KR100953998B1 - A centrige installing the front of injector - Google Patents

Abstract

Centrifugal separator for centrifugal mounting of the syringe tip of the present invention is a centrifugal separator using a fat stem cell extraction syringe, the centrifuge is formed in a multi-stage receiving hole for accommodating the syringe body and the receiving hole for receiving the flanger in the centrifuge The lower end of the syringe body is seated on the step while the needle inlet of the syringe is mounted upwardly from the mounting hole so that a step is formed at the boundary between the mounting hole and the receiving hole. And a syringe receptacle, which can be used.

Liposuction, centrifugation, syringe, fat stem cell

Description

A centrige installing the front of injector}

The present invention relates to a centrifuge, and more particularly to a centrifuge for the centripetal mounting of the syringe tip.

Liposuction is a surgical method to correct the shape of the body, a means for replacing the volume of the soft tissue in the human body, and is a method that is variously used for cosmetic purposes such as facial wrinkle removal or depression treatment.

Liposuction is not a process of using fats obtained by liposuction, but rather separating only living fat cells through centrifugation and washing. Unlike oil from broken fat cells and blood from inhalation causes necrosis of nearby transplanted adipose tissue, technology that separates only living fat cells is introduced to dramatically improve survival.

The fat graft procedure involves making a small incision in the body, inserting a tube with a hole at the end (liposuction tube) and sucking the fat using the negative pressure of the syringe.

Subsequently, a centrifugal separator separates liquid components such as fat stem cells, erythrocytes, blood, and moisture from the fat collected in the syringe into layers, and then free oil freed from the erythrocytes and broken fat cells separated between layers in the syringe. (Free oil) is removed, and the procedure is performed to obtain only the stem cells to be transplanted and inject into the human body.

In order to do this, the syringe with the fat extracted in a positive pressure is placed in a test tube for centrifuge, and the test tube is mounted in a centrifuge and rotated at a high speed to separate the fatty material according to the size and density of the particles, thereby making the material different in specific gravity from the fat component. Separate them (red blood cells, pre-oil).

Here, centrifugation uses the difference in density between the solid and the liquid surrounding the solid. Some mixture is placed in a test tube and rotated rapidly to give artificially strong acceleration, allowing heavy material to sink below the test tube and light material to float above it.

That is, as the inhaled fat is subjected to centrifugation, as shown in FIG. 1, in the test tube, red blood cells E are located at the bottom layer, and the top layer is pre-oil F, and is located between the red blood cells E and pre-oil F. Adipose stem cell S is divided into layers.

Thereafter, only the stem cells S are extracted from the test tube through a syringe equipped with a needle.

However, the prior art has a problem that the secondary infection due to the risk of microbial contamination may occur as the fat extracted in the process of transferring to the test tube through the syringe to extract the first fat.

In addition, due to the disadvantage of using expensive equipment such as a clean bench or a clean room in order to prevent the risk of such contamination, the apparatus and method for acquiring fat stem cells S have a complicated and difficult problem.

In addition, when only the fat stem cell S is extracted in a test tube, foreign substances may be introduced and exposed to the outside air, which may cause a secondary infection caused by air or foreign substances, thus making it difficult to perform aseptic extraction process. .

This requires time and labor in the extraction method of fat stem cells S, there is a risk of losing pure fat and infection due to air contact.

Accordingly, it is an object of the present invention to provide a centrifuge that can maximize the prevention of air exposure of the active ingredient in the fat extracted from the body.

It is also an object of the present invention to provide a centrifugal separator centrifuge for mounting on an angle-variable centrifuge and a fixed centrifuge.

In addition, it is an object of the present invention to provide a centrifuge for mounting a syringe centrifugal to be mounted regardless of the size of the lipograft syringe.

In addition, an object of the present invention is to be inversely proportional to the centripetal force and centrifugal force in the syringe by selectively limiting the centripetal angle of the syringe which is converted to the centripetal direction by the centrifugal force while being interlocked according to the rotation of the angle-variable centrifuge. It is to provide a syringe centrifuge centrifuge to be adjustable.

