KR101488921B1 - Mint liquid for improving digestive functions and manufacturing method thereof - Google Patents

Abstract

The present invention relates to a hot-water extract of a herbal medicine including dermis, health and broiler chick; And menthol dissolving solution prepared by dissolving L-menthol in ethanol; and a process for producing the same.
According to the present invention, gentle stimulation is given to the mucous membrane of the digestive tract and gastrointestinal tract by the efficacy and pharmacological action of the herbal medicine contained in the mint name sap solution to promote digestion by promoting secretion of digestive juice, , It is possible to suppress gastrointestinal pain in the stomach, to prevent gastro-intestinal ulceration, to add menthol solution, to eliminate nausea during digestion failure, to remove the fragrance peculiar to medicine, and to obtain a refreshing drinking feeling .

Description

TECHNICAL FIELD The present invention relates to a mint liquid for improving the digestive function and a method for producing the same,

More particularly, the present invention relates to a mint liquid for improving the digestive function and a method for producing the mint liquid for improving the digestive function, ≪ / RTI >

As the industry has developed and rapidly modernized, modern people's diet has become westernized. Such changes in eating patterns have caused incompatibility with the metabolism of the human body, and increased intake of high-calorie foods, instant foods and high-fat foods The consumption of fiber and the like is reduced, and the lack of exercise is caused by lifestyle pursuing comfortable life, and functional digestive disorder becomes a big problem to modern people.

Functional digestive disorder refers to a clinical syndrome in which the patient has symptoms of digestive system even though no gastric lesion is found in the stomach, and there are types of upper gastrointestinal type and lower gastrointestinal type.

Especially, the upper gastrointestinal type, which occurs most commonly in Korea, can be expressed as heartburn, trimming, nausea, vomiting, dyspepsia, postprandial discomfort, and abdominal pain in the fasting state, and can be expressed as neurogenic gastroenteritis and neurogenic gastritis.

Lower gastrointestinal tract diseases include postoperative bowel obstruction, post-gastrectomy dumping syndrome, irritable bowel syndrome in the lower gastrointestinal tract, constipation diarrhea, and the like.

In order to prevent and treat these functional digestive disorders, Antacid, Histamine Antagonist and Proton Pump Inhibitor, which are currently most commonly used for the prevention and treatment of functional digestive disorders, ), Cholinergic inhibitors, gastric mucosal protective agents to increase the resistance of the gastric lining to gastrointestinal tract and to help recovery. Recently, Helicobacter pylori, a type of germs living in the stomach, However, none of them has provided clinically satisfactory effects, and some of them have suffered from constipation, diarrhea, allergic rejection, fever, It is known to cause side effects such as headache or tiredness .

In addition, the existing preventive and therapeutic agents for functional digestive disorders often fail to properly take medication due to the psychological rejection of the medicines and the peculiar flavor and taste of the medicines.

Disclosure of Invention Technical Problem [8] Accordingly, the present invention has been made to solve the above-mentioned problems, and it is an object of the present invention to provide a gentle stimulation to the mucous membrane of the digestive tract and gastrointestinal tract by promoting secretion of digestive juices, It stimulates digestion by activating interlocking action, suppresses gastrointestinal spastic pain, anti-gastric ulcer action is possible, and also menthol dissolving liquid is added to eliminate nasty digestion, And to provide a method for producing a mint extract having improved digestive function and a method for producing the same.

In order to solve the above-described problems, the present invention provides a hot-water extract of a herbal medicine including dermis, health and broiler chickens; And menthol dissolving solution obtained by dissolving L-menthol in ethanol; and a mint stable liquid for improving digestion function.

At this time, the hot-water extract liquid is characterized by adding 0.5 to 10 parts by weight of dermis, 0.1 to 5 parts by weight of health, and 0.1 to 5 parts by weight of broiler to an extractor per 100 parts by weight of purified water.

