KR101697866B1 - Two phase extraction apparatus and system for production of organic acid including the same - Google Patents

Two phase extraction apparatus and system for production of organic acid including the same Download PDF

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KR101697866B1
KR101697866B1 KR1020150064748A KR20150064748A KR101697866B1 KR 101697866 B1 KR101697866 B1 KR 101697866B1 KR 1020150064748 A KR1020150064748 A KR 1020150064748A KR 20150064748 A KR20150064748 A KR 20150064748A KR 101697866 B1 KR101697866 B1 KR 101697866B1
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organic acid
extraction solvent
path
path plate
fermentation reaction
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KR20160131743A (en
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이태호
상병인
전재성
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한양대학교 산학협력단
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/20—Degassing; Venting; Bubble traps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/24—Recirculation of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH

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Abstract

The present invention relates to an abnormal extractor and an organic acid production system including the same, which comprises a housing container and an upper lid; At least one supply pipe provided on one side of the upper surface of the housing vessel for injecting the fermentation reaction liquid; At least one first path plate provided inside the housing container in correspondence with the supply pipe; At least one second path plate provided in the housing vessel in a downward direction corresponding to the first path plate; An extraction solvent inlet for injecting an extraction solvent into a lower side of the housing vessel; An extraction solvent outlet for discharging an extraction solvent extracting organic acid from the other side of the upper surface of the housing vessel; And a drain valve for discharging the fermentation reaction solution from which the organic acid has been extracted to the other side of the lower surface of the housing container, and an organic acid production system including the same.
According to the present invention, by using an ideal extractor for extracting organic acid in a process of passing through a natural convection path due to the specific gravity difference, emulsion phenomenon which is a suspension which can not be easily separated and recovered by mixing a conventional fermentation reaction solution and extraction solvent And extraction efficiency of the organic acid and extraction reliability can be improved.

Description

TECHNICAL FIELD The present invention relates to a two-phase extraction apparatus and an organic acid production system including the same,

The present invention relates to an abnormal extractor and an organic acid production system including the same. More particularly, the present invention relates to an abnormal extractor that prevents emulsion and continuously extracts the organic acid using a specific gravity difference, and an organic acid production system including the same.

The term "organic acid fermentation by microorganism" refers to a process for producing various organic acids by incomplete oxidation of a carbon compound through a fermentation reaction by a microorganism. By using the fermentation reaction of such microorganisms, various organic acids such as acetic acid, propionic acid, butyric acid, Or alcohol-based compounds such as butanol.

The organic acids or alcohols thus produced can be used as platform chemicals in various chemical processes and can be used to synthesize materials with higher value through subsequent catalytic processes.

At this time, the organic acid produced by the fermentation reaction of the microorganism is extracted using an organic solvent or the like. Conventionally, a two phase extraction method is used. Such an ideal extraction method is characterized in that the amount of the organic solvent for extraction is increased or the interface area is increased by strong stirring.

However, such a conventional anomaly extraction method has a problem in that it causes non-economical efficiency and environmental pollution increase due to an increase in use of solvent and emulsion which can not be easily separated and recovered in an organic acid extraction process.

Patent Document: Japanese Patent Application Laid-Open No. 10-1199446

The present invention has been made in order to solve the above problems, and an object of the present invention is to provide an abnormality extractor for preventing emulsion and continuously extracting organic acids by using a specific gravity difference.

Another object of the present invention is to provide an organic acid production system including an ideal extractor for preventing emulsion and continuously extracting organic acids using specific gravity difference.

According to the present invention,

A housing vessel and an upper lid;

At least one supply pipe provided on one side of the upper surface of the housing vessel for injecting the fermentation reaction liquid;

At least one first path plate provided inside the housing container in correspondence with the supply pipe;

At least one second path plate provided in the housing vessel in a downward direction corresponding to the first path plate;

An extraction solvent inlet for injecting an extraction solvent into a lower side of the housing vessel;

An extraction solvent outlet for discharging an extraction solvent extracting organic acid from the other side of the upper surface of the housing vessel; And

A drain valve for discharging the fermentation reaction liquid from which the organic acid has been extracted on the other lower surface of the housing container;

.

