KR101675865B1 - Safety filter, manufacturing method and syringe having the same - Google Patents

Safety filter, manufacturing method and syringe having the same Download PDF

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Publication number
KR101675865B1
KR101675865B1 KR1020150088984A KR20150088984A KR101675865B1 KR 101675865 B1 KR101675865 B1 KR 101675865B1 KR 1020150088984 A KR1020150088984 A KR 1020150088984A KR 20150088984 A KR20150088984 A KR 20150088984A KR 101675865 B1 KR101675865 B1 KR 101675865B1
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KR
South Korea
Prior art keywords
filter
tube
needle
filter member
hub
Prior art date
Application number
KR1020150088984A
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Korean (ko)
Inventor
이재영
임현철
황원철
Original Assignee
주식회사 아모라이프사이언스
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 주식회사 아모라이프사이언스 filed Critical 주식회사 아모라이프사이언스
Priority to KR1020150088984A priority Critical patent/KR101675865B1/en
Priority to PCT/KR2016/006530 priority patent/WO2016208922A1/en
Application granted granted Critical
Publication of KR101675865B1 publication Critical patent/KR101675865B1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3145—Filters incorporated in syringes

Abstract

A safety filter for a syringe according to the present invention comprises a hub which is sealably mounted on a main body of a needle, a tube which is connected to the hub and into which a needle of the needle is inserted, And a filter member mounted on the tube to filter foreign substances, thereby preventing a chemical solution from remaining in the vial container, a displacement of the syringe piston being long, and a failure to fill the syringe with the chemical solution.

Description

Technical Field [0001] The present invention relates to a safety filter, a manufacturing method thereof, and a syringe having the safety filter,

The present invention relates to a syringe, and more particularly, to a safety filter capable of preventing foreign substances such as glass fragments and rubber fragments from being injected into a patient, and a manufacturing method thereof and a syringe having the same.

Generally, a syringe includes a cylinder in which an injection solution is stored, a needle, which is mounted in front of the cylinder, and a plunger, which is inserted linearly in the cylinder and sucks the injection fluid into the cylinder or discharges the injection fluid stored in the cylinder to the outside .

In such a syringe, the upper part of the ampule glass bottle containing the injection solution is cut to open the ampule glass bottle, and the injection needle is inserted through the opened space to suck the injection solution into the cylinder.

In the case of a vial container in which a syringe is sealed and sealed with a rubber seal, a syringe is injected into the cylinder by inserting an injection needle with a rubber seal.

However, when the ampule glass bottle is cut, the glass sludge is introduced into the ampule glass bottle and mixed with the injection solution. Then, when the injection needle is inserted into the vial container through the rubber stopper, the rubber debris penetrates into the injection needle or the inside of the vial container.

When glass fragments or rubber fragments are mixed with the injection solution and injected into the patient's body, various diseases such as phlebitis and sepsis are caused. A syringe filter cap has been developed to solve the problem of such a syringe.

A conventional syringe filter cap is a syringe filter cap that is coupled to a needle assembly to filter foreign materials such as rubber pieces, glass pieces, etc. from an injection solution as disclosed in Japanese Patent Application No. 10-1460465 (Nov. 04, 2014) A hub which is formed in the housing and into which a hub of a needle assembly is inserted and fixed; a ramp extending from the hub insertion path and capable of being inserted without being hung on the needle of the injection needle assembly; A needle extending from the ramp to insert a needle of the needle assembly; a filter attached to the one end of the needle in front of the injection needle by melt adhesion; A ventilation groove formed in the outer surface of the housing of the injection needle insertion portion and serving as a passage through which air flows, A detachable support formed on an outer surface of the housing of the hub insertion portion, a housing coupling portion in which a front portion of the housing is inserted and fixedly coupled, and a tubular metal having a tip portion penetrating the rubber stopper of the vial in an open- Tip.

Such a syringe filter cap is equipped with a metal tip at the end of the housing to penetrate the rubber cap of the vial container.

However, in the conventional syringe filter cap as described above, the diameter of the metal tip must be made large so as to secure the cross-sectional area of the filter, and an inclined portion is formed at the end of the metal tip so as to penetrate the rubber stopper. 6, when the metal tip 120 is in contact with the bottom surface of the vial container 110, the diameter of the metal tip 120 is large, so that the inclined portion of the metal tip 120 is contacted with the chemical liquid There is a problem that a chemical solution stored in the vial container can not be completely injected into the vial container 110 because the space 130 is formed.

