KR100898509B1 - 단삼 추출물을 포함하는 혈전 형성 예방용 기능성 식품 및 약학 조성물 - Google Patents
단삼 추출물을 포함하는 혈전 형성 예방용 기능성 식품 및 약학 조성물 Download PDFInfo
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- KR100898509B1 KR100898509B1 KR1020070059264A KR20070059264A KR100898509B1 KR 100898509 B1 KR100898509 B1 KR 100898509B1 KR 1020070059264 A KR1020070059264 A KR 1020070059264A KR 20070059264 A KR20070059264 A KR 20070059264A KR 100898509 B1 KR100898509 B1 KR 100898509B1
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- KR
- South Korea
- Prior art keywords
- extract
- acid
- salvia
- ethyl acetate
- salvianolic acid
- Prior art date
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- SNKFFCBZYFGCQN-UHFFFAOYSA-N 2-[3-[3-[1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]carbonyl-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-4-yl]prop-2-enoyloxy]-3-(3,4-dihydroxyphenyl)propanoic acid Chemical compound C=1C=C(O)C=2OC(C=3C=C(O)C(O)=CC=3)C(C(=O)OC(CC=3C=C(O)C(O)=CC=3)C(O)=O)C=2C=1C=CC(=O)OC(C(=O)O)CC1=CC=C(O)C(O)=C1 SNKFFCBZYFGCQN-UHFFFAOYSA-N 0.000 claims abstract description 45
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Abstract
Description
시료 | Total polyphenols (mg/g) | Total flavonoids (mg/g) | |
실시예1 | MeOH extract | 84.53±4.47 | 3.96±0.34 |
실시예2 | Hexane fraction | 54.25±3.61 | 37.38±1.31 |
실시예3 | Chloroform fraction | 54.72±7.6 | 13.96±0.8 |
실시예4 | Ethyl acetate fraction | 578.33±42.7 | 29.36±1.29 |
실시예5 | Butanol fraction | 251.34±11.12 | 5.24±1.08 |
실시예6 | Water fraction | 60.93±7.67 | 1.29±0.14 |
Time (min) | Buffer A (%) | Buffer B (%) |
0 | 100 | 0 |
12 | 88 | 12 |
20 | 80 | 20 |
30 | 70 | 30 |
31 | 100 | 0 |
40 | 100 | 0 |
Claims (10)
- 삭제
- 단삼의 알코올 추출물을 에틸아세테이트로 추출하여 분획한 에틸아세테이트 분획물인 단삼(Salvia miltiorrhiza Bunge) 추출물과, 식품학적으로 허용 가능한 식품보조첨가제를 함유하며, 상기 단삼 추출물은 살비아놀산 B(salvianolic acid B)와 로즈마린산(rosmarinic acid)을 50~70 : 10~30 중량비로 포함하는 혈전 형성 예방용 기능성 식품.
- 삭제
- 제 2 항에 있어서,정제, 과립제, 연질캅셀제, 액제 제형, 음료 및 다류 중 선택된 것임을 특징으로 하는 기능성 식품.
- 삭제
- 단삼의 알코올 추출물을 에틸아세테이트로 추출하여 분획한 에틸아세테이트 분획물인 단삼(Salvia miltiorrhiza Bunge) 추출물을 유효성분으로 함유하며, 상기 단삼 추출물은 살비아놀산 B(salvianolic acid B)와 로즈마린산(rosmarinic acid)을 50~70 : 10~30 중량비로 포함하는 혈전 형성 예방용 약학 조성물.
- 삭제
- 제 6 항에 있어서,단삼 추출물은 조성물 총 중량에 대하여 함량이 0.5중량% 이상인 것임을 특징으로 하는 약학 조성물.
- 제 6 항에 있어서,살비아놀산 B(salvianolic acid B)는 조성물 총 중량에 대하여 함량이 0.5중량% 이상인 것임을 특징으로 하는 약학 조성물.
- 제 6 항에 있어서,로즈마린산(rosmarinic acid)은 조성물 총 중량에 대하여 함량이 1.5중량% 이상인 것임을 특징으로 하는 약학 조성물.
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JPS64995A (en) * | 1987-06-23 | 1989-01-05 | Mitsubishi Electric Corp | Fluorescent display device |
KR100703182B1 (ko) | 2005-08-16 | 2007-04-06 | 건국대학교 산학협력단 | 단삼 추출물을 포함하는 혈전 예방 및 치료를 위한약학조성물 |
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JPS64995A (en) * | 1987-06-23 | 1989-01-05 | Mitsubishi Electric Corp | Fluorescent display device |
KR100703182B1 (ko) | 2005-08-16 | 2007-04-06 | 건국대학교 산학협력단 | 단삼 추출물을 포함하는 혈전 예방 및 치료를 위한약학조성물 |
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「천연물 (단삼) 성분 분석에 대한 연구」 보고서/ 1995, 강삼식 외 |
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단삼추출물의 항산화능 검색 및 약과에의 첨가효과/학국식품조리학회지 19권 4호/2003년/김윤화 외 |
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