KR101240698B1 - Liquid detergent composition for clothes - Google Patents

Abstract

The present invention,

(A) polyoxyethylene alkyl ether;

(B) the following general formula (I):

(Wherein X, Y and Z are hydrogen atoms, C _n H _{2n +1} or (CH ₃ ) ₂ CH (wherein n is an integer of 1 to 3), and M is a hydrogen atom, an alkali metal atom, an alkali) Earth metal atoms, NH ^{4 +} or alkanolamines);

(C) semi-polar surfactant, amphoteric surfactant, or the following general formula (II) or (III):

(In formula, R <^11> , R <^12> , R <^13> represents an alkyl group, an alkenyl group, a linear hydroxyalkyl group, a tolyl group, a phenyl group, or a benzyl group, EO represents an ethylene oxide group, and a and b respectively represent 0 or more A + b represents 10 or more, and X ⁻ represents anion; And

(D) 1-hydroxyethane-1,1-diphosphonic acid or its salt;

It relates to a medical liquid detergent composition comprising a.

Medical Liquid Cleanser

Description

Medical Liquid Cleanser Composition {LIQUID DETERGENT COMPOSITION FOR CLOTHES}

The present invention relates to a liquid liquid detergent composition.

This application claims priority based on Japanese Patent Application No. 2005-269972 for which it applied on September 16, 2005, and uses the content here.

Background Art Conventionally, in medical liquid detergent compositions, high cleaning power against contamination that is difficult to drop, such as onion salt, is required.

As a conventional medical liquid detergent composition, Patent Documents 1 and 2, for example, each contain an acid having, as a main component, at least one surfactant selected from amine oxides and amphoteric surfactants for the purpose of cleaning blackish contamination. Disclosed are a laundry pretreatment composition and an acid coating detergent composition.

Patent Document 3 discloses a laundry pretreatment composition containing one or more surfactants selected from amine oxides and amphoteric surfactants and organic acids and inorganic acids of pKa 2.0 to 6.8, for the purpose of cleaning darkening contamination. .

Patent document 4 describes a medical liquid detergent composition containing a specific amphoteric surfactant and a nonionic (nonionic) surfactant.

Patent document 5 describes a pretreatment agent for onion salt which consists of an acidic composition containing a compound having a phosphonic acid group.

Patent Literature 6 discloses a cleaning composition in which a plurality of specific surfactants are combined for the purpose of cleaning stubborn contamination.

Patent Literature 7 discloses a medical liquid detergent composition using a specific non-ionic surfactant for the purpose of satisfying both touch and detergency without any objectionability.

In patent document 8, polyoxyethylene alkyl ether whose alkyl group is C10-20 and the average added mole number of ethylene oxide is 8-26 (henceforth this component may be called "a specific nonionic surfactant." ) And / or polyoxyethylene alkyl ether sulfate having an alkyl group of 10 to 20 carbon atoms and an average added mole number of ethylene oxide of 1 to 5, and 1-hydroxyethane-1,1 as a metal ion supplement A composition in which diphosphonic acid or a salt thereof is blended is disclosed.

Patent Document 1: Japanese Patent Application Laid-Open No. 2000-109889

Patent Document 2: Japanese Patent Application Laid-Open No. 2000-109893

Document 3: Japanese Patent Application Laid-Open No. 2000-109890

Patent Document 4: Japanese Patent Application Laid-Open No. 08-157870

Patent Document 5: Japanese Patent Application Laid-Open No. 3-26797

Patent Document 6: Japanese Patent No. 3556806

Patent Document 7: Japanese Patent No. 2813112

Patent Document 8: Japanese Patent Application Laid-Open No. 2004-210961

However, in the compositions described in Patent Literatures 1 and 2, since only the main component is an amphoteric surfactant, the cleaning effect on the onio salt is not satisfactory.

Moreover, in the composition of patent document 3, the washing | cleaning effect of an onion salt is not enough.

Also in the composition of patent documents 4-8, the washing | cleaning effect with respect to onion salt is not satisfying.

Then, this invention makes it a subject to provide the medical liquid detergent composition which has favorable washing | cleaning power with respect to onion salt and sebum contamination.

