KR101547361B1 - 엔도셀린 효능제 투여를 통한 방사선 요법에 대한 종양 세포의 감작 - Google Patents

엔도셀린 효능제 투여를 통한 방사선 요법에 대한 종양 세포의 감작 Download PDF

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KR101547361B1
KR101547361B1 KR1020097006395A KR20097006395A KR101547361B1 KR 101547361 B1 KR101547361 B1 KR 101547361B1 KR 1020097006395 A KR1020097006395 A KR 1020097006395A KR 20097006395 A KR20097006395 A KR 20097006395A KR 101547361 B1 KR101547361 B1 KR 101547361B1
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radiation therapy
composition
tumor
endocellin
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KR20090069279A (ko
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아닐 구라티
구루 레디
루이지 레나즈
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스펙트럼 파마슈티컬즈 인크
더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
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    • A61K38/22—Hormones
    • A61K38/2285—Endothelin, vasoactive intestinal contractor [VIC]
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device

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  • General Chemical & Material Sciences (AREA)
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  • Radiology & Medical Imaging (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020097006395A 2006-08-31 2007-08-27 엔도셀린 효능제 투여를 통한 방사선 요법에 대한 종양 세포의 감작 Expired - Fee Related KR101547361B1 (ko)

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US82419706P 2006-08-31 2006-08-31
US60/824,197 2006-08-31

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KR20090069279A KR20090069279A (ko) 2009-06-30
KR101547361B1 true KR101547361B1 (ko) 2015-08-25

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US (2) US8394757B2 (enExample)
EP (1) EP2059254B1 (enExample)
JP (1) JP5306208B2 (enExample)
KR (1) KR101547361B1 (enExample)
CN (1) CN101534852B (enExample)
BR (1) BRPI0722292A2 (enExample)
CA (1) CA2661833C (enExample)
DK (1) DK2059254T3 (enExample)
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IL (1) IL197335A (enExample)
MX (1) MX2009002308A (enExample)
NO (1) NO20091203L (enExample)
RU (1) RU2009111605A (enExample)
WO (1) WO2008027839A1 (enExample)
ZA (1) ZA200901425B (enExample)

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US8026216B2 (en) 2002-10-24 2011-09-27 Spectrum Pharmaceuticals, Inc. Methods and compositions for contributing to the treatment of cancers
US20070032422A1 (en) 2002-10-24 2007-02-08 Spectrum Pharmaceuticals, Inc. Methods, compositions and articles of manufacture for contributing to the treatment of cancers
ES2541657T3 (es) 2006-08-31 2015-07-23 Spectrum Pharmaceuticals, Inc. Sensibilización de células tumorales a terapia de radiación a través de la administración de agonistas de endotelina
JP2010539007A (ja) * 2007-09-11 2010-12-16 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト 治療剤としてのペプチドの使用
EP2340034B2 (en) * 2008-08-07 2019-02-13 The United States Of America, As Represented By The Secretary, Department of Health and Human Services Radioprotectants targeting thrombospondin-1 and cd47
US9308235B2 (en) 2012-05-09 2016-04-12 Spectrum Pharmaceuticals, Inc. Treatment of primary and metastatic carcinoma
TWI699403B (zh) 2015-09-25 2020-07-21 日商日本化藥股份有限公司 偶氮化合物、印墨組成物、記錄方法及著色體

Citations (1)

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WO2004037235A2 (en) 2002-10-24 2004-05-06 The Board Of Trustees Of The University Of Illinois Method and composition for preventing and treating solid tumors

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Publication number Publication date
MX2009002308A (es) 2009-09-07
ES2541657T3 (es) 2015-07-23
IL197335A0 (en) 2011-08-01
KR20090069279A (ko) 2009-06-30
RU2009111605A (ru) 2010-10-10
US20130150649A1 (en) 2013-06-13
BRPI0722292A2 (pt) 2014-04-15
CN101534852A (zh) 2009-09-16
WO2008027839A1 (en) 2008-03-06
EP2059254A1 (en) 2009-05-20
EP2059254B1 (en) 2015-04-08
JP5306208B2 (ja) 2013-10-02
IL197335A (en) 2013-07-31
US8957014B2 (en) 2015-02-17
DK2059254T3 (en) 2015-07-13
CA2661833C (en) 2016-01-26
JP2010502638A (ja) 2010-01-28
NO20091203L (no) 2009-03-23
CN101534852B (zh) 2013-02-13
US20080318846A1 (en) 2008-12-25
US8394757B2 (en) 2013-03-12
ZA200901425B (en) 2010-04-28
CA2661833A1 (en) 2008-03-06

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