KR100693293B1 - The water tissue and manufacture method of water tissue use of metallic Nano particles that have anti-fungi and smell exclusion function - Google Patents

Abstract

In the present invention, a non-preservative cleaning tissue having antifungal and odor removing function using nanoparticles of metal and a method of manufacturing the wet tissue have pulp or metal nanoparticles of 1 to 10 nanometers (nm) at a predetermined ratio. By using it in the processed water of the cleaning wipes formed of the nonwoven fabric, it is possible to simultaneously exhibit the effect of removing the bacterial odor without using a chemical preservative in the wet wipes.

Description

The water tissue and manufacture method of water tissue use of metallic nano particles that have anti-fungi and smell exclusion function}

1 is a transmission electron microscope (TEM) photograph and distribution diagram showing a state in which silver (Ag) particles are distributed in an average size of 7 nanometers (nm) in a wet tissue prepared according to the present invention.

FIG. 2 is a TEM photograph showing a particle size of silver (Ag) dispersed in an average of 1 to 2 nanometers (nm) in a wet tissue prepared according to the present invention.

The present invention applies metal nanoparticles of silver (Ag) to the cleaning wipes to give a strong antimicrobial power basically to remove the bacterial odor without using a chemical preservative to remove the nanoparticles of the metal for more hygienic use The present invention relates to a wet wipe for cleaning an antiseptic agent having an antifungal and odor removing function and a method for producing the wet wipe.

Generally, wet wipes are packaged and provided with moisture in pulp or non-woven tissue material, and chemical preservatives are used to prevent bacteria and mold from propagating under the influence of moisture during distribution and use. (For example, benzoic acid: Benzoic acid, sorbic acid: Sorbic acid, methyl paraben: Methylparaben, ethyl paraben: Ethylparaben, propyl paraben: Propylparaben, butyl paraben: Butylparaben, carbamate: 3-iodo-2-propynyl bytyl carbamate , Benzimidazoles: (4-thiazolyl) -benzimidazole, 2- (4-thiazolyl) -benzimidazole, benzalkonium chloride, polyvinyl butyal, diiodmethyl p-tollipsulfone, 2.4.5.6-terachloro Isobutyl nitrile, paraoxybenzoic acid, and the like ) .

However, even when the preservative is used below the legal limit in the preparation of wet wipes, it contains ingredients harmful to the human body that cause skin seizures, erythema and other skin irritation, which are common phenomena of the preservative. The risks caused by contact or long term skin contact may be more serious.

Moreover, even when antibacterial tissues were manufactured and distributed for sale, it was a common problem and a challenge for the industry to maintain anti-Fungi only when a certain amount of a preservative was used.

In addition, in some cases, even if silver ions (Ag ⁺ ) or chitosan and various chemicals having strong antibacterial properties are used to produce and sell antibacterial wipes, it is necessary to use a preservative separately.

Furthermore, even in wet tissue products made of metallic silver nanoparticles (ie, nano-silver) from pulp or nonwovens, molds and fungi, which are inherently present in the pulp or nonwovens, are also present. Or mold spores that may be mixed in the atmosphere during the production and processing of the wet tissues or molds present in the processed water used in the processing process are generally much stronger than the survival and reproduction of ordinary bacteria. Without the use of preservatives, it was difficult to control them.

That is, conventionally, since fungi have stronger viability and proliferative power than antimicrobial agents against conventional bacteria, it is difficult to maintain antifungal properties with conventional antimicrobial agents. Separate preservatives have been used.

Therefore, the present invention has been made to solve the above-mentioned problems of the prior art, and even if the nano-particles of the metal (Nano-Particle) is used, if the instantaneous strong anti-fungal (Anti-Fungi) does not exhibit the effect is obtained. In consideration of the difficulty, the silver preservative is used by using the silver nano-silver nanoparticles in the particle size of 1 to 10 nanometers (nm), and in the case of 1 to 2 nanometers (nm) in some cases. It is an object of the present invention to provide a wet wipe for cleaning an antiseptic and an odor removing function using nanoparticles of metal to have a strong anti-mildew and a bacterial odor removal effect without using it, and a method of manufacturing the wet wipe. .