The present invention,

(A) 2-50 mass% of polyoxyethylene alkyl ethers whose carbon number of a hydrophobic group is 10-20, and the average added mole number of ethylene oxide is 3-26;

(B) the following general formula (I):

(Wherein X, Y and Z are each independently a hydrogen atom, C _n H _{2n +1} or (CH ₃ ) ₂ CH (wherein n is an integer of 1 to 3), and M is a hydrogen atom or an alkali metal atom) , An alkaline earth metal atom, NH ⁴⁺ or an alkanolamine;

(C) Semi-polarizing surfactant, amphoteric surfactant, and the following general formula (II) or (III):

(In the formula, R ^11, RR ¹² is, independently, a represents any of a carbon number of 1 to 20 linear or branched chain alkyl group or alkenyl group, a straight-chain hydroxyalkyl group, a tolyl group, a phenyl group, a benzyl group, R ¹³ Silver represents any of C8-C20 linear or branched alkyl group or alkenyl group, linear hydroxyalkyl group, tolyl group, phenyl group, benzyl group, EO represents an ethylene oxide group, a, b are each 0 or more At least one compound selected from the group consisting of compounds represented by a + b represents 10 or more and X ⁻ represents anion; And

(D) 1-hydroxyethane-1,1-diphosphonic acid or its salt,

It relates to a medical liquid detergent composition comprising a.

The medical liquid detergent composition,

(E) Monoethanolamine may also be contained.

In this invention, the medical liquid detergent composition which has favorable washing | cleaning power with respect to onion salt can be provided.

(A) Component

(A) component has 2 to 50 mass% of polyoxyethylene alkyl ethers of 10-20 carbon atoms and 3 to 26 average added mole numbers of ethylene oxide of a hydrophobic group (alkyl group).

The carbon number of the alkyl group is preferably 11 or more, more preferably 12 or more, and the upper limit is preferably 18 or less, particularly 15 or less, in terms of onion salt detergency. In addition, in 1 mol of component (A), the lower limit of the average added mole number of ethylene oxide is preferably 5 or more, more preferably 8 or more, and the upper limit of 20 or less, More preferably, it is 18 or less.

The component (A) is a nonionic surfactant, and may be obtained by addition reaction of ethylene oxide to a higher alcohol by a conventional method using an alkali catalyst or the like, or a commercial item may be used.

Examples of the higher alcohols include straight chain primary alcohols, branched primary alcohols, and straight chain secondary alcohols.

(A) component can be used 1 type or in mixture of 2 or more types.

The compounding quantity of (A) component is 2-50 mass% in the medical liquid detergent composition. Preferably it is 10-50 mass%, More preferably, it is 15-45 mass%, Especially preferably, it is the range of 20-40 mass%. When the compounding quantity of (A) component exists in this range, the washing | cleaning power of onion salt will improve. In addition, the cleaning power and liquid stability (characteristics of maintaining a stable state without gelation or the like) of sebum contamination are improved.

Component (B)

(B) A component is a compound represented by general formula (I).

Wherein, X, Y, Z are each independently H, C _n H _{2n +1} or (CH _{3) 2} CH and (n is an integer of 1 to 3. In the formula), preferably CH _3.

M is a hydrogen atom; Alkali metal atoms such as sodium and potassium; Alkaline earth metal atoms such as magnesium and calcium; NH ^{4 +} ; Or alkanolamines such as monoethanolamine, diethanolamine, and triethanolamine, and preferably sodium, monoethanolamine and diethanolamine.

Examples of specific compounds include benzene sulfonic acid, benzene sulfonic acid sodium salt, benzene sulfonic acid potassium salt, benzene sulfonic acid ammonium salt, benzene sulfonic acid magnesium salt, benzene sulfonic acid calcium salt, benzene sulfonic acid monoethanolamine salt, benzene sulfonic acid diethanolamine salt, and benzene sulfonic acid triethanolamine Salt, p-toluenesulfonic acid salt, p-toluenesulfonic acid sodium salt, p-toluenesulfonic acid potassium salt, p-toluenesulfonic acid ammonium salt, p-toluenesulfonic acid magnesium salt, p-toluenesulfonic acid salt, p-toluenesulfonic acid monoethanolamine salt, p-toluenesulfonic acid diethanolamine salt, p-toluenesulfonic acid triethanolamine salt, 0- or m- or p-xylenesulfonic acid, 0- or m- or p-xylenesulfonic acid sodium salt, 0- or m- or p-xylene Potassium sulfonic acid salt, 0- or m- or p-xylenesulfonic acid ammonium salt, 0- or m- or p-xylenesulfonic acid magnesium salt, 0- or m- or p-xylenesulfonic acid calcium salt, 0- or m- or p- Big Rensulfonic acid monoethanolamine salts, 0- or m- or p-xylenesulfonic acid diethanolamine salts, 0- or m- or p-xylenesulfonic acid triethanolamine salts, cumenesulfonic acid, cumenesulfonic acid sodium salts, cumenesulfonic acid potassium salts, Cumene sulfonate ammonium salt, cumene sulfonate magnesium salt, cumene sulfonic acid calcium salt, cumene sulfonic acid monoethanolamine salt, cumene sulfonic acid diethanolamine salt, cumene sulfonic acid triethanolamine salt, and the like.

