KR100920898B1 - Pore astringent cosmetic composition containing Poncirus trifoliate extract and hydrogenated phosphatidylcholine - Google Patents

Abstract

The present invention relates to a pore converging cosmetic composition containing a fruit juice extract and hydrated phosphatidylcholine (HPC). Fruits are dried tangerine fruit extracts that coagulate and contract proteins in the secretory glands of sebaceous glands and sweat glands, converging. HPC has the best sebum secretion function among phospholipid derivatives. Converging cosmetic composition containing the fruit extract and HPC according to the present invention can provide excellent converging cosmetics that can prevent pores expansion due to shrinking pores and excellent sebum secretion.

Fruit Extract, Phosphatidylcholine, Pore Convergence, Pore Reduction

Description

Pore astringent cosmetic composition containing Poncirus trifoliate extract and hydrogenated phosphatidylcholine

The present invention relates to a pore converging cosmetic composition containing fruit juice extract and HPC.

In general, cosmetics are aimed at the aesthetic function to clean human skin or express beautiful and attractive and the defense function to protect the skin from the harmful environment from the outside. This role of the skin declines due to various harmful environment (ultraviolet rays, increased radiation, air pollution, stress, irregular eating, etc.) cosmetics are caused by the reactive reactive oxygen, free radicals and peroxides caused by these harmful factors It not only improves the trouble of various skins, but also protects the skin and helps the skin to maintain its normal function.

One of the functions of maintaining healthy skin by skin protection of cosmetics is astringent action. Each person has various skin worries, but among them, the wide pores are considered to be the biggest enemy of the skin because the face looks dirty and the makeup is easily erased, and once widened, it is hard to get smaller. Accordingly, consumers' interest in pores is gradually increasing, and reducing the size of the pores is one of the important tasks to be solved by cosmetics pursuing the beauty of women.

The reason for the widening of pores is that the collagen fibers and elastic fibers supporting the pores wall degenerate and gradually decrease as the skin ages, and the elasticity of the skin disappears and the pores appear to be stretched, or excessive sebum secretion is the main cause. Normally our skin has oil glands called sebaceous glands, from which sebum is made and discharged through the pores. This sebum forms a fatty film on the skin and hair surface to protect our body from external germs, as well as to protect the skin from UV rays or moisturize the skin. If a disorder occurs in the process, the pores will enlarge.

The astringent effect of cosmetics refers to the contraction of excessively opened pores and pores, which makes the skin feel elastic and supple. Contraction of the skin has a physical and chemical action. The physical action is to temporarily lower the surface temperature of the skin by the heat of evaporation when the alcohol contained in the lotion evaporates, constricting the pores and the pores where sebum is secreted and converging effect, and the chemical action is the coagulation effect of acid or protein. Coagulates and contracts proteins in the secretory areas of sebaceous glands and sweat glands by a substance with astringent effect.

As a method for improving skin troubles related to pores, Korean Laid-Open Patent Publication No. 97-70601 discloses a method of contracting pores using astringents. However, by using astringents, temporary elasticity and pulling on the skin increases the pore size. It can not be solved fundamentally.

In addition, Japanese Patent Application Laid-Open No. 05-294836 discloses a method of inhibiting sebum secretion by reducing the amount of sebum secretion of sebaceous glands by taking oligosaccharides, but only by reducing the amount of sebum secretion in sebaceous glands It was not possible to eliminate the roughness of the skin.

Thus, the present inventors have been added to the fruit extract and HPC in the cosmetics to solve the above problems, not only excellent sebum secretion function and pore contraction function, but also prevents skin problems and develops a non-toxic cosmetic composition will be.

Accordingly, it is an object of the present invention to provide a cosmetic composition for pore convergence containing fruit juice extract and HPC.

The present invention relates to a pore converging cosmetic composition containing a fruit juice extract and hydrated phosphatidylcholine (HPC). Converging cosmetic composition containing the fruit extract and HPC according to the present invention can provide excellent converging cosmetics that can prevent pores expansion due to shrinking pores and excellent sebum secretion.

The present invention relates to an excellent pore-converging cosmetic composition having excellent pore contraction function and suppression of pore expansion through sebum secretion by adding HPC, a phospholipid (Phospholipid) derivative having the most excellent sebum suppression function, to the cosmetics. will be.

The fruit fruit used in the fruit fruit extract of the present invention is the unripe fruit of the tanza tree, which is a evergreen evergreen plant with the incense family. Being mature is called perception.

