fixed by the support table so that there is no configuration for guiding the respective strips between the spaces in which the cartridges are mounted, And is formed as an empty space. Accordingly, even if the diameter of the strip and the stepwise movement position of the strip are changed, or the interval of the solution receiving part of the cartridge is changed, the strip can not be used against the sample tray during the up and down movement of the strip.

Second, the sample tray firmly supports the cartridge. Conventionally, since the sample tray supports the cartridge only over the upper hole and does not support the lower end, the cartridge may be screwed and vertical alignment may not be achieved. However, in the present invention, since the support and the mounting groove are formed for mounting the cartridge in the sample tray, the cartridge is firmly fixed to both the support and mounting grooves so that the vertical alignment at the time of mounting is maintained, Thus, nucleic acid extraction can be easily performed.

Third, the cartridge can be used efficiently. The cartridge containing the Bondy solution or the reagent is disposable, and there is a lot of waste in using it. However, since the sample tray according to the present invention is a form in which the cartridge is coupled to the cartridge inserting portion, the user can mount and use the required number of cartridges, so that the cartridge can be economically used without waste.

1 is a perspective view of a sample tray according to an embodiment of the present invention;
2 is a perspective view of a cartridge according to an embodiment of the present invention;
FIG. 3 is a perspective view of the sample tray and the cartridge shown in FIGS. 1 and 2 in combination. FIG.
Figure 4 is a bottom perspective view of the sample tray and cartridge shown in Figure 3;
Figure 5 is a top view of the sample tray and cartridge shown in Figure 3;
6 is a perspective view of a cartridge according to another embodiment of the present invention.
7 is an exploded perspective view of the cartridge shown in Fig.

Hereinafter, preferred embodiments of the present invention will be described with reference to the accompanying drawings. However, some configurations which are not related to the gist of the present invention may be omitted or compressed, but the configurations omitted are not necessarily those not necessary in the present invention, and they may be combined by a person having ordinary skill in the art to which the present invention belongs. .

FIG. 1 is a perspective view of a sample tray according to an embodiment of the present invention, FIG. 2 is a perspective view of a cartridge according to an embodiment of the present invention, FIG. 3 is a perspective view of a sample tray and a cartridge shown in FIGS. FIG. 4 is a bottom perspective view of the sample tray and cartridge shown in FIG. 3, FIG. 5 is a top view of the sample tray and cartridge shown in FIG. 3, FIG. 6 is a perspective view of a cartridge according to another embodiment of the present invention, 7 is an exploded perspective view of the cartridge shown in Fig.

As shown in FIGS. 1 to 7, a sample tray (hereinafter, referred to as a 'sample tray') that facilitates vertical alignment according to an embodiment of the present invention includes a wall 100 and a plate 120.

The wall 100 is a structure for providing a space in which the cartridge 20 can be mounted, and forms a square perimeter with a predetermined height. A wall mounting groove 110 is formed at one side of the wall 100 so that the cartridge 20 can be mounted on the wall 100. In addition, a tray support 111 is formed at a lower end of the wall 100 in an inclined form so that the sample tray 10 can be stably mounted on the ground.

The plate 120 connects the sides of the pedestal formed at the lower end of the wall 100. In the present invention, two plates 120 are formed. Ultimately, the cartridge 20 is mounted while being inserted into the plate 120. A support base 130, a cartridge insertion portion 140, and a heater mounting groove 150 are formed in the plate 120.

The support base 130 is a plate having a substantially U-shaped cross section on the upper surface of the plate 120, and the cartridge 20 is inserted between the support bases 130. That is, each support base 130 is formed at a distance that allows insertion of the cartridge 20, and a support base mounting groove 131 is formed on the side of the base 130 so that the cartridge 20 can be mounted. In addition, a reinforcing rib 132 is formed on the side of each support base 130 to the upper end of the support base 130 to vertically support the support base 130 so as not to collapse.

The cartridge inserting portion 140 is formed by inserting the cartridge 20 into the upper surface of the plate 120 and separating the two supports 130 from each other. The cartridge 20 is inserted into the space thus formed. The plurality of cartridge inserting portions 140 are spaced apart from each other, and the strip can move up and down when the nucleic acid extracting apparatus operates at an interval therebetween.

The heater mounting grooves 150 are formed on the bottom surface of the plate 120. In order to properly maintain the temperatures of the reagents and solutions contained in the cartridges 20, The heating section of the apparatus in which the heat is discharged to the heating section 150 is inserted.

Next, the cartridge 20 is mounted on the sample tray 10 to form a plurality of solution receiving portions 200 and mounting wings 210 as a tool for containing a solution and used for nucleic acid extraction of a solution.

The solution receiving portion 200 is a space for storing a solution, and the cartridge 20 has a plurality of solution receiving portions 200 formed therein. The diameter of the solution receiving portion 200 is formed to be sufficiently large enough to allow the strip to be inserted. Here, the strip is a constitution of a nucleic acid extracting apparatus, and performs a function of extracting nucleic acid from a reagent or a solution contained in the cartridge 20 or extracting it, and then mixing with another solution.

