KR101189552B1 - Hair growing promoter and manufacturing method for the same - Google Patents
Hair growing promoter and manufacturing method for the same Download PDFInfo
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Abstract
본 발명은 발모 촉진 내지 탈모 방지 효과를 가지며, 생국화 꽃잎 추출물, 생석류 알 추출물, 및 생지황 추출물을 유효성분으로 하는 발모촉진제 및 그 제조 방법에 관한 것이다.The present invention has a hair growth promoting effect to prevent hair loss, and relates to a hair growth promoting agent and a method for producing the same, including the chrysanthemum petal extract, green pomegranate egg extract, and fresh sulfur extract.
Description
본 발명은 생국화 꽃잎 추출물, 생석류 알 추출물, 및 생지황 추출물을 유효성분으로 하는 발모촉진제 및 그 제조 방법에 관한 것이다.The present invention relates to a hair growth promoter comprising a fresh chrysanthemum petal extract, a green pomegranate roe extract, and a live yellow sulfur extract as an active ingredient, and a method of manufacturing the same.
일반적으로 탈모증이라 함은 모발이 탈락하여 성기거나 또는 소실된 상태를 말하며, 독발증 또는 독두병이라고도 한다. 대표적인 탈모증으로 원형탈모증이 있다.In general, alopecia refers to a condition in which hair falls off due to genital or loss, and is also referred to as toxin or pox. Representative alopecia is alopecia areata.
모발은 대개 수명이 있으며, 끊임없이 빠지고 새로 나고 있으므로 1일에 70~80개 전후의 탈모는 생리적인 것이다. 비정상적으로 많이 빠지고 털이 성기게 되거나 부분적으로 많은 털이 빠져 대머리가 되는 것도 탈모증이라고 한다.Hair is usually lifespan, and it is constantly falling out and new, so hair loss around 70 to 80 per day is physiological. Alopecia is also known as alopecia, which causes a lot of hair loss and hair loss.
이러한 탈모증의 원인으로는 보통 유전성이 원인이 되는 선천성과 기타 환경의 영향을 받는 후천성으로 나뉘는 데, 오늘날 직접적인 원인으로는 과도한 스트레스나 두피근육의 긴장, 남성호르몬인 안드로겐의 과잉분비(상대적으로 여성호르몬의 분비 감소), 지루성 피부염 및 아토피성 체질, 물리적 자극 등이 있으며, 특히 과다한 지방의 섭취 및 공해 등이 주요 원인으로 알려져 있다.The causes of alopecia are usually divided into congenitals caused by heredity and acquired conditions influenced by other environments. Today, direct causes include excessive stress, tension in the scalp muscles, and excessive release of androgens, male hormones (relatively female hormones). Secretion of sediment), seborrheic dermatitis and atopic constitution, physical irritation, and the like, in particular, excessive fat intake and pollution are known as the main causes.
이와 같은 탈모증의 예방 및 치료제로서 각종 발모촉진제에 관한 기술이 제시된 바 있지만, 이들은 기대한 만큼의 발모촉진효과 및 탈모방지효과를 얻을 수 없는 등의 문제점이 있어 이에 대한 개선의 필요성이 대두되었다.
Although various techniques for promoting hair loss have been suggested as an agent for preventing and treating alopecia, they have problems such as hair growth promoting effect and hair loss preventing effect as expected, and thus there is a need for improvement.
본 발명은 상기와 같은 종래 기술의 문제점을 해결하기 위하여 안출된 것으로서, 생국화 꽃잎 추출물, 생석류 알 추출물, 및 생지황 추출물을 유효성분으로 하는 발모촉진제 및 그 제조 방법을 제공하고자 한다.
The present invention has been made to solve the problems of the prior art as described above, and to provide a hair growth promoting agent and a method for producing the same as an active ingredient, such as fresh chrysanthemum petal extract, green pomegranate egg extract, and fresh turmeric extract.