In addition, the hot-water extract solution is also characterized in that the herbal medicine including dermis, health, and broiler is put into an extractor, heated with purified water, and filtered.

Here, the menthol solution is also characterized in that 0.05 to 1 part by weight of the menthol solution is mixed per 100 parts by weight of the filtered hot water extract.

The present invention is also characterized in that 0.1 to 1 part by weight of a mating agent, 5 to 15 parts by weight of a sweetener and 0.01 to 0.15 part by weight of a preservative are further mixed per 100 parts by weight of the filtered hot water extract.

At this time, the mating agent includes citric acid hydrate, sodium citrate hydrate and sodium chloride, the sweetener includes stevioside and high fructose, and the preservative is sodium benzoate.

Furthermore, the menthol solution is also characterized by dissolving 5 to 20 parts by weight of L-menthol per 100 parts by weight of ethanol.

Herein, the menthol solution may be prepared by adding 200 to 250 parts by weight of peppermint oil, 150 to 200 parts by weight of peppermint essence, 50 to 100 parts by weight of natural lime oil and 10 to 50 parts by weight of eucalyptus oil per 100 parts by weight of ethanol. Feature.

The present invention also relates to a process for weighing materials; An extracting step of adding a herbal medicine including dermis, health and broiler to an extractor, adding purified water, and then heating to extract the hot water extract; A filtration step of filtering the extracted hot water extraction liquid; A first dissolving step of further mixing and dissolving a mating agent, a sweetener and a preservative in the filtered hot water extract solution; A second dissolving step of dissolving L-menthol in ethanol to prepare a menthol dissolving solution; And a mixing step of mixing the respective dissolving solutions dissolved from the first dissolving step and the second dissolving step.

At this time, the extraction step is characterized by adding 0.5 to 10 parts by weight of dermis, 0.1 to 5 parts by weight of health, and 0.1 to 5 parts by weight of broiler to an extractor per 100 parts by weight of purified water.

In addition, the extraction process is performed at 90 to 100 ° C for 1.5 to 2.5 hours or at 120 to 130 ° C for 0.5 to 1.5 hours.

In addition, the first dissolving step is characterized in that 0.1 to 1 part by weight of a mating agent, 5 to 15 parts by weight of a sweetener and 0.01 to 0.15 part by weight of a preservative are further mixed and dissolved per 100 parts by weight of the filtered hot water extract .

Here, the mating agent includes citric acid hydrate, sodium citrate hydrate, and sodium chloride, and the sweetener includes stevioside and high fructose, and the preservative is sodium benzoate.

In addition, the second dissolving step is also characterized in that 5 to 20 parts by weight of L-menthol is dissolved per 100 parts by weight of ethanol to prepare a menthol solution.

In the second dissolving step, 200 to 250 parts by weight of peppermint oil, 150 to 200 parts by weight of peppermint essence, 50 to 100 parts by weight of natural lime oil and 10 to 50 parts by weight of eucalyptus oil are dissolved and dissolved per 100 parts by weight of ethanol There are also features that.

In addition, the mixing process is also characterized in that 0.05 to 1 part by weight of the dissolving menthol is mixed per 100 parts by weight of the filtered hot water extract.

In addition, the method further includes a filling step of filling the container with the carbonic acid gas after the mixing step.

According to the present invention, gentle stimulation is given to the mucous membrane of the digestive tract and gastrointestinal tract by the efficacy and pharmacological action of the herbal medicine contained in the mint name sap solution to promote digestion by promoting secretion of digestive juice, , It is possible to suppress gastrointestinal pain in the stomach, to prevent gastro-intestinal ulceration, to add menthol solution, to eliminate nausea during digestion failure, to remove the fragrance peculiar to medicine, and to obtain a refreshing drinking feeling .

BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is a flowchart showing a method for producing a mint serum solution for improving digestion function according to the present invention. Fig.

