CN208511564U - A kind of composite collagen wound dressing - Google Patents
A kind of composite collagen wound dressing Download PDFInfo
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- CN208511564U CN208511564U CN201721488965.5U CN201721488965U CN208511564U CN 208511564 U CN208511564 U CN 208511564U CN 201721488965 U CN201721488965 U CN 201721488965U CN 208511564 U CN208511564 U CN 208511564U
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- wound dressing
- protein sponge
- release paper
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Abstract
A kind of composite collagen wound dressing, is made of fixing layer, collagen protein sponge and release paper, and wherein fixing layer is made of protective layer, adhesive layer, or is made of protective layer, adhesive layer and separation layer.For preventing wound infection, fixed dressing, the healing of guidance wound tissue.The composite collagen wound dressing has the various sizes and shape that can be freely combined, suitable for different wounds or different human body position.Collagen protein sponge is in packaging, packaging, sterilizing can be combined with fixing layer and release paper, release paper use is directly torn when use, collagen protein sponge is towards wound, it sterilizes after can also individually being packed with fixing layer and release paper, recombinant uses together when use, first applies collagen protein sponge layer, reuses fixing layer and fix.
Description
Technical field
The utility model belongs to medical material tech field, and novel collagen wound dressing can be freely combined by being related to one kind,
More particularly to a kind of protection wound, the composite construction for the wound dressing for absorbing drainage tissue raffinate and guiding tissue growth.
Background technique
Skin surface is easily infected by extensive wound or burn, wound, and infection causes have a fever inflammation or suppuration, sternly
The life of people is threatened when weight；It needs to create shielding system, wound is protected not to be infected by bacterial or do not make when contacting with the external world
At secondary injury, and under dampness wound healing than healing in the dry state fastly；[1 Qin Yi people's new medical applies
Material: wound type and its requirement (I) [J] textile journal to dressing, 2003,24 (5): 113-115..2003.05.046.],
This discovery accelerates the development and use of wound dressing, and effect of the medical dressing in wound healing process is protection wound, control
It makes infection, be provided with the moist environment conducive to wound healing.
CN201310123232.1 discloses a kind of porous sponge wound dressing of collagen-based with from anti-inflammatory properties, application
In the reparation of the multiple types skin trauma such as burn, mechanical damage, collagen protein sponge does not have caking property, although to Wound during Dressing Change
Shi Buhui destroys the tissue of wound, but also needs to be fixed using gauze, and such functional medical collagen sea
Silk floss cannot flexibly carry out drug loading in order to avoid the conflict of drug.
Dressing is fixed using gauze, it may appear that dressing dislocation, phenomena such as falling off, to solve the problems, such as this usually to adopt
Dressing is fixed with medical proof fabric, or directly uses medical application；And in clinical application, there are some patientss to medical adhesive
Cloth, adhesive tape, application allergy cause patient skin and adhesive plaster or application contact site itch, redness, blister occur and even fester
Allergic symptom causes the condition of the injury to deteriorate；Regenerated cellulose/collagen composite wound dressing outer layer regenerated cellulose has good
Good antibiotic property, moisture retention, collagen layer guide tissue regeneration, material it is in the form of a single, can not flexibly carry out drug
Load, needs separately to shear that [2 Lu Jin are graceful, Cheng Yongmei, and the such as Zhao Peng regeneration is fine to the wound of different wound or different parts
Dimension element/collagen composite wound dressing preparation and its performance evaluation * [J] functional material, 2014, (14): 14150-
14155.DOI:10.3969/j.issn.1001-9731]。
Utility model content
To solve the above problems, the utility model provides a kind of collagen wound dressing that can be freely combined.This is practical new
Technical solution used by type is:
A kind of novel collagen wound dressing, by fixing layer, release paper and the collagen protein sponge group to sterilize after individually packing
At, have different size and shapes, can be freely combined according to different needs.
The fixing layer is made of non-woven fabrics protective layer, hot melt adhesive adhesive layer, or by non-woven fabrics protective layer, heat
Melten gel adhesive layer and cotton separation layer composition.
