KR100974584B1 - Health assistance food included the euphorbia humifusa wild and the manufacturing method therof - Google Patents

Abstract

PURPOSE: Health supplementary food containing Euphorbia Humifusa willd and a manufacturing method thereof are provided to make the health supplementary food made of Euphorbia Humifusa willd as a main material without toxicity. CONSTITUTION: A manufacturing method of health supplementary food containing Euphorbia Humifusa willd includes a step for putting Euphorbia Humifusa wild, ginseng, Angelica sinensis, Phellinus linteus, Glycyrrhiza uralensis and jujube with a weight ratio of 1 : 0.02 ~ 0.1 : 0.02 ~ 0.1 : 0.01 ~ 0.05 : 0.02 ~ 0.1 : 0.05 ~ 0.2, respectively and a step for extracting materials in water for 1 ~ 4 hours in 100 ~ 120 °C.

Description

HEALTH ASSISTANCE FOOD INCLUDED THE EUPHORBIA HUMIFUSA WILD AND THE MANUFACTURING METHOD THEROF}

The present invention relates to a dietary supplement comprising a bedbug, and to a method of manufacturing the same, and more particularly, to a dietary supplement that is harmless to a human body and is beneficial to the human body using a bedbug useful as a main ingredient.

The dietary structure is undergoing a change in the socioeconomic environment, such as nuclear familyization, individualization, population growth at night, the age of mass consumption, diversification of consumption patterns, the pursuit of convenience, and the increase of women's social entry.

This change of consciousness about the composition of meals and the increasing demand of consumers for simple foods began to appear as a tendency to seek convenience.

However, such modern eating habits are likely to lead to malnutrition due to malnutrition, overnutrition and incorrect nutrition information.

Malnutrition due to malnutrition causes various diseases such as anemia, and excessive intake of nutrients causes overweight and obesity, which are emerging as a health problem today, and further develop chronic degenerative diseases such as arteriosclerosis, diabetes, and high blood pressure. Weighted.

In addition, serious conditions, such as the development of various cancers, malignant tumors, heart disease, kidney disease, etc. and shortened lifespan have been reached.

Many functional supplements have been introduced to help prevent and treat various diseases.

Recently, as well as the prevention of disease as well as the health (Wellbeing) wind and attention to health is increasing more and more people are changing the constitution and no side effects, using the herbal supplements are sold a lot of health supplements.

However, most of the herbal medicines because of the unique bitterness and sour taste of the herbal medicine, even if you know the goodness of the herbal medicine to avoid taking.

In addition, due to the toxicity and properties of the herbal medicine itself, care should be taken when mixing the herbal medicines, and additional pretreatment to neutralize the toxicity, otherwise side effects may occur.

In addition, the health supplement foods using ground bedbugs beneficial to the human body of herbal medicines has not been developed yet.

In the present invention, to solve the above problems, there is an object to provide a health supplement food that is harmless to the human body as a main raw material is not toxic and useful to the human body.

In the manufacturing method of the health supplement foods, including the earthworm bed of the present invention, the step of preparing the material by selecting each of the earthworm ( Euphorbia Humifusa wild ), ginseng, Angelica, situation mushrooms, licorice, jujube and the selected ingredients in a container It is put, and water is put here and is configured to include the step of extracting for 1 to 4 hours at 100 ~ 120 ℃.

In addition, during the extracting step, it is good to put the ground bug, ginseng, Angelica, situation mushroom, licorice, jujube 1: 1: 0.02 ~ 0.1: 0.02 ~ 0.1: 0.01 ~ 0.05: 0.02 ~ 0.1: 0.05 ~ 0.2 by weight .

According to the present invention, a beneficial health supplement food is provided that is harmless to the human body with the main raw material useful for the human body.

1 is a manufacturing method of the dietary supplement containing the ground bag of the present invention.

Referring to the manufacturing method of the health supplement food including the ground bug of the present invention.

1) Material Preparation Step

Prepare by selecting land bedbug, ginseng, donkey, situation mushroom, licorice and jujube.

Euphor bia humifusa is an annual herb that accompanies the Great Family , and is a common plant growing in grass, yard, and road .

It is the main ingredient of flavonoids and saponins, and leaves contain more than 10% of tannins, and contain glutinous assets, methyl esters, maculaton, cytosterols, alkaloids, etc. It is known that.

In addition, it is said that herbal medicine is effective for dysentery, diarrhea, gastritis, colitis, cold cough, bloody stool, hemorrhage, uterine bleeding, hematuria, gum inflammation, shingles, and sore throat.

Ginseng (Panax ginseng CAMey., Ginseng) is a medicinal ingredient such as saponin, panacene, panaquilon and panaxin, as well as proteins, nucleic acids, essential fatty acids and essential amino acids. Containing various nutrients such as minerals, vitamins and sugars, and choline, it is a valuable resource as well as medicinal foods.