The mounting blade 210 is inserted into the wall mounting groove 110 formed in the support base mounting groove 131 or the wall 100 of the support base 130 to mount the cartridge 20, A large number of which are formed on the side surface.

Hereinafter, the structure of the sample tray 10 and the cartridge 20 will be described in detail with reference to the drawings. As shown in FIG. 3, the sample tray 10 according to the embodiment of the present invention has a predetermined height and forms a rectangular wall 100. The wall 100 may be regarded as a side surface of a hexahedron, and the sample tray 10 of the present invention has an open top and a bottom.

A tray support 111 is formed at the lower end of the wall 100 so that the sample tray 10 can be supported on the ground or the nucleic acid extracting apparatus. That is, the tray support 111 is formed at a lower end of the wall 100 so as to be inclined in the direction of the paper surface, so that the sample tray 10 can be securely placed on the ground or the nucleic acid extracting apparatus.

A plate 120 is formed at the lower end of the wall 100 so as to connect the sides of the wall 100 to form a support base 130. That is, a plurality of supports 130 are formed on the plate 120, and a support base 130 is formed, so that a cartridge inserting portion 140 is formed between the support bases 130 so that the cartridge 20 is inserted. A support bracket mounting groove 131 is formed at the upper end of the support bracket 130 so that the mounting blade 210 formed on the side surface of the cartridge 20 is inserted into the bracket mounting groove 131, So that it can be mounted in a state in which the vertical can be perfectly maintained.

A reinforcing rib 132 is formed between the support rods 130 so that the support rods 130 can be stably formed upright. The reinforcing ribs 132 are formed so as to intersect with each other in order to avoid overlapping of the supporting rods 130 facing each other, and the supporting rods mounting grooves 131 are also formed so as to intersect with each other.

A part of the wall 100 is formed with a wall mounting groove 110 that performs the same function as the support mounting groove 131 so that the cartridge 20 is inserted into the cartridge insertion portion 140). In the present invention, not only is it simply inserted into the sample tray 10 but also the side and the lower end of the cartridge 20 are fixed firmly to the support base 130, So that vertical alignment of the cartridge 20 is ensured. 5, when the cartridge 20 is mounted between the supports 130, the cartridge 20 is fixed by the support 130 so that the cartridge 20 is prevented from moving up or down, The cartridge 20 is prevented from moving or being heard from the left and right because the vertical alignment of the cartridges 20 in the vertical direction is ensured and the cartridges 20 are mounted in the support mounting grooves 131, And vertical alignment can be made perfectly.

The description of the distance between the mounted cartridges 20 will be continued with reference to Fig. In the present invention, the cartridges (20) are mounted on the two plates (120) crosswise rather than horizontally. That is, in the plate 120 on the left side, the cartridge inserting portion 140 is formed first by the wall 10 and the support 130 at the uppermost position in the plan view and then formed between the supports 130, The cartridge inserting portion 140 is formed below the left plate 120 and is then similarly formed between the supports 130. Therefore, each cartridge 20 can be easily mounted with a sufficient space on the horizontal line.

Further, the vertical alignment of the cartridge 20 is not broken by the strip inserted into the solution accommodating portion 200. The strips are repeatedly inserted and removed in the respective solution receiving portions 200 formed in the cartridge 20 while moving up and down. In the space where the cartridges 20 are not mounted, the strips will move up and down in the empty space. In the present invention, since a guide or a partition where the strip is positioned is not formed when the strip is lowered in the space between the cartridge inserting portions 140, even if the diameter of the strip is different, The contact between the sample tray 10 and the strip does not occur, and as a result, the vertical alignment of the cartridge 20 is not interrupted.

Alternatively, if a guide or partition is formed in the sample tray 10, when the diameter of the strip and the position of the stepwise movement are changed, the alignment of the guide or the partition and the strip does not coincide with each other. The sample tray 10 can be used regardless of the diameter or moving position of the strip because no guide or partition is formed in the sample tray 10 in the present invention .

Meanwhile, various types of cartridges 20 may be used for the sample tray 10 according to the present invention. That is, even if the size, distance, and number of the solution receiving portions 200 are different in the same size of the cartridge 20, the diameter of the plurality of solution receiving portions 200 is large enough to enable the strip to be inserted, It is possible to use it if it can be inserted into the cartridge inserting portion 140. Therefore, the cartridge 20 mentioned in the above description is one example.

6 and 7 show the cartridge b 30 as another example of such a cartridge 20. As shown in Fig. The cartridge b 30 is configured to have the mounting vane 310 similar to the cartridge 20, but it is possible to separate the solution receiving portion 300 at the end. That is, the solution in which the compounding is completed by the strip during the experiment is immersed in the solution containing portion 300 and separated, thereby facilitating storage. The solution receiving part 300 is provided with a film 320 which is fused with ultrasonic waves on its separated surface and is attached to the double-sided tape 330 so that it can be easily separated or combined if necessary. Since the guide groove 340 and the guide 350 are formed on the side surface of the cartridge 30, it is possible to accurately align the position to be engaged at the time of engagement. Finally, a cap 360 may be provided to prevent the solution from contacting the air and not to be accidentally lost by the user.