Poncirus trifoliate grows 3-4 m high, flowers bloom in white 1-2 at the end of the stem or on the axillary leaves before the leaves in May. Fruits are berry, round and blue, and yellow when ripe. Fruits ripen in September with good fragrance but not eaten. In oriental medicine, the fruit is used as a medicine to stop the stomach, digestion, abdominal pain, and coronary heart disease is used in combination with baekbaek, fruit juice and painful symptoms.

In the present specification, the term "pile fruit extract" means obtained by extracting from dried fruit room, raw fruit room, cooked fruit room, frozen fruit room, etc., preferably means dried fruit room.

The fruit extract of the present invention comprises (a) water, (b) anhydrous or hydrous lower alcohol having 1 to 4 carbon atoms (such as methanol, ethanol, propanol and butanol), (c) acetone, (d) ethyl acetate, (e) A solvent selected from the group consisting of chloroform, (f) butyl acetate and (g) 1,3-butylene glycol was obtained from the basement as an extraction solvent. The extraction solvent is preferably a hydrous lower alcohol, more preferably 50-90% alcohol, most preferably 70% alcohol. A suitable amount of the extraction solvent is 1-20 times the dry weight of the fruiting chamber, more preferably 1-10 times.

According to a preferred embodiment of the present invention, the method for preparing the fruit extract of the present invention is as follows. The fruit extract of the present invention is dried fruit of wild or cultivated tanza, washed with clean water, dried and finely powdered, and 70% ethyl as an extract solvent of 6 times the dry weight of the powdered fruit powder. Extract with alcohol [ethyl alcohol 70: water 30 (v / v)]. Next, using a distillation apparatus equipped with a cooling capacitor, while recovering the solvent evaporated, it is concentrated under reduced pressure to obtain the desired fruit extract of the present invention.

On the other hand, it will be apparent to those skilled in the art that the extract of the present invention can be obtained as well as the above-described extraction solvent, as well as fruity extracts having substantially the same effect using other extraction solvents.

In addition, the extract of the present invention includes not only the extract by the above-described extraction solvent, but also the extract that has undergone a conventional purification process. Obtained by various additional purification methods, such as, for example, separation using an ultrafiltration membrane having a constant molecular weight cut-off value, separation by various chromatography (manufactured for separation according to size, charge, hydrophobicity or affinity). The fraction is also included in the fruiting extract of the present invention.

The fruit extract of the present invention may be prepared in powder form by an additional process such as distillation under reduced pressure and freeze drying or spray drying.

The HPC of the present invention is a Phospholipid derivative and other derivatives such as phosphatidylcholine (hereinafter referred to as PC), phosphatidylserine (hereinafter referred to as PS), and hydrated phosphatidylserin (hereinafter referred to as HPS). Compared to sebum secretion ability is excellent raw material. Phospholipids make up the cell membrane and play a very important role in neurotransmission and maintenance of the cell membrane.

HPC of the present invention was purchased from Doosan Biotech Co., Ltd. (Korea).

According to a preferred embodiment of the present invention, the content of the fruit extract in the composition of the present invention is 0.0001 to 20% by weight, preferably 0.001 to 10% by weight relative to the total weight of the composition, the content of the HPC is the total weight of the composition It is 0.01-10% by weight, preferably 0.1-5.0% by weight. In the cosmetic composition of the present invention, when the content of the active ingredient is less than the minimum content, there is a problem in that a pore convergence effect cannot be expected. If the maximum content is exceeded, there is no increase in the apparent effect with the increase of the content and there is a problem in the stability of the formulation.

Throughout this specification, "convergence" refers to the action of shrinking the pores of the skin, and refers to making the skin feel elasticity and suppleness through shrinking pores.

The cosmetic composition of the present invention may include other skin astringent components (pores shrinkage components) in addition to the fruit compartment extract and HPC as an active ingredient. However, the cosmetic composition of the present invention shows a very good skin astringent effect even with the active ingredient consisting only of the fruit fruit extract and HPC.

Converging cosmetics containing the fruit extract and HPC of the present invention is a convergent cosmetic (skin), a convergent cosmetic (aftershave skin), astringent / nourishing cosmetics (lotion), astringent / nourishing cosmetics (aftershave lotion), a convergent cream, a convergent cream (Perspiration cream) or a convergence pack or the like.