Among them, p-toluenesulfonic acid, m-xylenesulfonic acid, cumenesulfonic acid or monoethanolamine salts thereof are preferable.

(B) A component can be used 1 type or in mixture of 2 or more types.

The compounding quantity of (B) component becomes like this. Preferably it is 1-15 mass%, More preferably, it is 3-10 mass%, Especially preferably, it is the range of 3-6 mass%. When (B) component exists in this range, the washing | cleaning power of onion salt will improve. Moreover, since it is excellent in storage stability, it is preferable.

(C) Component

(C) component is a semipolar surfactant, an amphoteric surfactant, and General formula (II):

Compound represented by the formula and general formula (III):

It is at least 1 sort (s) of compound chosen from the group which consists of a compound represented by these.

As said semipolar surfactant, the amine oxide type surfactant etc. which are represented by following General formula (IV) are mentioned, for example.

[Formula 2]

(Wherein R ¹ is a C8-18, preferably 8-16, more preferably 10-14, straight or branched alkyl or alkenyl group, R ² , R ³ are each independently and C 1 An alkyl group or a hydroxyalkyl group of 3 to 3. R ⁴ is an alkyl group having 1 to 4 carbon atoms, and A is a group selected from -CO-NH-, -NHCO-, -COO-, -OCO-, or -O- N 'is 0 or 1).

Specifically, alkyldimethylamine oxide, alkylamidopropyldimethylamine oxide, etc. are mentioned, Preferably alkyldimethylamine oxide is preferable at the point of washing | cleaning power, Especially n-dodecyldimethylamine oxide is preferable. . For example, n-dodecyldimethylamine oxide is commercially available from Lion Akzo Co., Ltd., and the like.

As amphoteric surfactant, N-alkyl or alkenylamino acid or its salt, and betaine are mentioned, for example.

N-alkyl or alkenylamino acid has an alkyl group or an alkenyl group bonded to a nitrogen atom, and also one or two "-R-COOH" (wherein R represents a divalent hydrocarbon group, preferably an alkylene group, It is especially preferable that it is C1-C2), and the group couple | bonded has a structure. In the compound which "-R-COOH" couple | bonded with one, the hydrogen atom couple | bonded with the nitrogen atom further.

One of "-R-COOH" is called mono-body and two are called di-body. In (C) component, all of these mono- and di-body can be used.

In N-alkyl or alkenylamino acid, it is preferable that carbon number of an alkyl group and an alkenyl group is 10-20, These may be linear or branched. As a salt, it is preferable that they are alkali metal salts, such as sodium and potassium, and it is preferable that they are sodium salts.

Preferred examples include alkyl or alkenylaminopropionic acid or salts thereof, and laurylaminopropionic acid or sodium salts thereof is more preferable.

As a commercial item, lauryl amino propionic acid Na (made by Ippsha Yuji Co., Ltd.) etc. are mentioned, for example. This is a mixture of 90% by mass to 10% by mass of the mono and di bodies.

Examples of betaines include alkyl betaine, carbo betaine, amide betaine, sulfobetaine, amide sulfobetaine, imidazolinium betaine, phosphobetaine, and the like. Alkyl such as fatty acid amidepropyl betaine, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, alkyldimethylaminoacetate betaine, alkylhydroxysulfobetaine, lauryldimethylbetaine Dimethyl betaine etc. are mentioned.

As a commercial item, a lauric acid amide propyl betaine (brand name "Softazorine LPB"; product made by Saint-Jean Fine Chemicals Co., Ltd.), lauryl dimethyl betaine (brand name "Anhitol 24B"; Cao Co., Ltd. product) etc. Can be mentioned.

Among them, alkyl betaine, amide betaine and sulfobetaine are preferable, and lauric acid amidepropyl betaine and lauryl dimethyl betaine are particularly preferable.

Among the amphoteric surfactants, N-alkyl or alkenylamino acids or salts thereof are particularly preferred, and alkylbetaine, amidebetaine and sulfobetaine.

In the general formula (II), R ¹¹ and R ¹² are each independently any of a linear or branched alkyl group or alkenyl group, a long chain hydroxyalkyl group, a tolyl group, a phenyl group, or a benzyl group having 1 to 20 carbon atoms. Indicates.

Carbon number of an alkyl group becomes like this. More preferably, it is 10-18. The carbon number of the alkenyl group is particularly preferably 10 to 18.

In the long-chain hydroxyalkyl group, the carbon number of the alkyl group is preferably 10 to 20, particularly 10 to 18. The number of hydroxyl groups is 1-3, for example, Preferably it is 1.