In order to achieve the above object, the centrifugal separator for centrifugal mounting of the syringe tip of the present invention is a device for centrifugation using a syringe for extracting fat stem cells, and the accommodating body accommodates a mounting hole and a flanger for accommodating the syringe barrel in the centrifuge. The ball is formed in multiple stages, and a step is formed at the boundary between the mounting hole and the receiving hole so that the needle inlet of the syringe is mounted upwardly from the mounting hole, and the lower end of the syringe body is seated on the step. Provided is a centrifuge comprising a syringe receptacle that can be positioned at the tip of the syringe.

According to the present invention, the centrifugal separator is provided with at least one clamp installed around the rotor interlocking with the rotating device, and hinge-coupled to the clamp a separate bucket provided with a syringe receiving portion therein to provide an angle-variable centrifuge. .

In addition, the present invention is formed by a pair of forks, the clamp is formed in order to sequentially form a coupling hole corresponding to the surface facing each other, and coupled to any one of the coupling holes across the support pin The outer periphery of the bucket hinged to the clamp is provided to provide a centrifuge for mounting the centrifugal direction of the tip of the syringe configured to limit the inclination angle of the bucket.

In another aspect, the present invention provides a centrifuge for the centripetal mounting of the syringe tip formed with guide grooves on both sides of the inner circumference of the mounting hole of the bucket so that the support piece formed at the syringe body end.

In another aspect, the present invention the bucket is cut in a pair of interposition grooves downward from the upper end on the outer periphery, the opposite face of the interposition grooves to form a pin hole in a vertical downward in order to correspond to any one of the pin holes It provides a centrifuge for the centripetal mounting of the tip of the syringe formed to support the backing portion of the syringe by coupling the locking pin to the pin hole of the.

In another aspect, the present invention provides a centrifuge for mounting the centrifugal direction of the tip of the syringe made so that the rotation angle of the bucket can be inclined angle around the center in the range 20 ~ 80 °.

In another aspect, the present invention provides a centrifugal separator for centrifugal direction of the syringe tip provided with at least one syringe receiving portion having the same angle as the slope inside the rotor to apply to a fixed centrifuge equipped with a rotor formed with a slope around the centrifuge To provide.

 In addition, the present invention has a semi-circular cross-section to be applied to the centrifuge equipped with a rotor formed with a slope around the center of the centrifuge and detachably coupled to one side of the syringe receiving portion open to the slope, half the arc in the syringe receiving portion It provides a centrifugal separator for the centripetal mounting of the syringe tip to form a locking groove on both sides of the mounting hole of the shape so that the bent both ends of the clip having elasticity can be fitted to grip the syringe body.

As described above, the centrifugal separator for the centrifugal mounting of the syringe tip of the present invention has a tip (needle inlet) of the center of rotation of the centrifuge when the syringe extracting fat from the inside of the syringe is mounted on the centrifuge. It is placed in the centripetal direction so that the material with low specific gravity during the high-speed rotation of the centrifuge can be positioned closer to the inlet side of the needle.Easily remove the preoil by positive pressure operation of the syringe. By extracting without being exposed, there is an effect that the aseptic extraction process can be easily performed.

In addition, the centrifuge for mounting the centrifugal direction of the syringe tip of the present invention can be mounted to the angle-variable centrifuge and the fixed centrifuge of the centrifuge, so that the compatibility of the mounting of the means for mounting the syringe tip in the centripetal direction It has the effect of improving.

In addition, the centrifugal separator for centrifugal mounting of the syringe tip of the present invention can be used universally regardless of the size of the lipograft syringe, thereby providing convenience of centrifugal separation.

In addition, the centrifuge for mounting the centrifugal direction of the syringe tip of the present invention can be selectively linked with the rotation of the angle-variable centrifuge to selectively limit the centripetal angle of the syringe is converted to the centripetal direction by centrifugal force centrifugation According to the type of the extract to be adjusted by inversely adjusting the size of the centripetal force and centrifugal force in the syringe, there is an effect to create an optimal centrifugation environment according to the extraction target.

Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings.

First, in the drawings, the same components or parts are to be noted that the same reference numerals as possible. In describing the present invention, detailed descriptions of related known functions or configurations are omitted in order not to obscure the subject matter of the present invention.

Figure 2 is a perspective view showing the interlaminar structure of the fat cells centrifuged through the present invention in the syringe, Figure 3 is a perspective view showing an angle-variable centrifuge of the centrifuge of the present invention, Figure 4 is a variable angle centrifugal of the present invention Figure 5 is a perspective view showing a bucket of the separator, Figure 5 is a cross-sectional view showing a bucket of the variable angle centrifuge of the present invention, Figure 6 is a perspective view showing a first embodiment of a bucket of the variable angle centrifuge of the present invention, Figure 7 Is a perspective view showing a second embodiment of the bucket of the variable centrifuge of the present invention, Figure 8 is a partially enlarged perspective view showing the mounting state of the bucket in the angle-variable centrifuge of the present invention, Figure 9 is a centrifuge of the present invention Is a perspective view showing a fixed centrifuge of the middle, Figure 10 is a perspective view showing another embodiment of the fixed centrifuge of the present invention, 11 is a cross-sectional view showing a syringe mounted state of another embodiment of a stationary centrifuge of the present invention.

Typically, the centrifuge 100 is provided with a rotor 120 that receives a rotational force of a motor (not shown), and the rotor 120 is provided with a slope 121 or a clamp 130.

Here, the centrifuge 100 clamps the bucket 140 which can be equipped with a fixed centrifuge 100b for mounting a syringe 10 directly to the periphery of the rotor 120 and a clamp 130 mounted radially to the rotor 120 to mount the syringe 10. It is divided into a variable angle centrifuge 100a rotatably coupled to 130.

As described above, the centrifuge 100 may rotate the bucket 140 or the slope 121 at a high speed by the rotation of the rotor 120 to separate the materials according to the size and density of the extract (fat cell) extracted in the syringe.

That is, the slope 121 or the bucket 140 generates centripetal force at the tip of the syringe 10 (needle inlet) mounted by the high-speed rotation of the rotor 120, and the centrifugal force is applied to the lower portion so that the supernatant in the syringe 10 is made of a relatively small size and density material. Layered, relatively large in size and density precipitates into the supernatant.

Here, the distal end of the syringe 10 is mounted upward in the centrifuge 100 so that the distal end of the syringe 10 becomes the center of centripetal force when the centrifuge 100 operates at high speed.

As shown in Figure 3 or 9, the centrifuge 100 of the present invention is formed so that the front end portion of the syringe 10 can be mounted upward, the specific gravity is generated while centripetal force and centrifugal force are generated in the upper and lower portions of the syringe 10 by high-speed rotation, respectively The lower the material, the layer is formed closer to the tip of the syringe 10 acting the centripetal force, the closer to the flanger 12 side of the lower syringe 10, the centrifugal force acts so that the high specific gravity material layer is separated and laminated.

As shown in FIG. 2, red blood cells E are located at the bottom of the syringe according to the specific gravity of fat extracted from the body, and preoil F is positioned at the tip of the syringe, which is the uppermost layer, between the red blood cells E and the pre-oil F. Adipose stem cells S consists of a separate layer.

To this end, in the centrifuge 100, the mounting hole 151 for accommodating the syringe barrel 11 and the receiving hole 152 for accommodating the flanger 12 are formed in multiple stages so that the stepping hole 153 is formed at the boundary between the mounting hole 151 and the receiving hole 152. Prepare to keep the lower end of the syringe barrel 11 stuck to the step 153.

Here, the lower end of the syringe barrel 11 is engaged with the step 153, and the distal end of the syringe 10 becomes the center of centripetal force.

