KR100900648B1 - 랑게르한스 세포 이동을 억제하기 위한 적어도 1개의옥사졸린을 포함하는 조성물, 및 이의 용도 - Google Patents
랑게르한스 세포 이동을 억제하기 위한 적어도 1개의옥사졸린을 포함하는 조성물, 및 이의 용도 Download PDFInfo
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- KR100900648B1 KR100900648B1 KR1020047010261A KR20047010261A KR100900648B1 KR 100900648 B1 KR100900648 B1 KR 100900648B1 KR 1020047010261 A KR1020047010261 A KR 1020047010261A KR 20047010261 A KR20047010261 A KR 20047010261A KR 100900648 B1 KR100900648 B1 KR 100900648B1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/51—Chelating agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Immunology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Cosmetics (AREA)
Abstract
Description
Claims (21)
- 삭제
- 삭제
- - 피부 또는 점막의 알레르기성 또는 염증성 또는 자극성 반응;- 민감성 또는 반응성 또는 불쾌한 또는 내성이 약한 피부 또는 점막, 또는 내인성 노화, 외인성 노화 또는 호르몬성 노화와 관련된 면역학적 불균형을 나타내거나 또는 배리어 장애를 보이는 피부 또는 점막;- 아토피성 습진(atopic eczema) 또는 접촉 습진, 염증성 피부염, 자극성 피부염, 자가 면역 질환, 광-면역-억제 또는 이식편 거부(graft rejection);로 이루어진 그룹으로부터 선택되는 증상 또는 질환을 치료하기 위한 약학 조성물로서,2-운데실-4-히드록시메틸-4-메틸-1,3-옥사졸린,2-운데실-4,4-디메틸-1,3-옥사졸린,(E)-4,4-디메틸-2-헵타덱-8-엔일-1,3-옥사졸린,4-히드록시메틸-4-메틸-2-헵타데실-1,3-옥사졸린,(E)-4-히드록시메틸-4-메틸-2-헵타덱-8-엔일-1,3-옥사졸린, 및2-운데실-4-에틸-4-히드록시메틸-1,3-옥사졸린,으로 이루어지는 그룹으로부터 선택되는 적어도 하나의 옥사졸린을 포함하고,랑게르한스 세포의 이동을 억제하는 것을 특징으로 하는 약학 조성물.
- 청구항 3에 있어서, 루핀의 펩티드 추출물 및 레티노이드(retinoids)로 이루어지는 그룹으로부터 선택되는 적어도 하나의 메탈로프로테아제(MMPs) 억제제, 또는 알칸올아미드로부터 선택되는 적어도 하나의 화합물을 더욱 포함하는 것을 특징으로 하는 약학 조성물.
- 청구항 4에 있어서, 상기 메탈로프로테아제(MMPs) 억제제는 루핀의 펩티드 추출물로 이루어지는 그룹 중에서 선택되는 것을 특징으로 하는 약학 조성물.
- 청구항 4에 있어서, 상기 메탈로프로테아제 억제제는 레티노이드로 이루어지는 그룹 중에서 선택되는 것을 특징으로 하는 약학 조성물.
- 청구항 3 내지 청구항 7 중 어느 한 항에 있어서, 상기 옥사졸린의 농도가 약학 조성물의 전체 중량에 비해 0.001 내지 10중량% 인 것을 특징으로 하는 약학 조성물.
- 삭제
- 삭제
- 삭제
- 삭제
- 삭제
- 삭제
- 삭제
- 청구항 3에 있어서, 상기 염증성 피부염은 건선(psoriasis)인 것을 특징으로 하는 약학 조성물.
- 삭제
- 삭제
- 위험 신호가 가해지면 피부 발진과 함께 피부 배리어 장애를 나타내거나, 내인성 노화, 외인성 노화 또는 호르몬성 노화와 관련된 비-병리학적 면역 불균형을 나타내는 민감성, 자극성, 내성이 약한 또는 알레르기 빈발성 피부 또는 점막에 처치하기 위한 미용 조성물로서,- 2-운데실-4-히드록시메틸-4-메틸-1,3-옥사졸린, 2-운데실-4,4-디메틸-1,3-옥사졸린, (E)-4,4-디메틸-2-헵타덱-8-엔일-1,3-옥사졸린, 4-히드록시메틸-4-메틸-2-헵타데실-1,3-옥사졸린, (E)-4-히드록시메틸-4-메틸-2-헵타덱-8-엔일-1,3-옥사졸린, 및 2-운데실-4-에틸-4-히드록시메틸-1,3-옥사졸린으로 이루어지는 그룹으로부터 선택되는 적어도 하나의 옥사졸린; 및- 루핀의 펩티드 추출물 및 레티노이드(retinoids)로 이루어지는 그룹으로부터 선택되는 적어도 하나의 메탈로프로테아제 억제제, 또는 알칸올아미드으로부터 선택되는 적어도 하나의 화합물;을 포함하고,랑게르한스 세포의 이동을 억제하는 것을 특징으로 하는 미용 조성물.