As described in detail above, the sample tray 10 according to the present invention can mount various types of cartridges 20 in the nucleic acid extraction equipment. The sample tray 10 according to the present invention has a structure in which the support table 130 is formed on the upper surface of the plate 120 forming the bottom of the sample tray 10 and the cartridge 20 is fixed by the support table 130 There is no configuration for guiding the respective strips between the spaces in which the cartridges 20 are mounted, and they are simply formed as empty spaces. Accordingly, even if the diameter of the strip and the moving position of the strip are changed or the separation distance between the cartridges 20 is changed, the strip can be used variously because the strip is not in contact with the sample tray 10 during the vertical movement of the strip.

In addition, the sample tray 10 firmly supports the cartridge 20. Conventionally, since the sample tray supports the cartridge only over the upper hole and does not support the lower end, the cartridge may be screwed and vertical alignment may not be achieved. However, in the present invention, since the support base 130 and the mounting grooves 110 and 131 are formed to mount the cartridge 20 to the sample tray 10, the cartridge 20 is supported by the support base 130 and the mounting grooves 110, 131 of the cartridge 20 are firmly fixed so as not to deviate from the initial position, the vertical alignment of the cartridge 20 is ensured and nucleic acid extraction is facilitated easily.

In addition, the cartridge 20 can be efficiently used. The cartridge 20 containing the main body solution or reagent is disposable, and there is a lot of room for waste in use. However, since the sample tray 10 according to the present invention has a structure in which the cartridge 20 is coupled to the cartridge inserting portion 140, the user can mount and use the required number of the cartridges 20, And can be used economically.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, And additions should be considered as falling within the scope of the claims of the present invention.

10: Sample tray
100: Wall
110: Wall mounting groove
111: tray base
120: Plate
130: Support
131: Support mounting groove
132: reinforcing rib
140: cartridge inserting portion
150: Heater mounting groove
20: Cartridge
200: solution receiving portion
210: mounting wing
30: Cartridge b
300: solution receiving portion
310: mounting wing
320: Film
330: Double-sided tape
340: guide groove
350: Guide
360: Plug

Claims (5)

1. A sample tray used in a nucleic acid extracting apparatus,
A cartridge in which a plurality of solution containing portions are contained;
A wall defining a space for mounting the cartridge by separating the cartridge from the outside by forming a circumference and a predetermined height;
A plate provided at the lower end of the wall by connecting respective lateral sides of the wall; And
And a support formed on the upper surface of the plate to define a space for inserting the cartridge,
At least one mounting blade is formed on a side surface of the cartridge,
A mounting groove is formed in at least a part of the support base and the wall,
Wherein the cartridge is mounted by inserting the mounting wing into the mounting groove in the cartridge inserting portion formed between the supporting rods or between the supporting rods and the wall,
In the plate on the left side, the cartridge inserting portion is formed first by the wall and the support on the uppermost plane in the plan view and then formed between the supports. On the right side plate, the cartridge inserting portion is formed below the left plate, By being formed between the supports, the cartridges are mounted crosswise transversely,
The cartridge is formed with a solution containing portion in which a space is separated from each other,
And a guide formed on a side surface of the cartridge and a guide groove formed in the solution containing portion are engaged with each other when the cartridge is coupled,
Wherein the support is formed on the upper surface of the plate and the cartridge is fixed by the support to form a space between the spaces in which the cartridge is mounted so that the diameter of the strip and the stepwise movement position of the strip are changed, Wherein the strip is not in contact with the sample tray during the vertical movement of the strip, so that the sample tray can be used in various ways. delete delete delete delete
KR1020160006510A 2015-11-19 2016-01-19 Sample tray having easy vertical alignment KR101753722B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20150162599 2015-11-19
KR1020150162599 2015-11-19

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KR20170058815A KR20170058815A (en) 2017-05-29
KR101753722B1 true KR101753722B1 (en) 2017-07-04

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190033331A (en) * 2017-09-21 2019-03-29 (주)오상헬스케어 Well plate adjustable for a number of wells
CN111495444A (en) * 2019-01-30 2020-08-07 台湾圆点奈米技术股份有限公司 Combined reagent disk and reagent tank set

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001508862A (en) * 1996-07-03 2001-07-03 ベックマン コールター インコーポレイテッド Reagent cartridge
JP2004313887A (en) * 2003-04-14 2004-11-11 Aloka Co Ltd Thermostat

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001508862A (en) * 1996-07-03 2001-07-03 ベックマン コールター インコーポレイテッド Reagent cartridge
JP2004313887A (en) * 2003-04-14 2004-11-11 Aloka Co Ltd Thermostat

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190033331A (en) * 2017-09-21 2019-03-29 (주)오상헬스케어 Well plate adjustable for a number of wells
KR101984079B1 (en) 2017-09-21 2019-06-04 (주)오상헬스케어 Well plate adjustable for a number of wells
CN111495444A (en) * 2019-01-30 2020-08-07 台湾圆点奈米技术股份有限公司 Combined reagent disk and reagent tank set

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