The present inventors have failed to provide a clinically satisfactory effect of a preventive and therapeutic agent for functional digestive disorders for the prevention and treatment of functional digestive disorders due to the improvement of the digestive function, and some of them have suffered from constipation, diarrhea, allergic rejection, fever , Headache or tiredness, etc. Also, it is recognized that there are problems that the user may not be able to take the medicine properly due to the psychological rejection of the drug and the unique and bitter flavor and taste of the drug. As a result of repeated researches and efforts, it has gently stimulated the mucous membrane of the digestive tract and gastrointestinal tract by the efficacy and pharmacological action of the herbal medicine contained in the mint name sap to promote digestion by promoting secretion of digestive juice, Thereby promoting digestion, suppressing gastrointestinal spastic pain, capable of gastric ulcerative action, The present invention has been accomplished on the basis of the present invention, which relates to a mint liquid solution for improving the digestive function and a method for producing the mint liquid, which is capable of eliminating the incomprehensibility upon digestion failure by adding a dissolving liquid,

Hereinafter, the configuration of the present invention will be described in detail with reference to the drawings with reference to the drawings.

As shown in FIG. 1, the method for producing a mint flavor solution for improving digestion function according to the present invention includes a weighing step (S10), an extraction step (S20), a filtration step (S30), a first dissolution step (S40) The second dissolving step (S50), the mixing step (S60), and the filling step (S70) are performed. Hereinafter, the detailed process will be described in detail.

[ Weighing  fair( S10 )]

First, the weighing step (S10) is a step of weighing the materials serving as the raw materials of the mint serum solution for improving the digestion function. The weighing step (S10) is a step of weighing 0.5 to 10 parts by weight of dermis per 100 parts by weight of purified water, 0.1 to 5 parts by weight of health, 0.1 to 1 part by weight of a mating agent, 5 to 15 parts by weight of a sweetener and 0.01 to 0.15 part by weight of a preservative are contained per 100 parts by weight of the hot water extract solution.

In order to prepare the menthol solution, 5 to 20 parts by weight of L-menthol, 200 to 250 parts by weight of peppermint oil, 150 to 200 parts by weight of peppermint essence, 50 to 100 parts by weight of natural lime oil and 100 parts by weight of eucalyptus oil 10 to 50 parts by weight.

[Extraction process ( S20 )]

The extraction step (S20) is a step of adding 0.5 to 10 parts by weight of dermis, 0.1 to 5 parts by weight of health, and 0.1 to 5 parts by weight of broiler to 100 parts by weight of purified water, followed by heating to extract the hot water extract solution.

That is, a herbal medicine containing dermis, health and broiler is put into an extractor, purified water is added, and then heated and extracted to obtain a hot-water extract.

Dandruff is a medicinal product of the citrus fruit of the Citrus Unshiu Markovich tree. It helps to strengthen the function of the spleen. It helps to strengthen the function of the spleen, so that only the abdominal cavity, trimming, vomiting, nausea, indigestion, It is a medication that is used to relieve symptoms, dilute symptoms and feces.

The pharmacological actions of the dermis include digestive stimulation, digestive stimulation, germane, anti-ulcer, antidiarrheal secretion, antiallergic action, promotion of bile secretion, inhibition of uterine smooth muscle and antibacterial action.

The dermis is preferably heated in an extractor in an amount of 0.5 to 10 parts by weight per 100 parts by weight of purified water. When the dermis is added to the extractor in an amount of less than 0.5 part by weight, the dermis may be insufficient in the above- If it is put in an extractor and it is heated more than 10 parts by weight, it will exceed the recommended intake amount, and side effects such as headache and diarrhea may occur.

The above-mentioned health (dry zingiber) is a dried root of ginger (Zingiber Officinale Roscoe), which acts on the digestive system by warming the body's midgut and is effective in the symptom of vomiting or frequent vomiting It is also used to treat pain in the lower abdomen or scrotum.