상기의 과제를 해결하기 위하여 본 발명은, 생국화 꽃잎, 생석류 알, 생지황 각각을 준비하는 단계 ; 상기 생국화 꽃잎, 상기 생석류 알, 상기 생지황 각각을 이들과 동일한 중량의 추출용매에 48시간 내지 96시간 침지한 후 여과하여 추출물을 얻는 단계 ; 상기 생국화 꽃잎 추출물 100중량부에 대하여 상기 생석류 알 추출물 100 중량부, 상기 생지황 추출물 100중량부, 글리세린 5중량부를 혼합하여 발모촉진제를 얻는 단계 ; 를 포함하여 이루어지는 것을 특징으로 한다.In order to solve the above problems, the present invention comprises the steps of preparing each chrysanthemum petals, stone pomegranate eggs, raw sulfur; Obtaining the extracts by immersing the fresh chrysanthemum petals, the green pomegranate eggs, and the fresh green sulfur each in an extraction solvent of the same weight for 48 hours to 96 hours, and then filtering them; Obtaining 100% by weight of the green pomegranate egg extract, 100 parts by weight of the live turmeric extract, and 5 parts by weight of glycerin based on 100 parts by weight of the fresh chrysanthemum petal extract to obtain a hair growth promoter; And a control unit.
상기에 있어서, 상기 추출용매는 정제수 30wt%와 알콜 70wt%의 혼합액일 수 있다.
In the above, the extraction solvent may be a mixture of purified water 30wt% and alcohol 70wt%.
본 발명의 다른 사상으로, 발모촉진제에 있어서, 생국화 꽃잎 추출물, 생석류 알 추출물, 및 생지황 추출물이 유효성분으로 함유되어 있는 것을 특징으로 한다.According to another aspect of the present invention, the hair growth promoting agent, characterized in that the chrysanthemum petal extract, the pomegranate egg extract, and the goji sulfur extract is contained as an active ingredient.
상기에 있어서, 상기 유효성분은 각각 동일 중량비로 함유되어 있는 것이 바람직하다.
In the above, it is preferable that the said active ingredient is contained in the same weight ratio, respectively.
본 발명은, 생국화 꽃잎 추출물, 생석류 알 추출물, 및 생지황 추출물을 유효성분으로 하는 발모촉진제 및 그 제조 방법에 관한 것으로서, 발모촉진은 물론 탈모 방지에 탁월한 효과가 있다.
The present invention relates to a hair growth promoter using a chrysanthemum petal extract, a green pomegranate egg extract, and a live turmeric extract as an active ingredient, and a method for producing the same, having an excellent effect on promoting hair growth and preventing hair loss.
도 1a 내지 도 3d는 본 발명의 실시예 1에 따른 육안 확인을 입증하기 위한 사진들.1A to 3D are photographs for demonstrating visual confirmation according to Example 1 of the present invention.
본 발모촉진제는, 생국화 꽃잎, 생석류 알, 생지황을 이용하여 제조된다.The hair growth promoting agent is produced using fresh chrysanthemum petals, green pomegranate eggs, and green poppies.
이들 유효성분 각각에 대하여 자세히 살펴본다.Let's take a closer look at each of these active ingredients.
국화 꽃잎의 효능에 관하여 본초강목에는 '오랫동안 복용하면 혈기에 좋고 몸을 가볍게 하며 쉬 늙지 않는다. 위장을 편안케 하고 오장을 도우며 사지를 고르게 한다. 그 밖에도 감기, 두통, 현기증에 유효하다.'고 기재되어 있으며, 국화는 그 성분 중에 눈과 간 기능 회복에 좋은 비타민 A, 비타민 B1, 콜린, 스타키드린, 아데닌 등이 함유되어 있는 것으로 알려져 있다.About the effect of chrysanthemum petals Herbal narcotics' long-term use is good for blood, light body and do not get old. Relax your stomach, help your intestines, and even your limbs. In addition, it is effective for colds, headaches, and dizziness. 'Chrysanthemum is known to contain vitamin A, vitamin B1, choline, stachydrin, and adenine, which are good for restoring eye and liver function.
국화 꽃잎 중 생국화 꽃잎은 주로 약재로서 이용되며, 건국화 꽃잎은 차 형태로 음용된다.
Among the chrysanthemum petals, the chrysanthemum petals are mainly used as medicinal herbs, and the chrysanthemum petals are consumed in the form of tea.
석류(엄밀히는 생석류 알)은, 1) 석류에 함유된 식물성 에스트로겐 성분은 여성의 생리 기능을 향상시키는 효용이 있으며, 2) 석류에는 비타민이 풍부하여 피부 미용에 뛰어난 효능을 가지며, 3) 많은 유기산, 미네랄, 칼슘 등이 있어 자연 면역력과 치유력을 향상시키며, 4) 비타민A 성분으로 인하여 시력 향상에 도움이 되는 것으로 알려져 있다.