Particularly preferably, one of R ^{11 and} R ¹² is a combination of a linear or branched alkyl group or alkenyl group having 10 to 18 carbon atoms, and the other is a combination of methyl group, tolyl group or benzyl group.

EO represents an ethylene oxide group. a and b respectively independently represent the average added mole number of ethylene oxide groups, and are each independently 0 or more.

Moreover, a + b is 10 mol or more, Preferably it is 10-50 mol. When a + b is 10 mol or more, the dispersion effect of the organic substance in sludge improves, and the washing | cleaning power with respect to sludge salt becomes favorable.

X ₁ ^- is anion, and a halogen atom ion such as chlorine ion, bromine ion, iodine ion or the general formula R ⁵ SO ₄ ^- (However, R ⁵ is C 1 -C 3 alkyl group (methyl group, ethyl group, propyl Ions), and particularly preferably a methyl group).

Examples of commercially available products, for example, itppo Shah maintained Industry Co., trade name "bis play UP-10" (R ^11,: tallow R ¹² (牛脂) alkyl group derived from (Carbon number 14 to 20): a benzyl group, a + ^{_{b = 30, X 1 -:}} Cl-) or lion-Akzo Co., Ltd. trade name "ETHOQUAD (Esso card) C / 25 '(R ^11,: alkyl groups derived from coconut oil (having a carbon number of 8 to 18), R ¹² A methyl group, a + b = 15, X < ₁ ^->- Cl-) i etc. are mentioned.

In said general formula (III), R <^13> is any of the C8-C20 linear or branched alkyl group or alkenyl group, long-chain hydroxyalkyl group, tolyl group, phenyl group, and benzyl group.

Carbon number of an alkyl group becomes like this. More preferably, it is 10-18. The carbon number of the alkenyl group is particularly preferably 10 to 18.

In the long-chain hydroxyalkyl group, the carbon number of the alkyl group is preferably 10 to 20, particularly 10 to 18. The number of hydroxy groups is 1 to 3, for example, Preferably it is 1.

In R ¹³ , Especially preferably, they are a C10-C18 linear or branched alkyl group or alkenyl group.

EO represents an ethylene oxide group. a and b are the average added mole numbers of ethylene oxide groups, and are each independently 0 or more. Moreover, a + b is 10 mol or more, Preferably it is 10-50 mol. When a + b is 10 or more, the dispersing effect of the organic matter in the sludge is improved, and the washing power against the sludge salt becomes good.

Examples of commercially available products, for example lion-Akzo Co., Ltd., trade name "ETHOMEEN (in Somin) C / 25 '(R ^13: alkyl group of palm oil-derived (having 8 to 18), a + b = 15), Lion, the (hardened beef tallow alkyl group derived from (Carbon number 14 to 20), a + b = 50 R 13), Lion-Akzo Co., Ltd., Akzo Co., Ltd., trade name "ETHOMEEN (in Somin) SA2Y-103" and the like: (hardened beef tallow alkyl group derived from (Carbon number 12 to 20), a + b = 10 R 13) trade name "ETHOMEEN (in Somin) SsAJ-103".

(C) component can be used 1 type or in mixture of 2 or more types.

The content of the component (C) is preferably 0.5 to 10% by mass and more preferably 0.5 to 5% by mass in the medical liquid detergent composition from the viewpoint of improving the cleaning power of the onion salt. Moreover, if it is this range, the washing | cleaning power with respect to sebum contamination will also improve.

Moreover, by setting it as 10 mass% or less, a rinse time becomes short, and also a formulation becomes easy, and it is more preferable.

(D) Component

Component (D) is 1-hydroxyethane-1,1-diphosphonic acid and / or its salt.

Examples of the salt include alkali metal salts such as sodium salts and potassium salts, alkanolamine salts such as monoethanolamine salts and diethanolamine salts.

Among these, 1-hydroxyethane-1,1-diphosphonic acid is preferable.

(D) component can be used 1 type or in mixture of 2 or more types.

Content of (D) component is 0.1-10 mass%, More preferably, it is 0.1-5 mass% in a medical liquid detergent composition from a viewpoint of onion salt cleaning power. When it is 0.1 mass% or more, the washing power of an onion salt improves, and when it is 10 mass% or less, (D) component can be mix | blended more stably. Moreover, it is also preferable at the point of the cleaning power improvement of sebum contamination.

(E) component

(E) component is monoethanolamine.

The compounding quantity of monoethanolamine is 0.1-20 mass% in a medical liquid detergent composition, Preferably it is 0.5-8 mass%, More preferably, it is 1-5 mass%. If it exists in this range, sebum stain and onion salt cleaning power will improve. Moreover, it becomes easy to adjust to the range of the preferable pH mentioned later, and storage stability improves, especially when it is stored long term (for example, 1 year or more) at high temperature (for example, 30-35 degreeC), storage stability It is excellent in, and generation | occurrence | production of precipitation etc. can be prevented.