Pharmacological actions of the above health include gastric secretion promotion, activation of intestinal peristalsis, promotion of digestion, vomiting relaxation, promotion of blood circulation, anti-inflammation and analgesic action.

When the health is less than 0.1 part by weight and heated in an extractor, the health and pharmacological actions described above may be insufficient. When the health is excessive, If it is heated in excess of 5 parts by weight in the extractor, it will exceed the recommended amount.

The broth is a shell of Cinnamomum Cassia Blume. It promotes blood circulation, warms the body, stops the pain caused by cold of the stomach, stimulates the mucous membrane of the stomach, It is an efficacious drug that stimulates the secretion, suppresses the gastrointestinal pain of the stomach, accelerates the movement of the gastrointestinal tract and releases the gas.

The broiler is preferably heated in an extractor in an amount of 0.1 to 5 parts by weight per 100 parts by weight of purified water. When the broiler is added to an extractor in an amount of less than 0.1 part by weight, it may be insufficient in the efficacy and pharmacological effects described above. If it is heated in excess of 5 parts by weight in the extractor, it will exceed the recommended amount.

In the extracting step (S20), the herbal medicine containing the dermis, health and broiler is added to an extractor, purified water is added, and the extract is heated at 90 to 100 DEG C for 1.5 to 2.5 hours, It is preferable that the extraction is carried out by heating for 0.5 to 1.5 hours. If the extraction is performed in excess of or above the range of the temperature and the execution time, the hydrothermal extract may be in an optimal state capable of exhibiting the above- This is because the yield can be lowered.

[Filtration process S30 )]

The filtration step (S30) is a step of performing the extraction step (S20) and filtering the extracted hot water extraction liquid.

That is, in the extraction step (S20), the extracted hot water extract is passed through a filter provided with a porous filter medium to remove dermis, health and broiler residuals which may remain in the extracted hot water extract, To obtain a hot water extract solution.

[First dissolution step (S40)]

The first dissolving step (S40) is a step of performing the filtration step (S30), further mixing and dissolving a mating agent, a sweetener and a preservative in the filtered hot water extract solution.

That is, 0.1 to 1 part by weight of a mating agent, 5 to 15 parts by weight of a sweetener and 0.01 to 0.15 part by weight of a preservative are further mixed and dissolved per 100 parts by weight of the filtered hot water extract.

The mating agent is added for the purpose of concealing bitter taste peculiar to the herbal medicine, and it mainly includes citric acid hydrate, sodium citrate hydrate and sodium chloride.

When the mating agent is added in an amount of less than 0.1 part by weight, the bitterness unique to the desired herbal medicine may not be concealed, and 1 part by weight of the mating agent may be added. And the content of the sweetener and the preservative to be mixed relatively decreases if added in excess.

The sweetener is added together with the mating agent for the purpose of concealing the bitter taste peculiar to the herb medicine, and it mainly includes stevioside (purity of 50%) and high fructose.

When the sweetener is added in an amount of less than 5 parts by weight, it may not be possible to conceal the bitter taste peculiar to the desired herbal medicine, and when the sweetener is added in an amount of more than 15 parts by weight This is because the content of the mating agent and the preservative which are relatively mixed is decreased.

The preservative is added for the purpose of inhibiting and preventing the propagation of bacteria and microorganisms in the hot-water extract solution. In the present invention, sodium benzoate is used.

The sodium benzoate is a white crystalline powder having the formula C ₇ H ₅ NaO ₂ , which inhibits the growth of bacteria and fungi. The sodium benzoate has a broad antimicrobial range, and its effect is enhanced in a low pH range.

When the preservative is added in an amount of less than 0.01 part by weight, the desired preservation role may be insufficient. When the preservative is added in an amount exceeding 0.15 part by weight, .