Pomegranate (strictly pomegranate egg), 1) the phytoestrogens contained in the pomegranate has the effect of improving the physiological function of women, 2) pomegranate is rich in vitamins and excellent in skin care, 3) many Organic acids, minerals, calcium, etc. improve the natural immunity and healing, 4) vitamin A ingredients are known to help improve vision.
지황은 쌍떡잎식물로서 통화식물목 현삼과의 여러해살이 풀이다.Chihwang is a dicotyledonous plant that is a perennial herb with the Korean ginseng.
지황의 뿌리는 주로 한방 약재로 이용되며, 지황의 뿌리를 그대로 쓰는 것을 생지황이라 하며, 건조시켜 사용하는 것을 건지황이라 하며, 술을 넣고 쪄서 말린 것을 숙지황이라 한다.The root of the jihwang is mainly used as a herbal medicine, using the root of the jihwang is called raw jihwang, dried to use it is called guangjihwang, put alcohol and steamed dried sujeongjihwang.
생지황은 허약 체질, 토혈, 코피, 자궁 출혈, 생리불순, 변비에 효능이 있는 것으로 알려져 있다.
Saenghwanghwang is known to be effective in fragile constitution, hemorrhage, nosebleed, uterine bleeding, menstrual irregularities, constipation.
본 발명은 이상에서 설명한 3가지의 준비물을 각각 준비한 후, 이들로부터 추출물을 얻어낸 후, 이들 추출물을 혼합하여 발모촉진제를 얻게 된다.The present invention is to prepare each of the three preparations described above, and then obtain an extract from them, and then these extracts are mixed to obtain a hair growth promoter.
먼저 추출물을 얻는 과정을 설명한다.First, explain the process of obtaining the extract.
생국화 꽃잎 100g을, 정제수 30g 및 알콜 70g으로 이루어진 추출용매에 침지하여 상온 또는 냉장 상태로 48시간 내지 96시간 유지하여 유효성분을 추출하게 된다.100 g of fresh chrysanthemum petals are immersed in an extraction solvent consisting of 30 g of purified water and 70 g of alcohol to maintain an active ingredient for 48 to 96 hours at room temperature or in a refrigerated state.
이와 같이 추출용매에 침지된 생국화 꽃잎을 여과하여 고형 성분을 걸러내면 생국화 꽃잎 추출물을 얻을 수 있다. Thus, by filtering the raw chrysanthemum petals immersed in the extraction solvent to filter out the solid component can be obtained the chrysanthemum petal extract.
생석류 알 100g을, 정제수 30g 및 알콜 70g으로 이루어진 추출용매에 침지하여 상온 또는 냉장 상태로 48시간 내지 96시간 유지하여 유효성분을 추출하게 된다.100 g of fresh pomegranate eggs are immersed in an extraction solvent consisting of 30 g of purified water and 70 g of alcohol, and the active ingredient is extracted by maintaining the mixture for 48 to 96 hours at room temperature or in a refrigerated state.
이와 같이 추출용매에 침지된 생석류 알을 여과하여 고형 성분을 걸러내면 생석류 알 추출물을 얻을 수 있다. As described above, filtering the solid granules immersed in the extraction solvent to filter out the solid components may provide the extract of the granules of granules.
생지황 100g을, 정제수 30g 및 알콜 70g으로 이루어진 추출용매에 침지하여 상온 또는 냉장 상태로 48시간 내지 96시간 유지하여 유효성분을 추출하게 된다.100 g of raw sulfur is immersed in an extraction solvent consisting of 30 g of purified water and 70 g of alcohol to maintain an effective ingredient for 48 to 96 hours at room temperature or in a refrigerated state.
이와 같이 추출용매에 침지된 생지황을 여과하여 고형 성분을 걸러내면 생지황 추출물을 얻을 수 있다.
In this way, by filtering the solid component by filtering the raw sulfur, which is immersed in the extraction solvent, the raw sulfur can be obtained extract.
상기와 같이 추출물을 얻을 때, 각각의 유효성분들의 효율적인 추출을 위하여, 재료들을 추출용매에 침지한 상태에서 혹은 추출용매에 침지하기 전에 추출물을 잘게 찧는 것이 바람직하다.
