KR101656744B1 - 트리클로산 노출에 대응하는 바다송사리 유전자 및 이를 이용한 수생태계 환경오염 진단 방법 - Google Patents

트리클로산 노출에 대응하는 바다송사리 유전자 및 이를 이용한 수생태계 환경오염 진단 방법 Download PDF

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KR101656744B1
KR101656744B1 KR1020160024104A KR20160024104A KR101656744B1 KR 101656744 B1 KR101656744 B1 KR 101656744B1 KR 1020160024104 A KR1020160024104 A KR 1020160024104A KR 20160024104 A KR20160024104 A KR 20160024104A KR 101656744 B1 KR101656744 B1 KR 101656744B1
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oryzias javanicus
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염승식
조예진
이다영
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Abstract

본 발명은 트리클로산(Triclosan, TCS) 노출에 대응하는 바다송사리(Oryzias javanicus) 유전자 및 이를 이용하여 수생태계 환경오염을 진단하는 방법에 관한 것으로, 구체적으로 바다송사리를 배양하여 트리클로산을 6 ㎍/L농도로 12, 24, 48, 및 72시간 동안 노출시킨 후, 이로부터 RNA를 분리하고, cDNA를 합성한 뒤, Cy3 및 Cy5로 표지하여 혼성화하였고, oligo-마이크로어래이를 제작하여 이를 분석한 결과, 12시간 노출군에서는 93종의 유전자(증가 29종, 감소 64종, 표 1 참조); 24시간 노출군에서는 60종의 유전자(증가 19종, 감소 41종, 표 2 참조); 48시간 노출군에서는 61종(증가 21종, 감소 40종, 표 3 참조); 72시간 노출군에서는 67종(증가 22종, 감소 45종, 표 4 참조)의 유전자 발현이 변화되는 것을 확인하였고, 중복되는 유전자들을 제외한 총 183종(증가 58종, 감소 125종, 표 5 및 표 6 참조)의 유전자들을 선별함으로써, 상기 유전자들은 트리클로산 노출을 확인할 수 있는 바이오마커로 유용하게 사용될 수 있다.

Description

트리클로산 노출에 대응하는 바다송사리 유전자 및 이를 이용한 수생태계 환경오염 진단 방법{Triclosan responsive genes in Oryzias javanicus and the method for diagnosing aquatic environment pollution using the same}
본 발명은 트리클로산(Triclosan, TCS) 노출에 대응하는 바다송사리(Oryzias javanicus) 유전자 및 이를 이용하여 수생태계 환경오염을 진단하는 방법에 관한 것이다.
트리클로산(Triclosan, TCS)은 항균 및 항진균 활성을 갖는 화학물질로, 치약, 방취제, 비누, 세제 등과 같은 개인 청결용품에 사용된다. 미국 식품의약국(US Food and Drug Administratin)에 의하면 트리클로산이 인간에게 위험하다고 알려진 것은 아직 없다고 하지만, 그 위해성에 대해서는 계속 논란이 진행 중이다. 즉, 트리클로산 노출에 의해 근육 기능이 저해될 가능성이 있으며, 체내의 호르몬 조절, 특히 에스크로겐 관련 반응과 갑상선 호르몬 관련 반응에 문제를 일으킬 수도 있는 것으로 알려져 있다.
생물들은 환경오염, 기후변화 및 병원성 미생물의 감염 등과 같은 외부 환경변화에 대응하여, 항상성을 유지하기 위해 생체방어기작을 진화시켜왔다. 이 생체방어기작의 대부분은 특정 유전자의 발현량을 능동적으로 변화시켜, 특정 단백질의 양을 조절하는 것으로 나타난다. 따라서 특정 변화에 대한 특이적인 유전자들을 발굴하여 이들의 발현량 변화를 모니터링한다면, 특정지역의 환경변화에 관한 정보뿐만 아니라, 이러한 환경변화가 생명현상에 미치는 영향 및 생태계의 건강에 관한 정보를 얻을 수 있다.
이에, 본 발명자들은 바다송사리를 대상으로 환경오염에 대응하는 생체지표의 발굴을 시도하고 있으며, 트리클로산 노출에 대한 특이 유전자 후보의 확보 및 검출을 위해, 송사리와 같은 속에 속하는 바다송사리(Oryzias javanicus) 유전자 해즈켐 피쉬 배열(HazChem Fish Array)를 활용한, 마이크로어래이 실험분석을 통해, 트리클로산 12시간 노출군에서는 93종의 유전자(증가 29종, 감소 64종); 24시간 노출군에서는 60종의 유전자(증가 19종, 감소 41종); 48시간 노출군에서는 61종(증가 21종, 감소 40종); 72시간 노출군에서는 67종(증가 22종, 감소 45종)의 유전자 발현이 변화되는 것을 확인하였고, 중복되는 유전자들을 제외한 총 183종(증가 58종, 감소 125종)의 유전자들이 트리클로산 노출에 의해 발현량이 변화됨을 확인함으로써, 이들 유전자들은 트리클로산 노출을 확인할 수 있는 바이오마커로 활용하여, 트리클로산 노출 여부를 확인할 수 있는 어류 생체지표 및 이들 유전자 생체지표들의 발현량 변화를 규명함으로써 본 발명을 완성하였다.
본 발명의 목적은 트리클로산(Triclosan, TCS) 노출에 대응하여 발현량이 변화된 바다송사리(Oryzias javanicus) 유전자 및 이를 이용한 트리클로산 노출 여부를 확인하는 방법을 제공하는 것이다.
상기 목적을 달성하기 위하여, 본 발명은 서열번호 1 내지 183으로 기재되는 모든 유전자 각각의 핵산 서열의 올리고뉴클레오티드 전부 또는 그의 상보가닥 분자가 집적된, 시료내 트리클로산(Triclosan, TCS) 노출 여부 검출용 마이크로어래이 칩(microarray chip)을 제공한다.
또한, 본 발명은
1) 피검 시료에 노출된 실험군의 바다송사리와, 정상 대조군의 바다송사리에서 각각 RNA를 분리하는 단계;
2) 단계 1)의 실험군 및 대조군의 RNA로부터 cDNA를 합성하면서 실험군과 대조군을 각기 다른 형광물질로 표지하는 단계;
3) 단계 2)의 각기 다른 형광물질로 표지된 cDNA를 제 1항의 마이크로어래이 칩과 혼성화시키는 단계;
4) 반응한 마이크로어래이 칩을 분석하는 단계; 및
5) 분석한 데이터에서 제 1항의 마이크로어래이 칩에 집적된 유전자 발현 정도를 대조군과 비교하여 확인하는 단계를 포함하는, 시료내 트리클로산(Triclosan, TCS) 노출 여부 검출 방법을 제공한다.
또한, 본 발명은
1) 피검시료에 노출된 실험군의 바다송사리(Oryzias javanicus)와, 정상 대조군의 바다송사리에서 각각 RNA를 분리하는 단계;
2) 단계 1)의 RNA를, 서열번호 1 내지 183으로 기재되는 각각의 유전자에 상보적이고 유전자를 증폭할 수 있는 프라이머 쌍을 모두 사용하여 정량 실시간 RT-PCR(Quantitative real-time reverse transcript polymerase chain reaction, qRT-PCR)을 수행하는 단계; 및
3) 단계 2)의 유전자 산물을 대조군과 비교하여 발현 정도를 확인하는 단계를 포함하는, 시료내 트리클로산(Triclosan, TCS) 노출 여부 검출 방법을 제공한다.
또한, 본 발명은 상기 마이크로어래이 칩을 포함하는 트리클로산(Triclosan, TCS) 노출 여부 검출용 키트를 제공한다.
아울러, 본 발명은 서열번호 1 내지 183으로 기재되는 각각의 유전자에 상보적이고 유전자를 증폭할 수 있는 프라이머 쌍을 모두 포함하는 트리클로산(Triclosan, TCS) 노출 여부 검출용 키트를 제공한다.
본 발명에서 송사리와 같은 속에 속하는 바다송사리(Oryzias javanicus) 유전자 해즈켐 피쉬 배열(HazChem Fish Array)를 활용한, 이종간의 마이크로어래이 실험분석을 통해, 트리클로산 12시간 노출군에서는 93종의 유전자(증가 29종, 감소 64종); 24시간 노출군에서는 60종의 유전자(증가 19종, 감소 41종); 48시간 노출군에서는 61종(증가 21종, 감소 40종); 72시간 노출군에서는 67종(증가 22종, 감소 45종)의 유전자 발현이 변화되는 것을 확인하였고, 중복되는 유전자들을 제외한 총 183종(증가 58종, 감소 125종)의 유전자들이 트리클로산 노출에 의해 발현량이 변화됨을 확인함으로써, 이들 유전자들은 트리클로산 노출을 확인할 수 있는 바이오마커로 유용하게 사용될 수 있다.
도 1은 트리클로산(Triclosan, TCS)에 노출한 바다송사리(Oryzias javanicus)의 차등 발현 유전자 프로파일링 Hierachial clustering 결과를 나타낸 도이다. 바다송사리의 트리클로산에 대한 반수치사농도(Lethal concentration 50, LC50, 96시간에서 0.60 mg/L)의 약 1/100에 해당되는 6 μg/L(ppb)에 12시간, 24시간, 48시간, 및 72시간 동안 노출시켰다.
이하, 본 발명을 상세히 설명한다.
본 발명은 트리클로산(triclosan; TCS) 노출에 대응하여 발현이 변화하는 바다송사리(Oryzias javanicus) 유래의 유전자를 발굴하여, 상기 트리클로산 노출에 대하여 발현량이 변화하는 바다송사리 유래 유전자를 집적한 마이크로어래이 칩을 트리클로산 노출 여부 검출 및 수생태계 오염 상태를 진단하는데 이용할 수 있다.
본 발명은 서열번호 1 내지 183으로 기재되는 모든 유전자 각각의 핵산 서열의 올리고뉴클레오티드 전부 또는 그의 상보가닥 분자가 집적된, 시료내 트리클로산 노출 여부 검출용 마이크로어래이 칩(microarray chip)을 제공한다.
상기 유전자는 바다송사리(Oryzias javanicus)로부터 유래된 것이 바람직하고, 서열번호 1 내지 125로 기재되는 유전자로 구성된 군으로부터 선택되는 유전자는 트리클로산 노출에 대응하여 발현이 감소하는 것이 바람직하며, 서열번호 126 내지 183으로 기재되는 유전자로 구성된 군으로부터 선택되는 유전자는 트리클로산 노출에 대응하여 발현이 증가하는 것이 바람직하다.
상기 트리클로산 노출 여부 검출용 마이크로어래이 칩은 당업자에게 알려진 방법으로 제작할 수 있다. 상기 마이크로어래이 칩을 제작하는 방법은 하기와 같다. 상기 탐색된 유전자를 프로브로 이용하여 마이크로어래이 칩의 기판상에 고정화시키기 위해 파이조일렉트릭(piezoelectric) 방식을 이용한 마이크로피펫팅(micropipetting)법 또는 핀(pin) 형태의 스폿터(spotter)를 이용한 방법 등을 사용하는 것이 바람직하나 이에 한정되지 않는다. 상기 마이크로어래이 칩의 기판은 아미노-실란(amino-silane), 폴리-L-라이신(poly-Llysine) 및 알데히드(aldehyde)로 이루어진 군에서 선택되는 하나의 활성기가 코팅된 것이 바람직하나 이에 한정되지 않는다. 또한, 상기 기판은 슬라이드 글라스, 플라스틱, 금속, 실리콘, 나일론 막, 및 니트로셀룰로스 막으로 이루어진 군에서 선택될 수 있으나 이에 한정되지 않는다.
또한, 본 발명은
1) 피검 시료에 노출된 실험군의 바다송사리와, 정상 대조군의 바다송사리에서 각각 RNA를 분리하는 단계;
2) 단계 1)의 실험군 및 대조군의 RNA로부터 cDNA를 합성하면서 실험군과 대조군을 각기 다른 형광물질로 표지하는 단계;
3) 단계 2)의 각기 다른 형광물질로 표지된 cDNA를 제 1항의 마이크로어래이 칩과 혼성화시키는 단계;
4) 반응한 마이크로어래이 칩을 분석하는 단계; 및
5) 분석한 데이터에서 제 1항의 마이크로어래이 칩에 집적된 유전자 발현 정도를 대조군과 비교하여 확인하는 단계를 포함하는, 시료내 트리클로산(triclosan; TCS) 노출 여부 검출 방법을 제공한다.
상기 시료는 생체시료, 식품시료, 화학시료, 공업시료, 임상시료 및 환경시료로 구성된 군으로부터 선택되는 어느 하나인 것이 바람직하고, 상기 단계 2)의 형광물질은 Cy3, Cy5, FITC(poly L-lysine-fluorescein isothiocyanate), RITC(rhodamine-B-isothiocyanate) 및 로다민(rhodamine)으로 이루어진 군으로부터 선택되는 어느 하나인 것이 바람직하다.
또한, 본 발명은
1) 피검시료에 노출된 실험군의 바다송사리(Oryzias javanicus)와, 정상 대조군의 바다송사리에서 각각 RNA를 분리하는 단계;
2) 단계 1)의 RNA를, 서열번호 1 내지 183으로 기재되는 각각의 유전자에 상보적이고 유전자를 증폭할 수 있는 프라이머 쌍을 모두 사용하여 정량 실시간 RT-PCR(Quantitative real-time reverse transcript polymerase chain reaction, qRT-PCR)을 수행하는 단계; 및
3) 단계 2)의 유전자 산물을 대조군과 비교하여 발현 정도를 확인하는 단계를 포함하는, 시료내 트리클로산(triclosan; TCS) 노출 여부 검출 방법을 제공한다.
상기 시료는 생체시료, 식품시료, 화학시료, 공업시료, 임상시료 및 환경시료로 구성된 군으로부터 선택되는 어느 하나인 것이 바람직하다.
또한, 본 발명은 상기 마이크로어래이 칩을 포함하는 트리클로산(triclosan; TCS) 노출 여부 검출용 키트를 제공한다.
상기 키트는 스트렙타비딘-알칼리 탈인화효소 접합물질(strepavidin -like phosphatease conjugate), 화학형광물질(chemiflurorensce) 및 화학발광물질(chemiluminescent)로 이루어진 형광물질군으로부터 선택되는 어느 하나를 추가적으로 포함하는 것이 바람직하고, 혼성화에 사용되는 완충용액, RNA로부터 cDNA(complementary DNA)를 합성하기 위한 역전사효소, dNTPs(deoxynucleotide triphosphates) 및 rNTPs(ribonucleotide triPhosphates, 사전 혼합형 또는 분리 공급형), 표식시약, 및 세척 완충용액으로 이루어진 반응 시약군으로부터 선택되는 어느 하나를 추가적으로 포함하는 것이 바람직하다.
아울러, 본 발명은 서열번호 1 내지 183으로 기재되는 각각의 유전자에 상보적이고 유전자를 증폭할 수 있는 프라이머 쌍을 모두 포함하는 트리클로산(triclosan; TCS) 노출 여부 검출용 키트를 제공한다.
본 발명의 구체적인 실시예에서, 본 발명자들은 바다송사리를 배양하여 트리클로산을 6 ㎍/L농도로 12, 24, 48, 및 72시간 동안 노출시킨 후, 이로부터 RNA를 분리하고, cDNA를 합성한 뒤, Cy3 및 Cy5로 표지하여 혼성화하였고, oligo-마이크로어래이를 제작하여 이를 분석한 결과, 12시간 노출군에서는 93종의 유전자(증가 29종, 감소 64종, 표 1 참조); 24시간 노출군에서는 60종의 유전자(증가 19종, 감소 41종, 표 2 참조); 48시간 노출군에서는 61종(증가 21종, 감소 40종, 표 3 참조); 72시간 노출군에서는 67종(증가 22종, 감소 45종, 표 4 참조)의 유전자 발현이 변화되는 것을 확인하였고, 중복되는 유전자들을 제외한 총 183종(증가 58종, 감소 125종, 표 5 및 표 6 참조)의 유전자들을 선별하였다.
따라서, 상기 유전자들을 포함하는 바이오마커를 프로브로 이용하여 피검체와 대조군의 RNA를 추출하여 상기 마커 유전자들의 발현 변화를 비교분석함으로써, 피검체가 트리클로산에 노출되었는지 여부를 확인할 수 있다. 즉, 만약 피검체가 트리클로산에 노출되었다면, 표 6에 기재되어 있는 유전자들의 발현량이 대조군에 비해 피검체에서 증가한 것으로 나타날 것이고, 표 5에 기재되어 있는 유전자들의 발현량은 대조군에 비해 피검체에서 감소한 것으로 나타날 것이므로, 이를 이용하여 피검체의 트리클로산의 노출 여부를 확인할 수 있다.
이하, 본 발명을 실시예에 의해서 상세히 설명한다.
단, 하기 실시예는 본 발명을 예시하기 위한 것일 뿐, 본 발명이 하기 실시예에 의해서 한정되는 것은 아니다.
< 실시예 1> 바다송사리의 배양 및 트리클로산 노출
<1-1> 바다송사리의 배양
바다송사리(Oryzias javanicus)는 세 종류의 필터(100, 10 및 1 ㎛, Spun Polypropylene filter cartilage, Heathy)를 거친 자연 해수에 배양하였다. 수중 히터를 이용하여 수온은 섭씨 25도로 고정하였으며, 하루에 한번 아르테미아(Artemia) 유생을 먹이로 공급하였다.
<1-2> 트리클로산 노출 조건 확립
배양수조에서 사육중인 바다송사리 수컷을 여과된 해수 2 L가 담긴 3 L 비커로 10마리씩 옮기고, 24시간 동안 순치시켰다. 그 이후 바다송사리 수컷을 5개체씩 트리클로산 6 ㎍/L에 12, 24, 48, 72시간 동안 노출하였다. 노출 농도는 바다송사리의 트리클로산 반수치사농도(Lethal concentration 50, LC50, 96시간에서 0.60 mg/L)의 약 1/100에 해당되는 매우 낮은 수준의 농도로 결정하였다. 노출 이후, 바다송사리를 한 마리씩 얼음물로 옮겨, 순간적으로 기절시킨 후, 머리를 잘라내고, 배를 갈라, 간을 적출하였다.
< 실시예 2> 트리클로산 노출에 의한 유전자 발현량 변화 측정
<2-1> RNA 추출 및 cDNA 합성
노출 시험군(12, 24, 48, 72 시간) 및 노출하지 않은 대조군의 바다송사리 간에 TRI Reagent 용액(Molecular Research Center Inc, Cincinnati, Ohaio, USA) 1 ㎖를 넣고, 유리 균질기(glass homogenizer)를 이용하여 균질화하고, 실온에 5분간 방치하였다. 클로로포름 200 ㎕를 첨가하여 잘 섞은 후, 실온에서 10분간 방치하고, 15분간 원심분리(12,000×g, 4℃)하였다. 그런 다음, 상층액을 수득하여, 아이소프로판올(isopropanol) 500 ㎕를 넣고, 상온에 5분간 방치하였다. 약 20 분간 원심분리(12,000×g, 4℃)한 후, 용액을 제거하여 침전물만을 취합하였고, 상기 침전물에 70% 에탄올 용액 50 ㎕를 넣어 5분간 원심분리한 뒤, 에탄올 용액을 제거하고 침전된 RNA를 건조시켰다. 건조 후, 적당량의 에틸피로카보네이트(diethylpyrocarbonate, DEPC)로 처리한 멸균수에 용해하였다.
<2-2> Cy3 및 Cy5 표지
정제된 노출군 및 대조군의 전체 RNA는 Agilent's Low RNA Input Linear Amplification Kit Plus (Agilent Technologies, USA)를 사용하여 제조사의 프로토콜을 따라 다음과 같이 Cy3 및 Cy5로 표지하였다.
구체적으로, RNA 1 ㎍을 dT-프로모터 프라이머(dT-promoter primer)와 MMLV-역전사효소(MMLV-Reverse transcriptase)와 혼합하여 40℃에서 2시간 동안 역전사반응을 수행하였다. 그런 다음, T7 중합효소(T7 polymerase)를 첨가하여 40℃에서 2시간 동안 선형 증폭(linear amplification)을 수행하였다. 이와 같은 증폭과정을 통해 실험군 및 대조군의 시료를 각각 Cy3-CTP와 Cy5-CTP로 표지하였다.
<2-3> 혼성화 (Hybridization) 및 스캐닝(scanning)
형광물질이 라벨링된 cRNA 시료를 Qiagen PCR purification kit을 사용하여 정제하고, 증류수로 용출하였다. 정제된 형광표지-cRNA 시료를 혼성화 완충액(hybridization buffer)(3×SSC, 0.3% SDS, 50% 포름아미드(formamide), 20 ㎍ Cot-1 DNA, 20 ㎍ 효모균(yeast) tRNA)에 첨가한 후, microcon YM-30으로 농축하여 혼성화 혼합물을 만들었다. 혼성화 혼합물을 95℃로 3분 동안 가열하여 변성시키고 12,000×g에서 30초간 원심분리하며 온도를 낮추었다. 제조된 바다송사리 oligo-마이크로어래이(microarray, HazChem Fish Array)에 커버슬립(coverslip)을 덮고, 변성시킨 혼성화 혼합물을 파이펫팅(pipetting)하였다. 그 후, 상기 마이크로어래이를 GT-Hyb 챔버(Chamber)에 넣고 65℃에서 16시간 동안 반응시켜 혼성화를 시켰고, 혼성화가 끝난 후, 챔버에서 마이크로어래이를 꺼내어 세척과정을 수행하고, 마이크로어래이를 회전하여 건조한 후 스캐닝 할 때까지 암실에서 보관하였다. 실험이 완료된 HazChem Fish Array를 Axon GenePix 4000B scanner(Axon Instrument, USA)를 사용하여 스캔하였으며, GenePix Pro 6.0 program을 이용하여, 스캔 이미지로부터 각 점을 그리딩 파일(gridding file)을 이용하여 그리딩하고, 정량화하여 각 점의 Cy5/Cy3 강도 및 비율등의 분석값이 포함된 GPR 파일(GPR file)을 얻었다.
< 실시예 3> 마이크로어래이 자료 분석
GenePix Pro Program에서 얻어진 GPR 파일로부터, 분석 프로그램인 GeneSpring 7.3.1(Agilent Technologies, USA)를 이용하여 아래와 같이 분석을 수행하였다:
표준화(Normalization)는 LOWESS(locally weighted regression scatterplot smoothing)를 이용하여 수행하였고, 신뢰할 수 있는 유전자(Reliable gene)는 중앙값의 합이 배경(background) 보다 낮거나, 각 화소(pixel) 값의 표준편차가 유의하지 않은 점을 플래그 아웃(flag-out)함으로써 유의한 유전자를 얻었다. 유의한 유전자(Significant genes)는 평준화된 비율(normalized ratio) 값이 10배 이상 차이를 보이는 점을 선별하였다.
<3-1> 특이유전자후보군의 확인
1차적으로 트리클로산 노출 시간별 유전자 발현량이 2배이상 변화되는 유전자들을 선별하였다. 노출 실험은 3회 실시하였으며, 통계적으로 유의한 유전자들을 선별하였다.
그 결과, 12시간 노출군에서는 93종의 유전자(증가 29종, 감소 64종; 표 1); 24시간 노출군에서는 60종의 유전자(증가 19종, 감소 41종; 표 2); 48시간 노출군에서는 61종(증가 21종, 감소 40종; 표 3); 72시간 노출군에서는 67종(증가 22종, 감소 45종; 표 4)의 유전자 발현이 변화되는 것으로 분석되었다. 이들 중 중복되는 유전자들을 제외하면, 표 5 및 표 6에 나타난 바와 같이, 총 183종의 유전자들이 트리클로산 노출에 의해 발현량이 변화되는 것으로 파악되며(표 5 및 표 6), 이들 유전자들은 트리클로산 노출을 확인할 수 있는 바이오마커로 활용 가능할 것으로 생각된다.
바다송사리 TCS 12시간 노출군에서 발현량이 2배 이상 변화되는 유전자 목록(93종)
유전자 실험 1 실험 2 실험 3
annexin max3 [Oryzias javanicus] 0.487 0.521 0.455
c-fos protein [Oryzias javanicus] 0.034 0.021 0.058
cytochrome P450 2P3 [Oryzias javanicus] 0.486 0.475 0.498
cytoglobin-1 [Oryzias javanicus] 4.384 3.350 5.738
histone-lysine N-methyltransferase EZH1-like [Oryzias javanicus] 0.464 0.533 0.405
ketohexokinase [Oryzias javanicus] 0.287 0.317 0.259
ADP-ribosylation factor-like protein 5C-like [Oryzias javanicus] 0.082 0.060 0.113
AN1-type zinc finger protein 5-like isoform 1 [Oryzias javanicus] 0.086 0.079 0.093
anti-apoptotic protein NR13-like [Oryzias javanicus] 0.382 0.339 0.431
apolipoprotein A-IV-like [Oryzias javanicus] 0.468 0.532 0.412
apolipoprotein C-II-like isoform X1 [Oryzias javanicus] 8.319 7.374 9.386
arrestin domain-containing protein 3-like isoform 1 [Oryzias javanicus] 2.073 2.271 1.893
baculoviral IAP repeat-containing protein 2-like isoform X5 [Oryzias javanicus] 0.472 0.449 0.497
charged multivesicular body protein 6-like [Oryzias javanicus] 2.010 1.955 2.066
cholesterol 7-alpha-monooxygenase-like [Oryzias javanicus] 0.334 0.325 0.344
coiled-coil domain-containing protein 43-like isoform 1 [Oryzias javanicus] 0.469 0.414 0.531
cytochrome P450 2D10-like isoform 1 [Oryzias javanicus] 0.398 0.383 0.414
cytochrome P450 2J6-like isoform 1 [Oryzias javanicus] 0.484 0.441 0.530
death domain-associated protein 6-like [Oryzias javanicus] 0.443 0.452 0.434
dimethylglycine dehydrogenase, mitochondrial-like [Oryzias javanicus] 0.500 0.571 0.438
dipeptidase 1-like [Oryzias javanicus] 0.210 0.248 0.179
disintegrin and metalloproteinase domain-containing protein 12-like [Oryzias javanicus] 2.099 2.154 2.045
DNA-binding protein inhibitor ID-1-like [Oryzias javanicus] 2.254 2.290 2.218
dnaJ homolog subfamily C member 15-like isoform X1 [Oryzias javanicus] 0.281 0.324 0.245
E3 ubiquitin-protein ligase TRIM33-like, partial [Oryzias javanicus] 0.435 0.469 0.403
E3 ubiquitin-protein ligase ZNRF2-like [Oryzias javanicus] 2.223 2.361 2.093
erythrocyte band 7 integral membrane protein-like [Oryzias javanicus] 0.316 0.308 0.324
eukaryotic translation initiation factor 4 gamma 2-like, partial [Oryzias javanicus] 0.298 0.262 0.338
FAST kinase domain-containing protein 3-like [Oryzias javanicus] 0.461 0.495 0.429
fibulin-2-like [Oryzias javanicus] 11.190 10.353 12.094
filamin A-interacting protein 1-like [Oryzias javanicus] 2.768 2.985 2.568
fructose-bisphosphate aldolase A [Oryzias javanicus] 0.278 0.235 0.328
fructose-bisphosphate aldolase A [Oryzias javanicus] 0.306 0.277 0.338
fructose-bisphosphate aldolase B [Oryzias javanicus] 2.551 2.877 2.263
gap junction Cx32.2 protein-like [Oryzias javanicus] 0.390 0.470 0.324
heme oxygenase-like [Oryzias javanicus] 3.621 3.032 4.324
hepcidin-like [Oryzias javanicus] 0.293 0.352 0.244
heterogeneous nuclear ribonucleoprotein A/B-like [Oryzias javanicus] 0.242 0.234 0.249
heterogeneous nuclear ribonucleoprotein Q-like [Oryzias javanicus] 0.496 0.479 0.513
high mobility group protein HMG-I/HMG-Y-like isoform X1 [Oryzias javanicus] 0.385 0.398 0.373
interleukin-1 receptor-like 2-like [Oryzias javanicus] 2.165 2.617 1.791
ketohexokinase-like [Oryzias javanicus] 0.320 0.359 0.285
ketohexokinase-like isoform X3 [Oryzias javanicus] 0.299 0.307 0.292
ligand of Numb protein X 2-like [Oryzias javanicus] 0.439 0.418 0.461
lysine-specific demethylase 5B-like [Oryzias javanicus] 2.149 1.920 2.406
lysine-specific histone demethylase 1B-like [Oryzias javanicus] 2.103 1.985 2.229
mid1-interacting protein 1-like isoform 1 [Oryzias javanicus] 0.365 0.308 0.431
mitochondrial import receptor subunit TOM40 homolog [Oryzias javanicus] 0.443 0.370 0.529
motile sperm domain-containing protein 1-like isoform X1 [Oryzias javanicus] 2.120 1.840 2.443
nocturnin-like [Oryzias javanicus] 0.194 0.153 0.244
nuclear distribution protein nudE-like 1-B-like [Oryzias javanicus] 0.224 0.231 0.218
nuclear receptor subfamily 1 group D member 1-like [Oryzias javanicus] 2.198 2.449 1.972
nuclear receptor subfamily 2 group F member 1-A-like isoform X1 [Oryzias javanicus] 3.687 3.288 4.135
nucleolar protein 58-like [Oryzias javanicus] 0.337 0.303 0.375
nucleoside diphosphate kinase B-like isoform 1 [Oryzias javanicus] 0.388 0.323 0.467
p21-activated protein kinase-interacting protein 1-like [Oryzias javanicus] 0.456 0.528 0.393
palmitoyl-protein thioesterase 1-like [Oryzias javanicus] 0.378 0.404 0.354
phosphatidylinositol 3-kinase regulatory subunit gamma-like [Oryzias javanicus] 2.414 2.615 2.229
phosphoribosyl pyrophosphate synthase-associated protein 1-like isoform X3 [Oryzias javanicus] 2.591 2.656 2.527
pleckstrin homology domain-containing family A member 6-like [Oryzias javanicus] 0.386 0.389 0.383
polypyrimidine tract-binding protein 1-like [Oryzias javanicus] 2.147 2.467 1.868
pre-rRNA-processing protein TSR1 homolog [Oryzias javanicus] 0.498 0.460 0.540
probable ATP-dependent RNA helicase DDX5-like [Oryzias javanicus] 0.446 0.486 0.409
proline synthase co-transcribed bacterial homolog protein-like [Oryzias javanicus] 0.366 0.375 0.357
protein FAM13A-like [Oryzias javanicus] 0.366 0.455 0.294
protein Tob1-like [Oryzias javanicus] 0.392 0.379 0.406
protein Z-dependent protease inhibitor-like [Oryzias javanicus] 0.355 0.442 0.285
purine nucleoside phosphorylase-like [Oryzias javanicus] 0.221 0.223 0.219
putative monooxygenase p33MONOX-like [Oryzias javanicus] 0.407 0.348 0.476
pyruvate dehydrogenase [lipoamide] kinase isozyme 2-like [Oryzias javanicus] 0.271 0.263 0.279
rab3 GTPase-activating protein non-catalytic subunit-like [Oryzias javanicus] 4.395 3.818 5.059
regulator of G-protein signaling 4-like [Oryzias javanicus] 0.190 0.150 0.239
retinol dehydrogenase 7-like [Oryzias javanicus] 2.256 2.557 1.990
RING finger protein 122-like [Oryzias javanicus] 2.109 1.824 2.438
S-adenosylmethionine synthase isoform type-2-like [Oryzias javanicus] 0.386 0.354 0.420
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform-like isoform X2 [Oryzias javanicus] 0.494 0.459 0.533
serine--pyruvate aminotransferase, mitochondrial-like [Oryzias javanicus] 0.370 0.364 0.376
SH3 domain and tetratricopeptide repeat-containing protein 2-like [Oryzias javanicus] 2.930 2.783 3.085
sodium-coupled neutral amino acid transporter 2-like [Oryzias javanicus] 0.342 0.303 0.387
sodium-dependent phosphate transporter 1-B-like [Oryzias javanicus] 0.309 0.274 0.348
TNFAIP3-interacting protein 1-like [Oryzias javanicus] 2.416 2.217 2.633
translocating chain-associated membrane protein 2-like [Oryzias javanicus] 0.491 0.552 0.437
trimeric intracellular cation channel type A-like [Oryzias javanicus] 0.361 0.291 0.449
tyrosine aminotransferase-like [Oryzias javanicus] 0.258 0.297 0.224
ubiquitin carboxyl-terminal hydrolase 2-like [Oryzias javanicus] 0.283 0.280 0.285
upstream-binding protein 1-like [Oryzias javanicus] 0.290 0.260 0.322
uridine phosphorylase 2-like [Oryzias javanicus] 0.287 0.268 0.308
zinc finger protein 271-like [Oryzias javanicus] 2.310 2.092 2.551
zinc finger protein 521-like [Oryzias javanicus] 0.421 0.515 0.344
zinc finger SWIM domain-containing protein 6-like [Oryzias javanicus] 2.643 2.559 2.729
steroidogenic acute regulatory protein [Oryzias javanicus] 0.113 0.107 0.119
vitellogenin 1 precursor [Oryzias javanicus] 2.155 2.393 1.941
yippee-like b [Oryzias javanicus] 2.262 2.508 2.040

(측정 실험은 3번 반복하여 실시하였고, 측정값이 1보다 작으면 발현량이 감소, 1보다 크면 발현량이 증가한 것이다.)
바다송사리 TCS 24시간 노출군에서 발현량이 2배 이상 변화되는 유전자 목록(60종)
유전자 실험 1 실험 2 실험 3
78 kDa glucose-regulated protein-like precursor [Oryzias javanicus] 0.255 0.232 0.280
choriogenin H precursor [Oryzias javanicus] 0.228 0.229 0.226
histone-lysine N-methyltransferase EZH1-like [Oryzias javanicus] 0.376 0.321 0.441
ketohexokinase [Oryzias javanicus] 0.477 0.478 0.476
L-SF precursor [Oryzias javanicus] 0.205 0.217 0.193
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial-like [Oryzias javanicus] 0.155 0.150 0.159
40S ribosomal protein S9-like isoform 2 [Oryzias javanicus] 2.264 1.837 2.791
ADP-ribosylation factor-like protein 5C-like [Oryzias javanicus] 0.132 0.121 0.143
anti-apoptotic protein NR13-like [Oryzias javanicus] 0.460 0.420 0.504
apoptosis-stimulating of p53 protein 2-like [Oryzias javanicus] 0.374 0.352 0.397
c-C motif chemokine 20-like [Oryzias javanicus] 2.277 2.633 1.970
cholesterol 7-alpha-monooxygenase-like [Oryzias javanicus] 0.317 0.270 0.373
coatomer subunit zeta-2-like isoform X1 [Oryzias javanicus] 0.475 0.488 0.462
complement C3-like [Oryzias javanicus] 2.051 2.146 1.960
cyclin-dependent kinase 4 inhibitor D-like [Oryzias javanicus] 2.299 2.438 2.167
cytochrome c-b-like isoform 1 [Oryzias javanicus] 0.428 0.396 0.462
death domain-associated protein 6-like [Oryzias javanicus] 0.398 0.456 0.347
DNA-binding protein inhibitor ID-1-like [Oryzias javanicus] 2.091 1.992 2.195
dnaJ homolog subfamily C member 15-like isoform X1 [Oryzias javanicus] 0.485 0.524 0.449
elongation of very long chain fatty acids protein 6-like [Oryzias javanicus] 0.375 0.404 0.347
eukaryotic translation initiation factor 4 gamma 2-like, partial [Oryzias javanicus] 0.372 0.382 0.362
fibulin-2-like [Oryzias javanicus] 11.225 8.235 15.300
filamin A-interacting protein 1-like [Oryzias javanicus] 2.732 2.648 2.818
fructose-bisphosphate aldolase A [Oryzias javanicus] 0.244 0.207 0.288
fructose-bisphosphate aldolase A [Oryzias javanicus] 0.249 0.219 0.284
heme oxygenase-like [Oryzias javanicus] 5.975 6.844 5.215
heterogeneous nuclear ribonucleoprotein A/B-like [Oryzias javanicus] 0.371 0.320 0.432
heterogeneous nuclear ribonucleoprotein Q-like [Oryzias javanicus] 0.453 0.456 0.450
inhibin beta B chain-like [Oryzias javanicus] 0.478 0.507 0.451
inter-alpha-trypsin inhibitor heavy chain H3-like [Oryzias javanicus] 2.077 2.168 1.991
kinesin-like protein KIF1A-like [Oryzias javanicus] 2.622 2.854 2.409
leucine--tRNA ligase, cytoplasmic-like [Oryzias javanicus] 0.345 0.301 0.395
motile sperm domain-containing protein 1-like isoform X1 [Oryzias javanicus] 3.713 3.904 3.532
nicotinamide riboside kinase 2-like [Oryzias javanicus] 0.277 0.255 0.301
nuclear distribution protein nudE-like 1-B-like [Oryzias javanicus] 0.347 0.309 0.389
nuclear receptor subfamily 2 group F member 1-A-like isoform X1 [Oryzias javanicus] 2.064 2.181 1.954
nucleoside diphosphate kinase B-like isoform 1 [Oryzias javanicus] 0.454 0.397 0.519
peptidyl-prolyl cis-trans isomerase-like 1-like [Oryzias javanicus] 0.446 0.409 0.486
phosphoribosyl pyrophosphate synthase-associated protein 1-like isoform X3 [Oryzias javanicus] 2.696 3.223 2.254
probable ATP-dependent RNA helicase DDX5-like [Oryzias javanicus] 0.447 0.450 0.445
probable palmitoyltransferase ZDHHC8-like [Oryzias javanicus] 3.028 3.760 2.439
proheparin-binding EGF-like growth factor-like [Oryzias javanicus] 2.497 2.764 2.257
protein disulfide-isomerase A6-like [Oryzias javanicus] 0.475 0.456 0.494
protein FAM13A-like [Oryzias javanicus] 0.474 0.472 0.476
protein phosphatase 1 regulatory subunit 3C-B-like [Oryzias javanicus] 0.455 0.537 0.386
protein phosphatase PTC7 homolog [Oryzias javanicus] 0.396 0.377 0.416
protein transport protein Sec23B-like isoform 2 [Oryzias javanicus] 0.498 0.497 0.498
rab3 GTPase-activating protein non-catalytic subunit-like [Oryzias javanicus] 4.923 5.288 4.584
regulator of G-protein signaling 4-like [Oryzias javanicus] 0.326 0.321 0.332
retinol dehydrogenase 12-like [Oryzias javanicus] 0.334 0.413 0.269
RING finger protein 122-like [Oryzias javanicus] 2.014 1.711 2.369
S-adenosylmethionine synthase isoform type-2-like [Oryzias javanicus] 0.351 0.305 0.404
sodium-dependent phosphate transporter 1-B-like [Oryzias javanicus] 0.463 0.521 0.412
stomatin-like protein 1-like [Oryzias javanicus] 0.426 0.406 0.447
testican-2-like isoform 1 [Oryzias javanicus] 0.498 0.505 0.491
trimeric intracellular cation channel type A-like [Oryzias javanicus] 0.276 0.210 0.362
uridine phosphorylase 2-like [Oryzias javanicus] 0.414 0.347 0.494
zinc finger SWIM domain-containing protein 6-like [Oryzias javanicus] 2.155 2.260 2.056
steroidogenic acute regulatory protein [Oryzias javanicus] 0.119 0.126 0.113
yippee-like b [Oryzias javanicus] 2.407 2.694 2.151

(측정 실험은 3번 반복하여 실시하였고, 측정값이 1보다 작으면 발현량이 감소, 1보다 크면 발현량이 증가한 것이다.)
바다송사리 TCS 48시간 노출군에서 발현량이 2배 이상 변화되는 유전자 목록(61종)
유전자 실험 1 실험 2 실험 3
c-fos protein [Oryzias javanicus] 0.038 0.028 0.051
choriogenin H precursor [Oryzias javanicus] 0.362 0.347 0.379
cytoglobin-1 [Oryzias javanicus] 4.508 4.369 4.651
glyceraldehyde-3-phosphate dehydrogenase, partial [Oryzias javanicus] 0.475 0.547 0.412
immmunoglobulin light chain [Oryzias javanicus] 2.871 2.982 2.764
L-SF precursor [Oryzias javanicus] 0.306 0.332 0.283
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial-like [Oryzias javanicus] 0.450 0.428 0.474
40S ribosomal protein S9-like isoform 2 [Oryzias javanicus] 2.813 2.572 3.077
adenylyl cyclase-associated protein 1-like [Oryzias javanicus] 0.475 0.471 0.480
ADP-ribosylation factor-like protein 5C-like [Oryzias javanicus] 0.168 0.123 0.230
alpha-1-antitrypsin homolog [Oryzias javanicus] 0.456 0.408 0.509
AN1-type zinc finger protein 5-like isoform 1 [Oryzias javanicus] 0.168 0.126 0.222
angiogenin-like isoform X1 [Oryzias javanicus] 2.087 1.796 2.427
ankyrin-3-like [Oryzias javanicus] 0.486 0.507 0.466
apolipoprotein C-II-like isoform X1 [Oryzias javanicus] 2.019 2.282 1.787
apoptosis-stimulating of p53 protein 2-like [Oryzias javanicus] 0.485 0.528 0.446
carbonic anhydrase-related protein-like [Oryzias javanicus] 2.287 2.592 2.017
choline-phosphate cytidylyltransferase A-like [Oryzias javanicus] 0.459 0.493 0.427
coatomer subunit zeta-2-like isoform X1 [Oryzias javanicus] 0.455 0.447 0.462
complement C1q-like protein 2-like [Oryzias javanicus] 0.362 0.298 0.441
cytochrome P450 27C1-like [Oryzias javanicus] 0.350 0.379 0.323
diablo homolog, mitochondrial-like [Oryzias javanicus] 0.323 0.283 0.370
E3 ubiquitin-protein ligase TRIM33-like, partial [Oryzias javanicus] 0.491 0.482 0.500
eukaryotic translation initiation factor 4 gamma 2-like, partial [Oryzias javanicus] 0.414 0.474 0.361
fatty acid-binding protein, heart-like [Oryzias javanicus] 0.477 0.550 0.413
fetuin-B-like [Oryzias javanicus] 0.476 0.571 0.397
fibrinogen alpha chain-like [Oryzias javanicus] 0.410 0.374 0.448
fibulin-2-like [Oryzias javanicus] 9.107 7.260 11.423
filamin A-interacting protein 1-like [Oryzias javanicus] 3.438 2.710 4.361
heme oxygenase-like [Oryzias javanicus] 2.683 3.131 2.300
high mobility group protein HMG-I/HMG-Y-like isoform X1 [Oryzias javanicus] 0.485 0.413 0.570
homeobox protein Hox-A4-like [Oryzias javanicus] 2.192 2.013 2.388
latexin-like [Oryzias javanicus] 0.464 0.437 0.492
LOW QUALITY PROTEIN: glutathione peroxidase 3-like [Oryzias javanicus] 0.493 0.448 0.542
lymphocyte antigen 6D-like [Oryzias javanicus] 2.363 2.423 2.305
motile sperm domain-containing protein 1-like isoform X1 [Oryzias javanicus] 2.349 2.564 2.151
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial-like [Oryzias javanicus] 2.937 3.181 2.711
nicotinamide riboside kinase 2-like [Oryzias javanicus] 0.327 0.362 0.295
nuclear distribution protein nudE-like 1-B-like [Oryzias javanicus] 0.328 0.295 0.365
nuclear receptor subfamily 2 group F member 1-A-like isoform X1 [Oryzias javanicus] 2.592 2.221 3.025
parvalbumin beta-like [Oryzias javanicus] 0.348 0.290 0.418
phosphoribosyl pyrophosphate synthase-associated protein 1-like isoform X3 [Oryzias javanicus] 2.049 2.260 1.858
pleckstrin homology domain-containing family A member 6-like [Oryzias javanicus] 0.330 0.277 0.393
polyadenylate-binding protein 4-like [Oryzias javanicus] 2.541 2.381 2.712
putative all-trans-retinol 13,14-reductase-like [Oryzias javanicus] 0.466 0.468 0.465
rab3 GTPase-activating protein non-catalytic subunit-like [Oryzias javanicus] 4.451 3.660 5.412
ras-related protein Rab-8B-like [Oryzias javanicus] 2.495 3.082 2.019
regulator of G-protein signaling 4-like [Oryzias javanicus] 0.193 0.152 0.246
S-adenosylmethionine synthase isoform type-2-like [Oryzias javanicus] 0.453 0.508 0.405
septin-5-like, partial [Oryzias javanicus] 0.326 0.292 0.364
sodium-coupled neutral amino acid transporter 2-like [Oryzias javanicus] 0.419 0.373 0.470
sphingomyelin phosphodiesterase 2-like [Oryzias javanicus] 2.097 2.273 1.934
sulfotransferase 1C1 [Oryzias javanicus] 0.476 0.424 0.534
testican-2-like isoform 1 [Oryzias javanicus] 0.469 0.407 0.540
TNFAIP3-interacting protein 1-like [Oryzias javanicus] 2.193 2.206 2.180
transcription factor jun-B-like [Oryzias javanicus] 0.475 0.566 0.399
translocating chain-associated membrane protein 2-like [Oryzias javanicus] 0.457 0.470 0.444
UDP-glucuronosyltransferase 2B31-like [Oryzias javanicus] 0.488 0.423 0.563
upstream-binding protein 1-like [Oryzias javanicus] 0.427 0.385 0.473
uridine phosphorylase 2-like [Oryzias javanicus] 0.356 0.313 0.405
steroidogenic acute regulatory protein [Oryzias javanicus] 0.106 0.092 0.121

(측정 실험은 3번 반복하여 실시하였고, 측정값이 1보다 작으면 발현량이 감소, 1보다 크면 발현량이 증가한 것이다.)
바다송사리 TCS 72시간 노출군에서 발현량이 2배 이상 변화되는 유전자 목록(67종)
유전자 실험 1 실험 2 실험 3
annexin max3 [Oryzias javanicus] 0.390 0.418 0.363
choriogenin H precursor [Oryzias javanicus] 0.210 0.260 0.170
histone-lysine N-methyltransferase EZH1-like [Oryzias javanicus] 0.403 0.328 0.495
L-SF precursor [Oryzias javanicus] 0.226 0.259 0.198
phosphatase and actin regulator 3 [Oryzias javanicus] 0.334 0.313 0.356
15-hydroxyprostaglandin dehydrogenase [NAD(+)]-like [Oryzias javanicus] 0.282 0.341 0.233
abnormal spindle-like microcephaly-associated protein homolog [Oryzias javanicus] 0.436 0.435 0.438
adenylyl cyclase-associated protein 1-like [Oryzias javanicus] 0.379 0.313 0.460
AN1-type zinc finger protein 5-like isoform 1 [Oryzias javanicus] 0.317 0.345 0.291
angiogenin-like [Oryzias javanicus] 3.140 2.822 3.493
angiogenin-like isoform X1 [Oryzias javanicus] 3.829 3.592 4.082
cardiomyopathy-associated protein 5-like isoform X4 [Oryzias javanicus] 2.004 2.398 1.674
cell division control protein 42 homolog isoform X4 [Oryzias javanicus] 2.040 2.361 1.762
charged multivesicular body protein 6-like [Oryzias javanicus] 2.275 2.422 2.137
cholesterol 7-alpha-monooxygenase-like [Oryzias javanicus] 0.453 0.504 0.406
CLK4-associating serine/arginine rich protein-like [Oryzias javanicus] 2.201 2.592 1.870
coatomer subunit zeta-2-like isoform X1 [Oryzias javanicus] 0.472 0.515 0.432
coiled-coil domain-containing protein 43-like isoform 1 [Oryzias javanicus] 0.391 0.367 0.417
complement C1q-like protein 2-like [Oryzias javanicus] 0.172 0.202 0.147
complement C1q-like protein 2-like [Oryzias javanicus] 0.147 0.159 0.136
CREB/ATF bZIP transcription factor-like [Oryzias javanicus] 0.462 0.457 0.467
cytochrome c-b-like isoform 1 [Oryzias javanicus] 0.497 0.458 0.540
diacylglycerol O-acyltransferase 2-like [Oryzias javanicus] 2.058 2.171 1.951
disintegrin and metalloproteinase domain-containing protein 12-like [Oryzias javanicus] 2.153 2.550 1.818
DNA damage-inducible transcript 4 protein-like [Oryzias javanicus] 0.409 0.469 0.357
dnaJ homolog subfamily C member 15-like isoform X1 [Oryzias javanicus] 0.471 0.513 0.433
eukaryotic translation initiation factor 4 gamma 2-like, partial [Oryzias javanicus] 0.366 0.396 0.339
fatty acid-binding protein, heart-like [Oryzias javanicus] 0.491 0.562 0.429
ferritin, heavy subunit-like isoform X1 [Oryzias javanicus] 0.386 0.437 0.340
fetuin-B-like [Oryzias javanicus] 2.057 2.430 1.741
fibulin-2-like [Oryzias javanicus] 7.156 6.595 7.765
fructose-bisphosphate aldolase A [Oryzias javanicus] 0.233 0.191 0.285
fructose-bisphosphate aldolase A [Oryzias javanicus] 0.252 0.210 0.302
gap junction Cx32.2 protein-like [Oryzias javanicus] 0.493 0.515 0.473
gelsolin-like [Oryzias javanicus] 0.394 0.340 0.455
homeobox protein Hox-A4-like [Oryzias javanicus] 2.059 2.009 2.111
intraflagellar transport protein 20 homolog isoform 1 [Oryzias javanicus] 0.475 0.521 0.434
LYR motif-containing protein 5A-like isoform X1 [Oryzias javanicus] 0.422 0.375 0.475
myosin heavy chain, fast skeletal muscle-like, partial [Oryzias javanicus] 2.037 2.262 1.834
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial-like [Oryzias javanicus] 2.294 2.040 2.580
NEDD4-like E3 ubiquitin-protein ligase WWP1-like [Oryzias javanicus] 2.109 2.353 1.891
nicotinamide riboside kinase 2-like [Oryzias javanicus] 0.300 0.344 0.263
nuclear receptor subfamily 2 group F member 1-A-like isoform X1 [Oryzias javanicus] 2.502 2.493 2.512
p21-activated protein kinase-interacting protein 1-like [Oryzias javanicus] 0.407 0.435 0.381
pancreatic progenitor cell differentiation and proliferation factor A-like isoform 1 [Oryzias javanicus] 0.457 0.378 0.552
peroxisomal 2,4-dienoyl-CoA reductase-like [Oryzias javanicus] 0.430 0.363 0.509
phosphatidylinositol 5-phosphate 4-kinase type-2 beta-like isoform 2 [Oryzias javanicus] 2.354 2.879 1.925
phosphatidylserine synthase 1-like [Oryzias javanicus] 0.480 0.473 0.487
phosphoribosyl pyrophosphate synthase-associated protein 1-like isoform X3 [Oryzias javanicus] 2.092 2.514 1.741
plexin-A4-like, partial [Oryzias javanicus] 2.289 2.422 2.164
poly(ADP-ribose) glycohydrolase ARH3-like [Oryzias javanicus] 2.406 2.033 2.848
probable ATP-dependent RNA helicase DDX27-like [Oryzias javanicus] 0.386 0.345 0.433
protein Z-dependent protease inhibitor-like [Oryzias javanicus] 0.407 0.454 0.365
rab3 GTPase-activating protein non-catalytic subunit-like [Oryzias javanicus] 4.332 4.116 4.560
regulator of G-protein signaling 4-like [Oryzias javanicus] 0.170 0.143 0.202
retinol dehydrogenase 7-like [Oryzias javanicus] 2.525 2.724 2.340
sestrin-1-like isoform 2 [Oryzias javanicus] 0.376 0.342 0.413
sulfotransferase 1C1 [Oryzias javanicus] 0.427 0.355 0.513
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1-like isoform X1 [Oryzias javanicus] 2.786 3.533 2.197
trafficking protein particle complex subunit 6B-like isoform 1 [Oryzias javanicus] 0.437 0.442 0.432
translation initiation factor eIF-2B subunit gamma-like [Oryzias javanicus] 0.314 0.250 0.394
translocating chain-associated membrane protein 2-like [Oryzias javanicus] 0.487 0.494 0.480
ubiquitin carboxyl-terminal hydrolase 2-like [Oryzias javanicus] 0.456 0.405 0.514
ubiquitin-conjugating enzyme E2 A-like isoform X1 [Oryzias javanicus] 0.500 0.486 0.515
ubiquitin-conjugating enzyme E2 G1-like [Oryzias javanicus] 0.435 0.547 0.346
upstream-binding protein 1-like [Oryzias javanicus] 0.345 0.370 0.321
zinc finger and BTB domain-containing protein 1-like [Oryzias javanicus] 0.156 0.176 0.138