As monoethanolamine, Japan Catalyst Co., Ltd. product and Mitsui Chemicals Co., Ltd. product are marketed, for example.

Any other ingredients

Nonionic surfactants and anionic surfactants other than (A) component can be mix | blended with the medical liquid detergent composition of this invention.

The nonionic surfactant has an alkyl group having 8 to 18 carbon atoms, an alkylpolyglucoside having an average added mole number of 1 to 10 of the glucose unit, an alkyl group having 8 to 18 carbon atoms, and an alkyl having an average added mole number of 1 to 3 glycerin units. Methoxy polyoxyethylene alkanoate having a glyceryl ether, a fatty acid diethanolamide having 10 to 20 carbon atoms, an alkyl group having 10 to 18 carbon atoms, and an average added mole number of 1 to 30 ethylene oxide, and the like.

As for the compounding quantity of nonionic surfactant other than these (A) component, the range of 0-10 mass% is preferable in a medical liquid detergent composition.

As an anionic surfactant, it has the alkylbenzenesulfonate which has a C8-C16 alkyl group, the alkyl sulfate which has a C10-C20 alkyl group, the C10-C2 alkyl group, and the average addition mole number of ethylene oxide of 1-10 Polyoxyethylene alkyl ether sulfate, a-olefin sulfonate having an alkyl group of 10 to 20 carbon atoms, alkane phosphate having an alkyl group of 10 to 20 carbon atoms, a-sulfo fatty acid methyl ester salt having an alkyl group of 10 to 20 carbon atoms, carbon number Polyoxyethylene alkyl ether carbonates having an alkyl group of 10 to 20 and an average added mole number 1 to 10 of ethylene oxide; and the like.

As for the compounding quantity of these anionic surfactant, the range of 0-10 mass% is preferable in a medical liquid detergent composition.

Other optional components can be mix | blended with the medical liquid detergent composition of this invention as needed.

Specifically, examples of the hydrotroping agent include glycol solvents such as ethylene glycol, propylene glycol, polyethylene glycol, and polypropylene glycol, alcohols such as ethanol, and the like. Among them, polyethylene glycol and ethanol having a mass average molecular weight of 400 to 5000 are preferable.

Alkanolamine etc. are mentioned as an alkali chemicals. As alkanolamine, monoethanolamine, diethanolamine, a triethanolamine, etc. are mentioned, for example, Alkanolamine may use together 1 type or 2 types or more.

The blending amount of these hydrotropes and alkali agents is preferably in the range of 0.1 to 10% by mass, and more preferably 1 to 5% by mass in the medical liquid detergent composition, respectively.

Moreover, the medical liquid detergent composition should just contain 0-1 mass% of C8-C22 fatty acids as an inhibitor. The fatty acid preferably has a carbon number in the range of 8 to 22, and a saturated fatty acid such as caprylic acid, capric acid, lauric acid, myristic acid, parmitic acid, stearic acid, or unsaturated fatty acid such as oleic acid, linoleic acid or linolenic acid. Any of Among them, parmitic acid is most preferred.

In addition, for the purpose of preventing recontamination, 0 to 2% by mass of recontamination inhibitors such as polyvinylpyrrolidone and carboxymethyl cellulose and for the purpose of improving cleaning power, and enzymes such as lipase, cellulase, amylase, and protease to 0 Dimethylsilicone, polyether-modified silicone, for the purpose of improving the feel of 0 to 3% by mass of calcium salts such as boric acid, borax, formic acid or its salts, calcium chloride and calcium sulfate, for the purpose of enzyme stabilization, 0-5 mass% of silicones, such as amino modified silicone, 0-1 mass% of fluorescent agents, such as a distyryl biphenyl type, for the purpose of whiteness improvement of a white medical | medical agent, 0.0001 to 0.001 mass% of pigments such as acid dyes for the purpose of coloring, and 0.0001 to 0.5 mass% of antioxidants such as dibutyl hydroxytoluene for the purpose of stabilization of fragrance. For antiseptic purposes, 0 to 0.05% by mass of antimicrobial agents such as Caison CG / ICP and 0 to 5% by mass of silicones such as higher fatty acids or polyether-modified silicones and amino-modified silicones for the purpose of defoaming. It can mix. Moreover, as a fragrance | flavor for fragrance | flavor, the fragrance composition etc. which contain a fragrance component, a solvent, and a stabilizer of Unexamined-Japanese-Patent No. 2002-146399 are mentioned, 0.01-1 mass in the medical liquid detergent composition of this invention. % Can be combined.