When obtaining the extract as described above, in order to efficiently extract the respective effective ingredients, it is preferable to finely chop the extract in the state of immersing the material in the extraction solvent or before immersing in the extraction solvent.
상기와 같이 생국화 꽃잎 추출물, 생석류 알 추출물, 생지황 추출물을 얻게 되면, 이들을 동일 중량비로 혼합하되, 생국화 꽃잎 추출물 100중량부에 대하여 글리세린 5중량부를 첨가하여 본 발명에 의한 외용액제를 제조한다.When obtaining the chrysanthemum petal extract, green pomegranate egg extract, raw chrysanthemum extract as described above, they are mixed in the same weight ratio, to prepare the external solution according to the present invention by adding 5 parts by weight of glycerin to 100 parts by weight of fresh chrysanthemum petal extract. .
글리세린은 피부 흡수력을 높이기 위한 보조제이다.
Glycerin is a supplement to increase skin absorption.
상기와 같이 제조된 본 발명에 따른 발모촉진제는 외용으로 사용되는 액제형태로서, 그 사용에 있어 매우 편리한 장점이 있으며, 또한 약제 투약시 1일 1~2회 1~3cc 정도씩 피부에 투약하는 것이 바람직하다.Hair growth promoter according to the present invention prepared as described above is a liquid form used for external use, there is a very convenient advantage in its use, and also to administer to the skin once or twice a day 1 ~ 2cc when administering the drug desirable.
또한 본 발명에 따른 발모촉진제의 투약과 함께 건국화 꽃잎을 이용한 차를 함께 음용하면 더욱 본 발모촉진제의 효능을 증대시킬 수 있다.
In addition, the tea using the chrysanthemum petal together with the administration of the hair growth promoter according to the present invention can further increase the efficacy of the hair growth promoter.
실시예 1.Example 1.
생국화 꽃잎 100g을 정제수 30g 및 알콜 70g인 추출용매에 3일간 침지한 후 여과하여 생국화 꽃잎 추출물을 얻고, 생석류 알 100g을 정제수 30g 및 알콜 70g인 추출용매에 3일간 침지한 후 여과하여 생석류 알 추출물을 얻고, 생지황 100g을 정제수 30g 및 알콜 70g인 추출용매에 3일간 침지한 후 여과하여 생지황 추출물을 얻은 후, 이들 추출물을 동일 중량비로 혼합하되 생국화 꽃잎 추출물 100 중량부에 대하여 글리세린 5중량부를 첨가하여 발모촉진제를 제조하였다.100 g of fresh chrysanthemum petals were immersed in an extraction solvent of 30 g of purified water and 70 g of alcohol for 3 days, followed by filtration to obtain a fresh chrysanthemum petal extract, and 100 g of fresh pomegranate eggs were immersed in 3 g of purified water of 30 g of purified water and 70 g of alcohol for 3 days and then filtered. Obtain pomegranate egg extract, immerse 100g of raw sulfur in 100g of purified water 30g and 70g of alcohol, and soak for 3 days, and then filter it to obtain raw sulfuric acid extract, and then mix these extracts in the same weight ratio, but
이 발모촉진제를 탈모 환자 5명의 탈모 부위에 1일 2회 각각 3cc씩 6개월간 적용하였다.This hair growth promoter was applied to hair loss sites of five hair loss patients twice a day for 3 months each for 3 months.
그 결과 탈모 환자 5명 모두에게서 새로운 모근이 발생하는 것을 육안으로확인하였다.
도 1a 내지 도 1d는 70대 남성의 실시예 1에 따른 경과 사진들을 순차적으로 촬영한 것이며, 도 2a 내지 도 2d는 40대 남성의 실시예 1에 따른 경과 사진들을 순차적으로 촬영한 것이며, 도 3a 내지 도 3d는 30대 여성의 실시예 1에 따른 경과 사진들을 순차적으로 촬영한 것이다.
As a result, it was visually confirmed that all 5 hair loss patients developed new hair roots.
1A to 1D are photographs of progressive images according to Example 1 of a man in his 70s, and FIGS. 2A to 2D are photographs of progressive images according to Example 1 of a man in his 40s, and FIG. 3A 3D is a sequential photograph of progressive pictures according to Example 1 of a woman in her 30s.