It is that one of ox, horse, pig, sheep, fish extract skin or tendon passes through that the collagen protein sponge, which is by animal,
Digest, saltout, dialysing and etc. I type that is prepared or I type and III collagen type mixed solution, by being lyophilized, being crosslinked
And etc., using hot dehydrogenation crosslinking method or the obtained collagen protein sponge of Chemical Crosslinking Methods, collagen protein sponge
With a thickness of 0.5~5mm, porosity is 50~99.9%.
The collagen protein sponge first can carry out drug loading, then stick wound when in use, then with fixing layer
It is used in combination, is suitable for the wound of different physical feelings and size.The fixing layer needs release paper to cover before being not used
It covers on the adhesive layer of fixing layer, to protect the viscosity of adhesive layer.
The collagen protein sponge can combine packaging, sterilizing with fixing layer and release paper, make in packaging
Used time directly tears release paper use, and collagen protein sponge is towards wound, after can also individually packing with fixing layer and release paper
Sterilizing, recombinant uses together when use, first applies collagen protein sponge layer and sticks wound and applies the fixed protection of fixing layer again.
Moreover, protective layer protects wound not to be infected by bacterial or cause secondary injury, while also there is good moisturizing
Property and gas permeability；Adhesive layer has good caking property, and can fix collagen protein sponge prevents the loosening of collagen protein sponge.
Moreover, the protective layer has different shape specifications, there are H-shaped, rectangle, circle, spill, adhesive bandage shape etc.；
The shape of the collagen protein sponge layer has rectangle, circle, adhesive bandage etc., and thickness is in 0.01~1mm.
The raw material of protective layer are in addition to non-woven fabrics, and there are also medical PU films.
Moreover, the non-woven fabrics is by plant fiber, collagen fabric, polypropylene fibre, polyurethane fiber, carbon fiber
Or their any compounded medical non-woven fabrics.
Moreover, hot melt adhesive just has caking property reaching melt at body temperature, thickness will not be made in 1~50um to its use
At inconvenience, mainly by amorphous polyolefin hot melt adhesive, thermoplastic elastomer (TPE) hot melt adhesive, acrylic esters hot-melt glue and polyurethane
One kind of hot melt adhesive etc. is made.
Moreover, the shape of the separation layer is round or rectangle, it is consistent with the collagen protein sponge layer covered, and
Separation layer size is more than or equal to spongy layer；Separation layer with a thickness of 0.5~5mm；Separation layer is by gauze, cotton pad or nonwoven
Cloth pad is made or they are arbitrarily combined.
And this novel collagen wound dressing, the collagen protein sponge of absorbable and degradable guide organization healing, hemostasis, suction
Receive tissue raffinate, collagen protein sponge have good water imbibition can flexible carrying medicament, reduce replacement drug number etc..
Compared with prior art, the benefit of the utility model is.
1. protocollagen wound dressing, fixing layer in conjunction with collagen protein sponge layer so that shape, size combination very
It is flexible, fixing layer can isolate bacterium, moisturizing, and protection wound avoids rubbing, and has fixed function；Absorbable collagen
Film guides organization healing, hemostasis, absorptive tissue raffinate etc.；Realize multi-functional, the compound effective healing for promoting wound of multiple-effect.
2. protocollagen wound dressing, the hot melt adhesive used selects the product of newest hypoallergenic, effectively prevents allergy
The deterioration for causing the condition of the injury, effectively facilitates clinical application.
3. protocollagen wound dressing, for the various humanized shapes of different area and different physical feeling wound designs
Shape and size, can be efficiently using clinically.
4. protocollagen wound dressing, collagen protein sponge layer can first load medicine, reduce dressing, reduce the exposure of wound,
Or make patient by pain when coated medicament.
5. protocollagen wound dressing, the time for reducing operation improves the efficiency of work.