In order to achieve the above object, according to a preferred embodiment of the present invention, in the method for producing antimicrobial wipes for imparting antimicrobial properties to wet wipes made of pulp or nonwoven fabric, the processed water of the pulp or nonwoven fabric Anti-mildew and odor removal by receiving and processing nano silver (silver (Ag) nanoparticles) of metal of 1 to 10 nm size, preferably nano silver (silver (Ag) nanoparticles) of metal of 1 to 2 nm size Provided is a method for preparing a wet tissue for cleaning an antiseptic having an antifungal and odor removing function using nanoparticles of a metal to be made.
Preferably, the nano-silver of the metal is a surfactant as a acceptor, silver nitrate (AgNO ₃ ) by dissociating the ion silver by silver ion (Ag) extracted by dissolving the silver and silver nitrate (AgNO ₃ ) It is ion-reduced to extract silver (Ag) of the metal and stabilized by using any one of silica, zeolite and zirconium phosphate as a carrier to dissociate nanosilver and silver nitrate (AgNO ₃ ). The silver (Ag) extracted from and combined with a polymer to increase the stability and dispersibility by the exposure of gamma rays, and any one or a combination of nano silver of the metal refined.
Also, when the silver (Ag) nanoparticles of the metal are 10 nanometers (nm) in size, the amount of the silver (Ag) nanoparticles is 0.0050 wt% to 0.0100 wt% (50 ppm-100 ppm), and the size is 1 to 2 nanometers ( nm), the amount is preferably 0.00004 wt% (0.4 ppm) to 0.0001 wt% (1 ppm).
In addition, the nano-silver of the metal is one of its colloidal phase and powder phase, and in the case of the colloidal phase, the solvent is selected from Pure Water, Isopropyl alcohol, and Ethanol.
According to another embodiment of the present invention by applying a nano silver of the metal to the material for wet wipes made of pulp or non-woven fabric to have antimicrobial properties, and in the cleaning wipes in the packaging of low density polyethylene film or polypropylene film, The nano silver (Ag nanoparticles) of the metal is contained in the processed water of the material in a size of 1 to 10 nm, preferably 1 to 2 nm, so that any one of deepening and spraying is performed. Provided is a non-preservative cleaning tissue having an antifungal and odor removing function using metal nanoparticles.

Hereinafter, with reference to the accompanying drawings, the present invention will be described in detail.

First, according to the present invention, the size of silver (Ag) nanoparticles of metals used in the preparation of cleaning wipes having anti-mildew and odor removing function is assumed to be 1 to 10 nm. The size is assumed to be 1-2 nm.

In contrast, when conventional nano silver is applied to wet tissue or other materials, at least 100 nm to 200 ppm or more of silver (Ag) nanoparticles can be maintained at least 100 ppm to 200 ppm to maintain anti-mildew. Silver (Ag) nanoparticles can maintain antifungal properties at concentrations of 200ppm ~ 400ppm or more has already been confirmed several times through the experiments of the official institutions, as in the present invention, especially silver (Ag) nanoparticles of less than 10nm in wet tissues In particular, the use of silver (Ag) nanoparticles having a size of 1 nm to 2 nm increases the total surface area, so that there is no example to maintain the instantaneous and excellent anti-mildew while minimizing the amount used.

The nanosilver (silver nanoparticles) used in the present invention is prepared by dissociating silver nitrate (AgNO ₃ ) with a surfactant as an acceptor and ion-reducing to extract silver (Ag) of a metal, and also silver nitrate (AgNO ₃ ). It is prepared by dissociating and ion-reducing to extract silver (Ag) of metal and stabilizing with silica, zeolite, zirconium phosphate, etc. as a carrier, and dissociating silver nitrate (AgNO ₃ ) to ion-reducing Extracting (Ag), binding the polymer to the base, enhancing stability and dispersibility by the exposure of gamma rays, and purifying the graphite or the like.

That is, the nanosilver used in the present invention is not specified as silver (Ag) nanoparticles of a metal produced by an electrical, chemical, or physical method, and any one or more combinations may be selectively used.

Meanwhile, according to the present invention, the ratio of efficiently using silver (Ag) nanoparticles of a metal is as follows.

In general, in order to increase the sterilizing power at a concentration ratio generally used, when the size is about 10 nanometers (nm), the amount of silver (Ag) nanoparticles used is 0.0050wt% to 0.0100wt% (50ppm to 100ppm). Increasing the amount of antimicrobial anti-fungal effects can be expected.

In addition, according to the present invention in order to obtain the anti-fungal anti-fungal effect of the silver (Ag) nanoparticles of the metal at 1ppm concentration (0.0001wt%) or less of 1 to 2 nanometers (nm) size Nano silver will be used.

In general, it is well known that the energy value of the outer surface is higher than the internal energy value of the material, as shown in the following formula, and since the nanonization means that the surface area is increased, this means that the energy value of the surface is high. It means losing.

delete

SV = Surface area of Particle Volume of Particle

= nas × d ² / nav × d ³ = as Of av × d

Where d: diameter of paticle

as: surface area shape factor (π)

av: volume shape factor (1/6 π)

Therefore, silver (Ag) nanoparticles having a size of about 1 to 2 nm are relatively high in the energy of the surface, so that the minimum amount of anti-fungal effect (Anti-Fungi) can be seen.

Nano-Silver (Ag nanoparticles) of the above-described metals are colloidal or powdered phases using a solvent as Pure Water, Isopropyl alcohol, Ethanol Includes.