Ginseng has long been used as a medicine to promote metabolism and tonic action of the human body. According to Chinese medicine, ginseng stabilizes nerves, increases resistance to stress stimuli, strengthens blood sugar and strengthens immunity. The effect is very good.

Danggui (當歸) is a perennial perennial plant of the family Apiaceae, in which oriental medicine is used as a medicinal root, which is used for anemia and gynecological diseases as a warming pill, pain pill, sedative, tonic.

Phellinus linteus ( Phellinus linteus ) is a rare perennial mushroom that grows in the alpine tree, such as wild mulberry, oak, chestnut, and oak, and is often called "wood mud."

These situation mushrooms contain polysaccharides in addition to the components of potassium, calcium, magnesium, vitamins B2, B3, C, and fibrous amino acids, which have been known to have an immunoactive effect.

Licorice (licorice root) is a perennial herb of the dicotyledonous plant Rosaceae, in oriental medicine, licorice root is used as a medicinal herb, which has sputum cutting effect, alleviation effect, anti-inflammatory effect, anti-inflammatory effect, antihistamine effect, and so on. It is also used as a taste and aggression medicine, and widely used in poisonous medicines, excipients, gastroduodenal ulcers, Addison's disease, bronchial asthma, jaundice and hepatitis, eczema and other skin diseases.

Date is the fruit of Zizyphus jujuba var. Inermis, and is used as a diuretic, tonic, and emollient in Chinese medicine.

2) extracting step

The selected ingredients are put in a container, water is added thereto, and hot water extraction is performed at 100 to 120 ° C. for 1 to 4 hours to prepare health supplement food.

In addition, during the extraction, it is good to extract the ground bug, ginseng, Angelica, situation mushroom, licorice, jujube 1: 0.02 ~ 0.1: 0.02 ~ 0.1: 0.01 ~ 0.05: 0.02 ~ 0.1: 0.05 ~ 0.2 by weight.

In other words, the present inventors have studied using a number of herbal ingredients, the main raw material of the anti-cancer, detoxification, antibacterial action, soothing action, ginseng, Angelica, situation mushroom, licorice, jujube When extracted, it was found that the health supplements that are beneficial to the human body are prepared for reflux esophagitis, gastritis, colitis, and hangover without any side effects.

Hereinafter, the present invention will be described in detail with reference to Examples and Experimental Examples, but these do not limit the scope of the present invention.

Example 1 Preparation of Health Supplement Food 1 Including the Bedbug of the Present Invention

Euphorbia Humifusa wild , ginseng, Angelica, situation mushroom, licorice and jujube were prepared by selection.

The selected ground bedbug 20g, ginseng 0.5g, Angelica 0.5g, situation mushroom 0.3g, licorice 0.5g, jujube 1.5g into a container, 1000cc of water and extracted for 3 hours at 110 ℃ for health supplement food 1 Was prepared.

Example 2 Preparation of Health Supplement Food 2 Including the Bedbug of the Present Invention

Euphorbia Humifusa wild , ginseng, Angelica, situation mushroom, licorice and jujube were prepared by selection.

The selected land bedbug 20g, ginseng 1.5g, Angelica 1.5g, situation mushroom 1.0g, licorice 1.5g, jujube 2.5g into a container and put 1000cc of water and extracted for 3 hours at 110 ℃ health supplement food 2 Was prepared.

Comparative Example 1 Preparation of Health Supplement

Euphorbia Humifusa wild was prepared by selection.

20 g of the selected ground bedbugs were put in a container, and 1000 cc of water was added thereto, followed by extraction at 110 ° C. for 3 hours to prepare a health supplement.

Experimental Example 1 Toxicity Measurement of Euphorbia Humifusa wild

To confirm the toxicity of Euphorbia Humifusa wild , the main ingredient of the present invention, the toxicity appeared when oral administration of the dietary supplement 1, the main raw material of Example 1 for 2 weeks, using rats from the Korea Testing and Research Institute Response evaluation was carried out, and basically was performed in accordance with Korean Food and Drug Administration Notice No. 2005-60, "Toxicity Test Standard for Drugs, etc.".

Experimental method and results are as follows.

1. Experimental method

SD rats were orally administered to the male and female rats for 5 weeks for 2 weeks.

The dose of the test substance (Health supplement foods with the main raw material of Example 1) was set at 62.5, 125, 250 mg / kg / day, and only the excipient was administered to the control group.

Clinical symptoms, weight gain and feed consumption were observed during the administration of the test substance. At the end of the administration, urine, hematological and hematological tests were performed on all animals.

In addition, organs were visually examined for organs at necropsy.

2. Experimental Results

During the test period, in the control group and animals of all test groups, hair growth, sensitive response, and aggressive behavior were observed from day 8 after administration, but all recovered on day 11, and no dead animals were observed.