In addition, since the diameter of the metal tip is large in the conventional syringe filter cap, the internal space is large, and accordingly, when the drug solution is injected into the syringe, the response becomes poor and the displacement of the syringe piston becomes long, .

In addition, since the conventional syringe filter cap has a limitation in widening the cross-sectional area of the filter member, there is a problem that it is difficult to inject the drug solution into the syringe due to the flow resistance generated when the drug solution passes through the filter member.

Patent Document 1: Registered Patent Publication No. 10-1460465 (Nov. 04, 2014)

SUMMARY OF THE INVENTION It is therefore an object of the present invention to provide a safety filter capable of reducing the diameter of a metal barrel and preventing the chemical liquid from remaining in the vial container, the displacement of the plunger being long, One syringe.

It is another object of the present invention to provide a safety filter which is easy to inject a chemical liquid into a syringe by allowing the chemical liquid to smoothly pass through the filter member by increasing the sectional area of the filter member, a method for manufacturing the same, and a syringe having the same.

In order to achieve the above object, a safety filter for a syringe according to the present invention comprises a hub which is sealably mounted to a main body of a needle, a tube connected to the hub and into which a needle portion of the needle is inserted, A metal tube to which the tube is inserted, and a filter member mounted on the tube to filter foreign matter.

The hub has a first connection part to which the tube is connected, a second connection part having a larger inner diameter than the first connection part in front of the first connection part and connected to the metal barrel, As shown in Fig.

A first sealing portion extending from the first connection portion and formed in an inclined shape so as to be in close contact with a first outer surface of the needle, a second sealing portion extending from the first sealing portion and being in close contact with a second outer surface of the needle, And a third sealing portion formed to have an inner diameter larger than that of the second sealing portion and closely attached to the third outer surface of the injection needle.

The tube may be formed with a filter mounting portion to which a filter member is mounted at an end thereof, and the filter mounting portion may be formed as an inclined surface having an inclination angle [theta] so as to increase the cross-sectional area of the filter member.

The inclination angle [theta] of the filter mounting portion may be 10 [deg.] To 45 [deg.].
The filter member may be composed of a nanofiber membrane of a three-dimensional network structure having micropores provided by electrospinning of a polymeric material.
The filter member may also comprise a porous support and a nanofiber membrane of a three dimensional network structure having micropores deposited on the porous support and provided by electrospinning of the polymeric material.

delete

The porous support may include a core portion disposed at the center, and a shell portion disposed to be wrapped around the outer surface of the core portion and melted at a lower temperature than the core portion.

The core portion may be formed of a resin material that melts at a temperature of 180 ° C or higher, and the shell portion may be formed of a resin material melting at 110 ° C to 140 ° C.

The membrane may be formed by preparing a nanofiber by electrospinning a spinning solution obtained by mixing an electrospun polymer material and a solvent at a predetermined ratio, and storing the nanofiber in a porous support.

A method for manufacturing a safety filter for a syringe according to the present invention includes the steps of forming a filter mounting portion having an inclination angle (?) At an end portion of a tube, fusing a filter member to the filter mounting portion, And connecting the tube and the metal barrel to the hub.

Wherein the step of fusing the filter member comprises the steps of cutting the filter member into the same shape as the filter mounting portion, connecting the two cut filter members by a plurality of bridges, and fusing the filter member to the filter mounting portion, And cutting to remove the remaining portion of the filter member.

Wherein the filter member comprises a porous support and a membrane formed in the form of a nanofiber web laminated to the porous support and electrospinning the polymeric material to have micropores, And the shell portion of the porous support may be melted and fused to the filter mounting portion.

1 is an exploded perspective view of a syringe according to an embodiment of the present invention.
2 is a cross-sectional view of a safety filter according to an embodiment of the present invention.
3 is a partial enlarged view of a safety filter according to an embodiment of the present invention.
4 is a side view of a filter mounting portion of a tube according to an embodiment of the present invention.
5 is a front view of a filter mounting portion of a tube according to an embodiment of the present invention.
Figure 6 is a cross-sectional view of a conventional filter cap inserted into a vial container.
7 is a cross-sectional view of a safety filter according to an embodiment of the present invention inserted into a vial container.
8 is a cross-sectional view of a filter member according to an embodiment of the present invention.
9 is a cross-sectional view of a porous support according to an embodiment of the present invention.
FIG. 10 is a flow chart showing a manufacturing process of a safety filter according to an embodiment of the present invention.
11 is a plan view of a filter member according to an embodiment of the present invention.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings. The sizes and shapes of the components shown in the drawings may be exaggerated for clarity and convenience. In addition, terms defined in consideration of the configuration and operation of the present invention may be changed according to the intention or custom of the user, the operator. Definitions of these terms should be based on the content of this specification.