(측정 실험은 3번 반복하여 실시하였고, 측정값이 1보다 작으면 발현량이 감소, 1보다 크면 발현량이 증가한 것이다.)
바다송사리 TCS 노출군에서 발현량이 2배 이상 감소되는 유전자 목록(125종)
서열번호 유전자 실험 1 실험 2 실험 3
1 dimethylglycine dehydrogenase, mitochondrial-like [Oryzias javanicus] 0.500 0.571 0.438
2 phosphatase and actin regulator 3 [Oryzias javanicus] 0.334 0.313 0.356
3 ankyrin-3-like [Oryzias javanicus] 0.486 0.507 0.466
4 coiled-coil domain-containing protein 43-like isoform 1 [Oryzias javanicus] 0.469 0.414 0.531
5 peptidyl-prolyl cis-trans isomerase-like 1-like [Oryzias javanicus] 0.446 0.409 0.486
6 abnormal spindle-like microcephaly-associated protein homolog [Oryzias javanicus] 0.436 0.435 0.438
7 zinc finger protein 521-like [Oryzias javanicus] 0.421 0.515 0.344
8 testican-2-like isoform 1 [Oryzias javanicus] 0.498 0.505 0.491
9 E3 ubiquitin-protein ligase TRIM33-like, partial [Oryzias javanicus] 0.435 0.469 0.403
10 transcription factor jun-B-like [Oryzias javanicus] 0.475 0.566 0.399
11 diablo homolog, mitochondrial-like [Oryzias javanicus] 0.323 0.283 0.370
12 ADP-ribosylation factor-like protein 5C-like [Oryzias javanicus] 0.082 0.060 0.113
13 regulator of G-protein signaling 4-like [Oryzias javanicus] 0.190 0.150 0.239
14 translocating chain-associated membrane protein 2-like [Oryzias javanicus] 0.491 0.552 0.437
15 fetuin-B-like [Oryzias javanicus] 0.476 0.571 0.397
16 S-adenosylmethionine synthase isoform type-2-like [Oryzias javanicus] 0.386 0.354 0.420
17 choriogenin H precursor [Oryzias javanicus] 0.228 0.229 0.226
18 nocturnin-like [Oryzias javanicus] 0.194 0.153 0.244
19 trafficking protein particle complex subunit 6B-like isoform 1 [Oryzias javanicus] 0.437 0.442 0.432
20 translation initiation factor eIF-2B subunit gamma-like [Oryzias javanicus] 0.314 0.250 0.394
21 anti-apoptotic protein NR13-like [Oryzias javanicus] 0.382 0.339 0.431
22 cytochrome c-b-like isoform 1 [Oryzias javanicus] 0.428 0.396 0.462
23 trimeric intracellular cation channel type A-like [Oryzias javanicus] 0.276 0.210 0.362
24 apoptosis-stimulating of p53 protein 2-like [Oryzias javanicus] 0.374 0.352 0.397
25 fructose-bisphosphate aldolase A [Oryzias javanicus] 0.233 0.191 0.285
26 baculoviral IAP repeat-containing protein 2-like isoform X5 [Oryzias javanicus] 0.472 0.449 0.497
27 sestrin-1-like isoform 2 [Oryzias javanicus] 0.376 0.342 0.413
28 pleckstrin homology domain-containing family A member 6-like [Oryzias javanicus] 0.386 0.389 0.383
29 retinol dehydrogenase 12-like [Oryzias javanicus] 0.334 0.413 0.269
30 apolipoprotein A-IV-like [Oryzias javanicus] 0.468 0.532 0.412
31 hepcidin-like [Oryzias javanicus] 0.293 0.352 0.244
32 c-fos protein [Oryzias javanicus] 0.034 0.021 0.058
33 cytochrome P450 2P3 [Oryzias javanicus] 0.486 0.475 0.498
34 alpha-1-antitrypsin homolog [Oryzias javanicus] 0.456 0.408 0.509
35 ketohexokinase-like [Oryzias javanicus] 0.320 0.359 0.285
36 inhibin beta B chain-like [Oryzias javanicus] 0.478 0.507 0.451
37 glyceraldehyde-3-phosphate dehydrogenase, partial [Oryzias javanicus] 0.475 0.547 0.412
38 nucleolar protein 58-like [Oryzias javanicus] 0.337 0.303 0.375
39 FAST kinase domain-containing protein 3-like [Oryzias javanicus] 0.461 0.495 0.429
40 ADP-ribosylation factor-like protein 5C-like [Oryzias javanicus] 0.132 0.121 0.143
41 nicotinamide riboside kinase 2-like [Oryzias javanicus] 0.300 0.344 0.263
42 p21-activated protein kinase-interacting protein 1-like [Oryzias javanicus] 0.456 0.528 0.393
43 dnaJ homolog subfamily C member 15-like isoform X1 [Oryzias javanicus] 0.281 0.324 0.245
44 LYR motif-containing protein 5A-like isoform X1 [Oryzias javanicus] 0.422 0.375 0.475
45 fatty acid-binding protein, heart-like [Oryzias javanicus] 0.477 0.550 0.413
46 complement C1q-like protein 2-like [Oryzias javanicus] 0.147 0.159 0.136
47 CREB/ATF bZIP transcription factor-like [Oryzias javanicus] 0.462 0.457 0.467
48 phosphatidylserine synthase 1-like [Oryzias javanicus] 0.480 0.473 0.487
49 parvalbumin beta-like [Oryzias javanicus] 0.348 0.290 0.418
50 ketohexokinase-like isoform X3 [Oryzias javanicus] 0.299 0.307 0.292
51 cytochrome P450 27C1-like [Oryzias javanicus] 0.350 0.379 0.323
52 erythrocyte band 7 integral membrane protein-like [Oryzias javanicus] 0.316 0.308 0.324
53 sodium-coupled neutral amino acid transporter 2-like [Oryzias javanicus] 0.342 0.303 0.387
54 serine--pyruvate aminotransferase, mitochondrial-like [Oryzias javanicus] 0.370 0.364 0.376
55 zinc finger and BTB domain-containing protein 1-like [Oryzias javanicus] 0.156 0.176 0.138
56 putative monooxygenase p33MONOX-like [Oryzias javanicus] 0.407 0.348 0.476
57 ketohexokinase [Oryzias javanicus] 0.287 0.317 0.259
58 nucleoside diphosphate kinase B-like isoform 1 [Oryzias javanicus] 0.454 0.397 0.519
59 complement C1q-like protein 2-like [Oryzias javanicus] 0.362 0.298 0.441
60 putative all-trans-retinol 13,14-reductase-like [Oryzias javanicus] 0.466 0.468 0.465
61 mitochondrial import receptor subunit TOM40 homolog [Oryzias javanicus] 0.443 0.370 0.529
62 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform-like isoform X2 [Oryzias javanicus] 0.494 0.459 0.533
63 nuclear distribution protein nudE-like 1-B-like [Oryzias javanicus] 0.224 0.231 0.218
64 fructose-bisphosphate aldolase A [Oryzias javanicus] 0.252 0.210 0.302
65 annexin max3 [Oryzias javanicus] 0.487 0.521 0.455
66 dipeptidase 1-like [Oryzias javanicus] 0.210 0.248 0.179
67 L-SF precursor [Oryzias javanicus] 0.205 0.217 0.193
68 ubiquitin-conjugating enzyme E2 G1-like [Oryzias javanicus] 0.435 0.547 0.346
69 stomatin-like protein 1-like [Oryzias javanicus] 0.426 0.406 0.447
70 fibrinogen alpha chain-like [Oryzias javanicus] 0.410 0.374 0.448
71 sulfotransferase 1C1 [Oryzias javanicus] 0.476 0.424 0.534
72 uridine phosphorylase 2-like [Oryzias javanicus] 0.356 0.313 0.405
73 cytochrome P450 2J6-like isoform 1 [Oryzias javanicus] 0.484 0.441 0.530
74 proline synthase co-transcribed bacterial homolog protein-like [Oryzias javanicus] 0.366 0.375 0.357
75 protein phosphatase 1 regulatory subunit 3C-B-like [Oryzias javanicus] 0.455 0.537 0.386
76 purine nucleoside phosphorylase-like [Oryzias javanicus] 0.221 0.223 0.219
77 DNA damage-inducible transcript 4 protein-like [Oryzias javanicus] 0.409 0.469 0.357
78 probable ATP-dependent RNA helicase DDX27-like [Oryzias javanicus] 0.386 0.345 0.433
79 heterogeneous nuclear ribonucleoprotein Q-like [Oryzias javanicus] 0.496 0.479 0.513
80 ligand of Numb protein X 2-like [Oryzias javanicus] 0.439 0.418 0.461
81 protein Tob1-like [Oryzias javanicus] 0.392 0.379 0.406
82 histone-lysine N-methyltransferase EZH1-like [Oryzias javanicus] 0.464 0.533 0.405
83 protein FAM13A-like [Oryzias javanicus] 0.474 0.472 0.476
84 elongation of very long chain fatty acids protein 6-like [Oryzias javanicus] 0.375 0.404 0.347
85 p21-activated protein kinase-interacting protein 1-like [Oryzias javanicus] 0.407 0.435 0.381
86 ubiquitin-conjugating enzyme E2 A-like isoform X1 [Oryzias javanicus] 0.500 0.486 0.515
87 upstream-binding protein 1-like [Oryzias javanicus] 0.290 0.260 0.322
88 death domain-associated protein 6-like [Oryzias javanicus] 0.443 0.452 0.434
89 palmitoyl-protein thioesterase 1-like [Oryzias javanicus] 0.378 0.404 0.354
90 cholesterol 7-alpha-monooxygenase-like [Oryzias javanicus] 0.334 0.325 0.344
91 ferritin, heavy subunit-like isoform X1 [Oryzias javanicus] 0.386 0.437 0.340
92 septin-5-like, partial [Oryzias javanicus] 0.326 0.292 0.364
93 gap junction Cx32.2 protein-like [Oryzias javanicus] 0.390 0.470 0.324
94 tyrosine aminotransferase-like [Oryzias javanicus] 0.258 0.297 0.224
95 AN1-type zinc finger protein 5-like isoform 1 [Oryzias javanicus] 0.086 0.079 0.093
96 peroxisomal 2,4-dienoyl-CoA reductase-like [Oryzias javanicus] 0.430 0.363 0.509
97 eukaryotic translation initiation factor 4 gamma 2-like, partial [Oryzias javanicus] 0.298 0.262 0.338
98 adenylyl cyclase-associated protein 1-like [Oryzias javanicus] 0.379 0.313 0.460
99 mid1-interacting protein 1-like isoform 1 [Oryzias javanicus] 0.365 0.308 0.431
100 pyruvate dehydrogenase [lipoamide] kinase isozyme 2-like [Oryzias javanicus] 0.271 0.263 0.279
101 LOW QUALITY PROTEIN: glutathione peroxidase 3-like [Oryzias javanicus] 0.493 0.448 0.542
102 ubiquitin carboxyl-terminal hydrolase 2-like [Oryzias javanicus] 0.283 0.280 0.285
103 latexin-like [Oryzias javanicus] 0.464 0.437 0.492
104 high mobility group protein HMG-I/HMG-Y-like isoform X1 [Oryzias javanicus] 0.385 0.398 0.373
105 coatomer subunit zeta-2-like isoform X1 [Oryzias javanicus] 0.472 0.515 0.432
106 gelsolin-like [Oryzias javanicus] 0.394 0.340 0.455
107 15-hydroxyprostaglandin dehydrogenase [NAD(+)]-like [Oryzias javanicus] 0.282 0.341 0.233
108 probable ATP-dependent RNA helicase DDX5-like [Oryzias javanicus] 0.446 0.486 0.409
109 choline-phosphate cytidylyltransferase A-like [Oryzias javanicus] 0.459 0.493 0.427
110 anti-apoptotic protein NR13-like [Oryzias javanicus] 0.460 0.420 0.504
111 sodium-dependent phosphate transporter 1-B-like [Oryzias javanicus] 0.309 0.274 0.348
112 steroidogenic acute regulatory protein [Oryzias javanicus] 0.106 0.092 0.121
113 cytochrome P450 2D10-like isoform 1 [Oryzias javanicus] 0.398 0.383 0.414
114 78 kDa glucose-regulated protein-like precursor [Oryzias javanicus] 0.255 0.232 0.280
115 heterogeneous nuclear ribonucleoprotein A/B-like [Oryzias javanicus] 0.242 0.234 0.249
116 pre-rRNA-processing protein TSR1 homolog [Oryzias javanicus] 0.498 0.460 0.540
117 UDP-glucuronosyltransferase 2B31-like [Oryzias javanicus] 0.488 0.423 0.563
118 pancreatic progenitor cell differentiation and proliferation factor A-like isoform 1 [Oryzias javanicus] 0.457 0.378 0.552
119 protein transport protein Sec23B-like isoform 2 [Oryzias javanicus] 0.498 0.497 0.498
120 intraflagellar transport protein 20 homolog isoform 1 [Oryzias javanicus] 0.475 0.521 0.434
121 protein disulfide-isomerase A6-like [Oryzias javanicus] 0.475 0.456 0.494
122 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial-like [Oryzias javanicus] 0.155 0.150 0.159
123 leucine--tRNA ligase, cytoplasmic-like [Oryzias javanicus] 0.345 0.301 0.395
124 protein Z-dependent protease inhibitor-like [Oryzias javanicus] 0.355 0.442 0.285
125 protein phosphatase PTC7 homolog [Oryzias javanicus] 0.396 0.377 0.416

(측정 실험은 3번 반복하여 실시하였고, 측정값이 1보다 작으면 발현량이 감소, 1보다 크면 발현량이 증가한 것이다.)
바다송사리 TCS 노출군에서 발현량이 2배 이상 증가되는 유전자 목록(58종)
서열번호 유전자 실험 1 실험 2 실험 3
126 polyadenylate-binding protein 4-like [Oryzias javanicus] 2.541 2.381 2.712
127 filamin A-interacting protein 1-like [Oryzias javanicus] 2.768 2.985 2.568
128 proheparin-binding EGF-like growth factor-like [Oryzias javanicus] 2.497 2.764 2.257
129 lymphocyte antigen 6D-like [Oryzias javanicus] 2.363 2.423 2.305
130 kinesin-like protein KIF1A-like [Oryzias javanicus] 2.622 2.854 2.409
131 fibulin-2-like [Oryzias javanicus] 11.190 10.353 12.094
132 motile sperm domain-containing protein 1-like isoform X1 [Oryzias javanicus] 2.120 1.840 2.443
133 SH3 domain and tetratricopeptide repeat-containing protein 2-like [Oryzias javanicus] 2.930 2.783 3.085
134 nuclear receptor subfamily 1 group D member 1-like [Oryzias javanicus] 2.198 2.449 1.972
135 phosphatidylinositol 5-phosphate 4-kinase type-2 beta-like isoform 2 [Oryzias javanicus] 2.354 2.879 1.925
136 disintegrin and metalloproteinase domain-containing protein 12-like [Oryzias javanicus] 2.099 2.154 2.045
137 inter-alpha-trypsin inhibitor heavy chain H3-like [Oryzias javanicus] 2.077 2.168 1.991
138 diacylglycerol O-acyltransferase 2-like [Oryzias javanicus] 2.058 2.171 1.951
139 myosin heavy chain, fast skeletal muscle-like, partial [Oryzias javanicus] 2.037 2.262 1.834
140 rab3 GTPase-activating protein non-catalytic subunit-like [Oryzias javanicus] 4.395 3.818 5.059
141 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1-like isoform X1 [Oryzias javanicus] 2.786 3.533 2.197
142 poly(ADP-ribose) glycohydrolase ARH3-like [Oryzias javanicus] 2.406 2.033 2.848
143 cell division control protein 42 homolog isoform X4 [Oryzias javanicus] 2.040 2.361 1.762
144 fructose-bisphosphate aldolase B [Oryzias javanicus] 2.551 2.877 2.263
145 cardiomyopathy-associated protein 5-like isoform X4 [Oryzias javanicus] 2.004 2.398 1.674
146 fetuin-B-like [Oryzias javanicus] 2.057 2.430 1.741
147 angiogenin-like isoform X1 [Oryzias javanicus] 2.087 1.796 2.427
148 40S ribosomal protein S9-like isoform 2 [Oryzias javanicus] 2.813 2.572 3.077
149 angiogenin-like [Oryzias javanicus] 3.140 2.822 3.493
150 phosphatidylinositol 3-kinase regulatory subunit gamma-like [Oryzias javanicus] 2.414 2.615 2.229
151 ras-related protein Rab-8B-like [Oryzias javanicus] 2.495 3.082 2.019
152 zinc finger protein 271-like [Oryzias javanicus] 2.310 2.092 2.551
153 immmunoglobulin light chain [Oryzias javanicus] 2.871 2.982 2.764
154 complement C3-like [Oryzias javanicus] 2.051 2.146 1.960
155 vitellogenin 1 precursor [Oryzias javanicus] 2.155 2.393 1.941
156 NEDD4-like E3 ubiquitin-protein ligase WWP1-like [Oryzias javanicus] 2.109 2.353 1.891
157 TNFAIP3-interacting protein 1-like [Oryzias javanicus] 2.416 2.217 2.633
158 phosphoribosyl pyrophosphate synthase-associated protein 1-like isoform X3 [Oryzias javanicus] 2.591 2.656 2.527
159 arrestin domain-containing protein 3-like isoform 1 [Oryzias javanicus] 2.073 2.271 1.893
160 sphingomyelin phosphodiesterase 2-like [Oryzias javanicus] 2.097 2.273 1.934
161 polypyrimidine tract-binding protein 1-like [Oryzias javanicus] 2.147 2.467 1.868
162 c-C motif chemokine 20-like [Oryzias javanicus] 2.277 2.633 1.970
163 RING finger protein 122-like [Oryzias javanicus] 2.109 1.824 2.438
164 cyclin-dependent kinase 4 inhibitor D-like [Oryzias javanicus] 2.299 2.438 2.167
165 lysine-specific histone demethylase 1B-like [Oryzias javanicus] 2.103 1.985 2.229
166 cytoglobin-1 [Oryzias javanicus] 4.384 3.350 5.738
167 yippee-like b [Oryzias javanicus] 2.407 2.694 2.151
168 interleukin-1 receptor-like 2-like [Oryzias javanicus] 2.165 2.617 1.791
169 DNA-binding protein inhibitor ID-1-like [Oryzias javanicus] 2.254 2.290 2.218
170 probable palmitoyltransferase ZDHHC8-like [Oryzias javanicus] 3.028 3.760 2.439
171 plexin-A4-like, partial [Oryzias javanicus] 2.289 2.422 2.164
172 homeobox protein Hox-A4-like [Oryzias javanicus] 2.192 2.013 2.388
173 E3 ubiquitin-protein ligase ZNRF2-like [Oryzias javanicus] 2.223 2.361 2.093
174 charged multivesicular body protein 6-like [Oryzias javanicus] 2.010 1.955 2.066
175 apolipoprotein C-II-like isoform X1 [Oryzias javanicus] 8.319 7.374 9.386
176 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial-like [Oryzias javanicus] 2.937 3.181 2.711
177 lysine-specific demethylase 5B-like [Oryzias javanicus] 2.149 1.920 2.406
178 retinol dehydrogenase 7-like [Oryzias javanicus] 2.256 2.557 1.990
179 heme oxygenase-like [Oryzias javanicus] 2.683 3.131 2.300
180 zinc finger SWIM domain-containing protein 6-like [Oryzias javanicus] 2.643 2.559 2.729
181 nuclear receptor subfamily 2 group F member 1-A-like isoform X1 [Oryzias javanicus] 2.502 2.493 2.512
182 CLK4-associating serine/arginine rich protein-like [Oryzias javanicus] 2.201 2.592 1.870
183 carbonic anhydrase-related protein-like [Oryzias javanicus] 2.287 2.592 2.017