According to an embodiment of the present invention, the other side of the supply pipe may be inserted into the housing container, the other end may form a clogged pipe, and may have a plurality of injection holes along the longitudinal direction.

According to another embodiment of the present invention, the first path plate has the same plate shape as the inner end surface of the housing container, the first path plate has a plurality of first inflow holes arranged in the middle area, The first path structure may be provided.

According to another embodiment of the present invention, the second path plate has the same plate shape as the inner end surface of the housing container, and a plurality of second inflow holes are arranged in the middle area, and the first path structure overlaps with the first path structure The second path structure may be provided at the other end.

According to another embodiment of the present invention, the first path structure may be provided in a cylindrical shape passing through the first path plate.

According to another embodiment of the present invention, the second path structure may be provided in a cylindrical shape passing through the second path plate.

According to another embodiment of the present invention, the fermentation reaction liquid injected through the supply pipe flows down the inner side of the first path structure along the first path plate, and flows along the second path plate to the second path structure And flows along the other first path plate to the inside of the first path structure and can be discharged through a path leading to the drain valve.

According to another embodiment of the present invention, the extraction solvent injected through the extraction solvent inlet may flow through the first inlet hole of the first path plate and the second inlet hole of the second path plate to the extraction solvent outlet Lt; / RTI >

Further, the present invention provides an organic acid production system, wherein the organic acid production system according to the present invention comprises:

An organic acid production fermenter containing therein a microorganism and a culture medium for performing organic acid fermentation;

A separator for filtering the microorganisms from the fermentation reaction liquid generated in the organic acid production fermenter and returning the microorganisms to the organic acid production fermenter;

A reservoir for storing the fermentation reaction solution treated from the separator;

A pH is increased between the organic acid production fermenter and the storage to lower the pH of the fermentation reaction solution stored in the storage;

An anomaly extractor connected to the reservoir and forming a plurality of flow pathways and extracting organic acids from the fermentation reaction solution using an extraction solvent by a two phase extraction method using a specific gravity difference;

A first extraction solvent reservoir for supplying the extraction solvent to the abnormal extractor;

A second extraction solvent reservoir for storing an extraction solvent extracting the organic acid discharged from the abnormal extractor; And

Wherein the pH of the fermentation reaction liquid discharged from the abnormal extractor is raised to be returned to the organic acid production fermenter

.

According to an embodiment of the present invention, the carbon dioxide gas generated in the organic acid producing fermenter for increasing the pH may be injected into the fermentation reaction solution stored in the reservoir.

According to another embodiment of the present invention,

A housing vessel and an upper lid;

At least one supply pipe provided on one side of the upper surface of the housing vessel for injecting the fermentation reaction liquid;

At least one first path plate provided inside the housing container in correspondence with the supply pipe;

At least one second path plate provided in the housing vessel in a downward direction corresponding to the first path plate;

An extraction solvent inlet for injecting an extraction solvent into a lower side of the housing vessel;

An extraction solvent outlet for discharging an extraction solvent extracting organic acid from the other side of the upper surface of the housing vessel; And

A drain valve for discharging the fermentation reaction liquid from which the organic acid has been extracted on the other lower surface of the housing container;

. ≪ / RTI >

According to another embodiment of the present invention, the other side of the supply pipe may be inserted into the housing container, the other end may form a clogged pipe, and may have a plurality of injection holes along the longitudinal direction.

According to another embodiment of the present invention, the first path plate has the same plate shape as the inner end surface of the housing container, and a plurality of first inflow holes are arranged in the middle area, and one side And the first path structure may be provided at the end portion.

According to another embodiment of the present invention, the second path plate has the same plate shape as the inner end surface of the housing container, and a plurality of second inflow holes are arranged in the middle area, and the first path structure overlaps with the first path structure The second path structure may be provided at the other end.

According to another embodiment of the present invention, each of the first path structure and the second path structure may be provided in a cylindrical shape passing through the first path plate and the second path plate, respectively.

