KR101172045B1 - 아포리포단백질 유사체 - Google Patents

아포리포단백질 유사체 Download PDF

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Publication number
KR101172045B1
KR101172045B1 KR1020117004844A KR20117004844A KR101172045B1 KR 101172045 B1 KR101172045 B1 KR 101172045B1 KR 1020117004844 A KR1020117004844 A KR 1020117004844A KR 20117004844 A KR20117004844 A KR 20117004844A KR 101172045 B1 KR101172045 B1 KR 101172045B1
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KR
South Korea
Prior art keywords
delete delete
leu
glu
apolipoprotein
lys
Prior art date
Application number
KR1020117004844A
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English (en)
Korean (ko)
Other versions
KR20110038160A (ko
Inventor
요나스 그라버센
쇠렌 모에스트룹
Original Assignee
에프. 호프만-라 로슈 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 에프. 호프만-라 로슈 리미티드 filed Critical 에프. 호프만-라 로슈 리미티드
Priority claimed from PCT/DK2001/000739 external-priority patent/WO2002038609A2/en
Publication of KR20110038160A publication Critical patent/KR20110038160A/ko
Application granted granted Critical
Publication of KR101172045B1 publication Critical patent/KR101172045B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020117004844A 2000-11-10 2001-11-09 아포리포단백질 유사체 KR101172045B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
DKPA200001682 2000-11-10
DKPA200001682 2000-11-10
DKPA200100057 2001-01-15
DKPA200100057 2001-01-15
US26402201P 2001-01-26 2001-01-26
US60/264,022 2001-01-26
PCT/DK2001/000739 WO2002038609A2 (en) 2000-11-10 2001-11-09 Apolipoprotein conjugates

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020037006365A Division KR101034901B1 (ko) 2000-11-10 2001-11-09 아포리포단백질 유사체

Publications (2)

Publication Number Publication Date
KR20110038160A KR20110038160A (ko) 2011-04-13
KR101172045B1 true KR101172045B1 (ko) 2013-05-14

Family

ID=42813922

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020117004844A KR101172045B1 (ko) 2000-11-10 2001-11-09 아포리포단백질 유사체
KR1020037006365A KR101034901B1 (ko) 2000-11-10 2001-11-09 아포리포단백질 유사체

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020037006365A KR101034901B1 (ko) 2000-11-10 2001-11-09 아포리포단백질 유사체

Country Status (6)

Country Link
KR (2) KR101172045B1 (da)
AT (1) ATE482232T1 (da)
DE (1) DE60143122D1 (da)
DK (1) DK1335938T3 (da)
PT (1) PT1335938E (da)
SI (1) SI1335938T1 (da)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999016459A1 (en) 1997-09-29 1999-04-08 Dasseux Jean Louis Apolipoprotein a-i agonists and their use to treat dyslipidemic disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999016459A1 (en) 1997-09-29 1999-04-08 Dasseux Jean Louis Apolipoprotein a-i agonists and their use to treat dyslipidemic disorders

Also Published As

Publication number Publication date
SI1335938T1 (sl) 2011-01-31
DK1335938T3 (da) 2010-12-13
KR20030048138A (ko) 2003-06-18
PT1335938E (pt) 2010-12-22
ATE482232T1 (de) 2010-10-15
KR20110038160A (ko) 2011-04-13
DE60143122D1 (de) 2010-11-04
KR101034901B1 (ko) 2011-05-17

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