(측정 실험은 3번 반복하여 실시하였고, 측정값이 1보다 작으면 발현량이 감소, 1보다 크면 발현량이 증가한 것이다.)
본 발명에서 제시한 트리클로산(triclosan; TCS) 노출에 대응하는 바다송사리(Oryzias javanicus)의 유전자는 수생태계의 내분비계장애물질 오염 및 이에 따른 수생태계의 상황을 모니터링하고 진단하기 위한 바이오센서의 성분으로 유용하게 사용될 수 있다. 아울러, 제시된 유전자들의 기능에 의거하여 본 생물의 대사/생리변화를 구체화함으로써 앞으로 일어날 수도 있는 병리적 현상을 예측할 수 있는 생체지표 및 센서로 이용할 수 있으며, 수생태계의 스트레스원 검출 또는 건강 진단방법에 효과적으로 이용될 수 있다.
<110> Korea Institute of Ocean Science and Technology <120> Triclosan responsive genes in Oryzias javanicus and the method for diagnosing aquatic environment pollution using the same <130> 16P-01-017 <160> 183 <170> KoPatentIn 3.0 <210> 1 <211> 707 <212> DNA <213> Oryzias javanicus <400> 1 ggacccgcgg gcagggagtg caagctggtg atggagaaag tagggggtga tcgacctcac 60 gccttttggt aagttcacgg tgaaggggaa ggactcgctc aagctgctgg accgcctgtt 120 tgccaacacc atgccgaagg tgggtcagac gaacatcagc cacatgctga ccccttcagg 180 gaaagtctac gccgaggtca ccatcaccca gctgactccg ggagagttcc tgctcatcac 240 gggatcgggc tcagagctcc acgacctcag gtggattgaa gcagaagcag accgcggata 300 cgaggtggag atcagaaacg tcacggacga gatcggcgtg ctcggcatcg ccgggccaaa 360 ctcccggagc gttttacaaa agctgaccag cgaggattta agcgacgccg cgttcaagtt 420 tctgcagtgc aagtccatcc agctggccgg ggctcccgta cgggccatca ggatctccta 480 caccggggag cttggctggg agttgtacat ggagcaggag aacatggcgg cggtttatca 540 ggccatgatg gaggcgggaa aggatcaggg gattgacaac tttggaacct acgccatggc 600 gtcactcaga ctggagaagg gcttcagggg ctggggggcc gagatgaact gtgacaccaa 660 tcctctggag gccggtctgg attacttcat caagctaaac aagcccg 707 <210> 2 <211> 708 <212> DNA <213> Oryzias javanicus <400> 2 gcagacgtcg gacgagcgct gtccggcggg ccgaggcccc atccacagat tttagcaact 60 cttcacagaa gaaaccttgc taaggtcggt ggaacctggt cagatgcttg ctggaggagt 120 ggacttccat ctcgttgctt ttgaactcgt tcagctcttt cctgatggcc gccttgtcgg 180 cggcggacag tctcgtccag ggtttgtcgg cgcgccggtc gtagtcctga gctttggcca 240 cctccacgta atcactgaag cggatcagga tctttctttc tcgcagctcg tccaccgtcg 300 gccgctggtt gagctttcgg tttagtcgct gcttgatttc cctcctctcc tcctgctcag 360 tctgatcatt tctctgcttg aggatgttgc ggctctccag ctcctccacc gcgggtctct 420 ggctcagcct cctgcggaag aacaccagaa tgacgttctg aaccatgttt acggccgcgc 480 ggcgtccgcc gagagccgga gcacagagcg ccgagatccg cgcatccaag cgccgaagcg 540 cgcgcctctc ctcgcgtgca cacagcggct accgtcggcg ttacaacatc cgaaactcca 600 cattgggata agaagaccgc aaaggagccg gttcggacgg gggagaaact ttcccagaag 660 ctccgcggag ctgtagcgct gcagcggcga ggagtggcga ggagcggc 708 <210> 3 <211> 2040 <212> DNA <213> Oryzias javanicus <400> 3 cgaagagtat ctgagagatc ggtctcgctt tcattcacca gacagaagca gttacagtga 60 aggtaggtca gctgcaccaa gaacagagta cgtttttagg tcatcaagaa atgcctatga 120 tcagtctggg cgcttggcca atgttgatga taactttgac aaattgacac ttctgcagta 180 ttcatctgag cctggtagtc caaaacattc tgtttggatg cgtgtgtccg atgacactca 240 aaataatgac ggcgggcaaa taatgtacga ggacagagtt gacaggactg ttaaagaggc 300 agaggagaaa ctgagtgaag tgtctcagtt ctttagggat aaaacagagc aactcaatga 360 tgaactatca tctccagaaa aaaaatctcg caggccagac ttcagggaat cgcgatcagg 420 gcccagttca acacaaagta gcccagagag gtcaccatat aggactgggt gtagtgggga 480 agaatggaat agagaaagac ttcgagacag gtttgcctca agtgacagaa aatgtgccag 540 tttacctagt agcccagaac ggagagcatt gctgcagttt tctgatgcag attcccaaaa 600 acagagaggt gatacatcac agagaaatgc tggtgataac cctaaatctc ctcaaatgtc 660 atcatccaaa gtcagtgcag tgcgactgaa gtttgagcaa gaggctcaaa gacaacagag 720 gagtcctcag ggtggccaaa attccaatct tccagttagg aaactccaag aaactaaact 780 accagtgtat cagatgtttg gtggaagtag cgtttcaaaa actccagata gtccagtaac 840 tcagagaaaa ggcattggca atgattcaaa tacattttct cccaaacatg aaaccagtga 900 aaaagagaaa aatcaggaag aaagcacctt gttcaaaact agggatggcc aaaggtatgg 960 gcatcacaac cctcaatctc ccaaattatc ccattcttca gtccatgatt cgccaaatga 1020 tttcaataaa agtgattcgc aaagacagga agcagctaag aaagtagtct acacagaata 1080 tgtggtcaga gaaagtccaa aattgcaaca gtagtctaaa aaaaactcgg aatcacaaat 1140 tcctgtaaaa aagtcatcta atttcccaga aaaacagaaa tcttctccat atttaatgtt 1200 agatgaatct cacgaaagat ctgggtctcg tacagctatt tcagctagaa atcagtccaa 1260 aagtagctcc gaatccaata agtctactcg aggtttatca gtcggaaaat ctacgccaga 1320 cacgagccag tccaatgtgt tgtgtaatgg tgtggatgat gaccaggtgg agtatttggg 1380 tcaagtaaca cctgtggtca taactgaagg tttcaaggat attaaaccat tgcctgtgta 1440 tgtcagcatt caagtaggaa agcagtatga aaaagaggaa gcctcggggc agctaggaac 1500 atataaaaag atagtaagcc acgagagtag gacagtccac gagactaggg gtgcatttta 1560 cactgtcaaa caaaagcagt ctccatctcc tcaaggaagt ccagaagatg acactctgga 1620 acaagtgact ttcatggaca gctctggccg aagtcctgtt actcctgaga ctccaagctc 1680 ggaggaaatg agtcttacct ccagagcccc agactctgtg ataggcttca tgactggtat 1740 gccaagccct attccagagg agtctgaaga agaagagggg aagaccttca tctataagga 1800 gccctctaaa gaaaaatcaa agccagcttc tcctgaaatt cgcagtaaaa atcaagatgg 1860 agagagaagg aagtcaggag aaaaaagagt tgcttatata gagtttccac cacctccccc 1920 cttagaggca gagcagtctg atcctaagaa aaagggttcc cagggttcct ctgaagcaga 1980 gaccgaaatg atggaggtaa atctccaaga ggagcatgat aggcacctcc tatctgaacc 2040 2040 <210> 4 <211> 702 <212> DNA <213> Oryzias javanicus <400> 4 aagcagtggt atcaacgcag agtggccatt acggccgggg acagcgccaa gatggcggcg 60 cccttgtcag acgccgggga gtttgaaatc tggttaaatg agcgattaga taatctggaa 120 gtggatcgag aggtgtacgg ggcttacatt ttggggattc tacaagaaga agaaaatgac 180 gaggagaagg aagacgctct tcgcgggatt ttatcggcgt ttctggaaga ggatgccatg 240 gaagatgtct gcaaacagat catccagcag tgggcagact attccagccg atcagcagcc 300 atgaaaaatg cagatgatgc tgaggtccag gccatcgcca gcatgataga aaagcaagcg 360 cagatcgtgg tgaaacagaa ggaggtctct gaggagtcaa agaagaggaa ggaggctcta 420 ctggctcaat atgccaacat aacagacgag gaggatgaag ctgaagaaga ggagcctgca 480 ggtggaaacg acatcgctgc aaatgaaaga tccctgttca agaacaccaa cgtggaggag 540 gtgctccaca gacagaagca gaagcgggaa caggcccggg aagacgctca gaagaagaaa 600 gaaacggaca agatgcagcg agagaaggac aagctggcca agcaggacag gaaggagaag 660 gagaagaagc gcacacagaa aaatgaacgg cgaagataaa ac 702 <210> 5 <211> 674 <212> DNA <213> Oryzias javanicus <400> 5 aagcagtggt atcaacgcag agtggccatt acggccgggg aaagtagaag aagaatttcc 60 tgtttgaatt tgctgaatga actctttaga aatagtaatc gctggtttta aattacactt 120 tatttgtacc gtttgttgta aagtttgcat tttggagtcg taatgtccgg aatacctcca 180 gatacgtggc agccgcccac cgtcgccgtg gaaaccacga tggggacgct tgtggtggag 240 ctgtactgga atcatgcccc gaaaacatgc aagaacttcg cagaactcgc caggagggga 300 tactacaacg ataccaggtt tcaccggata attaaagact tcatggttca gtgtggagat 360 cctacaggaa caggtcgagg aggcgcgtcc atatttggta aacagtttga agatgagctt 420 catccagagc tgaagttcac aggtgctgga attctagcga tggcgaacgc tggaccggac 480 accaacggaa gtcagttctt cctcacgctg gcgcccactc agtggctgga cgggaagcac 540 agcatcttcg ggcgagtgtg tcagggcatc ggagtgctga accgcatcgg gatggtggag 600 acagacagtc aagaccgtcc cactgatgac ataaggattc ttcgaacaac tttgccaaat 660 tagacttttt tttt 674 <210> 6 <211> 656 <212> DNA <213> Oryzias javanicus <400> 6 tgacattaaa gtcctcagta cagaagattc agcgcagata tcgagccaac atggcgcaaa 60 gaaacaaaaa taccaatatc aacaaatcag aaaagcagca atcctcctgc aggccgccta 120 cagaggtcag caggtcagga aggaggttaa aagttggcac caagctgcta ctgtgatcca 180 atcagctttc agaaggtaca gagaggagat caagttccag gccatgcgtc tgtctgccat 240 catcatccaa agacgctata gagctcttct tcaggggagg agagacagag agaactactt 300 gaggatgaaa cattgtgctg tggttcttca ggcagctttc agaggtcacc gtgtcagaac 360 tgaagttaca aacatgcact ctgcagctcg catcattcaa gccaatttca ggagattcag 420 aatgcagaaa gccttcagga gacaacgctg ggccgctgta gtccttcagg agagatttag 480 agctcaaaaa cagaaacaac atgcagtgaa acaataccat gaaatcagaa aagctgcagt 540 tttgcttcaa gctgctttca gaggaactaa atccagaaga atcctcaaac aaaaacatca 600 agctgccgca gttatccaga gatctttcag agcatactgt gaacacagga gctatc 656 <210> 7 <211> 652 <212> DNA <213> Oryzias javanicus <400> 7 tcgtcctcgt ccacgacttc atcgtctgca gccaagactc gctgttccag ctgcaatgtg 60 aagttcgagt ccgaggcgga gctgcagaac cacgttcaga cggtgcatcg ggagcaatcg 120 gcggacagca acagcgggca gctcaagact ccccaggtgt cccccatgcc ccgatccagt 180 ccctcgcaaa ccgaagagaa gaagacatac cagtgcatca aatgccagat ggttttctac 240 agtgaatgga catccaagtt catgtggcca accacatgct ggaggaagga ctgaaccatg 300 aatgcaagct atgtagtcag tcgtttgact ctccggcgaa acttcaatgc cacctgatcg 360 agcacagctt cgagggcatg ggtggaacgt tcaagtgtcc ggtttgcttc acagtgttcg 420 ttcaggccaa caaactccag cagcacatct tctccgccca cggccaggag gacaagatct 480 acgactgctc ccagtgtcca cagaagttct tctttcagac agagctacag aaccacacgt 540 tgactcagca cagcagctaa cgtggcagag agttcagcgc cgcggcagag cagaaggatc 600 acatgatgcc gagaacaatg accgaccgcc aattaccatc agggcagttt tc 652 <210> 8 <211> 1930 <212> DNA <213> Oryzias javanicus <400> 8 cggggaattt catggaggac gagcagtggc tgtccaccat ttcacagtac agccgcaaga 60 tcaagcactg gaatcgcttc agagacgagg tcgaggatga ttatgttcgg acctgggatg 120 aaaatcaaag ctccaacgac aacgtagaca ccaccaagga cccgtgtcaa aaggttaagt 180 gcagccgaca caaggtgtgt attgcccagg gctaccagag agctgtgtgc gtcaatcgta 240 agaagctgga acacagactg aagcagcccg ccctccgctc tcctgatgga aactgtcagc 300 cctgtcccat ctcctccacc gggcccgtgt gcggatcgga cggtcacaac tacgcttcga 360 agtgcaagct ggagcagcag gcgtgcctta cagggaagga tctcaccctg aaatgttcag 420 gtctgtgtcc ttgtccaact gcagctccta cgtccaagga aggcaagcgt gagggctgca 480 ccggacagga cctgtctgat ctcggcgagc gtcttaggga ttggttccag cttctgcaga 540 gcaatgctaa gcagaacaac agtaagcctg gagccagatc cagcaccaca tcagtgctgg 600 acaggagttt ggtggccagc tgtaaggact ccataggttg gatgttctcc aagctggaca 660 ccaataatga cctgtatttg gatcaggccg agctggccgc catcaacctg gacaagtacg 720 agatctgcat tcgtcccttt ttcaactcct gcgactcgta cagggatggc aaggtctcca 780 cggcggagtg gtgcctctgc ttctggcgag agaagccacc ctgcttggct gaactggaga 840 ggatccaagt cttggatggt ggaaagagaa agtttggtcg attcatcccc agctgcaatg 900 aagacggctt cttcaggagg cagcagtgtg acaggggcga gtgctggtgc gtggatcaga 960 acggaggaga aatagctgga tccaggattc ggggaaagcc aaactgtgat tatgaaatgg 1020 catattcagg agatttcggc agcggggtcg gatgggagga tgaggaggag aaagaggcag 1080 aggagactgc agaggaggct gaagaggagg agggagaagt gggagaggtg gatgacgggg 1140 gatatatttg gtaaatgccc aacgtgaaag ccaacctctc tacaggagca cttccatggt 1200 cctgaaaata cacacacaca cgcaccaaca aacacacaga cagatggaca cgatgaaccg 1260 ctcacactca gaacaacact tgctttggaa accgtgaggg agaggagtta aataagctgg 1320 gaggttgaag atgggagcat ttaatgttct taaaacgttc aagggaaggg gagatttatt 1380 gctattaacc cttcgtgggt ctggagttga gatttttgtc cttcgtacgt gtgactcctt 1440 gttcttcttt gttgtatgtc ttttgaacta tctttgagca gtttttagct gatgcataat 1500 ggaggcttta agaagctgca ggtgctcgtc atgtgcttgc gttgaaaaaa actgagctcg 1560 tctgggtgca tttgggggct tttctctgcg gtcggaaagc acgtcggaca ggaagccggg 1620 tcagaaaaca gacaaacacc ctttgacttt atgatttcca tgtcatgcgc tttggctcat 1680 atgtgacatt agtgctgtct ccctaatgac ttattaagaa caagtttctc acagatcact 1740 cttaagcttg tatataatgt gtgtatccga aggcagaatg tcctcttcta gtcaaatgcc 1800 ttgaaagaac agcagattga agctgcttag ctgacaagtg tgcatcatgt cataatgtgg 1860 attaattact gtgtttaata aaaaaaaaga attaaataaa ggtatctctg tggctcagct 1920 ggccaccatt 1930 <210> 9 <211> 583 <212> DNA <213> Oryzias javanicus <400> 9 aagcagtggt atcaacgcag agtgccatta cggccgggtc ggagatggcc atttccggga 60 aggcggtggg cctctacttc gaagagaagt tgcaggagat gttcccaggc cagaacttcc 120 cagaaacccc agaagccgag cccccggatg aaaaggagcg agaggaggaa acggaggact 180 ctgaggacga cttcatacag ccccgacgca aacggttgaa aacggacgag aaggtcgtcc 240 acatcaaata gtgactgaat gaggagtgaa gactgtcttc ccagactccc gtttcttcag 300 gaggaggaga acttctcaga aaacccggtt catcctatgg ttgcctttgg aagaactctg 360 atctgcaaca ttgtacagat gctgaagctg gactggattt gcagtagtga gcattgggtt 420 gttttttttc tatgcgtttg tagaatcatg tgatcatttc cttcaatccc gtatttgttt 480 gctgtatcat atgcttggag atggagccga ctgagtcttt gtatgacttt ggagatgttc 540 tgtaaataag agaggagccc tctgaagata ttctacacta tgg 583 <210> 10 <211> 580 <212> DNA <213> Oryzias javanicus <400> 10 atcgcgcggc tggaggagaa agtgaaggtc ctgaagaacg acaacgcggg gctctccaac 60 accgcgtcgg tgctgcggga tcaggtcgcc cagctcaggc agaaggtcct gacgcacgtg 120 agcagcggct gtcagctgat gctcaccagc aagatcgaag cgttttgagg aaacagagac 180 tactgaagga ctgaaaagtg ataacactgg agtcatggtc tgcatgcgca gcactggaac 240 cccggccgat gctgccggca tcacaggccc gagtcgagac aactcggccg cttagactga 300 ttgaattggt acttccggat gctggacacc gctcttagga ccattcaaag cagggcggca 360 tccagagacg gagcaagcgg gcactggccc cgcgcctcgg gtttactaat ggtagaaaat 420 gggaataatt attgtacctt tctgacccta ttgtcattca atgctgcatt tattcagtat 480 gtaaattatt tttgtttacc tggttgatcc aggcaaactg atgtccaatg tttacagtgt 540 ctttattttt atttgtgacg tgtatttaag taaagtgttt 580 <210> 11 <211> 572 <212> DNA <213> Oryzias javanicus <400> 11 ctctgagagc agaaggtcta ccatccacag acctgccgac ctgacaaacc ccacaaatgt 60 cagcttggca tctttgagtc ttggccatgg actttggcaa gtggaaaatc tctcccatga 120 ctcgctgatc aggagagctg cttcagtgat gaccgacagc tcaagtacct tcctctctca 180 ggcaaccctg gctctcagcg atgcactgac tgactactca aaagctgtcc actcacgcat 240 cgccttccaa aagcgatatt tgtcaacttt ggggaaactg agtccagcag aggagggatc 300 tctccagcag accattagca gctggcgcgc tgaggctgct gagaggctga gcgaatgcaa 360 acgctatgaa tcaacttgga acagtgctgt caacctgtgt aaaatggcag ccgatgctgc 420 atacagctct ggagcccagc aggcatccat ctccatcagg actaacatca aggtagccga 480 gtcgcagttg gaggaggcac ggaagctgtc ggcggaggca gagaagaaac tggccgagac 540 taaagtggag gagatcgaga ggatggccga gt 572 <210> 12 <211> 292 <212> DNA <213> Oryzias javanicus <400> 12 aacacaaagt catcgttgtg ggtttggaca acgccggaaa gacaaccatc ctttaccagt 60 ttctaacgaa agaagccgtc cacacgtcgc ccaccattgg cagcaacgtt gaggagatca 120 ttgttcggaa cacgcacttc atggtttggg acattggagg gcaggagagt ctgagagcca 180 gctggtactc ctactacagc aacacagaga tcatcctttt ggtggtggac agcactgacc 240 gtgaaaggct gcctataacc cgaggggagc tccaccaaat gcttgcacac ga 292 <210> 13 <211> 543 <212> DNA <213> Oryzias javanicus <400> 13 actttttgcc ttcttgttga tttttttggg agggttttca atcgctccac catgtgtaaa 60 ggactagcaa ctctccctgc gacctgcttg aaaagcgcca aagacatcaa gcacaaactg 120 agcttcttac tgcagaagcc cgaaccccaa acagccgatc agaaggaggc aaaggagaaa 180 accaccgctg caaagagggt tccggatcca tctgaggtgg aaaaatggaa ggaatcattc 240 agccatgtga tgagcagtga aatgggtcgt acagtgttta ccagcttctt gcggtccgag 300 ttcagtcaag aaaacgtgga cttctggatc gcctgcgagg acttcaagaa gattcagcct 360 tcccagatgg cggccagagc gaaacagatc tatcaacaat ttgtagaggc agatgcccca 420 aacgaggtaa acctagatgc agcagccaga gaaaaaacca ggcaggaagt ggagaatgtt 480 agcccgtctt gctttaacga ggcccagaag ttgatctaca ccttgatgga aaaggactct 540 tat 543 <210> 14 <211> 536 <212> DNA <213> Oryzias javanicus <400> 14 aagcagtggt atcaacgcag agtggcatta cggccggggg gtttactttt atggcatttc 60 gccgaaggaa caagagttac cctttcttca gccaggagtt cttaattcag aaccatgccg 120 atattgtgtt cagtttggtg attctcattt tgattggact gatgtttgag acgacagcaa 180 agacggccat attgttcatt cagcctcagt ataacgtcac gacattatca ccagagggag 240 aggtgacaac gtatctgtac ggatggaagg acttcgccac cgttctcttc tacttcttca 300 tcaccatcat cctccacgcc gtcgtgcagg agtaccttct cgacaaagtg aaccgacgcc 360 tgcacctctc caagagcaaa aacacaaagt ttaatgagtc gggtcagctt tgtgtgtttc 420 actttgtgtc gagcgtgtgg agcttctatg ttctcattac tgaaggatat cttttgcatc 480 ccagcagcct ttgggagaat taccctcatt cacatctcag gttccaggtg aagttt 536 <210> 15 <211> 535 <212> DNA <213> Oryzias javanicus <400> 15 aagcagtggt atcaacgcag agtggccatt acggccgggg gtatctcttc tgcctggctg 60 tgtgtgacag agtgggcctt gacgatgaag atctgtatcc tggggttgct ggtgctgggg 120 tgcgtgtgcg gtgcacccgt ggaagagggc ctgaagccgg agtcatgtga agacccacac 180 gcagtgaaag ctgctcatgt ggctctgagc aagatcaaca tggagcggaa ggagggttac 240 atcttcagcc tgcaccgcct gtccaacgtc caccacgcca agcacggaga gaatggtgtg 300 gtttattaca tgactctgga tgttgtggag acaaactgca gcgttcttag caggaaggat 360 tggaaagagt gtgaggctcg tccaaccagc gaccaacagg tttacggaca gtgcaaagca 420 gccatcttca tcaacaaggt ccacagagtg gatcgtctct acaaatacga ctgtgccatc 480 aaaccagttc cttctgccag actgtcagca atttgtcctg actgcccatc cttga 535 <210> 16 <211> 502 <212> DNA <213> Oryzias javanicus <400> 16 aggttactgt tcagtatcgc caggaccgtg gcgccatgct ccctgtgcgg gtacacacaa 60 ttgtcatctc tgttcagcat gatgaggata tctgcctgga ggagatgagg gatgctttga 120 aggagaaggt cataaaggcc gtcgtcccct gcgtctattt agatgacgac accatctacc 180 acctgcagcc cagtgggcgc ttcgtgatcg gaggccctca gggcgatgct gggctcactg 240 gtcgcaagat catcgtagac acgtatggag gctggggagc ccatgggggc ggcgctttct 300 ctgggaaaga ttacacaaag gtggaccggt ccgctgcgta tgctgcacga tgggtcgcca 360 agtctctggt gaaagctggt ctctgcagga gggttttggt tcaggtgtcc tatgccattg 420 gagttgccca cccctctcca tttctatctt ccactacggg acctctaaga agagtgagat 480 ggagctgctt gacattgtga gg 502 <210> 17 <211> 491 <212> DNA <213> Oryzias javanicus <400> 17 ccgcagtggg acattttgat tgacggatgt ccatatgaag atgatcgcta cctgtcggca 60 ttggttccaa ttgatgcctc ttctggattg ccgttcccaa ctcatcacag acgcttccta 120 ttcaagatgt ttacctttgt tgatcctcat tcaatggaac cactaaggga aaaggtgtac 180 attcactgta gcacagctgc atgcgttcca ggacagggta ccagttgtga accctcatgc 240 agcagaagaa aaggaagaga tactgacgct gtatccatta gaacggatga aagaaaggtt 300 gtggtatcgt ctggagaagt gctcatggtc gccgaagctg cacagcctga actgtgaaac 360 gacagaagct ccagagttct gaaaaaataa cattatgaaa atctgtttca tcatgggtca 420 aaattaaatg cataaaataa naaaaaaaaa aaaaaggccg cctcggccac tctgcgttga 480 taccactgct t 491 <210> 18 <211> 487 <212> DNA <213> Oryzias javanicus <400> 18 aagcagtggt atcaacgcag agtcctcaga ggacgtctac aagcgcttca gctgctcccc 60 gctgggcctc acttcggcgt acaccctgct gagctcggac ggacacacgg agccgcccta 120 caccacctgg aagatccgcc cctctgggga gagccgcagc acgctggact acatctggta 180 cacacccgcc gctttgagcg tggagagcct gctggacatc cccagtgagg agcagatcgg 240 tccggaccgc ctaccctcct accactaccc ctctgaccat ctgtccctga tgtgtgacct 300 cagcttcagg gaggagcctc acaggctgct gtagcctatc agagcaggga agccaacttt 360 ttagtctgga caaagaactc tcacttcgga ccttaagctt ctatgaacat gaacttgtag 420 gacgacccca tgtctagact gctgctgggt ctggttctga cagcacagtc tgcccacggt 480 tccagtg 487 <210> 19 <211> 482 <212> DNA <213> Oryzias javanicus <400> 19 aagcagtggt atcaacgcag agtggccatt acggccgggg tcccagcagg aatccgggaa 60 gatggctcac gaagctccgt tccagctgct ccacagcgag ctcatccact acatctgcaa 120 gtcagccgac agcacagact cggaaaatgg aagaagtgtc accaaactgg aaaatctggg 180 tttcagagtc ggccaagggc tgatagagag gttaacgaag gacacggcgc gcttcaaaga 240 cgagctggac gtcatgaagt tcatctgcaa agacttctgg acctgcgtct tcaagaagca 300 gatagacaac ctgcgaacta accaccaggg catttatgtt ctccaggaca acaagttcct 360 gctgctgtgt cacctgtccg ctgggaaaca atacctggaa cacgctccaa agtacctggc 420 cttcacctgc ggcctggtca gaggagctct gtccaacatg ggggtgaaga gcatcgtgac 480 ag 482 <210> 20 <211> 1834 <212> DNA <213> Oryzias javanicus <400> 20 aagcagtggt atcaacgcag agtggccatt acggccgggg gactttcacg gaacacctca 60 atgtgtcatc atgcattcta ggtgttagct tgttttaagc ttttgccgta gaagatttaa 120 ctgtttatct ttcttttaat caacattcct gtcggatccg atcagatatt tatcttccag 180 gagtcatatt taaatgaatt taatttaact gcagaacagc gggaactttg aaggctagtt 240 gctaacagtt agccaattgc taacaacact gagtggagca gacttccatg cgtccgctac 300 tcctttcccc tccacgcagg cgatcaaaac tactaaacaa gacctagaca gacatcatgg 360 agctccaagc ggtgttgatg gcggctggcg gtggttcccg gatgactgat ttaacttaca 420 acacccctaa agccatgctg cccgtcggca acaagcccct tatctggtat cccttgaact 480 tgttggaaag ggtgggattt gaagaggtca ttgtgatcac cacaaaagaa gtccagaaga 540 tgatgagcac ggaccctaaa gtgaaggtgg acgtgaagat gaagctggat gtggtttgta 600 tccaggagga tgcagacatg ggcaccgctg acgctctcag acacattcag cagaagatta 660 agacggacat ccttgttgtg agctgcgacc tgataacaga tgtggcgctc catgaggtgg 720 tcgacctttt cagggcccac aatgcaacgc tagccatgct aatgagcaaa gcccatgaat 780 tcacagagac tgtcccgggg cagaagggca agaaaaagac cgccgagcag agagactttg 840 tgggtgtgga tcagtcggga cagcggctgc tcttcatggc caatgaagca gacctggagg 900 acggcctctc cattaggaag tctgtcatta gaaaacatcc cagaatgcac atcaaaacag 960 gcctggtgga tgctcacctc tattgtctga aaaaggctgt ggttgacttt ctttctgaaa 1020 acaagtccat ttcatcgatc cgtggcgagt tggtgccata tttggtgcgt aagcagtttt 1080 ccaaaacgac aaacagtgag aaaataaaag acgactgtga agatcaaacc cagaaaaaga 1140 gcgacagctc tacagaacat gaacttttca tctcctcacg ggatgaaccc ctcctccagc 1200 gagcccagga actctcctgt tggaatgacc atcgtgggga catgagtgaa gcttaccacg 1260 gaggaaagct gcgctgttac gtccacatta tggagcaggg actgtgctgc cgtgttaaca 1320 cgctggctgc ttatatagaa gccaaccgcc tggccccaaa gctgtttgaa gagccagcag 1380 tccacccatc gacagtcatt tctgagagat gtcagatggg atcagacagt atcatcggag 1440 ctctctgtca ggtggcagat aaaacgtcca taaaaagatc cacgattgga aactccacta 1500 cagttaaaga aaaggtcaaa gttgccaact ccattatcat gcatggggtt accattgagg 1560 agggatgcag catccagggc agcgtgatct gcagtaatgc agtaattggc agaggagcag 1620 acctcaaata ttgcctggtt ggaaatggac agcggattga accagaagcc gaacggacca 1680 acgaggtcat cgttggaacg gaccagctga tggagatcta gcttttatag ggacagaaat 1740 gtcctccttc actgacccaa aggaaacaaa ttctccagag gactgaagga tcagaagcca 1800 ggactgtctg acagtgctgc tctcttactt tttt 1834 <210> 21 <211> 485 <212> DNA <213> Oryzias javanicus <400> 21 aagcagtggt atcaacgcag agtggccatt acggccgggg tcagcgcgca gttgcttgat 60 atcgctggga ggaaaatgtc ttgtgggctg aggaaagaga ccctagctgt ggccctggat 120 tacctgtccc tgagctgcag gagcccactc ctccaggccc ccccacctcc cagcgagtca 180 gcttctgcca tgaggcgcct ggcccaggac atggaggcgc agtaccagcc ccgcttctcc 240 gcgctagctc aggacttcag gaagcacagc gggccggacc tgtgctccag cctcaggaag 300 gtgatggagg agctggtggg agatgaacac ttgaactggg ggagggttgt ttcccttttt 360 gcattcgtgg gagtgctggc gagacagctg agggggcaaa cggacacgaa cccggggctg 420 gacctcgggc gggaagtggc gcccggacct gtgagctgcc aggcgctggc agaaactgta 480 gctga 485 <210> 22 <211> 444 <212> DNA <213> Oryzias javanicus <400> 22 acgacagaag cagagaagaa gccggcagga gaccgaaact gcgagtcaaa aaaagttgtt 60 ttaaccttta aaaaacgtcg cgttaaagat taaaaaaaga aagcatgact ggagcagaca 120 ttgagaaggg caagaaggca tttgtccaga agtgtgctca atgtcacacc gttgaacaag 180 gtggaaagca caaggtggga cccaaccttt ggggcctctt tgggcgtcag actggccagg 240 ctgctggctt ctcctataca gatgccaaca aaagcaaggg cattatctgg aacgaggaaa 300 ccctgatgat ttatctggag aacccgaaga aatacattcc agggacaaag atgatcttcg 360 ctggcatcaa aaagaagaat gagcgaactg accttatcgc atacctcaaa tctgcaactt 420 catagggaac tctccagctc acta 444 <210> 23 <211> 1791 <212> DNA <213> Oryzias javanicus <400> 23 agcagtggta tcaacgcaga gtggccatta cggccggggc aataggccct ttcatgcgct 60 ttatgtctgc atcagactgt caaaggcgtc gagaggccca tcaggaaaaa gctttctgtt 120 ttcctagtca aatttgaaag agctgtggag catcgctgcg cagctggcac cgcgcgcgct 180 aaaggatcgt gatcgagatg ctgctgctgc tgaggctgtg tggacatgag tggtattaat 240 aggagggctt gagtgtcaaa ggctttcaca gccgagacaa atctagaccg gggggctcgg 300 tggagagtcg gtggacaccg gtttgggggg cttcctttcc agactgcgca gttggaatac 360 agaggaaaaa ccacagggat ccgctgctca tcagactggc acgatggaaa acgtactggc 420 agttcttaat ttgggcgatt ttgcccaagc tttctccaaa atgggaatgt ttcccgtctt 480 tgatcttgcg tattacatag tgtccatcct ctacctcaaa tatgagccag gctcagttga 540 ggtttctcgc cggagtcctg tggcctcctg gctctgcgcc atgctgtact gctttggtag 600 ctacatcctg gcagacatca tgcttggaag cagccccctc gactatttcc aacacaacag 660 ccacatcctg ctggcctcag ctgtctggta cctcattttt tattgcccgt tgaacctttt 720 ctataaatgt gtggctttcc ttcccgtcaa actggtgttg gttgccctga aggaggttgt 780 tcgcactcgc aaaatcgcag caggtgttca ccacgcccac cacgcctatc atcacggctt 840 cttcatcatg gtgatcgttg gatacgttaa aggatctggg gtggctctta tttccaattt 900 tgagcagctg ctgcgtggtg tttggaggcc cgagaccaat gagatcctca acatgtcatt 960 ccccactaaa gccagcttgt atggagccat cctcttcacc ctgcaggagg ctcactggct 1020 gccagtgtca aagggcaccc tcatcctcgt cttcaccctt ttcatggcca caagcaaggt 1080 tgtgatgaca gcccggcatt ctcacggctc ccccttcgcc ctcattgagt cctgggtttg 1140 ccatctgctg ttcggctctc ctctggctgg aggtgaggag gaccaccatc acgcctcctc 1200 tcctgccaca ccgtcttcac ctctcaaaac caaggaggag ctgagcgaag gcgctcggaa 1260 gaggaaagcc aagaaagcag agtaggacgg caaaactgca tcggactcgc cctcatgctg 1320 ttcacaggat gagacccatt cttttctgac gaaagggcgc ctttgatcct ctgtcaaaaa 1380 aaaacccttt ctattggagc aacgtggtgc tttctgcatt ttaaatagct gaaggactct 1440 gaggcaaacg ttttgtattc tcaacccgac ctggacactt ggtgaacacg tgctgtgtgg 1500 tcattcaagt tcaggaacca cgtggagggc ctctgtttca catcagtata tgtgttacca 1560 gttaaagctg tttttcttgt actccaatta aaacataatt tgagttcaga aagaagtgaa 1620 atatgtaagt aaaacaaaaa ttcaaatgta aaatgaagca ttatgaacaa aacaatgctg 1680 gctttctaca ctgagaagaa aagtcatatc tttaaataaa aaataacaga aaaataaaaa 1740 aaaaaaaaaa aaaaaggccg cctcggccac tctgcgttga taccactgct t 1791 <210> 24 <211> 428 <212> DNA <213> Oryzias javanicus <400> 24 aaggaactgt gagcattggc tgtagccgtc ttccatctcc tcacatttat cagctgctgt 60 ctgcatatca ctataggtca tggcaaaaac tgctgcaccc gactccacca ggaatttaca 120 cacttgaaca ttgttgcagg atgcagcgca gtgaagaggt gtccatccat cactgtcagc 180 agcattaaca ttaactccaa actgaaccaa gaacttgacg atctccgtgt gtccagcaca 240 gacggcgtta tgcagagcag ttatcccttc atcgtttggc tgactcggat cctccacttc 300 atatatgatc ctctgcacca ggtcgtactc tccctccaga gaagagtcca gcagcagagc 360 cagcgggttg aacttcaccc tcatgttgtg atcgatgcgc tcggaaccaa gcttgcgcaa 420 attggttc 428 <210> 25 <211> 423 <212> DNA <213> Oryzias javanicus <400> 25 gaaaggcgtg ccaggaagag ttcgtcaaga gagctttggc taacagccaa gcctgcgtgg 60 gcaaatatgt ttcctctgga gccagcgctg ctggtggaga gtcattgtac gtagctaacc 120 atgcttacta agcactgacg ccccactttc gacccaccgc ctctgcaaca gaacagcaca 180 cgtcctcaaa gacaatgctt ttaaagtact gtctctccac tatcactgca actttagtaa 240 ctttagtaac caagaaatat gaaaccaaat gatgagaaaa atctttcttc tagcagttgc 300 taaacaagtt ctgacttcat tcccttacct tttattttta agcgcctttt tttacaggtg 360 aaaatttcca ctgtttttac acagctcttt ctactttcct tggtctgttt ccaccttaat 420 gcc 423 <210> 26 <211> 403 <212> DNA <213> Oryzias javanicus <400> 26 ctccctatgg aggagcagct gcgacgtctc caggaggagc gcacatgcaa ggtctgcatg 60 gacaaagaag tcaacatctt tcatcccatg tggacacctg gtggtgtgca aagagtgcgc 120 cccatcgctg cgaaagtgcc cgatctgccg aggcctggtc aaaggcacgg tccgaacctt 180 cctgtcttag cctggtgctc tgtcataact tcgtcaaaac agaggccttt tttttcttct 240 ttcactcgtg ataaattcag ttagaccgat gttagttttt tgtttttttt tcaacggttt 300 actaatgata ccagagaaac atggaaaggc atttgcagag ccatgtgtga agctagcacc 360 aatttttttt tagtaaacat attgtaaaat agtttgcacg ttg 403 <210> 27 <211> 1769 <212> DNA <213> Oryzias javanicus <400> 27 tccagctcct gcaggaggtc caggacttag gggttagaat cccaagacct ctcggaaacg 60 gaccaagcag attcatccct gaaaaagaga ttcttcaagt cagtaaagtg gactccagga 120 cgcagtcgat atttgaggat gcgtttgcag ccctcggtcg cctggagaac atctccctcg 180 tgatgggctt ccacccccag tacctggaga gcttcctccg gacgcagcac tacctgctgc 240 agatggacgg acctctgcct ttgcactaca gacactatat cggcatcatg gcggcggcga 300 gacatcagtg ttcctatttg gtcaacctac acgtaaacga cttcctccag gttggcgggg 360 acgccaagtg gttgaacggt ctgggggaag ccccgcaaaa gctgcagcag ctcggagaac 420 tcaacaaaat cctggcccac cgtccctggc tcatcaccaa ggagcacatg gaggctcttc 480 tgaaggcgga ggagcacagc tggtcgctgg cggagctgat ccacgccgtg gttctgctca 540 cgcactacca ctccctcgcc tccttcacct tcggctgcgg catcacgccg gagatccact 600 gcgacggcgg ccacaccttc aggccgccgt cgctgagcca gtactgcgtg tgcgacatcg 660 ccaacgggaa cggccacgcc aatcagcacg acgatcagct gtgcgaccag gacatgtgtg 720 gggaggtgga ggtgctgatg gagaggatga agcagctgca ggagtgccgc gacgacgagg 780 aggcgagcca ggaggagatg gcgacccgct tcgagaggga gaagactgag agcatgctgg 840 tggtcacgtc cgaggacgag gagtgcgttc cgtccaggga catctcccgc cactttgagg 900 accccagcta cggctacaag gacttctcca ggcgggggga gcacgtgccc acgttcagag 960 cgcaggacta cagctgggag gaccacggat actcactcgt caacaggctg tatccggacg 1020 tcgggcagat gctggacgag aagtttcaga tggcctacaa tctgacgtac aacaccatgg 1080 cgacgcacaa ggacgtggac accagcatgc tgcgcagagc catctggaac tacatccact 1140 gcatgttcgg catcaggtat gacgactacg attacgggga gataaaccag cttctggacc 1200 gcagctttaa gatctatatc aaaaccatgg tgtgcagccc tgagaagacc accaaacgaa 1260 tgtatgagag tttttggagg cagtttcagc actccgagaa ggtccacgtt aatctgcttc 1320 ttatggaagc gcggatgcaa gccgaactgt tatacgctct gagagcgatc acacgctaca 1380 tgacatgaag tgcttttgct gttctttttt attgtccttt tactgtcgtt gttgtatact 1440 gggacacaaa gaaaaaaaaa atgacgggag gggtgggagt tcaacaaaaa tgttggctgg 1500 acattgagga ggatcagaac aaaatggaaa aaaaaacaaa acagatttct gctgtggaaa 1560 cgtcatctca agactacaag tggacgcaca ctcagcggtt ctgcccgcag tgccaaaact 1620 gaccaagagg tggcagcctg gagcgagcgc ctgtcctgct gaaggggttt aaatcctgac 1680 catccaccgg acaccccagg actgcatttc agtattccgg cacgccgcgt gctggtttcc 1740 aatttcactc gtcaaacccc tgagaacaa 1769 <210> 28 <211> 1755 <212> DNA <213> Oryzias javanicus <400> 28 ggacagagtg agcttgttcg aagacacatt cagaaagagt tttggcgagt ccaggatgtc 60 cttgagggac tacacaaaaa ccattcatcc agaggcactg acacagccaa gcacagagtg 120 gccagcggtg cgtctggtcc tttagcacca atagtccagc cagtcccctg agctcagtaa 180 gcctaaccag tccactcagc cccttctccc cagtgcaagg ttgccaggcc tcccccacca 240 aacaactggg cccggagggc agggcaggtg aacagagcag tccgagagat gttcaggacc 300 aggttcagga caaacaatcc acaaacaaag ttggtatcgt tcctccgaga accaagtctc 360 caactgaaga agcccacaga aatgcagctg aagcgccgcg gcacatctcc aaggaccgcc 420 caaagagtgc agtgtttcct gcagagctga ggtccaagat gagcctagag gagcaaaatg 480 agcgaattcg tcgtaaccag agcagctcca tgagagacaa gaggcgaagc cttaatctgt 540 cggctggccc gcttccacct aacttcaaag tggtccgaag gcgagtaaca gctcatgaaa 600 ttgacattaa ggacctggag gcagcagttc gcgatgacaa ccaagagtct ccatgggagg 660 agattgctcg gctcaggcgg ttgcagaatg acggggtgta tgacagcaga gagatgacag 720 ctcaagacca acccatgatc cctgagggcc tcctggatcc agagaacgac actcctctga 780 gtccagagga gcagaaagag aagcagaaga agctggatcg gatcaagact ctaatagcca 840 aatcaaacct gcagaacgtg gttccggttc tggatggtcc agtggagggt ggagcttcag 900 ccagctcaca gcaccagcta ctggaacagg agaagcggat tgagattacg tgtgctctgg 960 ctgcggaggc ttctcgtcgt agtcgtcttc tgtccgccca gtgtgcctcc agccccccca 1020 cgtcaccgag cagcctggtt cctccccatc ctccagtgac ttctttaacc ctgcacacat 1080 cctgaaagtg taagacgcac agctttggca gcagttaagt tcgatggagc atctttctga 1140 ggattcacag gagcaacatc aaaggaggga gcatccaaag tcattggagg caaggcaagg 1200 gaatgcgccc ccaccccctg aggatctaac ccatgtagca caaaggcttc agacctcttc 1260 tcgccaactt gtgtcatcat ctttaattta gctcaggaca aattcttctg aacctgctga 1320 cactgaaatc ttttacaata acatcgtcaa actgtgagct tactgtcagc tgcttttgac 1380 atgctctgaa acgttgggag gtgcgactcc taaggcttac tgtggagggg gagccccaac 1440 tgtttacttc tgtgtttatg tcggagagga aacttaagct tcaacgtccg cgtgcctgaa 1500 agtgtggaga aagaaacctc cacaaaaaaa agcaaaacaa aaaaaccctg ctgaacaatg 1560 taacacggtg gggcagatca ctgcctctga tattgtcttt gaaacagcac gccccaaatt 1620 aagaaaatca cactggagtg agcaggagcc ttcctgacat ctgtggattt cactgaagct 1680 ctgcagaact ggactggagg gtctcagatc ctctgcaggg ctggtccagc agctgactca 1740 gatcgtgcag tttct 1755 <210> 29 <211> 368 <212> DNA <213> Oryzias javanicus <400> 29 gatgaaccaa aactcaacat cctcatcaac aacgctggcg tgatggtttg tccgtacggg 60 aaaacggccg acggcttcga gatgcagatc ggtgtcaatc atctgggtca cttcctgttg 120 acctacttat tgatagacct gctgaaacgg tcggcgccgg cccgcatcgt caccgtgtcg 180 tccatggctc acgcctgggg ctccatcaac ctggaggacc tgaacagcga gaagagctac 240 agcaagagca aagcctacgc ccagagcaag ctggccaacg tcctcttcac gcgctcgctg 300 gccaaacgcc tggaaggtac cggcgtgacg gcgtactccc tccaccccgg cgtggtccag 360 accgactt 368 <210> 30 <211> 351 <212> DNA <213> Oryzias javanicus <400> 30 aagcagtggt atcaacgcag agtggcacca atcagcgtca gggtccagag tgagatcggt 60 cagagagccc agcaagtgaa ggaaatggca agcccctacg ttgaacagat gagggaaagg 120 ctggacccct acgcccagga cctccaggct cgtctcacca gcctctatga ctccttcgtc 180 aagtccaact aaatccatct ccagcttacc ctacatacaa agaaactgca cctaccatca 240 aacagctgtc tgacatttca gacaaatgtc ataaatagca aatatgtatt ggtctgtgac 300 ctcactctgt tctctgtcta aaatatgaaa ataaactaaa agcaaacacc g 351 <210> 31 <211> 353 <212> DNA <213> Oryzias javanicus <400> 31 aaggcattca gcattgcagt tgcagtgaca ctcgtgctcg cctttatttg catccaggag 60 agctctgcca tcccagtcaa tgggcaggtc acagagctgg aagaagcagc aagcaatgac 120 actccagttg cggcacgtca cgagatgtca atgcaatcgt ggatgatgcc aaaccacatc 180 agggaaaagc ggcagagcca cctctccatg tgcagcgtgt gctgcaactg ctgcaagaac 240 tacaagggct gcggtttctg ctgcaggttc tgaggggtcc tgcgacaacc accacacatt 300 aatttattat taggcttgtt tttccatact ttccacaaga aattcacttt ttt 353 <210> 32 <211> 1735 <212> DNA <213> Oryzias javanicus <400> 32 aagcagtggt atcaacgcag agtggccatt acggccgggg agagcaactt cgagtagcaa 60 agtagcaact tcaactccct ctcaaggaac tttctcaaag gcagaaaaaa ggaattttac 120 ccacttccga gtggagtttt actggaatct ttcttcttgt tttttcgggg aaatatgatg 180 ttcaccgcct tcaacacaga gtgcgactct tcctcccgct gcagcaccgc ttctccgtcc 240 ggagacaacc tgggatacta cccgtcacct gcgggatctt actccagcat gggatctcct 300 cagtctcagg atttcactga cctgacagca tcaagtgcct ccttcatccc caccgtcaca 360 gccatttcaa caagtccaga cctgcagtgg atggtccagc ctgtggtctc ctcagtggct 420 ccctcccaca gagtccaccc ctacagctcc agccccgctt accccagatc atccatgagc 480 tctccgtcca agatttgctc ttccagacgt ggcaaagtag aaaagataag ccctgaggag 540 gaggagaaga gaagaatccg cagagagaga aataagcagg cagcagctaa atgccgcaac 600 aggaggcgag agctcacaga cacccttcaa gctgaaactg accagcttga agatgagaag 660 tccagcctgc agaacgatat tgctaatctg ctgaaggaga aagaacggct ggagttcatc 720 ctggctgccc accagcccat ctgcaaaatc ccatcagagc tggagagcga gttccccctg 780 acctccatct cctccaccct tccatgcctc tccaccacag tgtcttccac gaccaccttc 840 acctccagcc agcaaaccat acctccaact tccaactcta tcttctccag ctccatcctc 900 tccaccacca cctcaacaac caccaccact gcctctgaca gcacagtcaa gatgagcgac 960 ctcgaggctt ccattctgga ggagtctttg gacctgctgg aaaaaacgga catgaagaca 1020 gcgcagtctg tgccagaggt tgacctttcc agctctcttt acagtaatca agaatgggag 1080 cctcttcatg cctcttcagc caacgtcgac tttgagcccc tgtgcacacc agtggtgact 1140 tgcactccgg cctgcacaac caacacgttc tctctggtgt tcaacttccc agaagctgag 1200 accttcccca cctgtggcgt tgcacacagg agagggagca acagcaatga ccattcctca 1260 gactcgctaa actcacccac cctgctcgct ctttaaggac attttctatt aaaaaaaaaa 1320 tccttcctat caagtcttga aaaattagca gaggcatgag ctttggaaca gatggcaaat 1380 cctatgttac ttgcctttat ctctacttgc ctattaacac caatgtagca agttattgag 1440 catgatttaa acaaaaaaaa cacattgttg ttactattat atttatggtg ctatagatga 1500 caatacttgt tgtgttttca gagcaatagt tatatttttg gtttgttttc tggttatttg 1560 aatgtcaaag taaatttttt tctcccatta aactgctgtg gtgccatggt ctgcaagtcc 1620 atcagactgt gaagttttct gtgaaaacat tagtgcttgt aatttattaa atttctattt 1680 atttattttt tacagacgaa tgttgtgtaa ataaaacata tatatgaaat gaacg 1735 <210> 33 <211> 344 <212> DNA <213> Oryzias javanicus <400> 33 tctggttttt ggggaacggt atgagtattc tgataaacag taccagcaaa ttctgaagga 60 cattaatgac gtcatgatcc tgcagggagg tttttcagct cagctcttca actcgtttcc 120 ttggctgatg aagaagcttc ctggacctca tcaggaaata ttatctctgc tgtcaaagtt 180 aattgactat gcaaaagtta agattgcaga gcacaaagaa aatcttgacc cctcctttcc 240 aaaagactac atcgactcct ttctcataga gatggaacag aacgaaggcc aagattctag 300 ctttgatata agcaatttgt gcatgtgcac cctggacctt ttta 344 <210> 34 <211> 338 <212> DNA <213> Oryzias javanicus <400> 34 ttcatcatgt ccacctcaac tttggtgttc tcgtctacgc ggaattcccc cttggttgtc 60 aaattagcat caaatggttt ctcccactgt cctcggaagt acacatagtt gatgagcacc 120 atagctgttt cagggtccag atccttcacc atgtctttaa ttttatcatt ggttttactg 180 gcaatgtgct tgttaatctc agctgtggct tcctgtggct tactgaagtc aacatttaag 240 acctcaccgg agtagtgctt cttgatacct gcaatgaatg actccaaagg actaaaacca 300 gtgcgcacag ctgcagtgtt gccaacatcc aactgctg 338 <210> 35 <211> 325 <212> DNA <213> Oryzias javanicus <400> 35 agcagtggta tcaacgcaga gtggccatta cggtcggggt ttagttttag tttttgtttt 60 tgtttttctt tacggctgcc tgaggacaca cagggagaga ccggatgagc atggcggagc 120 agaagaagat cctgtgcgtg ggtctggtgt gtcttgacat catcaacgtg gttgacaaat 180 accctgagga agactctgac agcaggtgtt tgtcacagcg atggcagcga ggcggcaacg 240 cctccaactc ctgcaccgtg ctgtcgctgc tcggagctcc gtgcgccttc atgggatctc 300 tggctgctgg tctgacggct gattt 325 <210> 36 <211> 320 <212> DNA <213> Oryzias javanicus <400> 36 gcagtggtat caacgcagag tggccattac ggccgggaaa attcaaggac atccagtggg 60 atgagtggat catcgcgcct gagggctacc acatgaacta ctgcatgggt cagtgccctc 120 agcatctatc tggctctacc gggtattgcg tcctctttcc acgccaccat cttcagtcca 180 gctaaaaagt caacggcatc aacacagcga cagcttcatg ctgcattccc actgaacgtc 240 ctagtccgct gtccatggtc tatttcaact ctcagaacaa acaagcatcg taaagacaga 300 cgtcccggac atcgatcgta 320 <210> 37 <211> 317 <212> DNA <213> Oryzias javanicus <400> 37 aagcagtggt atcaacgcag agtggccatt acggccgggg actcacaccc ggagtcgcaa 60 gacagaccga agcgtctcac aaacgaggac taaagatcaa cccaggcaaa aatggtgaaa 120 gttggtatca atggttttgg ccgtattggc cgtctggtaa ccagggctgc cttcacctcc 180 aagaaggtgg agattgtggc catcaatgac ccgttcattg acctggacta tatggtctac 240 atgttcaagt atgactccac ccacagccgc ttcaagggcg aggtcaaagc tgagggaggc 300 aaactcgtca tcgacgg 317 <210> 38 <211> 1712 <212> DNA <213> Oryzias javanicus <400> 38 aagcagtggt atcaacgcag agtggccatt acggccgggg aggcagcagc gcgtgctgag 60 cgaaaaacgt gtccgctcaa agcggcgagc acgccaaata agaaaaataa tcttaaaaac 120 cagacagtaa ctttttctta aaatgttggt tttatttgaa accgctgcgg gatacgctat 180 ctttaaggtt ctcgatgaat ccaaactgca gcaagtcgac agtctttata aggagtttga 240 aactcctgag aaagctaata aagtagttaa actgaagcat tttgagaagt tcaatgacac 300 aaccgaggct ttagcagctg caactgccct ggtggagggg aaaatcggta agagcttgaa 360 gaaggtttta aagaaagttg ttgccaagga agctcatgag gaacttgccg tcagcgatgc 420 caaacttggt ggagttatta aagacaagct ggagctgagc tgcatccaca gctctgctgt 480 ggctgagctg atgagatgca tcaggagcca gatggagagc ctcatctctg gacttccccc 540 taaagagatg agcgccatgt ctctgggttt ggcgcacagc ttatcccgct acaaactcaa 600 gttcagccct gacaaagtgg ataccatgat tgtgcaggcc atctctctac tggacgacct 660 ggacaaggag ctgaataact acatcatgcg ctgcagggag tggtacggct ggcacttccc 720 cgagctcgga aaagtcgtcg tagataactt ggcttattgc aaaaccgtcc ttaaaattgg 780 ggaccgcaca aacgtggcga ctacggatct gtccgagatc ctgcccgagg aggtggaggc 840 agaggtcaag ctggctgctg aaatctccat gggaacggaa gtgtccgagc aagacatcgc 900 caacattcga catctttgcg accaggtgat cgagatctca gattaccgcg cgcagctcta 960 cgactacctg aagaaccgga tgatggccat cgcccccaac ttgacggtga tggtgggcga 1020 gctggtcggc gcccggctca tctcgcacgc cggttcactt ctgaatctgg ccaagcatcc 1080 ggcctccacg gtgcagatcc tgggcgcaga gaaagctctg ttcagagctc tgaagacccg 1140 caaagatacc cccaaatatg gtctcattta ccacgcctcc ttagtgggac agaccacagc 1200 caagaacaag ggcaagatct ccagaatgct tgccgcaaag gcagcgctgg ctattcgcta 1260 cgacgctctg ggagaagaca caaatgcgga gatgggagct gagaaccgag ccaagctgga 1320 ggccagactg cggcagctgg aggacagagg catccgcaaa atcagcggat caggcaaagc 1380 cgtggcaagg gctgacaaat accaacacaa gagtgaggtg aaaatttacg atccatctgg 1440 agactccacc atcccctcca cctccaagaa gaggaaattc gaggaggtgg agcagcagga 1500 gaccgccgaa gagcccgcca caccggcgat gaagcccaag aagtcgaaaa aagagccgga 1560 agtagaagag gaaacgcctg aaacgccggc cgagtcggag gcgcccaaga aaaagaaaag 1620 aaaaggacaa gaaagcagca gcggaagagg aggagccagc tgaggaggtg aaggaggagg 1680 aagaggaggt ggtagtaatg gagacgtcgg ag 1712 <210> 39 <211> 294 <212> DNA <213> Oryzias javanicus <400> 39 aagcagtggt atcaacgcag aggaggttca cttcaaactc tcgacggctg ctgggaaaag 60 aggccatgaa gcagagacac ctgcggctcc tgggatacga agtcgttcag attccttact 120 acgaatatga aaagctgcac aacaagacca gtgtggtgga gtatcttcat caaaaaatct 180 tcccccacac atacaggatg agctggtgat aacatccact agaaatattt atttttgcca 240 aaatttaaca tttctcaact tcagcctatt tattatgcaa ataaaagctt ttta 294 <210> 40 <211> 556 <212> DNA <213> Oryzias javanicus <400> 40 ggatctacag aatgcagcgg tgctcattct agcaaataaa caagacataa agggctccat 60 gacagtagca gagatctccc agtgcctcac actcaactct atcacttcac acccctggca 120 tgtccaggcc tgctgcgccc taacaggaga aggtctacct gcctgcctag attggatgaa 180 atcacaggtt gtggtaaact gatgccactt ccagtgcctg aaacttcctt gaaccgcgcc 240 aaccttcgca cttttttgtg tgtttcaaag tgtttactgt gtgtggcatc tgtaacagag 300 actatagtct ccacgccttc tgcgtgtttg tgtgggagta ttcgaaacgg atggatgaac 360 attacagtga cctggacgtt ttatgttatt ttagtttgtt tatgcagttc tctttcttgt 420 aactgtggaa acacgcacta ctaggaactg tttttgttcc gtactgtgtg aagaggtgct 480 ttcagactgg atgccctacc tgacaagtca cattccactt tgcgtcattt tgcacgggtt 540 tggtacaaaa caaagg 556 <210> 41 <211> 287 <212> DNA <213> Oryzias javanicus <400> 41 aagcagtggt atcaacgcag agtggccatt acggccgggg agaaacaaac cggagagttg 60 agtttatttt cgagggactt ctaagttttt ggatttcttt ttactctata ttttatttgg 120 tttttcttca ttcgttgagg aaaagtcgag aaagaagcag aagaagaaac gatgaagtac 180 attataggaa tcggaggtgt cacaaatggt ggtaaaacca ctctgacaaa taaactgatc 240 aagactttgc ccaactgctg tgtggtgcac caggatgact tcttcaa 287 <210> 42 <211> 283 <212> DNA <213> Oryzias javanicus <400> 42 aagcagtggt atcaacgcag agtgggtgtg tgagttcaag gctcatgaaa ccagagtaaa 60 agcagttgat agtttctcta tggaggatta ttgtgttttg gtgacggctt caaacgatgg 120 cttcatcaaa atgtggaaaa tccatctgaa agagacgctg gagtctccga ctcttctggg 180 ggaagtgaac acatcagcca gactgacctg ccttgctgtg tggatcccat cctcagtaca 240 gcaaacggat gagaaaccag catctgaagc aaccacatct aaa 283 <210> 43 <211> 280 <212> DNA <213> Oryzias javanicus <400> 43 aagcagtggt atcaacgcag agtggccatt acggccgggg atgaaaaaca tggcgaacac 60 agcagggacc agcatggatg actcgatgag atacgccgaa tattccccta aaacgaccac 120 aaggagcgac gcagaaatag acagaaagct gggagggact ctgattgcag ttggactctg 180 tgctgctgct gctggttttg caggtcgtta cgccttccag ctgtggaagc ctctgggaca 240 ggtcttctct gaaactgtaa agaagatgcc ctcatcgatt 280 <210> 44 <211> 269 <212> DNA <213> Oryzias javanicus <400> 44 aggtggactt cagtttgtga catggccaac cctttaagag gggaagtgtt caggctgtac 60 aaaaatctcc tctatcttgg ccgtgaatac cccaaagggg cggcttactt cagagagcgc 120 ctcaagtccg ccttcatgaa gaacaaagat gagaaagatc cagagaaaat caaagcgctg 180 gtggctagag gagactttgt catcaaggag ctggaagctc tgtactacct gaggaaatac 240 agagccatga agaagagata ctacgaaac 269 <210> 45 <211> 267 <212> DNA <213> Oryzias javanicus <400> 45 gtcgctgcag ccttctctgt ctgactcacc cctcttcatt tgtctgcaaa catggccgag 60 gcgtttgtgg gaacgtggaa catgaaggag agcgagaagt tcgacgagta catgaaggct 120 ttgggggtgg gatttgccac gcgcaaagtg gggaacctga ccaaacccac caccatcatc 180 tccatggacg gtgatacggt gacggtgaag actcagagca ccatcaagaa cacagagctg 240 tctttcaagc tgggggagga gtttgac 267 <210> 46 <211> 120 <212> DNA <213> Oryzias javanicus <400> 46 aagcagtggt atcaacgcag agtggccatt acggccgggg acccaggaat ggaccacttt 60 ggggccgttt gaggcagaca aaacccttga attcaagaag gtcgtgacca acattggaaa 120 120 <210> 47 <211> 245 <212> DNA <213> Oryzias javanicus <400> 47 catgatgttt cggctgcctc atccccagag agatcgtcgt ttgactccgg gtgcaggaac 60 cgacagaacc agtcaaggca cgttgtcaac aaaaatgcca ttgctgccag attgaatcgc 120 ctgaagaaga aagagtacgt cagcagcttg gagagcagag ttggagttct gtctggggaa 180 aatgtcaaac tcaaacaaga aaactctcag ttgacaaagc gggtggaaga gctggaagat 240 gagac 245 <210> 48 <211> 2040 <212> DNA <213> Oryzias javanicus <400> 48 ctattcttca tgcatttact gccaaacttt gctgaatgct ggtgggatca agtcattttg 60 gacatcctgc tatgtaatgg aggggggatc tggcttggta tgactgtgtg ccgctttttg 120 gagatgagga cataccactg ggccagcatc aaagacatcc acaccactac agggaaaatc 180 aaacgtgcag tgctgcagtt tactcctgca agctggacct acgtacgctg gctcgatcca 240 aagtcttccc tgcagcgagt gacaggcgtc tatttattca tgatcatctg gcagctaaca 300 gagctgaaca cattcttcct caaacacatc ttcgtttttc ctgcaagtca cgctcttagc 360 tggtgtcgaa tccttttcat tggtatcatc acagctccaa cagtgaggca gtattatgca 420 tacctcacag acacgcagtg taagagggtt gggacgcaat gctgggtctt tggggccata 480 gcgtttctgg aggctttggc atgcattaag ttcggacagg acttattctc caaaacccag 540 atcctatatg tggtcctttg gctgttgtgt ttggccttca ttacattcct gtgtctgtat 600 ggaatggtgt ggtatgcaga aacatatggt ccaagagaaa agagcctctc tgaatgtgag 660 gacagtaatt acgctgagtc tcctgagcat gtgccagaag aatttttagg taaaacagat 720 gtggacggtg acagtcctac acttaggaga agaggaacag gctcggggaa gtccagatca 780 atcaatggct ttgacagcca atagagattg aggacaaagt ttgctgtcaa atgactctgg 840 aaatggggta aagataacac aggtataatg gaagttcaaa aaattaaaaa tgtaccccac 900 tggccatcga agagtggcat cagcagagaa caagtgaacg agctgatcca tgtagtgtta 960 tcaggagtga acagcgactt aggctaacgc agatggggtt ttccctgacg ccaaccaggt 1020 cctcaaccaa ctaattccag gtttctttga ttgaccgtaa ctatgtagga gtgaaggaat 1080 aaaaactgcc tattctagat gtgactgcat gctctttgta gctgatatta cactttcaat 1140 atggtaattg tttaaaaaaa actgtacatc tatctgactg gtgaacacca gctttaatta 1200 cagtatgttc ggttctgcac atttcactgt taaaaagcca tgattgtgaa ataatcactt 1260 ttgagtagac agaagtcctt tttgtttttt tatttacaaa catttgtcac tgattatctg 1320 tgtaatagtt gttcctgttt ttaacttgaa tatgggaaag atttaaattc aagactttgc 1380 tgtcaggatc atcagtggag atttgtttta aacacataat gatgcaaagc acagttgaag 1440 cactttgcag aatgtttcct ttaaaactgt attgatttgt aatgtttcag tatttctgtg 1500 ggccattgtg attttgagtg acctccctgt gtcaaccaac ccttttgtgg ctgctatcat 1560 tttttttctt tacattttac tgtactgaca aaagagggca attatccaca ttgttgcatg 1620 tgttgtcaac ttttttcctg ttggtgtgtt aatgacactt taaatataca actgcatgac 1680 tgattcgaat caaccggttt ggtccaaaca tgttacaaag tcgcacgcca catattgctc 1740 gtcttttgtt tttatttcac cccttgtgcc tgtcgttgca tagaaattca tgtgtgtgtg 1800 tgttttatca tttgtgcgtg ctttgtagaa catttatggt ctttaacatt gtcagtatca 1860 tctccacact gacacagccc tcatgatttt tgacaatcca gacggtggct ttgaagaacc 1920 gggctcgtgt ttgactgcag gcattataaa gggtacacac tgtttgtgga gttggatttc 1980 atgtcatttg ccaaaaaaga acaaaatcaa caaaaaagaa tattgctgtt gtgtcaactg 2040 2040 <210> 49 <211> 208 <212> DNA <213> Oryzias javanicus <400> 49 aaactgttcc tgcagaactt ctctgccggt gccagagctc tgactgacgc tgagacaaag 60 accttcctga aggccggtga ctccgatggc gacggcatga ttggagttga tgagttcact 120 gccatggtca agagttaaat ggacaaaacc gaccaacatc cgacttcaca actccaaagg 180 aacaactcaa gctgaaacat aatcctcc 208 <210> 50 <211> 203 <212> DNA <213> Oryzias javanicus <400> 50 catcgtggct gacttctcgc ggcgggcggt cgatgtctca gctgtggttt ggcaggtcaa 60 aggtcaaact ccgtgcgcgt gttgtgtggt gtgtccaccc aacggaactc gaactgtttt 120 tctgttcgat acgaaccttc ctgatgtcac actggaggac ttctctaaag tcaacctgca 180 tcagttcaag tggacgcact ggg 203 <210> 51 <211> 1657 <212> DNA <213> Oryzias javanicus <400> 51 aggcaacgga cggattatcc aggatgactt ggtggtcggc ggatacttca tccccaaagg 60 gacccagctg gctctctgcc actactccac atccctggag gaggagaact ttaccgatgc 120 cttagagttc cagccgcagc gttgggttcg aaaagacgcc tcagatcgcg ttgacaactt 180 tggctccatt ccatttggct acggcatcag gagctgcgtt ggcaggagaa tagcagagct 240 ggagatgcat ctagctctta taaggctcat ccaaaacttc cgcattgaag cgtctcctgt 300 caccactgag gtcaaagcca aaacccacgg cctgctctgt ccgtctgctc ccatcaacct 360 tcggtttgtt gacagggaaa actaaaagtg ggcctctctc cttgaaaaac tccacctgga 420 tgtttattaa ccaacttaca gagctgagac tgaggtttta ctcagacaag aaacgtctta 480 cttgtttgtt aggaaacaca aacactgcac aaatgtgagc tgtaaacact gttttttaat 540 gaatgttttt gacttggtaa aggccgatta atgactgaga cttcattcct attcaaaaca 600 ctgagtaaaa agggaattaa ttcctttact ttgaccattc gttgcaggtt aaggagcctc 660 caagtaaatg agaatgtgtg accatgtgtt ttgtaattac atgtacttca acttgtagtt 720 tgtcaaaggg cagctgtaaa tgcattcaac attagctgtc taaggttgag gtgtgccaag 780 ctttatttac cgataatgct gtttctctgg cagaccaaag taaaaggctt ctttttcatt 840 tggcaccata atcactaaat atgttcaaat ttagaaggca ggcattgtaa aactaaccac 900 attatatcta ttcttcatct aaattcaagt ttttagtaaa acattttgat cgtttttaaa 960 ttatgaaata atattcattg aacaataaat aaatcttaaa tgtatgtatt ggtttacaga 1020 attgaggatg tgtttgtcat gctcagatca cttggattac agaatgtgtt gagtaatctt 1080 gggtaatttt taccatttgt gagcatcatt ttataaggaa aacgcatgtc tgggaatgaa 1140 tcactaaaaa gggaaaagca aagttatgag gatcatgctg tgaacatgaa ggaaactgta 1200 aacattttgt atattttttt atatcttgtc tacttgtttg tttcttctta gtagctccag 1260 tgaaactgga acataataca cctgtatatg ctattgtgtg ttgttctctg agaagacttt 1320 tcagttctta ttgttcaaat gtcactccta aggcagtcat atttttctaa agcaaaaact 1380 gaaaataatg ttatatccaa tgaaatcaaa caaacacaaa cttttgcagg ctaaatatgt 1440 gacaccaaat ccatttgtta agagatgcaa gatcagaaaa ctcctaaaga caaaggggaa 1500 aaaatgatgt aagatcatct gacgtagttg gtgactttta tgtgtcgctt tcattatgtg 1560 cttgtgcaat aggacacatt aacattaccc aatgacaagc aaaaaaaagt gtatatttat 1620 gctgaaatct ccaataaatg caagtttgaa gaatact 1657 <210> 52 <211> 203 <212> DNA <213> Oryzias javanicus <400> 52 accgaggaac attacaggct gaaaggaggt atatggaaat ggaggaccag atggaaagcc 60 agaagagaag acaagaaagc aaagatgctt tgatctctga gcggacgggt tctttgggat 120 gcgtcggatg gtttatcgtc atcctctctg ggttcttcac agttcttctt tttcccataa 180 ccatctggtt ctgtttgaag att 203 <210> 53 <211> 199 <212> DNA <213> Oryzias javanicus <400> 53 tctgaagcca