According to another embodiment of the present invention, the extraction solvent extracted from the organic acid stored in the second extraction solvent reservoir may be transferred to the first extraction solvent reservoir after the organic acid is separated.

According to another embodiment of the present invention, the degassing vessel may degas the carbon dioxide at a pressure of 100 mmHg to 760 mmHg and a temperature of 20 to 30 ° C for the fermentation reaction liquid.

The features and advantages of the present invention will become more apparent from the following detailed description based on the accompanying drawings.

Prior to this, terms and words used in the present specification and claims should not be construed in a conventional, dictionary sense, and should not be construed as defining the concept of a term appropriately in order to describe the inventor in his or her best way. It should be construed in accordance with the meaning and concept consistent with the technical idea of the present invention.

According to the present invention, by using an ideal extractor for extracting organic acid in a process of passing through a natural convection path due to the specific gravity difference, emulsion phenomenon which is a suspension which can not be easily separated and recovered by mixing a conventional fermentation reaction solution and extraction solvent And extraction efficiency of the organic acid and extraction reliability can be improved.

1 is a block diagram of an organic acid production system according to an embodiment of the present invention.
FIG. 2A is an exploded perspective view of the abnormal extractor shown in FIG. 1. FIG.
2B is a sectional view of the abnormal extractor shown in FIG.
3 is a diagram illustrating an operation example of the abnormal extractor shown in FIG.

BRIEF DESCRIPTION OF THE DRAWINGS The objects, particular advantages and novel features of the present invention will become more apparent from the following detailed description taken in conjunction with the accompanying drawings, in which: FIG. It should be noted that, in the present specification, the reference numerals are added to the constituent elements of the drawings, and the same constituent elements are assigned the same number as much as possible even if they are displayed on different drawings. Also, the terms first, second, etc. may be used to describe various components, but the components should not be limited by the terms. The terms are used only for the purpose of distinguishing one component from another. In the following description, well-known functions or constructions are not described in detail since they would obscure the invention in unnecessary detail.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. FIG. 1 is a block diagram of an organic acid production system according to an embodiment of the present invention, FIG. 2 is an exploded perspective view of the ideal extractor shown in FIG. 1, FIG. 2 b is a sectional view of the ideal extractor shown in FIG. 1 is a diagram illustrating an operation example of the abnormal extractor shown in FIG. 1. FIG.

The organic acid production system according to an embodiment of the present invention shown in FIG. 1 includes an organic acid production fermenter 110, a separator 120, a reservoir 130, an ideal extractor 140, a pH- A second extraction solvent reservoir 170, and a degassing vessel 180. The first extraction solvent reservoir 170 may be a first extraction solvent reservoir.

Specifically, the organic acid production fermenter 110 receives a microorganism and a microorganism culture liquid for performing organic acid fermentation therein, and produces a fermentation broth as a result of a fermentation reaction with the microorganism. The organic acid producing fermenter 110 may produce various organic acids selected from the group consisting of butyric acid, hexanoic acid, and mixtures thereof. At this time, it is possible to use any one of organic acid producing microorganisms known in the art for the production of various organic acids, but it is also possible to use a mixture of such organic acid producing microorganisms.

The separator 120 separates only the microorganisms from the mixture of the microorganism performing the organic acid fermentation by the MBR (Membrane Bio Reactor) method and the fermentation broth, which is the result of the fermentation reaction performed by the microorganism, As shown in Fig. The separator 120 may include, for example, a ceramic material film or a polymer material film in which micropores having a diameter of 0.2 mu m to 0.5 mu m are formed.

The separator 120 functions to adjust the pH of the fermentation reaction liquid generated in the organic acid production fermenter 110. That is, as the fermentation process of the microorganism proceeds in the organic acid production fermenter 110, the produced organic acid is accumulated in the organic acid production fermenter 110 and the pH of the fermentation reaction solution is lowered by increasing the concentration of organic acid in the fermentation reaction liquid. This lowered pH is a factor for inhibiting the fermentation reaction of microorganisms. Therefore, in order to prevent the pH of the fermentation reaction solution from lowering, the microorganisms are filtered from the fermentation reaction solution to return the microorganisms to the organic acid production fermenter 110, and the fermentation reaction solution obtained by filtering the microorganisms is separated.

