KR101563324B1 - manufacturing method of eye patch thereof - Google Patents

Abstract

The present invention relates to a method for manufacturing a patch for relieving eye fatigue wherein functional hydrogel is produced by mixing hydrogel, which responds to skin temperature when attached to an eye area, is slowly melted, is changed into a sol phase, and is absorbed into the skin of the eye area, with a functional material having effects of relieving eye fatigue and relaxing mind and a body, and then the patch for relieving eye fatigue is manufactured by using the produced functional hydrogel. The patch comprises a urethane film, nonwoven fabric, the functional hydrogel, and a release film. The hydrogel for producing the functional hydrogel comprises polyacrylic acid, glycerin, water, sodium hydroxide, agar, and polysorbate60. The functional material is obtained by mixing one or more from a jasmine extract, a rosemary leaf extract, and menthyl lactate. The functional hydrogel includes 99-99.99 wt% of the hydrogel and 1-0.01 wt% of the functional material.

Description

Technical Field [0001] The present invention relates to a patch for relieving eye fatigue using a skin temperature responsive functional hydrogel,

The present invention relates to a hydrogel which causes a change in state to a sol state while slowly melting in response to a skin temperature around the eye when attached to the periphery of the eye to thereby absorb it into the skin around the eyes, A functional hydrogel is prepared by mixing a functional material, and a method for producing a patch for relieving eye fatigue using the functional hydrogel.

Recently, as the computerization of business has rapidly expanded due to industrialization and division of labor, and the spread of VDT (Visual Display Terminal) has increased, VDT syndrome, a new occupational disease caused by office workers, has become a new social problem all over the world. (Lee, Seung-Deok, Kim, Bae-Seong, Korean Journal of Acupuncture and Moxibustion, 2001, 18, 70-83). Generally, VDT syndrome refers to a combination of health problems such as eye disorders, back pain, and mental stress that occur in occupants who handle VDT for a long period of time.

 The most common and often severe symptoms of VDT syndrome are eye fatigue (Dainoff MJ, et al., Human factors, 1981, 23, 421-437; Smith MJ, et al., Human factors, 1981 , 23, 387-400). More specifically, 395 VDTs and 141 non-VDTs in insurance companies, airline companies, post offices, and newspapers were compared with VDT groups. As a result, the VDT group was classified into 'eyes are sick', 'eyes are itchy' (Knave, BG, et al., J. Work Environ. Health, 1985, 11 (2)). , 457-466). In addition, symptoms of VDT syndrome include reduction in tear film break up time due to dry eye syndrome, and myopia due to the action of electromagnetic waves (Armaly MF, et al., Ophthal. , 1982, 1, 480-483; Tsubota K., Retina Eye Res., 1998, 4, 565-596)

Therefore, various medicines, natural foods, and the like are sought to improve the eye symptoms described above. As a dual medicinal product, a vision improving agent based on anthocyanoside extracted from wild blueberry is widely used in domestic and overseas. As a herbal medicine herbicide, Kjigae is widely used in Korea, China, Japan, etc. for maintenance of eyesight and improvement of eyesight To drink as tea.

[Prior Art Literature]

[Patent Literature]

Korean Patent Laid-Open No. 10-2003-0087451 (November 14, 2003)

Korean Patent Laid-Open No. 10-2005-0094079 (2015.09.27)

The present invention relates to a functional hydrogel containing at least one of jasmine extract, rosemary leaf extract and mentyllactate in a hydrogel which is slowly dissolved in the skin around the eyes while being adhered to the skin around the eyes when attached to the periphery of the eye, The present invention provides a patch for relieving eye fatigue using a skin temperature responsive functional hydrogel which is applied to a patch attached to the periphery of the eye to help relieve eye fatigue and mind and body stability.