Detailed description of the invention
Fig. 1: the schematic diagram of rectangle dew side collagen wound dressing
Fig. 2: rectangle does not expose edge the schematic diagram of collagen wound dressing
Fig. 3: rectangle reveals side collagen wound dressing A-A sectional view
Fig. 4: rectangle does not expose edge collagen wound dressing B-B sectional view
Fig. 5: big H-type reveals side collagen wound dressing schematic diagram
Fig. 6: small H-type reveals side collagen wound dressing schematic diagram
Fig. 7: ointment type reveals side collagen wound dressing schematic diagram
Fig. 8: character cut in bas-relief Collagen Type VI wound dressing schematic diagram
Specific embodiment
The present invention will be further described with reference to the accompanying drawing and by specific example.
Embodiment 1:
Referring to Fig.1, shown in Fig. 3, a kind of collagen wound dressing, mainly have 1, protective layer 2, adhesive layer 3, release paper 5,
Collagen protein sponge.
The protective layer 1 is the rectangular non-woven cloth made of carbon fiber, with a thickness of 0.06mm；The adhesive layer 2 is
Made of polyurethane hot melt, thickness is in 22 × 10-3mm.
The release paper 3 is with a thickness of 0.02mm.
Wherein collagen protein sponge 5 is to extract I obtained type, III type glue with it by a kind of animal such as pig, ox, sheep, horse, fish
Former albumen is mixed with to obtain collagen gel by being crosslinked.
The collagen protein sponge 5 is obtained through overheat dehydrogenation crosslinking method after collagen solution is freeze-dried
One collagen protein sponge 5 being crosslinked again.
The collagen protein sponge 5 can combine packaging, sterilizing in packaging with fixing layer and release paper 3,
The use of release paper 3 is directly torn when use, collagen protein sponge can also individually be wrapped towards wound with fixing layer and release paper 3
It sterilizes after dress, recombinant uses together when use, first applies collagen protein sponge 5 and sticks wound and applies the fixed protection of fixing layer again.
Wherein, collagen protein sponge 5 is rectangle, and length is consistent with fixing layer, with a thickness of 0.4mm.
Wherein, the porosity of collagen protein sponge 5 is 99%.
The collagen wound dressing, which is characterized in that the fixing layer needs release paper 3 to be covered on before being not used
On the adhesive layer 2 of fixing layer, to protect the viscosity of adhesive layer 2, release paper 4 with a thickness of 0.02mm.
Embodiment 2:
As shown in Figure 2,3, one layer of separation layer 4 is enclosed in embodiment 1 on adhesive layer, the separation layer 4 is viscous
It connects between layer 2 and collagen protein sponge 5, plays a part of to be isolated and absorb diffusate；Separation layer 4 is mainly made of cotton pad, thick
Degree is 2mm.
The spongy layer length is less than fixing layer length.
Embodiment 3:
As shown in Figure 2,3, collagen wound dressing is by 1, protective layer 2, adhesive layer 3, release paper 4, separation layer 5, collagen
Four parts of sponge form.
The protective layer 1 is the rectangular non-woven cloth made of carbon fiber, with a thickness of 0.6mm, the separation layer 4 be
Between adhesive layer 2 and collagen protein sponge 5, play a part of to be isolated and absorb diffusate；It is mainly made of cotton pad, thickness is
2mm。
Wherein collagen protein sponge 5 is to extract I obtained type, III type glue with it by a kind of animal such as pig, ox, sheep, horse, fish
Former albumen is mixed with to obtain collagen solution by being crosslinked.
The collagen protein sponge 5 is after collagen solution is freeze-dried by Chemical Crosslinking Methods obtained one
The collagen protein sponge 5 being crosslinked again.
The collagen protein sponge 5 can combine packaging, sterilizing in packaging with fixing layer and release paper 3,
The use of release paper 3 is directly torn when use, collagen protein sponge can also individually be wrapped towards wound with fixing layer and release paper 3
It sterilizes after dress, recombinant uses together when use, first applies collagen protein sponge 5 and sticks wound and applies the fixed protection of fixing layer again.
Wherein, collagen protein sponge 5 is rectangle, with a thickness of 0.4mm.
