KR101463213B1 - Manufacturing method for pill containing ingredient of leech saliva - Google Patents

Manufacturing method for pill containing ingredient of leech saliva Download PDF

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Publication number
KR101463213B1
KR101463213B1 KR20140018849A KR20140018849A KR101463213B1 KR 101463213 B1 KR101463213 B1 KR 101463213B1 KR 20140018849 A KR20140018849 A KR 20140018849A KR 20140018849 A KR20140018849 A KR 20140018849A KR 101463213 B1 KR101463213 B1 KR 101463213B1
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KR
South Korea
Prior art keywords
leeches
weight
honey
parts
glutinous rice
Prior art date
Application number
KR20140018849A
Other languages
Korean (ko)
Inventor
임재선
한선대
한승민
Original Assignee
임재선
한선대
한승민
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Application filed by 임재선, 한선대, 한승민 filed Critical 임재선
Priority to KR20140018849A priority Critical patent/KR101463213B1/en
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Publication of KR101463213B1 publication Critical patent/KR101463213B1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals

Abstract

The present invention relates to a method for preparing a pill with enhanced functionality containing ingredient of leech saliva, wherein the pill is prepared by using leeches such as Hirudo Verbana or Hirudinaria Manillensis which are used for medicinal or cosmetic purpose. To achieve the purpose, the method for preparing a pill containing ingredient of leech saliva according to the present invention is characterized by comprising: (a) drying leeches starved for 90 to 120 days for enabling intake of saliva of leeches to have 5 to 10 wt% of water content and pulverizing the resultant to 50 to 100 mesh; (b) homogeneously mixing 50 to 75 parts by weight of honey having 15 to 20 wt% of water content and 1 to 5 parts by weight of glutinous rice flour with respect to 100 parts by weight of the pulverized leeches; (c) storing the homogeneously mixed leeches, honey, and glutinous rice flour in a shady place by using a glass or ceramic container for 1 to 2 hours to minimize an influence of external factors; (d) preparing a mixture in which leeches, honey, and glutinous rice flour are homogeneously mixed to a pill with a diameter of 3 to 4 mm containing ingredient of leech saliva; and (e) commercializing the prepared pill containing ingredient of leech saliva by bottling.

Description

Technical Field [0001] The present invention relates to a method for manufacturing a leech ring,

More particularly, the present invention relates to a method for manufacturing a leech lehr having improved functionality, which is manufactured using leeches used for medical and cosmetic purposes such as Hirudo Verbana or Hirudinaria Manillensis.

The leech is a long, flat, loose and wrinkled hermaphrodite. In the Oriental medicine, it is caught between summer and fall, and is put into the lime. It is dried in the sun or fire and used for menopause, bruise, I was prescribed for symptoms. Leeds have been used to extract blood from swollen parts when they are shot or bitten by poisoned animals. Currently, leeches are used for medical purposes to prevent blood clots (blood clots) from clotting during surgical operations such as fingers and ears that have been cut by accident or during surgery such as plastic surgery. Blood clots can be easily removed by attaching clean leeches, cultured in aseptic conditions, to the area where the blood is gathered. In this process, pain is rarely caused by the anesthetic component secreted from the salivary gland.

Hirudo Verbana or Hirudinaria Manillensis contains more than 100 physiologically active substances in leech saliva, including Leech Derived Tryptase Inhibitor (LDTI), which is unique to leech, A cholinergic agent, a cholinesterase, a dexamethasone, a carnitine, a dexamethasone, a dexamethasone, a dexamethasone, And acetylcholine, were verified by a two-plane electrophoresis test.

As seen from the above, leeches containing ingredients beneficial to the human body were conventionally used only for medical purposes, and they were not able to directly ingest them. That is, it is known from the prior art of Korean Patent No. 10-0137519 (registered date: 1998. 02. 10.) and Korean Patent Laid-open No. 10-2002-56211 (published date: 2002. 07. 10.) As described above, only a part beneficial to the human body is extracted from the leeches, and the technique of directly ingesting beneficial ingredients in the body including saliva saliva is insufficient. Korean Registered Patent No. 10-114827 (Registration Date: 2012. 02. 03.) and No. 10-1313543 (Registration Date: Sep. 25, 2013. 09) The present invention relates to a method for producing a ring containing epidermis and a method for producing the same, and a method for producing a ring using a saccharified red pepper, It is true.