In addition, as the pH adjuster, inorganic acids such as sulfuric acid, sodium hydroxide, potassium hydroxide and inorganic bases can be blended. As the pH of the medical liquid detergent composition of the present invention, from the viewpoint of the onio salt cleaning power and the cleaning power retention after storage, 7.0 to 11.0 is preferable and 9.0-10.5 are more preferable. The compounding quantity of (E) component can be set so that pH may become this range.

The medical liquid detergent composition of this invention can be adjusted based on a conventional method suitably using water as a solvent.

The method of use is the usual method of use, that is, a method of putting into a water with laundry at the time of washing, a method of directly applying a medical liquid detergent composition to onion or sebum pollution, a method of dissolving clothes by dissolving the medical liquid detergent composition in water The method etc. are mentioned. Moreover, the method of leaving it to stand suitably after apply | coating a medical liquid detergent composition to a washing | cleaning, and carrying out normal washing | cleaning using the wash liquid containing an anionic surfactant after that is also preferable also.

Thus, in this invention, the medical liquid detergent composition which has favorable washing | cleaning power with respect to onion salt can be provided. In addition, the medical liquid detergent composition of the present invention exhibits high cleaning power against sebum contamination.

Example

Although an Example demonstrates this invention further in detail below, this invention is not limited to these Examples. In addition, unless otherwise indicated, "%" shows the "mass%."

(Examples 1 to 49, Comparative Examples 1 to 10)

The medical liquid detergent composition of the composition shown in the table was adjusted as follows. In addition, the unit of the compounding quantity in a table | surface is mass%, and the quantity of water was adjusted so that a total amount might be 100 mass%.

First, after stirring and melt | dissolving (A) component and polyethyleneglycol at 50 degrees C or less, it cooled to 40 degrees C or less. All subsequent processes were performed between room temperature and 40 degreeC. Then, (B) component and (E) component or diethanolamine were added and stirred. Thereafter, 90% of the mass of purified water (balance) was added, and the perfume was added thereto and stirred. Furthermore, after adding (C) component, (D) component, another arbitrary component, and a pigment, and stirring, pH was adjusted, the remaining purified water was added, and the medical liquid detergent composition was obtained.

pH adjustment was performed by adding a pH adjuster (sodium hydroxide or sulfuric acid) so that pH in 25 degreeC of the adjusted medical liquid detergent composition may be a value shown in a table | surface.

And it evaluated by the following method and evaluation criteria, and displayed the result in the table | surface.

<< explanation of the ingredients displayed in the table >>

(A) Component

A-1: C _n H _{2n +1} O (EO) ₁₅ H (n = 12/13 mixture (mass ratio 55/45)), (synthetic product obtained by the following synthesis method).

Synthesis method of A-1

224.4 g of a Sasol brand name Safol23 alcohol (branching rate ^{* 1} 50%) and 2.0 g of 30% Na0H aqueous solution were extract | collected in the pressure-resistant reaction container, and the inside of the container was substituted by nitrogen.

Next, dehydration was performed at a temperature of 100 占 폚 and a pressure of 2.0 kPa or lower for 30 minutes, and then the temperature was raised to 160 占 폚. 763.6 g of ethylene oxide (gas state) was gradually added to the alcohol in the liquid while adjusting the rate of addition so that the reaction temperature did not exceed 180 占 폚 while stirring the alcohol.

After completion | finish of addition of ethylene oxide, it aged at 30 degreeC and the pressure of 0.3 Mpa or less for 30 minutes, and unreacted ethylene oxide was distilled off for 10 minutes at the temperature of 180 degreeC and the pressure of 6.0 kPa or less.

Next, after cooling the temperature to 100 degrees C or less, 70% p-toluenesulfonic acid was added and neutralized so that the pH of the 1% aqueous solution of a reactant might be about 7, and A-1 was obtained.

^{* 1} Branching rate: A branching rate shows the ratio of the carbon number which comprises a branched chain with respect to all carbon number.

A-2: C _n H _{2n +1} CHC _m H _{2m +1} O (EO) ₉ H (m + n = 11 to 13),

Soaptanol 90 (average EO (ethylene oxide) 9 mol adduct of branched chain containing secondary alcohol) by the Japan Catalyst Corporation).

A-3: C _n H _{2n +1} O (EO) ₁₆ H (n = 12/14 mixture (mass ratio 71/29)), (synthetic product obtained by the following synthesis method).

Synthesis method of A-3

Using the P & G C _{12 ~ 14} alcohol 224.4g was synthesized as in the A-1.