According to an aspect of the present invention, there is provided a method of manufacturing a polyurethane foam, comprising the steps of: applying an adhesive (15) to one side of a urethane film (10) and bonding the nonwoven fabric (20) to the urethane film to which the adhesive is applied; Preparing a functional hydrogel (25) by mixing the hydrogel with a functional material that helps to relieve eye fatigue and mental and physical stability; Applying the functional hydrogel to the surface of the nonwoven fabric 20 or one side surface of the release film 30, and then bringing the functional hydrogel into close contact with the nonwoven fabric and the release film to form a patch sheet; Drying the patch sheet after heat treatment to form the functional hydrogel as a semi-solid functional hydrogel; Cutting the patch sheet having the semi-solid state of the functional hydrogel (25) into a shape corresponding to the application site of the neck; To prepare an eye patch,

Wherein the hydrogel for producing the functional hydrogel is composed of Polyacrylic acid, Glycerin, Water, Sodium hydroxide, Agar and Polysorbate 60, and the functional material is a mixture of at least one of jasmine extract, rosemary leaf extract and mentyllactate And the mixing ratio of the hydrogel and the functional material is 99 to 99.99% by weight of the hydrogel and 1 to 0.01% by weight of the functional material.

delete

delete

delete

The patch for relieving eye fatigue using the skin temperature responsive functional hydrogel according to the present invention prepared by the above method, when adhered to the periphery of the eye as described above, gradually melts in response to the skin temperature around the eyes, A functional hydrogel containing at least one of jasmine extract, rosemary leaf extract and mentyllactate is applied to a patch attaching to the eyes,

First, it contributes to the fatigue of the eyes and the mind and body stabilization, which not only relieves the eye fatigue caused by the computer, but also improves the concentration of the students'

Second, it prevents aging around the eye, suppresses and improves the formation of wrinkles around the eyes, maintains skin elasticity around the eyes,

Third, there is an effect that it can be used stably for a long period of time without side effects.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a process drawing showing a neck patch manufacturing method of the present invention,
FIG. 2 is a sectional view for explaining the neck patch construction of the present invention,

As shown in Fig. 1, the method for manufacturing a patch for relieving eye fatigue using the skin temperature responsive functional hydrogel of the present invention comprises the steps of:

Applying an adhesive (15) to one side of the urethane film (10) and bonding the nonwoven fabric (20) to the urethane film coated with the adhesive;

Preparing a functional hydrogel (25) by mixing the hydrogel with a functional material that helps to relieve eye fatigue and mental and physical stability;

Applying the functional hydrogel to the surface of the nonwoven fabric 20 or one side surface of the release film 30, and then bringing the functional hydrogel into close contact with the nonwoven fabric and the release film to form a patch sheet;

Drying the patch sheet after heat treatment to form the functional hydrogel as a semi-solid functional hydrogel;

Cutting the patch sheet having the semi-solid state of the functional hydrogel (25) into a shape corresponding to the application site of the neck; To prepare eye fatigue mitigation patches,

Wherein the hydrogel for producing the functional hydrogel is composed of Polyacrylic acid, Glycerin, Water, Sodium hydroxide, Agar and Polysorbate 60, and the functional material is a mixture of at least one of jasmine extract, rosemary leaf extract and mentyllactate And the mixing ratio of the hydrogel and the functional material is 99 to 99.99% by weight of the hydrogel and 1 to 0.01% by weight of the functional material.

In this case, dyeing or silk printing of a color selected from the urethane film or the nonwoven fabric before the urethane film 10 and the nonwoven fabric 20 are adhered is further added for coloring the eye patch, and the semi-solid state of the functional hydrogel Is formed by aging at 50 to 80 ° C for 2 to 4 days and then drying the aged functional hydrogel for 1 to 3 days.

Hereinafter, the efficacy of the functional substance exhibiting the eye fatigue reducing function of the present invention will be described.

- next -

1) Jasmine is used as raw material of fragrance of tea and tea in China and Taiwan, and India, China, Taiwan, Philippines and Indonesia are cold It is cultivated as an ornamental plant in the greenhouse in cool surroundings. Jasmine relaxes the nerves comfortably, cleanses the mind, fat splits, maintains skin elasticity (skin sensitive to dryness), improves concentration and restores fatigue .

2) The rosemary leaf is a compound word of Latin Ros (dew) and Marinus (sea). It means sterilization, disinfection and insecticidal action. It is said that the rosemary leaf is defeated in the old days without knowing the scientific basis of such efficacy.

Rosemary fragrance is used to stimulate the development of the brain by keeping the rosemary fragrance in the room of the examinee who has a lot of learning and growing children, and stimulates the development of the brain. When the human body is ingested, it stimulates the cerebral cortex and acts as an anticonvulsant. .