Referring to FIGS. 1 and 2, a syringe according to an embodiment of the present invention includes a cylinder 10 in which an injection liquid is stored, a cylinder 10 installed to be linearly movable in the cylinder 10, The injection needle 20 mounted on the front of the cylinder 10 and the injection liquid which is detachably mounted on the injection needle 20 and stored in an ampule glass bottle or a vial container is injected into the cylinder 10 And a safety filter 40 for filtering foreign substances such as glass fragments and rubber fragments and storing only the pure injected liquid in the cylinder 10.

The injection needle 20 is composed of a body portion 22 which is sealably mounted on the cylinder 10 and a needle portion 24 integrally connected to the body portion 22 and made of a metal material.

The safety filter 40 includes a hub 42 that is sealably mounted to the body 22 of the needle 20 and a needle 42 that is connected to the hub 42 and into which the needle portion 24 of the needle 20 is inserted A metal tube 46 connected to the hub 42 and inserted into the tube 44 and penetrating the rubber stopper of the vial vessel and a filter member 50 mounted on the tube 44 for filtering the foreign matter ).

The hub 42 has a first connection portion 62 to which the tube 44 is connected and a second connection portion 62 which is formed in front of the first connection portion 62 to have a larger inner diameter than the first connection portion 62, A second connection portion 64 and sealing portions 66, 68, 70 which are tightly sealed to the outer surface of the main body portion 22 of the injection needle.

The sealing portions 66, 68 and 70 include a first sealing portion 66 extending from the first connection portion 62 and formed in an inclined shape so as to be in close contact with the inclined first outer surface 32 of the injection needle 20 A second sealing portion 68 which extends from the first sealing portion 66 and is brought into close contact with the second outer surface 34 of the needle 20 and a second sealing portion 68 which is larger in inner diameter than the second sealing portion 68, And a third sealing portion 70 that is in close contact with the third outer surface 36 of the second sealing member 20.

The hub 44 is made of a resin material and the tube 44 and the metal barrel 46 can be connected by a method such as heat welding or bonding and the tube 44 and the metal barrel 46 And can be molded integrally with the hub 42. [

The hub 42 and the injection needle 20 can be kept sealed by the first seal portion 66, the second seal portion 68 and the third seal portion 70 so that the chemical agent is injected into the syringe It is possible to prevent the wind from leaking and to smoothly inject the chemical into the syringe.

The tube 44 is formed of a resin material and has a larger inner diameter than the outer diameter of the needle portion 24 so that the needle portion 24 of the injection needle 20 can be inserted. A filter mounting portion 80 is formed.

Here, the filter mounting portion 80 is formed as an inclined surface so that the sectional area of the filter member 50 can be increased.

3 to 5, the filter mounting portion 80 is formed as an inclined surface at a predetermined angle to the end portion of the tube 44 so that the cross section of the filter mounting portion 80 is elliptical, The cross-sectional area of the filter member 50 can be increased.

The inclination angle &thetas; of the filter mounting portion 80 may be 10 DEG to 45 DEG. Preferably, when the inclination angle [theta] of the filter mounting portion 80 is 10 [deg.] To 20 [deg.], The cross-sectional area of the filter member 50 can be maximized.

Sectional area of the filter member according to the inclination angle of the filter mounting portion 80 is as shown in Table 1 below.

The inclination angle? 10 ° 15 ° 20 ° 25 ° 30 ° 35 ° 40 ° 45 ° Cross-sectional area (A) 5.49 3.86 2.78 2.25 1.9 1.66 1.48 1.35 Length (A) 8.64 5.80 4.39 3.55 3.00 2.62 2.33 2.12 Sectional area (B) 4.72 3.16 2.39 1.93 1.63 1.42 1.27 1.16 Length (B) 6.33 4.25 3.22 2.60 2.22 1.92 1.71 1.56 The filter member
Sectional area 2.45 2.00 1.74 1.56 1.44 1.34 1.27 1.22

The outer diameter of the tube is 1.5, the inner diameter is 1.1, the inclination angle is the inclination angle of the filter mounting portion formed at the tube end shown in Fig. 4, and the cross-sectional area A is the outer surface sectional area of the filter mounting portion shown in Fig. , The length A is the outer surface length of the filter mounting part, the cross-sectional area B is the inner surface sectional area of the filter mounting part, and the length B is the inner surface length of the filter mounting part.