The storage 130 is a device for storing a fermentation reaction solution obtained by filtering a microorganism through a separator 120. The pH of the fermentation reaction solution obtained by filtering the microorganism using the pH increasing 150 for extracting organic acid is lowered And the fermentation reaction solution.

In particular, the low pH is a factor that facilitates the extraction reaction by the extraction solvent in the organic acid extraction process performed in the extruder 140. To this end, rather than adding a separate pH-lowering agent to the fermentation reaction solution, the pH-raising unit 150 may inject the carbon dioxide gas generated from the fermentation reaction in the organic acid production fermenter 110 into the fermentation reaction solution stored in the reservoir 130 .

Accordingly, the carbon dioxide produced in the fermentation reaction can be effectively recycled for lowering the pH of the fermentation reaction solution stored in the reservoir 130, and the pH of the fermentation reaction solution injected with carbon dioxide can be lowered to a range of 4 to 5. This pH range is a very favorable numerical range for extracting the target organic acid from the fermentation reaction solution by using the extraction solvent in the extruder 140.

The pH drop using the pH raising 150 can be performed by bringing the carbon dioxide gas produced in the organic acid producing fermenter 110 into vapor-liquid contact with the fermentation reaction liquid stored in the reservoir 130, , The pH of the fermentation reaction solution is lowered. For example, the gas-liquid contact may be carried out by contacting the carbon dioxide gas produced in the organic acid producing fermenter 110 with a gas containing carbon dioxide gas, which is stored in the reservoir 130 for 10 minutes to 20 minutes at a pressure of 5 bar to 50 bar and a temperature of 4 ° C to 40 ° C With the fermentation reaction liquid under agitation conditions of 500 rpm or less.

As shown in FIGS. 2A and 2B, the abnormality extractor 140 is a device for extracting organic acids by forming a plurality of pathways using a two phase extraction method. At least one supply pipe 142 provided at the center of the upper side of the housing vessel 141 and at least one first branch pipe 142 provided corresponding to the supply pipe 142 in the housing vessel 141, A path plate 143 and at least one second path plate 144 provided in the housing vessel 141 in the downward direction corresponding to the first path plate 143. Here, the housing container 141 is shown in a hexahedron form in FIGS. 2A and 2B, but is not limited thereto and may be provided in various polygonal sectional shapes such as a cylindrical shape.

Specifically, the housing container 141 has an insertion hole into which a supply pipe 142 is inserted, and at least one first path plate 143 and a second path plate 144 are mounted 141-4, and 141-5 are provided in accordance with the number of the first path plate 143 and the second path plate 144. As shown in FIG. The housing container 141 is provided with an extraction solvent inlet 145 for injecting an extraction solvent into a lower side of the housing 141 and an extraction solvent outlet 146 for discharging an extraction solvent from which organic acid is extracted, And a drain valve 147 for discharging the fermentation reaction liquid in which the organic acid is extracted from the other side surface.

The supply pipe 142 is provided with a plurality of injection holes 142-1 along the longitudinal direction in the form of a tube inserted into the housing vessel 141 and closed at the other end inward of the housing vessel 141. Here, the supply pipe 142 is shown as one circular tube shape in FIGS. 2A and 2B, but it is not limited thereto, and a large number of pipes having various cross sections such as a rectangular pipe shape can be provided.

The first path plate 143 is a member having the same plate shape as the inner end surface of the housing vessel 141. The first path plate 143 has a plurality of first inlet holes 143-1 arranged in an intermediate region, The first path structure 143-2 is provided at one end of the first path structure 143-2.

The second path plate 144 has a plurality of second inflow holes 144-1 arranged in the middle area similar to the first path plate 143 so as not to overlap with the first path structure 143-2 And a second path structure 144-2 at the other end.

The plurality of first inlet holes 143-1 and the second inlet holes 144-1 provided in the first path plate 143 and the second path plate 144 are connected to a path through which the extraction solvent And the number and diameter can be set according to the flow rate of the extraction solvent.

