KR101276463B1 - 수지 상 펩티드 고리화 - Google Patents

수지 상 펩티드 고리화 Download PDF

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Publication number
KR101276463B1
KR101276463B1 KR1020127016164A KR20127016164A KR101276463B1 KR 101276463 B1 KR101276463 B1 KR 101276463B1 KR 1020127016164 A KR1020127016164 A KR 1020127016164A KR 20127016164 A KR20127016164 A KR 20127016164A KR 101276463 B1 KR101276463 B1 KR 101276463B1
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KR
South Korea
Prior art keywords
peptide
solid phase
resin
reaction
coupling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020127016164A
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English (en)
Korean (ko)
Other versions
KR20120088855A (ko
Inventor
스테판 바라이
올레크 베르비츠키
토마스 차이터
Original Assignee
론자 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 론자 아게 filed Critical 론자 아게
Publication of KR20120088855A publication Critical patent/KR20120088855A/ko
Application granted granted Critical
Publication of KR101276463B1 publication Critical patent/KR101276463B1/ko
Assigned to 폴리펩티드 레브러토리즈 홀딩 (피피엘) 에이비 reassignment 폴리펩티드 레브러토리즈 홀딩 (피피엘) 에이비 권리의 전부이전등록 Assignors: 론자 아게
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyamides (AREA)
KR1020127016164A 2004-10-19 2005-10-18 수지 상 펩티드 고리화 Expired - Fee Related KR101276463B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP04024813 2004-10-19
EP04024813.0 2004-10-19
EP05008979 2005-04-25
EP05008979.6 2005-04-25
PCT/EP2005/011182 WO2006045483A2 (en) 2004-10-19 2005-10-18 On-resin peptide cyclization

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020077010506A Division KR101222774B1 (ko) 2004-10-19 2005-10-18 수지 상 펩티드 고리화

Publications (2)

Publication Number Publication Date
KR20120088855A KR20120088855A (ko) 2012-08-08
KR101276463B1 true KR101276463B1 (ko) 2013-06-19

Family

ID=36096370

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020127016164A Expired - Fee Related KR101276463B1 (ko) 2004-10-19 2005-10-18 수지 상 펩티드 고리화
KR1020077010506A Expired - Fee Related KR101222774B1 (ko) 2004-10-19 2005-10-18 수지 상 펩티드 고리화

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020077010506A Expired - Fee Related KR101222774B1 (ko) 2004-10-19 2005-10-18 수지 상 펩티드 고리화

Country Status (16)

Country Link
US (1) US7994280B2 (https=)
EP (1) EP1805203B1 (https=)
JP (1) JP4927746B2 (https=)
KR (2) KR101276463B1 (https=)
CN (1) CN101111510B (https=)
AT (1) ATE455123T1 (https=)
AU (1) AU2005298991B2 (https=)
BR (1) BRPI0516929A (https=)
CA (1) CA2588098A1 (https=)
DE (1) DE602005018952D1 (https=)
DK (1) DK1805203T3 (https=)
ES (1) ES2339791T3 (https=)
IL (1) IL182575A (https=)
PT (1) PT1805203E (https=)
TW (1) TW200628487A (https=)
WO (1) WO2006045483A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101538316B (zh) * 2009-01-13 2012-09-05 深圳翰宇药业股份有限公司 一种固相法制备Eptifibatide的方法
WO2013112548A1 (en) * 2012-01-23 2013-08-01 University Of South Florida Gamma-aapeptides with potent and broad-spectrum antimicrobial activity
CN108218964A (zh) * 2018-01-30 2018-06-29 江南大学 一种固相载体上酶法合成环肽方法
CN121194984A (zh) * 2023-05-18 2025-12-23 港大科桥有限公司 形成二硫键模拟物的后期肽环化

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003093302A2 (en) * 2002-05-03 2003-11-13 Avecia Limited Process for the synthesis of peptides amides by side-chain attachement to a solid phase
CN1500805A (zh) * 2002-11-14 2004-06-02 吉尔生化（上海）有限公司 一种制备依非巴特的新工艺
WO2005121164A1 (en) 2004-06-14 2005-12-22 Usv Limited Process for the preparation of peptides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4606856A (en) * 1985-03-18 1986-08-19 Seyler Jay K [Des-1-amino, 8-glycine]calcitonin
US5770687A (en) * 1995-06-07 1998-06-23 Peptor Limited Comformationally constrained backbone cyclized somatostatin analogs
DE04759123T1 (de) 2003-04-07 2005-08-18 Novetide Ltd. Verfahren zur herstellung cyclischer peptide
CN100500805C (zh) * 2006-11-07 2009-06-17 武汉钢铁集团鄂城钢铁有限责任公司 除尘焦粉回配煤炼焦方法及其工艺

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003093302A2 (en) * 2002-05-03 2003-11-13 Avecia Limited Process for the synthesis of peptides amides by side-chain attachement to a solid phase
CN1500805A (zh) * 2002-11-14 2004-06-02 吉尔生化（上海）有限公司 一种制备依非巴特的新工艺
WO2005121164A1 (en) 2004-06-14 2005-12-22 Usv Limited Process for the preparation of peptides

Also Published As

Publication number Publication date
IL182575A0 (en) 2007-07-24
EP1805203A2 (en) 2007-07-11
US20080200647A1 (en) 2008-08-21
DK1805203T3 (da) 2010-05-17
PT1805203E (pt) 2010-04-19
JP2008517016A (ja) 2008-05-22
JP4927746B2 (ja) 2012-05-09
WO2006045483A3 (en) 2006-07-13
US7994280B2 (en) 2011-08-09
KR101222774B1 (ko) 2013-01-15
ATE455123T1 (de) 2010-01-15
CN101111510B (zh) 2011-09-14
EP1805203B1 (en) 2010-01-13
AU2005298991B2 (en) 2011-03-03
WO2006045483A2 (en) 2006-05-04
CA2588098A1 (en) 2006-05-04
AU2005298991A1 (en) 2006-05-04
BRPI0516929A (pt) 2008-09-23
KR20120088855A (ko) 2012-08-08
TW200628487A (en) 2006-08-16
ES2339791T3 (es) 2010-05-25
IL182575A (en) 2012-07-31
DE602005018952D1 (de) 2010-03-04
KR20070084099A (ko) 2007-08-24
CN101111510A (zh) 2008-01-23

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