Thus, as shown in Table 1, the smaller the inclination angle? Of the filter mounting portion 80, the larger the cross-sectional area of the filter member 50 can be. For example, when the inclination angle [theta] of the filter mounting portion 80 is 10 [deg.], The sectional area of the filter member 50 can be increased to 2.45.

The present invention can maximize the cross-sectional area of the filter member 50 while reducing the inner diameter of the tube 44 by giving the inclination angle? To the filter mounting portion 80.

The filter member 50 can be attached to the filter mounting portion 80 by various methods such as heat fusion, ultrasonic fusion bonding, and bonding.

The metal barrel 46 is made of SUS material and formed to have a larger inner diameter than the outer diameter of the tube 44 so that the tube 44 can be inserted therein and is formed into a pointed shape do.

7, since the outer diameter of the metal barrel 46 is small, the safety filter 40 of the present invention can completely absorb the chemical solution stored in the vial container 110, as shown in FIG. However, as shown in FIG. 6, the diameter of the conventional metal tip 120 is increased in order to secure a sufficient space for mounting the filter, so that the chemical solution stored in the vial container 110 is not completely sucked I can not.
The filter member 50 consists of a nanofiber membrane of a three-dimensional network structure with micropores provided by electrospinning of a polymeric material.

8, the filter member 50 includes a membrane 52 formed in the form of a nanofiber web having micropores by electrospinning a polymeric material, a porous support 52, which is laminated on one surface or both surfaces of the membrane 52, (54, 56).

In the embodiment of the present invention, the structure in which the filter member 50 is laminated with the porous supports 54 and 56 and the nanofiber web-shaped membrane 52 has been illustrated and described. However, the filter member is not limited to the nanofiber web- Alternatively, a plurality of such membranes may be stacked.
The porous supports 54 and 56 may include a first porous support 54 that is laminated on one side of the membrane 52 and a second porous support 56 that is laminated on the other side of the membrane 52.

Here, the structure in which the porous supports 54 and 56 are laminated only on one side of the membrane 52 is also applicable. The porous supports 54 and 56 and the membrane 52 may be stacked in two or more layers when it is necessary to improve the filtering ability according to the purpose of use.

9, the porous supports 54 and 56 are formed of a PET material and include a core portion 90 disposed at the center and a shell portion 92 wrapped around the outer surface of the core portion 90 .

The core portion 90 is made of a PET material which melts at a temperature of 180 ° C or higher and the shell portion 92 is made of a PET material melted at 110 ° C to 140 ° C.

The filter member 50 is fused to the filter mounting portion 80 by heat or ultrasonic waves. At this time, the porous supporters 54 and 56 of the filter member 50 are melted by heat and fused to the filter mounting portion 80. When the entire porous supporters 54 and 56 are melted by heat, the filter member 50 is deformed There is a possibility that a problem that the edge fused portion of the filter member 80 and the unmelted inner portion of the filter member 80 are separated may occur.

Therefore, in the present invention, the core portion 90 capable of maintaining the shape of the porous supporters 54 and 56 withstanding the melting temperature upon thermal fusion, and the shell portion 92 that is melted during the heat fusion and fused to the filter mounting portion 80 ) To solve the above problem.

The membrane 52 is prepared by preparing a spinning solution comprising a mixture of an electrospun polymer material and a solvent at a predetermined ratio, and spinning the spinning solution to produce nanofibers. The nanofibers are placed on the porous supporters 54, And is formed into a nanofiber membrane of a three-dimensional network structure having fine pores capable of filtering out foreign matter.

The membrane 52 is prepared by preparing a spinning solution comprising a mixture of an electrospun polymer material and a solvent at a predetermined ratio, and spinning the spinning solution to produce nanofibers. When the nanofibers are accumulated in the porous support 54 to a predetermined thickness And is formed into a nanofiber web having fine pores.

The diameter of the nanofibers may be 200 nm to 400 nm.

The porosity of the membrane 52 is 55 to 85% of the total area of the membrane 52 and the average pore of the membrane 52 is 1.5 to 4 μm.

The total thickness of the first porous support 54, the membrane 52 and the second porous support 56 is 50 to 100 탆. The thickness of the membrane 52 may be 3 to 4 탆. .

The thickness of the membrane (52) is freely adjusted according to the time of radiation from the electrospinning device, and the pore size and porosity are determined according to the thickness of the nanofiber web.