[Second dissolution step (S50)]

The second dissolving step (S50) comprises: 5 to 20 parts by weight of L-menthol, 200 to 250 parts by weight of peppermint oil, 150 to 200 parts by weight of peppermint essence, 50 to 100 parts by weight of natural lime oil and 10 to 100 parts by weight of eucalyptus oil, To dissolve 50 parts by weight of the menthol solution.

The L- menthol (L-menthol) of the formula is C ₁₀ H ₂₀ O as the alcohol, and the crystal that can be produced by the leaves or stems of peppermint steam distillation or powder, and a refreshing flavor and refreshing taste, is dissolved hangover effects and , Preservation, sterilization, dryness and dressing.

The L-menthol preferably contains 5 to 20 parts by weight, and if the amount of the L-menthol is less than 5 parts by weight, the effect described above may be deteriorated. If the amount of the L-menthol is more than 20 parts by weight, irritation or itching may be caused to be.

The above-mentioned peppermint oil is extracted from peppermint leaves. It causes crispness due to a cool fragrance, is effective for constipation, diarrhea and motion sickness, and is also effective for sterilization and deodorization.

Since the above-mentioned peppermint oil is used in the composition of the mint flavor solution for improving digestion function according to the present invention, the deodorizing effect for removing the unique flavor of the herb medicine which decreases the sense of drinking is increased, and a refreshing feeling of drinking The effect becomes larger.

If the amount of the peppermint oil is less than 200 parts by weight, the effect described above may be deteriorated. If the amount of the peppermint oil is more than 250 parts by weight, irritation or itching may be caused .

The peppermint essence and the natural lime oil are also used together with the peppermint oil in the composition of the mint refreshing solution for improving digestion function according to the present invention to increase the deodorizing effect of removing the fragrance peculiar to the medicinal product, The effect of improving the feeling of drinking is increased due to the cool fragrance and the lime fragrance.

Preferably, the natural lime oil contains 50 to 100 parts by weight of the natural lime oil. If the natural lime oil is contained in an amount less than the above range, the above-described effect may be deteriorated, Excessive inclusion may cause irritation or itching.

Eucalyptus oil is extracted from eucalyptus tree, and is effective for sterilization and preservation, and also has a refreshing effect due to its clear fragrance.

Since the eucalyptus oil is used for the composition of the mint serum solution for improving digestion function according to the present invention, not only the effect of sterilization but also the effect of inducing refreshing drinking feeling due to the clear flavor is increased.

If the amount of the eucalyptus oil is less than 10 parts by weight, the effect described above may be deteriorated. If the amount of the eucalyptus oil is more than 50 parts by weight, the recommended amount of the eucalyptus oil may be exceeded.

[Mixing step (S60)]

The mixing step (S60) is a step of mixing the hot water extract solution dissolved in the first dissolving step and the second dissolving step and the menthol dissolving solution.

In the mixing step (S60), it is preferable to mix 0.05 to 1 part by weight of the menthol solution per 100 parts by weight of the hot water extract. If less than 0.05 part by weight of the menthol solution is mixed, the effect of the menthol dissolution solution may be deteriorated. If they are mixed in excess, the content of the hot water extract to be mixed becomes relatively low, which may be irritating or itching may occur, and the recommended intake may be exceeded.

[Charging process (S70)]

The charging step S70 is a step of performing the mixing step (S60) and filling the mixture with the carbonic acid gas into the vessel.

The carbon dioxide is carbon dioxide in a gaseous state. The carbon dioxide gas is charged together with the mixed liquid by performing the mixing process (S60), and the carbon dioxide gas having a weak acidity decomposes the food, And a refreshing sensation is obtained when drinking the mint water solution for improving the digestion function according to the present invention.

Best Mode for Carrying Out the Invention Hereinafter, embodiments of the mint liquid solution for improving digestion function and the method for producing the same according to the present invention will be described in detail.

