KR101004662B1 - 에너지 항상성에 관여하는 신규한 펩티드 - Google Patents
에너지 항상성에 관여하는 신규한 펩티드 Download PDFInfo
- Publication number
- KR101004662B1 KR101004662B1 KR1020087005454A KR20087005454A KR101004662B1 KR 101004662 B1 KR101004662 B1 KR 101004662B1 KR 1020087005454 A KR1020087005454 A KR 1020087005454A KR 20087005454 A KR20087005454 A KR 20087005454A KR 101004662 B1 KR101004662 B1 KR 101004662B1
- Authority
- KR
- South Korea
- Prior art keywords
- swirl
- mice
- seq
- delete delete
- obesity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2264—Obesity-gene products, e.g. leptin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Marine Sciences & Fisheries (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70594005P | 2005-08-05 | 2005-08-05 | |
| US60/705,940 | 2005-08-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20080042866A KR20080042866A (ko) | 2008-05-15 |
| KR101004662B1 true KR101004662B1 (ko) | 2011-01-03 |
Family
ID=37727967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020087005454A Expired - Fee Related KR101004662B1 (ko) | 2005-08-05 | 2006-08-07 | 에너지 항상성에 관여하는 신규한 펩티드 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US20090253619A1 (enExample) |
| EP (1) | EP1928487A4 (enExample) |
| JP (1) | JP2009502208A (enExample) |
| KR (1) | KR101004662B1 (enExample) |
| CN (1) | CN101505786A (enExample) |
| AU (2) | AU2006278406B2 (enExample) |
| CA (1) | CA2618047C (enExample) |
| IL (2) | IL189065A (enExample) |
| RU (2) | RU2409590C2 (enExample) |
| WO (1) | WO2007019426A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011140296A1 (en) | 2010-05-05 | 2011-11-10 | Infinity Pharmaceuticals | Triazoles as inhibitors of fatty acid synthase |
| EP3159331A1 (en) | 2010-05-05 | 2017-04-26 | Infinity Pharmaceuticals, Inc. | Tetrazolones as inhibitors of fatty acid synthase |
| US11246912B2 (en) * | 2017-08-30 | 2022-02-15 | Hadasit Medical Research Services & Development Ltd. | Methods for treating and diagnosing metastatic liver cancer |
| US11969460B2 (en) * | 2018-06-08 | 2024-04-30 | Saint Louis University | Methods and compositions for treating decreased cognitive ability |
| CN110028570A (zh) * | 2018-10-31 | 2019-07-19 | 华中科技大学 | 一种肌肉素的表达方法及其在代谢疾病中的应用 |
| WO2024263938A2 (en) * | 2023-06-23 | 2024-12-26 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Using enho gene therapy to treat cardiometabolic disease |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030096951A1 (en) | 1998-08-14 | 2003-05-22 | Kenneth Jacobs | Secreted proteins and polynucleotides encoding them |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2078345C1 (ru) * | 1992-04-03 | 1997-04-27 | Аникеева Светлана Петровна | Способ получения сывороточного белкового препарата, влияющего на активность окислительно-энергетического обмена |
| WO2000009552A1 (en) * | 1998-08-14 | 2000-02-24 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
| US6783969B1 (en) * | 2001-03-05 | 2004-08-31 | Nuvelo, Inc. | Cathepsin V-like polypeptides |
-
2006
- 2006-08-07 WO PCT/US2006/030686 patent/WO2007019426A2/en not_active Ceased
- 2006-08-07 JP JP2008525274A patent/JP2009502208A/ja active Pending
- 2006-08-07 EP EP06800865A patent/EP1928487A4/en not_active Withdrawn
- 2006-08-07 AU AU2006278406A patent/AU2006278406B2/en not_active Ceased
- 2006-08-07 RU RU2008108509/13A patent/RU2409590C2/ru not_active IP Right Cessation
- 2006-08-07 CA CA2618047A patent/CA2618047C/en not_active Expired - Fee Related
- 2006-08-07 KR KR1020087005454A patent/KR101004662B1/ko not_active Expired - Fee Related
- 2006-08-07 CN CNA2006800359751A patent/CN101505786A/zh active Pending
-
2008
- 2008-01-28 IL IL189065A patent/IL189065A/en not_active IP Right Cessation
- 2008-02-05 US US12/012,627 patent/US20090253619A1/en not_active Abandoned
-
2010
- 2010-05-14 RU RU2010119559/10A patent/RU2010119559A/ru not_active Application Discontinuation
- 2010-06-22 AU AU2010202600A patent/AU2010202600B2/en not_active Ceased
- 2010-08-02 US US12/848,308 patent/US8518892B2/en not_active Expired - Fee Related
- 2010-08-24 IL IL207764A patent/IL207764A0/en unknown
-
2013
- 2013-03-26 US US13/850,806 patent/US20130231280A1/en not_active Abandoned
-
2015
- 2015-10-26 US US14/922,557 patent/US20160102126A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030096951A1 (en) | 1998-08-14 | 2003-05-22 | Kenneth Jacobs | Secreted proteins and polynucleotides encoding them |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006278406A1 (en) | 2007-02-15 |
| CA2618047C (en) | 2015-04-14 |
| US20160102126A1 (en) | 2016-04-14 |
| IL189065A (en) | 2012-10-31 |
| WO2007019426A2 (en) | 2007-02-15 |
| RU2010119559A (ru) | 2011-11-20 |
| AU2010202600A1 (en) | 2010-07-15 |
| US20130231280A1 (en) | 2013-09-05 |
| EP1928487A4 (en) | 2009-11-04 |
| US8518892B2 (en) | 2013-08-27 |
| CA2618047A1 (en) | 2007-02-15 |
| AU2006278406B2 (en) | 2010-03-25 |
| WO2007019426A3 (en) | 2009-04-23 |
| CN101505786A (zh) | 2009-08-12 |
| IL189065A0 (en) | 2008-08-07 |
| IL207764A0 (en) | 2010-12-30 |
| KR20080042866A (ko) | 2008-05-15 |
| RU2008108509A (ru) | 2009-09-10 |
| AU2010202600B2 (en) | 2012-07-19 |
| US20090253619A1 (en) | 2009-10-08 |
| JP2009502208A (ja) | 2009-01-29 |
| US20100299769A1 (en) | 2010-11-25 |
| RU2409590C2 (ru) | 2011-01-20 |
| EP1928487A2 (en) | 2008-06-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| PA0105 | International application |
St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
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| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
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| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
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| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
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| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
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| E13-X000 | Pre-grant limitation requested |
St.27 status event code: A-2-3-E10-E13-lim-X000 |
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| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
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| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
St.27 status event code: A-1-2-D10-D22-exm-PE0701 |
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| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
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| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U12-oth-PR1002 Fee payment year number: 1 |
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| PG1601 | Publication of registration |
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| FPAY | Annual fee payment |
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| LAPS | Lapse due to unpaid annual fee | ||
| PC1903 | Unpaid annual fee |
St.27 status event code: A-4-4-U10-U13-oth-PC1903 Not in force date: 20151223 Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE |
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St.27 status event code: N-4-6-H10-H13-oth-PC1903 Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE Not in force date: 20151223 |