- 삭제
- 청구항 19에 있어서, 상기 옥사졸린의 농도가 상기 미용 조성물의 전체 중량에 비해 0.001 내지 10중량% 인 것을 특징으로 하는 미용 조성물.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR01/16917 | 2001-12-27 | ||
FR0116917A FR2834216B1 (fr) | 2001-12-27 | 2001-12-27 | Composition cosmetique ou pharmaceutique comprenant au moins une oxazoline pour inhiber la migration des cellules de langerhans, et ses utilisations |
PCT/FR2002/004583 WO2003055463A1 (fr) | 2001-12-27 | 2002-12-27 | Composition comprenant au moins une oxazoline pour inhiber la migration des cellules de langerhans, et ses utilisations |
Publications (2)
Publication Number | Publication Date |
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KR20040095201A KR20040095201A (ko) | 2004-11-12 |
KR100900648B1 true KR100900648B1 (ko) | 2009-06-02 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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KR1020047010261A KR100900648B1 (ko) | 2001-12-27 | 2002-12-27 | 랑게르한스 세포 이동을 억제하기 위한 적어도 1개의옥사졸린을 포함하는 조성물, 및 이의 용도 |
Country Status (12)
Country | Link |
---|---|
US (2) | US8236836B2 (ko) |
EP (1) | EP1458349B1 (ko) |
JP (1) | JP4767497B2 (ko) |
KR (1) | KR100900648B1 (ko) |
CN (1) | CN1617704B (ko) |
AU (1) | AU2002365026A1 (ko) |
CA (1) | CA2472190C (ko) |
ES (1) | ES2528675T3 (ko) |
FR (1) | FR2834216B1 (ko) |
HK (1) | HK1068105A1 (ko) |
MX (1) | MXPA04006418A (ko) |
WO (1) | WO2003055463A1 (ko) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5674477A (en) * | 1995-02-28 | 1997-10-07 | Ahluwalia; Gurpreet S. | Reduction of hair growth |
FR2847473B1 (fr) | 2002-11-25 | 2007-06-29 | Expanscience Lab | Composition comprenant au moins une oxazolidinone, son utilisation cosmetique et comme medicament |
FR2856294B1 (fr) | 2003-06-18 | 2005-08-05 | Expanscience Lab | Utilisation cosmetique d'une composition comprenant au moins une oxazoline, a titre de principe actif, comme amincissant et/ou pour prevenir et/ou traiter la cellulite |
JP2006206538A (ja) * | 2005-01-31 | 2006-08-10 | Institute Of Physical & Chemical Research | 抗原提示細胞の機能制御剤 |
FR2885128B1 (fr) * | 2005-04-27 | 2007-07-06 | Expanscience Laboratoires Sa | Composition cosmetique a visee depigmentante ou eclaircissante comprenant au moins une oxazoline, a titre de principe actif depigmentant ou eclaircissant |
KR20080055852A (ko) * | 2005-08-31 | 2008-06-19 | 세렌티스 리미티드 | 스타필로코커스 아우레우스에 의한 콜로니화를 특징으로하는 염증성 피부 병태의 치료를 위한 아우레오리신억제제의 용도 |
FR2908650B1 (fr) * | 2006-11-16 | 2012-05-25 | Lvmh Rech | Utilisation d'une alkyloxazolidinone comme agent cosmetique hydratant et procede d'hydratation de la peau. |
FR2953722B1 (fr) | 2009-12-16 | 2012-03-09 | Expanscience Lab | Composition comprenant au moins un sucre en c7 pour le traitement de l'alopecie, pour le traitement cosmetique des phaneres, et pour le soin des cheveux, cils ou ongles |
CN104244948B (zh) * | 2012-02-17 | 2016-11-16 | 爱普泰克集团有限公司 | 在炎症性疾病的治疗中使用的用于调节n-酰基乙醇胺的特异性酰胺酶的组合物和方法 |
FR3068045B1 (fr) | 2017-06-22 | 2021-06-04 | Expanscience Lab | Modeles de peau sensible reconstituee |
CN108250162B (zh) * | 2017-12-27 | 2021-06-22 | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | 一种医药中间体二芳基环氧乙烷化合物及其合成方法 |
FR3098394B1 (fr) * | 2019-07-12 | 2022-07-08 | Expanscience Lab | Composition comprenant au moins une oxazoline pour inhiber la croissance de levure du genre Malassezia impliquée notamment dans les croûtes de lait |
Citations (2)
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US4876249A (en) * | 1987-01-12 | 1989-10-24 | Rajadhyaksha Vithal J | Compositions and method comprising heterocyclic compounds containing two heteroatoms |
US5360811A (en) | 1990-03-13 | 1994-11-01 | Hoechst-Roussel Pharmaceuticals Incorporated | 1-alkyl-, 1-alkenyl-, and 1-alkynylaryl-2-amino-1,3-propanediols and related compounds as anti-inflammatory agents |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