A-4: C ₁₃ H ₂₇ O (EO) ₅ H (branching chain containing, diadol 13, branching ratio ^{* 1} 50%) (average EO 5 mol addition of branched chain containing higher alcohol of C13 by Mitsubishi Chemical Corporation) water).

A-5: C ₁₃ H ₂₇ (EO) ₇ H (C chain, branched), (manufactured by BASF, trade name: Lutcnzol TO7).

Component (B)

B-1: p-toluenesulfonic acid: Kyowa Fermentation Co., Ltd.

B-2: cumene sulfonic acid: Teiga Tox Corporation brand name "Teigatox 500"

B-3: m-xylene sulfonic acid: Mitsubishi Gas Chemical Co., Ltd. brand name "SXA-60"

(C) Component

C-1: lauryl amino propionic acid Na: Ippusha Yuji Co., Ltd.

C-2: lauric acid amide propyl betaine: Natural fine chemicals Co., Ltd. product name "Softazoline LPB"

C-3: n-dodecyldimethylamine oxide: Lion Arc Co., Ltd. product

C-4: Lauryl dimethyl betaine: Product name "Anhitol 4B" manufactured by Kao Corporation

C-5: Esogard C / 25 (trade name, product of Lion Arc Co., Ltd .; compound represented by general formula (II), except R ¹¹ ,: alkyl group derived from palm oil (C8 to 18), R ¹² : methyl group) , a + b = 15, X 1 - = Cl -)

C-6: Esamine SA2Y-103 (trade name, product of Lion Arc Co., Ltd .; compound represented by general formula (III), but R ¹³ : alkyl group derived from hardened tallow (C14 to 20), a + b = 50)

C-7: Esomer SAJ-103 (trade name, product of Lion Arc Co., Ltd .; compound represented by general formula (III), except R ¹³ : alkyl group derived from hardened tallow (C12 to 20), a + b = 10)

C-8: Bisol UP-10 (trade name, manufactured by Ipposha Oil Industry Co., Ltd .; compound represented by formula (II), except LR ¹¹ ,: alkyl group derived from Uji (C14 to 20), R ¹² : a benzyl group, a + b = 30, X 1 - = Cl -)

(D) Component

D-1: 1-hydroxyethane-1,1-diphosphonic acid: Brand name "BRIQUEST ADPA-A" made by ALBRITE & WILSON

(E) component

E-1: Monoethanolamine: Japan Catalyst Co., Ltd.

Random ingredient

Ethanolamine: Nippon Catalyst Co., Ltd.

Sodium Carbonate: Asa Glass Co., Ltd.

Sodium hydroxide: quasi-show chemical reagent

LAS-Na: Lion Corporation

Straight chain sodium alkylbenzenesulfonate (mixture of 10/12/14 carbon atoms of alkyl group)

Participate: Made by Japan Oil & Fat Co., Ltd.

Ethanol: 95vol% synthetic ethanol NED0

Polyethylene glycol: PEG # 1000 (mass average molecular weight 1000) manufactured by Nippon Oil Holding Co., Ltd.

Perfume composition: Perfume composition A to D according to Tables 11 to 18 described in Japanese Patent Application Laid-Open No. 2002-146399

Pigment A: Green 201, manufactured by Kishi Kasei Co., Ltd.

Pigment B: Yellow 201, manufactured by Kishi Kasei Co., Ltd.

Pigment C: Green No. 3, manufactured by Kishi Hwaseong Co., Ltd.

Dye D: Kirin Yellow WG-G CONC, manufactured by Joongang Synthetic Chemical Co., Ltd.

Stearyltrimethylammonium chloride: Lion Arc Co., Ltd. make

`` Storage Stability Assessment and Standards ''

100 ml of the medical liquid detergent composition was received and sealed in the glass bottle with a screw cap for 100 ml, and it preserve | saved for one month in 50 degreeC constant temperature room. The storage stability was visually compared to the medical liquid detergent composition after this storage and immediately after blending, and evaluated according to the following criteria.

A: There is no change from immediately after mixing.

B: Crystal | crystallization precipitates in a compound.

`` Onio salt cleaning power evaluation ''

5 g of horticultural black soil (manufactured by kyotochiya) was weighed, and charged into 500 g of tap water, and dispersed for about 5 minutes at 80 rpm using a homogenizer (KINEMATICA Switzerland), trade name Polytron Typc PT 10/35). In the obtained sludge dispersion, 15 sheets of cotton Meriya's knit cloth (dyeing material manufactured by Kokuto Co., Ltd., cotton knit unbleached) cut into 10 cm x 25 cm was immersed. The cloth was kneaded well by hand, and the sludge was uniformly included throughout the cloth. The cloth was taken out and lightly rolled with a roller. After naturally drying for 1 hour, the resultant was further dried for 1 hour in a constant temperature bath at 105 ° C.