Although the first path plate 143 and the second path plate 144 have a similar structure, the first path structure 143-2 and the second path structure 144-2 are provided at opposite ends, respectively . At this time, the first path structure 143-2 and the second path structure 144-2 are formed in a cylindrical shape passing through the first path plate 143 and the second path plate 144 in FIGS. 2A and 2B And may be provided in various tubular shapes such as a rectangular tubular shape in addition to a cylindrical shape.

As shown in FIG. 2B, the first path plate 143 and the second path plate 144 are separated from each other in the interior of the housing container 141 and are supported by the engaging shoulders 141-3, 141-4, And in particular, the first path structure 143-2 and the second path structure 144-2 are staggered with each other.

Accordingly, a plurality of paths can be formed with the first path plate 143 and the second path plate 144 as a boundary. That is, as shown in FIG. 3, the fermentation reaction liquid injected through the supply pipe 142 flows along the first path plate 143 because the specific gravity is relatively high, and flows downwardly inside the first path structure 143-2 And then flows along the second path plate 144 and flows inward and downward in the second path structure 144-2 and then flows along the other first path plate 143 to flow downward in the first path structure 143-2 And can be discharged through the "A" path leading to the drain valve 147.

On the other hand, since the extraction solvent injected through the extraction solvent inlet 145 is relatively low in specific gravity, the first inlet hole 143-1 of the first path plate 143 and the second inlet plate 143-1 of the second path plate 144 B "path leading to the extraction solvent outlet 146 via the inlet hole 144-1. Here, the extraction solvent may be selected from, for example, butyl butylate, dodecanol, oleyl alcohol, and mixtures thereof.

Of course, the first path plate 143 and the second path plate 144 may be additionally provided in the ideal extender 140 to form a longer path in addition to the "A" path and the "B" path shown in FIG. 3 .

By this route, the fermentation reaction liquid injected through the supply pipe 142 and the extraction solvent injected through the extraction solvent inlet 145 increase the interfacial area with each other and flow, and the mechanism of extracting the organic acid from the fermentation reaction liquid .

At this time, since the organic acid is extracted in the process of passing through the natural convection path by the specific gravity difference such as the "A" path and the "B" path, which is not an artificial stirring convention in the past, the conventional fermentation reaction liquid and the extraction solvent can be easily separated, It is possible to prevent the emulsion phenomenon as a suspension which can not be recovered.

The extraction solvent introduced into the extraction solvent inlet 145 of the abnormal extractor 140 is introduced from the first extraction solvent reservoir 160. The extracted extraction solvent is subjected to an organic acid extraction process in the abnormal extractor 140, And the extracted extraction solvent is transferred to the second extraction solvent reservoir 170. The extraction solvent stored in the second extraction solvent reservoir 170 is separated from the organic acid . ≪ / RTI > Therefore, the organic acid is separated from the extraction solvent through a separate catalytic process, and then the extraction solvent in which the organic acid is separated is transferred to the first extraction solvent reservoir 160 again.

The degassing vessel 180 performs a function of raising the pH of the fermentation reaction liquid in which the organic acid is extracted in the middle of feeding the fermentation reaction liquid from which the organic acid has been extracted to the organic acid production fermentation vessel 110 by the abnormality extractor 140. As described above, since the fermentation broth having a low pH inhibits the fermentation by the microorganisms, the pH of the fermentation reaction solution in which the organic acid is extracted before the fermentation reaction liquid in which the organic acid is extracted is returned to the organic acid production fermenter 110 Should rise.

For this purpose, the carbon dioxide is deaerated from the fermentation reaction liquid in which the organic acid has been extracted in the degassing tank 180. For example, when a pressure of 100 mmHg to 760 mmHg and a temperature condition of 20 to 30 ° C are applied to the fermentation reaction liquid, Degassing can be performed. The pH of the fermentation reaction liquid in which carbon dioxide has been degassed in the degassing vessel 180 is converted into 5.5 to 6.5 and can be returned to the organic acid production fermenter 110.