In addition, no significant changes were observed in weight change, feed, negative intake urine test, and hematological test. However, blood biochemical test showed significant changes in ALP, BUN, and IP measurements in males compared to controls. The case showed a significant change in Cholesterol, IP, Na and Cl measurements.

However, this does not correlate with females, and since the measurement is within the normal range, it is not considered to be a change by administration of the test substance.

In autopsy findings, polyps were observed in the small intestine in control and all test animals, but this was observed in all cases and it is considered that the effect of excipient is not test substance.

From the above results, oral dosing for 2 weeks at 62.5, 125, and 250 mg / kg / day was found to have no significant toxicological change until the highest dose of 250 mg / kg / day. NOAEL; No Observed Adverse Effect Level) is determined to be greater than 250 mg / kg / day.

Experimental Example 2 Clinical Survey

The dietary supplements prepared in Example 1 were examined in a total of 20 adults and 5 adults of 20s to 50s, who commonly complain of gastritis, reflux esophagitis, and fatigue.

For comparison, we used commercially available health supplements (health supplements related to gastritis improvement, health supplements related to reflux esophagitis and fatigue recovery tonic).

At this time, twice daily, 200 ml each time to take 30 days, and then questionnaire.

The degree of the effect was responded according to the five-point method, and the average was shown in Table 1 below (average * symbol; 1. No effect at all, 3. Moderate., 5. The effect was very good. .)

Gastritis improvement Reflux esophagitis improvement Fatigue Recovery Example 1 4.1 4.2 4.1 Example 2 5 4.8 5 comparison target 2.7 2.5 1.9

As shown in Table 1, the comparison subjects can confirm some improvement effects should be taken at least three months, while the health supplement according to Example 1 of the present invention in gastritis improvement, reflux esophagitis improvement, fatigue recovery, etc. It can be seen that the effect.

Experimental Example 3 Investigation on Hangover Relief

The alcohol concentration of the prepared liquor was measured using a spirit meter.

Thereafter, after preparing the glass bottle, 100 ml of the following alcohols were added, and the same amount of the health supplement of Example 2 was shaken to be uniformly mixed, and after about 12 hours, the alcohol concentration was measured using a spirit meter.

beer Soju Alcohol consumption
(Ml) 100 100 Alcohol concentration in alcohol
(%) 5 19 Mixing amount of Example 2
(Ml) 100 100 Alcohol concentration after mixing Less than 1% Less than 3%

In the experimental result, the health supplement 2 of Example 2 was mixed with the alcohol and after 12 hours to determine the alcohol concentration was confirmed that the alcohol concentration is lowered.

Therefore, it was found that the health supplement foods including the landslides of the present invention have an effect on relieving hangovers.

Experimental Example 3 Sensory Test

The health and food supplements 1 and 2 of the present invention configured as described above and the health supplements of Comparative Example 1 were examined for the aroma and taste to investigate the overall consumer satisfaction.

In consideration of age and gender, a total of 20 males and females in their 20s to 50s were surveyed for each age group, and the overall consumer satisfaction was examined by comparing the flavors and tastes.

As a result, it is shown in Table 3 below.

flavor incense Consumer satisfaction Example 1 4.1 4.2 4.1 Example 2 5 4.8 5 Comparative Example 1 3.5 3.3 3.4

* Preference degree; 1. Very bad., 3. It is normal., 5. Very good.

As shown in Table 3, the health supplement food of Comparative Example 1 was extracted only by hot water, and the herbal medicine itself had a bitter taste or a somewhat difficult point to be easily used by consumers. And the health supplement of Example 2 is well matched with various herbal medicines almost no bitter and sour taste and good taste and aroma can be easily used by consumers, the overall customer satisfaction was confirmed to be high.

Thus, it was confirmed that through the method of manufacturing the health supplement food of the present invention solves the problems of the health supplement food using the existing herbal medicines and at the same time the health supplement foods beneficial to the human body is produced.

Claims (3)

Preparing ingredients by selecting Euphorbia Humifusa wild , ginseng, Angelica, situation mushroom, licorice and jujube respectively; And
Put the selected materials in a container, water is added to it and extracting hot water for 1 to 4 hours at 100 ~ 120 ℃; comprising,
Method of manufacturing health supplements, including ground bedbugs. The method of claim 1,
In the step of extracting, extract the ground bug, ginseng, Angelica, situation mushroom, licorice, jujube 1: 0.02 ~ 0.1: 0.02 ~ 0.1: 0.01 ~ 0.05: 0.02 ~ 0.1: 0.05 ~ 0.2 by weight ,
Method of manufacturing health supplements, including ground bedbugs. It consists of hot water extraction of mixed material mixed with ground bean, ginseng, donkey, situation mushroom, licorice, jujube in a ratio of 1: 0.02 ~ 0.1: 0.02 ~ 0.1: 0.01 ~ 0.05: 0.02 ~ 0.1: 0.05 ~ 0.2 with water,
Health supplements, including landslides.

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