KR 10-0137519 B1 1998. 02. 10. KR 10-2002-56211 A 2002. 07. 10. KR 10-0137519 B1 1998. 02. 10. KR 10-1313543 B1 2013. 09.25.

Disclosure of Invention Technical Problem [8] The present invention has been made in order to solve the problems of the prior art described above, and it is an object of the present invention to provide a lee used for medical and cosmetic purposes, And to a method for manufacturing a giraffe ring.

In order to accomplish the above object, the present invention provides a method of manufacturing a leech pie ring comprising: (a) drying leeches in a hungry state for 90 to 120 days at a moisture content of 5 to 10% by weight and pulverizing the leeches to 50 to 100 mesh; (b) uniformly mixing 50 to 75 parts by weight of honey having a moisture content of 15 to 20% by weight and 1 to 5 parts by weight of glutinous rice powder with respect to 100 parts by weight of the ground leeches; (c) storing the leeches, honey and glutinous rice flour in a shaded place for 1 to 2 hours; (d) preparing a mixed mixture of leeches, honey, and glutinous rice flour as a germanic ring having a diameter of 2 to 5 mm; And (e) feeding the produced giraffe ring into a commercial product.

INDUSTRIAL APPLICABILITY According to the present invention, it is possible to ingest a beneficial ingredient contained in leeches to the skin, thereby improving palatability to leeches.

Also, according to the present invention, it is possible to contribute to the increase of income of the farm household through the mass proliferation of leeches for the production of leeches.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a sequence diagram showing the flow of a method for manufacturing a girdle ring according to the present invention; FIG.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings.

1 is a flowchart showing the flow of a method for manufacturing a giraffe ring according to the present invention. The present invention comprises a leeches liquid pulverization step, a mixing step, a storage step and a commercialization step.

According to the present invention, firstly leeches which are hungry for 90 to 120 days are dried at a water content of 5 to 10% by weight and then pulverized to 50 to 100 mesh.

The leeches used in the present invention are those that have been crushed to a size of 50 to 100 mesh. When leeches ground less than 50 meshes are used, the chewiness of the leeches is strong, which is undesirable. When the leeches that are crushed by more than 100 meshes are used, the chewiness of the leeches is weak and the taste of the leeches is not felt.

In addition, the leech powder is used for 90 to 120 days after the starch leech is dried and then crushed. The leech has the characteristic of finding food again after 3 to 4 months after the blood is bloomed, and it holds the most saliva. Therefore, after feeding the leeches, the leeches after 3 ~ 4 months when the saliva is most secreted are dried and crushed.

That is, in the present invention, the leech in the hungry state is pulverized by being dried for 90 to 120 days so that the saliva containing the components beneficial for the body can be directly ingested. The starved leech is dried to a moisture content of 5 to 10 wt% Crushed in the state. When the leeches which have a moisture content of less than 5% by weight are crushed, the leeches which are floated in the crushing process are not preferred because of the large amount of leeches which are lost. When the leeches are crushed by moisture content exceeding 10% by weight, This is not desirable because the leeches can not be crushed to the desired size.

After the leeches are crushed, 50 to 75 parts by weight of honey having a water content of 15 to 20% by weight and 1 to 5 parts by weight of glutinous rice flour are uniformly mixed with 100 parts by weight of crushed leeches. Honey is a living food because it has enzymes other than ideal ideal nutritional ingredients such as pollen-specific vitamins, proteins, minerals, aromatic substances and amino acids. It is excellent in the effect of restoring fatigue by glucose and fructose. According to the present invention, when honey is mixed with less than 50 parts by weight with respect to 100 parts by weight of crushed leeches, there is a problem that crushed leeches do not clump well due to lack of honey. In addition, when more than 75 parts by weight of honey is mixed with 100 parts by weight of the ground leeches, honey is excessively contained in comparison with leeches and the drying process becomes longer.