Ingredients included in the cosmetic composition of the present invention as an active ingredient includes components commonly used in cosmetic compositions in addition to the active ingredient, for example, conventional auxiliaries such as antioxidants, stabilizers, solubilizers, vitamins, pigments and flavors, And carriers.

The cosmetic composition of the present invention may be prepared in any formulation commonly prepared in the art, for example, solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, surfactant-containing cleansing , Oils, powder foundations, emulsion foundations, wax foundations and sprays, and the like, but are not limited thereto. More specifically, astringent makeup (skin), astringent makeup (aftershave skin), astringent / nutrition makeup (lotion), astringent / nutrition makeup (after shave lotion), a convergence cream, a convergence cream (perspiration cream) or a convergence pack, etc. It can be prepared in the formulation of.

When the formulation of the present invention is a paste, cream or gel, animal oils, vegetable oils, waxes, paraffins, starches, trachants, cellulose derivatives, polyethylene glycols, silicones, bentonites, silicas, talc or zinc oxide may be used as carrier components. Can be.

When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used, in particular in the case of a spray, additionally chlorofluorohydrocarbon, propane Propellant such as butane or dimethyl ether.

When the formulation of the present invention is a solution or emulsion, a solvent, solubilizer or emulsifier is used as the carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1 Fatty acid esters of, 3-butylglycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan.

When the formulation of the present invention is a suspension, liquid carrier diluents such as water, ethanol or propylene glycol, suspending agents such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol esters and polyoxyethylene sorbitan esters, and microcrystals are used as carrier components. Soluble cellulose, aluminum metahydroxy, bentonite, agar or tracant and the like can be used.

When the formulation of the present invention is a surfactant-containing cleansing, the carrier component is aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcosinate, fatty acid amide. Ether sulfates, alkylamidobetaines, aliphatic alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, lanolin derivatives or ethoxylated glycerol fatty acid esters and the like can be used.

The cosmetic composition of the present invention exhibits excellent pore astringent effect by agglomerating protein of skin pores and shrinking skin pores by including the fruit extract and HPC as an active ingredient. In addition, even if it contains the fruit extract does not cause any skin irritation is excellent skin safety.

Hereinafter, the present invention will be described in more detail with reference to Examples. These examples are only for illustrating the present invention in more detail, it will be apparent to those skilled in the art that the scope of the present invention is not limited by these examples in accordance with the gist of the present invention. .

Production Example  1. Fruit Extract Extract

100 g of dried citric acid was added to 600 g of a mixed solution of water / ethanol (3/7, v / v), extracted at room temperature for 5 days, and filtered using Whatman filter paper (No. 5). Put in an extractor equipped and concentrated under reduced pressure at 70 ℃ to obtain a powder 5.6 g. The extracted powder is then added to a 50% 1,3 butylene glycol solution so that the final concentration of the fat chamber powder is 1% (w / v).

Experimental Example 1. Protein aggregation effect of fruit extract

Protein aggregation effect was measured for the fruit extract prepared from Preparation Example 1.

In the protein aggregation effect test, 1 ml of fruit juice extract was added to 2 mL of 50 mM citric acid buffer solution (pH 4.5) containing 0.3% albumin as a protein, shaken well, stopped for 5 minutes, and the turbidity was measured at 650 nm. At this time, the fruit extract was prepared by using the one prepared in Preparation Example 1 was dissolved in a constant concentration (0.1, 0.5, 1.0, 2.0, 5.0%) in the buffer solution was added, the results are shown in Table 1 below.

Converging Effect of Fruit Extracts (Protein Aggregation Effect) Fruit Fruit Extract (%) Absorbance (650 nm) 0.0 0.453 0.1 0.460 0.5 0.721 1.0 0.930 2.0 1.120 5.0 1.450

In this experiment, the higher the absorbance value, the higher the protein aggregation effect, and the better the protein aggregation effect, the better the convergence effect. Therefore, as can be seen in the results of Table 1, the higher the content of the fruit extract was confirmed that the aggregation effect also increased.

Experimental Example 2 Pore Converging Effect of Fruit Extracts

The convergence effect of the fruit extract prepared in Preparation Example 1 was measured by the following method.