실시예 2.Example 2.
실시예 1과 같이 제조된 발모촉진제를 실시예 1과 같이 탈모 환자 5명의 탈모 부위에 1일 2회 각각 3cc씩 6개월간 적용함과 동시에, 탈모 환자들이 매일 건국화 잎 2g에 의하여 만들어진 국화차를 함께 음용하도록 하였다.The hair growth promoter prepared in Example 1 was applied to the hair loss site of 5 hair loss patients as per Example 1 for 3 months, 3cc each for 6 months, and the hair loss patients used chrysanthemum tea made by 2g of dried chrysanthemum daily. Drinked together.
그 결과 탈모 환자 5명 모두에게서 새로운 모근이 발생하는 것이 육안 확인되었을 뿐만 아니라, 투약일로부터 4개월만에 모근 발생을 확인할 수 있어 국화차가 본 발모촉진제의 효능을 증대시킴을 확인할 수 있었다.
As a result, not only the new hair roots were visually confirmed in all 5 hair loss patients, but also the hair roots could be confirmed only 4 months after the administration date, indicating that chrysanthemum tea increased the efficacy of the hair growth promoting agent.
비교예 1. Comparative Example 1
생국화 꽃잎 100g을 정제수 30g 및 알콜 70g인 추출용매에 3일간 침지한 후 여과하여 생국화 꽃잎 추출물을 얻고, 생석류 알 100g을 정제수 30g 및 알콜 70g인 추출용매에 3일간 침지한 후 여과하여 생석류 알 추출물을 얻은 후, 이들 추출물을 동일 중량비로 혼합하되 생국화 꽃잎 추출물 100 중량부에 대하여 글리세린 5중량부를 첨가하여 발모촉진제를 제조한 후, 실시예 1과 동일한 방법으로 탈모 환자 5명에게 투약하였다.100 g of fresh chrysanthemum petals were immersed in an extraction solvent of 30 g of purified water and 70 g of alcohol for 3 days, followed by filtration to obtain a fresh chrysanthemum petal extract, and 100 g of fresh pomegranate eggs were immersed in 3 g of purified water of 30 g of purified water and 70 g of alcohol for 3 days and then filtered. After obtaining pomegranate egg extract, these extracts were mixed in the same weight ratio, but 5 parts by weight of glycerin was added to 100 parts by weight of the chrysanthemum petal extract to prepare a hair growth accelerator, and then administered to 5 hair loss patients in the same manner as in Example 1. It was.
실험 결과 5명 모두 모근 발생이 확인되지 않아 발모 촉진 내지 탈모 방지에 효능이 없음을 확인할 수 있었다.
As a result of the experiment, all five hair roots were not confirmed, and thus, there was no efficacy in promoting hair growth or preventing hair loss.
비교예 2.Comparative Example 2
생국화 꽃잎 100g을 정제수 30g 및 알콜 70g인 추출용매에 3일간 침지한 후 여과하여 생국화 꽃잎 추출물을 얻고, 생지황 100g을 정제수 30g 및 알콜 70g인 추출용매에 3일간 침지한 후 여과하여 생지황 추출물을 얻은 후, 이들 추출물을 동일 중량비로 혼합하되 생국화 꽃잎 추출물 100 중량부에 대하여 글리세린 5중량부를 첨가하여 발모촉진제를 제조한 후, 실시예 1과 동일한 방법으로 탈모 환자 5명에게 투약하였다.100 g of fresh chrysanthemum petals were immersed in an extract solvent of 30 g of purified water and 70 g of alcohol for 3 days, followed by filtration to obtain a fresh chrysanthemum petal extract, and 100 g of fresh chrysanthemum was immersed in 30 g of purified water and 70 g of alcohol for 3 days, followed by filtration. After the preparation, these extracts were mixed in the same weight ratio, but 5 parts by weight of glycerin was added to 100 parts by weight of the fresh chrysanthemum petal extract to prepare a hair growth accelerator, and then administered to 5 hair loss patients in the same manner as in Example 1.
실험 결과 5명 모두 모근 발생이 확인되지 않아 발모 촉진 내지 탈모 방지에 효능이 없음을 확인할 수 있었다.
As a result of the experiment, all five hair roots were not confirmed, and thus, there was no efficacy in promoting hair growth or preventing hair loss.