[ Honor  One]

1 g of dermis, 0.5 g of health, and 0.5 g of broiler were added to the extractor, and 67 g of purified water was added thereto. The resulting mixture was heated at 95 ° C for 2 hours to extract the hot water extract and filtered to obtain 42 g ≪ / RTI >

To the extracted hot water extract solution were further mixed 60 mg of citric acid hydrate, 160 mg of sodium citrate hydrate and 30 mg of sodium chloride, 6 g of high fructose, 40 mg of stevioside (purity 50%) and 43 mg of sodium benzoate to obtain a first dissolving solution .

Further, 4 mg of L-menthol is mixed with 40 mg of ethanol as a solvent to prepare a second dissolution solution.

Then, the prepared first dissolving liquid and the second dissolving liquid were mixed to prepare a mint liquid solution for improving digestion function according to the present invention.

[ Honor  2]

1.5 g of dermis, 0.75 g of health and 0.75 g of broiler chickens were added to the extractor, and 67 g of purified water was added thereto. The resulting mixture was heated at 125 ° C. for 1 hour to extract the hot water extract, 45 g.

To the extracted hot water extract solution were further mixed 60 mg of citric acid hydrate, 160 mg of sodium citrate hydrate and 30 mg of sodium chloride, 6 g of high fructose, 40 mg of stevioside (purity 50%) and 43 mg of sodium benzoate to obtain a first dissolving solution .

In addition, a second dissolving liquid is prepared by mixing 6 mg of L-menthol, 90 mg of peppermint oil, 75 mg of peppermint essence, 30 mg of natural lime oil, and 5 mg of eucalyptus oil with 40 mg of ethanol as a solvent.

Then, the prepared first dissolving liquid and the second dissolving liquid were mixed to prepare a mint liquid solution for improving digestion function according to the present invention.

[ Honor  3]

Three grams of dermis, 1.5g of health, and 1.5g of broiler chickens were added to the extractor, and 67g of purified water was added. The hot water extract was extracted by heating at 125 ° C for 1 hour and filtered to obtain 47g ≪ / RTI >

To the extracted hot water extract solution were further mixed 50 mg of citric acid hydrate, 130 mg of sodium citrate hydrate and 20 mg of sodium chloride, 4 g of high fructose, 50 mg of stevioside (50% purity) and 35 mg of sodium benzoate to obtain a first dissolving solution .

Further, a second dissolving liquid is prepared by mixing 8 mg of L-menthol, 100 mg of peppermint oil, 80 mg of peppermint essence, 40 mg of natural lime oil and 10 mg of eucalyptus oil with 40 mg of ethanol as a solvent.

Then, the prepared first dissolving liquid and the second dissolving liquid were mixed to prepare a mint liquid solution for improving digestion function according to the present invention.

[ Honor  4]

6 g of dermis, 3 g of health, and 3 g of broiler were added to the extractor, 67 g of purified water was added, and the mixture was heated at 125 ° C. for 1 hour to extract the hot water extract, which was filtered to obtain 51 g of hot water extract .

In addition, to the extracted hot water extract solution, 60 mg of citric acid hydrate, 140 mg of sodium citrate hydrate and 30 mg of sodium chloride were further mixed with 5 g of high fructose, 50 mg of stevioside (50% purity) and 40 mg of sodium benzoate to obtain a first dissolving solution .

In addition, a second solution is prepared by mixing 2 mg of L-menthol, 80 mg of peppermint oil, 60 mg of peppermint essence, 35 mg of natural lime oil, and 8 mg of eucalyptus oil with 40 mg of ethanol as a solvent.

Then, the prepared first dissolving liquid and the second dissolving liquid were mixed to prepare a mint liquid solution for improving digestion function according to the present invention.

[ Example 1 ]

35 male ICR male rats aged 6 weeks old were purchased and fasted for 24 hours, and water was supplied in sufficient quantity.