In particular, the support piece 133 of the syringe 100 or the end of the syringe barrel 11 is caught on the step 153 because of the structure of the centrifuge 100 being pushed to the rear of the mounting hole 151 by the centrifugal force acting on the syringe barrel 11 during the high-speed rotation of the centrifuge 100. This is to prevent a change in volume due to a positive pressure between the space and the flanger 12.

Therefore, the syringe barrel 11 is held in a locking structure at the step 153 to be mounted without flow at the inner circumference of the mounting hole 151, thereby allowing the centrifugation to be stably performed.

As shown in FIG. 3 or 9, the centrifuge 100 is divided into an angle-variable centrifuge 100a and a fixed centrifuge 100b according to the type.

First, the configuration of the centrifugal centrifuge 100a for centripetal mounting of the angle syringe tip shown in FIGS. 3 to 5 is as follows.

First, the variable centrifuge 100 is provided with a rotating device 110 that receives a rotational force to the motor (not shown), and at least one clamp 130 installed around the rotor 120 in conjunction with the rotating device 110, the inside of the syringe receiving The detachable bucket 140 having the portion 150 is hinged to the clamp 130.

In addition, the bucket 140 has a mounting hole 151 and a receiving hole 152 formed in multiple stages by a syringe accommodating part 150 provided therein, and a step 153 is formed at a boundary thereof.

The mounting hole 151 is coupled to the syringe barrel 11 so that the lower end of the syringe barrel 11 is held by the step 153 and the flanger 12 is accommodated in the accommodation hole 152.

And, the clamp 140 in the clamp 130 is detachably coupled, the rotation of the up and down in the clamp 130 is free, the angle of the bucket 140 in the clamp 130 by the centripetal force and centrifugal force generated during the high-speed rotation of the centrifuge 100 Is converted.

During the centrifugation process, the syringe 100 centrifuged stably fat without changing the volume of the internal space, and layered downward from the top of the syringe in the order of low oil specific materials, preoil F, fat stem cell S, and red blood cell E. Are distinguished.

Then, the centrifuged syringe 10 is taken out of the bucket 140 and then the flanger 12 is positively extracted to extract the pre-oil F located close to the inlet of the syringe, and then the external layer can be easily removed without exposing the lower stem cell S to the outside air. Aseptic extraction process can be easily performed.

As shown in FIG. 8, the clamp 130 is formed as a pair of forks 131 to sequentially form a coupling hole 132 formed to correspond to the surface facing each other, the coupling of any one of the coupling holes 132 Engage across the support pin 133 to the ball 132.

Here, the support pin 133 is selectively coupled to any one of the coupling holes 132 sequentially formed, so that the upper outer circumference of the bucket 140 is caught during high speed rotation, thereby adjusting the angular displacement of the bucket 140.

That is, when the bucket 140 rotated by the centrifuge 100 is changed upward by the centrifugal force, the upper end of the outer circumference of the bucket 140 is caught by the support pin 133 and no longer generates an angular displacement.

As a result, the angle of the bucket 140 may be adjusted according to the type of the centrifugal object to properly adjust the centrifugal force and the centripetal force according to the inclination of the bucket 140.

Rotation angle of the bucket 140 is in the range of 20 ~ 80 ° inclined angle can be adjusted around the center.

In addition, the configuration of the first other embodiment of the bucket is as follows.

As illustrated in FIG. 6, guide grooves 154 are further formed on both sides of the mounting holes 151 of the bucket 140 so that the support pieces 11b formed at the end of the syringe body 11 are inserted, so that the support pieces 11b of the syringe 10 are guide grooves 154. By allowing it to be mounted along, it is possible to reliably mount the syringe 10 in the bucket 140.

The configuration of the second alternative embodiment of the bucket is as follows.

As shown in FIG. 7, in order to satisfy compatibility with the bucket 140 according to the size of the syringe 10, the bucket 140 cuts a pair of the intervening grooves 155 downward from the upper end on the outer circumference thereof, and On the opposite side, the pinholes 156 are formed in a vertically downward direction to correspond to each other, and the locking pins 157 are coupled to the pinholes 156 of any one of the pinholes 156 to support the support piece 11b of the syringe 10. Include.

