KR101182914B1 - Wound protection means and method producting the same - Google Patents

Abstract

A wound protection member and a method of manufacturing the same are disclosed. Wound protection member according to an embodiment of the present invention covers a wound site to protect the wound site; And a drug layer for treating the wound site mounted on one surface of the cover layer, wherein the cover layer has a silk or wool material.

Description

Wound protection member and its manufacturing method {WOUND PROTECTION MEANS AND METHOD PRODUCTING THE SAME}

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a wound protection member and a method of manufacturing the same, and more particularly, to a wound protection member employing a silk or wool material and a method of manufacturing the same.

Wound protecting members are often used to protect the wound site from external contact by covering the wound site when a wound occurs in the human body. Representative of such wound protection members include medical dressings, hemostatic agents, medical bandages, band-aids, surgical gauze and the like.

These wound protection members serve to cover the wound area and thus inevitably include a contact portion with the wound site. The higher the human fitness of such contacts, the less likely that the wound protection members will fulfill their inherent role in protecting the wound, as well as inducing undesired side effects.

Many wound protection members on the market employ artificial materials such as polyurethane as the material for contacting the wound site. These artificial materials generally have a relatively low human suitability compared to natural materials.

Therefore, development of wound protection members having improved human suitability compared to the prior art is required.

SUMMARY OF THE INVENTION An object of the present invention is to provide a wound protection member and a method of manufacturing the same having improved human suitability as compared with the prior art.

In order to achieve the above object, the present invention, the cover layer to cover the wound site to protect the wound site; And a drug layer for treating the wound site mounted on one surface of the cover layer, wherein the cover layer has a silk or wool material.

Here, the cover layer may have a material in which silk and wool are mixed.

A plurality of pores may be formed on the one surface of the cover layer.

The drug layer may include one or more of calcium alginate, growth factor and hyaluronic acid.

It may further include an adhesive layer attached to the other surface of the cover layer to fix the cover layer to the wound site.

A protective layer may be attached to the outer surface of the drug layer to prevent the outer detachment of the drug layer.

In order to achieve the above object, the present invention, the cover layer manufacturing step of using a silk or wool material to cover the wound area to produce a cover layer to protect the wound area; And a drug layer mounting step of mounting a drug for treating the wound site on one surface of the cover layer.

The method of manufacturing the wound protection member may further include a pore forming step of forming a plurality of pores on the one surface of the cover layer before the drug layer mounting step.

The manufacturing method of the wound protection member may further include a protective layer attaching step of attaching a protective layer for preventing the outer detachment of the drug layer on the outer surface of the drug layer.

The method for manufacturing the wound protection member may further include an adhesive layer attaching step of attaching an adhesive layer for fixing the cover layer to the wound site on the other surface of the cover layer.

Here, the cover layer may have a material in which silk and wool are mixed.

1 is a perspective view of a wound protection member according to an embodiment of the present invention.
FIG. 2 is an enlarged cross-sectional view of the wound protection member of FIG. 1 taken along line II-II. FIG.
3 is a flowchart illustrating a method of manufacturing a wound protection member according to an embodiment of the present invention.

Hereinafter, a wound protection member and a method of manufacturing the same according to embodiments of the present invention will be described with reference to the accompanying drawings.

1 is a perspective view of a wound protection member according to an embodiment of the present invention, Figure 2 is an enlarged cross-sectional view taken along the line II-II of the wound protection member of FIG.

1 and 2, the wound protection member 1 according to an embodiment of the present invention includes a cover layer 10, a drug layer 20, an adhesive layer 30, and a protective layer 40.

The cover layer 10 covers the wound site of the human body to protect the wound site from external contact. When the wound is exposed to the outside, the wound may be exacerbated or the spontaneous healing may be slowed by the external contact, and the patient may feel pain by stimulating the nerve exposed by the external contact. To prevent these problems, the cover layer 10 separates and protects the wound from the outside so that the wound does not directly contact the outside.

Various materials may be applied to the cover layer 10 including natural materials and artificial materials. The cover layer 10 preferably has a certain level or more of elasticity to cushion external contact, and the cover layer 10 is preferably excellent in human compatibility due to the property of being in direct contact with the human body. Thus, the cover layer 10 of the present embodiment is manufactured from silk-wool mixed fibers composed of silk and wool in consideration of cushioning and human fitness. Silk and wool is a material excellent in human compatibility, and therefore, the cover layer 10 made of silk-wool mixed fibers may naturally have excellent human compatibility.

In this embodiment, the material of the cover layer 10 is mixed with silk and wool fibers, but in alternative embodiments, the material of the cover layer 10 may be a silk sole fiber or a wool sole fiber. .