aaaaagaaaa atgcccaaca agaagcagcc aggcgcagag atgaagtgcc 60 tcagcgcccc ccaggaggac gacagcagca ccaacagcag cgagttcccc taccccacct 120 ttgtcaagaa agttcctctg gaggggccat acccagagtt tgaccccgag tgtcagaact 180 tcctgccgga gcacagcac 199 <210> 54 <211> 1638 <212> DNA <213> Oryzias javanicus <400> 54 aagcagtggt atcaacgcag agtggccatt acggccgggg tcagtttccc tgagtgccag 60 aggtgacctg cgagaggact ccctggactt ggacaccatg atgcagcggg ctttgttcag 120 caggagcgcg ctgctcgctc agcaggctgc ggcggctctc gacggcgcgc tgctcgggag 180 gagcgcgtct gcgctgcagc gcgtggagcg ctccatgtcc tcggtcacca ttccgcctcc 240 agcctgcatg ctccggccac ttgaagtccc catgcgttat ctgttcggac cgggaccctc 300 gaatgttcct ccacgagttt tggcctcggg ttccaggcca atcattggtc acctgcatcc 360 agaaatgtat cagatcatga acgacatcaa aaaggggatc cagtacgcct tccagacaga 420 aaataacatg accatagcga tgagcggctc cggccacgca gccatggagt gcgcggtgtt 480 caacgtggtg gagcccggag agagcgtcct ggtggcgatc aacggcatct ggggagagag 540 agtagcggaa attgcagaac ggatgggtgc aaatgtccac acaatagtga aaacgcctgg 600 aggatattat actaatgaag aaattgagca ggccattcag aaacacaagc ctgttttgtt 660 tttcctcaca catggagagt cctccgctgg tctctgtcat ccagtagatg gcattggaga 720 catctgtaga aaacataact gtctcttcct ggtcgacaca gtcgcatcac ttggagcagc 780 accgattttt atggacaaac aaaaaattga catcctgtat accggttctc agaaggcact 840 gaatgcacct cctggcacag cgcccatctc ttttaatgac agagcatgcc acaagatgtt 900 caacagaaaa acaaaaccag tatcttacct ctttgatatg acacacctgt ccaactactg 960 gggatgtgat ggaaatgcag ccagagcata tcatcatacc gggccggtgt ctggattctt 1020 cgccctgagg gaaagtttag cgattcttgc agaaaagggt ttggaggagt cctggaggaa 1080 acacaaagag gtggcggcct acctctacaa agggctggag gatctcggtc tcaagctctt 1140 catccctgat agggatatga ggcttccctc cgttaccaca atagcaatcc ctgaaggtta 1200 cgactggagg gagatgctga gctacataat gaagcaccac cagatggaaa tgacaggagg 1260 actggggcct tctatcggca tggtgatgag gatcggatta atgggataca actgtgaaaa 1320 gagtaacgct gacaaagcac ttcatgccct ggcagatgct ctgaagaact gcaaaaagag 1380 caaagcctaa gagctcacat ccccagagtg ctgactgtca gtccatcaac aaaacaataa 1440 gtgtctcctc gtggaagaca gatgagacaa tgtaaaaaaa aataaaatgg taatttgtgg 1500 ttttctcccc aaggatttta gaatagtctt attgtaaaaa ttggttaaat agtttagttt 1560 tgaaaataaa aatattgata ttgtcatatg actcatgctg agtgcactta caatgtcaat 1620 aaagccatta ttttatac 1638 <210> 55 <211> 164 <212> DNA <213> Oryzias javanicus <400> 55 caatggggaa ttaaacgcag gactcaaaaa gaacggacag aacatgtttg caatctacca 60 gaaggcagga acacaggctg gcacctcaaa cgggatggct ctggaactgg agctgggtga 120 ccgggtctac gtccagattt ggccaaactt gaccgtggcc gacc 164 <210> 56 <211> 1620 <212> DNA <213> Oryzias javanicus <400> 56 aagcagtggt atcaacgcag agtggccatt acggccgggg gttctagcgt gaaaagggcc 60 ttctgcttct acacggcgtc gggttttttc ccccgaaaat aatagtagaa ttgtctctca 120 actaacgaaa tatggacaaa atgaaagaac ccatccaact caggcgtcaa agaaagctta 180 tcataaaaag aagttgagaa tgccaagtgg ggacttcaag gaggacaggc ttacaacatc 240 agcacaatcc accacgagtg ggacccctcc agtcacccct tctgtcaccc ccagtgtcac 300 ccccactgtc agtcccctct catcaccagc tgttcatcga aggaactggt tccacctcag 360 cccgacacct tttttcgctc ttccggagcc tgacagacac catccgaaca cagacatggg 420 aggaaacgag ggaggaggcg gaggcttaga caagtggagc tttttcggaa gtcggtcggt 480 ggtgcacaag tcccccactg atccaggctc cgaaaccagc acaggctttt cactacagtc 540 gtactttggc cttcagaagt cctccaccat ggatggcacc aacagccaaa tcactctcaa 600 ggttgacgaa ccccccaact ttatgccccc caagcctgaa atacctggca ccgataagcg 660 agtcccccag cggccgcaca aactcaagcc tcgggacatg aatgttttaa caccatcagg 720 cttttgaagt gcgaccagat attcttccat ctaaagttca actcattcca actacagggt 780 tactcatttt ctattctgtt gtcttgtgct tcatctgcct tcctatgaac tccctaaggc 840 tgacggaacc atcctcagtg ctagtcagcc gtagagatgg tccaaaagaa aatttaaaaa 900 agtaatttgt cctctttgaa gataaattaa cattcttttc tcttcacttc atttccctct 960 ttcgttcaca gtggtgtaat acgtgacgtg aaatacgtcg tcagtgcctg gaaaactaca 1020 actgaccaca tatttcatag tgccatttgt tttctgagtt ttaccatttc atataagcta 1080 actcatttat tgttgacttg tgcttttcgg tcagtatgca gcttagtgta tgactgatat 1140 tgtgcctggt ctcgcagggt gaagtgtttg ttttttttga ttttttttaa ttcccttgct 1200 catgttttta taatgtgaaa gaacatcttt taattattct cgctagcaag gcctgacttc 1260 ctgatataga tatttttaaa agcattagct gttttaatat tggtcaactt tcaaatgagc 1320 tttgtgttcc aaatagcagg ttgaacagtt tgtttacttt tccagagaat tacagtgttg 1380 gttcagctgc aacagaatca aacagagctt attttccttt ttcttcatag ttattgtttt 1440 attgttcttg tgctatccaa ggactgaact atgttttttc tctggtgaaa attgattttc 1500 attaaattat tgcacaaggg agttatccca gttttttcat cttaaataaa tctgccaaca 1560 actaaaaaaa caaaaaaaaa aaaaggccgc ctcggccact ctgcgttgat accactgctt 1620 1620 <210> 57 <211> 123 <212> DNA <213> Oryzias javanicus <400> 57 tttcatcgtg gctgacttct cgcggcgggc ggtcgatgtc tcagctgtgg tttggcaggt 60 caaaggtcaa actccgtgcg cgtgttgtgt ggtgtgtcca cccaacggaa ctcgaactgt 120 ttt 123 <210> 58 <211> 122 <212> DNA <213> Oryzias javanicus <400> 58 aagcagtggt atcaacgcag agtgccatta cggccgggtt ggtctctccc agcatcatcc 60 ggaccagctt cacgatgttc tgaccctccc acaccatggc gaagaggggt ccagaggaca 120 tg 122 <210> 59 <211> 120 <212> DNA <213> Oryzias javanicus <400> 59 aagcagtggt atcaacgcag agtggccatt acggccgggg acccaggaat ggaccacttt 60 ggggccgttt gaggcagaca aaacccttga attcaagaag gtcgtgacca acattggaaa 120 120 <210> 60 <211> 111 <212> DNA <213> Oryzias javanicus <400> 60 aagcagtggt atcaacgcag agtgaccatt acggccgggg actaacgttg gtcagttttg 60 ctccttatga gtggttcgag gagtggaagg acgagaaggt gaccaacagg a 111 <210> 61 <211> 1597 <212> DNA <213> Oryzias javanicus <400> 61 aagcagtggt atcaacgcag agtggccatt acggccgggg gcggacgttt gtcgtgaact 60 ttgccggtgt gcaactaccc ctagaccctt aaccgtccgc agtatgggca gtgtattggc 120 tgccacctcc cccagcccga ccccagctgt agcagctggt ggtcaggggg tgcctgggct 180 ggtgtcagtc cctcctgggt tcaccatgcc tcctgtgtcc cccgttcctt ccacaactga 240 atctggacag gaggcagcag acacagattc gtcccttcct aaccccggca cgtatgaaga 300 atgccaccgc aaatgtaaag aggttttccc cctgcaaatg gaaggggtgc gtttagtggt 360 aaacaaaggc cttagcaacc actttcaggt tagccacact gtgaccctca gcaccctggg 420 tgactccggt tatcgatttg gctcgaccta tgttggcaac aaacagacgg gacctgctga 480 gttatttcca gttttagttg gagacatgga caacactggc agcctgaacg ctcagatcat 540 ccaccaacta accaaagccg tacgctccaa gatagctatt caaactcagc aacacaagtt 600 tgtgaactgg cagtgtgaca tggaatatcg cgggaaagac ttcaccagtg ctgttacact 660 cggaaatcca gacgtgctcg ttggatctgg tattgtagtt gctcactatc tccagtcaat 720 cacgccggcc ttggctctgg gaggagagct ggtgtatcac aggagaccag gcgaggaagg 780 gaccgtaacc tctctgctgg gcagatacac gggtgacaac tttgttgcta ctttaactct 840 gggaggagct ggagctcatg ctacatacta ccacaaagcc aatgagcagt tgcaggttgg 900 ggttgaattt gaagccagca cacggatgga ggacaccacg acatcttttg gttaccagct 960 ggatctcccc aaagccaact tgttgtttaa aggcacagtt gacagtaatt gggtggttgg 1020 tgcaaccctt gagaagaaac tggtgccgct ccctctcacg ctggccctcg gtgctttcct 1080 caaccaccgc aagaacaagt tccaatgtgg gttcggcgtc accattggct agaagcgccc 1140 cagctgccct aatccggctc acaggctgca gcccggaccg gcagacacac acaggaaacc 1200 tggactaagt tttaagaatt ggatacagag actctcttac aactgagatc ttgaggccgg 1260 acagagagac attttccaag gagccagaac tggccaagcc atgcctacat actgtagcac 1320 acgtctttcc tgtatggtgt tttgaaggct agaatcataa atagcagagg gattcaagtc 1380 acgcatgaga acatgtgttg taaagtaggt ggtgagacat aatatatggt tgtcatgtaa 1440 ggattgaaat aaatgtgata acattttttt tacaactgga tgttgagttc atgttgttca 1500 ttagcataga gtgtttataa agaactaatc atcttgtctc cagatcttta aaaagtctta 1560 aattgaattt tattaaggta aggctttaaa aaaagaa 1597 <210> 62 <211> 1555 <212> DNA <213> Oryzias javanicus <400> 62 aagcagtggt atcaacgcag agtggccatt acggccgggg gatcagcttt tgttgttaaa 60 atggaggttg gcctctcgcc ctgagtcgat ctccttcctg gccaaggttt aaatgttgaa 120 atgcaataaa tctggagaca ggatggttgt ggacgcaccc aattccaacg ggccttttca 180 accggtggct cttatgcact tcagagatgt ggcccccgcg gaacaagaga agctcttcat 240 ccagaagctg cggcagtgct gcgttctctt tgacttcctc tccgaccctc tgagtgacct 300 gaaatggaag gaagtgaagc gagcggccct gagcgaaatg gttgagtaca tcacccacaa 360 caggaatgtc atcacagaac ccatctaccc cgaggtggtg cacatgtttg ctgtgaacat 420 gttcaggacg ttgcctcctt catccaaccc caccggagca gagttcgatc ctgaagagga 480 cgagccgacg cttgaagcgg cctggcctca cctccagctc gtctatgaat ttttccttag 540 atttttagaa gcgcccgatt tccagccaaa catagcgaag aagtacattg atcagaaatt 600 tgttatgcag cttctagaac tattcgacag cgaggatccc cgagagaggg acttcctgaa 660 aacgactctc caccggatct atgggaagtt tctgggactg agggcgtata tcagaaaaca 720 gatcaataac attttctata ggtttatata cgagacggag caccataatg gaatagctga 780 actactagaa atacttggga gtataatcaa cggatttgcc ttaccactaa aagaggagca 840 caagattttc ctgttaaaag ttttattgcc tctgcacaaa gtcaaatcac tcagtgtcta 900 ccacccacag ctggcctact gcgtcgtgca gtttttagaa aaagacagta ctctaacaga 960 accggtagtg atggctctac taaagtactg gccaaagact cacagtccca aggaagtgat 1020 gtttcttaat gagctggagg agatcttgga cgtcatcgag ccctcggagt tcgtgaaggt 1080 tcaggagcct ctcttcagac agctggcaaa gtgtgtgtcc agtccacact tccaggtggc 1140 tgaacgagct ttgtactact ggaacaacga atacatcatg agcctcatca gcgacaacgc 1200 ggcaaagatc ctgcctataa tgtttcccgc tctgtaccgc aactcaaaga cgcactggaa 1260 caagaccatc cacggcctca tctacaacgc tctgaagctt ttcatggaga tgaatcagaa 1320 actctttgac gattgcacac agcagtttag ggcagaaaaa aacaagaaaa agctaaatca 1380 aaggaacgtg aggaagcttg gatcaagatc gagaacctcg ctaaatccaa cccacagctg 1440 cagcacgagc agcggaaaga gcgggctatg gtgcggcgca agtctgagtt gcctcaggat 1500 atttacacca caaaaagcct tggagtccca ccgcagagct gaagaaatgt taaac 1555 <210> 63 <211> 1515 <212> DNA <213> Oryzias javanicus <400> 63 tcccagcaac acctgtaggg aagagtgtgg atcattcctt tatcacctcc aaagctctta 60 ccaacggcag ccccgccctc acgccctctg caagaatctc agcacttaat attgttggag 120 atcttctgag aaaagtcggg gctctagagt ccaaacttgc agcttgtagg aactttgcca 180 aagaccaagc agccaggaaa agctactcca ctgacaaggg cacgctcatc aacagcaacg 240 ccaccaagtt ctcgcactca atccacacga cttactttga taaaaccact gtcaatggac 300 tggaccccag ctctctgacc tccatggccc catccagagc cgtgtctcct cccggcatgc 360 tgcctttaag tgtgtgaggc tgctgaaacg cctgcccagc caccacggcg cggcgacgaa 420 gaggacagct gtgtgcgtgc gtgagagagt gctcgctcgc tcgcctgctt aagagtttga 480 gtagaattgg ctaaaattca tgttgcagct ataggtgcat ccgtgcttgt gctccttcca 540 catgcgcatg cgcctgcagc tgcactgtgc tcgagtggct gtcattgcaa tgcgcttaac 600 ataaaaaaaa aatccagatt ttcctgacaa aggtcctaaa cagaccacag cttcgtttaa 660 agctcccttt tttctaaacc gcacagttaa actattaaga atgtatgata tttaaaaggg 720 aaacgttcat ctaaactaat ttatctgaga gtctgattcc aaacgctgtt tttctacctg 780 aagttttttg catgtttgtt aagagtgttt actgaagtgc gaatgaccga cgtgaatgtt 840 gacggttctt ggccgcgcgg tgcaagcgtt cctcccgttc ctggctggaa gaagaagaag 900 ttctgaattc ccctcagctg tgtgtctcct ctgcactgaa agaagctgct cctcacaggt 960 ttttggttgc agtggaggtg gttctcgaca tcagctgacg tatttaggaa aacagttatg 1020 tccttttttt ttattgtttt gtgtggatgt tggaagctca ctgtgattcc tcacttacaa 1080 acaacagttt gtgttactgt cccaacatgt ttgccaggtg tagcttcatt tatggttctt 1140 tgctgcgtca cagcagtgca gctaatcttt ctgttcagta ttaattttgc tatatcccct 1200 ttagttttct attttgattt tattttacgc acaaaaactg tatccgcatc catttattta 1260 ttatcaaagc ttgcaagacc attaaaaagt taatattcct gggtgttttt ttgagaaggc 1320 gccctcagag gctgttacgg ctgcagtcac tctgtacgtt tctttaccac tgtacatctg 1380 gcattataga gtcctattta tttctagatg ctgttggcat gtgttccaga gaagttttac 1440 taccatacag tggttacatt gtataataaa gtgtttgttg taatgttaaa ataaataaag 1500 attcagatta ttaaa 1515 <210> 64 <211> 1485 <212> DNA <213> Oryzias javanicus <400> 64 tcgtagacga aggccagatc ttctccctcc tcagcgctcc tcttgatctc taagaagtca 60 ggatgcctca cgcatacccc ttcctcactc ctgagcagaa gaaggagctc agtgacattg 120 ctcaaaggat cgtcgccccc ggcaagggaa tccttgctgc tgatgagtcc actggcagtg 180 tagctaagcg cttccagagc atcaatgctg agaacaccga ggagaacagg aggctgtacc 240 gccagctgct cttcaccgcc gacgaccgca tcgccccctg cattggcggc gtcatcctct 300 tccatgagac catgtaccag aagacggacg atggcaaggt cttcccacag tacctcaagg 360 agagaggcat ggtggtgggc atcaaggtgg acaaaggtgt cgttcccttg gctggaacaa 420 atggcgagac aaccacccag ggtcttgatg ggctgtatga gcgctgcgcc cagtacaaga 480 aggatggtgc tgactttgcc aagtggcgtt gtgttctgaa gatcaccccc accactccct 540 cacatctcgc catcattgaa aacgccaatg tcttggctcg ctatgccagc atctgccaga 600 tgcatggcat cgtccccatc gtggagcctg agatcctccc tgatggcgat cacgacctga 660 agcgctgtca gtacgtcacc gagaaagtct tggctgccgt ctacaaggcc ctgtctgacc 720 accacgtcta cctggagggt actctcctca aacccaacat ggtgactgct ggacactcct 780 gctcacacaa gtacagcagc caggagattg caatggccac tgtcactgcc ctgcgccgca 840 ccgtgccccc cgcagtcccc ggaattacct tcctgtctgg aggccagagt gaggaagaag 900 cctcagtcaa cctgaactcc atgaaccagt gccccctgca tagaccctgg gctctgacct 960 tctcgtatgg ccgtgccctg caggcctctg ccctgaaggc ctggggtggc aagaaggaga 1020 atggaaaggc gtgccaggaa gagttcgtca agagagcttt ggctaacagc caagcctgcg 1080 tgggcaaata tgtttcctct ggagccagcg ctgctggtgg agagtcattg tacgtagcta 1140 accatgctta ctaagcactg acgccccact ttcgacccac cgcctctgca acagaacagc 1200 acacgtcctc aaagacaatg cttttaaagc tgtctctcca ctatcactgc aactttagta 1260 actttagtaa ccaagaaata tgaaaccaaa tgatgagaaa aacctttctt ctagcggttg 1320 ctaaacaagt tctgacttca ttcccttacc ttttattttt aagcgccttt tttacaggtg 1380 aaaatttcca ctgtttttac acagctcttt ctactttcct tggtctgttt ccaccttaat 1440 gcagcatgta acgtatgctg ttaccacgga ataaagtctt taccc 1485 <210> 65 <211> 1481 <212> DNA <213> Oryzias javanicus <400> 65 gagaccaact tcttctcccc tctgaagcct ctcgactgac ccttgcgtcc caccatgtct 60 ttcatccaag ccttcatgca gcaaacagtt tatctgggca tgcctgatga ctcaactctc 120 aggaatgagg gaactgtgac tgcagctccc aacttcagcc caagcggaga tgcagcagtc 180 ctggataagg ccatcaagac aaaaggtgtg gatgaaaaca ctattattga aattctggtc 240 aaaagaagca acgaacagag gcagcaaatc aaggaggcct accagcaggc gagtggcaag 300 cctctggaat ctgctctgaa aagtgccctg aagggagatc tggaggaagt ggtgctggct 360 ctgctgaaaa caccagccca gtatgatgcc cagcagctga aactggccat gaagggtctt 420 ggaactgatg aggacaccct gattgagatt ctggcttcca gaaacaacag acagatcact 480 gatttgaaaa aggcctacaa ggaagattac aagaaggacc tggaggaaga catcagatct 540 gacaccagtg gagacttcag agctgctctt cttgctctct gcaaggccgg cagaactgaa 600 gggatcagtg agcaactcat tgacagcgat gccagggctc tgtacgaggc tggggagggg 660 aggaagggca aggactgctc cgtcttcatc gaaattttga ccacgagaag tggcccccac 720 cttcgcaaag tgtttgagcg gtatgcgaag tacagcaaag tggacatggc taaagccatt 780 gacctggaga tgaagggaga cattgaaagc tgtctcacag ctctcgtaaa gtgtgccgga 840 agcagatctg gattctttgc agagaagctt tacctggcca tgaagggcaa aggcacccgc 900 aagaacatcc tgactcggat catggtgagc cgatctgaga tcgatatgaa actcatcaag 960 gcagaataca agaaaaacta cggaaaaaca ctgtacaaag acatactgga tgacactaaa 1020 ggagactacg agaagatcct gctggctctc tgtggaggag ataactaaaa tcacgtcaaa 1080 gagatccaat ttaaagaaca atctcctgtg atgtcccttc acttgcattg cgcccaatgt 1140 aataccaagc agacagcttt ttggtgactg tcttgacaat tagcaatcag taaaagatta 1200 gcattgccaa atcacatata ttctatgcaa gttgttcagt gtcaaaccaa agcatttcag 1260 catagacatg aaatcactag attatctgtc ccatgctgca cacatacagc tttatgcgct 1320 tgtgcgtgtt taaagagaag cattcagatc accacgtgcc aaatttcttt agagtcagtg 1380 ttacccttga aggagctttg acatttgcaa ataaaagctt tttctaacaa aaaaaaaaaa 1440 aaaaaggccg cctcggccac tctgcgttga taccactgct t 1481 <210> 66 <211> 1477 <212> DNA <213> Oryzias javanicus <400> 66 aagcagtggt atcaacgcag agtggccatt acggccgggg acggggaaaa gcagaagttc 60 tgtccagtct gtggaactct gtatttagtt gaaaataaaa aatgttgagg caggttcttg 120 tagcgtcact gtggatctgt tcttttgacc tcggcttagc tgaggacccc cacttgaaca 180 gggcttacca gctgatgtct gagaccccac tcatcgacgg ccataatgat ctgccttggc 240 agcttcgaaa gctgttcaac aatcagctca acacagttga tcttaacaaa ctggaaggaa 300 cgcacaccaa cattcctaag ataaaacagg ggcggcttgg tgcacagttc tgggcggctt 360 atgttccctg tgaaactcaa tacaaagacg cggtcagaca aacgctggag cagatagatg 420 tgattcacag gatgtgcgag aagtatccag acactttcaa gtttgtcacc acgagccaag 480 gtatcttgga tgccttcatg gagaataaaa cagctagcct gatcggcgtg gagggaggac 540 actctattga cagcagcctg ggtaccctgc gcaccatgta ccagctgggg gtccgctacc 600 tcaccctgac acactcctgc aacacaccct gggcggataa ctggcgtgtt gatgctggat 660 cagacccggt tcagagcaac ggcctgtcac cttttggaaa gcaactgata gttgagatga 720 accgtctggg gatgctgatc gacctcgctc acgtgccggt gtctgtgatg aaccaggccc 780 tgaccctgtc tgcagctccg gtcatcttca gtcactcttc tgcttacgcc gtgtgcccgc 840 acagccggaa cgttcccgat gaggttcttc tcaaagtgaa agagacgaga ggaatcgtga 900 tggtgaactt ctacaacgat tacgtgacct gcagccagaa agctaatatc tcagatgttg 960 ctgatcactt tgaccacatt aaaaaagtgg gcggggctaa aattattggc tttggcggag 1020 attatgacgg agtcaccaga gtgccagacg gtctggaaga tgtgtccaaa gtgccaaatc 1080 tggtggctga gctgctgagg agaggctgga ctgacgagga tgtcaaagat gctcttggaa 1140 ataacctgct ccgggtcatg agcgaggttg agagggtccg tgataacatg aagaaccagg 1200 tgccggatga tgttcccatt ccgtacgctg aggtggagaa cccctgcagg acgagcttcg 1260 gttacacaga tgctggagct gctcattcag tcagcgcagc agcccttctg ctccctctgg 1320 ctctgcacgc ttccatgttt actaattaag acgctcatca gagctgatta gtctgaaatg 1380 ttcaaatcta taaagttttt tttgcatctg ttgttttttt gatagaaatg tttcgcattt 1440 tgttgctaaa aaaaaagaat aaagtgacaa tctaagt 1477 <210> 67 <211> 1477 <212> DNA <213> Oryzias javanicus <400> 67 actcgtgctt gtgtagccac aatgatgaag ttcactgcgg tttgccttgt ggtgctggcc 60 ctgcttgacg gcttttgtga tgctcagcct ggctttggta aacctgcata ccctccacct 120 gggagtaaaa agccacctca agatcctgtc cagcaaaagc tgattccaga aaaagagctc 180 acctggaaat atcctgctga ccctcagcct gaacccaaac ctgtaggacc actcgagcag 240 agatatcctg ttcctgctgc tactgttgct gttgattgca gagaagattt ggctcatgtt 300 gaagccaaaa aggatttgtt tgggatcggc cagttcattg acccagctga cctcactctg 360 ggaacgtgtc ctgctgtagc tgaggatcct tcggctcaag tgttgatttt tgaatctgca 420 ctgcagaatt gtgggagctc gttgacaatg acagaggact ccctggtcta caccttcact 480 ctgaattata accctcaagc cctgggcagt gctcctgtag tgaggacgag tcaagctgtc 540 gttattgtgg aatgccacta cccaagaaag cacaatgtga gcagtctggc tctggatcct 600 ctctgggtgc cattctctgc agctaagatg gcagaggaat tcttgtactt ctctctgaaa 660 ctcacgacag acgacttcca gttcgagagg ccaagctacc agtatttctt gggagacatg 720 atccacatag aggctaccgt caagcagtac ttccatgtgc ctctgcgtgt ttacgtggac 780 agatgcgttg ctactctttc acctgatgca aactccagcc ccagttatgc cttcattgat 840 aactttggat gtatgcttga cggcagaatc acaggttctg actcaaagtt cgtgtctcga 900 ccagctgaga acaagcttaa cttccagttg gaagctttca ggttccaggg tgctgacagc 960 ggaatgatct acatcacctg ccatgtgaag gcgacatctg ctgcttatcc ccttgacgct 1020 gaacacaaag cttgctctta cgtcaatgga tggagggagg tcagtggtgc agatccagtt 1080 tgcgccccct gtgagtcgag tggatttacg gctcatacca atacagcagt atcacctggc 1140 acctcaatta ttagtggagg cggtcacgga tctggaaaac cttcagaccc ttcaaggaaa 1200 gttcgtgcag catccaaatc tgaagttctg gaatggcaag gcgatgtcac tctgggtccc 1260 atccccattg aagaaaggag gatctaatag gcatatgtgt aacatagtct cctgctgttg 1320 caatgatcat caaaataaac acttgcattg gcttatactg ctctatctag cctttcctca 1380 actttatatg ttcaaacttg tcaaaaaaaa tttaaagtcc caacaacttc attaaagcaa 1440 gaaagatgtc taagaacgag gtgtgatttt tttttac 1477 <210> 68 <211> 1454 <212> DNA <213> Oryzias javanicus <400> 68 aagcagtggt atcaacgcag agtggccatt acggccggga agaaccgcag cagtagcagg 60 aaaaggcggt gaagaagtac aacgacgata atgctaaacg gaaaatagaa aggacgggtt 120 ccgttgggcg cacgttaaat caacgctttt acctcgaaaa aaagacattt gaacattggg 180 gcattatatt agctgaacta tgacagagcc tcagtcggcg ctcttactca ggagacagct 240 agcagagctg aacaaaaacc cggtggaggg attttctgct ggtctgatag aggacagtga 300 tctttacaga tgggaggttc ttattatcgg gcctccagac acgctgtatg aaggtggtgt 360 gtttaaagct catctgacgt ttcccaaaga ttaccccctc aggccaccaa aaatgaagtt 420 tatcacagac atttggcacc caaatgtgga caagaatgga gacgtatgta tttctatttt 480 gcatgaaccc ggagaggata agtatggcta tgagaaacca gaggagcgat ggctgcccat 540 ccacacggtg gagaccatca tgattagtgt tatctctatg ctggcagacc caaatggtga 600 ctcaccagcc aacgtggacg ctgcaaaaga gtggagggaa gacagacacg gtgcattcaa 660 aaggaaagtt gcccgctgtg tacgaaaaag ccaagaaact gcattcgagt gatctctagc 720 aaggatttag ttcatgtttt cagggtctcc tattgaaatc agaatggcac tgtttcctgc 780 actcctatca tgtctccagg cctgtccttt ttggagggaa gagactggct tctgcaggct 840 gcagcattat cctacagtga cgagcaaggc tgacagaaaa tcgccaagca agtgccaaat 900 ttaaaaaaaa taaagtaaaa aaaataaaca aatgcccaga ggatgtcaac acattcttca 960 agtctatgaa ctgcttctac tttcaggaag atattgtaaa gacatgtaaa tagccaacct 1020 aaaccggata atatataccc tcctttccat tcatcaagac atttagacca aatatatagt 1080 actggttggg atagatttat ttttgtgttt ttcttctctc aactccagca tgtattagct 1140 gtctttagtt tgttttcatt ggagttttta aagagaataa atcacaatgc tgtgggagga 1200 aaaagcacca gtgaagatct catcgtgttc attgaagacg ttcccgagga acaccgccac 1260 gttctgttct cgtaggttct cacaacactc ttctattcaa acctgtatgg tttcctgatc 1320 actttttaag tctttccatc cttctaagtt caagacggag atggatgatt tgtgcatgcc 1380 caacttaggt tgtttttaaa agtgcctcct aataaaaatg cttggccagt tcaccccaaa 1440 ttaaacaagt attt 1454 <210> 69 <211> 1407 <212> DNA <213> Oryzias javanicus <400> 69 aagcagtggt atcaacgcag agtggccatt acggccgggg gaagctcaaa ggcaaagaag 60 aagagccgaa acaaaacacg gaagttgtgt ttgtgaagtt gtagatacac aacggcatgt 120 gtaaaacaaa agccatcctt tcaaagtggt ttgtgtttca gacagctggt gaacgtgatg 180 ttcaacagat cgtatcagcc gctccctcag agagactcga acactcagag gagctccggt 240 ttgtctgtgg acttccgcta caataaagga ctgtcctttg attatatccc aaatgtttct 300 gacaacgact ttactgatac ctcacaggga tggttttcct ggatttgcaa cttgattgtc 360 accttccttg tttttacctg cacttttata acatttcctc tgtctggatg gtttgttctg 420 aagacagtgc ccaactatca gaggatagta gtgttccgcc tgggtcgaat ttgccctcca 480 aaggggcccg gtattgtatt tgtgctgcct cttattgacc agtggcagag ggtggacctt 540 cgcactcgcg cctttaacat cccaccctgt caggtggtca ctcgagatgg cggcgtgctt 600 ttggtgggag cagacatcca gtttaggatc tggaatcctg tgatgtccgt tgtgtccgtt 660 caggatctaa acgcttccac caggatgacg gctcagaatg cgctgaccca cagcctggcc 720 aagaagacgg ctcgggaaat ccagactgag agggtgaaac ttgaggaata tctcggggtg 780 gacataaatg agatgactcg tccttggggt cttgaggtgg atcgagttga actgactttt 840 ggttctcttg gaaaagcctt agaagacgta gccgttgcac cgctgtccat ccttctgctc 900 ctggactaga aggcctcgct ggccccattc agcagctggc catgcagttt ctgagcccca 960 gctgcccttc acagcccact caagacagcc tcacattcac agacgagcgc cacagtggct 1020 cagaatctgc aactgccaca cctggttctg tggaggagct gctcagcggc gtccagaggt 1080 tgctctccga gtctttggtc cgccatgttg gagccagctt ccagtttgag atcagctcag 1140 tgaatgggga acagcacaga taccatctgg acctcagcca gggcaccgga accgttggat 1200 ctggacctct gctgctagag ccggatgtca ctctgagcat gagcgatggc gacctcctgg 1260 ccatgttcca gggggggcgt acagccactt gcggcctaca ccagtgggag actgaaagtt 1320 cagggggaca tcagtacagc catgaagctg gaagaagtca taaagctcct gaagaaacaa 1380 tcagaatcat ttgtgtttta atattta 1407 <210> 70 <211> 1407 <212> DNA <213> Oryzias javanicus <400> 70 aagcagtggt atcaacgcag agtggccatt acggccgggg actcagacac agaagagaga 60 aggatgaagc agctggtggt tctcacctgc ctggtgtgtg tggccttcac acaggagacg 120 gtcatcgacc ccagaggagc tcgaccggtg gaacacggaa ccagagacga gaaatgtgcc 180 acgcagaagg aatggccgtt ctgtctggac gacgactggg gccacaaatg tccctcaggc 240 tgcaggattc aaggcctgat ggataaatac gaccacgaac tgctgaagaa gctcgagaac 300 atccgccagc agctgaacct gcacaagggg aagtttcgct ccgcagacca ggggtccaaa 360 cagacccagg agtacctgag ggagaagctc acggtggatg caggttatga caacagatac 420 tatgaactgg cccaaactct tcgtcagaga atcacagaca taaaaatccg gattgacaag 480 cagatgaaag tcatgtccgc cttgaagatg cagatcaggg atcaggtcac ggaaatgcaa 540 aggctggagg tcgacatcga catgaagctc cgcgcctgta agggatcctg cgcaggatac 600 cacgagtacc aggtggaccg ggagagctac gtcactctgg acaagcaggt gacccagctg 660 gactcgcagt cgccacagaa catcgaagca gcggggacgc tctacgtgat gaagagcagg 720 ccgctgcagg acgtgctggt ggacagcatc tacaagacca aggctgtgga cggccagcag 780 aggcaggaca tgttcagtga cattaaaacg ctccagctcg tcctggaaaa cgaaggttcc 840 agttcgtccc ctgctactgt ctccaaagag ccaggtactt ctttcccgtc ttcatcgtcg 900 tcgtcatcat caccctccct cctcccctct ggttcctcca atccgtccaa gtccatcact 960 gagcttgggg gacgcggcga cggggacatt tttggtgggt ttggagggtt tgacggtttc 1020 ggtcagccca gtaccggcag tgtgaccaca aaaagagtca gctgcaccag taccgtaaaa 1080 aaagtggtgg ttcacaccaa ggacggcccg gtagaacggt acgagactgt aactgaagga 1140 ggacccgggt gcatagggac ggacatgacc aagggtggca tgggttccct gttccccagt 1200 ctgagccacg cctccacaac caaaacgggc ttcggcagta gcaagggaag cactttagga 1260 aatccctttg atagcgacgt tgggatcgac ctcggagcct tcatgacaga caacgcagag 1320 gacgacgttc cggatttcca cgcccggagt gtaaagagcg ccaacgtcga cctgcaggcc 1380 gattatgtag gaaaaggtac cagaacc 1407 <210> 71 <211> 1391 <212> DNA <213> Oryzias javanicus <400> 71 agtcttctgc agcgaggtag gaacctggta caagcactca gccagaagat agaaacgttt 60 ggagcggctg aagtactctg tgttcagcaa agatttcagg ggattatagt ctttcagctg 120 cttctgtttt tacgtccagg ctctaaagag gacagaagaa ccacagaaat ccagaggagc 180 aatttctgga gaacgcgagg aggagacaat gacttcgtga cgaggaagta tgtcactgtg 240 ggctttcccc gacaagcagg aagatatttt atagtggtgg gactctaaag gtgtgcagaa 300 ggcaaatcag ccgtgaatgc tgacaagcag ctgaagctgg aagctgaagg agagcaaccg 360 ccgtggcctt ttggagctgt ctgactgagg agaatcggct tctggatttg tggacttttg 420 ctggagtcag tcatgtcaga agaagaagga aatctgtcct acaaagaggc cattgagaag 480 gccggctcct ccatcactcg cttccctctc atccgcatca gaggcgttcc gctcatgtcc 540 cacattgcca acaactggga ctccatctgg gctttccgtc ctgacccgtc agacctcctg 600 atcgccacct atcctaaagc aggcaccacg tggactcagg agatagtcga cctgctcctc 660 cacaacggag atgctgaggc ctgcaaacga gctccgactc ccgtccgcag cccctttctg 720 gagatctact cccctcctcc aattccctca ggactcgatc ttctcaagaa aatggatccc 780 ccgagagtca tcaagactca cctgcccttc cagttggtgc ctcctgggtt ttgggagaac 840 aaatgcaagg ccatatatgt cgcacgcaac gccaaagaca acttggtgag ctactactac 900 tttgatctga tgaataagac tcagcctgag ccaggacctt ttgacggata catcaacaaa 960 ttcatgaaag gagagctgtc atggggctcc tggtatgatc atgtgaagag ctactgggtg 1020 gagaaagaga agaggaacat cctgtacctt ttctatgagg acatgaagga gaatccccgc 1080 cgggaagttt tgcgtatcat gaagtatctg gacttgtccg tctctgatga ggtcatcaac 1140 caaatcgtgg agctgacttc cttcaagagc atgaaggaga accccatggc caactactcc 1200 tgcatcccat cccttgtgtt tgatcagtcc atctcttcat tcatgagaaa aggtgaagta 1260 ggcgactgga aaaatcattt cacgcccgag caggcaaaga tgtttgacga ggattatgag 1320 cagcaaatga aggatgtcaa catacctttc aggagtctca tctgagggat ccatcccgaa 1380 aatgaaaaaa c 1391 <210> 72 <211> 1400 <212> DNA <213> Oryzias javanicus <400> 72 aagcagtggt atcaacgcag agtggccatt acggccgggg gaattgaaag agacaggagc 60 tcggtgaaaa catttttttt ttaaactttg cttcaaagca tctcctactg tcatggcaat 120 gcttcttctg aaacgcttgg cgaaagagca tgaggattac atcaaacaac aagtccatgt 180 gaaaaatcct tatcttgact ccatggagga ggacattctg taccacttca gcctgagtac 240 aaagactcac aacctcccag agatgtttgg agatatcaaa tttgtgtgtg ttggtggaag 300 cgcgaatcga atgaaggctt tcgctcactt catccaccaa gagctaaacg ttcctggaaa 360 cccagacgac atccaagaca tctgtgaggg aacggaccgc tactccatgt acaaagtggg 420 gcctgtgctt tctttaagcc acggcatggg cgtcccatcc atctcaatca tgctgcatga 480 gctcatcaag ctgctgcatc atgctcactg ccaggatgtg gttttgtttc gtctgggaac 540 atctggagga gttgggttaa atccagggac ggtggtgata acagaaaaag cagtggacta 600 ctctttccgc ccccagtttg agcaagtggt tctgggtaag gtcatcacca ggagtacaga 660 gttggacgaa gaggtggcga gtgagcttct gcagtacgcc tctgaactcg agagctttcc 720 aactgttatt ggaaacacca tgtgcaccca tgatttctat gaaggtcagg gccggctgga 780 cggagctctc tgctctttct ctcacgagga gaagctggag tatctgaaga aagcgtatga 840 agctggagtg aggaacatcg agatggaatc caccgtcttt gctgccatgt gccgcgtctg 900 tggcctcaaa gctgctgtgg tctgcgttgc gttactgaac cgctttgaag gagatcagat 960 cacctcttct catgaggttc tggtggagta tcagcagaga cctcaaatcc tggtagctta 1020 ctttatcaag aagcggcttg gacttattcc ctgaagcccc ggatatttaa ataactgtaa 1080 atatgtaaca tttagacatg tatatatcga ttggtgatat ttgaagtaag cacttattta 1140 agtcttaaat gatttattca ataagccaaa tgtattgggt ttgttggatc tttttttttt 1200 tttaaatcct ttgatattta tgtgaggaaa taaaaatatt atgttgagtt gtttctatat 1260 tactgcaaag gttgtaaatt gcacacatga caaatatgaa ataaacttca ttaaatcctg 1320 aataaagttt atttactata gaaaaaaagg aaaaaaaaaa aaaaggccgc ctcggccact 1380 ctgcgttgat accactgctt 1400 <210> 73 <211> 1384 <212> DNA <213> Oryzias javanicus <400> 73 gcagtggtat caacgcagag tggccattac ggccggggat aagggacact aagctgcaga 60 ggttgcaagc tgctcatttt gccctctgtg atcatgtggc tcaccagcct tttactcagc 120 tttgacctga aggcgctctt cttgttcatt ttcctttttg ttttaatagc agattatatc 180 aaacatagga aaccggctaa ttttcctcct ggacctctgg ccctcccttt ctttgggaat 240 tttttgacta tagatggcaa gcatccacac atctatttct taaagatggc tgaaagttac 300 ggtaacgtgt tcagtgtccg gctcggcagt caggctacgg tgtttgtgtc tggctacagg 360 atggtaaaag aggctttgat gacacaggct gagaactttg tggaccggcc attcagtgaa 420 attgctggca ggttttatca aggaaactca aatggtttgt tcttcagcaa tggcgagaaa 480 tggaagaagc agcggcgttt cgctttatct accttacgca cctttggact gggcaaaaac 540 accatggaac agagtatctg tgaggaaatc agacacttgc agcagcagat agaaaacgaa 600 aaggtggacc cttcagccct gcgggtctct tcaacaatgc cgtgtccaac attatctgcc 660 agcttgtgat gggaaaaaga tttgactatg acgacaacaa cttccaggtt atgatgaatt 720 acatctctga ggcagttcgg cttgagggaa gcatctgggg tcttctttat gaagcattcc 780 cgagcctgat gaagcacctg cccgggcctc acaacaaaat attcaggaat tacagcatcg 840 ctcaagactt tcttgatcag gagataaaga tccacaaaca ggacctagat cccaataatc 900 ccagagacta cattgactct ttcatcattg aaatggagaa acatcaagac tcaagcctgg 960 gtttcaatga ggccaatctg gcctactgct ctctggatct cttcgtggct ggaacagaaa 1020 caacctccac cactctgatg tgggccttaa tttatctcat caaacaccca gacgtccaag 1080 tgaaagtcca gcaggagatc gacagagtga ttggtcagaa ccgtctgccc tctatggctg 1140 acagacccaa cctgccgtac actgatgccg tcattcatga aatacagaga attggtaata 1200 ttgtacctct gaatggactt cggattgctg ctaaggacac gactttgggt ggttacttca 1260 taccaaaggg gacttctttg atgcccatgc tgacttctgt cttgtttgat aagaatgaat 1320 gggaaactcc agacaccttc aacccgggac actttctaga tgctgatgga aagtttgtga 1380 agaa 1384 <210> 74 <211> 1380 <212> DNA <213> Oryzias javanicus <400> 74 agatgctctt gggtcggagg caggaggtgt gcgacagtct gaagctgccc ctggaggagg 60 tggagctcag catgggcatg tccaccgact acgaacacgc gatcgaggtg ggcgccacca 120 acgtgcgcgt cggcagcatc atcttcggca acagggagta tcccaacagc gcggccaaca 180 ctccgaaccc cagtccgagt ccgagtcccg cccacagccc cgagaagaca tccaagatgg 240 tgtgtgaaga agctgccaag aagatgcatc atctcaccgt ctaagcacac taaagctgag 300 ctggctctgc gtcgagccgc agatcccggg gaacttttcg gaaacgtaac tacacatggg 360 ctcgatgcaa actgctacaa gttttgagga ttttcagcta ctctcctctt tttggtatct 420 gttgggatta gtgatgtaat cctgagattc cttcaggccc ttcaactaaa ttatcctctt 480 taagtaaata aaatgtgaaa tttcactctg gagttcagct gggacattct caaagattgt 540 agaaaaaaat ctcagcctga taactgctag gtctgctttg gcttcagcaa aaaaactttt 600 actgccattt agtgttcaga ggtgttactg caccttcaaa gagacccata aacaaagcgc 660 cggaagagct tcaaaacctt tgaccttagg aaaacttttg gagaaaaata acgactgatt 720 tacgttaggt ttgcaggttt tattgaattt aactgggatt aacttagcct ttagcctttt 780 taagcttttt tttgtttttt ggctcataga ggcgttacat ttctacgact cccttcacaa 840 taaactacat gactgaactc tgtaacagac gtctggataa tttactttgt tgttttctaa 900 ctcttcaacc taacttgtga cagtgcagaa ttgtgcgtca tgaactgcac acaggacagt 960 aacattttta ttgtacagct gaaacaaaga cttgtcttaa taaaccatct gtccctttat 1020 aatgacactc agtattgtgt gtttgatatg gtttttcgta tgatgtgcca aacgtgtcag 1080 atctttattc ttgatatgaa cagatgcgtg tgttttgtgt tgtttgtgcg tctgtgttgt 1140 gctgtagtgt gttgttgggg gtgtgacaga gtaaacctat gcaacatgtt ggtcttaaac 1200 atgcagcctt ttgttttgtt tttaattttt tttggtccgt taagtttgtg ggagggacta 1260 aagggtcaga cgtgtgcttg ctgttttagg cgttttatca ttgtttggtt tggactttgg 1320 ttctgattgg agccaaaacc aagcaataaa ttttactgtt caaaacaaaa aaaaaaaaaa 1380 1380 <210> 75 <211> 1373 <212> DNA <213> Oryzias javanicus <400> 75 cagccctccg ccgactacct ggactttcgg aaccgcctga tccagaactc ggtatgcctg 60 gagaactgct ccctgcagga gcgctccctg acggggacgg tcaaagtcag aaacgttggg 120 ttcgagaagc tggtgcaggt gcgcatcacc ttcgactcgt gggccagcca caccgacgtg 180 gactgcacct tcctgaacaa cgtctacaac tgccaggaca gtgacgcctt cgcgttcgtg 240 gtggagctgc ccgcctacgt gccgccgcag aaccgggtcg agttctgcat ccgcttcacc 300 gtccagggcc agacgtactg ggacaataac gacggcaaga actacaccct gaagcacaac 360 ggctggagcg gcgacgacgg ggcctccgag cccaagcggc ttccggagca caagaacgcg 420 gacgggaagg cgctggacct ggggttcgac cagttcggca gtccgcgcat gtccagcgga 480 cttttccccg gctggcagag ttggggtcac ttcgacaaca ccgtgcctta ctggtgaacg 540 gctctagcag aagtagtaca aaaagaaact gacctacttt gggcccggta aatgattgac 600 ccgcggctac aggaggaggg accttttttt tttttttttt tttttagtta aaatagtaaa 660 tgtgccttct tatcacgtct gcccactaaa atacagactg agttgaatat gcactgactg 720 cgctcaatgt ggcgtctgta tacgaggaag gaaaaaggag ctgattatgt ccttcatatt 780 gaagggaaag ctagggggtg catgaccgta gaatgaaatt ttaggttaat ttctaataaa 840 atatgtaaaa aacagaaaaa aaaatgcaca ctaaaccttt gcaccctcct gtattcaaag 900 tgatttctaa aatgggagtc atgcagccct tgttttccct ccgtgtaaat tgcacatcgg 960 ttcaagttgt aattctgaga aggaagctgc tatattgacg tttgagagga tctgcatgtg 1020 attggttgct tacaacacga gagatgtttg attcattgtt ctggtaagtg aagaaaagag 1080 atggtgtgga gatcgaatgt ggtcggttgc ttgtgttcac aagtgcaatt cttaatgttg 1140 agtgtacagg atgagtggct ggaatccaga tttgtgtttt tttgaaactt ttagtcactg 1200 tgaagaaaag gtctagaccc cggcattttg tgtctcactt gaaggtgtgt gttgctgacg 1260 cgcgccatga ttgtaatgta tttacttttt gaaataaatt tatatatatt tgtgtaaaag 1320 aaaaaaaaaa aaaaaaaagg ccgcctcgcc actctgcgtt gataccactg ctt 1373 <210> 76 <211> 1372 <212> DNA <213> Oryzias javanicus <400> 76 tttatttctc ctaaaagaaa gtttgacttt tgatctccag cgatgtttcc agaggcaaat 60 aaaggctaca gctacgacga ctgcaaagcc actgccgatt ggctgctggc acagacggac 120 atcaagccca gagttggtat tgtttgtggg tcggggctcg gagggctggc cgacctgtta 180 aaggaccagg tggccttcaa ctacaaggat atccccaact ttcctcagag tacagtgcac 240 gggcacgcag gacgcctggt gtttggcacc ctgaagggaa gggcgtgcgt ttgcatgcag 300 ggtcgcttcc acctctacga gggctatccc gtccagagga tcactctgcc catacgcatc 360 tttaagctgc tcggtgttga gacggtgata ctgaccaacg ccgctggggg gctgaacgaa 420 gacttcaagg tgggggacat catggtgatc aaagaccaca tcaacctgcc cggctttgct 480 gggaacaacc ctctggtcgg acccaacgat gagagatttg gcgtccgctt cccttgcatg 540 tcagacgcgt acgaccgaga gctgcagcag ctgggcatgg acgtgggtca ggagctggga 600 tatggagatt tcctgaagga gggcgtctac tgtgcgctcg gcggcccctc gtttgaaacg 660 attgccgagt gccgcatgct gcacaaactg ggtgtagatg cagtcggcat gagcacagtc 720 cacgaggtgg tggtcgcccg ccactgcggc atgcgcgtct tcgccctctc gctaatcacc 780 aaccaggcag tgatggacta cgacagcgag gagaaggcca accacgagga ggtccttcaa 840 gccggcaagc agcgaggcct gcagatggag cacctggttt ccaccatggt gacccggatc 900 gagcacaaca acaacagcaa ctacatctga gatgaatctc tacatcgttc tctgtgcagg 960 gacaaggaca ttgactttgt cgtggcttat ctttactgtc aaaccaaaga aaatctgtct 1020 ttacgtgcaa gtttgagtct caaaaactgt taaatttcta cttccctcct ctgtgctgta 1080 taggacacac attcctttaa ttggttttct gacagaaaaa aaagcttttt ttgtgtttta 1140 gcagaaacat ttaaaaaaac aaacttgttc tgctatgatc catcccagat gacagatatg 1200 ttttgtgtat tattattcta acttatgatc ctcttttaaa agcctatgca atttaactta 1260 acaattatca taaatcgact gtaaaaatgt aatattgctt gtgtacaccg agtgtattag 1320 tgcttgtttt tttaattatg actgttgtta ctaaaagtgt tatttattac ta 1372 <210> 77 <211> 1333 <212> DNA <213> Oryzias javanicus <400> 77 aagcagtggt atcaacgcag agtggccatt acggccgggg gcttggcagc tggtgagagc 60 aaggacggtg gtgtcgacgc tagaagtttc tttgcagaca ataaccatcc aattcggaat 120 ctaaaacctc ggaataagga aactggacac gtttgaattc gcttaaatta ctcttcagca 180 gctgttgaat actgcaacca tgccagaagt ctttgcaccc gcagacatgg gcagctcacc 240 tccatccccc gtggacagca gtccgaggag actgtcctgg ggcaaactgg tccacaggtt 300 gacagatttc agcacaaaca gcagcagtat cacgtcaggg tccaacaatg gcagcaggag 360 tgacctctcg gaatctgggt ccgatacctc cagtgacctg tcaccgtaca atgatgacct 420 cttcttcgat ccgatggagg aaaccatcct gaaagaagtg gtggacctca tcgcatccag 480 ccttagagaa gccaaagact cggactgtgc tctgaggtgc gccaagctcc tcattcccga 540 gaaactgctg gagcacatcg gacgggagct ccttcatctg gctgccagcg agccctgcgg 600 attgaggggg gctctcattg acctttgtgt ggagcaagga gatgtgtgtg agagcatggc 660 tcagctatcg gtggacccct gcctcgtccc cacttttcag ctgactttgg tgttgaggct 720 tgagtccggt ggcttgtggc caaaaattca aggacttttt agctccagat ctacttccac 780 tccagcagtc cgacaagcac ttaaactcag cactggtttc cgcgtgatca aaaagaaact 840 gtactgttct gaagacctgc tcattgagga atgttaagaa atgaaagact cgtttttttt 900 ttaatataat gcgagcttac aatgaaagct caaagaaggg ccttttaaga ttatgcctac 960 agaagtataa agaaggactt tgttctgatg tagcctttgg ttcctgctgt aagtttctgg 1020 tacttggatg tcttcatgca gcacttgctc aaaacttaag tttaaaaaat gtaaccatat 1080 aatatctggt acatctgcat ttgaaactga atttgaattt taaatgcacc gacgtttcta 1140 ctgaaacatt gaaaaaggca gctagctgta ttgtgttacg cattgaagac aactgaattg 1200 tacggcaact catgacatgt actccaattc ctcagtttgg gaacatttaa gctaaagctt 1260 gcacatgtgt aagcctccac tttgatatca cgtctaagtt tttttttttt ttttgttttt 1320 ttttttcttt tac 1333 <210> 78 <211> 1327 <212> DNA <213> Oryzias javanicus <400> 78 tccaggtgca ctctgtcgcc cggcagctgg cccagttcac ctccatcacc acctgcttgg 60 ctgtcggggg tttggacctg aagtctcaag aagcagcatt gagggcgggg ccagatgtcc 120 tgatagcaac tcctggtcga ctcattgatc accttcacaa cacgccaaac tttgaactga 180 gtcacattga gatcctgata ctggacgagg ctgacaggat gctggacgag tactttgaag 240 aacagatgaa ggagatcatc cgcctgtgct cctataacag acagaccatg ctgttctctg 300 ccaccatgac agaggaggtg aaagatcttg ccgccgtgtc gttgaagcag ccggtcagga 360 tttttgtgaa cagcaacaca gacgtggcgc cgttcctgcg gcaggagttt atccggatcc 420 gaccgcacag agaaggagac cgagaggccg tcgtggctgc tctcctgacc cggaccttcc 480 aggaccacgt catgttgttc acacagacca ggaaacaggc gcacagactg cacatcctgt 540 taggcttgat gggcctgaaa gtcggagaat tgcacggaga acttagccaa aatcagagac 600 tggaaaacct gaggcgtttc aaagatgaac agattgacat cttggtggcc acagacgtag 660 cagctcgagg tctggacatc gatggagtga agacggtcat aaacttcacc atgccatcca 720 ccgtcaacac tacgtccacc gcgtaggccg cacggcgagg gccggacgct ccggtcgctc 780 cgtgtctttg gttggcgagt cagagcggaa gattctgaag gaagtggtga agtcagctaa 840 aaacactgtg aaggctcgag tcctgccgcc agatgttgtc ctgaagttca gagatctgat 900 ctgcaaactg gagaaagacg ttgaggctgt gatgagactg gaaaaggaag aaagagagct 960 ggctgcttct gaagctaagc tcagtgtggc acagaagcgt ctggatggct ccgcctcatc 1020 ctccgaatct cagcgagttt ggtttcagac tcagcaagag aggaagcaga accgggtgtc 1080 gaaggctctg caggagttcg atttcgccct gagagggaag aagaagagag agaagtttgt 1140 gaagaatgcc aagaagaaag aactttcttc tgaggagcgc gctcagttcg agatcctgaa 1200 ggcgcagatg tttgctgaac gagctgcaaa gagggagagg aggccgaaga gggccagagc 1260 aatggccgaa gaggaggctc cagtaaaaga taaagcagcc aatcagaaga caggaggagg 1320 aggagga 1327 <210> 79 <211> 1311 <212> DNA <213> Oryzias javanicus <400> 79 aaggtttggt gtcacacagt gacttagacg atcgagcaat tgaggctcta aaagaattca 60 acgaggaagg tgctctccaa gtcctttcac aattcaagga cagcgacctc tcacatgttc 120 agaataaaag tgcctttctt tgtggtgtga tgaagacgta cagacaaaga gagaaacagg 180 ggaccaaagt gtcagacaca agtaaaggac ccgatgaagc caaaatcaaa gctttgctgg 240 agagaactgg ttacacgctt gatgtgacaa ccggacagag gaagtatggg ggtcctccac 300 cagagtctgc ccactcaggg ggtcagccca ctatcggtac agagatattt gtcgggaaaa 360 tccccagaga cctctttgag gacgagctgg ttccgctgtt cgagagggcc gggcccatct 420 gggacctgcg cctgatgatg gatcccctca gtggcctgaa cagaggctat gcctttgtca 480 ctttctgcac taaagaagcc gcgcagcagg ctgtcaaatt gtgcaacaac agtgaaatcc 540 gaccgggtaa gcacatcggc gtgtgcattt ctgtggccaa taacagactg tttgttggat 600 ccatccccaa gagcaaaaca aaagagcaga ttattgaaga gcttttcaaa ggttacagag 660 ggtctaaatg atgtcatatt gtatcaccag ccggacgaca agaagaagaa ccgtggtttt 720 tgctttctag agtatgaaga ccacaagacg gcggctcagg ctcgccgccg actgatgagc 780 ggaaaggtga aggtgtgggg aaatgtggtc accgtggagt gggcggatcc catcgaggac 840 ccggatccag aggtcatggc taaggtcaag gtgctgtttg tgaggaactt ggcaagtgcc 900 gttacagagg agctgctgga aaagaccttc agtcagtttg gcaaactaga aagagtgaaa 960 aaaactgaaa gactacgcct tcatccactt tgaggaaaga gacagtgctg tgaaggcttt 1020 aagtgacctc aacggtaaag acttagaggg agagcacatt gagatcgtct tcgccaaacc 1080 tcctgaccag aagaggaaag aacgcaaagc ccagagacaa gctgccaaaa cgcaaatgta 1140 tgatgaatac tattactatg ggcccccaca catgccacca cccacaagag gccgaggtag 1200 aggtgggcgg ggcggttatt cttacccaca cgatttttac ggctatgaag actattacga 1260 tttctacggt tatgattacc acaactaccg gggggttatg atgacccata c 1311 <210> 80 <211> 1251 <212> DNA <213> Oryzias javanicus <400> 80 gcagaagacc aacaatgaga gctggggctt cagcatcgtc ggtggctatg aggagagcca 60 caatcagcag caccagccct tcttcattaa aaccatcgtg cctgggacgc ctgctcactt 120 cgatgggcgt cttaagtgtg gagatgagat agtggcggtg aatggagcca ccactgtggg 180 aatgaaaaac aactctctga tccccatgct gaagctgcag aagaacaaag tcacactgac 240 tgtggtgtcg tggccgggca cgctggtgta gcaaacctcc cgtttgttca gtcctcatct 300 caattttaca tgaccaaaaa gaggtttctc taatctgagc tggaaccctg cgtacttcac 360 tgtttgtctg ttcttgtctt gatgtagtgg agtgtgtgtt cacgagaact acaaactgtt 420 caaaaggagt ggatttttaa ttaacaaatg gcagttaatc actggttaaa tacagaagga 480 tttcttttgt ccgattctgt tccgagcagt tgtgttaaga tagtttgatc ataatgtaca 540 gaaataaaat atatagctga ttaatgacaa gtttgtacaa caagaaattg ctgcagacac 600 tagaacaaat aaatagatgc acttttaaaa agtgatatct cagaggaaaa atcaggctag 660 ttgaatcaca gtcgagcttt gacgagttat aatacttgtg ttgatgggag gcttctgttc 720 tgttctttta tttttagaaa tgtgaggcct tggttattca gaccatcaaa atgacaagaa 780 gtcattttgg cgtctggctg ttggtgtcta tcctcattga gcgttacatc attcaaagtg 840 gggaagtatg atgtatggtt aatgtgaagt gatccaaaga aattattctt tgtaattggt 900 tttaattaat actgcttgta atcctttgga ggaacattta ggaggttcag atgcttcaag 960 catttggcat cattttgcaa aagtgctttg aattgtcttt cagaaatcta aatgtctttt 1020 tctggatgat tcgctggttt tccgttggta ctgaaggaca aaccagaatg tatcgttgcc 1080 ttaaagagcc tttgtaccaa acagttttct cctcataatt gtggccttgc ttgcatcttg 1140 attgatggaa gactttttgc acaattcagt gttcgtgtca gatgcagcac gcagtgtgtg 1200 atttaatcca gccactgttt cattgtcaat aaattcacat caaaaataac c 1251 <210> 81 <211> 2040 <212> DNA <213> Oryzias javanicus <400> 81 aagcagtggt atcaacgcag agtggccatt acggccgggg gacgaagttg cgaaactccc 60 gtgtaggagg gagctgctct gcaagcctgc tgaaagagga ctttaaaaac gcaaaataac 120 cttaaaaaca gaaaccgtaa acgccaatcc tccgaaacct acatttactg gaatattttt 180 ttgtaaaact gataatatat cctatgtaaa gaaagtattt atactttatt cctatttgca 240 ctaaccaacg gtacttcaga actactgaga atctttattt tttacgaaaa aaagaaatat 300 taaacaccct gtggagggac accactacat tacaaaacca gcactttttt gattttccaa 360 cctgtttcat ccacgtcccg gttgctttcg ccgccctgcc tggagcacgt ctgtgttgcc 420 aaacacggat aaacaaagca gacccggtgg acacgttcaa ggtcagacga agctaatctt 480 cacacatctg gtacacttca gcagtccgct atgcagctcg aaatccaagt agctctcaac 540 ttcatcatct cgtacctgta caataagctg ccccggaggc gggtcaacat cttcggcgag 600 gagcttgaga ggcagctgaa gcagaaatat gaaggacact ggtacccaga caagccatac 660 aagggctcag gattccgatg catccacgtg ggggagaagg tagaccctgt ggtggagaaa 720 gcagccaaag agagtgggct agagatcgag gatgttcgca ataacctgcc ccaggacctc 780 agcgtgtgga ttgaccccta tgaggtgtcc taccagattg gagagaaggg gcccatcaaa 840 gtattgtatg tcgatgacag caacgaaagt ggagccaaca atggaggact cgatctggac 900 aaggagatca agaacagttt caatccagaa gcgcaggtct tcatgcccat cagtgaacct 960 gcgaacgggg cctcgccggg ctccagctct ccatctcccc cgtttggcca ctcggcggcg 1020 gtcagcccca ccttcatgcc ccgctccacc cagcctttaa ccttcactac agccactttc 1080 gcagctacca agttcggctc cactaagatg aagagcagtg gacgcagcag cagcaacaac 1140 aacaacaacg gcggcggcgg cagcagcgct gggaacaaag cggcccgtac ctctcccacc 1200 aacctgggcc tgaatgtgaa cagtctcctc aaacagaaag ccatctccac ctccatgcac 1260 tcactgtacg ggctgggtct cggcccgcag cagcacccaa agccctccgc cttgtccccg 1320 aatgccaagg agttcgtgtt ccctcccctg cagggccagg gtagccagag tgctctgttc 1380 ccaggagaca gctcgctcag cctcagcccg ctgcagtaca gcaatgcctt cgatatgttt 1440 gcggcctacg gtggccttaa cgacaagtcc ctcatggatg gcttgaattt cagcttaagc 1500 aacatgcagt attctaacca gcaattccag ccagtcatgg ccaactagta cgcgttaaag 1560 tactacttaa gctacttcat gcagaaatga ccagagataa tgtgatgggg ggaagcaaaa 1620 cagatgcaca ttttgaaaaa aagaaaaaca actttaaaaa aaagtgtaaa cacaaaaaaa 1680 aaccagaatg tcaaagtaaa agataaaaaa aagacttgta aacctgtaag atctcagttt 1740 cgagtcagag catgagcccg agggagaatt tctacgcccc cttgagttat actgtttcat 1800 tttattttta ttttctttct ttctttaaac aatgaagctt gtagtacaag atgtccaagc 1860 ttggttacct aaacttacga atgcatcgtt gtcatttctt ttgccaacca agcacaaaat 1920 atttttttta tgtaactgtt ttaagatata tatattgaaa aaaaaagagg acaaaaaaga 1980 agaaaaaaag agagacatca tcacaagtca tggcctcttt cagtatttaa aaacataact 2040 2040 <210> 82 <211> 1245 <212> DNA <213> Oryzias javanicus <400> 82 aagcagtggt atcaacgcag agtgccatta cggccgggta cacgaaaggg gaacaaaatt 60 cgctttgcaa atcactcggt taatcctaac tgctacgcta aagtggtgat ggtgaacgga 120 gatcaccgca ttgggatttt tgccaaacga gcaatcctgc aaggagaaga gctcttcttt 180 gactacagat atagccaagc tgatgccctc aagtatgttg gaatagagag ggaggtagac 240 atgacttagc ggcctccata accggtgttt gtgattttaa tcacagcagt tcaccgcact 300 tcctaaaaaa agaaatttgc aggttttgct gctcagcaaa cactacacca tctccatctt 360 ttatctgccc aaacctgcaa gattcccacc gtacatccat aaaagtattt taactggaaa 420 tattatgaat tagtaccgct tcctgcactt aagaatttca catttaattc cattctctta 480 aagagaagat gctacattac ccattacatc aactattgat ttttgttgcc gtactaatca 540 actggttttt gttacacgtc tcagcacatg tatgcaagct ctacagcaga acgacacgca 600 tgagcggaca aacctttcat taaactcttc gctgctgtca atattgtatt cggtgaggtt 660 acgctttgac tgtttgaccg catgatgtgt ttttcagcag ttggcttcac caccacatct 720 ttgtggtaaa aaaaaaataa taataataat aagctatttt gtgtctgtat cgttgtgctg 780 caaaagttaa aaagactaaa caaaaaggca acctggcaag aaaccgactg actgaatgta 840 acgtgtagat gactgaatag atctcaaccc tttttttttt gtgtccaatt ataggtactt 900 aaaacgttgc acattagtgc aataactaac atgtttacat gatcgatcct gtttggcaaa 960 aaaggtccaa tgtaaatgtc ttcctttcaa acgcacaaaa gtgccaaaac attcctcccc 1020 cccaaaaaag cactataaaa atgttgaaca ttttattact ttaaaaacaa aaatgattgt 1080 ttttcggcca aaaattaaat tccaccccct taacacgtga atgtaaaatg tcatgaattc 1140 agattttgaa agccaaattt caatgagatc attctcaggc gtgctgaaga aaatggagtt 1200 taatgctgtg tacagtgtat gcctagtaaa ataaaaacct aactt 1245 <210> 83 <211> 1242 <212> DNA <213> Oryzias javanicus <400> 83 agcgacctca gcatgctcag catcctggac cacatggacg aggaggtgga cgggttcgtg 60 tcacctgtgg atgagctgaa gaacacaaca gacatgaggc tgtccaacct gcactcagct 120 accatgcagg aactcgtcga gcagcttcag gaggcaagag aggagaaaaa gaggatccgc 180 aagaacctca aagagtttga ggaccagttc tttctgcaaa acggcagaac tgctcaaaag 240 gaggatcgct cgccacttgc agtcgagtac catgaataca aacacatcaa agccaaactg 300 cggctgctgg aagttctcat cagcaaaaga gatgctacta agttcatctg aaaaaagaca 360 aaagactcta aaaagactgg tgctcagtgt ctagcgatac ggtgaaacac atctttctta 420 aggagagaca gcccttcatg tctacccacc tgttactgcc cactagactt cacctgaagt 480 cctccgtcgc cttcaaatgg atgttccttc aaagccagac gcgcacaatt aatcagtttt 540 tttattaaat gaatgattaa tttattccta acatcttgaa agtaacaaat tgtatttttt 600 tctcctgttt taactgtaga aatctctaaa gaaaaagaaa acataaataa tttaaagtat 660 agttaaaaag ttattgaaga attttgtgct gaagttgtgt atttatgtgt attttttcta 720 agggagacat tacttatgtg tgtcatcttc accgccttca tttaacaaac agctttctgt 780 gcttcgtcct gaccgacgca atagcctcct gtctcgccac gaccccaaag gcatgatcag 840 aagttcagtg aaaggattgc ctgtgagcac tttggccccg tttgttccaa acacatttcc 900 atctttactt catgtccaat aagctattag gtctctggtt tgacgcgatg gtagaggtgg 960 ggggtgtaaa atagctgcta cacgtgacgc cacgcttgac cggtgcatct gtcatcgcct 1020 tcagagttcg attgctcgtc tgtaaatact gatcacctgt tatgtttaca tttctgtgag 1080 cgaatactcg acttcttttc ttttctccaa agtggatgat tatcagtgtg aatttttttt 1140 cacttcatgt aaacactggc caggccgaat gaaacctcga gtgtgtacat tttagtacat 1200 aaattggatt ttgtaaataa taaatgaaaa tcctattttt ac 1242 <210> 84 <211> 1234 <212> DNA <213> Oryzias javanicus <400> 84 atgaactacc tggtgcacgc cgtcatgtac tcgtactacg ccctgcgggc ggccggcttt 60 aaggtgtcgc gtaagttcgc catgttcatc acgctgaccc agatcaccca gatgctgatg 120 ggctgcgtgg tcaactacct ggtgtactcg tggatgcagc agggccagga gtgtccgtcc 180 cacatgcaga acattgtgtg gtcctccctc atgtacctca gctactttgt gctcttcgtc 240 cagttcttct tcgaagccta tgtcggaaag tcaaagtcgt ccgccgccag cggcagcaag 300 aagagcgagt agaagccgac cagagtggcg gcggcggcgg cggcgaggcg gaagctggga 360 atcgaagaac gagcagtgaa ggagggggga ggggggttgt gcttgagcat aacgactaat 420 gtgcagatct aaaagaaaaa gaggaactca ctgatggggg gcagggcagc accgtgatca 480 aatccatcag aagctccgcc ccctccccgt ttcaacttag atttagtact ttatgaaacc 540 taacatgtaa aaaagaaaaa aaaatgggat caaatccttc acatctgcca gaagctactt 600 tatttattat ttaccaaata gtaggtacat atgaaggtgg acgtgtgacc tttgaccggt 660 cccgctctct gtctgtgctc gttttgtttg ggcggggctg atcaataacg