That is, in the case of the syringe 10 having a large capacity, the diameter of the syringe barrel 11 and the length of the flanger 12 are proportional to each other, and the upper and lower positions of the locking pin 157 are adjusted according to the size of the syringe 10.

Eventually, the support piece 11b of the syringe barrel 11 is seated by the catching pin 157 of the bucket 140, so that the syringe barrel 11 is stably stored in the bucket 140, and the flanger 12 is maintained under no pressure so that the inner space of the syringe This is to prevent the volume change.

In addition, an embodiment of the fixed centrifuge 100b is as follows.

First, as shown in FIG. 9, the fixed centrifuge 100 is formed with a circumference 121 of a rotor 120 interlocked with a rotating device 110 that receives a rotational force from a motor (not shown).

The mounting hole 151 and the receiving hole 152 are formed in multiple stages in the slope 121, and the syringe accommodating part 150 having a step 153 formed on the boundary between the mounting hole 151 and the receiving hole 152 is provided.

Then, the syringe 10 is coupled to the inside of the syringe accommodating part 150 to be disposed upward.

Wherein the syringe 10 is the lower end of the syringe barrel 11a is caught on the step 180, the flanger 12 is accommodated into the receiving hole 152.

This is the same principle as the angle-variable centrifuge, because the support piece 11b or the syringe barrel 11 of the syringe 10 is caught on the step 153, so that the centrifugal force acting on the syringe barrel 11 during the high-speed rotation of the centrifuge 100 causes the mounting hole 151 to be rearward. This is to prevent volume change by generating positive pressure between syringe 10 and spacer 12 while pushing.

As described above, the fixed centrifuge 100 is configured such that the tip of the syringe is disposed to be upwardly disposed so that the internal space of the syringe 100 can be centrifuged stably without a volume change when the centrifuge 100 rotates at a high speed.

This fixed centrifuge 100b has a stacked structure of the same adipocytes by the angle-variable centrifuge 100a.

In addition, as shown in Figure 10, another embodiment of the fixed centrifuge 100 is as follows.

A rotor 120 having a slope 121 is mounted around the fixed centrifuge 100 and detachably couples the syringe accommodating portion 150 having the same angle as the slope 121 into the rotor 120.

Here, the mounting hole 151, the receiving hole 152, and the step 153 of the syringe accommodating portion 150 have a half arc-shaped cross section and have a shape in which the front surface is opened.

In addition, a stepped 153 is formed at the inner circumference of the mounting groove 151, so that the support piece 11b of the syringe 10 is placed on the stepped 153 so that the syringe barrel 10 is stably installed without flow in the mounting hole 151.

Here, the tip of the syringe 10 is coupled to be disposed upward from the mounting hole to face the direction of rotation center of the rotating device 110.

The mounting groove 151 may further include a locking groove 158 formed on both sides of the mounting groove 151 such that the bent both ends of the clip 159 having elasticity may be fitted to hold the syringe barrel 11.

In another embodiment of the fixed centrifuge configured as described above, the syringe needle inlet 11a is placed upward while the syringe 10 is stably installed by the removable syringe receiver 150.

In addition, the clip 159 has its own elasticity, so that the clip 159 bends both ends of the clip 159 and then fits into the locking groove 158 so that the inner circumference of the clip 159 can grip the syringe barrel 11, thereby stably at high speed. Make sure that it stays in the mounting groove.

The present invention described above is not limited to the above-described embodiment and the accompanying drawings, and various substitutions, modifications, and changes are possible within the scope without departing from the technical spirit of the present invention. It will be evident to those who have the knowledge of.

1 is a perspective view showing a state in which the centrifuged adipocytes according to the prior art form an interlaminar structure in a test tube.

Figure 2 is a perspective view showing the interlayer structure inside the syringe centrifuged fat cells through the present invention.

Figure 3 is a perspective view of the angle-variable centrifuge of the centrifuge of the present invention.

Figure 4 is a perspective view of the bucket of the angle-variable centrifuge of the present invention.