Finally, the surface of the cloth was rubbed with a urethane sponge, and the excess sludge particles were dropped as a model sludge dye cloth for evaluation.

Each model onion salt cloth adjusted as mentioned above was divided into 5 sheets (2 * 2cm <2>), and it used for the experiment as this as an evaluation cloth.

The following method was applied to the washing | cleaning method. That is, 0.6 g of the medical liquid detergent composition is applied per 5 sheets of onion salts, and after leaving for 5 minutes, 5 pieces of onion salts are put into a Terg-O-Tometer (cleaning tester) as it is and 25 ° C tap water (hardness 3DH). 0.9 L was added and stirred for 10 minutes at 120 rpm, then transferred to a two tank washing machine (manufactured by Mitsubishi Electric Corporation, product number: CW-C30A1-H1), and dehydrated for 1 minute. Thereafter, rinsed with running water for 1 minute, dehydrated for 1 minute, and then dried by wind.

`` Evaluating Sebum Contamination ''

Ten sheets of sebum stains were prepared by rubbing the sebum stains of the face onto a 100-cotton plain weave (mi-stained cloth) cut at 10 cm angles.

As a washing method, 0.6 g of a medical liquid detergent composition was put into a Terg-O-Tometer, and after stirring for 30 seconds, 10 onio salts were put into a Terg-O-Tometer as it was and 15 degreeC tap water (hardness 3DH). 0.9 L was added and stirred at 120 rpm for 10 minutes, and it moved to a two tank type washing machine (made by Mitsubishi Electric Corporation, product number: CW-C30A1-H1), and dehydrated for 1 minute. Thereafter, rinsed with running water for 1 minute, dehydrated for 1 minute, and then dried by wind.

<< evaluation standard of washing power >>

The onion salt cleaning power and sebum stain cleaning power were measured by measuring a Z value of the original cloth before staining and the stained cloth before and after washing using a colorimetric color difference meter (trade name: SE2000, manufactured by Nippon Denshoku Co., Ltd.). Evaluated. The average value of 10 sheets was used for evaluation, respectively.

Washing rate (%) = (Z value after washing-Z value before washing) / (Z value before cloth-Z value before washing) * 100

Onion salt cleaning power was evaluated based on the following criteria.

A: Cleaning rate exceeds 25%

B: 20-25% of cleaning rate

C: cleaning rate less than 20%

Evaluation of sebum stain cleaning power was performed based on the following criteria.

A: The cleaning rate exceeds 60%

B: cleaning rate 40 to 60%

C: cleaning rate less than 40%

[Table 1]

[Table 2]

[Table 3]

[Table 4]

[Table 5]

TABLE 6

[Table 7]

[Table 8]

TABLE 9

[Table 10]

TABLE 11

As is clear from the results shown in Tables 1 to 11, it was confirmed that in the Examples according to the present invention, good cleaning power can be obtained for both onion and sebum salts. Moreover, when including (E) component further, it was confirmed that it is a composition excellent also in storage stability.

According to this invention, the medical liquid detergent composition which has favorable washing | cleaning power with respect to onion salt can be provided.

Claims (2)

(A) 2-50 mass% of polyoxyethylene alkyl ethers whose carbon number of a hydrophobic group is 10-20, and the average added mole number of ethylene oxide is 3-26; (B) the following general formula (I):

(Wherein X, Y and Z are each independently a hydrogen atom, C _n H _{2n +1} or (CH ₃ ) ₂ CH (wherein n is an integer of 1 to 3), and M is a hydrogen atom or an alkali metal atom) , Alkaline earth metal atoms, NH ^{4 +} or alkanolamines) Compound represented by; (C) a semipolar surfactant, an amphoteric surfactant, and the following general formula (II) or (III):

(Wherein, R ¹¹ ,, R ¹² are, each independently, an alkyl group or alkenyl group, a straight-chain hydroxyalkyl group, a tolyl group, a phenyl group, a benzyl lifter any one of a straight chain or branched chain having 1 to 20, R ¹³ Represents any of a linear or branched alkyl group or alkenyl group, a linear hydroxyalkyl group, a tolyl group, a phenyl group, or a benzyl group having 8 to 20 carbon atoms, EO represents an ethylene oxide group, and a and b each represent 0 or more. A + b represents 10 or more, and X ^- represents anion) At least one compound selected from the group consisting of compounds represented by And (D) 1-hydroxyethane-1,1-diphosphonic acid or its salt; Medical liquid detergent composition comprising a. The method of claim 1, Furthermore, (E) monoethanolamine is contained, The medical liquid detergent composition characterized by the above-mentioned.