tgcatatcga 720 gacaaagtaa acgtgtttaa caactgagct aatgagaggt gtgagcgacg gaatgaagtc 780 gggtggattg actgacggac gagcgcgccg cgcctgagcg tgactggaaa cacgccgccc 840 cgcttgtctt gactgcactg agatatacga gctgccactg attcccaaac acttgtgtgt 900 cttaaaggaa cagcagtccg ttggacctga aggtttaaat ggaggacaaa catttttatg 960 tctagcaaag gaaaaaaaaa caacaaaaat tgtcaaaatc tgctgtattg agaaaaatct 1020 gatgtatccg tgatggtgtc ttgtgctttt tgtgcatttt cactgtatca atgtcagaaa 1080 acaacagaga acctgggtgt atgcagaact gtgacatgcc tgtggtgttc ttttgctgcc 1140 atcctgtcat taaaatgcat aaacggtctc ttggtgctga aggtcaaaaa cacaaataaa 1200 gggtgtacag ccacgctggc agttgtcgga gtag 1234 <210> 85 <211> 1223 <212> DNA <213> Oryzias javanicus <400> 85 aagcagtggt atcaacgcag agtggccatt acggccgggg gcgtcttttc cacatgtttg 60 tagctcgcag tggtgcagac gatttgttag cgcgagacat ttcgttggtt tataaatcgt 120 ctttgtagtt tcggcatcat cttgcgcgct tagcgtttgt ttatcagtgt gggacaaatc 180 attccgatta aagaagaaac agaatacgtt taaaggaagt gaattagcta gctagctagc 240 ccagcagcag tcagaggagc atggcagcaa cgctgggact agtggctgga agctacgagc 300 agatcatcgt tggttaccga gtaaaaactg gtgaaaaaga gtggaccgct gaggctgact 360 tcactcatca cactcacaca gcttccattt cagctgtcgc agccagccag aggtttgtcg 420 tcacaggaag caaagatgag accattcagt tgtatgacat gaagaagcga accgagcacg 480 gggctttgct gcatcacgat ggcaccatca cttgccttca gttttatggg gattctcatt 540 tactgagcgg aggagaggac ggactgatgt gtgtgtggag cacaaagaag tgggagtgtc 600 tgaagtccat taaagctcac aaaggtcacg tcacatcatt atctgtccat ccttcaggaa 660 aacttgctct ctcagttgga acagacaaga ctctaagaac ttggaatctt gttaatggaa 720 ggtcagcttt catcaaaaac atcaaacaaa acgcacacat tgtcagatgg tctcctgatg 780 gggacaagta tgtggttgtg atcaatgata aagtcgacat ctataagctg gagacggcct 840 ccgtcacggg aacagtcaca agccccaaaa ggatctcttc tgtcaagttc ctaaataact 900 ccatcctggc cgtcgctgga gatgacgagt cggttcggtt atgtgacgtc caaaaagccg 960 agtgggtgtg tgagttcaag gctcatgaaa ccagagtaaa agcagttgat agtttctcta 1020 tggaggatta ttgtgttttg gtgacggctt caaacgatgg cttcatcaaa atgtggaaaa 1080 tccatctgaa agagacgctg gagtctccga ctcttctggg ggaagtgaac acatcagcca 1140 gactgacctg ccttgctgtg tggatcccat cctcagtaca gcaaacggat gagaaaccag 1200 catctgaagc aaccacatct gaa 1223 <210> 86 <211> 1198 <212> DNA <213> Oryzias javanicus <400> 86 aagcagtggt atcaacgcag agtggccatt acggccgggg aacgacggaa gacgtctccc 60 ccgtgatacg gattactgtg aatttctcaa aatttaaacc ccttttcctt cctcttttgt 120 gtcaagacag catcctttcg ataaaatatt tgttttatta actatttcaa aagccaaagc 180 atgtccaccc cggctagaag aagacttatg agggatttta aacggctaca agaagacccc 240 ccagctggtg tcagcggagc cccatctgaa aataacatca tggtttggaa tgctgtcata 300 tttggccctg aaggaacacc atttgaagat ggtacattta aactcattgt agaattcaca 360 gaagaatacc ccaacaaacc ccccacagta cgatttgtgt caaagatgtt tcatccaaat 420 gtctatgcag acgggagtat atgtctagac atcttacaga accgctggag ccccacgtac 480 gacgtgtcat ctattcttac atccatccag tccctgcttg acgagccgaa ccccaacagt 540 ccagccaaca gtcaggcggc gcagctgtac caggaaaaca agcgggagta tgagaagcgc 600 gtgtccgcta tcgtagaaca aagctggagg gacagttgac ctgacaatcc tgctagctgc 660 tatattaagc tgtgcgagct ggaagtttta gtggactctc ttgttacccc ctcacctttt 720 ttttaatttt ttattttaag ctttttatgc actttacctt aatcttccac tcagttttct 780 tttgtaacca cttttttttt taaatatttc accctcttct aatccttcag ggggaaatgt 840 gttgaaactt gccttggtat tttgtcagaa ctgatttgag gattacaaaa actatttgct 900 tataacgatt cataaggggg cgtcaatcaa gtggtgggtc atttctgttg atcggttttt 960 ggttctgaag gaagtgagga tgatgaggag tcttggaatc aagccccaca actgaatcgg 1020 gcatctttct gctgtgtctt tgctgtgaac tgttacatac atgcatgatt aaatgttctc 1080 ctgacccgtt cacttctgca tacaacagaa acctgcaagt gaaattatgt acagattttg 1140 cactggttgt cccccatgta agtcttttcc agaaattgta aataaacaga caaaatta 1198 <210> 87 <211> 1196 <212> DNA <213> Oryzias javanicus <400> 87 gctaccccca cctttacctc cacaccttta tccacctaca ccgcctcctc agtacttgac 60 agcgactctt cttctcccaa tcaccaggca gaccctggta gccatggcaa ctcggaggtc 120 agagaagcta agcagctgag ccccactgcc tcaatacagg aaacgcagaa gtggctgctg 180 aaaaaccgct tcagctccta cactcggctc ttctctcact tctcaggttc agatttgtta 240 aagttaaccc gggacgacct ggtccagatc tgtggtccag cagatggaat ccgactattc 300 aatgcactca aatccaggtc agtgcgtccc aggttgactg tgtacgtctg cagagagtcc 360 tctcagcaga gccccctgct ggagagacac tgcaccagcg aaaatggaga agacggcgtc 420 tcccctcgtt tacacgtgta ccacgctctg tacttagagg aactcacggc tgcagaactc 480 atcaggaaga tggcgtgtgt gtgcagcatt ccactgggaa agatcaacca ggtctacaga 540 cagggtccta caggcattca catcctgctg agtgaccaga tggtttacaa cttgcctgac 600 gagagctgtt ttttaatcag cactgttaaa gatgaattgg gcgacggact tcatctaatc 660 ctgaagtagt gaggaggaca gatggcatca gtaatactcc aaccctctgt tttggagcag 720 acgcctccct ctgcacctcc ccctccgcct gcctctcctt tttttgtttt cctcctcctt 780 tccctccctc cctgtctctc ttcacttgat gcacagactg agttgaagcc atgtaaatgt 840 tagaatctga catgggtgtg tccactgttt catattgaaa acattattaa tgaaggagat 900 aagttaaaaa gagagagaga ccagggaggg tgttcagtaa aagaggggag aatgaatttt 960 atgtttttgt ttttatatgg tttgtgtgga gagtaagagt ggaaaggctc caaacgagac 1020 gcggcgtttg atgagatgag ttgttgccca tcctcttgca aacacgcaca accagcacta 1080 ggccagtatt taaagaacct gtaacgcatg tggtctccta atagcttaca gaagacttcc 1140 gcttattaaa cattctcgat gggataaacg agcagccgag ttgaatttaa aaaaag 1196 <210> 88 <211> 1168 <212> DNA <213> Oryzias javanicus <400> 88 agcagtggta tcaacgcaga gtggccatta cggccggggc tctctgatct ccgacatgtc 60 gtctcctcaa agccccgccc actctgagcc cgcgcaggaa gacgagaaca agctttgctc 120 aacgggaact ctgatccacc ccgggacccc acagacttct ccaagcagga gtcacccgcg 180 ttagaggcga cccaccaaag cactgaagag ccctcccggg tctccggaga gaaatcctcg 240 tctgagcagc aaaccgtggc tgtggaaaag tgtggcgctc agacgaccaa cggcatatcg 300 gcgctttcca gtaccagagt gacacggaac cagaagagga agagggagga aacgatgccg 360 caaaaatcca aaaagacaaa cctcgtaata agccatgaca gtgagaccga tatttctctg 420 gatatgggcg tctgcagttc tccacaacac gaagtgtcgt tcaaagcagc aactccaccc 480 aaaagactgg gcaggagctc cccgtccaca ccaccaccca agaagaacaa ggtcaacgtg 540 gcgactcagt gcgacccctg cgaggtcatc gtcctctccg actcggagtg atgccagcgt 600 tccaccggcg ctccatagac attgttttcc ggagagttgc ggttgatgaa gatgacgggg 660 atttcttcat ggaggcacta acatttgcag ctttcagact gatcactaaa agtcactgtg 720 tggtgctggc tctagtcaga ctggtcagaa tgcgtggctg tcatgagtca gcacgttaat 780 gatttgttaa tatgcagctc acatgttctc tgatcgagct ctgttctctg attgttgtgt 840 attataggat cttctcaatc gatttgtttt atttgctgtt gttgagtgtg agtctttgga 900 tggttggtgc tgctgtcaga acagacggcc gggacaagcg ctcgacgcta gagatcttta 960 gaacttttag aatagataaa gcacaaagta aaaaaaccac ttaggaaaaa gaaaaatgca 1020 atttaactgc agttgataga aaatcagtga ccaagcttcc aaagattaaa agaaaaattt 1080 taggaaataa ttcaccacat tatgaagaat tttctgacat ttttcttttg ttcaatgatt 1140 ggatgaggtg tttatcatcg tgacactg 1168 <210> 89 <211> 1160 <212> DNA <213> Oryzias javanicus <400> 89 aagcagtggt atcaacgcag agtggccatt acggccgggg ttttcggttt tttcctttta 60 agtctaggaa gaaagtcagg ctatttgact tgaatcaagt gagaagaaga aagtgagtcg 120 ggatgactgc cctcctcctg cccagtctcc tgctggctgc tccgatcctc ctggtggcgt 180 ccggccctct cctggctcca ccaacaacac ggtgcctctg gttctgtggc acgggatggg 240 cgacagctgc tgcaacccgc tcagcatggg tgccataaag aagatgatcg agcaggagat 300 ccctggcatc tacgtgctgt cgctgatgat tgggaaaaat gtggtggagg acacagagaa 360 tgggtttttc ctggacgtga accaccaggt gtcgatggtg tgcagtcagc tagctcagga 420 cccaaagctg caaggggggt acaacgccat gggcttctca cagggagcgc agttcctgag 480 agccgtggct cagcgatgtc cctccccacc aatgaagaag ctgatttctg ttgggggcca 540 gcaccaaggt gtgtacgggc tgcccaggtg tcctggcgag agctcccacg tgtgcgacat 600 gatccgcgag gctctgaaca ggggggcgta cagcgacctg gtgcagaagc acctggtgca 660 ggcccagtac tggcacgacc cgctcaatga cgacctctac aagaagcaca gcgtgtttct 720 ggcagacatc aaccaggaga ggaccgtaaa tgagacgtac aagaagaatc ttcagcagtt 780 agagaagttt gtgatggtca agtttctgca ggactcggtg gtggatcccg tcgacaccga 840 gtggttcggc ttcctgaaaa caggccaggc caaagagacg gagactctgc aagagagcga 900 cctctacaaa caggaccgct tgggcctcgc tgccatggac aaagccggaa agctggtctt 960 cctggccacc gagggagatc atctgcagtt ctccaaggaa tggttcgatg ccaacctgct 1020 gccgtacctg aggtagaggt gcacggaccc gccccctcca cccgccatga gctcctcttc 1080 ccgctgcttt aacagatcaa agttttctaa caataaaacg tctctgctgt gaatctgatc 1140 aataaagaca caaactctaa 1160 <210> 90 <211> 1162 <212> DNA <213> Oryzias javanicus <400> 90 aagcagtggt atcaacgcag agtggccatt acggccgggc gcagtcgcca gaagaagcac 60 ggtcacattt tcacctgcaa gatcgcaggc caatacatcc acttcctgtg tgaccccttc 120 tcgtaccact cagtcatcag gcaggggaga cacctggact ggatgaagtt ccactttgca 180 acttctgcaa aggcatttgg gcatgacagc tttgacccac gccacgggca caccacggag 240 aacctccatc acacctttct gaagacgcta cagggtggag ccctgccccc actcatagaa 300 accatgatgg gtcaccttca ggacgtcctg ctgaactctg acaccctcag ccacaacaag 360 gaccagtggc aggtggacgg catctttgcc ttctgctaca aggtgatgtt cgagtctggt 420 tacctgactc tatttggtaa agaactcggg gaagacaagt gccaagctcg tcagtcggcg 480 cagaaagcgc tggtactcaa cgctttggag aactttaagg agttcgataa gatctttccg 540 gcgctggtgg ctggtctgcc catccatgtc ttcaagagtg cctacagtgc cagagagaac 600 cttgcaaaaa ccatgtatgc tgaaaacctg tcaaagagac agaacatgtc agatctcatc 660 tcgatgagga tgattctgaa tgactcccta tccaccttta acgatgtcag caaagccagg 720 acccacgtgg ctctgctgtg ggcgtctcag gccaacaccc tgcccgccac attctggagc 780 ctcttctaca tgatccggag tccggatgcc atgaaagcag ctcgccagga agtacagaaa 840 gtcctagagg agtcaggttt aaccactaac ctgagagact ccaccctaaa cctgacccgg 900 gaccagctgg acaaaatgcc catcatggac agcatcatca aagaagctat gcggctttcc 960 agcgcctccc tgaacgtgcg tgtcgctaag gacaacttct tgcttcaact tgacaaccag 1020 gaggcctacc gcatcagaaa agatgacgtc atcgccctgt acccgccctt actccactac 1080 gatcccgaaa tctatgagga tccatatgag tacaagtttg accgtttcct ggacgacaaa 1140 ggccaagaaa agaacatttt ct 1162 <210> 91 <211> 1169 <212> DNA <213> Oryzias javanicus <400> 91 aagcagtggt atcaacgcag agtggccatt acggccgggg ccaccatagt aacggcgtgt 60 ctgatctatt tcaggtacct ggcgtcttta actgttcgct cttgtaaagt gtcttattgt 120 gtaacgttca ggaacaacgt tcgtggtgga gcatttaaac gtaagcattg aagggcattt 180 attgcggaag ctgcgagtgc gcaaacatcg agacaggtgt gatcttcact aaaatgaatt 240 cccaaatccg ccaaaacttc caccaggact gtgaagctgc catcaacaga cagataaacc 300 tggagcttta tgcttcttat gtttatctct ccatggccta ctattttgag agggatgata 360 aacaattacc ccattttgcc aagttcttta actcccagtc caaagaggag cgagaacacg 420 cagagaagct gatgagtctg cagaacaagc gtggaggccg catttttctg caagacatca 480 aaaaacctga tagggatgaa tggggcagca gcctggaggc tttggagtgt gccctgcagc 540 tggagaaaag tgtaaaccaa tccttactcg accttcagaa attggctaca gatcacggcg 600 atcctcatct gtgtgacttc attgagacgc attttctgga tgagcaggtc aagtccatca 660 aacagctggg agactggatc tcaaacctgc ggcgaatggg tgcccctcag agcggcatgg 720 ctgaatatct atttgacaaa cacacaatgg ctaaggaagc caattaaacc caacccagca 780 gccgcggcgg caacctctgc atgcaggctg aacactttat cgctgtgctg catatgaaaa 840 cggcaaggtc tataaaagct ataactaaag ctgcttatgt atctgaaact atcaagatta 900 ggatgttttg tgtcttgagc aataccttta tgggagctgc actgccaagg aatatattca 960 tgtcatgaac ataaatgtaa tggaaaatat tacaataata ataataaagc tgaattatca 1020 gaatattaaa agttaatctg ctggtgtatt attttatttt atggcagtga aaaatttaaa 1080 tatttttgtc atttaacact attgtcaaaa aattaagagc tatgttttac ctgcagtgat 1140 tttatccttt ttcttgtctt gtaataaac 1169 <210> 92 <211> 1150 <212> DNA <213> Oryzias javanicus <400> 92 aaactggcac aagacaaccg gatggagagt cccatcccca tcctgccgct gtccacccca 60 gacgtggaaa ctgagaagct cataaaaatg aaagacgagg agctaaagag gatgcaggag 120 atgctgaaca agatgcagca gcagatgcat gagaaggacc agtgatgtca tctgggccag 180 agctgctctg cggggccacc tgctgtccgt cccgtgaacg acagtgaagc cctcggattt 240 ggttttaaag tgtctttgaa aaaaaaaatg ctgagtccat tactcttcag tttggtgctt 300 tggtttgtct gtttaactgg agttccttct cttagcttct catgtttagg ccctcgctgt 360 gaccccggca taaataatat gaaagcatat ttaagtaagt aagtgctcag tgtgtctaat 420 ttataatgca ttgctaaacc ctttggttat aatatcagga tttgtgctgc gatatgtttt 480 gtatggaaat attttgtgat ttgttgttga tggatgttgt tttgtattat gcaactctgg 540 gcgaatgcta gcaaatgtcc tttgaacttg aggtgtccgt ccagtttcca tttgccttca 600 taacttcttt tatccaaatc caattttcct tttctttctc ttcctttttt taatatattt 660 tgtgttttcc aagaaacgga ccaggcaaac catcacctcc cagcatttta ttgagctggc 720 tgagttgaaa aatgcactta ttgccagtgg cttactgtga gttcagacct tcgagcgtct 780 gtggagaaca gggtgcatgt gcgagcatgc tgccattact cacatctgct gattgctgta 840 ggcctatttt tactgtttta gagccgagtc cctgtgcttg tacaaaatgc ctctttaacg 900 tgctgtttgc ttcaacgcca caatgggatc tctaacgagg agctgatatt ttatctgaca 960 tattgagaga gagagagaga gcgctcttgt ggatatcctc gtgagtcgtc tgtactttgc 1020 ctgaaggccg agggctcagt ttgtgtggcc tgtctgcaaa agtgtgacaa ataaactctt 1080 ttcttgtaaa aaaaaaaaaa aaaaaaaaaa aaaaaggccg cctcggccac tctgcgttga 1140 taccactgct 1150 <210> 93 <211> 1142 <212> DNA <213> Oryzias javanicus <400> 93 agttagtgtt ctgtcccaag cagaggcagt tctttttgac caggtcagaa gtctgaacac 60 caaccgtgac catgggggat tggggatttc tctcaacctt gctggagaag gtccagtccc 120 actccacagt gattgggaag atctggatga gtgtcctttt cctcttccgg atcatggttc 180 tgggagcagg tgccgaaagc gtctgggggg acgagcagtc cggttttgtc tgcaacaccc 240 tccaacccgg ttgtgagaac gtctgctacg actggacctt cccaatctcg cacatccgtt 300 tctgggtcct ccagatcatc ttcgtctcca cgccgacgct gttgtacctg ggccacgcca 360 tgcacatcat ccagaaggag aaaaagctcc gggagaagat ctcaacaccc ggcgggcctc 420 aacagtacaa gtctcccaag tacacagacg agactggaca tgtgaccatc aaagggaact 480 tgctgggaag ctatctgacc caactcattg tgaagatcat catcgaagcg gccttcatcg 540 tcggtcagta ctacctgtac ggctttgtca tggttcccat gttcccctgc tccaagaagc 600 cctgcccctt caccgtggag tgctacatgt ccagacccac ggagaaaacc atcttcatca 660 tcttcatgct ggtggtggcc tgcgtctccc tgctcctcaa cgtcatcgag gtgttctacc 720 tgatcggctc cagagtccgg tgtggctcca ggcgccgcgc ccacagagtc acctcggcag 780 aaaaccccgc cagcctttct ggtccaaaat ggtcaaacac ggacgacgct ctcaagcaga 840 acaagctcaa catggagatg gagagcaacc acagcgtcgg agggagcctg gacggagcca 900 aagaggagaa acggctactg agcggtcact gaagagctga tgtggtgttt ttatgctcca 960 gattaactta gaaaatcctc catcattgaa tgaagagatg tattctgtgt agaaaccaaa 1020 cgtgcaatac tgctgtattt atgttcttga gtcattcaat gtgttcttca gatcttcaat 1080 aactggaagg aatctgctga tttgacaaac atctgattct gctgaagagg cagacacttt 1140 tt 1142 <210> 94 <211> 1136 <212> DNA <213> Oryzias javanicus <400> 94 ggtcttccca ggatgcagca gcccttctct ggcttgtctc agcagcgacg tccccatcct 60 gtcctgcggg ggcctggcca aacgctggct ggtccccggc tggaggctgg gctggattct 120 gatccacgac aggaacgacg tctttggctc caagatccgt cagggcctgg tgaaactcag 180 ccagcgcatt ctgggggcct gcaccatcgt ccagggggcg ctggagagca tcctgaacaa 240 caccccccag agcttctaca gcagcaccat cagcttcctg aagtctaact cagagatttg 300 ttacaaagaa ctgtccctgg ttcccggcct gaaccccgtc atgcctgcag gagccatgta 360 cctcatggtt gggattgaca tggaccattt tccagatttt actaatgacg tagacttcac 420 tgagcgcctg gtgacggagc agtcggtctt ctgtctgccg gcttcggcct ttgagtatcc 480 caacttcttc cgcgtggtgg tgaccgtgcc cgaggagctg atgctgcagg cgtgcgctcg 540 catcagggag ttctgccagc gccactaccg gccccgcagc tgcgacagca acgacctgga 600 ccagtgaagc tgccgcgtct ctctgtacgt ttgtatggat gcagaactga agaagcactg 660 tgctgggact ctaccaaatc agaattcagc ctcagaattt tcctagtcat caccatggca 720 acagaaacct caaagcacta actatgacgc tggtcatttt gatatgaaaa gcagaaaata 780 tttatatttt ttacttccag ccagcagcag aagcattttt gtgcatacat gcagtttgtg 840 ttcatacatt atacatcgtc tgcaggaagt gcatcagctt ttctgatcag ttactctgtt 900 tctgggccag tgttagtctg cattgacttg ttctttatca gaactttctc tgtaaatagt 960 atgtatgtta ttgtttaaca tgtatggact tttatatttt ctgcttttat ttcaagcata 1020 aaatactgtt tggtatttct tttttatatg taattatcta ataaaatact caacaaccag 1080 aaaaaaaaaa aaaaaaaaaa ggccgcctcg gccactctgc gttgatacca ctgctt 1136 <210> 95 <211> 2040 <212> DNA <213> Oryzias javanicus <400> 95 aacatcgcta ttgagacaaa aggacggacg ccataactca aaccttcggc ttttgatcca 60 agtctcggag gaaaaaagaa aggacaaatt ttctatcgtc tcgcgagaaa cccgtcgatt 120 tttaacagca atggctcaag agacaaacca gagcccggtc cccatgcttt gtgccaccgg 180 ctgcggtttc tatggcaacc ccagaacaaa cggcatgtgc tctgtatgct ataaggaaca 240 cctgacgcgg cagcagagca gtgaccgcat gagccccctc agcccaatgg gctccgctgc 300 tagtcctacc tcagaggtct ctgctatcca gagactagaa gccagtctag ccaaggttga 360 tgcctcccct gcctcttcac cagacatgtc tagaactatt caaggatccc ttcctgtgac 420 tcagcaaatg acggagatga gcatttcgag agaggacaaa cccgaatcct tagagcctgt 480 tataaaccag cctgctgctt ctagccctac tcctgtagct tcttccagtg ttgaagaaaa 540 taagggcgac actcccaaac ccaaaaagaa cagatgcttc atgtgccgca aaagggttgg 600 actcacaggt tttgactgtc gctgtggtaa cctgttctgt ggcattcatc gatactctga 660 caagcacaac tgtccctatg attacaaggc cgaggccgcc gctaagatcc gcaaagagaa 720 ccccgtggtt gtagctgaca aaatccagag aatataagtt tgacagagca atggagctgg 780 caacaatgaa acaccacgac aaagacttga gtgtgattct ttgacaaaag cgccgacaca 840 agtggctaat tgaggatgga caggacttga tttaccaaat cacaacctca taataaccgg 900 aaaaagaaac aatttgagat cctaagcgag ggagatgcat gaatgtattt tttttttatt 960 aatccattaa attgttttat cctgtttctg tggtgtgact ttgccgctgt tatgtccttt 1020 ctttttctaa gaatatgtat tgtcctattt agagcagacc aggctaactg caggatgcgc 1080 tgtcctcctc tcacccttgc caggcgccat tttgtgccaa aacagccatt ttagccagac 1140 tttccagtgt tttgaacagg ggcaatgttt tcagactgga atcatttgcc ctccctgcac 1200 gagacaattc gacttcatct ttgttacctt tacctacctc acagctactg cgttaagcta 1260 cgttgtcttc ccttttacgt tatacaacag ttggatcatc tgtcgaatga tcgcaccttt 1320 agcttgaggt atttcgccag acgggtacaa aggaaatcac ttagcatttc acagaatgtg 1380 aacatttgcg gtggcaaccg tgttgcaggg tttaacagcc tgggttgagt tcacattgta 1440 acctgacgcc tggcaaaggg ctgtgtgcac tcctgtgcag cttgagagga agagcagcat 1500 cgattcctgg tgggcctttt gggcgaactt aggctagggt tataaatgaa aaaggggtat 1560 caatgaatga aataagtgca tgagttactc ttcattttca ctagtgtttc aaaagaatca 1620 ttggggaaaa aagttttttt gttttcctga gaaattgttt ggattatttt ctttggtctc 1680 catagtgctg gtgtttgcac atggatttta gtgcatctgt gggagtattt ttttcttgtt 1740 tttttttctt tcattgcgct aacacaaaat tcatgtaagc acagctgtgt gtgtgttggt 1800 gtgagtgttt tgctgcaccc ccgatcctat ataagttgtg gagctgcccg gtttatcagc 1860 acatgtttac agaagttaaa ggagcatgcc cgagctagat ttatgaaaaa taatagaaat 1920 caaaattaga tgtaaccttt catcagttta attgctatca gtctgtttat ctgctataga 1980 acactgtaga gaagcgtgtg tgagagtaat tgtgggcgag catgtgcacg tacccgtgca 2040 2040 <210> 96 <211> 1102 <212> DNA <213> Oryzias javanicus <400> 96 aagcagtggt atcaacgcag agtgccatta cggccggggg tgacgaggaa aaagtggacg 60 tccaaagttc aagctgctga aagaaaaaga cttagggaag aaaaagagtg gtaaatgtaa 120 agaagccttt atacactgac ataaatactt ggtgcacacg tcgcgtttta ccacagagga 180 gttttacgag tcttccagtg aaactagctt tgctttttta acagcaggct tcagttatca 240 gcatggcaga atccaaagag ctgctgcctg aagatgttgg aacagatgac tgcctgactt 300 catacaccca catctacagt ccagatttac taaaagatca ggtcgctttt atcacaggag 360 ggggatcagg aatcggactt cgtattgcag agatcttcat gaggcatggt tgtgacacag 420 tcatttccag caggaacttg gacaaactca aggaggcggc aaaaaagctg tcagctgcat 480 caggacggcg ctgtcttcct ttgtgtgtgg atgtgaggca gcctgacagc atagctgctg 540 ctgtggacga ggcgctcaca cagtttggcc acatagacat tcttatcaac aatgctgctg 600 gaaacttcct ttgccctgct tctgcacttt ctttcaacgg cttcaagacc gtccttgaga 660 tagacactct gggtacattc aacaccagca aagtgcttta tgagaagtgg ttcaaggatc 720 atggaggcaa catcgtaaac atctctgcaa cccttcagta tagaggacag gcgctccagg 780 tgcatgcagg gtctgcaaag gcagcaaatg atgctatgac caagcacttg gctgtagagt 840 gggggcccag tggggtgagg gtcaatgctg tggctcctgg accaatctct ggcacagaag 900 gctacaggaa actgggtggt ccaacagtcg aggctgcagg cgtgtttcag tccattcctt 960 tgcaacgagc tggcaacaaa acagagatgg cccactgcgt tctcttcctg gccagccggg 1020 catcttctta cacaactgga gccatcctgg ttgccgatgg tggagcatgg ctgacttcag 1080 ccaatgacgt ttccgcaatg tt 1102 <210> 97 <211> 2040 <212> DNA <213> Oryzias javanicus <400> 97 attctggatc agcaaaggat atggctccac ggttcaacaa aaaggggaag ctcaatgctg 60 atgagatcag tctgaggcca gcacagtcct tcatcatgaa taaaaatcaa gtgccaaagc 120 tgcagcctca gatgacaatg attcctccaa cgggttcacc attaggacag cttggtctca 180 aaagcactcc acctccaatt caggagaagc ctatgaaatc cagcaaaaag gcccctccca 240 ctaaagagga actgtgtaaa atgactgaaa cactagttgc agactacctg aacagcaagt 300 gcattgatga ggcaatcaac gctttaaagg agatgaaggt tccaaagcac tttgtgtctg 360 agatgttgaa caagatcata gtctattccc tggaccgatc agatgatgac aaggaacatg 420 caagcatatt aattcataca ctctgtactg agggcattgc cactggtgat aatctactgc 480 aggctttcct tactgttctg gaccagaact ccaagattga ggaagagatc cctctggtca 540 agtcctacct ggctcagttt gcagcacgag ccatcatttc tgacatggtc agcattgcag 600 acttctccca tcatctggag aacggagcac acttcccgct cttcctgctg tgtttgcagc 660 agatggtcaa gctgaaggac cgggattggc tgaccgaact gttccagcag agcaacgtca 720 acatgctgaa gatgctacct gaaattgatc aaaacaagga cagaatgctg gagatcttgg 780 agggcaaagg tctcagcttt ctgtttccgc tgatgaaact ggagaaggag ctgctgaagc 840 aaatcaaggt ggatccttct ccacagtcca tctacaaatg gatcaaggac aacatctctc 900 ctaaacttca cactgacaaa ggctttgtca acatcctgat tacaagcttc ttgcagtaca 960 ttgcatatga gatcaaccct gatgatgacg aagagcagtt tgcatcgcct agtaaggagc 1020 agctggatga ggagaagcag atgctgctgg ctttcaagcc cgttatgcag aagttcctcc 1080 acgaccacat caacttgcaa gtcagcgctc tttatgctct gcaggtgcac tgcaacacca 1140 agggcttccc taaagggatg ttgcttcgct actttgtgaa tctttatgac atggaaataa 1200 ttgaagaaga agccttcctc tcatggaaag aagacatcac tcaagagtac ccaggcaaag 1260 gaaaggcctt atttcaggtg aaccaatggc taacctggct ggagactgca gaggaagaag 1320 agtcagatga cgaagattac tgaaattcgg gccaaagcca tgtattaaga tgcaatgatt 1380 gaacttaaat gttctgtggt attttcttct acttttgtct cttgtcgtgg ttacaaattc 1440 attcaaatga ggtgtgtttt ctcaaaatca atttcctttc cttaattcag tcaagcctcg 1500 cagtagatta acattggacc tggccagggt tattttattt aatactgtgc aacattggat 1560 taaaaggtgg acccactctt aagcgtcacc aagtgctgcc ataactgcct ttcaccgttt 1620 acagaagaga acaaataatt gtttgatctg aaattgttaa tgggttttta gctgcacttt 1680 gtaaacgtga gttgttgcaa taggaagata ctctaaagtt tccttttaat tctgttactg 1740 tcaaatactg aagtctcttt ttttcctcaa gtttttccat tttaaactgg attttaatat 1800 atttaacagg ccattcacaa cttgcacaat gatttcatgc accaacattt acataaataa 1860 atcaaaagct ttttcatgta tgcaatgttt tatgctgtaa taattattgt ggcctttttg 1920 ttttccttct tttgagtcat ctgcatatac ctctgacata tctgattata cttgaatgtc 1980 tcgggttttt ttggacatta acagctcagt ctttgctatc gtcgtttgcc actcgtcaag 2040 2040 <210> 98 <211> 1073 <212> DNA <213> Oryzias javanicus <400> 98 aagcagtggt atcaacgcag agtggccatt acggccgggg agctggaggg gaaggaagtg 60 gagagtggag aaccaggagg gagcgcaggg cctggtgatc ggcgacaccg agctcaagca 120 ggtggtgtac gccttcaagt gcaacaacag caccctgcag gtcaaaggca agatcaactc 180 catcatcctc gataactgta agaagatggg cctggtgttt gacgatgtgg tcggcatcgt 240 ggaggtatca acgcagagac gtcaaggtcc aggtcatggg gaaggtcccg accatctcca 300 tcaacaagac ggacggctgc cacatttatc tgagcaaaga ctcgctgagc tgcgagctcg 360 tcagcgccaa gagctctgag atgaacgtcc tggttcccaa caaggacggc gagtttacgg 420 agcttccggt tcccgaacag ttcaagactg tctgggacgg ccagaagctg gtgaccacag 480 ccacagaaat cgccggatag atgtgacccc caacatgggc tttctccacc cccattccgc 540 aagtcccacc ccctaccagc taacgatcac gctgtagact gagattcaaa cctcatgacc 600 caccctccct cccccttatc ggccaatcac agctgcagct gtttcccacc tcccacaaga 660 gccaatcaga gggctgcttg ctccctgcag cagagcctcc agccaatcag cagcgagcag 720 cgtccctgca tcggctagca ctttcacagg tgttcatgag tttgccaaca gctaagatcc 780 tccagcatca catgacctcg aagccgcttc catcagaatt ccacggtttt cctttaacca 840 tgcgggagcg ttcggggcgt tagaaacatt ccacatcagg aaaactgaaa gctgcacctt 900 tgatccacct ggaagtttgt ccaggtgtga gcaaaacatc cttagatctt tcattttctt 960 cgatttattt ggggccagga tcagaaatgt tctcgttaat gctgagacat cattaaactg 1020 ttgcaaaaga ttaaaaaaaa aaaaanaaaa aaaanaaaaa aaaanaaaaa aaa 1073 <210> 99 <211> 1054 <212> DNA <213> Oryzias javanicus <400> 99 aagcagtggt atcaacgcag agtggccatt acggccgggg gaggaaatct tcgctttcct 60 tcacggcggg tggtgtccgg ttcgtggaac tcctccaaat aaactagatc cccctgatcg 120 atatccagat cctccgccgt aaacctccac catgatgcag atcaacagcg actcctccac 180 caacaagcat tcgctcatca acgtcatgca ccgcttcatc gcggccgcca acaacatgga 240 cgagaccatc atggtgccca gcctgctgcg ggacctgccg ctggacgagc aggcctgcag 300 ccagggggag gccaacaaca acgagccgcc ctgctccaac aagcagaggg acatgtacga 360 gcactacctg ctgctcaagt ccatcaagaa cgacatggag tggggcctgc tccgcaggga 420 gatgagcagc ggcgccagct tcctggagat ggccgtgaag caggaggagc agcagccggt 480 gaccggggcg ctgcccctgg acgacaacgc cgacctggag cggcagttcc actatcacct 540 ccgaggactg ttcggagttc tgtccaagct gacgctgcag gcggaccacc tcaccagcag 600 atacaagcgg gagatcggag gagggaactt catgcgataa ggtcctgctg gactcgaact 660 ttaacgggat atcttgtgca atctcagaac gtgaactaac ggggcgcctg tcttctcact 720 cctctgagta aagccatttt tagccgcctc cacccccatc aggaacctat gaagcctgac 780 gcttggtgga ggttcagtca cccagatgat gctcggcatg ttggagatgc tgtcctgctc 840 tcgaagctgt aaatacctgt agtgctgagc tgaggggccc tcacctgtgt agctccaacc 900 ttcccacctg gtgctgtgcc ttgactttgt cttcacttgt accctgttca gttcactgtg 960 actaatggct aatttttgtc tgtaattaaa tattctagaa atgggttttt atattgatgc 1020 agttcaacta aaataaaaaa gaaacttgca gttt 1054 <210> 100 <211> 2040 <212> DNA <213> Oryzias javanicus <400> 100 ttagccagcc tgcccaaaca catcgaccat ttctccaagt tttcaccttc gccgctttcc 60 atgaagcaat tcatcgattt cgggtccatc aatgcctgcg agaagacatc ctttgtcttt 120 ttgaggcagg aactgcctgt gagactctca aacatcatga aggaaatcaa ccttctgcct 180 gacaaactgc tcaccacccc ttcagtgcaa atggtgcaga gatggtacat tcagagtctg 240 atggagatcc ttgagttcct ggacaagaat cctgatgacc aaaagatcct cggagagttt 300 gcagacgcgc tggtgacaat ccgaaacaga cacaacgacg tggtgccgac aatggctcag 360 ggggtcatcg aatacaaaga ggtctttccc caggatgtgg tcaccaatca aaacatccag 420 tacttcctgg accgcttcta catgagccgc atctcgatcc gaatgctcat caaccagcac 480 actcttgttt ttaacggcac cacaaacccc gcccacccca ccaccattgg gagcattgag 540 cctcactgcc aagtcggaga agtcgtgcaa gatgcctttc atagtgctaa gatgctgtgt 600 gaccagtatt acctccgctc ccctgatctt gtacttcaag aaatgagcca caagaagaag 660 ggtcatccca tatctattgt atacgttccc tctcacctgt atcacatgtt gtttgagctc 720 ttcaagaatg caatgagagc tacaattgag acccatgaga ataagaacaa cctaccaccc 780 attaaggtta ttgtgtctct gggcggtgaa gacatgtcca tcaaggttag tgacgtgggc 840 ggcggagtcc catttcgcaa gatcgagaac cttttcagct acatgtactc cacagctcct 900 gccccccaga ttggagagca ctcacgaacg ccactagctg gcttcggtta cggtcttccc 960 atttctcgcc tctatgcaaa atactttcaa ggggacctgc agctttattc catggagggc 1020 tacggcacgg acgctgtcat atccttgaag gcgctgtcca cagactccat tgaaaggctg 1080 ccagtgtaca acaaaaccgc cctgaagaac tataaagtgt gccaagaagc tgatgactgg 1140 tgcgtcccca gcaaagagcc cctagatctg cgtaaataca gggtggccta gtgaggtttc 1200 agcccaggtg gtgcttcaag acgacttaca gcggagcctc cagagcgtgt ctcctatatt 1260 cccatcacct catcatctgc cggggcagat gaacaccgga ccttcccaga cctggagaac 1320 cctttcaaga ccagcctgtt tttagcatca gcatgttgtt ttcagcttct gtcatcctgt 1380 tggggttttt gtcatagacg gctacaaact ggatgtttgg gagtgctgca tcaaactggg 1440 attgactgag gtcctgcaaa ttagagttgc ctgcggggcg gccaaggtgg cgcccggcct 1500 gtcgcaggtc agcgaaagtg gaacgaggag aagaggaagt catccattga acatgaggac 1560 tttgccaaac agggaaaacc tgttgatgat gccttatagt agcagattca cccaaaggtg 1620 tgtgtcacac ctgaaccacg agaacgaata cttgcacctt gttaaatttg agagtactgt 1680 aacgccgctg gctctgcagt tctgaacaaa tgtaagcctc tgcgtgcttt gtgcatgaat 1740 acttgtgcta gcttcttttc atttcagcct tcaaaacaag aatccttgac tcagaatcca 1800 tttttttgga ccaggctgaa tatagtccat tcatttgtaa caagtacgat tgcttcactg 1860 gggaatgtgc agctccagag ggcccacttt cagtgtcgca tcacaaccag ccgtgagagt 1920 atttagcagc ttcctataga ggcggctgtt ggtaaacctc caaagggtgc cacgtttgag 1980 tttttcttcc agtttgtgat tcatcaaggc cagtttctga gtatttttcc tattctgtgc 2040 2040 <210> 101 <211> 1044 <212> DNA <213> Oryzias javanicus <400> 101 aagcagtggt atcaacgcag agtggccatt acggccgggg atttatcccg aggggggacg 60 ctgtcaaagc gttcaccgtg tcggagagga acggcagcca ggatgtggct ccacgtcccg 120 gtgttgatga tggtgacggc tgtgctgcgg cccacggctc atggaatccc gctcactcag 180 aagtgtgact catcggctga tggcagcatc cacaaatacc acgcaaagac tctaaatggc 240 agccacctcg tcaactttag tgactacgct ggcaaaagtg ttctcttcgt caacgtcgcc 300 acatactgag gatacaccta tcagtatgtg gaactgaatg cactacacga ggagctgaaa 360 cctcttggtt tcaccatgct tggatttcca tccaaccagt ttgggaagca ggaacctgga 420 caaaacagtg aaatccttcc gggcttacgg catgtcagac caggcaatgg attcgttcca 480 aacttcctgc tgttcaacaa aggggatgtg aacggaaaat acgagcagga tgttttcaca 540 ttccttaaag agagatgccc gcccgtcggc caggacttcg ggacctctga caggctgttc 600 tggcagcccc taaagatcgg cgacatcaag tggaactttg agaagtttct ggtgggaccg 660 gatgggaagc ccgtgatgag gtggcacccg agtgtcaacg tgtccacggt ccgaaccgac 720 atccgaaatt acctgctcaa actctacact caagacattt tcaattaagc agatgattta 780 actgtagtga ggtagattct agacggcatg taggactgtg atgtggcggt ttctggtaaa 840 ggaagggggc acgttaaatg aagaggaggc ttgaaagcag aacgtctgcg gagcctcctc 900 ggagtctggg ggtccagacc agcttttcag tgcattcatg ctgctctgcc atcccacagc 960 aacatgccat cttcccaaat cccagaatcc atccaccatt acagtcccca tgttaaataa 1020 aatacaacat aaaaaccgac aaaa 1044 <210> 102 <211> 1039 <212> DNA <213> Oryzias javanicus <400> 102 agggtcagcg tccggccgag aggaacggcg gaggactttg accacctccc agacgaagag 60 aaaggaaaga aaatgtggag taaatatctc gagagagagg acagtaagat cgttgacctg 120 tttgtgggac agctgaagag ctctctgacc tgcagccact gcggcttctg ctccactgtc 180 ttcgatccat tctgggatct ctcgctgccc atatccaaga agagctacgg tgaagtgagt 240 ctgatggact gcatgcgcct cttcaccaaa gaggacgtcc ttgacggcga cgagaagccc 300 acgtgctaca ggtgtaaagc ccggaggagg tgtacaaaga agttcacgat acagaagttc 360 cctaagatct tagtgctgca cctgaaacgt ttctctgaag cacgaagaac cagcaaactc 420 tccacctttg ttaacttccc tttgaaggat cttgaccttc gcgaatttgc ctccggaaat 480 agcacaaatg caatgtacaa cctgtatgca gtgtccaacc actcaggcac caccatgggg 540 ggtcactaca cggcctattg ccgcaacccc aactcgggag aatggtacac ctttaatgac 600 tccagagtaa cgccaatgtc ctccagccaa gtccggagca gtgacgcgta cgtcctgttc 660 tacgagctgg cctcctcctc gcggctgtga ggcctcctca ggagcggaga acctcgctgc 720 tccaaggcgg aaggagacgg aagctgctgc tggatttgtg tttggatatt tatttctgga 780 aaccacagct gtccacagga actcaaccag ctcttctgtg tgtgtctgtc tgtgctcctg 840 tgtcatgctc atgctgtgtg tgtgtgtgtt gcgcgtgcat gtgtgcgtgt gtgtgagagg 900 cagacaaagg caataatccc ctttaactgg ccaaccgagt ccttctctat gcactgtaaa 960 ccaaacgagc atcctgactg cgccttggtc tcttctcctc cattcttctc tgcctccaca 1020 caataaactc ctggtttta 1039 <210> 103 <211> 1033 <212> DNA <213> Oryzias javanicus <400> 103 agtggtatca acgcagagtg gccattacgg ccagtttgga ctggaagcat ctggctcggt 60 tacctgatcg gagttgacct ccgacctgcc cagcgttcag ctctgctgaa aagaaagacc 120 tgacagagga ggagggggac agggatgtaa tggcaaccgg cgagctgaac cccaaccact 180 ttcctgcacg acgggcagca aaggttgtcc agcactacct gaacacccgc tacggctccc 240 cgtacaggct gtttggtctg gaggaagtcc tcagtgccac ggcggaggaa gtggacgaca 300 ctggaagacg gtatcacctc cagatctcag cgcatgagat tatcagcaat aggaagcaga 360 agtgctcagc agaggttttc tttccgcggg gggagccgac acaaccagct gaggtgaagg 420 cctcctgtga ggagctccta cagaacacca cggctcaaga ggaggcctta taccagaggt 480 acaaggggaa ccacagcctg ctgtccgcac agtacatacc agacagccat ggtcacattg 540 agcctgacat gatgcccttc tggcacctca gcatcgtggc ttccagcttc atcatgctga 600 atgagtccac agaaaacact ctgtacaaca tggctcaggt ggcccagatc acgcagctgg 660 aaactgagag tgatgagcta aagtttgact cccacatgtt gctgcatgac atggtgtctc 720 aggaaattct acactggaag ctgcttttca cctggtctcc agcagggggc gttaaagtgc 780 agcagatgaa gcagatacca aagccagttc actgaacgtt caactcaaag tacaaaaaat 840 agctgttatt caccatgttg ccatgacact atttgtactc tttttaccgc tttataaatt 900 gtatttggca gaaggaaaaa gtaaaatgta tcccgacgac tgaaatgtat gcttaataaa 960 tttcacgaaa tagttaataa aaaaaaaaaa aaaaaaaagg ccgcctggcc actctgcgtt 1020 gataccactg ctt 1033 <210> 104 <211> 2040 <212> DNA <213> Oryzias javanicus <400> 104 aggcggcaga gaagagaggg cgtggaagac cccgtaagca gccccaggta aagacgtctg 60 acgaaccgag tggatccccg actccaaaga gacccagagg gcgaccaaag ggcagcaaaa 120 acaaggggtc cggcaagggc aaaaaagcgg cagcaactcc atcttcaggg gggaaacgca 180 gaggaagacc caagaaagag gagaaggagg aaaaggcatc ccaagagtca tctgaggagg 240 aagaggagga ggaggaggac cagtaattca acgcatgcta cctcactcaa catactgact 300 tactgttaac agaactgggc tgtatctcca acaccagtgc caccacatga ccactgttca 360 ccaaaccccc tccccctcta ctgccggaga ggggtcaaca cagtacatat atcatgcagc 420 agcactggat agaaagacgg acttgatcgt gggtagattt aagaattaca tgaatggcct 480 ttctgcaaat ctgttatcac aagtctctaa tactggacaa agtgtgctct gaggggcctg 540 gatgtttgtt tgtatgtttc ccccctcccc ctaaagatgg tctctagaat tcctctgctt 600 acctgcatct gagatggtag ggcatatttg acatttctcc tgttattatt aatttttttt 660 ttttactgga caaaggtgaa tttttacctg tttctgttca aagtcgttag cctatccttt 720 acatcatact atagttggag ttgagcttca gtgtttagga tgaggtgatt tgctagtgaa 780 aaccatctct catttttcag cccatattag agcttccctc cccagcgtcc cgctagaacc 840 cgttcatagt taggaaaaag cttcttagac ctcctcgagt cttctgtatg tagaggggag 900 atgtaaagtg tatagttggt aggttttggt tctccaggtc acatgccatg tttaaaaaac 960 atttttcttt tctttaaaaa caaaaaaaga agaaagtgtg ctgcttttca tgtaactcaa 1020 atctggtata aaaatgtttt taagtgtatc gtttgcagcg tttaaggctg agagtcatca 1080 gtgtcgtttc ttcagggagc ttttacaaat gctgttgtct tcacaccgtt atgtttttcc 1140 gagcgctcac tgattcattt tgttaagaca aacctgcaat tggtcaaagt gacagtggat 1200 agtcggtggc actactatca aacagggctg tacctaattc attccacctt ttctttttcc 1260 tcatttctga ttattttttt tactcaaatt ctcgtgacgg tttctgttcc atctactgtt 1320 ggctacagag aaatcaaagc gtgtcaggga tgctgcagtc agtccactta cttacccggg 1380 tttatttctc cacacccgag ctgctacaac ctcagtcgtg aaacccggat cactgcattg 1440 acaggcccca tcagaggcct ggaagttcat acctcactcc acagctaacc gtaccccctc 1500 ccccctatta cctggttttt ccttgttttt atggaacttt tggcatgagt tgaagatgtt 1560 gttagcttca taagttttaa acctgactgt aacattaaag atgtcaaagt ctatgtggtt 1620 tgttcgcctt ttaaattttt cggcttgttc ataatcgacg cttgtagttt ttctttcttt 1680 tgtgtgcgtg tgaagcaagt cagggagacc tgtcagcttg acgtctgtgt tcgctgactg 1740 tggtagatta gcaggtgtgt ttttatcttt tgaaactatt attctggtgc actgaaatgt 1800 tggttcaaaa tttttttcat ggacaaatgt tttttttttt cttttttgag tgtagactgg 1860 gtgctctcca ctgttctgtt ggccaccatt tttgtctttg acacaattcc cccccaaaag 1920 tgtaatccag tcgctcagtg tgtctttcat ccagctacta aatgttaatt tttttttttt 1980 tacatggcaa catcacacat cctttgattt atactgtaaa ctcaatagga tgggatcatt 2040 2040 <210> 105 <211> 1014 <212> DNA <213> Oryzias javanicus <400> 105 aagcagtggt atcaacgcag agtgccatta cggccggggt gtgacagccc ggatcagtcc 60 acgtcaacac ggcgatagag acagaggcag cagcggcgat ggacgcagcg tccccggaac 120 cctctctcta cacggtcaaa gccgttttca tcctggacaa tgacgggaac agactgctgt 180 caaagtacta cgacccggag ctgtacccgt ccataaagga gcagaggaac ttcgagagca 240 acgtcttcag caaaacccac aaagcagaca atgagatcgc cttcctggag gggctgacca 300 tcgtgtacaa gagcagcata gatctcttct tctacgtggt gggcagcgct caggagaacg 360 agttgatgct gatgtcggtg ctcagctgtc tgttcgactc cctcagtcac atcctcagga 420 aaaatgtgga gcggaagtgt ttactggaaa acatggaggg ggccttcctg gtggtggacg 480 agatcatcga tgggggggtg attctggaga gtgaccacca gcaggtcctg cagaaggtca 540 actacagggc ggacgacaac cctctaaccg agcagagtgt cacccagcac ctaacagaga 600 agctggctct gacctctaac gttctccagt cggctaaaga ccagatcaag tggtccatac 660 tgaagtgacc ccaaatgaag gaggggggag aggcgggagg acttttgttt tgtgtcattt 720 atttaactta tttggtttgt aagggatgtc acacacgtgg aaatgttttt tactcacggg 780 gatgagcgga ctggagccgt gaaggactgg agccgtgaag gacggcgccg tgagggacgg 840 cgccgtgctc cacgcgctca aacctcaagc tactttgtgt caaacacttt tgttgttgct 900 tttctgagtg gaaaaatacc aaagatttat ttctagactt tgctccaaca gatgttacat 960 tttgtgaggc tgctaataaa atagtttgct gaactaaaaa aaaagaaaaa aaaa 1014 <210> 106 <211> 1004 <212> DNA <213> Oryzias javanicus <400> 106 ctccaacctg aacaccaacg atgtgttcgt gctgaagtcc cccagcgccc tgtatgtgtg 60 gaggggcaag ggtgcaaacg atgaggaagt gaaggcagcg aagcatgtgg tcagcttttt 120 gggaggcact cccagccaag tgtctgagaa caaagagcca gctgatttct ggtctgcttt 180 gggaggaaaa aaggaatacc agacctcaaa gagcctgcag ggcatcgtca aacccccacg 240 actgttcggc tgttccaaca aaacaggaag gcttgtggtg gaagaggtac caggagactt 300 cacacagtca gatctggcca cagatgatgt catgatctta gatacctggg accagctgtt 360 tatttgggtt ggtaatgagg ccaatgaagt ggaaaagacc ggagctccaa aaatagcaaa 420 agaatacgtt gattctgatc ctgccggtcg tcgaggaata cccatcacca ctattaagca 480 gggggcggag cctccaacgt tcactggctg gttccaggct tgggattcca agatgtggga 540 gacggaccca ttggaaagag tccgagcccg tttctgagta gatctccagt cccgtcacag 600 gatgactctt cccctgctta acctggatgt gcctgcgtga ccgaagggcc accggtcacc 660 tctatgcctt gatcttggtg ctgcgcgctg gaatttatga aagtaatcct atcatgaaat 720 cacttcaaat gctttattgt gtttcagctt tttatttaga agtttttacc tcggagtcat 780 cttgaattta aacacaaata aagggctgga gactttgatc tacttctgcc atgttctgta 840 ctacacttgt gttagaggaa atgatcttct cttgcagttt cattgtatta atatcaaatt 900 tcagtgaact atcttgaact aatcagaagc tcactcctgt ctgtcatgtt ttgttctcct 960 tgctggcagc ttgtggagat cactttgctt tttcataaaa ataa 1004 <210> 107 <211> 1003 <212> DNA <213> Oryzias javanicus <400> 107 aagcagtggt atcaacgcag agtggccatt acggccgggg cccttctttt cgtttcttct 60 tgagcgcaga caataacagc tgtttgattt gagcttctgc tcctccagat ccggcatgtt 120 tggacccgca ccgcagggtg tgagcgggcg gtgaccagag tccctccacg agagagagag 180 cgtctcttcc tgcagcctcg gacgggacct gtcgtgcagg aaatggctct gatcggcaag 240 agcgcggtgg tgaccggagc ggcgtcgggc atcgggaagg gactgagcga ggttctcctg 300 cagaacgggg ccaaggtcgc cctcctggat gtgaaggaat ctgctggaca gagtttaatg 360 gagtctctga atcagcaaca tggaacagga agcgccttgt tcctaaaatg tgacgtagaa 420 tcagaagagc agcttaaagc tgcttttcag aaagcagcag aaaccttcgg aggaatcgac 480 atcttgtgca acaatgccgg cattatgaat gaggctacat gggaaaaagc cgtgtccata 540 aacctgatgg gcgtcattag agcaacttac atcgctctgg agcacatgag caagttaaac 600 ggaggtaaag gaggagtcat catccagact gcttctttgg caggtctggg tccgtttccc 660 agctgtcccg tctacacagc cacaaagagc ggcgtggtgg gcttcacacg agccatggcg 720 gttgcctctg aggtgtcggg ctacggcatc cgcttcaacg ctctttgtcc aacttttgtc 780 caaactgaaa tgataaccaa catccctgct agactgggga agttctctca cctgaatgaa 840 gtggctgaac agttaaaaga aaaactggga gttctgagtg tgtcagacgt ggctgagagt 900 ctcctggagc tggtgacgga cgagacgaag aacggggagg cgctcatgat tctcactaaa 960 ggaaaggctt acatgcagtt tccatcaccc taagtaatgt gtc 1003 <210> 108 <211> 2040 <212> DNA <213> Oryzias javanicus <400> 108 tgttgttcac attatgcctg gatattccga cagagatcgt ggcagagaca gggatagaga 60 cagaggttat ggcggaggtc ctcgttttgg tggaagtcgc ggcggcggtg ggggaggtgg 120 tggaggaaag tttggtaacc ccggagaacg gcttcggaaa aaacactgga acctggacga 180 acttcccaag tttgagaaga acttctacca gcagcacgcc gatgtggccc ggagaccact 240 gcaagaagtg gaacagtaca gaagaaccaa ggtgattacg gtgaagggga gagattgtcc 300 caaatcccat cacgaagttc catgaagcaa gcttcccatc ctatgtgatg gaggtcatca 360 acaaacaaaa ctggactgaa cctactccga tccaggctca aggctggcct ttggcactga 420 gtggcaaaga tatggtcggg attgcacaga ctggatcggg caagactctt tcttatctgc 480 tgcctgcaat tgttcacatc aaccatcagc ctttcttgga acgtggagat ggccctattt 540 gcttggttct ggccccgacc agagagctgg cccagcaggt gcaacaggtg gctgcggagt 600 acggcagagc ttctcgcctt aaatccacct gcatctatgg aggagcacca aagggacccc 660 agatccgtga cctagagaga ggtgtggaga tctgcatcgc cactccaggc agacttatcg 720 acttccttga atcagggaag acgaatctgc gcaggtgcac ctacctggtg ctagatgaag 780 ccgacagaat gctggacatg ggcttcgagc cgcagattcg caaaatagtc gaccaaatcc 840 ggcctgaccg gcagactctg atgtggagcg ccacttggcc caaagaagtt cgccagctgg 900 ctgaggactt cctgaaggag tatgtgcaga tcaacgtggg ggcactgcag ctgagcgcca 960 accacaacat cctgcagatc gtggacgtct gcacagacgg agagaaggaa aacaagcttg 1020 tccgtctgct ggaagaaatc atgagcgaga aggagaacaa gacgatcata tttgtagaga 1080 caaagaggcg ctgcgacgat ctcaccagga ggatgaggag agatgggtgg cctgctatgg 1140 ggatccatgg agataaaagc caacaggaaa gggactgggt tctcaatgag ttcaaatttg 1200 ggaaggcccc gattctcatc gccacagatg ttgcctccag aggtttagat gttgaagatg 1260 tgaaatttgt catcaactat gactacccca acaactctga ggactatatc caccgcattg 1320 gcagaactgc tcgtagctca aagacgggca cagcctatac cttcttcacc gccaacaaca 1380 tgaggcaagc cagcgacctc atcgctgtgc tgcgcgaggc taaccaggcc atcaacccca 1440 agctcctcca aatggctgaa gatagaggag gtcgttcaag aggtggctat agggacgatc 1500 ggcgggatag gtattcatct ggtaggaggg attttggtag ggaccgggaa aacagaggct 1560 tcgacaacgg acagaataaa gctttcagtg ccaataccca gaacggaggg tacggcggca 1620 tgaacaccag caacaccaac ggctacggcg ccgccggcta cggcaccaac ggacaggcga 1680 gtttcaactc caaccaggct gcagcctttg tgcagaacag cttccagccc cagcagtttg 1740 cagcggctac tgccgtcgcc cagaacggcg tgggtcaccc ctcattcccc tacgcccagg 1800 cacaggcggc cgcccagcag atcgctccac catcaatggt gccgtacgcc atgccgcctc 1860 ctcagtttcc tcagtaattg aatcacatgc gtcaaaaaaa taacttattc cccccttttt 1920 ttggtctcaa gtactcaatc aataattctt tttgtattta catgacaggg ttacgacttc 1980 aaatttatca ggacttttca cgtctgcagt gtagcaaagt tgtttttttc caagtattta 2040 2040 <210> 109 <211> 974 <212> DNA <213> Oryzias javanicus <400> 109 aagcagtggt atcaacgcag agtgccatta cggccggggg gtagttcgtt gttttgtgac 60 ctgtcagcat tgtagtacca gctaccgctg caaataaatt gttttcttag ttagcttcaa 120 atttttattt ttaccatcga tgctgaaagt attattggca ctaaaaatgc tctggaagtt 180 tttttgcatt ctattttagt catgctcgat gaacagattg ctaacggcta aaaattagct 240 aacaagccgc cccaacttca ctgccagcta gcatccaagg ctacttagca gcactagctc 300 gtctggtgac aggacgagtg taggaatccg cccaccaccc cagagcagtg ttccggacag 360 aagacagaac gacagatgga accccaaagc tcctgtgacc tgctgctgtc caggaagaga 420 aaaaaagagg actccaatgg agagacagat gaaggagaaa gaccagggaa aattcccaga 480 tgcactgtgg gattgaaaaa ccctgcgcct ttcgcagatg aaatcgagcc agatgggaaa 540 ccctataaga gagtcaccat ggaggaggca aagaggggaa cacctcctga cagacccgtt 600 cgcgtctatg cagatggcat ctttgatgtt ttccactcag gtcacgccag agcgctcatg 660 caggccaaac gcctctttcc aaatacacat ctgattgttg gagtgtgcag cgatgacctt 720 acccacaaat ataagggctt cactgtgatg aacgaagacg aacgctacga cgctatcaga 780 cactgccgct atgtggacga ggtggtgcga aatgctccct ggacgctaac gccagagttt 840 cttgcaaaac atcgaatcga cttcgttgcc catgacgaca tcccatactc atcggcagga 900 agtgacgacg tatacaagca cattaaagat gcaggaatgt tcgctcccac ccagcggaca 960 gaaggcatct ccac 974 <210> 110 <211> 969 <212> DNA <213> Oryzias javanicus <400> 110 aagcagtggt atcaacgcag agtggccatt acggccgggg gcctcaggaa ggtgatggag 60 gagctggtgg gagatgaaca cttgaactgg gggagggttg tttccctttt tgcattcgtg 120 ggagtgctgg cgagacagct gagggggcaa acggacacga acccggggct ggacctcggg 180 cgggaagtgg cgcccggacc tgtgagctgc caggcgctgg cagaaactgt agctgatttc 240 ctgggaggag acaagaaaga gtggatgcta gaaaacgatg gatgggaagg cttttgcaag 300 ttctccagaa cagccagaga ggtgagccag gactcgtcca tgaagacggc gctctttgcg 360 gcggccagcg tgggcctagc cggactcacc ttcctgctgg tgcgctagaa atgtatcccc 420 ccgttctcca ctggggggca gtggctagaa caaccctcac ttgtttctta cgattgtaaa 480 gtttttcttc atctttgttt taccacagcg caggacccat tcaaattctt cactttaaag 540 gtttattctt caacagtgca gctaaaatac ttcatttgaa aatggaaatt tagttttaaa 600 atgatcggct gccttttttc gttcatgaat tgtgtataga ttaattctag tgtaaattaa 660 tatattatat ttatatcaaa tgaagcagtg accctttttt gtaatctgca gcttcgtccc 720 tcgttctgaa gatttttttg cttttttttt ttgtaggaat atctgtgatt tacgaggtca 780 gcaacacttt ccagtgagaa tggccacaca atggtgctat taaatgttgc atagtaagct 840 aataaaccag ggaccaatct gacttttgca tttaaacaat ctatccctcg acctatgaga 900 aatatatttt tacatttttt ggttctattt atttctccct attttgtgat aaaagaaaca 960 agtaagttt 969 <210> 111 <211> 2040 <212> DNA <213> Oryzias javanicus <400> 111 ggtgaaaata aggactgcga agtgtcccct gatgctgaca atacagatga tgggtccagt 60 aaggagcgca gggtggcttt taacataggt gactctgagg acaatgactg cagcgaagct 120 accaaacagt caaagaacct cagcaatggc tctacaaatg ctcaccaagt ccacttcaac 180 agtcatttaa atagcaaaga tgcacagatt ccaaacaacg gttacaccac ataccacaca 240 gtacacaagg actctggtct ctacaaagat ttgcttcaca agctccacct ggctaaagtt 300 ggagactgca tgggtgaagg tggcgatcgt cccattcgtc gcaataacag ctatacctca 360 tacactatgg ccatcatcgg gatgcacaca gacttcagac ataaagatgg agataaccgc 420 gctgctcaag acggggataa agcccaaggc ttgggtggcc ctgagaagaa gcgcgtgcgc 480 atggacagct acaccagcta ctgtaacgca gtagcagagg agacgactcc ggaaagtcac 540 caaaatgatg tgaaacttga aattgtagga gaagatggag gtagcagcca aagttctctg 600 gatgacaaac ttgaagagga caagccagag gtctccactc tgtttcagtt cctccagatt 660 ctgaccgctt gctttggatc ctttgcacac ggagggaatg atgtgagtaa tgccattgga 720 ccattggtgg ctctgtggtt ggtttacgac tcgggcaacg tgatgtcaag tcaacccaca 780 cccatatggc ttctgctgta cgggggtgtg ggcatctgtg ttggactctg ggtatggggt 840 cgcagagtca tccagactat gggcagggac ctcacaccca tcactccctc aagtggtttc 900 agcattgaac tggcctcagc cttgactgta gtggttgcct ctaacattgg tctgcccgtc 960 tctacaaccc actgcaaggt gggctcagtg gtggcagtag gctggctacg ctccagaaag 1020 gcagtggatt ggcgcttgtt tagaaatatc ttcatggcat ggtttgtgac tgtgcccatc 1080 tctggcctca tcagtgcagc tgtcatggcc attttcatct atggcatcct ataagcacgc 1140 agttgcatcc caatccagaa gggaggagct gctacttcaa tgcttaacca gatgaggagt 1200 aatgtttcat ggccaaaata tagtgctgtc ctcaatctga caacagaagg aaaaaaaaat 1260 gtggacgtgt ttaatcaaag tatgaaagta cttgtttcat gtgcctgttg ttcctggccg 1320 cgtcatttat tttcctgtta tatcactggt ttactttaat gtaagtagaa aagcttgcat 1380 atctgttcta tatcttgaaa acatgttttc attttttttc tccaaagact atatgcaatt 1440 ttctgtgtat aattagtttt acatgctggg gaacaatgct gtaattgttt tatttcaaat 1500 tgcaggtctt ttttttaatg ttttttttct tccattatca agattaagaa accttcccaa 1560 tttcttgtat ttgttatcaa gttttttgtc tttaataact ttgaagttta acagtcacat 1620 caaactgctg ctttggagaa ctgcagcttc ctttagcatt gtttagaatg tgctgtagac 1680 acaacttcat atgtcaaaat aaaccgaatc aaaggattgc tgtaattgaa gcactacaag 1740 gaaaagcgcc cttaaaggat aaaatgtcag tattttaaat gggaacagaa tttgttctca 1800 aattagctgc atatctgcaa cctttgacaa ttgctttcaa ccgtactggt tcaccctgta 1860 gcagccattt caactacagg aacttgcatc tttgaatgaa aaaaaaatgg catgttctaa 1920 ctttactctt taacccctaa tcttccaaat acaaaagaac tggaccttca aactggagtt 1980 ggatagtatg gaatggcttg cgttttcctt ttgcgtgccg ccagtgcgtg gacggttgat 2040 2040 <210> 112 <211> 959 <212> DNA <213> Oryzias javanicus <400> 112 aagcagtggt atcaacgcag agtgccatta cggccgggga gaaccaaagt agagacttcg 60 gcttagtggg agtttttcac agctcagaaa cagtttaaaa tttttgcata cctttttttt 120 tttgtcccac agacaaaagt gaccacttca gtaagcaaga tgctacctgc aacttttaag 180 ctgtgcgctg gaatctccta tcggcacatg agaaacatga caggtttaag aaagaatgcc 240 atggtggcca ttcatcatga gctcaataga ctggcaggtc caggacccag taactggatc 300 agccaagttc ggcgtcgaag ctcccttcta agttctcgca ttgaggagga ggggttcagt 360 gagcaggaaa tgtcttatgt gaagcaaggc gaagatgcac tgcagaaggc tatcagcatc 420 ctcagcgagc aggacggctg gacggttgaa actgtagctc ctaacggaga taaggtcctg 480 agtaaggtac tgcctgacat cgggaaggtg ttcaagctgg aagtcgtcat ggagcaacac 540 cctgacagtc tttacgaaga gctggtggga aacatggagc aaatggggga gtggaatccc 600 aatgtaaagg aggtcaaaat tctccaaaag attggccggg agaccatgat tacccatgag 660 gtgtctgcag agacacctgg gaatgtggtg ggaccgagag actttgtgaa cgtccgctgt 720 acccgacgtc ggggctccac atgcttcctg gctgggatgt ccactcagca tccaaaaatg 780 cctgagcaaa agggcatcat tagagctgaa aatgggccta cctgtattgt gatgaaaccg 840 tgcgctgaac acccaaacaa gaccaagttt acgtggttac taaatttaga tctaaagggc 900 tggatcccaa agacaatcgt aaacaaagtg ctctctcaga cgcaggtgga ctttgccaa 959 <210> 113 <211> 941 <212> DNA <213> Oryzias javanicus <400> 113 ggaaaactac ggtcctgtct ggagagaaca tcgtcgcttt gcactgatga cactgagaaa 60 ctttggtctg gggaagaagt caatggagga gcggattcat gaagaaattc aacacacaat 120 aaagactctg gaaaacagca ttggaacaac cctgagtcct caggtcatgt ttcataactg 180 cgcctccaac atcgtctgcc agcttctgta cggaaaacgt tttgagtacg acgacgagat 240 gatcaaagtg attgttaaat gcttcactga caacgccaag atgaccaacg ggccgtgggc 300 tatgatgtat gactctcttc ccatggttcg aaacctgcca ctgccattca ggaacgcctt 360 taagaattat gagacatgta aacagatcgc tcttgatatc atgaaagaac acaaggaaac 420 taaagtctct ggagagccga gagactttgt tgactgctat ctggatgagt tagagaagaa 480 aaccgtggat ttgtcatttt ctgaggatcg actggctggt tactctttgg atctgtattt 540 tgctggaacg gacaccactt ccaacacttt gctgacaggt ttcctttact taatgggcca 600 tccacatata caagaaaggt gtcagcaaga gatagacgtg gtgctggagg acaaggatcg 660 ggtcagcttt gaggacagaa acaacatgcc ttacatgcag gctgtgatcc atgaaatcca 720 gaggtttgcc aacattgttc ctctcagtgt cttccacgcc acaatgaaag atactgaact 780 gatgggatat tctattccca agggcaccat ggtcatccaa aacatgagga cagtgctgat 840 ggaggagggc cagtggaagt tccctcatga attcaatcct gaaaactttc tcaacgacaa 900 gggagagttt gtcaaaccag aggccttcat gcccttctca a 941 <210> 114 <211> 2216 <212> DNA <213> Oryzias javanicus <400> 114 ttacggccgg ggatcattta acacagcaaa gaacacagaa aggagaatag ttgagagaat 60 ctgcgcagaa aggaagaggc ttctttcagc