Rats were randomly assigned to 5 rats in each of the four experimental groups (20 rats in each group, 5 rats in each group) in the experimental group, the non-rats treated with saline alone in the rats in Group 1, (Group 1, group 2) and group 4 (group 4) were administered with the control drug, methoclopride (Sigma-Aldrich). Respectively.

After the oral administration of 50 mg / kg of the corresponding substance in each experimental group, 5% Evans blue was orally administered to the digestive tract after 30 minutes, and 30 minutes later, the cervical vertebra was disassembled and the abdomen of the rat was divided into the midline The incision was made and the pylorus was removed from the upper pylorus to the rectum so as not to cut the intestine.

The distance (A) from the pylorus to the tip of Evans blue (5%) was measured, the distance from the pyloric to the rectum (B) was measured, and the percentage of digestive tract T (%) was calculated using the formula (A / B) x 100, and the results are shown in Table 1 below.

[Table 1]

As shown in Table 1, in the group 3 of the experimental group administered with the present invention, compared with the group 1 of the experimental group treated with saline and the group 2 treated with hot water extract of raw fish, And it was confirmed that there was an effect almost equal to or superior to that of the experimental group 4, which is a positive control group administered with methocloprid, which is a drug for promoting gastrointestinal motility, and that the main ingredient of the present invention, dermis, It was found that the intestinal tract was improved by the increase of the digestive tract moving rate T as the content increased.

[ Example 2 ]

35 male Sprague-Dawley (SD) male rats aged 6 weeks old were purchased and fasted for 24 hours, and water was supplied in sufficient quantity.

Rats were randomly assigned to 5 rats in each of the four experimental groups (20 rats in each group, 5 rats in each group) in the experimental group, the non-rats treated with saline alone in the rats in Group 1, In the group administered with hot-water extract of Phellinus linteus, Hwanggi, and Sein, group 3 of the experimental group, and group 4 of the experimental group, and group 4 of the control drug Mosapride (Sigma-Aldrich) .

After 30 minutes, the subject was orally administered 0.05% phenol red (Phenol red) 1.5 ml orally. After 20 minutes, the rat was overlaid under ether anesthesia, The stomachs were ligated and the stomach was removed to measure the amount of phenol red remaining in the stomach.

The extracted stomach was homogenized in 3 ml of 0.01 N NaOH, and then 0.2 ml of 20% trichloroacetic acid was added to 1 ml of the homogenate. The protein was precipitated and centrifuged at 1,600 g for 20 minutes. Then, 0.6 ml of supernatant , 0.8 ml of 0.5 N NaOH was added and the absorbance at 560 nm was measured. Gastric emptying (%) was calculated by the following equation, and it is shown in Table 2 below.

Gastric emptying rate GE (%) = [1- (phenol red absorbance measured 20 minutes after administration of phenol red / phenol red absorbance measured immediately after administration of phenol red)] × 100

[Table 2]

As shown in the above Table 2, in the group 3 of the experimental group administered with the present invention, the gastric emptying rate GE of the experimental group 1 and the group 2 of the experimental group treated with the hot water extract of raw fish, And it was confirmed that there was an effect almost equal to or superior to that of the experimental group 4, which is a positive control group administered with the simpuride, which is a therapeutic agent for functional dyspepsia, and the effect of the present invention on dermis, As the content increased, the gastric emptying rate was increased, so that it showed excellent gastric emptying ability, which proved to be effective in functional digestion failure.

As a result, the mint juice solution for improving the digestion function according to the present invention and the method for producing the mint juice solution according to the present invention have gentle stimulation to the mucous membranes of the digestive tract and gastrointestinal tract by the efficacy and pharmacological action of the herbal medicine contained in the mint juice solution, , Stimulates digestion by activating intestinal interlocking action, suppresses gastrointestinal spastic pain, anti-gastric ulcer action is possible, as well as menthol dissolving liquid is added to eliminate nasty digestion, It is possible to obtain a refreshing drinking feeling at the same time as removing it.