Wherein, the porosity of collagen protein sponge 5 is 80%.
The collagen wound dressing, which is characterized in that the fixing layer needs release paper 3 to be covered on before being not used
On the adhesive layer 2 of fixing layer, to protect the viscosity of adhesive layer 2, release paper 3 with a thickness of 0.02mm, release paper is separated two
The structure of layer.
Claims (9)
1. a kind of composite collagen wound dressing, it is characterised in that composite collagen wound dressing by fixing layer, collagen protein sponge and
Release paper composition, the release paper are covered on above collagen protein sponge, and collagen protein sponge is described in the top of fixing layer
Fixing layer is made of protective layer, adhesive layer, and wherein adhesive layer is contacted with collagen protein sponge.
2. composite collagen wound dressing as described in claim 1, fixing layer therein is by protective layer, adhesive layer and separation layer group
At the separation layer is arranged between collagen protein sponge and adhesive layer.
3. composite collagen wound dressing according to claim 2, which is characterized in that the collagen protein sponge is being packed
When, packaging, sterilizing are combined with fixing layer and release paper.
4. composite collagen wound dressing according to claim 2, which is characterized in that the collagen protein sponge and fixing layer
It sterilizes after individually being packed with release paper, recombinant together, first applies collagen protein sponge layer and applies fixing layer again when use.
5. according to any one of the claim 2-4 composite collagen wound dressing, which is characterized in that the release paper is covered on solid
On the adhesive layer of given layer, release paper thickness in monolayer is 10~50um；The release paper can be single or double layer；The bonding
Layer is with a thickness of 1~50um；The protective layer thickness is 0.01~1mm；The separation layer is located at adhesive layer and collagen
Between sponge.
6. according to any one of the claim 2-4 composite collagen wound dressing, which is characterized in that the shape of the separation layer
It is consistent with the collagen protein sponge layer covered, and separation layer size is more than or equal to spongy layer；Separation layer with a thickness of 0.5~
5mm；Separation layer is made of one of gauze, cotton pad or nonwoven cloth pad.
7. according to the described in any item composite collagen wound dressings of claim 2-4, which is characterized in that the shape of the protective layer
Shape has H-shaped, rectangle, circle or spill；The shape of the collagen protein sponge layer has rectangle or circle.
8. composite collagen wound dressing according to claim 1-4, which is characterized in that the collagen sea
It is continuous with a thickness of 0.5~5mm, porosity is 50~99.9%.
9. composite collagen wound dressing according to claim 1-4, which is characterized in that the collagen sea
Load has drug on silk floss.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710720968 | 2017-08-22 | ||
| CN2017107209685 | 2017-08-22 |
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| CN208511564U true CN208511564U (en) | 2019-02-19 |
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| CN201721488965.5U Active CN208511564U (en) | 2017-08-22 | 2017-11-10 | A kind of composite collagen wound dressing |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109675085A (en) * | 2019-02-26 | 2019-04-26 | 百澳瑞派（天津）生物科技有限公司 | A kind of composite collagen dressing and preparation method thereof for burn wound reparation |
| CN109985271A (en) * | 2019-02-26 | 2019-07-09 | 百澳瑞派（天津）生物科技有限公司 | A kind of composite collagen dressing and preparation method thereof for refractory conjunction wound repair |
-
2017
- 2017-11-10 CN CN201721488965.5U patent/CN208511564U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109675085A (en) * | 2019-02-26 | 2019-04-26 | 百澳瑞派（天津）生物科技有限公司 | A kind of composite collagen dressing and preparation method thereof for burn wound reparation |
| CN109985271A (en) * | 2019-02-26 | 2019-07-09 | 百澳瑞派（天津）生物科技有限公司 | A kind of composite collagen dressing and preparation method thereof for refractory conjunction wound repair |
| CN109985271B (en) * | 2019-02-26 | 2021-10-22 | 百澳瑞派（天津）生物科技有限公司 | Composite collagen dressing for healing-difficult wound repair and preparation method thereof |
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