아울러 실시예 1에 의하여 제조된 발모촉진제는 각종 피부병에 효과가 있는 것으로 확인되었다. 예컨데, 무좀, 아토피성 피부염, 모기 등의 벌레 물린 부위에 실시예 1에 의하여 제조된 발모촉진제를 투약하면 약효가 있는 것으로 확인되었다.
In addition, the hair growth accelerator prepared in Example 1 was confirmed to be effective in various skin diseases. For example, when the hair growth promoter prepared in Example 1 is administered to insect bites such as athlete's foot, atopic dermatitis, and mosquitoes, it is confirmed that the drug has an effect.
본 발명의 범위는 상기 상세한 설명보다는 후술하는 특허청구범위에 의하여 나타내어지며, 특허청구범위의 의미 및 범위 그리고 그 균등 개념으로부터 도출되는 모든 변경 또는 변형된 형태가 본 발명의 범위에 포함되는 것으로 해석되어야 한다.
The scope of the present invention is defined by the appended claims rather than the detailed description and all changes or modifications derived from the meaning and scope of the claims and their equivalents are to be construed as being included within the scope of the present invention do.
본 발명은 발모 촉진을 위한 외용액제로서 사용될 수 있다.The present invention can be used as an external solution for promoting hair growth.
Claims (4)
상기 생국화 꽃잎, 상기 생석류 알, 상기 생지황 각각을 이들과 동일한 중량의 추출용매에 48시간 내지 96시간 침지한 후 여과하여 추출물을 얻는 단계 ;
상기 생국화 꽃잎 추출물 100중량부에 대하여 상기 생석류 알 추출물 100 중량부, 상기 생지황 추출물 100중량부, 글리세린 5중량부를 혼합하여 발모촉진제를 얻는 단계 ;
를 포함하여 이루어지는 것을 특징으로 하는 발모촉진제의 제조 방법.
Preparing each of the chrysanthemum petals, the pomegranate eggs, and the lively sulfur;
Obtaining the extracts by immersing the fresh chrysanthemum petals, the green pomegranate eggs, and the fresh green sulfur each in an extraction solvent of the same weight for 48 hours to 96 hours, and then filtering them;
Obtaining 100% by weight of the green pomegranate egg extract, 100 parts by weight of the live turmeric extract, and 5 parts by weight of glycerin based on 100 parts by weight of the fresh chrysanthemum petal extract to obtain a hair growth promoter;
Method for producing a hair growth promoting agent comprising a.
상기 추출용매는 정제수 30wt%와 알콜 70wt%의 혼합액인 것을 특징으로 하는 발모촉진제의 제조 방법.
The method of claim 1,
The extracting solvent is a method for producing a hair growth promoter, characterized in that the mixture of purified water 30wt% and alcohol 70wt%.
Raw chrysanthemum petal extract, pomegranate egg extract, and gojihwang extract is contained as an active ingredient, the active ingredient, characterized in that each of the active ingredient is contained in the same weight ratio.
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| KR100451885B1 (en) * | 2002-02-15 | 2004-10-08 | 우민무역주식회사 | Extracts of pomegranate for stoping the hair from falling out and composition of cosmetics containing the extracts of pomegranate |
| KR100554948B1 (en) * | 2005-10-18 | 2006-03-03 | 주식회사 케이엠에스아이 | Herbal composition having hair loss prevention and hair growth promoting effect |
| KR100776346B1 (en) | 2006-06-14 | 2007-11-16 | 주식회사 바이오랜드 | Composition with anti-dandruff, anti-inflammatory activity, containing nasturtium, succinate, sewage, and half-mixed herbal extract |
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| KR100451885B1 (en) * | 2002-02-15 | 2004-10-08 | 우민무역주식회사 | Extracts of pomegranate for stoping the hair from falling out and composition of cosmetics containing the extracts of pomegranate |
| KR100554948B1 (en) * | 2005-10-18 | 2006-03-03 | 주식회사 케이엠에스아이 | Herbal composition having hair loss prevention and hair growth promoting effect |
| KR100776346B1 (en) | 2006-06-14 | 2007-11-16 | 주식회사 바이오랜드 | Composition with anti-dandruff, anti-inflammatory activity, containing nasturtium, succinate, sewage, and half-mixed herbal extract |
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