According to the present invention, the silver of the metal dispersed in the processed water by impregnating (Deeping) or spraying the wet tissue material containing the metal nano silver (silver nanoparticles) in the above-described ratio pulp or non-woven fabric (Ag) If the nanoparticles are evenly distributed and packaged in pulp or nonwoven fabric, which is a wet tissue material, it is possible to prepare wet tissues without using a preservative in a chemical mixture.

Next, preferred embodiments will be described in order to explain the present invention more clearly and in detail. However, the present invention is not limited only to the examples.

EXAMPLE

(Example 1)

Diluted nanoparticle silver (Ag) nanoparticles of metals with an average particle size of 7 nm in a concentration of 10 ppm in general wet tissue manufacturing "MRSA (Methicillin Resistance S. aureus) ATCC As a result of testing the sterilization power of 33592 "as follows, it showed 99.9% sterilization power in one minute.

1. Test Result: Antibacterial activity (Shake Fla or Method-KS M 0146-2003)-1 minute after

Note) <= less than, CFU = Colony Forming Unit

2. Test method

Test condition: Test bacteria after 1 minute shaking incubation at 37 ± 1 degree Celsius (measuring number of shaking 120 times / min)

Test sample: 60㎠

Neutralization solution: Phosphate buffer (pH 7.0 ± 0.2)

Reduction (%): [(Mb-Mc) / Mb] × 100

Growth rate (%): Mb / Ma (more than 31.6 times)

Ma: Initial number of bacteria (average value) of control sample

Mb: Number of bacteria in the control sample after 1 minute incubation (average)

Mc: Number of bacteria in test sample after 1 minute incubation (average)

(Example 2)

According to the present invention, after the wet tissue was prepared in each case, the experiment was performed to observe the phenomenon of fungal expression and proliferation over a period of time, and the result is that when using 7 nm silver (Ag) nanoparticles, Considering the usual packaging and distribution conditions, it was found that the use of a concentration of 70ppm or more to maintain the anti-mildew.
In addition, in the case of using silver (Ag) nanoparticles having a size of 1 to 2 nm, it was observed that anti-mildew can be maintained at 0.4 ppm to 0.5 ppm.
Of course, it was observed that Bb (mold occurs 1 size of less than 0.5cm2) under conditions ① of normal phase (3rd period) at 0.4ppm concentration, but the size spreads to 0.1cm2 any more. It was determined that anti-mildew could be maintained because it was not grown and was tested in Shaale, not in low-density polyethylene (LDPE) packaging.

1. Preparation Sample:

end. 200 ml of metal silver (Ag) nanoparticles of average 7nm size are prepared in 10ppm, 20ppm, 30ppm, 40ppm, 50ppm, 60ppm, 70ppm, 80ppm, 90ppm and 100ppm concentrations

I. 200 ml of metal silver (Ag) nanoparticles with an average size of 1 ~ 2nm are prepared in 0.2ppm, 0.3ppm, 0.4ppm, 0.5ppm, 0.6ppm, 0.7ppm, 0.8ppm, 0.9ppm, 1.0ppm and 1.5ppm concentrations

All. Preparation of 1,200 sheets of polypropylene (PP; nonwoven) specimens (20mm × 30mm × 0.7mm, approx.2.4g)

2. Test method: Each sample is mixed and observed by the following method.

end. Each prepared nonwoven fabric specimen was mixed with about 7g (about 3 times the weight of the nonwoven fabric) of the processed water containing the silver (Ag) nanoparticles of the metal at each concentration, and then bonded and wrapped in three sides with a low density polyethylene transparent film. production

I. Each prepared nonwoven fabric specimen is mixed with about 7g (about 3 times the weight of nonwoven fabric) containing silver (Ag) nanoparticles at each concentration and sealed in a circular shalet to prepare 10 specimens.

All. 관찰 Phase 1 observation from October 27 to November 8, 2004 ㉡ Observation from November 8 to December 31 the same year as phase 2, ㉢ Phase 1 from January 1 to January 31, 2005 Observe until. The observation period was set in step # 1 considering the actual period of mold development and actual working conditions and circumstances in the wet tissue manufacturing process, and the rest of the phase was set to observe the persistence of antifungal properties.

The conditions for each observation period are ① natural light irradiation at room temperature (10 to 25 degrees Celsius), ② UV protection at room temperature, ③ UV protection at refrigeration (5 to 10 degrees in the image), and ④ The test was conducted under high temperature (between 40 and 50 degrees Celsius) and heated with warm air for 3 hours a day and opening the package. The condition of (4) is the most severe condition, and it is intended to see the change, not the condition that expects a certain expectation.