Rosemary also relieves symptoms such as nervousness and anxiety, stabilizes the mind, stress relieves headaches, and is also known to have a good condition recovery effect.

3) Mentyllactate is a cooling agent made of menthol as raw material. It has a long cooling effect and has a very soft inherent flavor. The raw material is mixed with glycol oil and perfume oil, and then shampoo, shower gel, form bach .

The active ingredient extraction method for extracting the eye fatigue relieving effect of the present invention from each of the raw materials is extracted by a hot water extraction method. As is well known, the obtained raw materials are washed and the washed raw materials are washed with water Refers to an extract obtained by supplying a mixture to a heating vessel together, heating the mixture to a strong fire, boiling the mixture, and boiling the mixture to a low temperature for several times.

An embodiment will be briefly described as follows.

Washing any one of the obtained raw materials;

Separating the washed raw material and mixing the pulverized raw material into a heating container at a weight percentage of 85 to 95% by weight of a raw material at a ratio of 5 to 15;

Heating the heating vessel to strong fire, boiling and boiling until the amount of water is less than 40 - 60%, and then removing the precipitate and suspension;

The precipitate and suspended matter are removed from the heated vessel to maintain 70 to 80% of water in the initial heating vessel, heated to a strong fire, boiled, and boiled until the amount of water is reduced by 10 to 20%.

Hereinafter, the eye fatigue mitigation patch using the skin temperature responsive functional hydrogel of the present invention and its manufacturing method will be described in detail as follows.

- next -

a) bonding the nonwoven fabric to one side of the urethane film

The step a) of the present invention is a step of applying the adhesive 15 to one surface of the urethane film 10 and then bonding the nonwoven fabric 20 as shown in Fig. 2, and the reason for using the urethane film 10 , It is safe to the skin, it can deform according to the shape of the bending of the skin, and it suppresses the evaporation of water.

The reason why the nonwoven fabric 20 is used is that it maintains a close contact force with the skin and is safe to the skin and does not sufficiently deform the skin temperature responsive hydrogel of the present invention even when stored for a long period of time .

In order to colorize the neck patch of the present invention, the urethane film 10 and the nonwoven fabric 20 before dyeing or silk printing may be used in the color of the urethane film or the nonwoven fabric.

b) preparing a skin temperature responsive hydrogel

The step (b) of the present invention is a step of producing a functional hydrogel having an effect of helping the fatigue and mental and physical stability of the eye of the present invention. This is a main feature of the present invention and will be described separately below.

c) preparing a skin temperature responsive functional hydrogel

In the step c) of the present invention, after the functional hydrogel prepared in the step b) is applied to the surface of the nonwoven fabric 20 or the one surface of the release film 30, the functional hydrogel is immersed in the non- And the non-woven fabric coated with the functional hydrogel on one side is adhered to the release film by a rolling machine in such a manner that the release film 30 and the nonwoven fabric 20 are adhered to each other It is assembled.

d) Formation of Functional Hydrogel Semi-Solid State of Patch Sheet

In step d) of the present invention, the patch sheet is dried after heat treatment to form the functional hydrogel 25 as a semi-solid functional hydrogel. In one embodiment, the semi-solid state of the functional hydrogel is formed by 50 To 80 ° C for 2 to 4 days, and then the aged functional hydrogel is dried for 1 to 3 days.

The functional hydrogels existing between the nonwoven fabric 20 and the release film 30 are aged at 50 to 80 ° C. for 2 to 4 days and then dried for 1 to 3 days to form a semi-solid functional hydrogel So that it does not flow out of the functional hydrogel during distribution or storage.

The reason for aging at 50 to 80 ° C. for 2 to 4 days is that at least one of hydrogel composed of polyacrylic acid, glycerin, water, sodium hydroxide, agar and polysorbate 60 and jasmine extract, rosemary leaf extract and mentyllactate To be stabilized by the action of an enzyme or a microorganism of the functional substance containing the enzyme.

e) Patch sheet cutting step

The step e) of the present invention is a step of cutting the patch sheet in which the functional hydrogel 25 is in a semi-solid state to a shape similar to the application site of the human body, .

The method of manufacturing the skin temperature responsive hydrogel according to the above-described step b) of the method for manufacturing a patch for alleviating eye fatigue using the skin temperature responsive functional hydrogel of the present invention will be described as follows .