The present invention is not limited to the above-described embodiments. Anything having substantially the same constitution as the technical idea described in the claims of the present invention and achieving the same operational effect is included in the technical scope of the present invention.

Claims (17)

Hot-water extracts of herbal medicines including dermis, health and broiler; And menthol dissolving solution in which L-menthol is dissolved in ethanol. The menthol dissolving solution is mixed with 0.05 to 1 part by weight per 100 parts by weight of the filtered hot water extract,
The menthol solution contains 5 to 20 parts by weight of L-menthol, 200 to 250 parts by weight of peppermint oil, 150 to 200 parts by weight of peppermint essence, 50 to 100 parts by weight of natural lime oil and 10 to 50 parts by weight of eucalyptus oil per 100 parts by weight of ethanol Which is characterized in that it contains the mint juice solution for improving the digestive function with good sound feel.
The method according to claim 1,
The hot-water extract solution is prepared by adding 0.5 to 10 parts by weight of dermis, 0.1 to 5 parts by weight of health, and 0.1 to 5 parts by weight of broth to an extractor per 100 parts by weight of purified water, and heating to extract the mint serum solution .
The method according to claim 1,
The hot-water extract solution is prepared by adding a herbal medicine containing dermis, health, and broiler to an extractor, adding purified water thereto, and heating and filtering the mint extract.
delete The method of claim 3,
Wherein 0.1 to 1 part by weight of a mating agent, 5 to 15 parts by weight of a sweetener and 0.01 to 0.15 part by weight of a preservative are further mixed per 100 parts by weight of the filtered hot water extract solution.
6. The method of claim 5,
Wherein the mating agent comprises citric acid hydrate, sodium citrate hydrate and sodium chloride, wherein the sweetener comprises stevioside and high fructose, and the preservative is sodium benzoate.
delete delete A weighing process for weighing the materials;
An extracting step for extracting the hot water extract solution by adding the crude herbal medicine containing the dermis, health and broiler to an extractor, adding purified water, heating at 90 to 100 ° C for 1.5 to 2.5 hours, or heating at 120 to 130 ° C for 0.5 to 1.5 hours ;
A filtration step of filtering the extracted hot water extraction liquid;
A first dissolving step of further mixing and dissolving a mating agent, a sweetener and a preservative in the filtered hot water extract solution;
5 to 20 parts by weight of L-menthol, 200 to 250 parts by weight of peppermint oil, 150 to 200 parts by weight of peppermint essence, 50 to 100 parts by weight of natural lime oil and 10 to 50 parts by weight of eucalyptus oil per 100 parts by weight of ethanol are added to ethanol, A second dissolving step of dissolving the menthol solution to make a menthol dissolving solution; And
And a mixing step of mixing 0.05 to 1 part by weight of the menthol solution dissolved from the second dissolution step per 100 parts by weight of the hot water extract solution dissolved from the first dissolution step, ≪ / RTI >
10. The method of claim 9,
Wherein the extracting step is performed by adding 0.5 to 10 parts by weight of dermis, 0.1 to 5 parts by weight of health, and 0.1 to 5 parts by weight of broth to an extractor per 100 parts by weight of purified water, and heating to extract the mint serum solution ≪ / RTI >
delete 10. The method of claim 9,
Wherein the first dissolving step further comprises mixing and dissolving 0.1 to 1 part by weight of a mating agent, 5 to 15 parts by weight of a sweetener, and 0.01 to 0.15 part by weight of a preservative per 100 parts by weight of the filtered hot water extract, (Method for manufacturing mint name liquid for improvement of function).
13. The method of claim 12,
Wherein the mating agent comprises citric acid hydrate, sodium citrate hydrate and sodium chloride, wherein the sweetener comprises stevioside and high fructose, and the preservative is sodium benzoate. Gt;
delete delete delete 10. The method of claim 9,
And a filling step of filling the container with the carbonic acid gas after performing the mixing step.

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