Therefore, in this embodiment, the pore size and porosity of the membrane 52 can be freely adjusted, and the pore size can be variously produced according to the kind of filtration.

In the conventional filter, the porosity of the membrane is about 40 to 50% of the total membrane area. In this case, the flow resistance of the injecting liquid passing through the membrane is increased, and there is a problem that the injecting liquid is injected into the cylinder and the use thereof is inconvenient.

Particularly, due to the characteristics of a syringe, a female nurse who is weaker in strength than men usually uses a lot of syringes. When injecting an injection, it is difficult to use a syringe.

In the present invention, the membrane 52 can be formed into a nanofiber web shape by accumulating nanofibers by electrospinning, so that the porosity of the membrane 52 can be 70 to 80% of the total area of the membrane 52, The flow resistance of the injection liquid passing through the membrane 52 can be minimized.

The porous supports 54 and 56 may be formed of a nonwoven fabric or a net made of metal or resin. Any support may be used as long as the porous support 60 has a pore through which the injectable solution can pass and can support the membrane 52.

The polymeric material used in the present invention is capable of electrospinning, for example, a hydrophilic polymer and a hydrophobic polymer, and one or more of these polymers may be used in combination.

The polymer material usable in the present invention is not particularly limited as long as it is soluble in an organic solvent for electrospinning and is capable of forming nanofibers by electrospinning. For example, polyvinylidene fluoride (PVdF), poly (vinylidene fluoride-co-hexafluoropropylene), perfluoropolymers, polyvinyl chloride, polyvinylidene chloride or copolymers thereof, polyethylene glycol di Polyoxyethylene-polyoxypropylene oxide, polyethylene glycol derivatives including alkyl ethers and polyethylene glycol dialkyl esters, polyoxides including poly (oxymethylene-oligo-oxyethylene), polyethylene oxide and polypropylene oxide, polyvinyl acetate, poly (vinylpyrrolidone- Vinyl acetate), polystyrene and polystyrene acrylonitrile copolymers, polyacrylonitrile (PAN), polyacrylonitrile copolymers including polyacrylonitrile methyl methacrylate copolymers, polymethyl methacrylate, polymethyl methacrylate Acrylate copolymer or a mixture thereof.

Examples of usable polymer materials include polyamide, polyimide, polyamideimide, poly (meta-phenylene isophthalamide), polysulfone, polyetherketone, polyetherimide, polyethylene terephthalate, , Aromatic polyesters such as polyethylene naphthalate, polyphosphazenes such as polytetrafluoroethylene, polydiphenoxaphospazene, poly {bis [2- (2-methoxyethoxy) Polyurethane copolymers including polyether urethanes, cellulose acetate, cellulose acetate butyrate, and cellulose acetate propionate.

Of the above polymer materials, PAN, polyvinylidene fluoride (PVdF), polyester sulfone (PES) and polystyrene (PS) may be used alone or polyvinylidene fluoride PVdF) and polyacrylonitrile (PAN), PVDF, PES, PVdF and thermoplastic polyurethane (TPU) may be mixed and used.

The safety filter manufacturing process will be described below.

10 is a process flow diagram illustrating a safety filter manufacturing process according to an embodiment of the present invention.

First, the end of the tube 44 is cut to form a filter mounting portion 80 having a predetermined inclination angle (S10). At this time, when the inclination angle of the filter mounting portion 80 is 10 ° to 20 °, the sectional area of the filter member 50 can be maximized.

Then, the filter member 50 is fused to the filter mounting portion 80 (S20). At this time, as shown in FIG. 11, the filter member 50 is cut in the same shape as the elliptical shape of the filter mounting portion 80, and a plurality of bridges 84 are formed along the circumferential direction.

The filter member 50 is formed of a first filter portion 82 fused to the filter mounting portion 80 and a second filter portion 86 connected to the first filter portion 82 and the plurality of bridges 84 do.

The filter member 50 is disposed on the filter mounting portion 80, and then heat-sealed or ultrasonic-sealed.

The tube 44 is melted at a temperature of 120 ° C to 160 ° C with a PP material and the shell portion 92 of the porous supporters 54 and 56 of the filter member 50 is melted at 110 ° C to 140 ° C, The shell portion 92 and the tube 44 of the tubes 54 and 56 are melted and fused together.

When the bridge 84 of the filter member 50 is cut, the second filter portion 86 is removed.