- next -

The functional hydrogel preparation method of the present invention is a functional hydrogel preparation comprising a hydrogel formed of polyacrylic acid, glycerin, water, sodium hydroxide, agar, polysorbate 60 and a functional material containing at least one of jasmine extract, rosemary leaf extract and mentyllactate As shown in FIG.

The mixing ratio of the hydrogel and the functional material is preferably 99 to 99.99% by weight of the hydrogel and 1 to 0.01% by weight of the functional material.

The reason why the mixing ratio of the hydrogel and the functional material is 99 to 99.99% by weight of the hydrogel and 1 to 0.01% by weight of the functional material is that the eye patch of the present invention has a good adhesion to the eyes, It helps not only to relieve eye fatigue by computer by giving help, but also to improve the concentration of classes by the examinees, to prevent aging around the eyes, to suppress and improve wrinkles around the eyes, to maintain skin elasticity around the eyes , And to demonstrate efficacy for long-term stable use without adverse effects around the eyes,

If more than 1 wt% of the functional material is used, it is more than necessary. If less than 0.01 wt% of the functional material is used, it helps the eye fatigue and mental and physical stability, thereby relieving the eye fatigue caused by the computer, , There is a problem that the effect of preventing the aging of the eyes around the eyes, suppressing the wrinkle formation around the eyes, and maintaining the elasticity of the skin around the eyes becomes insignificant,

The mixing ratio of the hydrogel and the functional material forming the functional hydrogel is preferably 99 to 99.99% by weight of the hydrogel and 1 to 0.01% by weight of the functional material.

On the other hand, the hydrogel is composed of 5-15 wt% of polyacrylic acid, 10-40 wt% of glycerin, 1-10 wt% of sodium hydroxide, 0.1-3 wt% of Agar, 0.1-3 wt% of Polysorbate 60, If the composition ratio of each component forming the hydrogel is more than or less than the above-mentioned preferable range, the hydrolysis power is lowered due to the lowering of the water absorption power to the skin, and the hydrogel is less viscous, There is a problem that the dissolution of the hydrogel due to the temperature response is not smoothly performed.

The polyacrylic acid, glycerin, sodium hydroxide, agar (culture solution), Polysorbate 60 (polysorbate 60), and the remaining water, which form the hydrogel, Since these components are widely used, a detailed description thereof will be omitted.

Examples of the functional hydrogel composition of the present invention are shown in Table 1 below.

Raw material name Experimental Example  One
(weight%) Experimental Example  2
(weight%) Experimental Example  3
(weight%) Experimental Example  4
(weight%) Experimental Example  5
(weight%) Jasmine extract 0.1 0.1 Rosemary extract - 0.1 0.1 - Menthilactate - - 0.01 0.01 - D.W 99.9 99.9 99.99 99.79 100 Sum 100 100 100 100 100

The eye fatigue measurement example according to the present invention was as follows.

* Experimental Example *

We used a method to measure the temperature around the eyes using the infrared heat sensor used in ophthalmology.

The temperature was measured before and after attaching the goggle-like patch to which the composition was added. A total of 10 subjects selected for the experiment were allowed to watch TV without sleeping from 10 o'clock in the night to 10 o'clock in the next morning. The results of the experiment are the same as those in Tables 2 to 5 below.

*Experiment result*

Example 1 subject A B C D E Before attachment 37.4 37.9 37.5 37.1 37.8 After attachment 37.2 37.8 37.2 36.8 37.4 subject F G H I J Before attachment 36.9 38 37.6 37.2 37.1 After attachment 36.8 37.7 37.2 37.1 36.8

Example 2. subject A B C D E Before attachment 37.2 37.8 37.6 37.2 37.7 After attachment 37.0 37.7 37.4 36.9 37.4 subject F G H I J Before attachment 36.8 37.9 37.7 37.2 37.3 After attachment 36.4 37.6 37.4 37.0 36.8

Example 3. subject A B C D E Before attachment 37.6 37.7 37.4 37.3 37.8 After attachment 37.4 37.2 37.1 37.1 37.2 subject F G H I J Before attachment 36.9 38 37.6 37.5 37.4 After attachment 36.7 37.6 37.1 37.2 37.1

Example 4. subject A B C D E Before attachment 37.4 37.8 37.5 37.6 37.9 After attachment 36.7 37.0 36.4 36.6 36.7 subject F G H I J Before attachment 37.2 37.9 37.8 37.7 37.8 After attachment 36.2 36.4 36.7 36.2 36.2

The temperature around the eye after patch attachment of Example 4 according to the present invention was lowered from 0.7 to 1.6 at least compared to before the attachment. From the above, it can be seen that the composition of Example 4 is effective for improving eye fatigue.