The upper surface 12 of the cover layer 10 has a number of pores 14 having a groove shape recessed inwardly. These pores may be formed by, for example, immersing the silk-wool mixed fiber, which is the material of the cover layer 10, in an alkaline solution. As the alkaline solution, for example, a solution in which water and sodium hydroxide (NaOH) are mixed may be used. By increasing the surface area of the upper surface 12 of the cover layer 10 by these pores 14, the drug retention capacity of the cover layer 10 can be improved, thereby the drug to be mounted on the cover layer 10 The layer 20 may penetrate more slowly into the wound (ie, improved sustained release)

In this embodiment, only the pores are formed on the upper surface 12 of the cover layer 10, but in other alternative embodiments the pores may be formed entirely throughout the surfaces and the interior of the cover layer 10. have. According to these alternative embodiments, the hygroscopicity, breathability and drug sustained release of the cover layer 10 may be further improved.

The drug layer 20 is mounted on the upper surface 12 of the cover layer 10 to assist in the healing action of the wound site. The drug layer 20 may be applied with various kinds of things according to the type of wound, the purpose of treatment, and the like. The drug layer 20 of the present embodiment includes at least one of calcium alginate, growth factor, and hyaluronic acid. The growth factor may be epidermal growth factor (EGF) or fibroblast growth factor (bFGF). By the drug layer 20, hemostasis or healing of the wound site may be promoted more.

The adhesive layer 30 is for fixing the cover layer 10 to the wound site. Thus, the adhesive layer 30 is attached to the lower surface 16 of the cover layer 10, the adhesive material is applied to the upper surface 32 of the adhesive layer 30. In addition, the adhesive layer 30 has a larger surface area than the cover layer 10 and the cover layer 10 is disposed at the center of the adhesive layer 30. By providing the adhesive layer 30, the user can conveniently fix the wound protection member 1 to the wound site without any other adhesive means such as an adhesive tape. In alternative alternative embodiments such an adhesive layer 30 may not be provided, in which case the cover layer 10 is secured to the wound by other adhesive means such as adhesive tape.

The protective layer 40 is for preventing the drug layer 20 mounted on the cover layer 10 from unintentionally leaving the outside before use or during preparation for use. When using the wound protection member 1, the protective layer 40 is removed from the drug layer 20 by the user.

As shown in Fig. 1, the wound protection member 1 of this embodiment has a rectangular shape whose transverse length is slightly longer than the longitudinal length. However, in alternative embodiments, the wound protection member may have a rollable shape, such as a bandage, because the transverse length is formed several times to several tens of times longer than the longitudinal length. In such embodiments, the wound protection member is suitable to be cut to an appropriate size according to the size of the wound and the like, and it may be more preferable to use other adhesive means such as an adhesive tape in use rather than having an adhesive layer on its own. .

An embodiment of the wound protection member 1 manufacturing method described above with reference to FIG. 3 will be described. 3 is a flowchart illustrating a method of manufacturing a wound protection member according to an embodiment of the present invention.

First, the cover layer 10 is manufactured in step S10. The cover layer 10 is made using silk-wool mixed fibers. Such silk-wool mixed fibers may be used in the form of a woven fabric or may be used in the form of a non-woven fabric. Silk-wool mixed fibers in the form of a non-woven fabric can be produced by a papermaking method (immersion method) or a thermal fusion method, and the like, since the fiber manufacturing method is well known, details thereof will be omitted.

Next, pre-processing for forming a plurality of pores 14 on the surface of the cover layer 10 in step S20. These pores 14 may be formed by immersing the silk-wool mixed fiber which is the raw material of the cover layer 10 in an alkaline solution. In this case, the alkaline solution may be, for example, a mixed solution of water and sodium hydroxide. Serisin and fibroin, which are the major components of silk, and keratin, which is the major component of wool, are partially removed by alkaline solution, thereby forming a plurality of pores 14 on the surface of the cover layer 10. Can be. As described above, the drug retention of the cover layer 10 may be improved by the plurality of pores 14 formed on the surface of the cover layer 10, thereby improving drug sustained release of the cover layer 10.

Next, in step S30 the drug is mounted on the upper surface 12 of the cover layer 10 to form a drug layer 20. Various drugs can be applied depending on the type of wound, the purpose of treatment, and the like. In this embodiment, one or more of calcium alginate, growth factor, and hyaluronic acid having hemostatic and wound healing functions are applied. Herein, epidermal growth factor (EGF) and fibroblast growth factor (bFGF) may be used as growth factors.

Next, the protective layer 40 is attached to the outer surface of the drug layer 20 in step S40. The protective layer 40 is to prevent unintentional external detachment of the drug layer 20 when the wound protection member 1 is not used or prepared for use, and the protective layer 40 when the wound protection member 1 is used. ) May be removed in advance by the user. In another alternative embodiment, the protective layer 40 may not be provided unless the drug layer 20 has a relatively high detachability.