3. Judgment method

A: No change (no mold or bacteria)

B: Mold development (The mold generation range is less than 0.5 cm2)

C: Mold development (mold generation range is 0.5 cm 2 or more-less than 1 cm 2)

D: Mold development (mold generation range is 1 cm 2 or more-less than 1.5 cm 2)

E: Mold development (mold generation range is 1.5 cm 2 or more-less than 2 cm 2)

F: Mold development (The mold generation range is 2 cm2 or more)

a: no one out of 10 samples

b: 1 out of 10 samples

c: two or more out of ten samples

p: Test result in a sample of low density polyethylene packaging

s: the test result in the sample of Shaale

ps: results detected in both low-density polyethylene packaging and shale (measurement results Aa omit p, s, ps)

As described above, according to the method of manufacturing a wet wipe for cleaning an antiseptic having an antifungal and odor removing function using the nanoparticles of the metal according to the present invention, and a method for manufacturing the wet wipe, conventionally, bacteria and molds are propagated in the wet wipe manufacturing process. Chemical preservatives (Benzoic acid, Sorbic acid: Sorbic acid, Methylparaben: Methylparaben, Ethylparaben, Ethylparaben, Propylparaben: Propylparaben, Butylparaben: Butylparaben, Carbamate: 3-iodo- 2-propynyl bytyl carbamate, benzimidazoles: (4-thiazolyl) -benzimidazole, 2- (4-thiazolyl) -benzimidazole, benzalkonium chloride, polyvinyl butyal, diiodmethyl p-tollipsulfone, 2.4. 5.6- la Terre chloro acrylonitrile beuti isobutyl, p-benzoic acids, etc.) came to use, in the present invention, wet tissues processed in at least one non-toxic to the human body it is to silver (Ag) as a nano-scale usage By using a mixed eliminates the irritation caused by preservatives were able to get the hygienic effect of removing from bacterial odors.

Claims (5)

In the manufacturing method of the antimicrobial wipes which was made to give antibacterial treatment to the wet wipes material of pulp or nonwoven fabric, Into the processed water of the pulp or non-woven wet tissue material, nano silver (Ag) nanoparticles having a size of 1 to 10 nm, preferably nano silver (Ag) nanoparticles having a size of 1 to 2 nm, is used. Method for manufacturing a wet wipe for cleaning an antiseptic agent having antifungal and odor removing function using nanoparticles of metal, characterized in that the anti-mildew and odor removal by receiving and processing. The nanosilver of claim 1, wherein the nanosilver is prepared by extracting silver (Ag) of a metal by dissociating silver nitrate (AgNO ₃ ) and ion reduction by dissolving a surfactant as a receptor; Silver nitrate (AgNO ₃ ) is dissociated and ion-reduced to extract silver (Ag) of the metal and stabilized by using any one of silica, zeolite and zirconium phosphate as a carrier. Nano-Silver, which dissociates silver nitrate (AgNO ₃ ) to ion-reduce to extract silver (Ag) of metals, bonds polymers, and exposes gamma rays to increase stability and dispersibility, Method for preparing an antiseptic agent for cleaning an antiseptic agent having an antifungal and odor removing function using nanoparticles of a metal, characterized in that any one or combination thereof is included among nano-silver of purified metal such as silver ore. . The method of claim 1, wherein the amount of silver (Ag) is 0.0050wt% to 0.0100wt% (50ppm-100ppm) when the size of the silver (Ag) nanoparticles of the metal is 10 nanometers (nm). When the size of the silver (Ag) nanoparticles of the metal is 1 nanometer (nm) to 2 nanometers (nm), the amount of silver (Ag) is used at 0.00004 wt% (0.4 ppm) to 0.0001 wt% (1 ppm). Method for preparing a wet wipe for cleaning an antiseptic having antifungal and odor removing function using nanoparticles of a metal, characterized in that. The nanosilver of the metal is any one of its colloidal phase and powdered phase, In the case of the colloidal phase, the solvent is water (Pure Water), isopropyl alcohol (Isopropyl alcohol), ethanol (Ethanol) by using any one or a plurality of metals, characterized in that the anti-fungal and odor removal function using the nanoparticles The manufacturing method of the wet wipes of a preservative-free preservative which has. In the wet tissue which has antimicrobial property by applying metal nano silver to the wet tissue material by pulp or nonwoven fabric, The wet tissue material is accommodated in the processed water for wet tissues by containing 1-10 nm-sized metal nano silver (silver (Ag) nanoparticles), preferably 1-2 nm-sized metal nano silver (silver (Ag) nanoparticles). Deepening or spraying, An antiseptic agent having anti-mildew and odor removal function using nanoparticles of a metal, characterized in that the material for wet tissue in which silver (Ag) nanoparticles of the metal are dispersed is packaged in a wrapping paper of a low density polyethylene film or a polypropylene film. Cleaning wipes.

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