As described above, the eye patch manufactured by the method of the present invention helps the eye fatigue and mental and physical stability without adverse effects on the skin, thereby relieving the eye fatigue caused by the computer, It is possible to prevent aging around the eyes, to suppress and improve the generation of wrinkles around the eyes, to maintain the skin elasticity around the eyes, and to use the composition stably for a long period of time without adverse effects around the eyes.

10: urethane film 15: Adhesive
20: Nonwoven fabric 25: Hydrogel
30: release film

Claims (9)

Applying an adhesive (15) to one side of the urethane film (10) and bonding the nonwoven fabric (20) to the urethane film coated with the adhesive;
Preparing a functional hydrogel (25) by mixing the hydrogel with a functional material that helps to relieve eye fatigue and mental and physical stability;
Applying the functional hydrogel to the surface of the nonwoven fabric 20 or one side surface of the release film 30, and then bringing the functional hydrogel into close contact with the nonwoven fabric and the release film to form a patch sheet;
Drying the patch sheet after heat treatment to form the functional hydrogel as a semi-solid functional hydrogel;
Cutting the patch sheet having the semi-solid state of the functional hydrogel (25) into a shape corresponding to the application site of the neck; To prepare an eye patch,
Wherein the hydrogel for producing the functional hydrogel is composed of Polyacrylic acid, Glycerin, Water, Sodium hydroxide, Agar, Polysorbate 60, and the functional material is a mixture of at least one of jasmine extract, rosemary leaf extract and mentyllactate Wherein the mixing ratio of the hydrogel to the functional material is from 99 to 99.99% by weight of the hydrogel and from 1 to 0.01% by weight of the functional material, and a method for manufacturing a patch for alleviating eye fatigue using the skin temperature responsive functional hydrogel .
The method according to claim 1,
A step of dyeing or silk printing the selected color on the urethane film or the nonwoven fabric before the urethane film 10 and the nonwoven fabric 20 are adhered is further added to colorize the eye patch. The skin temperature responsive functional hydrogel A method for manufacturing a patch for use in relieving eye fatigue. The method according to claim 1,
Wherein the hydrogel comprises 5 to 15 wt% of polyacrylic acid, 10 to 40 wt% of glycerin, 1 to 10 wt% of sodium hydroxide, 0.1 to 3 wt% of Agar, 0.1 to 3 wt% of Polysorbate 60, A method for manufacturing a patch for relieving eye fatigue using a temperature responsive functional hydrogel. The method according to claim 1,
Wherein the functional hydrogel comprises 99.8 to 99.9% by weight of a hydrogel and 0.1 to 0.2% by weight of a jasmine extract. The method according to claim 1,
Wherein the functional hydrogel comprises 99.8 to 99.9% by weight of a hydrogel and 0.1 to 0.2% by weight of a rosemary extract. The method according to claim 1,
Wherein the functional hydrogel comprises 99.98 - 99.99% by weight of hydrogel and 0.01 - 0.02% by weight of mentyllactate. The method according to claim 1,
Wherein the functional hydrogel comprises 99.75 to 99.79% by weight of hydrogel, 0.1 to 0.12% by weight of jasmine extract, 0.1 to 0.11% by weight of rosemary extract and 0.01 to 0.02% by weight of mentyllactate. (Method for manufacturing eye fatigue mitigation patch using gel). The method according to claim 1,
The semi-solid state of the functional hydrogel is aged at 50 to 80 ° C for 2 to 4 days, and then the aged functional hydrogel is dried for 1 to 3 days. The skin hydrothermal gel Method of manufacturing a patch. A patch for relieving eye fatigue using a skin temperature responsive functional hydrogel produced by the method of any one of claims 1 to 8.

Images