KR100938817B1 - 안지오텐신 ⅱ 작용제로 유용한 삼중고리 화합물 - Google Patents

안지오텐신 ⅱ 작용제로 유용한 삼중고리 화합물 Download PDF

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Publication number
KR100938817B1
KR100938817B1 KR1020037015757A KR20037015757A KR100938817B1 KR 100938817 B1 KR100938817 B1 KR 100938817B1 KR 1020037015757 A KR1020037015757 A KR 1020037015757A KR 20037015757 A KR20037015757 A KR 20037015757A KR 100938817 B1 KR100938817 B1 KR 100938817B1
Authority
KR
South Korea
Prior art keywords
compound
formula
iso
butyl
sulfonamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020037015757A
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English (en)
Korean (ko)
Other versions
KR20040011519A (ko
Inventor
홀베르그안드레
메티아스 알터만
Original Assignee
바이코어 파마 아베
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0113129A external-priority patent/GB0113129D0/en
Priority claimed from GB0121611A external-priority patent/GB0121611D0/en
Priority claimed from GB0201794A external-priority patent/GB0201794D0/en
Application filed by 바이코어 파마 아베 filed Critical 바이코어 파마 아베
Priority claimed from PCT/GB2002/002563 external-priority patent/WO2002096883A1/en
Publication of KR20040011519A publication Critical patent/KR20040011519A/ko
Application granted granted Critical
Publication of KR100938817B1 publication Critical patent/KR100938817B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020037015757A 2001-05-31 2002-05-30 안지오텐신 ⅱ 작용제로 유용한 삼중고리 화합물 Expired - Fee Related KR100938817B1 (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GB0113129A GB0113129D0 (en) 2001-05-31 2001-05-31 Pharmaceutically-useful compounds
GB0113129.1 2001-05-31
GB0121611A GB0121611D0 (en) 2001-09-07 2001-09-07 Pharmaceutically-useful-compounds
GB0121611.8 2001-09-07
US35095902P 2002-01-25 2002-01-25
US60/350,959 2002-01-25
GB0201794.5 2002-01-26
GB0201794A GB0201794D0 (en) 2002-01-26 2002-01-26 Pharmaceutically-useful compounds
PCT/GB2002/002563 WO2002096883A1 (en) 2001-05-31 2002-05-30 Tricyclic compounds useful as angiotensin ii agonists

Publications (2)

Publication Number Publication Date
KR20040011519A KR20040011519A (ko) 2004-02-05
KR100938817B1 true KR100938817B1 (ko) 2010-01-26

Family

ID=32872450

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020037015757A Expired - Fee Related KR100938817B1 (ko) 2001-05-31 2002-05-30 안지오텐신 ⅱ 작용제로 유용한 삼중고리 화합물

Country Status (2)

Country Link
JP (1) JP4707321B2 (enrdf_load_stackoverflow)
KR (1) KR100938817B1 (enrdf_load_stackoverflow)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE540947T1 (de) * 2005-04-12 2012-01-15 Vicore Pharma Ab Neue tricyclische angiotensin-ii-agonisten
MX2009013971A (es) * 2007-06-20 2010-01-28 Mitsubishi Tanabe Pharma Corp Derivado de sulfonamida de acido malonico novedoso y su uso farmaceutico.
NZ712479A (en) * 2013-03-15 2019-01-25 Univ Southern California Methods, compounds, and compositions for the treatment of angiotensin-related diseases
WO2015152393A1 (ja) * 2014-04-03 2015-10-08 国立研究開発法人国立循環器病研究センター 悪性腫瘍転移抑制用医薬
GB201913603D0 (en) * 2019-09-20 2019-11-06 Vicore Pharma Ab New compounds
CN115605265A (zh) * 2020-03-19 2023-01-13 维科尔药物公司（Se） 用于治疗和/或预防与血管紧张素ii相关的疾病、病症或病状的新型化合物
GB202007122D0 (en) * 2020-05-14 2020-07-01 Vicore Pharma Ab New process
GB202013721D0 (en) * 2020-09-01 2020-10-14 Vicore Pharma Ab New compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000068226A1 (de) * 1999-05-05 2000-11-16 Aventis Pharma Deutschland Gmbh 1-(p-thienylbenzyl)-imidazole als agonisten von angiotensin-(1-7)-rezeptoren, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische präparate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198438A (en) * 1991-05-07 1993-03-30 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted thiophene or furan
US5444067A (en) * 1993-08-30 1995-08-22 Merck & Co., Inc. Pharmaceutical treatment methods using angiotensin II receptor agonists bearing a thiophene moiety

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000068226A1 (de) * 1999-05-05 2000-11-16 Aventis Pharma Deutschland Gmbh 1-(p-thienylbenzyl)-imidazole als agonisten von angiotensin-(1-7)-rezeptoren, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische präparate

Also Published As

Publication number Publication date
KR20040011519A (ko) 2004-02-05
JP4707321B2 (ja) 2011-06-22
JP2004533457A (ja) 2004-11-04

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