Therefore, in the organic acid production system according to the embodiment of the present invention, the microorganisms and the fermentation reaction solution are separated and the microorganisms are returned to the organic acid production fermenter 110. The fermentation reaction solution is further reduced in pH for extracting organic acids, 140, and the pH is further raised in the degassing vessel 180 and returned to the organic acid production fermenter 110.

Particularly, in the organic acid production system according to the embodiment of the present invention, the conventional fermentation reaction liquid and the extraction solvent are easily mixed and separated using the abnormal extractor 140 for extracting the organic acid in the process of passing through the natural convection path due to the specific gravity difference , It is possible to prevent the emulsion phenomenon to be a suspension which can not be recovered, so that the extraction efficiency of the organic acid and the extraction reliability can be improved.

Although the technical idea of the present invention has been specifically described according to the above preferred embodiments, it is to be noted that the above-described embodiments are intended to be illustrative and not restrictive.

It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit and scope of the invention.

110: organic acid production fermenter 120: separator
130: storage device 140: abnormal extractor
141: housing container 141-2: upper lid
141-3, 141-4, 141-5:
142: supply pipe 142-1: injection hole
143: first path plate 143-1: first inflow hole
143-2: First path structure 144: Second path plate
144-1: second inflow hole 144-2: second path structure
145: extraction solvent inlet 146: extraction solvent outlet
147: Drain valve 150: Strong pH
160: first extraction solvent reservoir 170: second extraction solvent reservoir
180:

Claims (17)