The glutinous rice flour used in the present invention may be pulverized to 50-200 mesh. Preferably, 400-400 parts by weight of water is added to 100 parts by weight of the glutinous rice flour milled to 50-200 mesh, 1 to 5 parts by weight of the batter may be used.

Here, the glutinous rice powder serves to bind the crushed leeches so that the ring shape having a constant diameter can be maintained. Glutinous rice powder is good for people with bad digestion and absorption, good for people with bad stomach, good for people whose stomach is poor digestion, rich in minerals and vitamins, and controlling unbalanced nutrients. It causes nausea, inhibits the development of colorectal cancer, and lowers blood cholesterol. In addition, good water retention, constipation and prevent insulin secretion, obesity, hypertension, arteriosclerosis and can prevent adult diseases.

In the present invention, glutinous rice flour is taken as an example, but the same function can be performed by using flour instead of glutinous rice flour.

After mixing the leeches, honey and glutinous rice flour together, mix the mixture for 1-2 hours in a shady place and let it mature. Even if mixed evenly, it may take a certain time for the honey to completely penetrate the leeches powder.

The storage container for the mixture used in the present invention is preferably a glass or ceramic container which can be less affected even when brought into contact with the mixture. When a container made of a material made of PVC, PE, or the like is used, the chemical reaction can be performed by contacting the material of the container with the mixture, which is not preferable.

When the leech liquor is aged for less than 1 hour, there is a problem that honey is not easy to impregnate into the crushed lee. In case of aging for more than 2 hours, honey is dropped to the bottom of the container, The mixing ratio of the mixture located at the upper part and the lower part is different.

The leach liquor of the present invention is aged in a shady place so that the aging process can be minimized by external factors such as the sun.

After the storage and aging of the mixture of leeches, honey and glutinous rice flour, the mixture is made into a germanic ring having a diameter of 2 to 5 mm. If the mixture is manufactured to a diameter of less than 2 mm, there is a side that is not easy to manufacture due to its small diameter, and if it is manufactured with a diameter exceeding 5 mm, it is not preferable because of the risk of getting throat upon ingestion. The diameter of the girdle ring is preferably 3 to 4 mm, so that it is preferable that the girdle ring has no difficulty in the manufacturing process and is safe even when ingested.

After the completion of the girdle ring, the completed leeches shall be fed into the market. The finished girdle ring can be put into various size containers for commercialization.

According to the present invention, since the beneficial ingredient contained in the leech can be ingested by the ring, there is an effect of improving the preference for the leech, and it is possible to contribute to the increase of the income of the farmer through the mass proliferation of leech .

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments, but, on the contrary, It will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (2)

(a) drying the leech in a hungry state for 90 to 120 days to 5 to 10% by weight in water content so as to be able to ingest the saliva saliva, and then pulverizing the leeches to 50 to 100 mesh;
(b) uniformly mixing 50 to 75 parts by weight of honey having a moisture content of 15 to 20% by weight and 1 to 5 parts by weight of glutinous rice powder with respect to 100 parts by weight of the ground leeches;
(c) storing in a shady place, using a glass or ceramic container with the leeches, honey and glutinous rice flour mixed evenly for 1 to 2 hours to minimize the effect of external factors;
(d) preparing a mixed mixture of leeches, honey, and glutinous rice flour into a german ring having a diameter of 3 to 4 mm; And
(e) incorporating the manufactured girder ring into a product;
The method of claim 1,
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KR20140018849A 2014-02-19 2014-02-19 Manufacturing method for pill containing ingredient of leech saliva KR101463213B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR20140018849A KR101463213B1 (en) 2014-02-19 2014-02-19 Manufacturing method for pill containing ingredient of leech saliva

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Application Number Priority Date Filing Date Title
KR20140018849A KR101463213B1 (en) 2014-02-19 2014-02-19 Manufacturing method for pill containing ingredient of leech saliva

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101178475B1 (en) * 2012-04-02 2012-09-06 김병구 Manufacturing method of blood circulation improvement and ache mitigator

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101178475B1 (en) * 2012-04-02 2012-09-06 김병구 Manufacturing method of blood circulation improvement and ache mitigator

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