Next, in step S50, the adhesive layer 30 is attached to the lower surface 16 of the cover layer 10. An adhesive material is applied on one surface 32 of the adhesive layer 30 attached to the cover layer 10, and the adhesive layer 30 is attachable to the wound site by the adhesive material. Thus, the wound protection member 1 may be easily fixed to the wound site without the aid of other means such as an adhesive tape. In alternative alternative embodiments, it may be possible to secure the wound protection member 1 to the wound site via other means, such as adhesive tape, without the adhesive layer 30.

In the wound protection member 1 and the manufacturing method according to the embodiments of the present invention described above, silk-wool mixed fibers are used as the material of the cover layer 10. However, in alternative embodiments of the present invention, it is also possible to manufacture the cover layer 10 from silk sole fibers or wool sole fibers.

Here, the advantages that can be obtained when silk or wool is adopted as the material of the cover layer 10 will be described in more detail.

First, silk will be described. Silk is a fiber obtained from silkworm cocoons. It is not only high in aesthetics due to elegant gloss, vivid color, high draping ability, but also excellent in contact, warmth, comfort, and light weight, and it is almost among many fibers. It is a material with perfection property.

Silk is composed mainly of fibroin protein and sericin protein, and also contains a small amount of brain, lipid and inorganic salts. Fibroin and sericin, the main components of silk, are biopolymers that are formed in all animals and are similar to human cellular components. Naturally, silk is highly compatible with human body. In particular, sericin, which is a major component of silk, has not only excellent water retention and moisturizing properties, but also has recently been found to have antioxidant activity and tyrosinase activity inhibition. In addition, serine is reported to greatly promote cell proliferation.

As a result, silk has excellent body compatibility, skin compatibility, biodegradability, and hemostasis and wound healing functions based on the characteristics of its main components, fibroin and sericin. Accordingly, silk has great suitability as a material of the cover layer 10 of the wound protection member 1.

Next, wool will be described. Wool is the most elastic material among the natural fibers and has excellent heat retention and hygroscopicity, and keratin is the main ingredient. In recent years, wool keratin has excellent antithrombogenic properties, does not show antigenicity in vivo, and its degradation products do not show toxicity. Wool keline has a high affinity for biological tissue because its structure is a peptide bond like collagen fiber and elastin, which is a component of skin. For reference, keratin is divided into euukeratin and pseudokeratin, where eukeratin is contained in wool or feathers, while pseudokeratin is included in human skin and proteolytic enzymes. Digestible by In light of this, it is possible to denature wool keratin and make it into a digestible form by proteolytic enzymes.

As a result, wool not only has good heat retention, hygroscopicity and buffering properties, but also has excellent human fitness, skin compatibility and biodegradability due to the characteristics of keratin, its main ingredient. Thereby, the wool has great suitability as a material of the cover layer 10 of the wound protection member 1 like silk.

As described above, the silk and wool as the material of the cover layer 10 in the present embodiment is not only excellent in human fitness, skin compatibility, biodegradation suitability, but also moisturizing, hygroscopic, buffering, hemostatic or It contains wound healing. Accordingly, the wound protection member 1 having such a cover layer 10 has an improved therapeutic effect compared to other conventional ones, but is less likely to cause side effects due to human incompatibility.

The wound protection member according to the embodiments described above includes, for example, a cover layer (cover member) for covering a wound site, such as a medical dressing, a medical band, and the like, and a drug is mounted on one surface thereof. It will be apparent to those skilled in the art that the present invention can be applied to various types of medical articles.

One ; Wound Protector 10: Cover Layer
14: pore 20: drug layer
30: adhesive layer 40: protective layer

Claims (11)

A cover layer covering the wound to protect the wound; And
And a drug layer for treating the wound site mounted on one surface of the cover layer.
The cover layer has a silk or wool material, a wound protection member, characterized in that a plurality of pores are formed on at least one side surface of the cover layer. The method of claim 1,
The cover layer is a wound protection member, characterized in that it has a material mixed with silk and wool. delete The method of claim 1,
The drug layer wound protection member, characterized in that it comprises at least one of calcium alginate, growth factor and hyaluronic acid. The method of claim 1,
And an adhesive layer attached to the other surface of the cover layer to fix the cover layer to the wound site. The method of claim 1,
And a protective layer adhered to an outer surface of the drug layer to prevent external detachment of the drug layer. A cover layer manufacturing step of using a silk or wool material to cover the wound to produce a cover layer to protect the wound; And
The drug layer mounting step of mounting a drug for the treatment of the wound site on the surface of one side of the cover layer; manufacturing method of a wound protection member comprising a. The method of claim 7, wherein
And a pore forming step of forming a plurality of pores on at least one surface of the cover layer before the drug layer mounting step. The method of claim 7, wherein
And a protective layer attaching step of attaching a protective layer for preventing external detachment of the drug layer on an outer surface of the drug layer. The method of claim 7, wherein
An adhesive layer attaching step of attaching an adhesive layer for fixing the cover layer to the wound site on the other side surface of the cover layer. The method of claim 7, wherein
The cover layer is a method of manufacturing a wound protection member, characterized in that the material is mixed with silk and wool.

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