Then, the tube 44 is inserted into the metal barrel 46, and the metal barrel 46 and the tube 44 are assembled to the hub 42 (S30, S40).

That is, the metallic barrel 46 and the tube 44 are integrally formed by adhering to the first connection portion 62 and the second connection portion 64 of the hub 42 with an adhesive, by heat fusion, or by insert injection.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is clearly understood that the same is by way of illustration and example only and is not to be construed as limited to the embodiments set forth herein. Various changes and modifications may be made by those skilled in the art.

10: cylinder 12: plunger
20: injection needle 22:
24: needle portion 40: safety filter
42: hub 44: tube
46: metal tube 50: filter element
52: membrane 54,56: porous support
80: filter mounting portion 90: core
92: Shell part

Claims (18)

A hub sealably mounted on the body of the needle;
A tube connected to the hub and into which a needle portion of the needle is inserted;
A metallic barrel connected to the hub and into which the tube is inserted; And
And a filter member mounted on the tube for filtering foreign matter,
Wherein the filter member comprises a porous support and a nanofiber membrane laminated to the porous support,
Wherein the porous support includes a core portion disposed at the center and a shell portion wrapped around the outer surface of the core portion and melted at a lower temperature than the core portion. The method according to claim 1,
The hub includes a first connection portion to which the tube is connected,
A second connection part formed in front of the first connection part and having a larger inner diameter than the first connection part and connected to the metal barrel,
And a seal portion that is sealably inserted into an outer surface of the main body of the injection needle. 3. The method of claim 2,
A first sealing portion extending from the first connection portion and formed in an inclined shape so as to be in close contact with a first outer surface of the needle, a second sealing portion extending from the first sealing portion and being in contact with the second outer surface of the needle, And a third sealing portion formed to have an inner diameter larger than that of the second sealing portion and being in close contact with a third outer surface of the injection needle. The method according to claim 1,
Wherein the tube and the metal barrel are connected to the hub by an adhesive bonding method, a heat welding method, or an insert injection method so as to be integrally formed with the hub. The method according to claim 1,
Wherein the tube is formed with a filter mounting portion to which a filter member is mounted at an end thereof, and the filter mounting portion is formed as an inclined surface having an inclination angle &thetas; so as to increase the cross-sectional area of the filter member. 6. The method of claim 5,
And the inclination angle (?) Of the filter mounting part is formed to be 10 ° to 45 °. The method according to claim 1,
Wherein the nanofiber membrane is a three-dimensional network structure having micropores formed by electrospinning of a polymeric material. delete delete delete The method according to claim 1,
Wherein the core part is made of a resin material melted at a temperature of 180 ° C or higher and the shell part is made of a resin material melted at 110 ° C to 140 ° C. The method according to claim 1,
Wherein the diameter of the nanofibers is 200 nm to 400 nm. The method according to claim 1,
Wherein the porosity of the membrane is about 55% to about 85% of the total area of the membrane. A cylinder in which an injection liquid is stored; and a safety filter sealably coupled to the injection needle,
Wherein the safety filter is a safety filter according to any one of claims 1 to 7 and 11 to 13. Forming a filter mounting portion having an inclination angle (?) At an end portion of the tube;
Fusing a filter member to the filter mounting portion;
Assembling the tube into a metal tube; And
Connecting the tube and the metal barrel to a hub,
The step of fusing the filter member
Cutting the filter member into the same shape as the filter mounting portion, connecting the two cut filter members by a plurality of bridges,
And fusing the filter member to the filter mounting portion, and then cutting the bridge to remove the remaining portion of the filter member. delete delete delete
KR1020150088984A 2015-06-23 2015-06-23 Safety filter, manufacturing method and syringe having the same KR101675865B1 (en)

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KR1020150088984A KR101675865B1 (en) 2015-06-23 2015-06-23 Safety filter, manufacturing method and syringe having the same
PCT/KR2016/006530 WO2016208922A1 (en) 2015-06-23 2016-06-20 Safety filter, manufacturing method therefor, and syringe having safety filter

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Cited By (3)

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Publication number Priority date Publication date Assignee Title
KR101710830B1 (en) * 2016-03-28 2017-02-27 유광석 Filter cap for syringe
WO2017065564A1 (en) * 2015-10-14 2017-04-20 주식회사 아모그린텍 Liquid drug-filtering filter medium, method for producing same, and liquid drug-filtering filter module comprising same
US11161752B2 (en) 2015-08-13 2021-11-02 Amogreentech Co., Ltd Portable water-purifying pouch

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