This experimental method was also evaluated using the precipitation reaction in the same manner as in Experimental Example 1, in which the precipitation reaction was performed using Bovine hemoglobin (Sigma, United States) protein. First, prepare a 1 mg-hemoglobin / ml phosphate buffered saline (pH 6.8) solution, and dilute the solution and the fruit extracts in buffer solution by concentration, mix the two solutions 1: 1, and leave for 30 minutes. The amount of hemoglobin remaining was determined by measuring the absorbance at 407 nm. At this time, the concentration of the fruit extract was adjusted to 0.1, 0.5, 1.0, 2.0, 5.0% was used, the cosmetic containing no fruit extract was used as a control. The convergence effect was calculated according to Equation 1 below, and the results are shown in Table 2 below.

Converging Effect of Fruit Extract (Pore Contraction) Fruit juice extract concentration (%) Absorbance (650 nm) 0.1 13.2 0.5 23.5 1.0 46.3 2.0 63.5 5.0 72.3

As can be seen from the results in Table 2, the fruit extract of the present invention was confirmed that the pore shrinkage effect increases in a concentration-dependent manner, the effect is also high.

Experimental Example 3. Experiment to measure sebum secretion inhibitory effect of HPC

A 20-50 year old female group was tested to measure sebum secretion effect of HPC in 20 owners of oily skin. Experiment HPC on the left side of the forehead and the control without HPC on the right side of the forehead were applied twice a day in the morning and evening and after 1 week, 2 weeks, 3 weeks and 4 weeks Sebum secretion of the skin was measured using (Sebum meter SM 810). The experiment was carried out at 20 ℃ and 20% relative humidity. For oily skin, the measured value is over 220 ug / cm2 and for normal skin, it is 100 ~ 220 ug / cm2. The experimental results are shown in Table 3 below.

Determination of sebum secretion effect of HPC Initial (0 weeks) 1 week 2 weeks 3 weeks 4 Weeks HPC 250 220 202 190 182 Control 250 233 230 228 226

As can be seen from the results of Table 3, HPC was confirmed that the sebum secretion inhibitory effect is superior to the control group.

Formulation Example 1. Soft Cosmetics

Prescription examples of the flexible cosmetic water in cosmetics containing fruit fruit extract and HPC are as follows.

Fruit Extract Extract HPC Glycerin 1.3-Butylene Glycol Fiji 1500 Allantoin DL-Pantenol E.D.T.A-2NA Benzophenone-9 Sodium Hyaluronate Ethanol Octicdodeceth-16 Polysorbate 20 Preservative, Flavor, Pigment Distilled Water 2.0 1.0 5.0 3.0 1.0 0.1 0.3 0.02 0.04 5.0 10.0 0.2 0.2 Sum 100

Prescription example 2. Convergence lotion

A prescription example of astringent lotion among cosmetics containing fruit juice extract and HPC is as follows.

Ingredients (content: weight%) Comparative Example 1 Example 1 Comparative Example 1 Comparative Example 2 Fruits Extract HPC Glycerin 1.3-Butylene Glycol Allantoin DL-Pantenol E.D.T.-2-2 Benzophenone-9 Sodium Hyaluronate Ethanol Polysorbate 20 Witch Hazel Extract Citric Acid Preservative, Flavor, Dye Water --2.0 2.0 0.2 0.2 0.02 0.04 3.0 15.0 0.3 2.0 Trace Trace Amount 2.0 1.0 2.0 2.0 0.2 0.2 0.02 0.04 3.0 15.0 0.3 2.0 2.0-2.0 2.0 0.2 0.2 0.02 0.04 3.0 15.0 0.3 2.0 -1.0 2.0 2.0 0.2 0.2 0.02 0.04 3.0 15.0 0.3 2.0 Sum 100 100 100 100

Prescription Example 3. Nutritional Cosmetics

Prescription examples of nutrient cosmetics in cosmetics containing fruit extract and HPC are as follows.

ingredient Content (unit: weight%) Fruits Extract HPC Glyceryl Stearate SE Stearyl Alcohol Lanolin Polysorbate 60 Solbitan Stearate Cured Vegetable Oil Mineral Oil Squalane Trioctanoin Dimethicone Tocopherol Acetate Carboxyvinyl Polymer Glycerin 1.3-Butylene Glycol Sodium Hyaluronate Tri Ethanolamine Preservative Pigment distilled water 2.0 1.0 1.5 1.5 1.5 1.3 0.5 1.0 5.0 3.0 2.0 0.8 0.5 0.12 5.0 3.0 5.0 0.12 Sum 100

Prescription 4. Nutritional Cream

Prescription examples of nutritional cream in cosmetics containing fruit fruit extract and HPC are as follows.