tgagactacg cgaaaggcca tcgttttact 120 gaaaaaatat tagcattggt tttcgtagat ctgtgggcat acgcgcgaaa gatgaagctg 180 ttgtgggcgg taatgctggt agtcggcgtc gtgttcgccg aggaggagga caagaaggac 240 agcgtgggaa ctgtgattgg aattgacttg gggactacct actcttgtgt tggagtcttc 300 aagaatggcc gtgtggagat cattgctaac gaccagggta accgcatcac tccctcctat 360 gtggccttca caagtgaggg agagcgtctg attggtgatg ctgccaagaa ccagctgacc 420 tccaacccag agaacacagt ctttgatgct aagaggctga tcgggcgtac ttggggtgac 480 tcctctgttc agcaggacat caagtatttt cccttcaagg ttattgagaa gaaaagcaag 540 ccccatattc agattgacat tggtggtggt caaatgaaga cttttgcccc tgaggagatc 600 tctgctatgg ttttgaccaa gatgaaggag actgctgagg cctatctggg aaaaaaggtc 660 actcatgccg tggtcactgt tcctgcatac ttcaatgatg ctcagcgcca ggccaccaag 720 gatgctggaa ccattgctgg cttgaatgtg atgaggatca tcaatgagcc aactgctgct 780 gcaatcgctt atggtctgga caagaaagac ggcgagaaga acatccttgt gttcgacctt 840 ggtggcggca ccttcgacgt ctcccttttg accattgaca acggtgtctt tgaggtggtg 900 gccaccaacg gtgacactca tctgggaggt gaagacttcg accagcgcgt catggagcac 960 ttcatcaagc tgtataagaa gaagaccggc aaagatgtgc gcaaagataa ccgggctgtg 1020 cagaaactgc gccgtgaagt tgagaaagcg aagagggctc tgtctgctca acatcaggcc 1080 cgcattgaga tcgagtcctt ctttgaggga gaagacttct ctgagactct cacccgtgcc 1140 aaatttgagg agctgaacat ggatctgttc cgttctacca tgaagcctgt ccagaaggtg 1200 cttgaggatg ctgacctgaa gaagtctgaa attgacgaaa ttgtgctggt tggaggctcc 1260 acccgtattc ccaaaatcca gcagcttgtc aaggagttct tcaatggaaa agaaccctct 1320 agaggcatca accctgatga agctgttgca tacggagctg ctgtgcaagc tggagtgctc 1380 tctggagaag aagacactgg tgatgtggtt ctcctggatg tgtgccccct gactcttgga 1440 attgagacag ttggaggagt aatgaccaaa ttgatcccca gaaacactgt ggtgccaacc 1500 aagaaatctc agatcttttc taccgcctct gataaccagc caactgtcac cattaaagtt 1560 tatgaaggtg aacgtcctct gacaaaagac aaccatctgc tgggcacttt cgacctgacc 1620 ggcatccccc ctgcacctcg cggcgttcca cagattgaag tcaccttcga gattgacgtg 1680 aacggcattc ttagggtcac tgctgaagac aagggcactg gaaacaagaa caagatcaca 1740 atcacaaacg accagaaccg tctgacgccc gaagacatcg agcgaatggt gaacgacgct 1800 gagcgcttcg ctgacgaaga caagaagctg aaggagagga tcgacgctcg caatgagttg 1860 gagagctatg cctattctct gaagaaccag attggtgaca aggagaagct tggtggcaaa 1920 ctctcagatg aagacaaaga ggccattgag aaagcagtgg aggagaagat tgagtggatg 1980 gagtcacatc aagatgctga gacggaagat ttccaggcca agaagaaaga actagaagag 2040 gtggttcagc caattattag caagctatat ggaagtgcag gtggtccacc accagagggc 2100 gctgagagtg agggagagaa ggatgaattg tagggaggtt tggcctcatt tgttgcctct 2160 tgccaccatt acagtggctt ctgcttatga aaataagact gatgggactc gatagt 2216 <210> 115 <211> 2198 <212> DNA <213> Oryzias javanicus <400> 115 attacggccg gggggagctc gcagaacggc ggcacggaag gaggccagat cgacgccagc 60 aaaggcgaag aggatgcggg aataatgttt gttggaggcc tcagctggga caccagcaag 120 aaagacctga aggattactt ctccaaattt ggcgaggtga cggattgtac catcaagatg 180 gatcagcaga cgggccggtc acgaggtttt ggctttattc tctttaaaga tgcagctagt 240 gtagacaagg ttcttgaaca aaaggaacac aggttagatg gtcggcagat tgaccccaaa 300 agagcgatgg ccatgaagaa ggagatagtc aaaaagatct ttgtgggagg ccttaaaccc 360 gacttgtcaa aggaggaaat tgaggagtat tttggagcct ttggggagat cgagactatt 420 gagcttccgc aggatccaaa gacagagaag aggaggggat ttgtattcat tacttacaaa 480 gatgagcctt cagtcaagaa ggttttggag aagaagtacc acactgtcgg tggaagcaag 540 tgtgaaataa aaatcgctca acccaaagag gtctacatgc agcagcagta tggcgcgcgc 600 ggatacggtg gacgtggaag ggggcgtgga ggccagggcc agaactggaa tcaaggctac 660 aacaactact ggaaccaagg atataacaac catggctatg gttatggaca gcagggctat 720 ggatatggcg gctatggcaa ctatgactac tctggttatt acggctatgg gggtggctac 780 gattacaacc agggcaatac aagctatggg aaaactccaa gacgtggagg ccaccagagt 840 agctacaagc catactgatc actcatagtg caggtctaaa gtaaataaaa agagatccat 900 ggtctgacca cagcgaacat gggctctggc ttttcctttg gagttggcag aaatttggac 960 tccatttgta cagatcaagc gaggaaactg gggaagcaat tgtcactttt ttttcccact 1020 ttttattttt ggttttcgtg tccatttaca tttccagcga tggaagtgtt atttttttac 1080 tgtacttttt ggtacctttt ttgaataatg tattgtatgg ttgtattttt acatgtcaac 1140 tggatttaca catgtggagg aacaagagct ttcaaagctc tcaaataaaa ttgtttagtt 1200 tttttttcct gtttttgtgt ttgtacaaaa aaaagcgttc ttcctcttgt attgaaagaa 1260 ttctgcaaga tttaagtaga aaaagaaggg ctttaacatg agcagaagtg ggtgtgtcac 1320 tttgttgcca atatcatgca gatggagtca ttccccccat tttctatttt ttgtcttggt 1380 ttttaaagtt tttctttcat gaacatgttt gcagttttaa ctggcttcac tggtgttatt 1440 caactgaatg caagcctgtt catgtaagag ggcattccct ctctcactgg agtttcattc 1500 cttaagtgtc ctggataaaa gtggtagaaa taaacttttg gttcaaatta caaaaacatc 1560 tttttgttat catttgtaaa gttaatggta aatgtatcta aatggcttgc taatttgtaa 1620 accttttccc cctggaggcc tctggaaagc attggcagag ggcctcagta tctgcagagt 1680 aactggaaat gttaatttcc atttattaca ccaacacttc tgctatagat aatggtaagt 1740 gattttcttt ggcattctgg gtaatggagt tttatgaaat aactgatcac tttaatgctt 1800 tttttttgcg ctttcatgat ttaaatgttt atttattggg agttctcaga gatgacatgc 1860 cttgttccat ggtgatgctg tgaattggtg ctgaagacct gtgaaagaac atttgagtga 1920 cagttcagtt ccaaaggagg gttctttgca gaacaatttg cttccactta gtgtgctctg 1980 gatgtaaact ttgctattgt acatgtggtt tttaacattc agcggaagaa gggaacgact 2040 gctctgcaag atgatgtcaa gctgcaagaa tgggtaacat ctctacctct gaactatgaa 2100 tgtgaccacc tgaaaatgtg atgcaattaa aagttttata caggttgagt aaaaaaaaaa 2160 aaaaaggccg cctcggccac tctgcgttga taccactg 2198 <210> 116 <211> 893 <212> DNA <213> Oryzias javanicus <400> 116 aagcagtggt atcaacgcag aggccgctgc cgaggaggag ggagcgctgg gcggctggta 60 tgtgacgctg cacatcctca atgtgccgtt ttctgtgatg gagagtgtcc agtctggaaa 120 acccctggtg gtggtgtctc tcctgcctca cgagcagaag atgtcagtga tgcacgtttt 180 ggtgcaaaga catcctagca acacagagcc gatcaaatcc aaagaggaac ttgtgttcca 240 ctgcggattc cggaggtttc gggcctcccc aatattctct cagcacacat cagctgacaa 300 gcataagatg gagcgcttcc tcaggcccga tgctcccacc gtggtgtctg tgtacgcccc 360 catcaccttc cctccagccg gagtcctgct cttcaaacaa agaaaagatg gtgttcagga 420 cctggtggct accgggagtc tgctgagctg cgaccctcag agagtcgtcc tgaagaggat 480 tgtccttagc gggcacccct tcaaaattaa caggcgctcc gctgttgtcc ggtacatgtt 540 cttcaacaga gaggacatta tgtggttcaa accagtagag ctgaggacta aatggggtcg 600 cagaggccac atcaaagaag cactaggaac acatggtcac atgaagtgcg tctttgacaa 660 ccagctgcgg tcccaagaca ctgtcctgat gaatttatac aaaagagtgt accctcattg 720 gacgtatgat ccatatgtgc cctccccgtc gccttggttc aaatcagagg ttactgtgga 780 tgtggaggac ttggaaatgg aatagaagag aaaccgagga agaatggaga caaaaataca 840 aagcataatt gcatgaattc ataaaaaagt gaaataaagt tattttcatg aac 893 <210> 117 <211> 2040 <212> DNA <213> Oryzias javanicus <400> 117 aagcagtggt atcaacgcag agtggccatt acggccgggg attcatgcaa agagagtgaa 60 agctgtgttt tatccccccg ctgagggctt taagttaatc gatggggacc ttcaccggag 120 cgtttctcat ttttctggtg tgtgtgtatc tcccagccgg acccactgtt caagctggaa 180 agatcctggt gttcccagtg gatggcagcc actggctcaa catgaacctg ctcattcaga 240 gccttcatga caaaggtcac gaggtcaccg tggtccgcac tgccaccagc tggtatgtga 300 aagaaaatgc ccctcattac cgctcaatca ccatcagtct accagaagct atttccatag 360 aagaagagga ctttttcgtc acattcttgg tcaagatgct tgagatcaag aggcatggtg 420 gttctgtgat gggctttgtg aagttctact gggagatgct aacagcattg tcaaacattc 480 atcggcaggc cagcatgttg gctgtagaaa tcttcgagaa caaagctctg ctgcagagta 540 tccaggattc tcagtttgac gtggttctcg tggaccctgg catacctgta ggggttgtgg 600 tggctcacca actaaagctg ccgactgttt tcaacgtaag atggatcacc agtggggagg 660 gtcattttgt ggtggcgccc tctccaacat cgtacgttcc catttctgga catgccgtca 720 ctgacaagat gacatttttg gaaaggacca aaaacacgtt tttctatttc ttcaacacgt 780 gtattgacaa gctggttgta tgtcctcact atgacacact agtggaaagg tactttggtc 840 aggatgtaag cttctaccac cttctacagg gggcagacat ctggctcatg agggtggact 900 tcgtctttga gttcccccgg ccgaccatgc ccaacgtcgc ttacattggt ggatttcagt 960 gtaagccgtc taagccttta ccgccagagc tggaggactt tgtccagagt tcaggagagc 1020 atggctttat cctcatgtct ttagggacac tagtgaaagg tctcccacaa gaaatcactt 1080 ctgaaatagc tgctgctttt gcacaacttc cacagaaggt gatatggaga catgccggag 1140 aacgacccga caatttgggc aacaacactc tgctggtgaa gtggatgccg cagaacgatt 1200 tgttaggtca ctccaaagtt aaagcctttg ttgcccatgg tggtactaat ggcatctatg 1260 aatccatcta ccatggagtg cccattgtag gcatccccct tctgttcgac cagtttgaaa 1320 acgttttgcg actggaagcg cgaggtgcag caaagggggt cgatgcagca aagctgaacc 1380 gccagagctt tctggaagcc ctacaagagg ttctcaacaa ttcgtcctac agagacaaca 1440 tgaagcgtct gtcgtccctc catcgggaca agcccatgca ccctctggac actgctgttt 1500 actgggtcga atatgtcatg cggcacaagg gagccgcaca tttacgtaca gagtcctaca 1560 agatgccctg gtattcctat tattctctgg atgttatttc ctttttacta gcaatcatgt 1620 tgatgctcat agctgctttg gttggattca tgcgattctt gtgcctcaag atgtgcagga 1680 ggaggaaacc aaagcaggag tgagcccctc tttagtcttt tcaaatggac aattaccata 1740 ggaatgatgc tgccccgccc ccttgtcctc aactgttatt gaaaaatgtt caataaaact 1800 tttccagaaa tcccagcatg taatcgaggc ttctggcctt ctcattttca tcttctctca 1860 acccacacat ttattctgtc aaatcaagtt ttctttggaa tgggaatcat acatcacttg 1920 ccacctgcaa cagaaaaaaa ataatgaaaa ctgtttcctg cgtgattctc ttaaagtgta 1980 ttttcattta ttagacactc atgcaaatgc tgtattgttt gtttatttaa caaactctag 2040 2040 <210> 118 <211> 860 <212> DNA <213> Oryzias javanicus <400> 118 ggccattacg gccgggggac cacagagctt agagaacgag aaaggtccac acaggtagtt 60 tgtccaccaa tgggcagtag taacatctag ctctttatca acatccagcc atccgcacct 120 ttcaaccgca tctggagcct gtcatcctcc atctgtgaaa ggcaaccatc ttccatcttt 180 gagcggtttt taccacctaa ggtcggcaaa aatggcagca attccatcaa gtggctctct 240 cattgccacc catgactact atagaagacg actcgggtcc aactccagca gcagctcctg 300 cggcagttcc gagtacaccg gggaggttat tccacaccat ccagcacttc cacggcaaga 360 ctcaggccac tggtggactt cctttttctt tgcaaaacag aaccaggcaa acggatcgga 420 caaccaaaag accggatcct acaccgtgac caacggtcag gtgtcctgca tcgccaggga 480 aatggttttg aaaagacagt tgagtgaaag cagcgaaagc ggaaaggtcg aaccaacaac 540 tccaccacca gtgtcctcct aggcccggct ccatcacccc ccacccccac cctcagcttg 600 ccattcatca catagtccag cagtggagat gaagatgacg atggcgatgt tgagggtgtt 660 ttgttacttt tagtaaatag tgtgcatgtc ctttttgttt tgtgcaatta tatgtatatt 720 gtgaccaaaa gtttaaaaaa atgtcaaaag tattttttca tgaacttcta ctttaaataa 780 taataaatag tgtctagtac aaaaaaaaaa aaaaaaaaaa aaaaggccgc ctcggccact 840 ctgcgttgat accactgctt 860 <210> 119 <211> 779 <212> DNA <213> Oryzias javanicus <400> 119 gctcctggac agcagcagca tcctgccgga ccgcatcctg ctgatggaca cgttctttca 60 gctggtcatc taccacggag agaccattgc acagtggcaa aaggcaggct accaagagat 120 gccagagtac cagaacttta agcagctcct caaggctcca caggatgacg ccaacgacat 180 cctggagacg cgcttcccca tgccgcgata catcaacacc gagcacggcg gctcgcaggc 240 gcgcttcctg ctctccaaag tcaacccatc acagacccac aacaacctct acgcgtgggg 300 acaggagtct ggcgctccca tcctgaccga cgacgtcagc ttgcaggtct tcatggacca 360 cctgaagaag ctggcggttt ccagctccgc ctaaaacacg ccactgtaca ggaaaaaagg 420 aggaatccca cattcccgtt caggatccat cgccatttct gtgttcttgt gaacgagccg 480 cctgtttgta ctaaatcaat cctcactttg ttctaacgtg acccgtcggg tccataactt 540 tagaggacgg acgtagagga tggagagcaa cctttcctgt aaagaaatga attttcatag 600 agagaacata tttatgtgag tgagtgaagc tataaaatgt gtcttcatta ggtttgaaag 660 taatccgact aatgtttgtc ttaaatgtgt gtctgctgag aatgcttgct ttgtccatag 720 ctgaaaatga cttgtagatt tttttgaaca aataaattat gattgcatct ctaatgcta 779 <210> 120 <211> 760 <212> DNA <213> Oryzias javanicus <400> 120 aagcagtggt atcaacgcag agtggccatt acggccgggg atagtgagac cccttaagaa 60 gcggaccgga gccgtccacg ataacggcag gggtttattg aggaggctcc atggctaaag 120 atccgttggc tgaagcgggc ttccactttg atgaactaaa caagctgcgg gttctggagc 180 cagatgtgag ccagaacacg gcggagctga aggaggagtg caaagagttt gtggacaaga 240 tcggacactt ccagaagatt gtgggcggtc tcatcagtac agtagacggg ttggcaaagg 300 aggcggagac tgagaagatg aaggccattg gagccaggaa ccttctgtca tctgtggcga 360 agcagaggga ggagcatcaa caactgctac aggcactgat cgctgagaag aagatgcagc 420 tagagaggta ccgggtggag tacgaagctc tgtcccgagt ggaggcagag caaagtgaat 480 tcatcaacca gtttatcctg cagaagtgag gcccaactca actgtctgaa gctgctgcct 540 acagctgcat cccctttcta ggggggggtc ccgatggagc tccaggaagc cttcctgctc 600 ctgcttgtcc cacatgtgaa gtcatgatac gacctccccc catatgagaa cagtcatcat 660 ggcggctggt ttgtttcccg caacactagg acctgacacg aatacaagct gaaacccaaa 720 cgggtctgac tcagcaggtg ctgtttccat atctgtgctt 760 <210> 121 <211> 732 <212> DNA <213> Oryzias javanicus <400> 121 tttctaacaa aagtcctctt ttgtgttaaa agtgctccag aaacccatca gagggtcttt 60 aaactcacag ctgtttgatt ctcctcatca gggagctgtc tgtggggcgg ggctccaccg 120 ccacactggg aggaggagtc atgcccaaga ttcacgccgt cgacccctgg gatggcaaag 180 acggacagct tcctgtggag gaggactacg acctgagcga cgtcgacctc gacgaagact 240 tcgacaagga cgagttatga gtctaaacag gatctgatct gactcggtcg ggtcgggtcg 300 ggtctgcgcg tcccgccccc cctctcctgt ggatgaatgg gaggcccggt tactgaaaac 360 ctcagaagtg acactttaga gacgcctgtg gttcctcaca gcatcccgga ggtgaactgt 420 cccgctcaaa gttttaatac ttttacacag ccgagggagg aggaggagct tttaaatgtc 480 ccatgattca tttcagtctt cgtgggctgt gaaagtggaa cttaagatga caaaaatgta 540 tattttctct tttgaatcca gtcaatgtga ggtaaagtgg attttcagtg tctgttcagg 600 acaggggtga gccgtgggac gtcttgtgta gatttttctt acacgacttt atttgtgtga 660 aaccaacatg acatttttgt tacaaaaata aaaaaataga aaaaaaaaaa aaaaaaaaaa 720 aaaaaaaaaa ag 732 <210> 122 <211> 733 <212> DNA <213> Oryzias javanicus <400> 122 atactttgac gacagcaagc agtttaagcc ggagcgctgg ctgagggaga acagcaacat 60 caaccctttt gctcacgtcc cctttggaat cgggaagcgg atgtgcatcg gccggagact 120 ggcagagctg cagctgcagc tggcgatgtg caggttggtt agagactatg aaattgtggc 180 aacagataat gaaccacttg atgtgataca ctctggactt ctggttccca gcagagaact 240 gccagttgcc ttcatcaagc gataaagctt catttgaaag tcttctggat gtgacgacag 300 accgtcgatg tgtctgttgt gatgatcctg acggtccagt gactcctacc actgctgctc 360 tgtacataga aaaatatcat aattgcgcct gaaatacctc attattattt aaaagtagtt 420 ttgcaactaa gtacgactga gcaaagcacc aaatgtaatg tacgatttaa aggttttaac 480 gaggcagctg tctttcaatc ttcattatca gacgtgtaga atgtagatgt taaactatta 540 ctttatacta ttattgtttt gttgtgtttg tacatatcca tatatctata tatgtatata 600 tcagtctgtt tatctttttt agtgtttatt ggtagaatcg ctactataat taatatctta 660 ttcctgtacg ttgttgtatg tagaaacata ttttattctc tcaaataaat gcatcgatga 720 atgcatcaaa aac 733 <210> 123 <211> 729 <212> DNA <213> Oryzias javanicus <400> 123 cgctcctacc cagtatctca tggaaactgc acacgacctc cgtttgcggt tgaaagcgta 60 catgcaacct cccaaaaaca agaaaggtga cacaaagccc ccggtcaagc cgtcccactg 120 caccatctac gtggccaaga gttatcctcc ctggcagcac agcgccttat ccctgcttgg 180 caagcattac aggagcaata atggagtcct tccagacaac aaagtgatag caggcgagtt 240 gggagccctg cctgagctga agaagtacat gaagagagtc atgccttttg tagccatgat 300 caaggagaac ttggagaaga atggacccag agtcttggat ctggagctgg agtttgatga 360 gagaaccgtt ctcatggaca acctggtcta cctgacgaat tctctggagc tggagcagat 420 cgatgtcgta tttgcaactg aggctgatga caaagtgaag gaagactgtt gccccgggaa 480 accgtttagt gttttcagat cagagcccgg agtgtgcgtg tccctggtga accctcagcc 540 ctccaacggc ttgttctcaa caaaggtcga catccgacag ggagatagca aagacaatgt 600 cgtccggcga ctagccaaag tcaacagact cattaaagat ttgtcccggg tgaagctcat 660 gaggtacgag gacccttgtt ttgggcctcg ccgggtgccc gtgctgggac aggaagaaaa 720 agacaaact 729 <210> 124 <211> 729 <212> DNA <213> Oryzias javanicus <400> 124 aagaggaatc atggttgtac ataggattaa gatgtttatt ttgtcactcg tgtgcttcat 60 tgttccggtc cattcatctc aattaccaaa tgccaccatc atggatctct cttacaaaaa 120 catggacttt gctatgaacc tttacagaaa aatcgccaac tatcatgaca agaacatctt 180 ttattcaccg ttgagtgttt ctacaagttt tgctgctctc ttaatggcta ctgatgacgt 240 cacacacaag gaaatcctcc aagtgtgcaa cctggagcag cttgatgtag acgaccagcc 300 acagctcatc ccaagacttt tccaagacct tcaagacaac atctcacaca acggctctct 360 gcaggtggag cagagcatgg ctctctttat ccgacagaac tttgaagttg agaagacatt 420 tgaagacgat ttgaagaatt tttttcaagc agacatcaat gttttagact ttggaaaccc 480 aaaggagacc atcaaaagca tcaatgacta tgtgagacag aagactgcag acaaggttcc 540 tgaaatgatt tccactttaa atgcaatgac tcaactcctg ctggtcaaca ctattttctt 600 ccagggcgct tgggagacac cttttaatcc cgatttcact cataacgcac cattccacat 660 tgacaactac aacattgtgc aagttcccat gatgtttgta gaggatagat tctacaccat 720 ggaggatga 729 <210> 125 <211> 727 <212> DNA <213> Oryzias javanicus <400> 125 gcagttcgcg tgcgaggatt gaaggatata gaacattgca tcatggtaca gagacaatcc 60 ttcagctgag gggaagacgc gactacttct atttggtaca tgttgtagtg tgaatgaaag 120 cttcagaggc agtcttttgg gattttgttt tgcttcatag atcatttatc cggttgtcgg 180 tgcgggtgtg tggttagctt agcggcgcat ctcgagtctt cctaacaagg caacatttcg 240 gggcaccagc ggcgacgcta agctagcatc cctgctagct tggccggtgc gctcgcgcgc 300 agctgccgcg tgggggatgt tgtccgtgct gtcgtacggt agactggtag ccagagctgt 360 catcggcgga ctctcccaga cagacagccg cgactacagt ctggtgacgg cgagctgcgg 420 ctttggaaag gacttccggc gcggcattct aaagaagggg atgtgttatg gggacgacgc 480 atgcttcatc gctcgacata gatcggcgga tgttttgggt gttgcagatg gggtcggagg 540 ctggagggac tatggtgttg atccatcaca gttttcagga actttgatga agacgtgtga 600 gagacttgtg aaggaaggac gctctgtccc cagcaaccct gttggtgtcc tgaccaccag 660 ctactatgag ctgctacaga acaaagtacc actattgggc agcagcaccg cctgcatcgt 720 ggttctg 727 <210> 126 <211> 2053 <212> DNA <213> Oryzias javanicus <400> 126 aacagtggta tcaacgcaga gttgccatta cggccgggca atcagaataa tgtggtctca 60 aagagacccc tccctcagga agtctggtgt gggcaatgtt tttatcaaga accttgataa 120 gtccatcgac aacaaagccc tgtacgacac cttctctgct tttggcaata tcctatcctg 180 taaggtggtg tgtgatgaaa acggctccaa gggctacgct tttgttcatt tcgagaccca 240 agatgcagct gatcgcgcca tcgagaagat gaacggcatg cttctaaatg accgcaaggt 300 gtttgtgggt cgtttcaaat cccggaaaga gcgggaggct gaactcggag ccaaagccaa 360 ggagtttact aatgtctaca tcaagaactt tggagatgaa atggaagatg aacggctcaa 420 ggagatgttt gaaaaatatg gcaaaactct cagtgtgaag gtgatgacag actccagtgg 480 caaatccagg ggctttggct ttgtcagctt tgagaaacac gaggatgcca acaaggctgt 540 agaagagatg aacggcaccg agctcaacgg caagaccgtg ttcgtgggca gagctcagaa 600 gaaaatggaa cggcaggcgg agctgaaaag gaagtttgag ctgttgaaac aagaaagaat 660 cagtcgttat cagggagtta atctttacat caaaaatctc gatgacacca ttgatgacga 720 gaaactgcgt aaggaatttt ctccattcgg gtccattaca agcgctaagg tgatgctaga 780 agacggtcgt tcgaagggtt tcggtttcgt ctgcttctcc tcccctgaag aagccaccaa 840 agccgtaacg gagatgaacg gacgtattgt tggctccaaa ccgctctacg tggctctggc 900 tcagcgcaaa gaggagcgca aggcccacct tacaaaccag tacatgcagc gtatcgctgg 960 catgagggcc atgcccgcaa atgccatcat taatcagttc cagccaacaa gcggctactt 1020 catgccagct gtgccacagg cccagaacag aacgacgtac tatgcaccca atcagctggc 1080 ccagatgcgg cccaaccccc gatggcagca acaaggtgga agaggtcaag gtggtttcca 1140 gggaatgccc agctcgctgc gtcagccagg acctcgcgcc aacatgagac acatgtcgcc 1200 cagcagcggc tcacagggcc caagagctgc tgggcaggcc atggctcctc gtccatcaat 1260 gggagtaccg ggtccccgaa ccatggctcc ttacaaatat gccactagtg tccgcaaccc 1320 aaatccccag gtggtgcaac ctattgccct acagcaggct cagccggctg tccacattca 1380 gggacaggag ccacttacag cctctatgct ggctgctgca ccccctcaag agcagaagca 1440 gatgctaggg gagcgcctgt tcccgttgat ccaggcgatg cacgccaacc tggcaggaaa 1500 gattaccggc atgctgctgg agatcgacaa ctctgagctg ctgcacatgc tggagtccca 1560 cgaatccctg cgatcaaagg tggaggaagc tgtcgctgtg ctgcaagctc accaagccaa 1620 aaaagatgca acccagaaag tggcgggcat ggctactgcc actgctgctg cggctacttc 1680 ctgaagactg gatgctgtaa acaaacgtct gaggatgctg agatgaacag gaacacacta 1740 cagtccttca aacatgatga aagccaagaa aaatactttc aattttactt gaatattttg 1800 aaaatcctta aaagtggatc attttctagc tgtatggtca tttttaactg aatatcaaga 1860 tcagaatata aatttacctc tcttttagtg gcaaaagagg gaagtcattt tcataaaaac 1920 agaaaggaaa gccttgaagt ttgcctttgc ttgaaagctt cacatttgat tgaaatgatg 1980 ggactcagtc cgatcatgtt aatgagtgtg tggtattctc aataaacaca tgaaatatta 2040 aaagaaaaaa aaa 2053 <210> 127 <211> 711 <212> DNA <213> Oryzias javanicus <400> 127 aagcagtggt atcaacgcag aggacaacaa aatccacatt cacttaggga gcccgttcat 60 tcagagcctc agcagtccgt cgcagagtca cgctgcggcg ctccaggagc aaaggactca 120 ggtgatcgcg aactgtagcc cccctgtcac caaaggcaac agcaaaatca caagtagcat 180 catgattaag cccaccactt ccccagtcca aaggccatcc cagattacag taagtaatgc 240 ctttgactga cccaataaca ctccatccca tcctttgttc caagtcctgc ctgtgagatc 300 caataccata gtcccatttc ctgtaccctg ataccggtcc gtcacttgtg tgttggcaac 360 agttttgatt ttggttgaat tgtttggtgc tgtgtgataa gactgaaaaa acacactttt 420 ttgactgcat gaaaactttg aagcactcat cattttactt tgatcacaaa atccaggttc 480 taacttatgt gcacttactg ttttgtactc agcggcacat atgccatgta tttagactct 540 ccacactgat gtatcgtgcc agttttatac acatattcag cattatacat tataatgaat 600 atggctgact tttcttggga attaaagtgt gcaaaagtag ctataagaaa aaaaaaaaaa 660 aaaaaaaaaa aaaaaggccg cctcggccac tctgcgttga taccactgct t 711 <210> 128 <211> 2039 <212> DNA <213> Oryzias javanicus <400> 128 aagcagtggt atcaacgcag agtggccatt acggccgggg gaccacacag gctgtcgctg 60 ctgtcccgct ccaaccttct cctcctcatc cacgctcagg gcttgggagt agacgaaaaa 120 caaaaacaaa aaaaacgtaa aactaacttt tttctgaagt tgagcagctg aaggattatt 180 caaagccaac gcacctggac ggaataattt ttgctgggtt tttttatttg tttttcctga 240 aactttacgt aaaatgagga ctttacgctc ggtgctcctg ctggtttacg ccttggtggt 300 ttgcagggtg gccagcggtg cagccgttga ccggcatgag aatgacaggc agcagcacac 360 atctgtcata aaccttctgg gcacaactag ggacatgcgg gaggaagtaa agaactgggg 420 actgagcgcc acaacagcag gaaaccagga agaggaggaa tacgatgacg atgaagcata 480 ctatgattat ctggaagagg atgaagcttc tggagactat gaaatgggct tgccaagagt 540 tgcaatgtca agcaaaccca aggatccgtc ttccatcctg gaggctgaaa aaacagaacg 600 caagacaagg aaaggaaagg gaaagaagaa gggcaaaggt ttgggaagga agaggaaccc 660 ctgcctgaag aagtataaag atttctgcat tcacggcacc tgccagtacc tgagggacct 720 ccgcgcccct tcctgtgtat gtctcccaaa ttactctggg gaaagatgtc agtttatcac 780 gttgcctgtt cagtcgccct cggggtacaa caggactaca gcgttagctg tggtggcggt 840 ggttctgtcc tccctctgcc tcgtaatcat tggtctttta ttgatgctca ggtttcacaa 900 gcggggtgcg tatgatatag agagcgagga gaaggtcaaa ttggggttag cgcctaatca 960 ctgaagaaaa aggcaaaagg tgaagaactc tacctcaaaa gaaaaagaaa tgaactgcaa 1020 caggaggtcc caggaggaaa caggaaagtc tgtaacaaaa gggggcagaa gacgtctgcc 1080 ggaagcgctg caagactgat ggaaacgatg ggcggctgca agtattccca atgggctcag 1140 aagaagaccg gcctgtccgg aactggaata caaaaaatat attaaaaagg ccctggagaa 1200 aggactacag gtgtttcagc atgaagaata aaaaaagaga ggaatcgtgg ttagactaag 1260 tgctgcctcc tggctgtgtg aacgatgaga aaacaaacat tttaaaatgg aactgaagtt 1320 tataacagcc agattgactg aacatttttt atttcaagca tttgtttcaa agcaaggtcc 1380 tttttttcct gtgtgtacat taaaaaaatt atatttatat ttttaattta tttatttaag 1440 ctaactgtat gtatttatgg tgaacttttt ttaaccacct ttagctgttt tacaattgtt 1500 actgttacgt ttcattttat atttcttatt ggactgtatt tatttaagag aaaaaaagga 1560 gaaattccac cttgaacgac tctgtagtct cactgatgta attttgtcaa tcagccttgt 1620 tttcgaaaag cactgggaag aataataata tttaaatgaa actgttttcc aagaagttgt 1680 catcctaatc agcctgaaag cttaccagtc caaccagata gactcggttg aatttggcaa 1740 ccactcgttt tgtgatcaag tcagaatact cgttgggttg agagaaggct acatcgcttt 1800 cactccttca tcttgatggc tcattgtgct caaaggccct aaacagatca tcatatgcaa 1860 acattcaaaa tcatctttgt ttctgtgcaa ctttaaaatg tacatttttt tttagcaaga 1920 actgaaagca tatatgttga attgctatgt cttacataat gagaaagctg tcttgaacaa 1980 aaatgtgaat tcaagtttgt gcttcagatc tgctgttttg gagtgatcat tttggtgta 2039 <210> 129 <211> 697 <212> DNA <213> Oryzias javanicus <400> 129 aagcagtggt atcaacgcag agtggcatta cggccgggga tacacctgcc aacatgaagg 60 ttatgctgat ctccatggtg ctcctgctgc tgtgcagcgc tcaagtgctc acactcaaat 120 gctacacctg cgatggggag aatgacaaaa tctgtaagac ggagaccgtc tgcccccctc 180 ttaaagatta ttgcaggacc taccagaagg gtgatgtgtt ttcccgaagc tgtgagagcc 240 tctgcgcaga ggactacttc accacctgct gcaccaccga tctctgctga tctaaccttt 300 taaaatcaag ataaatcaat gattatctct tccatttagt tcgtcttggg tgtggaagcc 360 aaatctggca atctttatct tttttttcca cctttgatca aaatgaaaca cagaaagtgg 420 acagttgagt ccttttcatc gtcccacagc ctggcttttt atccctcagg ccgggtgggt 480 gtttcaaaag cgggacaccc actcgcttac actcttttaa tccgctcctg atgtcactta 540 ttgggtcaca gctgcagtct tgtgctatgt gggtcactgt ctataagttg tactcctgct 600 ctcatctgtg ttaaactcat taaagaaaag tggaattaat ccttaaaaaa aaaaaaaaaa 660 aaaaggccgc ctcggccact ctgcgttgat accactg 697 <210> 130 <211> 670 <212> DNA <213> Oryzias javanicus <400> 130 aagcagtggt atcaacgcag agtgcgagga gatgctgctc cacgcttttg agggttacaa 60 cgtttgcata tttgcttacg gacaaacggg agcgggcaaa agctacacaa tgatgggccg 120 acaggaacag gaccagcagg ggatcatacc cctgctgtgc gaagaccttt tcacaaagat 180 aaacgatagc aataatgaca acaacatgtc gtactctgtg gaggtgagct acatggagat 240 ctactgtgag cgtgtgcgtg accttctcaa ccccaaaaac aaaggcaacc tgcgagtcag 300 agagcaccct ctgctggggc cgtacgttga ggatctgtcc aaactggccg tcacctccta 360 caatgacatc caggacctga tggactctgg gaacaaggcc aggactgtgg ctgcaacaaa 420 catgaacgag accagcagcc gctctcatgc tgtctttaac atcatcttca cacagaagaa 480 atacgacatg gagacggaca acacgtcaga gaaggtcagt aagattagtc tggtggattt 540 ggctggcagt gagagagcag actcaactgg agccaaagga accagactga aggaaggagc 600 aaatattaat aaatccctga ccacactggg gaaagtcatt tctgctctgg ctgaaattga 660 ctctgctcca 670 <210> 131 <211> 661 <212> DNA <213> Oryzias javanicus <400> 131 ttctttaagc tgtcctcaga actaccgcaa agtgtctgac tacacgtctg ttgtagcgga 60 tcagctgccc gaactacctg gagtgccaaa actctccact aagaatcact tattactacc 120 tcagcctcca gtccaacatc gtcattcccg ctcagatctt ccacatcgga ccatcccctg 180 cctattccgg agacaatgtt attgtcacga tcacccaggg aaacgaggaa aactacttca 240 gcacaagaaa actaaatgcc tacactgggg ccgtgtacct acagagacag gttcagggtc 300 caagggactt cctcatcact gtggagatga agctctggag acagggggcg ttcaccactt 360 tccaggctcg aatctacgtt ttcatcacag ccaacttgct ctaacatcct cagcgctgaa 420 ctgaagcgtg tcacgagaac atctagtcac taacgatgca tcttatcacc acttgtgctt 480 ttgaaacaag tctgtagcag atgcttttta aaccttgctg taaaagaaga ggacggatgc 540 ttcatgcaac ttcaggactc tatcaaagtg tatttttctc caagattgta cttaaaaaca 600 ttcatttgcc aaatttttgt aacccccaac gaaacataat tttgaaagta aaaaaaaaaa 660 a 661 <210> 132 <211> 624 <212> DNA <213> Oryzias javanicus <400> 132 cggcctgttg ctggaggacc cagtctgcta acggtgctgc tgggactcgt ctgcatggcc 60 gcgctgatgc tcccaacgct gggggagcaa gaatccacag tgcctgtcta cctccactta 120 agtgttaaca agaaacttgt tgctgcttat gttcttggtc ttcttacgat ggttatctta 180 cgaacatgaa gtgccgcaag gaggaggatc catgttttct tttttttaaa gaagtcttca 240 catcggagcc gctactgttg ttgaaccagt agagctgagt gtggaggagg ccgaggtctc 300 catcgttttc acaacgcgtc actacaaatg ttcgtacgat tttttttttt tttgatttcc 360 tgcagcaaaa gttgagctga tcctgagcga aggaatctac atgcagaaaa aaaaagctga 420 attaatgtac ataaaaccat gaagacgtca tagtgttgac tcgtaaccgt cattatgtgg 480 actcttccac gctgcagact gacagctgag tgcagttatt tgcacgtgtg gaaatatttt 540 aagaaaaaaa aaaaagcttt acgaatggat cgccattctt actatatcaa tgctccatca 600 tatgtttaat aaactttcag tcag 624 <210> 133 <211> 615 <212> DNA <213> Oryzias javanicus <400> 133 gagtcggaca ccattgccag taagtccttc agagacagtg ttttaaccga gtcctttgac 60 acggctaaag agcacatgtc agactcgagc agctccactg acgtttacca aaatccaacc 120 caaggaacgg actcgaaatt cgactccgaa cacagcacgc caagtcaaat attgttcgac 180 cacacaagcg atcgcacaga atgcgcagat gcgaggtaca ccgattctga tgttccagat 240 gaagaaaaca cgccggttga agagacggag ataaacgcag ctccgatcca gcaggagccg 300 gattctgttc aggagatcag ctgggatgat gttggcagct gcatagagga acacgcaatg 360 gagacctatg atacatgctg tgacaataca aacacaacag aatagtttct tatagcacct 420 taagttttcc tgtttttgta tcagatctta tggtcaacag acagacccct acgttccagc 480 cgcacggcaa cttttctatg acatgtaatg tcaataattg tgtgggagtc ttaattccct 540 taaaatgtag tcctaccgtc taatatatgt ggttatataa caacactcaa gcttgtacat 600 atgtttttta ctaat 615 <210> 134 <211> 612 <212> DNA <213> Oryzias javanicus <400> 134 aagcagtggt atcaacgcag agtggcatta cggctggggc tggcgtcact gagggctctg 60 ggaatgggct ccttactcga cgccatgttt gacttcagtg agaagttggg ctctttgggt 120 ctggagccag atgagatggc ccttttcatg gccgttgtgc tggtgtctgc agaccgctct 180 ggtattgcag aggtggcggc gctggagcag ctgcaggaga acctcatcaa agccctgcgc 240 tcgctcatca gcagtcggag gcccgaggac agcacgctct tcccaaagct gctgctgcgt 300 ctgccggacc tgcgcaccct gaacaaccaa cactcagaca agcttctcgc cttccgcatc 360 gacccgtgat ttcacgggag cgaggaatcg gcttttggat ccgccttcgc aagctcgttc 420 agctcactga cctgcgggac gccgatgacg atgcggcgta gggggcgggg ggtgctccac 480 aactgaaaaa ctttcctcga gttgcttcca tttgaaagaa ataaaaagct tttatttgaa 540 tatttcggga ctgtccaaac acccccacct tgtcctgcca gagtttgagt gaaacaaact 600 ttgcagaaga cc 612 <210> 135 <211> 586 <212> DNA <213> Oryzias javanicus <400> 135 aacaagaagt actttttgga gaagttaaaa cgagatgtag agttcttggc caccctaaag 60 atcatggact acagtctgct ggtggggatc cacgacgtgg agcgggccga gcaggaggaa 120 atggacgtgg aaggagcggg ggaggaggag gagtacgaga acgacggcat gggcggaggc 180 gtgctaacgg ggtccttcgg cacgcccccc gacagtccgg gaaaccccct gaactgcggg 240 gggttctttg gccccgggga gttcgatccc tccgtggacg tttacgcaat cacgagccgc 300 gacggtgctg tgaagaagga ggtttacttc atggcgatca tcgacatcct cacacactac 360 gacgctaaga aaaaagctgc acatgctgcc aaaactgtga aacacggggc gggggctgag 420 atctccacgg tgaatccgga gcagtgctcc aaacggttct acgagttcat gtccaatatc 480 ttgtcttaaa ctcatcttcc agtcgtaggt ctgcctaacc cgtcagtgta ggtccgtctc 540 cacccccccc cggccgtaat tccactctgc gttgatacca ctgctt 586 <210> 136 <211> 577 <212> DNA <213> Oryzias javanicus <400> 136 aagcaaagat gcccagactt ccctctcccc ggccacttcc tccagctcct cttgggggga 60 ccccgaagtg ttcccaggcc agccgagaaa catagtctct ccagcgtctc ctgggtcttc 120 cccggggcct ccgcccagtg ggacatgccg ggaacacctc tccaggaggc atccggacca 180 gatgccctag ccacctcaac tggctcctct caatgcggag gagaagcggc tctactccga 240 gctctctccg ggtgaccgag ctcctcaccc tatctctaag ggagcgcccc gccaccctcc 300 agaaaaaact catttcagcc gcttgtagtc gggatctcgt tctttcgttc atgacagaaa 360 acatgacaat gtagactcaa aaatgaccaa gaaatatgaa aaacaatgta tttttttttc 420 taatgtctgg atggggttcg aacaggcagc ctccgcaccc cgcagcggct ctctgtctgc 480 cagcataccg agcaagtgag ctccaccgtg tatccgtccg tgtatcctgc cttttccccg 540 tttctcactc gtggactata aactttaatc aaccaat 577 <210> 137 <211> 1919 <212> DNA <213> Oryzias javanicus <400> 137 tcaattgtgt ccgcctcgtg gctgtggagc ctcctccgtg atggcggtgt ctttgtggtt 60 tcccttcttc aggtttgtga agcacttccg tgtccccttc ttgcggttta gtgaccacca 120 tggatgtcag cggggtcacg aagctgtact tcagtgacag ctccaaagcc tcgtccttca 180 ccttttgttt ttcgttacca gataacagca gctctttttt cagcagctgt ttaactgtca 240 gataggccca aactctctgt agaatgctgt cactcatgtt gtcattgggg tccggaccgg 300 tgtcttcttc tgaaaaggtt accttacttc tgactgaaat ggccacaact tgtggattaa 360 agttttcgac gttattgtca agaatctgac cggccaccac aatctcagag ccgttatagt 420 actggctgaa attagtttgg gtcaagttgg cgccaccttc atagatcatc gtaacatctg 480 tcagcagtgg attagcaacc tcttcgtaga atcccttcaa ctgtaaatct gcatcagagt 540 cttcataaat gcgtctcgcc acaccatcgt tcattagcga cagtttttga aggaactcga 600 aactgacatc gaaaccaaag ccaaggcagt agagtgggaa attgcctgcg atgacgcgtt 660 tcacgttttc ttgtattttt cctctatttg tcacacctgt tgtagggtct ccatctgtga 720 ggaggatcag aatagatgct gaaccttctc gtttatatct tgttagcatt ttggctcctt 780 ctatcaatgc tgcatttatg tctgtggctc ctctgtcctg aatatttcgg gcaaaagctt 840 gggctgtctc cacattttca gcggttgcct gaacaagctc ttttttccag gtaagaattt 900 cactgtcaaa cgtgatcaaa ccaaagaaat cctcctcagc aaggtcactc aaaatcttca 960 ccagagctat tcgagtctgt tgcatttttc tgccactcat tgagccactc cggtcaatga 1020 caaagacaac attctttggt attcggggaa gactggacgg agcaaagtga tgcacaaagt 1080 agccgtttgc tttctggatg tcaccaaatc cattgtctct ctggacatcg tagctaataa 1140 ttaaatctcc attcagacct tgctctccac agccgtcaca cgtctgctgt tgattcactg 1200 tgggatagaa atgcacccag acctgtttgt cttcttgcgt cttggtaatg gcattagcca 1260 gttccttggt gctcagtccc ccttttacgt cgacaaaagt gatgcctgct ttttcctgca 1320 tgtgcacatc aatcttgaaa tccctgactg tctgcatggg tcgagcgtgg attttcagct 1380 catacttgcc gtgcttgcgt ctcaaaagtt cctcataatg gagctcaaag gtgacctttt 1440 tgttggcacc gacattgacc gatgtcctaa actcctccag gcttctgccc acagaactga 1500 caattccagc actctgacct cgagacacag cctctgtgta ttgctcctga gctttttcct 1560 ttgttttcac aaccccatca tatgcttgtc catctatata cattctgaat ttactgatga 1620 aggcatcttt gggaatctgg acgtgaaact cgatctcctt tgactcctgc atgcggttgg 1680 ccacgcggct cgtgatgacg gtggtggcat aacggttgct cacagttgag ttgatgtgaa 1740 agctgtagat gtcccagtca ttctggtttg gttgtgcgac ggcagaagcc agcagcagcc 1800 caaagatggt gactcccacc accgttctcc ccatgatgct tcagagccca gtgacaccca 1860 ggcagctgca gctggacttc cccggccgta atggccactc tgcgttgata ccactgctt 1919 <210> 138 <211> 547 <212> DNA <213> Oryzias javanicus <400> 138 aagcagtggt atcaacgcag agtggccatt acggccgggg accgccgcct ccactttacg 60 cacctgcggg aatgcgcccg ctcctccacg aacgcaccgc tccacgcctg cgccgtccgt 120 ccccgaggtc cctcctggag ctcatttaat gctctgcgcg ctctgctgct gctgctgaag 180 ctgaaggcag tcatgaccga ggagctgtag cctccctccg acgcagcaac aagcaatcat 240 cggtgatcac tgcgcgccct cgccatccaa agcctccgag atgaagacca ttctggctgc 300 gtactccgga gtcctgagag gcaccggctc cagcatcttc tccgccctgc aggatctgcc 360 gctgggactg tggccctgca ggtccaaggt ggagaaacat ctgcaggtca tctctgtgct 420 gcagtgggtc gtcaccttct tagccatggg tgctgcttgc actgtgctgc tgatctacat 480 tttttgcact gactgctggt tgatagctgc gatgtatact gcctggctca ttgtcgactg 540 gaacacc 547 <210> 139 <211> 503 <212> DNA <213> Oryzias javanicus <400> 139 tttccattct caccaatctg ttcagtcagg tctgagatct cctgctgcag gttcttgttc 60 tccctcttca tggtctccag ctgatccaga gcctcctcgt aggagttctt catcttgaac 120 agttctgtgc tgagagagcg agcctctttt tgagctcctt caagctctgc ctggctctcc 180 tcatacttct gcttccattc tgccaggacc ttgtcaaagt ttctctgttt cttgtccagg 240 tttgcagcaa gagcattagc tctctccaca tcaatcatga ggtcctccac ttcaccctgc 300 agcctctgct tggtcttctc caaagaggca cacttggagt tcacagcctc gatggactcc 360 tcagcatcct gcaggcgctg ggcaagtttt ttcttggcct cctccagttc ttcagtgcgc 420 tggatggcat cagtttcata tttggttctc cactgagcca cctcactgtt ggccttggac 480 attcctctct gcagctcagc ttt 503 <210> 140 <211> 468 <212> DNA <213> Oryzias javanicus <400> 140 ctctgcacat aggctgaagg ctatggaccc cagttgttag ctgcggtgcc ccctagtgcc 60 tctgtcccag accagccgct tggtgagccg cctgattgaa atcctgccag aaaccacgcc 120 cagtactctc tggccttaca cctcctggag gctgtggacg tcctcatcac ggaggaggac 180 tgaagagccg ggtcctggtc tgttatacag tcatcctcat catgtctctg tcatagaagc 240 tgcttttaaa ggtttacttc atcaggttga gtgcatgaat cagaatctgg ttgaatctgt 300 gggttaagca gagcgttgtc atagaagact tggtcctctc gtgccacatg agtttagttt 360 ctctgctctc tgttagtcaa catgtaaata aagaagagcc ttatttttac ctcgcctgtc 420 cctctatgcc caactgcttt cactaagaaa taaagaggct atgagaac 468 <210> 141 <211> 445 <212> DNA <213> Oryzias javanicus <400> 141 aagcagtggt atcaacgcag agtggccgag gcggcctttt tttttttttt tgtgtgttgg 60 ttgcggttct gttgctgctg aacctgctga atctgttggg gggctggcct ctttcgggat 120 gggtccataa ctccgggcat cccaggccga gacacagggc tgttgccata tcctgggggc 180 cccatggctg gtccctgcgg ggtcatacgg ctggatgggg gcatgcctgg tctcgggtat 240 ccaggcccag gcattggaga gcggtacatg tggttctgac cggccgacga tggtcccatt 300 cttccagtgg gagttccggg ccccatacct ggtccagcac cgggtactgg ttgtccaggt 360 ccgacagctc caccaccacc agtcggtgcc gtctgaaacc cccctctggt cgccatctcc 420 tcactctgcg ttgataccac tgctt 445 <210> 142 <211> 427 <212> DNA <213> Oryzias javanicus <400> 142 atggggacag aatggagtgc tgcaatgccg ttaccaagtt cagagatgac ttcctctatg 60 ctgactttac ttctgttcat caggtctctg actctgtgca gacgctcaca gaacggcttt 120 tctgcttcct ttaaaatcct tgcatcattg cgtgcgtctt tgttgtcctc cacttcctcc 180 atctctgcaa taagactgtt gatgaactgc agaggcaggt ccagcgctcc ttggagggag 240 aaatgaacag ccaaggcctg caggatggct ccattgtagc ccaacgagca ggagtgtgtc 300 aacatggcac caagacgagc aaacctttta acatcagccc ggtcaggaaa tgtcaaagca 360 aagggcgctg tcctcatggc ccctccattc ccgaaagatc cccgaccatt aaactgatct 420 ctggctg 427 <210> 143 <211> 386 <212> DNA <213> Oryzias javanicus <400> 143 ctgttgtgtc accttctcct ttgagaatgt taaagaaaaa gtggggttcc tgaaataact 60 caccactgtc cccaagaccc cgtccttttg gtaggcactc agattgacct gcgcgatgac 120 ccctctacag tggagaagtt ggccaagaac aaacagaagc cgatcacccc tgagacagca 180 gaaaaactgg ctcgtgacct caaggcagtc aaatatgtcg agtgctcagc cctaactcag 240 gtacgatctc actttaatct gctgtgtatt taatatttct gatctaggct gaacatgctt 300 tgtcttgtct tttgctaact gcctttgtga actctgtcta actgtgtgtg tacctgtgct 360 tgtcccttct tctcctttat ctgtag 386 <210> 144 <211> 382 <212> DNA <213> Oryzias javanicus <400> 144 aagcagtggt atcaacgcag agtagatcaa accaatcacg tctttgtgtg atgatctgtg 60 cacaaaactg gctccaaaat acttcttatc atgcgtctgg taaatgattg atgctggaaa 120 gctttttgct ggatcttgca cggatgcggt gcatgttccc tggctgatga ttaacgctca 180 tatgtgactt tgcccctctc ctttgctccc atcagatcaa tagcctggct tccaaaggag 240 agtacaagcc ctcaggtgca gccgaccagt cgtccatgca gtctctccac acttccaact 300 acgtctatta aactcattga acacttgtaa gaaaaaaaca aaaaaaacct taaaataaaa 360 gcacacgggg ccaaacatca tt 382 <210> 145 <211> 1743 <212> DNA <213> Oryzias javanicus <400> 145 aagcagtggt atcaacgcag agtggccgag gcggcctttt tttttttttt tttctattaa 60 ctttatattg ttgcctgtgt ctcctgatca accacgcctt gctgtgtcag tgaaaggcac 120 tgtggagaag taattactgc tactgcatta cactagactg acatcgcaac aatgcttgat 180 atctcactgc aggacctcca aactttatgc ttgtctgttg agtttatgaa atttacagtc 240 aaatttgttt atttttttta ttgtatttgc tgttgaaacg taatgctcga agatcattgg 300 gtgaattttt aggtgactcc tatcacagtg agatgattta actcttcgac ccctttagca 360 taaaccaaac agaacaaaca gtgatgtctt tggatgtctg agcctctatc agaaacacat 420 gtataagcat cagcagaaaa tttggtttaa attctactac tacagctcct ccacagaagc 480 catgggatac agtggtagta atgcttgtat gtgtgtgcat ttttttcact ttccttgata 540 ggcctaaaaa ttactttgct ttaaataatc caatataaat tgctaaagaa ggatcttcaa 600 aaatttggaa acaagcaatg tataagccat tttatggtta cacacaaaat ataatctcta 660 gggagggcaa atcttaaaaa aataaaataa aaagaaagaa tttgcatttc accaatacat 720 ttctttgtgg aaacattttt aaccccttca agtttacaca cttgatctca aattcttttt 780 aacccccaat gctaacaaaa atgaaaacgg agaacgcgta cgcaagctgt acacacggac 840 tcatattgac caacatacac acagtcagaa ataaaaacac acagccctac actaggacct 900 cacagtaatg tagctccaga tgaaagagcc caacagagag attgccattt tgcttgagtg 960 aaggtgtttc agggagttgg agatcactgc ttttcagatt cggtcagcag ggtgttacga 1020 acttggggat cgtctgattt tgcctctggt gcatctgttt tttgtggagc ttcaggatct 1080 gcctgtttaa agcagagttt tttcttctga taggcaaagt atccactgat ggctccaact 1140 gcagacacaa cgatgcaaga caggattcct gctagagctc cagagccgga cttttgtgaa 1200 tctgactcgc ttcctatcgg ggcactattt cccccatcgg gaagctctgc tttatcgcgt 1260 gaagcagtaa cagctttgat tagaggctct tgatgcaaca tccttccacc aggtttcact 1320 ttatcagtag ttgttttttc aatgggtggt cctgtggggc cttttgacaa aacagttgtc 1380 tcctcagcag cagcaacttc agttgttgtt gtctcaccaa cttgtcctgt ctccccgttg 1440 caacacgcag caacagttgt agaagtggtc atctgatcac taactgctgt tagcgttccg 1500 gacccctcaa tgtcactttc tactgtggta gcagttgttg tggcatctac tgtatcatct 1560 ggatttcctt ctgaggatgg aacagtatct cctgctgctg ctgttggagc aagtgtttca 1620 ggctggattt cttgcgctgg ctcaggtgta ggctcgggtt caggctcaga tgcaggctcg 1680 ggctcaggtt caggctcggg ttcaggttca ggttcgggct cgggttcagg ctcgggttca 1740 ggc 1743 <210> 146 <211> 354 <212> DNA <213> Oryzias javanicus <400> 146 gtcgaaacgc cttccgtaaa aactagcgta accagttttt agaaaggaca atctccggac 60 cagcacatgt taaaaaatct atctggatag ttttgtctca gtgggtaaga ttgggctttt 120 tgttgggtaa agactgcgtg tgtgtgtgtt ttagaggatg agtgggttcc tgctggtcct 180 ttgtcttgct ttgtggcacc agggggggac agcggggccc gacccgccag gctgcagcag 240 ccctgatgcg gtgagggcgg cagaagaggc tctggagcag atcaaccagg acaggacaag 300 cggatacgtc ctgagcctca atagattgta tgatgtctcc cacactccac agca 354 <210> 147 <211> 332 <212> DNA <213> Oryzias javanicus <400> 147 tgccaacact ggagtagtca gatccgtctg tgggagtgcc ggcgtgccgg acggtggctt 60 taccagaagt cttcaacctt ttgacttggt tgtctgcgaa ctgagaaatc aaggatccag 120 acttccacgc tgtaactacc ggggccgatt aactaccaga tacatcaaaa tcaaatgtga 180 ggaaggcttt ccggtgcact ttgatggtga catcatgctt gtgaactagt gattatttgt 240 tgtgagagct gatcaataaa agtgttgact tgttgtagta aaaaaaaaaa aaaaaaaagg 300 ccgcctcggc cactctgcgt tgataccact gc 332 <210> 148 <211> 273 <212> DNA <213> Oryzias javanicus <400> 148 cactgacagc cacaacagtg gcaccatttg tgctgccgtc ggcaggattg gctctgggca 60 atgtctataa acaaggtata cggctttgat accgaattga ccttgcagaa atgtttaaat 120 gatgtcaacg aagcgcgtta caggtaggtg gtcctcgaat gtgcctctgg cggatgagaa 180 cgcgggcgtg gtgaatgctc ttggcaagac caagcttgaa gacctgcgtc tgcagccttc 240 tttccaagaa atcctcaacc ttcagaccca ggg 273 <210> 149 <211> 273 <212> DNA <213> Oryzias javanicus <400> 149 aagcagtggt atcaacgcag agtggccatt acggccgggg atagttactg tttcagtcac 60 aaagagaaag atgatgctca aactgggggt tttgctgctg tcagtgacca ctgttctctg 120 tcagtctgct ggtgtcgctt cacggtacag aaagtttatt gagcaacaca ttaacacggg 180 aatgattgcc aaccggtgcg acgcagagat ctctagaaga ggcattgcca aaaccaatag 240 caatgactgc aaggagacca acaccttcat ccg 273 <210> 150 <211> 1664 <212> DNA <213> Oryzias javanicus <400> 150 gagtcggacg caggctgagg agatgcttca agacaaagct caaggaacat tcctgatccg 60 tgagagcagc aagcagggat gttacgcctg ctctgttgtt gtgaacaaag aggtgaagca 120 ctgcaagatc tacagcacac cacatggata cggcttcgca gaaccctatg acatccactg 180 ctcgctcaaa gacctcgtcc tgcactatcg cctgcactcc ttagcgcaac acaacgacgc 240 cctggatgtc cggctgtcgc acccagtgaa cgccaaagat gccacagctg ctgcttctca 300 acagacagag gagaacaaac ttttacagac tccaaaacac acgtcgggac tccctcccgc 360 cgctccagag atgtgatctg gcggacgaaa gtggactgta tcctgcgaga gcaactgtgt 420 ccgagggtgc aatgtgttaa gttttgcact acagtgattc catcaggatt tgtgaatgga 480 atttttcaga gtgaagtggg gccggaactt gaatgtcagc ttgactgttc aagcttttcc 540 aaccaatttt atacttcatt tattgctgtt cgttcaaaag gactctttct ccggcgggaa 600 tgttgctggc ctgaacgatg ttttctctgg ctccaggttg ttgcacttcc agactgccgg 660 agatatccat ttcccaaatg tatccagttc agaaaatcca accaatatgt ttaatatatt 720 gggttgttat tacaaagtgc tttcgtgaat aagtgggggg aaacggtgct tttaacaggc 780 agatcgcatc ctaaaccgtt ttgggttaaa attgccacat gtgaatatat aaagttgtga 840 tgcatcttaa ctgtttgccc ttttcttaag agacattcat atacagtgga taattatgta 900 gcattaacat actttagaaa atgatagtaa aagcatactc aatgttatac ccattgacca 960 aagcacttga tagtgaggaa aattacatcc ctgtttagtg tggtcattgc atttgggcaa 1020 aggtagggca agttatgtac acctgctgat acgctgatca aaacataatc tgaagtactg 1080 tatgttatat tctgttactc aaagaagtat aagctttttg tattctatat atattttttc 1140 tataaacatg ccacaagatg aaagcttgaa gaaagtgcaa tccaacagta ttctattgtt 1200 gcaatgtata atggcggtgg cagcggtgga gacgataatg ctgtttcgag gggtcggcat 1260 ttgccacaga aatgcactct ccctggtggt gttgatatag tgtggcctcc gatgtttgcg 1320 tgaactgcca gaggtccgga agtatcctgc ctccattact tgaactgtgg cattgctctg 1380 gctatgaatg tttttcatga catgcagcct gcatagctga tgaggaaagg aatccatgtt 1440 gatcttggca catttttcaa gtttgaggac aatagacact ctgtatagag atgccataaa 1500 aatgtagttc tgacgttggt gtgtggaagg aggttaatga tgcctcttga aaaatattac 1560 tctactggag gactgaggaa actcctcggg tgaagctaag caatgtgaga tcttgacctt 1620 tttcttgctg aaagacaata aactgaagag agtttttgta aaaa 1664 <210> 151 <211> 1651 <212> DNA <213> Oryzias javanicus <400> 151 aagcagtggt atcaacgcag agtccattac ggccggggat tgctcgtatg tccgagtccg 60 ctccctacag ctatttccac cgcggggttt gtcagagcgg ccttccagcg ccgggacgat 120 cggtttagat ggcgaaaacc tacgattatc tcttcaaact gctgctgatc ggagacagcg 180 gagtcggaaa gacatgtctg ctgttcagat tcagcgaaga ctccttcaac accaccttca 240 tatctacgat aggaatagac ttcaaaatca gaacaataga gctggacgga aagagagtga 300 aactccagat ttgggacaca gcagggcagg agaggtttcg caccatcacc actgcttact 360 accgaggagc tatgggaatt atgctggttt atgatatctg caatgagaag tcttttgaca 420 acatcaaaaa ctggattaga aacattgagg agcatgcttc atctgatgta gaaaagatga 480 tccttggtaa caaatgtgac atgacggaca ggagacaggt gtccaaagac agaggggaaa 540 aactggctat tgattataga gtcaagttct tggagacgag tgcaaagtcg agcctaaatg 600 tagaagaggc tttctatact atggcgagag acattttgca taacttaaac tcaaagacag 660 gtgacagcag tggcgaaggg tcaggaaaac ccgtcaagat caccgataaa aagtcgaaga 720 agatcaaatt cttcaaatgt tcgctcctct aggctgctcg cattggaagt ttgcgttttc 780 cgcctgaact tttggacggg ctctgcctcc caggacacac aaggctctac tgccacttca 840 ggtcacgcgt ggtcgagctg ccacctcgat ttgataacta gaaagggtat cgatggggta 900 tgaggcctgg tgatgcataa ctactcgtgc aaaaagactc gatcatcagc agtggtttgt 960 agcttgccct gcagtgcctg ctccctgtgg attctagtcc aacatcagtt ggatatatat 1020 atataaataa aaaaaaaaga agttgcacaa tttagtctta caaatgaagg aaacattatt 1080 ctttgttata ttgtagcatt attttataca tcctatttac tctaaaaatt tcctataaaa 1140 tactgtgaga taagcatagt tcagcactga ttgtatttat gtgtgaattc ttgtatacta 1200 tgaagcttat ggccttcggt tgcactcatc ttttctgcct caaagaaatg tgatggagaa 1260 gacgaatata tggatgaata gatagatgca gtgttttttc atattttatt catccttttg 1320 cagtaaaatc tgtatttaca caggcctgtg tctaaatgaa actgaaagaa gagcgtactg 1380 ttatacaaat gtcaatattt gcatgtgaga tttagggagg ggacttgagg tcacgatgaa 1440 gaagagtgcc caaagaatga caaattccag tgttagaaaa actatcatat acagaatgtt 1500 ggagtttttt gccgtcgagt gtttatgcat gtttttgttt ctgactgtaa gacattcgaa 1560 atgtgaaagt agccgctgga agaaagccgt gttgtgattg tttttgtgta aattcctgta 1620 tgttacactg atgatgaaaa gtagtacaag t 1651 <210> 152 <211> 173 <212> DNA <213> Oryzias javanicus <400> 152 gtgacaggtc aaattatctg catgggtaaa agttttctta caaatatcac aaggaggcct 60 ctcacccata ggagttatca tgtgggcttt aaaggcagtt actaaagtaa aactttttca 120 catactttac aagtgaacag cttctcacct gtgtgagttc tcatgtgctc aat 173 <210> 153 <211> 167 <212> DNA <213> Oryzias javanicus <400> 153 gaaatcctcc tcctcatcac taaaagacat gactttgtat ctgcgtcctc atctggactc 60 tcctctgctt cattcagggt tctgttggac aaaatgttgt tgtgactcag ccagcagcta 120 aatcagtgca gctcagtcaa accgtctctg ttgactgtaa ggccagt 167 <210> 154 <211> 2040 <212> DNA <213> Oryzias javanicus <400> 154 tgacgtagaa aatatgctgg atgggccaca agctcctcga tccattctga tgctttcact 60 tgcagacaaa tagacccatg tacagtcttt gttttcttca tctgagctga attctggcta 120 aaaactgttc gactggatgg ctccagtatt gctaactatt tttgttttag gggctgttag 180 caggtaagag cgcattaacc ggtagttctc agttatgggt gatgggtaaa ggagtggggc 240 tgctccaact gtcccgccca caagtcagag acaaattttg aaagatcaac tgcagcactg 300 cagaaatgat ctccgaaaac acaacacagg ctttttttga tttgggttcg aataaaacct 360 ctgataatgc tcttacaata gattacaaga tcattggagc gggtctttaa attaaatctg 420 taaaatacaa gcaatcgctt taatataatg aacagcaaag tagattttag attacaagat 480 gtagaatagg aaaattacca catatttaac aaaacataag aactggcatt tggatttaaa 540 aagaattgat gaaagtttat aaagttattt ctaacagtca agatttcttc taacaaataa 600 atgaaattga actttgtatg gcaaatagaa atttaaaaag attaacatgg tttcgaaaat 660 aaagtcatac attttcttaa gcgctcttac acatggatgc ctatttgtct gcatacaaac 720 cggttctcta tactgtgtag aagctggatt atttaaaaca aaacaaaaca acaattgatg 780 catagttgac catcatgttg actgatgcag gaaaacatct gcagatgcag acgcagttac 840 atgctacaac cggactcgga gagctcgttc acagcagtgt tgaggcttct gcatttgtcc 900 tgcatgctgg aacattctgc aggtaaaggc cagcgctcca cccaagtgtc cttccccaat 960 gtgtagatga atctgttggt gtctggatca gtcttccact ggtcttcttt gggacccata 1020 aggaggtatt gggaaccctc cttcagctgg aggtcttctc tgcagcctcc atgagacatg 1080 aaaagcctcc tttcaccaac ctcgactcta tcttccacac ccagtttaat gacctgcgta 1140 atttccatct catatttgtc atagtaacct tgactgatgc tcagtacctt cacctgaaaa 1200 acgtggtgta agccgttgca ggcaaatatc tctctctcct tgttcgagaa agtgttgttg 1260 tcagcttttg acacacagca gtcgccctgt gcacagcggc agacgttgtc cttgcagatc 1320 tgagagagct cctccttgtc ctctttgggg gtgtaagtcc ggctgcagcg gtgatctggg 1380 ttataatact catagaccgt caccgaagat ggttggagga ggcccacttt aaagttctgc 1440 tgaaggcgga agatcagaat ctctggctct ttgtgtgaaa ccttgaacag gtggacgatc 1500 agggagcctc tttcactcaa attatctaca gtctggaagt tgctgatgta acgatccact 1560 gagttggaca acatctccag atcagagttt tctggggtga atccagtggg cagactgata 1620 tcaagcacca ccatccttac atctctgggt cctaacgctc tgactttgat ggtgatctgg 1680 tatgctttta ttacatctgc aggacgcttt tctgtggatt cttctatgtt cacactgagc 1740 tcaaagtcat tgcagggggt tttctcatcc acctcaagaa gctgattgta atacgtcaca 1800 acctccagta ttccctctcc acttccttta accaccacgt caaactcatg acctgcaggc 1860 agcttggaag agcgagcagc gtaggcggtg tcaggattga agcgatagcg caagtctctg 1920 cgccccggta tcttaatgtc tacatccagg ttggtgtcct cgcgtggttt gttgatcatg 1980 tactctgaca gcgcctgaag taccaccatg gtggactgtg tagagccgaa gccgccgcct 2040 2040 <210> 155 <211> 109 <212> DNA <213> Oryzias javanicus <400> 155 ctttctgctg gtaaaatcca ggaaagagcg aagctgactg agtttctggc caagcgtcca 60 ttgggtgcac gataatcctg tctgacttct ccgtcagcct ttccacaga 109 <210> 156 <211> 1595 <212> DNA <213> Oryzias javanicus <400> 156 caaaaaaaaa aaaagaattc aggcaccaga tcccaaaatc taaatgtagg tctaaaggag 60 ctctatagaa ctagagcttc