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US2368075A (en) * | 1943-09-11 | 1945-01-23 | Commercial Solvents Corp | Astringent preparations |
US4345084A (en) * | 1981-06-29 | 1982-08-17 | Hoffmann-La Roche Inc. | Unsaturated eicosanoic acids |
WO1996016635A1 (en) * | 1994-11-28 | 1996-06-06 | Gist-Brocades B.V. | Topical application of ceramides |
US5955092A (en) * | 1996-09-27 | 1999-09-21 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing an n-substituted fatty acid amide and retinol or retinyl ester |
JPH1121247A (ja) * | 1997-06-30 | 1999-01-26 | Lion Corp | 皮膚賦活剤及びアレルギー抑制剤 |
EP0908179A1 (en) * | 1997-08-23 | 1999-04-14 | Werner Bollag | Treatment of cell-mediated immune diseases |
WO1999029293A1 (en) * | 1997-12-05 | 1999-06-17 | Dsm N.V. | Compositions comprising a combination of a free sphingoid base and a ceramide and uses thereof |
EP1059085A1 (en) * | 1998-02-26 | 2000-12-13 | Chugai Seiyaku Kabushiki Kaisha | Langerhans cell migration inhibitors |
FR2792202B1 (fr) * | 1999-04-19 | 2003-06-13 | Pharmascience Lab | Extrait peptidique de lupin et composition pharmaceutique ou cosmetique ou nutraceutique comprenant un tel extrait |
JP2001064192A (ja) * | 1999-08-25 | 2001-03-13 | Sunstar Inc | ランゲルハンス細胞の遊走抑制剤及び抗原提示抑制剤 |
CN1642973A (zh) * | 2000-09-06 | 2005-07-20 | 奥索-麦克尼尔药品公司 | 治疗变态反应的方法 |
EP1411930B1 (en) * | 2001-06-08 | 2013-01-16 | Cytokine Pharmasciences, Inc. | Isoxazoline compounds having mif antagonist activity |
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2001
- 2001-12-27 FR FR0116917A patent/FR2834216B1/fr not_active Expired - Lifetime
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2002
- 2002-12-27 JP JP2003556041A patent/JP4767497B2/ja not_active Expired - Lifetime
- 2002-12-27 AU AU2002365026A patent/AU2002365026A1/en not_active Abandoned
- 2002-12-27 US US10/499,976 patent/US8236836B2/en active Active
- 2002-12-27 KR KR1020047010261A patent/KR100900648B1/ko active IP Right Grant
- 2002-12-27 CN CN028276922A patent/CN1617704B/zh not_active Expired - Lifetime
- 2002-12-27 CA CA2472190A patent/CA2472190C/fr not_active Expired - Lifetime
- 2002-12-27 EP EP02805813.9A patent/EP1458349B1/fr not_active Expired - Lifetime
- 2002-12-27 MX MXPA04006418A patent/MXPA04006418A/es active IP Right Grant
- 2002-12-27 ES ES02805813.9T patent/ES2528675T3/es not_active Expired - Lifetime
- 2002-12-27 WO PCT/FR2002/004583 patent/WO2003055463A1/fr active Application Filing
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2005
- 2005-03-01 HK HK05101747.9A patent/HK1068105A1/xx not_active IP Right Cessation
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2009
- 2009-01-13 US US12/352,973 patent/US8653117B2/en not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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US4876249A (en) * | 1987-01-12 | 1989-10-24 | Rajadhyaksha Vithal J | Compositions and method comprising heterocyclic compounds containing two heteroatoms |
US5360811A (en) | 1990-03-13 | 1994-11-01 | Hoechst-Roussel Pharmaceuticals Incorporated | 1-alkyl-, 1-alkenyl-, and 1-alkynylaryl-2-amino-1,3-propanediols and related compounds as anti-inflammatory agents |
Also Published As
Publication number | Publication date |
---|---|
US20090137453A1 (en) | 2009-05-28 |
US20050075380A1 (en) | 2005-04-07 |
CN1617704B (zh) | 2011-10-05 |
EP1458349B1 (fr) | 2014-11-05 |
WO2003055463A1 (fr) | 2003-07-10 |
FR2834216A1 (fr) | 2003-07-04 |
US8236836B2 (en) | 2012-08-07 |
HK1068105A1 (en) | 2005-04-22 |
EP1458349A1 (fr) | 2004-09-22 |
CN1617704A (zh) | 2005-05-18 |
ES2528675T3 (es) | 2015-02-11 |
CA2472190A1 (fr) | 2003-07-10 |
FR2834216B1 (fr) | 2004-04-30 |
AU2002365026A1 (en) | 2003-07-15 |
JP2005517671A (ja) | 2005-06-16 |
MXPA04006418A (es) | 2004-11-10 |
CA2472190C (fr) | 2012-04-24 |
KR20040095201A (ko) | 2004-11-12 |
JP4767497B2 (ja) | 2011-09-07 |
US8653117B2 (en) | 2014-02-18 |
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