ingredient Content (unit: weight%) Fruit oil extract HPC lipophilic monostearate glycerine cetearyl alcohol stearic acid wax polysorbate 60 sorbitan stearate hardened vegetable oil squalane mineral oil trioctanoin dimethicone sodium magnesium silicate glycerin betaine triethanolamine sodium hyaluronate preservative Distilled water 2.0 1.0 2.0 2.2 1.5 1.0 1.5 0.6 1.0 3.0 5.0 5.0 1.0 0.1 5.0 3.0 1.0 4.0 Sum 100

Prescription example 5. Massage cream

A prescription example of a massage cream in cosmetics containing fruit juice extract and HPC is as follows.

ingredient Content (unit: weight%) Fruit Extract Extract HPC Lipophilic Monostearic Acid Glycerin Stearyl Alcohol Stearic Acid Polysorbate 60 Sorbitastearate Isostearyl Isorate Squalane Mineral Oil Dimethicone Hydroxyethyl Cellulose Glycerine Triethanolamine Preservative, Flavor, Pigment Distilled Water 2.0 1.0 1.5 1.5 1.0 1.5 0.6 5.0 5.0 35.0 0.5 0.12 6.0 0.7 Microbalance Sum 100

Experimental Example 4. Pore shrinkage effect experiment of cosmetics containing fruit extract and HPC

The pores shrinkage effect of the cosmetic of the present invention was evaluated through a practical test. The pore contraction effect was prepared in Formulation Example 2 Example 1 (cosmetic extract 2% and HPC 1% cosmetics), Comparative Example 1 (prescription only 2 HPC 1% convergence cosmetic), Comparative Example 2 (prescription In Example 2, astringent cosmetic except 2% of the fruit fruit extract, and Comparative Example 1 (cosmetic extract containing neither the fruit fruit extract nor HPC in the prescription example 2) was carried out. The test subjects were 20 to 50 years old females with 60 oily skin owners randomly divided into three groups to use the products of Comparative Example 1, Example 1, Comparative Example 1 and Comparative Example 2. How to use: After a certain period of time after washing, apply the product of Examples and Comparative Examples to the left part of the face, and the product of the Comparative Example to the right part of the face twice a day, morning and evening, and then use the pores 4 weeks later. Was measured visually. The experimental results are shown in Table 9 below.

Pore shrinkage effect (visual evaluation) Excellent pores shrinkage effect Pore shrinkage effect slightly no effect Effectiveness (%) Comparative example 2 2 56 20.0 Example 1 15 4 One 95.0 Comparative Example 1 (excluding HPC) 9 6 5 75.0 Comparative Example 2 (except fruit extract) 6 6 8 60.0

As can be seen from the results of Table 8, the cosmetics of the present invention (Example 1) containing the fruit fruit extract and HPC shows a higher pore shrinkage effect than the cosmetics of the comparative examples containing only fruit fruit extract or HPC alone In particular, the pore contraction effect was superior to the comparative example used as a control. Moreover, skin irritation could not be observed in the subjects of the part which apply | coated the cosmetic of this invention to skin.

Having described the specific part of the present invention in detail, it is apparent to those skilled in the art that the specific technology is merely a preferred embodiment, and the scope of the present invention is not limited thereto. Thus, the substantial scope of the present invention will be defined by the appended claims and equivalents thereof.

Claims (5)

A cosmetic composition for converging pores containing fruit juice extract and HPC (hydrogenated phosphatidylcholine) as an active ingredient. According to claim 1, wherein the fruit extract extract pore shrinkage effect by the protein coagulation of the pores, HPC has a sebaceous gland secretion, characterized in that the cosmetic composition for pore convergence. The method of claim 1, wherein the fruit extract contains 0.0001-20.0% (v / v) to the total weight of the cosmetic composition, the HPC contains 0.01-10% of the total weight of the cosmetic composition. Cosmetic composition for. According to claim 1, wherein the cosmetic composition for converging pores convergence (skin), convergence longevity (aftershave skin), convergence / nutritional makeup (lotion), convergence / nutritional makeup (aftershave lotion), convergence cream, convergence cream (Perspiration cream) and a cosmetic composition for pore convergence, characterized in that the formulation is selected from the group consisting of a convergence pack. A cosmetic method for shrinking pores of the skin comprising applying the cosmetic composition of claim 1 to human skin.