aaaagaagat tgtgcttcaa ctataaaatc ctctccaaaa 120 cactttgtct ctttaaaagc cagtcagcgg tcaggagaac ttcaaaataa aactgatttc 180 tgtctttaga tagaagagca caatgctaaa atgcttgcat attttcaatg gagggggtgt 240 gtccaggggg cagggttata taatatataa ggaaagggga atgggactgt ggcaaaaatt 300 gtgcagcaaa ttaggatttg gttttacatg acaaaatagc ttatgtacat tgtagttatt 360 ttgtgcaatt tttcttgttt tgtttttttt ttgtcgcctg acaacaacgg cggatcaaca 420 gaagcggatg ggcacttcta ctcttgaccg aaaccttctg tttcctcgat ggcgaacagc 480 agcttctcct ttagctgctc gtagcttttg tagggcggca aatcgagacg attaaaacac 540 gtgtgactcc gaggaagcca cgtgtctttc cccactttct ctatgcagaa cttctgaggc 600 ccgttgcttc ccatcagttc agcaaagccg cccagaggaa gcctgcaggt tccagtgaca 660 aactgcatga gacgcagtcg cacctcgttg tccacctcct tcaccagctg ccagaaccag 720 atgatctgct tgctgttcct ggtgtagtga cggtacactg tgtttctctg ccagtcctgc 780 aggtccacct cctgcatccc acacagcatc acctctaact ccttctcatc aaagtactgc 840 agccactgaa ggggaacaac ctcattaaag ccatccagga aagccttggt ctgaccttca 900 accccgcggg agaacctcca ctctgccatc aggctgatgt actcctcctt gttctcctcg 960 gtcacttgga tgttgacacc atcaggtttg aggtcatgag acgtgatctt ccccaagatc 1020 tccatgtcta cggagaaaaa catctccagc ccacattcct cgatgtcgtt gtccctgatc 1080 caaatgaggg agttgtagaa ttccgggtcg atggactcca ggtctttgag tatcagcttc 1140 ttgttgagca tgcgtttata gaaaggcaaa gagaagcctg tgtcgatgaa cttcccatgg 1200 aaaagtgcca ttgctatgaa gcggccaatg aagcagaagt aggacaggtg gtcggggttg 1260 atggcagagg ccgggttgat ctgcagacag tagttgcttt tgccggcgta ctcaaacagg 1320 cagtacatgg ggttcagcac ttcatgggac aagaggaaaa accattctcg agccaggcca 1380 ccatagtcta gcccctcctc ccctctgaaa ataacataca gcctcctcct caggtcatac 1440 ggtttgagag ccataatttg ctgaaaagag tcttcaaaca gcgtctgcct ggaaacgttg 1500 atcttcacat ggctggggag ggcgttggac tgacacaggt aacggaaatg tgcgagtttc 1560 caccggaagc tgcgctcgta ggcaatctga gggcc 1595 <210> 157 <211> 1596 <212> DNA <213> Oryzias javanicus <400> 157 gggttttcca tggcagatgt cattccctca acctcggggg gccagggcag taggagaaag 60 ttcaagacct ccgccagaga acacagatca gtcatcaaca gctgcagcag cgacagtgtt 120 tgttaaaagg gagagacaga acatagaccc cggaaagcac taaagcatca ccataacctc 180 ctgacggagt ctgggtagta gcatgaaacc agtttgtttt tgagttgaca aggtgtgatt 240 gaccatataa ttttcctact gaactgtaga tatcctattg taatgttgtt tatacttgcg 300 ttttataagg ctatttgtga cacttcgcta ttccgaataa atatacatga aatattattt 360 agattttttt atctggggaa aaaaaaaaga aatcatttgt taaatatgtt ggaatactca 420 acacggctcc tttttctgtc gaggaaaaaa aaacattttt tgtgatcgct tcttctctgc 480 aagtgcgcaa caacttgaca tttagttgac ttgtagggtt acgacaagcc tttacccccc 540 accaaaaaca gaaaaaaggc taagcaaaca tatactcatt ccacctgaat gattatattg 600 atacactgaa ttctagattt ttgcaatgtg aatgttgatt gattttcaag gatttataca 660 gtgccatcaa tgttatagaa atgtccaata tgtgtaactg ttcaaaagtg gttgttgaaa 720 tacaaaaagt ttgggaactg aaattttttg atggtatcat accaaaaaca tgattgtggt 780 tactaataat ttatttataa tctgctgttt ttgatagttg cattgactaa gtgtaaatca 840 ttgtctttag taacgctgtt ctttctatgt tgttagtgta atcccaatat attgtagcta 900 ttgacattgt atgtttgtat cagacatatt acacaatgca cagtacatac agattttttt 960 cccccatgat aatggaccta atctcattaa acaacacttc tacttggttt gaccactcat 1020 tctgatattt acacttttac cgcgtccttt ttctgtttag ctttgacatt gttttaaggt 1080 gatgcaaaca tctattcctt gcaaaaaacc acctattaat ttcagaacag gacaagaggg 1140 gggatgagat attaagatga ccgaatgcgc ccccttgtgt tagagcggtg caagcgcccc 1200 tctgccatca cgtctggctt cactttctgt cctcacggat aaccagctaa tcacgccatg 1260 cagacgaacc tagcaaaacg ctgtaacgga gctccgacca caggacgttg aggttacaca 1320 cgacaggaaa atggaccgag cagccagatg aagggctaca aaatgtgtgg attttactcc 1380 gaaaatgctt atttttagtt ttgcaaatta aaaaaaagga acaaaacctt aacatgagac 1440 attaccatac ttgcactttt gaaaggtata ctgtaactac tggcagtttc ccaaggtttt 1500 tagtcttttt gtttattttc tttgcactat aggcaaaaag cacatgtgag acttttttgt 1560 atttgacttg cttaataaat ttattctaaa tgtgtt 1596 <210> 158 <211> 1568 <212> DNA <213> Oryzias javanicus <400> 158 ttttcagctt tccggtggat aacctgcgtg cctctccatt cctgattcag tatatccaag 60 aggagattcc tgattacaga aatgccatca ttgtggctaa aatctcctgc tgcagctaaa 120 agggctcagt cccatgcaga acggctccgc ttgggtctgg cagtgattca cggcgaggcg 180 cagtgcgcgg agtcggacat ggccgacggg aggcactccc cgccctgtgt gcgcaacacc 240 accggccaca cggggctgga actaccttta atgatggcca aggagaaacc tccgattacg 300 gtggttggag acgtgggcgg cagaatcgcc atcattgtgg atgatatcat agatgatgtg 360 ggagacttcg ttgccgctgc agagatcttg aaagagcgag gggcctataa gatttatatc 420 atggccacac atggtttgct gtctgcagac gcgccacgcc tcatagagga gtcggccatc 480 gatgaggtgg ttgtgaccaa caccgttccc cacgaagtcc agaagctcca gtgtcccaaa 540 atcaagacgg tggacgtcag catgatcctc gccgaggcca tccgccgcat ccacaacgga 600 gaatccatgg cctacttatt ccgcaacatc accgtggacg actaaaaggg agcgccagag 660 gaaaggccaa tgtttagtta atgccaggat tacatgtttg ctgtacacgt atccttgaca 720 gtttgaaaga aattcttcat ttttgccttc aaataatttg ttttcttaca gaaaacgtat 780 aaaatgtaca aaaaaaaaac cctccctgct gacctgagct gctgaaagga tgtgcaacac 840 atttacaata accggcatgg ttttgagcgt agaagacttt tggctaagtt cagaacaaac 900 aaacactcca aatcacaatc aacaggcttt agcagctcta catttgctgt tgaagaagcg 960 tccatcgcat gtcctcctgc acccagcttc acaacacaaa ccacacaacg gaccaacttt 1020 gtctctcaga agtctttatt tagcattttt tgcatcgttt ccggtcttgt ttaaaacagt 1080 catttttaaa agaggtttaa tacaataaaa cttgtttatt ttaggatctt ttcagtattt 1140 tgatgtagta aaacatcttt ttaaacattt ttcccactgt tactgtataa cttggtcaat 1200 ttggaagatt tatttagatg ttggacttaa tcctccgatt agaaagtttc tttagtctgt 1260 tatcttgatg agccaggaca catccggctt tatggttaaa aatgtcttcc gtgctaaaac 1320 actacaacac tgagccacag agtcgtttta aaagctgtga acgttcagtc tgcgatgccg 1380 cttcttcatc agctcagatc cacatttgtc caagacgcgt ttggctcgct tggtgtattt 1440 attacccccc agtttcccta ttttcatgac tgttcgagcc gtttgtcagt gtgaattcat 1500 taaaaacacc ttcctcaaca aaaaaaaaaa aaaaggccgc ctcggccact ctgcgttgat 1560 accactgc 1568 <210> 159 <211> 2040 <212> DNA <213> Oryzias javanicus <400> 159 tcagcttgga gcttccacag acacctctgg ctacctcttt tgaagggaag catggcagtg 60 ttcgatactg ggtaaaggca gaacttcaca ggccatggct cctgcccatg aagacaaaga 120 aagaatttac agtctttgag cacattgaca tcaacactcc aattttgctg tcaccacagg 180 cgggcacaaa agacaagaca ctttgctgtt ggttctgcac ctcaggtcct atttccctaa 240 gtgccaaaat tgaaaggaag ggatacacgc caggagagtc tatccagatc tttgctgaga 300 tagagaactg ctcatcccgc atggtggtcc caaaggcagc catctaccag acacagacct 360 tctatgccaa agggaaaatg aaggaggtca agcagctggt ggccaatttg agaggcgagt 420 ctctgtcgtc cggcaaaacg gagacctgga gcggaaaaat gctgaagatc ccgcctgtgt 480 cgccctccat cttggactgc agcattattc gagtggaata ctctctcatg gtgtacgtgg 540 acatccccgg agcgataaat ctgtctttga acctgcccct cgtcatcgga accatccctc 600 tccatccgtt tggctcccgc acctccagtg tgagcagcca gtgcagcatg agctggctgg 660 gtttgccaga gagacctgaa gcccccccaa gctatttgga aattgtgaca gaggagcaaa 720 ggcagagctg tcttgatgtt ccggcggttc gagaggagct taatgggcct ctgtttgcct 780 atattcatga gtttcgcttc cagcctcctc ctctgtactc cgaaattgat cccaacccag 840 atcatgccag tcgtacagaa gagcgcaggc ttgacgcctg tccatcccgc tgaggaggag 900 tcccgaaatt cccctcgact tatgcggggg tgaaaccgaa acagaacctg cctacttggc 960 tcaaatgttt ttctcagaaa acgttcacac agtgatgtcg agaccaagag agaaacaaat 1020 ccctcaacca acaaagactt gctcgcaggt gtgttggatt gaacaaatgt actcctgctt 1080 cccgcaacga gcggaacagg aagtctccag ttggggttat cgcctccttt atgtgtcagc 1140 cagccgaggc cccgggatgc ctacagatcc acacgctcgg cctgtatgct taaaatccca 1200 cacttctcgg caagagcttg gacatgttca cgaaggcgaa tgaccacgct cttctgaacc 1260 tgtggcacac aaggacgtgg cctctgacac gaagggtagg actgtccaga cttcagcaga 1320 attaccttta aaccaggatg aagaaaagag aagaaacaat gttttaacca ccacacagtc 1380 tgaaatgctg tcagcataag tcaccgacag agtaacaaaa aaaatagttc ggcttcattt 1440 gggattttgt tttgcacatt atatttacat agttgcgtgg ctctgtttga caaggttttt 1500 cttgaaatca ctcgtagtta aagtttggtc tggctttgta aagcagcaac ctaatactag 1560 actgcaggct ttaacctttg agactgtcat gggcggaact tcaagcgatg ctggagaacc 1620 gaatatgact cttgaaaaca aagaactaga cagttcaaga agaatgcact gagctttttt 1680 ttttcttcgt gtttatcctt ttttccgttt gtaacgtaga aaccgacgac taacttaatg 1740 cctaacgcag gacactattc atattgaagc tctttcggtg tgtcgcctcc taaagcttgg 1800 atctgtgtag ccttcttcct tttgtgtttg atagcagctc tgtttcagtt taaatccagt 1860 cgtagaatag cttcagcctg tgttctgatg agatttgctc tgcgtccgga ttggagaggc 1920 tgcagtatct tttaaaacga cacgtcacag gaactgttag gagtgtgaga caaaaaaaaa 1980 ccctgcaacc tctcctctcc ttatctcaga gctaaaggtt tgcattactg cccaaaataa 2040 2040 <210> 160 <211> 1454 <212> DNA <213> Oryzias javanicus <400> 160 gggatcctct agggcagaca ttcgctgtga ttccttatca accaccaaag gctctgttgc 60 tgacagtcct ttcccatatt ctgaccatga agctctcact gctgagctga agctggactc 120 ttgtgtctca gccgagactg gaaatgatga agcattcaag acgccggagt cctctccagg 180 gaacctggct gagttggttg acattgtgac cgaggcccgc actgaagtca aagtgggctt 240 gcactgtgcc gagcggatgc gctacactgc agctcgtaca ggggtgatgg ggctggccct 300 gctgttcttg gagctgctca tcgctgcggt tccctggttc gctctgggag ccgaacagcc 360 cttcccacaa acctccttct acctgctggc agcgctgtgt ttcgccattc tactgaccac 420 atcgctgctc tatatctttt acacaatcga gatcaaatct ctccagggag ctgaagacca 480 gatgaggctg gcggtgggta gtctgcatga aaagctcagg ggttttcctg tgactcagcc 540 tcagagctcc tcccagaggt catcagaggg tcaggagccc cctgccttag acccagagga 600 ataatttcaa aataaaatta cttttttccc tactactaaa tttaatgctg agaaaaaaaa 660 gtgagacatt tctgaaagta gtacatgacg catgcgtcaa catttttata cttttaatca 720 tttgtaggat acaggtattc tccttagcac ctgctgctcc cacatatgcc tccttgcaca 780 tattttacac ctgcatggtg atgctgagct ttaaggcatt catgtgaatg tttgtgtttt 840 taaacttcag gtcggagttg cattccacca atctgcacgg gaccatttgt taaaatgttt 900 tccatgtcat gctttctgtt gttacattta aaaaagcaca gttagtgatt aaatactaac 960 agaaaaatct ttacctgtat ctcactccga atgatgaaga gtttacattt caggttagtt 1020 acaaggcgag aagactgatc ttaaacccgg ccgggttgtt tgcagctaaa tccaagagga 1080 aagagcaaaa tctttgtatg ttctgtacgc tcgacctctt ctaccgaaga ttatgttgga 1140 gataagctac actcctctaa acatccatgt atgtcctgac tatgcaatag agaatgttca 1200 atgcagtgac ttgattgtaa aatgtgtttt aaagatcagt tctttaaaat cttaagtgta 1260 gatcaacccc catgaactcc tttattatca tacaaataaa atgctatgat ttcttatttt 1320 tatcatgctg tgtaattgtg ttatgaagtc ggtagttctt ggttaaaata gctttccaat 1380 taaatgaatt ccaaatagaa actgtgatgc aaattatatt taaaagcaat aaaaaccttt 1440 tccatgacta gaag 1454 <210> 161 <211> 2040 <212> DNA <213> Oryzias javanicus <400> 161 ggtatcaacg cagagtggcc attacgccgg ggaactattc caacatcttc caccgtcggc 60 taccttgcac ctctccaaca tcccccctct gtggttgaag atgatctgaa gatgctgttt 120 tccagttcag gagctgtggt taaagccttc aagttctttc agaaggacca taagatggct 180 ctgatccaga tgggctctgt ggaggaggcc atcgagtgcc tcatccagct ccacaaccac 240 gacctgggtg agaaccacca cctgcgggtc tccttctcca agtcgtctat ctgagccttc 300 gacccgctgg tcagaccccg gtcagggagg ggaccggacg gcgcccacta cactccgatc 360 attccaacaa gcgtctgcag aaactaccat gaagtccgat gtaaccttaa attattgttt 420 ttaaattaat tgattcttca ctttcagagg tcaggtattt gttagaaaat tccgaggttt 480 tcctctgaag tccggatctg gagcaatcca ggttttttta tttttaggat ttttcaaaat 540 gtagccagaa gattgttaga ttacactcgc aagtcagtct caaccttgct ttaaacattt 600 ttttccccac tttcttgcct tttgatctta aaacccagac tcttggggtc tgctgaccac 660 ggctcccact caaatcttaa aattctgatg tcacaaatga atctgagatt gttcctgatc 720 ctcctgctgt agcgttcccc tgttcaggaa gccgtggcgt tatcaaagga cccccgtgcc 780 ttaattctga agtcacagtg acttcctctt taacagaaag cctctgtgaa ttggcaggtt 840 tacagttggt aaaggtttac tgtagagatg tattacagat atatccatat tttaagtgta 900 ttttattggt ggtgttgtca gtgcttggtt agtgtttttg tactgctggt catagagtga 960 aacacgtgaa ctgttttaga gggtttgctg gatttttagc cgtagaagtt gattattttt 1020 cctttttgaa cttctttttt tccacttatg caatcatgtt tttatcattt atcttagcat 1080 tattttaatc attcctacat tttttttttc tttcctttct tgctttggca gttttctcgg 1140 agaaacgcca ctgaatgtgt cgttagctcg tctgtcgcct tgaaacggtt attatttata 1200 cgtttgtgat ccactacagc tgaaaccaaa aacggccttc tagatgcaaa caaatctgcc 1260 tgcctcaggt ttctggtcta gcggaccagg aaaaaggatt tgtggactgg ttcaggctcc 1320 tgtgggaatg tttagcgatt tctcgactgg atccagccca ccggtgcaac ttcagtttga 1380 aaaggaaaaa aaacgaagag agtatgtgga gtgccttcaa agcagcactg agttgtagat 1440 cagacatgca ttcctctttg tttggacgcg tttggaagca ctcggaataa aaccagaaga 1500 cactggtttg gttcgttaaa tagttgttat tacgccgaca ttccagcccc tcagagatcc 1560 tccccgcctt caaaactcga gattctacag cgagggggac gctttcctct gactgaactg 1620 ctgattctgc agccatgatg ctttcagggc acctgggaaa tgtttcaaaa taaagtgcag 1680 atgtcattag aacttaaata tggtttttaa gtttggagca acaaatcaga tccaacataa 1740 ctgcattcca cagattaaaa atcaagcata cacccacaga ttaaaccaca aaaattgtta 1800 cgtattggct aaccgtgatg tttgttaagc catcgtcctc agttcataat gagaactatg 1860 aaagttggct tgggttacaa tttagatgag gacagaccag cagaattgat ttgataaatg 1920 ttacatttct gtgtgattgt tcttcagcag atcagttcaa gttcctatcg gttctcgacc 1980 atccatcgcc tgatatttga agctactgac tggatgcctt cctgcatcca ctctgtttct 2040 2040 <210> 162 <211> 1371 <212> DNA <213> Oryzias javanicus <400> 162 aagcagtggt atcaacgcag agtggccatt acggccgggg gacagtgaag attatcctct 60 cttctctgcc accctcacca tgttggtcct gcagatgttg actgttctct ccttcactgt 120 tgtcttcctg gcatctgtgg aagctaaagg cgtgcagatg cagagggacg tccagtgctg 180 catgctgtac tcccagggca aggtgcgtac caaagatgtg ctgcggtttg aggtgcagac 240 ggaggggccc gactgcagta tacaagccat cattttttac acaaagaagg cggtgaaatg 300 cgccgacccc agagatcgca aggtgaaaag gttgttgagg aaactcctgc agaggcaaag 360 aaccaaagct caccgaaacc cgtggttctt ccgccatgag aacctgcccg tcatgtcaga 420 ggacaagaag gataactggg ccatcctgaa tgtggagtga tgaagcaaca tgaggtccgc 480 aggaaaactc gtagtcatac gccaagtaaa tgttcagctg ctcgttgtct tgacttgaca 540 acacttgctg actctccagt cgtcttgtgt ctctctttct accccgtctg tccctctgga 600 acaagacctg ggcagcaata catacatcac tggctttata tattccacca cgaactgctc 660 ctgaaacact cgccggggtg tttttttgtc ggactgatcc ttctaaaaaa tggcttatac 720 tgttatttgt cgaagtctgc ctgaaagcgt cgccctccac gacggtgtaa ccatggcgac 780 tgatgtgaaa tcagtgaaat ggtgtcctga aaaacaaaaa agcgttgaca ttcatatagt 840 atatcagcga gaatctctgt gcttacttgt gacttgtata acttaattat gtaataagac 900 atcacagtac agtaaagtag atttgtcaca tcgagtttgc agaacatctg ggagaacatc 960 acacctataa agctgttttc ccttttagat agtggtgata ttagaagtct cgttcgggct 1020 atatctaact gtatgtggat taaaaaaggg accagagtga aggtttctat gtgggttcac 1080 tctagttttt aacacagcaa agaaaggttc ctatatcttt tgtgcgttgt ccatacaaca 1140 acttgacttt ttaaattcga cctttcaacg tgaatgcttg acgtaaaaat ccatttgtgg 1200 tttggattta aaatgcttgt ccgtcaccaa actatgccaa agtattcatg agtccattct 1260 tcaaatgaca aggctgttat tcttcgaggg ctctggtgtg tttcacacac acacattgta 1320 ttgtagaaga atgcaatgta tttcaagtaa aatattttat aaatttatct g 1371 <210> 163 <211> 1336 <212> DNA <213> Oryzias javanicus <400> 163 gctggaaaga cgctcatgag gtctccagag cccaaacctc ccagcccgcc cacagagcgc 60 ctaatccaga tttggaagtg ctgagccagc acgtatccag aaacaacaag aagctctgct 120 cagaaggagc cgggtccagc agaactccct ccgagtccgg ggcagcttgg cgcctctcca 180 gggcccgaat ctgctgctgc tgccttggag tcaagtttca tgcagtggag taacggatgc 240 ctttgtagtt tgggttgtca aggctctgaa cacgaccaca gcatgacgtc ggacatctac 300 cacctcccgc tcaacgtgta cgtcatcgtg ctgggcatcg gcctcttcgt cttcatgctc 360 agcctcatct tctgctgcta ccttttcagg ttgaaacaac aaggaacgag ggagcagttc 420 agctacaacg aggtggtgct gaagggagcc agcaagaaac tgagtcttct tggacaaacg 480 tgcgcggtgt gcctggaaga gttcaggact cgggatgagc tgggagtgtg tccgtgctca 540 cacgcatttc acaagaagtg cctgctcaaa tggctggaga tccgcagcgt gtgtcccatg 600 tgcaacaagc ccatcctgcg gctccacacc gacgccccgc aggacgccga gggtccgatg 660 gaccccgagg aggtgtgagg ttgcagggcg aacacaagac aaccccccct tccagaaaca 720 cacgcatcga acacactaaa gatgacgaac agtgatcgtc tgacaggaaa agttgatcct 780 gggaggcgcc gccctcgacc ttcgacagga acaggagtcg ccgtgattca gagggaggcg 840 gaggaggtta gagcgtagga tctttcatca aaatgttcct tgttgtactt tcatgttgca 900 cagttcacca gagaaatgaa aagagacgat agaggccgcc agcgagccgg tgcagcactg 960 ccacagacat cacggaggcg ccgaggagcc cagaccatga ccaacctcca cgatctcagg 1020 ggtgttacca gaacagccag cacaaacccc gatgacaaca acgcatccgc ccgtgccacg 1080 catgcatctt cagtactgcc aacgcttcgg cagccagggg gcgccaccac ttcaggctga 1140 aacagaccag ctggaagacg aacttctaag tagacgatgt tgtttccgat tgtgtccccg 1200 cccctttacc tttctcaaaa aactaaaaca aaagactgac tgatagaaaa ctagtctttg 1260 ctctgtgtac tgtacgtaaa cgtctcccta tatattgtta ttttgtattt taaataaagt 1320 gtcatgtcat gtgtta 1336 <210> 164 <211> 1302 <212> DNA <213> Oryzias javanicus <400> 164 aagcagtggt atcaacgcag agtggccatt acggccgggg aatgtttgta aattgtcggc 60 ttagatgcac tactgtttgg atctcagcgc gcaaatgtat ttgtcaatgt ttataaactc 120 ttccattttg aattttgttt aaaaaattac cggactacgc cgtcggcggg ccgaaaattc 180 tcatcgagga ttcggatagt aacgtattga cgaaggcaag aacggagttt agaatggtcc 240 tcagtcagat ggacgccggt aaagcgctga cggcggcggc agccaaaggg aatgccagcg 300 aggtgcagcg gatcctggag gaatgcaggg tgcatcccga tacccggaat gagtttggca 360 ggacggcgct gcaggtaatg atgatgggga actccaaaat agcaggcttg ttgctggaga 420 aaggagccga tcccaacgtc caggacaaac acggcatagc gcctgtccac gacgcagcga 480 ggacggggtt tctggacacc ttgcaggtcc tggtggagaa cggcgcttca gtgaacatcc 540 ccgaccagaa cggcgccctg cccatccaca tcgccatctg ggaaggccac cgcgacgtcg 600 tgcagttcct ggctccgcgt tccgacttga agcatgccaa ccagagcggt cagacggcca 660 tagatgtagc ccgagcttca tgtgtgccac atatgatgga ctcactgttt gctcatatac 720 atagttagtt agaaaggttt tcttctcacc cctcattctt cttcttttgg cttcaaacct 780 cgtgacttga actcattgct gtgtaaaaga ttattttttt gtttttggtg gctcagcatt 840 aatatgtgac acaggacata ttgtcttggc agcttatttt cagtggatgg gtgtctatat 900 actgtagata cctcttttgc acagtgcaat ttaggcacct tatacttatg aatatatctg 960 tttccctttt aactgggagt gcacatttgt ataaagtttc cccagtgttt cctgattatt 1020 tgtgtaagaa tttgagcagt tcatacacgt gtgtttcttt ttaaattaca aaacttgaca 1080 tggtgcaccc tcgttgcttt gcatagttgt tgacctgaat tagatgtact tagactttaa 1140 attgattctt atttatttgt tggactgaat attttctgtg actttgtaaa tacaaacata 1200 ttgtgatttg tttaaatgtt atttatataa aaacttttac gaaaaagtga gattattcac 1260 tttaatattt gacgaaaaaa aataaaattg ttgaacttag gg 1302 <210> 165 <211> 1299 <212> DNA <213> Oryzias javanicus <400> 165 agttcctgaa aagagaggca tgttcagtgt cttctatgac ctggatcctc agggaaagaa 60 cgctgtactg atgtccgtca tttctggtga tgccgttgcc gctgtccggg acatggcgga 120 gaaggacgtg gtcaatgagt gcatgaaggt tttgcgagaa ctcttcaaag agcaggaggt 180 tccagagcct gtaaattatt ttgtcacgca ttggagcaaa gacgtctggt cccagatgtc 240 ctacagcttt gttaagaccg gaggcagtgg agaggcctac gatattctgg ctgaagatgt 300 gcagggtaaa gtcttctttg ctggagaggc caccaaccga cacttccctc agactgtcac 360 aggggcctac ctcagcggag tccgagaagc cagcaagatg actgccgtat aagctgacga 420 agctctcaca aacaccagca cggatttacg ggtcacacag accaacacac tgcaaaccag 480 ctggtactac tttacccaaa ctgtttcatt agcagctgct gtagtagctg atcaggaaaa 540 tactggcaga ctctttctgc agcagaatcc agcagggttt ctacttaatg aacatgaaga 600 acttgaagtg cattttcctt ggaacaaagt tcatcaggta aactttacac gtgcagcttt 660 gtctggtcag gtcattttgc cgaaaaatca aggcgctttt tgtcaaataa atttatattt 720 gtaatactca aatgtgtgat gaaacttcaa ctttttagga tgcacgagta gtttgtaagc 780 acctaatcat agttgtgaat cgtctacata tgcataggtt tgattagaaa gtgtgatcat 840 gaagattttt tttctcagtt attgaccaaa gttgacgtca tatagaagtg tacctttttg 900 ggtttaatgt gttgggctag tagtgaatgc tgatgcaata agagaagata gggtacagct 960 aaagtagcac ttttcattta ggacaacaaa aaaaagataa taaagtacca gaaaaacact 1020 aggtagtaga aatacaaata gttttgcaaa agtgaaccaa accaaacaac tatttagaga 1080 agggaaatgc tttcttttaa tttataaaag ttatgggatt tgcagttgag caaaagcata 1140 accaattttt tcactttttg tggttacttt taattgaggc gtaatgtttg tttttgtctt 1200 tgttaatacg tttacatggc tctgttttgt tagggtgatg ctgtgtattt atcagaagtg 1260 agtgtgtatg tgtgtaataa actgagctgt taactgccg 1299 <210> 166 <211> 1223 <212> DNA <213> Oryzias javanicus <400> 166 aagcagtggt atcaacgcag agtggccatt acggccgggg ttccccgctc agaaggtaga 60 cagcaggcgc cctcactgga gggtgtgtgt gggggggtaa aagcgtaaat tctgccccgt 120 tttcaacaag tagaaggtgc aaacgagggg gaaaaagatg gagaggaagc aaggagaggt 180 ggaccacctg gagcgcccga gccccctgac cgacaaggag agggtgatga tccaggactc 240 gtgggggaaa gtctaccaga actgtgatga tgccggagtt gccatactag tcaggttgtt 300 tgtgaacttt ccctcatcca agcagtactt cagccagttc aagcatatcg aggatgcaga 360 ggagctggag aaaagctccc agctcaggaa acacgctcac agagtcatga atgccatcaa 420 tacgttggtg gagagcctgg acaacccaga caaggtgtcc tcagtgctga agtcactggg 480 aaaggcccat gcagtacgac acaaagtgga ccccgtgtac ttcaagattc tgagtggcgt 540 gattctggaa gtcctgggag aagcgtatcc acaggtgatg acggcagaag tggcctcagc 600 gtggaccaat ctgctggcca tactttgctg cagcatcaac gccgtctatg aggaactggg 660 ctggccgcac ctctccacct ctaccggctg aggcatctta caggaggctt ttcaaaactc 720 cctgctacct atgaactagt cagcaatcga ctgactctaa tcttggaatc cagttccgta 780 taatctatga taatcatgga gtctgaaaaa tgtacgcagc ataatcaaca gtgagaacaa 840 atactgcgcc atttttacgg ctagcagtat gttcatgagg agggatcttt aaatttatac 900 tgttataaac aggtgacact tttaaagggt agaacaaaga gtaggaacat gcatggaccc 960 aatcaatttt taagaagtca catttgacct gagtgtgcct tccactgaat gtttatatct 1020 agagaataaa atgtaaacag cattctttct aaagattcaa atgtttttca gatgtatttt 1080 gctcattcat ttgaattcac tcatgtccaa acaaacgttt ataccgtttt ttttctttgt 1140 atctgttgtt tttcttttgc atttgtattt acaatcaaat gtagatggga ataagtgggc 1200 aaaaaataaa cctggttttt gat 1223 <210> 167 <211> 1186 <212> DNA <213> Oryzias javanicus <400> 167 aagcagtggt atcaacgcag agtggccatt acggccgggg gttttctgtt ttgctgctgc 60 taactgcgat tgcagacccg actataattt gtcacgcaga taaaataaag acacgccggg 120 ctcccggagc acttcaataa acatttaaaa atacttttat ctgttacaag ttgggtgata 180 aaatgggacg catctttctg gatcatattg gtggaagtcg cctcttttcc tgcggcacct 240 gtgacaccgt cctgaccaac cgggctgaac tcatctcaac gcgcttcact ggagccaccg 300 gcagagcttt tctgtttaac aaggttgtga atctacaaca cagcgaaatc caagacagag 360 tcatgcttac agggagacac atggtgcggg acgtcagctg caagaactgc aacagcaagc 420 tgggttggat gtacgagttt gccacagagg aaagccagcg ctacaaagag ggccgggtca 480 ttctggagcg ggcgctggtg aaggagagcg aaggcttcga aaacgttcac tctgacagct 540 cctgactgct ttcatttctt cagtgttcct ttcatgagta gagccacacc agagatgtgt 600 tactggctga agttcaaacc gagagctgac gactactgat gcttttctgt tgctttgaaa 660 acacctgcag tttcagtatg ttcccaacag gttgtgctgt tgttccggtt tgtttgggtc 720 tgctgttcag agctcagaaa gtgtctccag tgctaaactg attcagatgt ctggtttggc 780 aaagtaacat ctaattactt gaagatgaat atcatagtat tacactacaa aaatatttgg 840 taaaatgctt cattgggatc tttccttaaa tgctgcagag ctttttattt tagtgtgcca 900 aatattttca acatgacaga aattatatta tatgttgaaa tatatgttat ttagtttcca 960 agcagtattt tggggctttg aagaatttac ttactttata tttatttata ataaaggttc 1020 ataaaacaaa taaaagcatg ttttggtttt attaagggca acatttatta ttcagttcat 1080 tgaatatgtt cctgatgtct ttttttccta ctttatttaa tatgtttatt atttttattt 1140 accttaattt tagatgctta aaatgtatat ttcttttttt ctatgt 1186 <210> 168 <211> 1107 <212> DNA <213> Oryzias javanicus <400> 168 ccatgggctt gagatcaaca ctgagaagcc ttctgctttt catttggatt tcagaacaat 60 gggcagagat gaccacagat aactgcacca actaccgtct gcagtttgag cgggttttct 120 ctgttcctgg agatgtggcc atgctgaaca gcaccctggt gtctccggac gtgttcgacc 180 acaaaaccgt gccgtacaac atcacatggt ggaacttgaa aacaggacaa gagatgatca 240 accagacgga caaagtcttt gttctgaggg agaccatgtg ggttcttaat gtaacatggg 300 aggacgacgg ggaatatatg accatactga gaactccgtc tcactgttac atgcaatcca 360 ctaagctggt ggtggagatg ccagactctg gggtgtgtgg gaggccacgg aaagcctatc 420 aagagcttgc aataggagta gcagacacac tgaactgccc cctgatggtg tacatcaaga 480 aactgcacag ctacaacatc tcctcttcaa tcagttggtt caaaggttgt gaccccgtag 540 ctgatggaac agacaagtac tcctaccggg gtcagaccct gctctccttt gacatggttg 600 attccgatga tgatggctgc tacacctgca ctctgacttt ctccctcggg ggttttagag 660 gatcggtgtc ggagaccatt gtagccccag tcatagatga tacctctttt ggtcctcagg 720 tgcatcaacc agcaaatgag atcatcaaag cagagaaagg gtccaatttt accaaaaagc 780 gcctggtgtt tgtgccaggt cctgggatgt cctttgttga tgtcacttgg tcggctggaa 840 aagactttat tctcaataca gaaccctctg agcgtatcta cacatccgga cagcgcatct 900 ggacccaaga tgatcccaaa gggttttggt ttgagacgca tctctctttc actgaattaa 960 gaagtgaaga ttttaacaca aactacacct gcagagcgca cagtttcaga ggcaatcccg 1020 aagccttttt cactttggtg ccaacagatc caaacatcat cctccatcga tgtgttctcg 1080 gtgtgtcatg cttctcttca ttgccac 1107 <210> 169 <211> 1060 <212> DNA <213> Oryzias javanicus <400> 169 aagcagtggt atcaacgcag agtggccatt acggccgggg gttgcaaact gtcaacattg 60 acttgtcgtc atctccgagt cactcctcga gactaattca ctcagcatct gtggaagcta 120 agctgattag gatgaaggtt gtcggatcta cctgcgctct gaagaccaag gtcagcggag 180 agatcggcct gtccgaccag agcctggcca tctccaaatg caagctcccg ctgctggacg 240 agcagatgag cgtcttcctg caggacatga acagctgcta cagcaagctg aaggagctcg 300 tcccgacgct gcccacgaac aagaaggcca gcaaggtgga aatcttgcag cacgtcattg 360 actacatctg ggacctgcag atcaagttgg acgagccgga gaagagccgt cagcagtcct 420 cggggagcgt ccagcgcacg ccgctgacca cactgaacgc agagctggcg agcatctcag 480 tggagaatgg ctgctcagac gagagaatca tgtgccgtta agggtccacg gagcccctcc 540 acccccccac ccacccccaa tcattccaga gcggacaaga caacctgatg cagcggccag 600 agcacatcgg catcaagagt cttgaactgt gaggggacgt ttgaaactcc ctcagctaga 660 gaaatgtaat aaaatcatcg aaggggacat tcttcaagag tgacggggtc tcgattcatc 720 cgagcgctcc gaagctagag gaccggcgca gggtccagaa atagagactg ggttaatcgt 780 gggaccaaga cgagatcaga gcaaccagct tgttgctcgc agtttcataa tgactttgtt 840 acgccctttg tatttttgtg taaatcaaat ggagagttct gtaaagtaat ttctcaggtt 900 cctgagcgac aaaactgtat tgtatattac aatgccacaa tatgtgaaga tattgttttc 960 ttacaatgta ccttatttgt gtttttatta aaacaagact tatttttgaa acaaaaaaaa 1020 aaaaggccgc ctcggccact ctgcgttgat accactgctt 1060 <210> 170 <211> 1046 <212> DNA <213> Oryzias javanicus <400> 170 ggcgatgaga gatatgtctt cccaaagtct tagagacagc cttcgggatc tggtttcaca 60 agactcgact ttaccgaagt ctgcggctgc acgctacgac aacttttcaa aaaccataat 120 ggcgtctatt aacgagagac gggagctgga ggagcgagaa aggatgctcc gtctccaaac 180 cgacccccgg cgcactactg cgccgacgct gggatttacg acatccccag caagaggagt 240 ctggcaccag acaacgctcg gcctccaggt tcccgcggcc caacgccccc agcttatggc 300 tccagggagt ttctgatgag cacaggcatt ctggggtacg gcatgaggac ctcccctctc 360 tctaactcct ccacgctgtc tttgacgcac gcttccaaag cctccagctc acctctgcag 420 aactgtagca gcagcagtct gcaaaacaag ggcaggtctt cctctcccgc ctactgtcct 480 tccgagaggc ccaccccttc ctcgacgtcc accttacctc gtttgacgac cgccaactcc 540 tccgcccctc cttacacctc ctatgccacg gcgaaacgct cctcgctgcc gttcccgtcc 600 gaagggaagg agtctgtcac cttgggagct ctgaaataaa acttcctcca tgtctctgat 660 ggtgtgaatg aatcatctat gcagtgttag cctctgtttt tgcagctcca aaatcctgtg 720 taaacgagag gccgtttgga gtttccccgt gtgggaggat gtgtggaaaa caaacacaaa 780 gtgaagaatg aacttggtaa caggactgca aatatgcttg caaattcaaa aaaagcaaat 840 ctcaggatat cagtgcctcc tcttacagac agagggagca cttcaaatgg aggagaagag 900 ctacctatgt ggagattgca cctcactatg accaggttgt gtttcaaaca atgtatttcc 960 ttttcagaat tgcatcatgc agaaaaaata tcttgtttag taggattttt tgtagctgtt 1020 tatatgaaat aaacttattt tgcaaa 1046 <210> 171 <211> 2040 <212> DNA <213> Oryzias javanicus <400> 171 agaggctggc cttcaagctg gagcaggtgg tggccttcat gagcgtggag agctgaggac 60 cgcatttccc aggatgcact gggaagagac cccatcagaa accgagccgt gcctgagcaa 120 agacctgtcc ccatcttttt catcatgtga cttcctcccc tcagcttttt agagacttct 180 tcctttaccc tttttctgct tcctctttga agagactttt ctcccctcat tcactctgct 240 gcaaagactc gtttacctga atacgtgagg ggtggtctgc agctaaggtt ggtgtctccc 300 accgtgcaaa gtggggcatc gctcagcttc accacaggga gtgattgctt gagaagctgg 360 ccatattggc attcttcatt ccccagctgg aagagagaag aaacattttt atgttgcctt 420 caagaattta cacagtaatt tttgaaaacc acaacgttgg gtgtccattt gttgaacttt 480 agagttagta gttgagatga aaatagtttc caagcgtttg gttttcagta gtgctgtttc 540 caacacgagg aattcaagcg gaaagtgatg actgcaagcc aaatgaacac ctttggggga 600 aattaatagc aagaatggtt tgccaagttt acactgtacc ttcaagcaaa gcatacatat 660 cagtgaaatc tggggagaat ccaggcaaat ccagaatgtt ctttaaatgt agctggaatt 720 gtatttcaga aagagactga tcggggtagt taatgattct tgctcttctc gatgtttcct 780 ttgatgacag acaaaaactt tagaatgcag tgcatcccca acttgtagcc tgttgcaact 840 ttcaaacatt ttacttagcg tatgatcaag atcattttta atgagttgcg cttccatggc 900 tactgcaaac gtaagcaatt agaaaaccca ggagtcccac ccaagttgga tcttctatta 960 aaaacaaaat ttaaaaaaag cacacaacca acgcaggaag gcagctcttg ccaactttgt 1020 cgtctctgca acagtatagc aaagcacaca cgcacagata aagaatcaac agctcaccag 1080 ataaccgttg aaaactgttt cgactgcggt ctcttccaaa tgtttcgttg cctctgtgaa 1140 ggtctgtcaa agcacacacg cacaaattta caacaacaac aaaaaaagaa tcttcagctg 1200 cacaagatct caactgccca cattgccaca ccaaccagag gtggtcgaca gggaagagct 1260 ggaaacaaaa caaagtcaga catggctacc taaagaggcc cagttgtgtg agaaacacct 1320 cttttccagg acgttcttat tttaagatgt gtgtgtatgt gtgtttggag aaatctaatg 1380 agatggactc agctggtcag ccaaaaacca aaggatctta aaattgtcaa aacagttcaa 1440 atgtatttat aaagtgccac tgaggaatta acaaaaaaag gactatgtat aagaccacca 1500 cttctcggac aaaaaaacaa catattgtga ctgatacttt aagaagcctg cgtgattttc 1560 tctgacctca gtgtgtcgaa gtgggaggct ctgtgggcga tttgatgtga tcctccatgc 1620 tatttccatc gtcctgggtc tctccggctc tcggcacacc atccaccctt ttgtctggct 1680 cttgacttac caatttatct gctttgcaca agccttggag atggtagcta gttgcataca 1740 acaaacccca actcctgagt gtgtaattgt tgaggcactc ttgtctgtat tagtgtagat 1800 gtcctcagtg gaagctgtgg gcgccctttt gcaagcctca aagaaaagag aaaaaaaatg 1860 attaagcatg gcagctagta agcataatgg acattaagag taatggagac ttattggatg 1920 tgaaccccca ccacgggaaa gagcgactga aagatgatgg aggcgccctc cgtacctttt 1980 gacctctgcc ctttcttttg ccttgacaac gtgccccatg tggtgatgtg aatgtgtgaa 2040 2040 <210> 172 <211> 1028 <212> DNA <213> Oryzias javanicus <400> 172 gcaccgctta cacccgcagc aggctctgga gctcgagaaa gaatttcact tcaaccgcta 60 cctgacccgg cggaggcggg tggagattgc gcacacgatg tgtctatccg agcgccaggt 120 caagatctgg tttcagaatc ggaggatgaa atggaaaaag gagcacaagc ttccaaacac 180 caagatccgc tcgtccagct cggcctcggc ctccgggccc cagcagcagc agcagcagat 240 caaaacaggc cagcagctcg tccccacgcc gtgcactgtg ggtctatagt ggatgaaccc 300 ccaaaggaaa aaataaaaat cccagactga gatggcaaac aacacgggtg gagtttgatg 360 gaccgatctt cagtatttta cactcttggt gttatctttg tcagcctctg ccattgggcc 420 catttcacgt cttttgtacc ccttccccaa acggtcgccc tcttcatata agcttgaaac 480 acattttaat tgccacggtg gcaactgaag tctttatata tttgtttata atgaaagaat 540 tcaacgcaca ttcaactaga tctgtaggtg tttcattgga atgagagcaa agtaagtttc 600 agctcatttt tctatgttga ttttgttctg tttttatata ttttttgaat acttttgctc 660 acagaaagtt caaatatact tgaaagttat tatagcgaga tgtctgcctc ggaggcgact 720 ttagaggcgg ggtgtagttt gtgtgtttga gtgggtcggt tttactgttg aatgtaagtg 780 actttcacat cagatgtaca tagacaaatc ctacctaatg aaggcacaat aaggaaaagc 840 gtttcgttca ctccgttggt gtcgtgaggt ccagttttca tttgtgctcg tgcgtccttt 900 tgttgtgctg tgttctaaaa ctgtgaatac gtgtacgtgt cgtctcagta aatggctgtt 960 gcaatgtagg cttatagcgt ataggtttaa ccctgttctg atgaaataaa tacgtgatca 1020 aggctaag 1028 <210> 173 <211> 1025 <212> DNA <213> Oryzias javanicus <400> 173 ggctctctgc ccgcgcagct gtcccccgcc tgctgggagg attccactgt cctgtttgct 60 ccaagttcat ggcaacagat gaaatggaga agcacctgct catgtgtttc agcaagacac 120 gcctcaccta caacaaggac atcctgtcca gagactctgg ggaatgtacc atctgtttgg 180 aggagctgga gcagggagac accatcgcca ggcttccatg cctttgcatc taccacaaag 240 ggtgcataga tgaatggttc caggtgaacc gctcgtgtcc agaacatcct gctgaataga 300 agctgcaaac cttcaccttt aacctttgac acgtcaaagc cgactttgtg ccctgttcgg 360 atcctaacac tgttccagct gagcatcagc attcctcagg gattattaaa gacaattttt 420 tatattccct cacagagaag cagtgaactt tggagatgtt cctgcgtgga ctgtgacttt 480 caaagacaca aaggtggagt tgtagatgtg aatgtcgcct ttcagcctca gatgaatgca 540 gcctggagtc tgatccaaac agttatgaag acctgggttt attgcagagg gcttgtatat 600 ccaaaatggt gaacgcaggt ttgggctaag tgagtgctga gagacttgat caggtggctg 660 attttgtgca atatgaaaga cagccaaact gaaattaaat cattcttgat cagctttaag 720 gagtgaatgc agtgtttgat gatagtcctg gagccactgt tgtttgtgta acaatcatgt 780 gtcctacaaa agatcttgga ttttattaat catgtgtcca tttcaaacca cagaaatgtg 840 attgtgtagc ttaaaggaga aattaaaaaa tgtatctaat gatgattgaa ctctctttag 900 gagtgccata atgtgctgct atgttaaaga ctggaaagtt ttccgataac ctttgaacca 960 tgttgttcgt tctttctgtt tgtactgtaa tgaattgcac aacaataaat ttttttatct 1020 tcgta 1025 <210> 174 <211> 1022 <212> DNA <213> Oryzias javanicus <400> 174 gacttaaaaa aacttttatt gtaaaaagca aacagatttc cggagcgtcc gtccggaccg 60 gagtgcatga atgtcagttt gatggagggg gcggggcttc tgcagcagcc aggtgaacaa 120 agacagccag tggagaagtt ctatcccgtt aacaccttca ggagattacg cgctgctgtc 180 cgagcatcag ggctgagctc gtactctgag ctaatccagc agagacggga ttacatgatc 240 tggaggaaag gaggtcagac gggggaacag atgtgtcgtc gtggttacgg gaaagtttca 300 ggaggagaag aagcctcagg aggtcgcgag gggtcagcaa acgcagcagc ttccagagaa 360 cgtttgagcg aagtgacccc gtgacctccc tgacatcatc agacgggctt ctgtgagggt 420 ccgacgccgc ttcacggtcc ccgtcagacc agaggaggag gtcggcggcg ctcctacacg 480 gccagcatct ctcgctccgg cttcttcctg ggacgttccc gctctcctgt ccgctccgga 540 ctttctggca gctcctccga aggaacgtct ggaagctcca cgtctccctg agtgatggcc 600 tccagctcgg ccagaacggc gtcctcgtcc tcctgagtca gagagccggc gagcatctcg 660 tcgatttgcc gctggtactc cacggcgtcc tgggtctcat ccatgatccg ctccacctct 720 tcaatggaca tcacctcgtg catcttcttc agacactcgt tcccgacctt cagcccgtcc 780 agaactttct tctcgatctg agcgaactcc agatcctgaa ccatccgctc caggttcccg 840 atctggttct ccgtcttgtc caggagctgg tcctggtacc gcttcttctt cagcaggagg 900 agagctttgt ccttcttgcc gtcgtggagc agcttcttgg ccagcagccg ctccttgtcc 960 agctgcaggt ggatcttctt ctggtactgc ctcagcttat ctcgctgctg cttcagttgc 1020 ag 1022 <210> 175 <211> 1014 <212> DNA <213> Oryzias javanicus <400> 175 atgtaggttc agtgtgcgcg gaagacgctc tcatctggtg cccatcttca acgtgtgcgc 60 ttttcccaac caacagctga tttatggaga ctctttatat agtaacgata tatcgagaca 120 cagtggcaca cttctcctgc aatcatacat cacaggttta tctcccccag agtgcacttt 180 ggctctgaga gctacaagtc aacacattta cactcctata taagcaggtc gggccagcgc 240 tgccttcaac tctgttttcc cttcacagac atttctatag cggcaactat aaataacagg 300 atgaataagc tgctggtcct ttctgtgctt gttgcacttc ttgctcttag tgctgaaagt 360 tttcgagtcc ccagacagac tgaggaggaa gagggttctt ttactaaaat gacaggcaag 420 atcaagtcct actacagcag tgctgtcgac accgtcaccg gatatgtgga cagcatcaaa 480 ggcctgaagc tggaggagaa agcaaagaat ctttactcgg acacaaccaa catcgtgagc 540 acgtatgctg gcatcgtcca agaccaactc taccactttt tccaccacta ggtacacaac 600 aaagctacaa atatacaact tcagttgacc ttggctgcgc tttctgacaa gataacagca 660 ctcactctgc agatgagaga gctttggaat ctttctttac tccgccaaaa aaaaatataa 720 taaaaaggtt tgagcgtcca cctctgaaag cctcaacatt tgtcaagaag aacaagatgg 780 gaactgatgg cagagaaatt cctttgtggg tctgggagac agaaaccaat gacactgaaa 840 aaagtattgc aaacaagctc tttgtccatc ccgcttccca accgttgact taagtaacca 900 ttctcccact gaatgagtat taatatttgt gtcatatctt taaataaaat atttatataa 960 aaaaaaaaaa aaaaaaaagg ccgcctcggc cactctgcgt tgataccact gctt 1014 <210> 176 <211> 961 <212> DNA <213> Oryzias javanicus <400> 176 aagcagtggt atcaacgcag agtggccatt acggccgggg agccagagag cgttcgtgtc 60 gatgcctcca cctctgtccc gtttctgcta aaccgtcggg accaacttta acgccgtaaa 120 atgttcttgt ctgcagctgc gcgctctgtt gtgtcacagg cggccaggca ggtcagaagt 180 ctgcatcggt ctgctgcacg cgctggagct ggtggcatct ttgtgcacag agatactcca 240 gacaacaatc ctgacactcc gtttgagttc actgaacaaa acaaaaagag gatagatgca 300 attctgtcaa tgtaccctga aggacacaaa caagcagcca cgatcccagt cttggatttg 360 gcccagaggc aacatggatg gcttcctatc tccgcaatga acaaggttgc tgaggttctg 420 ggtgttgcac caatgagagt gtatgaagta gcgacattct ataccatgtt cctgcgtcag 480 cctgtgggaa aatacttcat tcagatctgc acaacaacac catgcatgct ctgcaactcg 540 gacagcattc tggacgccat ccaaaacaaa ctgggtatca aggttggaga gacgactcca 600 gacaagatgt tcactctaat agaggtggaa tgcctgggtg cttgtgtaaa tgctccaatg 660 gtccagatca atgacaacta ttatgaggac cttacaccaa aggatattga gaatattatt 720 gatgaactta aagcagggag agtgccacca ccaggaccca ggaatggccg tttctcctgt 780 gagcctgcag gaggactaac ctccctgacg gcacctccga gtggaccagg gtttggtgtg 840 cgatctgacc tgtaaacgtc taagatggtt tttttttttg tcctgcttca tctggaagct 900 atctttaata tctgcagata ttaaaataaa aatgactgta aataaaatgt cctataacct 960 t 961 <210> 177 <211> 868 <212> DNA <213> Oryzias javanicus <400> 177 aagcagtggt atcaacgcag agtggccatt acggccgggg gagctacacc ctccaagctt 60 ttggagacat ggccgattcc ttcaagtctg attattttaa catgccagtt catatggttc 120 ctactgagct tgtagagaag gagttctggc gtctcgtcag caccatcgag gatgatgtca 180 ccgtggaata cggagcagac atcgcctcca aggagtttgg gagtggcttc cctgtgaaaa 240 acagccattt tgaagtgtct cctgatgatg agcattacct gagcagtggc tggaacctga 300 acaacatgcc ggtgctcgat gcctccgtgc tgacccatat tacagcagac atctgtggga 360 tgaaggttcc ctggctctat gtggggatgt gcttctcctc tttctgctgg cacattgagg 420 accactggag ctactccata aactatcttc actgggggga gccaaagaca tggtacggcg 480 ctcccggtta tgctgcagag cacctggaat cagtcatgaa gaaattggct cctgagctgt 540 ttgagtccca gccagatctc cttcaccagc tggtcaccat catgaatccc aacacgctga 600 tgaacaacgg catcccgatc tatcgcacca accagtgtgc tggtgagttc gtcatcacct 660 tccccagagc gtaccacagc ggattcaacc agggtttcaa ctttgctgag gctgtcaact 720 tctgcaccat ggactggatg cctattgggc gtagctgtgt ggatcactat cggcagctaa 780 gcagatactg tgtcttctct cacgatgaga tggtttgtaa catggccctc aaagcaaaca 840 ccatggatgt tgagctggca tcagccgt 868 <210> 178 <211> 2147 <212> DNA <213> Oryzias javanicus <400> 178 aagcagtggt atcaacgcag agtggccgag gcggcctttt tttttttntt tttttttgat 60 ttgtctgtca tttttaattc atattttgga agcaaacagc tattttttcc aactctactc 120 actttattct ttattaactg agttatgtct gcacagctca tgtctcacac acacagtttt 180 gtctgaacac gtcagaaata caaatccctc agtacaaagt tcaataaaaa aaaaatcaat 240 ttaagagtaa aatgaacacc tgtgttgtaa atctattctt tttattcaaa aaaatctttg 300 aagtaaaaat gtaaatcatc tttctatttt aaggcacatt gactaaaaaa gagcagcaaa 360 ttccctcttt ttttaagtgt tcaaacactt tatggaataa aagttttttg acgcaactcc 420 agcgatgtca cacaggtcaa aaagtacaaa ctatcaacca caagagggca tgagttcaga 480 ttaagttaaa ttggtgcaga acaaaagcct cattttaatt gtcagtgaca atcccctcct 540 attttaatcc acatctaaat agaataaata tgtatctgcc aacataccat gtttacggct 600 ggtttcagtg gagccgcctc ctcatttcct gctcaaactc atttaattcc caaagctctt 660 caacaaacaa aagctgcagc tccaggtgga gtaatgctgc tccagactca gagtccataa 720 ggttcataca gaaggagtaa atgtttcacc aggacggcgt tgtgcaatag aatcaacaag 780 attacatgac ttctgattgt gacaattggc ctttcaccac ggatcaaaat tcagagcttc 840 tctgacactc aaacactcgg ctaaaaatca ccaggaatag tcaactttaa tctgcggaat 900 ccaaaatttc cagaataaaa gcgtaaaagg ttcacagaac taacttttca aacaatcaaa 960 tgtgatgcat gttgtccact gatatcactt tgatgctgtt tttcctatta gtgcatgaaa 1020 aaatgaaaga gagagtggtc tttacactgt caacatggat gctgcaaata aaggttacag 1080 aacggattta atgggcttgg gggtgttgtt cagaaaaaat ttatctgtga tgaacgtcgg 1140 caggtacgac atgggtagcc agaagaactt ggcgtcccat cctggggaat agcggtagcg 1200 ggggtgaaca gcagcaacgg cgtgctccat acagccgacc accttcatca ggtcaccgtc 1260 cgtaagctga ccgaaccgtt ggtccacccc ttcaagagtt tgctctagga aaacctttcc 1320 ataatcctcc tgcacatcct gaggtagtct gtcccagagc ttcttcaaat tgctcttcac 1380 taaggaagtg tcggtcacgc tggtcttgaa gaagcccggc tcgatgcaca gaactttaac 1440 tccgaatgga gccatgttca aacgtagaca gtcattaaag gcttccactc cgtacttgga 1500 cacacaataa ggtccaccaa atggactgat gcgcccgaac acactggcca cattaaccac 1560 tcggcctcta gccttcttga tgaggggaag gacgctcagc gttacgtcga tgactccgtt 1620 cagattgacc gccagcatag acttgaaatc ctctatgttg agccagtcat tgggaccgga 1680 tggaacactg accccagcgt tatttacaac cgcccacagg cctttctccc caactagagt 1740 cttgatgaaa gctgctgcct tgctaacact ttccgatttg gtaacatcca gggacacggt 1800 gttgagtctt tccgaggaga gcttcttcag ctgagtttca cccatctcgg tgtagcaggc 1860 tgcgatcacc cggaatccca gctggtctag atgatgcgcc agtttgttac cgaagccgga 1920 gtcgcagcct gtgatgtaga cgtatttgtc ccccttgttg ggaactctct tgatttcttt 1980 cagccatcgg tagatgaacc aaacggccac cagtgcgagg atgtaaagaa acattttcgc 2040 gtcttttcgt cgtcagtcag tcagtgcata aatcgtctct gtgggtggac aggaatcaca 2100 cgagtgtccc cggccgtaat ggccactctg cgttgatacc actgctt 2147 <210> 179 <211> 829 <212> DNA <213> Oryzias javanicus <400> 179 aagcagtggt atcaacgcag agtgaccatt acggccggga gggatctgtc tgaacagatc 60 aagaaagtta caaaggagag tcatgtcaga gcagaaaaca ccgagctcat gctcagcttc 120 cagcggggac aagtcacact tccacagtat aagctcctcc tgtgttccct gtacgagatt 180 tacaaagctc tggaggaaga gctggacagg aactccaacc atgctggtgt tgcacccatt 240 tactttccat ctgaactggc cagactggag tccattgaga aagacctgga gtatttctac 300 agcaccaact ggagggagaa gatcgttgtt cctgctgcta cgaagagata ctgtcacagg 360 atcagacaga ttggcaaaga gaacccagag tttctggtgg cccacgctta cacccgttac 420 ctcggcgatc tgtccggagg ccaggttctt ggtcggatcg cccagaaatc catggggctg 480 aaaaccagcg agggtctgtc tttcttcgcc ttccctggag tctccagccc caacctgttc 540 aagcagctct accgcagccg aatgaacagc gtggagctga cggaggagca gaggaacggc 600 gtgctggagg aggcggtccg gtccttcgag ttcaacatcc aggtctttga tgacatccag 660 aagatgctgg acgtcacaga aaacaagctg cagaacagtt taacagacaa gtcaagagag 720 gctaaaacgc tccacgtccc gctcatcagg atggtgctgg gactttttgt ggctctggct 780 acagtcagca tgggattcta cgctctataa aattagactt ttttttttt 829 <210> 180 <211> 828 <212> DNA <213> Oryzias javanicus <400> 180 ggcaagaacg agctggccgc tgtcattccc ctagtggtca agagcgtgaa gtgcgccaca 60 gtgctctcgg acattttgcg gcggtgcact ctgaccacgc ccggcatggt gtcggctctg 120 cacagccgca ggaactctgg gaagttgatg tcactggaca aggcgccgct caggcagctg 180 ctggacgcca ccatcggggc ttacatcaac accacgcact cgcggcttac gcacatcagc 240 ccgcggcact acagcgagtt catagagttc ctggggaagg cccgggagac gtttatgatg 300 gctcacgacg gacacatcca gttcacccag ttcatagaca acctgaaaca gatctataag 360 ggcaaaaaga aactaatgat gctcgtgagg gagaggtttg gctgagagca aggctccact 420 ctcactttag gacttttcta tttacttgat tctgcctttt gaacttcctt tggactaaaa 480 gacgagtaaa aagagggatg tgacttgtag aatgaagcaa aaacagaaag gaagaaaaaa 540 atcaacagag ccacctgcgg tattattgtt cttgctgttg ttactgttat aaacagtatt 600 actattatta ttattaatat tattcctact ccgtgtacag acgtgttttt atttttcaga 660 agagaggaaa tttgtcacat tgtgaatgtt gtgtgtttct ctacatgtgt gcgagacgaa 720 aagtgaaaag gctttttttt tatttatttt ttagtcatct tttcctccct ttttttccgt 780 tgtccatttg agttacatgt tgtcgagcgg ctgaagccct tgtacaat 828 <210> 181 <211> 2119 <212> DNA <213> Oryzias javanicus <400> 181 aagcagtggt atcaacgcag agtggccatt acggccggga cccccgtcca cgccggggac 60 cgccggggac aaggggagtc agaattctgg acagagtcag cagcatattg aatgtgtgat 120 ttgcggagac aaatcgagcg gcaaacacta tggccagttc acctgcgagg gatgcaaaag 180 tttcttcaag aggagtgtac ggaggaactt aacctactcg tgtcgtgcca ataggaactg 240 tcccattgac cagcaccacc gaaatcagtg ccaatactgc cggctgaaga agtgtctaaa 300 agtggggatg cggcgggaag cggttcagcg aggacgaatg cctccaaccc aacccaaccc 360 aggccagtac gcgctgacaa atggagaccc tctgaatggc cactgctatc tgtccggata 420 catctcgtta ttgctgcggg ctgagcctta cccgacgtcc cggtacggga gccagtgcat 480 gcagcctaac aatatcatgg gcatcgagaa catctgcgag ctggcggctc gtttgctctt 540 cagcgccgtg gagtgggcga gaaacatccc tttctttccc gacctgcaga tcaccgacca 600 ggtgtccctt ctcaggctga catggagcga gttgtttgtg cttaacgcgg cccaatgttc 660 catgcctctg cacgtggccc ctctgcttgc tgcagcgggc ctccacgctt ccccgatgtc 720 cgcggaccgc gttgtggctt tcatggatca catccggatc ttccaggagc aagtggagaa 780 gcttaagact ctgcacgtgg actcggcaga gtacagctgc ctcaaggcga tcgtgctttt 840 cacatcagac gcctgcggcc tgtcggacgc tgctcacatc gagagtctac aggagaaatc 900 ccagtgcgcc ctggaggaat acgtcaggag ccaatacccg aaccaaccca gccgctttgg 960 caagctcctg ctgcggctgc cctctctgcg caccgtctcc tcctcggtaa tcgagcagct 1020 gttcttcgtc cgcttggtag gtaaaactcc tattgaaacc ctcatcaggg atatgctatt 1080 atccgggagc agcttcaact ggccttacat gtccatccaa tgatcctcat aagaaagagg 1140 gaaaaaagac aggaaaaagg accaaaatac agcacctccc cctccaccac caccacccac 1200 ccaatccttc ttcaagaaga ctatatgtag gacgttttct gacaaacttg gaagacatta 1260 ctttttttct gtcttctgga actgtgatgg aatacattat gtacagaaaa tatcggaact 1320 ggactttaca cctgtgtaaa tcctccctca tcttcaagaa caatactctt cattttgtaa 1380 aatactagtc tttattttcc tttttttttg ttaaaaaaaa taacaaataa aatgaaaaac 1440 atcatatgcg aagtaagaaa aaaaaagaat caagacttag cgggaaaata atgtttccaa 1500 gcaattataa gaattgtcct gtgtctatgt acctctctgt tttgtatttt tctggttcta 1560 aaccagggtt tctgtgattc tatactaata atttttgata taaccttttg cttcttataa 1620 tgagtgcgat atatgttgtc gaagctatgt tctccaagaa ttaaaattga agtgagaatc 1680 taaaaaacag aaaaataaag agatttagac aaataagaaa cagtctaatc gctgtgataa 1740 tatcaccact gatggctgaa cttttttttc tttttttttc aacaattgat aacgatggac 1800 ctgcatctgc agcaaactga cctccaggac atttttactg acatttttac tccaggatgt 1860 ctggggcgcc ttttccccgg gctgtgagcg cgcgtggagt cgtcaaagag gagagacctg 1920 aaaaatcaaa aagcactttt aatatatcat ttcaaataca ttttgtttgt ttcgtcttga 1980 aaaaaaaact ctcattgttt cttgaactta ttggttgttg ccttcaattt gcttactcca 2040 tgatgcagct tttttgcaga aaaggtcggt tgatcaagtt gtgtgatggt gactgtacta 2100 ttaaaaaaga aataggcaa 2119 <210> 182 <211> 794 <212> DNA <213> Oryzias javanicus <400> 182 tttttttttt ttcttttttt tctgttttta atactaactt ttatttgtca atctgtattg 60 tacattgaca ttagtgagaa cgaaagttaa ttttttataa accggttgag gacagagtac 120 aaaactcatt ggttttcatt aaaacagttc cagtatatgt aaatcagtac attaaaccag 180 ttaaaaaggg gtttagctct tgatactgaa atgcaaacca cgtcagtaaa ttacaaggca 240 aaaactttct gtattgcttg aactgaaatg tttttaagag aactagaaaa tgtaacaagc 300 gggaatgaag gtggatgaag tgaaaagtct ttacaagatt aggcaaaatg tgattgagga 360 gcagaggagg ggaaaaaagc ctcactaagg ccacaaaata tttatcaatg aatctaataa 420 atcactttat gctttgtaaa tgtagttttg ggtgtctggc ttttattttt caatttattg 480 acaacaatca gtcactcggt ttccatgcaa aaggctgctg cttggacagg atgttagagg 540 ctgcagggtc tgtgggatga gcattttcag tatctgtagt atggacttcg cgaccgagac 600 cgtgatctcc ttctgtgcga gctgtgttct cggccatatt tggtaggaga cggtgagctg 660 ctctgccgcc cgtactgtct ttcccattcg tccctttctt tctcacgccg ctcgcgttcc 720 ttcatgcgaa tcttgcgtgc catggctcgc agctctccct ctcgctcctg tcgtttgtgt 780 tcctgctgct ggat 794 <210> 183 <211> 2065 <212> DNA <213> Oryzias javanicus <400> 183 aagcagtggt atcaacgcag agtggccatt acggccgggg acacatcact tggttctttc 60 acaaagacaa cagaccagat gaggaaagga gggtaaaaac agagaaaaga ctgaaggaat 120 aaagaacagg agaagagaca aaccacagaa agatatctcc tgctgagcac acacttcagc 180 ttgtgtgcaa gtgagaggac aacccagcct gactgggact gcactgggag gacaggacaa 240 caccatggct gacagcgtga acgaggagtc cgattatgtc ccggggaaag atgagcttga 300 ctggggctat gaggaaggtg tagaatgggg actccatttc ccagcagcca atggtgaata 360 ccagtctccc attaatttga actccagaga ggcccaatat gacccctccc tgctggatat 420 cggtttatcc ccaaactatg tggtgtgtcg agactgcgaa gtcatcaacg atggacacac 480 tgtccgcatc ctcctcaagt ccaagtcagt ggttacaggg ggcccgttac caagtgacca 540 tgagtatgag cttcatgagg ttcggtttca ctggggcaag gaaaatcaga gggggtcgga 600 gcacactgtc aactttaagg ctttccccat ggagctccat ctgattcact ggaacagcac 660 tctgtttaac tcgttggagg acgctctggg gaggaagaac ggcatcctca tcatcgctct 720 gtttgtgcag gttggtaaag aacacttggg tctaaaggcc atcactgaag ttctacagga 780 cctgcagtac aaggggaaga gcaagatcat accatgtttc aaccccaaca ccctcctacc 840 tgatcctctg ctgagggact actgggtgta tgaagggtct ttgaccacgc ccccttgcag 900 tgaaagcgtc acctggatcc tctaccgtta ccccctcacc atctcacaga tgcagattga 960 ggagtttcgg aggttgcgtt ctcacgtcaa aggggcggag cttccagaag ggaatgacgg 1020 catgctggga gacaacttcc gtcctaccca acccctcagt gaccgtacgg ttcgcgctgc 1080 cttccagtga ctcctctgcc atctttaaac taactgtgac cccgcaggga aaacaaatca 1140 aaggggagag agaagcagaa gtgtgaggac gagaatggaa aaccaaggaa aggcaaagtt 1200 gatgggattg catattagct gcagactgaa ggtggacaaa gaagcttttg agctccaaac 1260 tttgctgcat gctttgtgtt gagtgtgtgc tggtaaaggt acagtgttcc tgttctgtag 1320 gtttgttttt cctttctttt ttatcactct cttgctctgt tttggtctga tgagctgccc 1380 gggagttgat gttctgtagt ttgagtcact ttttatgttt ctgtgtgtgt ggagagtaat 1440 ttatagaaaa aatataggaa gaactgagat ccaatccagc ataaaaatgt cttctttgaa 1500 taaaattcac ttaactttat aaagaaatat cagggctgta ctttgatgtg attctttaaa 1560 aactgctttg gcaacaaact catgataaga gaataaaata catcattttc tgactaaaga 1620 gttgtttcaa tgctataaag tcctcaagat agaccattaa atttgtgttt tattgcgaaa 1680 aaaatcatag agaaaaatta gtaaatgaaa catttactgt gtggcttttt taaataaaaa 1740 aatgttctaa ccacttccgt tacaatctat aaactatggt cactgagtaa gaacgtcact 1800 gtcatacatc ttctattgaa tcttcataac atcctacttt ttgtactagt tgttttgatt 1860 caatacaaga gagttcaaag cgatcctttt caccagtatg tctgtttgtt gtcttcaatg 1920 ggaccacgtg tgtcaaaatg aaaactgtga gaactgatga ctgttactgt aaagctacaa 1980 taaactacag cagtgactta actaagaaaa aaanaaaaaa aaaaaaaaag gccgcctcgg 2040 ccactctgcg ttgataccac tgctt 2065