Figure 5 is a cross-sectional view showing a bucket of the angle-variable centrifuge of the present invention.

Figure 6 is a perspective view showing a first alternative embodiment of the bucket of the angle-variable centrifuge of the present invention.

Figure 7 is a perspective view showing a second alternative embodiment of the bucket of the variable centrifuge of the present invention.

Figure 8 is a partially enlarged perspective view showing the mounting state of the bucket in the angle-variable centrifuge of the present invention.

Figure 9 is a perspective view of the fixed centrifuge of the centrifuge of the present invention.

10 is a perspective view showing another embodiment of the fixed centrifuge of the present invention.

11 is a sectional view showing a syringe mounted on another embodiment of the fixed centrifuge of the present invention.

Explanation of symbols on the main parts of the drawings

10: syringe 11: syringe body

11a: needle inlet 11b: backing piece

12: flanger 100: centrifuge

100a: variable angle centrifuge

100b: Fixed Centrifuge

110: rotating device 120: rotor

121: slope 130: clamp

131: fork 132: coupling hole

133: support pin 140: bucket

150: syringe housing 151: mounting hole

152: storage hole 153: step

154: guide groove 155: intervening groove

156: pin hole 157: locking pin

158: locking groove 159: clip

F: Pre-Oil E: Red Blood Cells

S: fat stem cell

Claims (8)

In the apparatus for centrifugation using a syringe for fat stem cell extraction, In the centrifuge to form a mounting hole for receiving the syringe barrel and a receiving hole for receiving the flanger in multiple stages, Steps are formed at the boundary between the mounting hole and the receiving hole so that the needle inlet of the syringe is mounted upward from the mounting hole, and the lower end of the syringe body is seated on the step, A centrifuge for centripetal mounting of a syringe tip, characterized in that the material having a lower specific gravity during centrifuge operation includes a syringe receptacle that can be positioned at the tip of the syringe. The method of claim 1, The centrifugal separator is provided with at least one clamp installed around the rotor interlocked with the rotating device, and a hinged coupling of the detachable bucket provided with a syringe receiving portion therein, the angle of the syringe tip characterized in that the variable angle Centrifuge for The method of claim 2, The clamp is formed of a pair of forks to sequentially form a coupling hole formed corresponding to the surface facing each other, and coupled to any one of the coupling holes across the support pin and hinged to the clamp Centrifuge for the centripetal mounting of the syringe tip, characterized in that configured so that the inclination angle of the bucket by limiting the outer circumference of the connected bucket. The method of claim 2, Centrifuge for centrifugal mounting of the syringe tip further comprises the guide grooves formed on both sides of the inner circumference of the mounting hole of the bucket so that the support piece is formed in the syringe barrel end. The method according to claim 2 or 4, The bucket cuts a pair of interposition grooves downwardly from the upper end on the outer periphery, and the pin holes are sequentially formed in a vertical downward direction to correspond to the facing surfaces of the interposition grooves in any one of the pin holes. Centrifuge for the centripetal mounting of the syringe tip, characterized in that it further comprises the engaging pin formed to support the backing of the syringe. The method of claim 3, The rotation angle of the bucket is a centrifuge for mounting the centrifugal direction of the syringe tip, characterized in that it is made to be inclined angle around the center in the range 20 ~ 80 °. The method of claim 1, Centrifuge for mounting the centrifugal direction of the tip of the syringe, characterized in that at least one syringe receiving portion having the same angle as the slope to the inside of the rotor to be applied to a fixed centrifuge equipped with a rotor with a slope formed around the centrifuge . The method of claim 1, Of the centrifuge has a semi-circular cross-section to apply to a centrifuge equipped with a rotor formed with a slope around the circumference and one side of the syringe receiving portion is coupled to the slope detachably, The center of the syringe tip further comprises forming a locking groove on both sides of the mounting hole having a half arc shape in the syringe receiving portion so that the bent both ends of the clip having elasticity can be fitted to grip the syringe body. Centrifuge for directional mounting.

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