A housing vessel and an upper lid;
At least one supply pipe provided on one side of the upper surface of the housing vessel for injecting the fermentation reaction liquid;
At least one first path plate provided inside the housing container in correspondence with the supply pipe;
At least one second path plate provided in the housing vessel in a downward direction corresponding to the first path plate;
An extraction solvent inlet for injecting an extraction solvent into a lower side of the housing vessel;
An extraction solvent outlet for discharging an extraction solvent extracting organic acid from the other side of the upper surface of the housing vessel; And
A drain valve for discharging the fermentation reaction solution from which the organic acid has been extracted to the other lower surface of the housing container;
Lt; / RTI >
Wherein the other side of the supply pipe is inserted into the housing vessel and the other end of the supply pipe is in the form of a clogged tube and has a plurality of injection holes along the longitudinal direction,
Wherein the first path plate has the same plate shape as the inner end surface of the housing container and has a plurality of first inflow holes arranged in an intermediate region and has a first path structure at one end portion which is not overlapped with the supply pipe,
Wherein the second path plate has the same plate shape as the inner end surface of the housing container and has a plurality of second inflow holes arranged in an intermediate region and a second path structure at the other end portion that does not overlap with the first path structure And a second path plate disposed below the first path plate,
Wherein the fermentation reaction liquid injected through the injection hole moves in the first direction along the first path plate and after passing through the first path structure, Moving in a second direction, passing through the second path structure,
Wherein the extraction solvent has a relatively low specific gravity as compared with the fermentation reaction liquid and is sequentially discharged through the second inlet hole and the first inlet hole. delete delete delete The abnormal extractor according to claim 1, wherein the first path structure is provided in a tubular form passing through the first path plate. The abnormal extractor according to claim 1, wherein the second path structure is provided in a tubular form passing through the second path plate. The fermentation reaction liquid according to claim 1, wherein the fermentation reaction liquid injected through the supply pipe flows down the inner side of the first path structure along the first path plate and flows downward along the second path plate toward the inner side of the second path structure Flows along the other first path plate to the inside of the first path structure, and is discharged through a path leading to the drain valve. The method according to claim 1, wherein the extraction solvent injected through the extraction solvent inlet is discharged through a first inlet hole of the first path plate and a second inlet hole of the second path plate to the extraction solvent outlet Wherein the abnormal extractor comprises: An organic acid production fermenter containing therein a microorganism and a culture medium for performing organic acid fermentation;
A separator for filtering the microorganisms from the fermentation reaction liquid generated in the organic acid production fermenter and returning the microorganisms to the organic acid production fermenter;
A reservoir for storing the fermentation reaction solution treated from the separator;
A pH is increased between the organic acid production fermenter and the storage to lower the pH of the fermentation reaction solution stored in the storage;
An anomaly extractor connected to the reservoir and forming a plurality of flow pathways and extracting organic acids from the fermentation reaction solution using an extraction solvent by a two phase extraction method using a specific gravity difference;
A first extraction solvent reservoir for supplying the extraction solvent to the abnormal extractor;
A second extraction solvent reservoir for storing an extraction solvent extracting the organic acid discharged from the abnormal extractor; And
A degassing vessel for raising the pH of the fermentation reaction liquid discharged from the abnormal extractor and returning the pH to the organic acid production fermenter;
Lt; / RTI >
The abnormal extractor
A housing vessel and an upper lid;
At least one supply pipe provided on one side of the upper surface of the housing vessel for injecting the fermentation reaction liquid;
At least one first path plate provided inside the housing container in correspondence with the supply pipe;
At least one second path plate provided in the housing vessel in a downward direction corresponding to the first path plate;
An extraction solvent inlet for injecting an extraction solvent into a lower side of the housing vessel;
An extraction solvent outlet for discharging an extraction solvent extracting organic acid from the other side of the upper surface of the housing vessel; And
A drain valve for discharging the fermentation reaction solution from which the organic acid has been extracted to the other lower surface of the housing container;
/ RTI >
Wherein the other side of the supply pipe is inserted into the housing vessel and the other end of the supply tube is in the form of a clogged tube and has a plurality of injection holes along the longitudinal direction,
Wherein the first path plate has the same plate shape as the inner end surface of the housing container and has a plurality of first inflow holes arranged in an intermediate region and has a first path structure at one end portion which is not overlapped with the supply pipe,
Wherein the second path plate has the same plate shape as the inner end surface of the housing container and has a plurality of second inflow holes arranged in an intermediate region and a second path structure at the other end portion that does not overlap with the first path structure And a second path plate disposed below the first path plate,
Wherein the fermentation reaction liquid injected through the injection hole moves in a first direction along the first path plate and after passing through the first path structure, Moving in a second direction, passing through the second path structure,
Wherein the extraction solvent has a lower specific gravity than that of the fermentation reaction liquid and is sequentially passed through the second inlet hole and the first inlet hole to be discharged. The organic acid production system according to claim 9, wherein the carbon dioxide gas generated in the organic acid production fermenter is injected into the fermentation reaction solution stored in the reservoir. delete delete delete delete The organic acid production system according to claim 9, wherein each of the first path structure and the second path structure is provided in a tubular form passing through the first path plate and the second path plate. The organic acid production system according to claim 9, wherein the extraction solvent extracted from the organic acid stored in the second extraction solvent reservoir is transferred to the first extraction solvent reservoir after the organic acid is separated. 10. The organic acid production system according to claim 9, wherein the degassing vessel is configured to degas the carbon dioxide at a pressure of 100 mmHg to 760 mmHg and a temperature of 20 to 30 DEG C relative to the fermentation reaction liquid.
KR1020150064748A 2015-05-08 2015-05-08 Two phase extraction apparatus and system for production of organic acid including the same KR101697866B1 (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100329019B1 (en) * 1999-04-13 2002-03-18 윤덕용 Method for Manufacturing Organic Acid by High-Efficiency Fermentation
KR101314336B1 (en) * 2011-08-18 2013-10-14 장희현 Anaerobic Digestion System

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Publication number Priority date Publication date Assignee Title
CN1110341C (en) * 1995-10-19 2003-06-04 拜尔公司 Multiple phase extractor
KR101244469B1 (en) * 2010-04-19 2013-03-18 김성천 Method and Device for Producing Bio-Diesel and Fermentation Material by Culturing Microalgae
KR101199446B1 (en) 2011-04-08 2012-11-09 주식회사 한강엔지니어링 Extraction and fermentation apparatus of Continuous type

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100329019B1 (en) * 1999-04-13 2002-03-18 윤덕용 Method for Manufacturing Organic Acid by High-Efficiency Fermentation
KR101314336B1 (en) * 2011-08-18 2013-10-14 장희현 Anaerobic Digestion System

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