Claims (13)

  1. 서열번호 1 내지 183으로 기재되는 모든 유전자 각각의 핵산 서열의 올리고뉴클레오티드 전부 또는 그의 상보가닥 분자가 집적된, 바다송사리의 트리클로산(triclonsan, TCS) 노출 여부 검출용 마이크로어래이 칩(microarray chip).
  2. 제 1항에 있어서, 상기 유전자는 바다송사리(Oryzias javanicus)로부터 유래된 것을 특징으로 하는 트리클로산 노출 여부 검출용 마이크로어래이 칩.
  3. 제 1항에 있어서, 서열번호 1 내지 125로 기재되는 유전자로 구성된 군으로부터 선택되는 유전자는 트리클로산 노출에 대응하여 발현이 감소하는 것을 특징으로 하는 트리클로산 노출 여부 검출용 마이크로어래이 칩.
  4. 제 1항에 있어서, 서열번호 126 내지 183으로 기재되는 유전자로 구성된 군으로부터 선택되는 유전자는 트리클로산 노출에 대응하여 발현이 증가하는 것을 특징으로 하는 트리클로산 노출 여부 검출용 마이크로어래이 칩.
  5. 1) 피검 시료에 노출된 실험군의 바다송사리와, 정상 대조군의 바다송사리에서 각각 RNA를 분리하는 단계;
    2) 단계 1)의 실험군 및 대조군의 RNA로부터 cDNA를 합성하면서 실험군과 대조군을 각기 다른 형광물질로 표지하는 단계;
    3) 단계 2)의 각기 다른 형광물질로 표지된 cDNA를 제 1항의 마이크로어래이 칩과 혼성화시키는 단계;
    4) 반응한 마이크로어래이 칩을 분석하는 단계; 및
    5) 분석한 데이터에서 제 1항의 마이크로어래이 칩에 집적된 유전자 발현 정도를 대조군과 비교하여 확인하는 단계를 포함하는, 시료내 트리클로산(triclonsan, TCS) 노출 여부 검출 방법.
  6. 제 5항에 있어서, 상기 시료는 생체시료, 식품시료, 화학시료, 공업시료, 임상시료 및 환경시료로 구성된 군으로부터 선택되는 어느 하나인 것을 특징으로 하는 트리클로산 노출 여부 검출 방법.
  7. 제 5항에 있어서, 상기 단계 2)의 형광물질은 Cy3, Cy5, FITC(poly L-lysine-fluorescein isothiocyanate), RITC(rhodamine-B-isothiocyanate) 및 로다민(rhodamine)으로 이루어진 군으로부터 선택되는 어느 하나인 것을 특징으로 하는 트리클로산 노출 여부 검출 방법.
  8. 1) 피검시료에 노출된 실험군의 바다송사리(Oryzias javanicus)와, 정상 대조군의 바다송사리에서 각각 RNA를 분리하는 단계;
    2) 단계 1)의 RNA를, 서열번호 1 내지 183으로 기재되는 각각의 유전자에 상보적이고 유전자를 증폭할 수 있는 프라이머 쌍을 모두 사용하여 정량 실시간 RT-PCR(Quantitative real-time reverse transcript polymerase chain reaction, qRT-PCR)을 수행하는 단계; 및
    3) 단계 2)의 유전자 산물을 대조군과 비교하여 발현 정도를 확인하는 단계를 포함하는, 시료내 트리클로산(triclonsan, TCS) 노출 여부 검출 방법.
  9. 제 8항에 있어서, 상기 시료는 생체시료, 식품시료, 화학시료, 공업시료, 임상시료 및 환경시료로 구성된 군으로부터 선택되는 어느 하나인 것을 특징으로 하는 트리클로산 노출 여부 검출 방법.
  10. 제 1항의 마이크로어래이 칩을 포함하는 바다송사리의 트리클로산(triclosan; TCS) 노출 여부 검출용 키트.
  11. 제 10항에 있어서, 스트렙타비딘-알칼리 탈인화효소 접합물질(strepavidin -like phosphatease conjugate), 화학형광물질(chemiflurorensce) 및 화학발광물질(chemiluminescent)로 이루어진 형광물질군으로부터 선택되는 어느 하나를 추가적으로 포함하는 것을 특징으로 하는 트리클로산 노출 여부 검출용 키트.
  12. 제 10항에 있어서, 혼성화에 사용되는 완충용액, RNA로부터 cDNA(complementary DNA)를 합성하기 위한 역전사효소, dNTPs(deoxynucleotide triphosphates) 및 rNTPs(ribonucleotide triPhosphates, 사전 혼합형 또는 분리 공급형), 표식시약, 및 세척 완충용액으로 이루어진 반응 시약군으로부터 선택되는 어느 하나를 추가적으로 포함하는 것을 특징으로 하는 트리클로산 노출 여부 검출용 키트.
  13. 서열번호 1 내지 183으로 기재되는 각각의 유전자에 상보적이고 유전자를 증폭할 수 있는 프라이머 쌍을 모두 포함하는 바다송사리의 트리클로산(triclosan; TCS) 노출 여부 검출용 키트.
KR1020160024104A 2016-02-29 2016-02-29 트리클로산 노출에 대응하는 바다송사리 유전자 및 이를 이용한 수생태계 환경오염 진단 방법 KR101656744B1 (ko)

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KR20140014642A (ko) * 2012-07-25 2014-02-06 한국해양과학기술원 노닐페놀 노출에 대응하는 바다송사리 유전자 및 이를 이용한 수생태계 환경오염 진단 방법

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