KR100651700B1 - 자기 입자들을 위한 고효율 자기 센서 - Google Patents

자기 입자들을 위한 고효율 자기 센서 Download PDF

Info

Publication number
KR100651700B1
KR100651700B1 KR1020027007883A KR20027007883A KR100651700B1 KR 100651700 B1 KR100651700 B1 KR 100651700B1 KR 1020027007883 A KR1020027007883 A KR 1020027007883A KR 20027007883 A KR20027007883 A KR 20027007883A KR 100651700 B1 KR100651700 B1 KR 100651700B1
Authority
KR
South Korea
Prior art keywords
magnetic
layer
sensing element
electrically conductive
layers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020027007883A
Other languages
English (en)
Korean (ko)
Other versions
KR20030022770A (ko
Inventor
게리 에이. 프린즈
마이클 엠. 밀러
Original Assignee
더 유나이티드 스테이츠 오브 아메리카 에즈 리프리젠티드 바이 더 세크리테리 오브 더 네이비
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 더 유나이티드 스테이츠 오브 아메리카 에즈 리프리젠티드 바이 더 세크리테리 오브 더 네이비 filed Critical 더 유나이티드 스테이츠 오브 아메리카 에즈 리프리젠티드 바이 더 세크리테리 오브 더 네이비
Publication of KR20030022770A publication Critical patent/KR20030022770A/ko
Application granted granted Critical
Publication of KR100651700B1 publication Critical patent/KR100651700B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/76Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids by investigating susceptibility
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11CSTATIC STORES
    • G11C11/00Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor
    • G11C11/02Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor using magnetic elements
    • G11C11/14Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor using magnetic elements using thin-film elements
    • G11C11/15Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor using magnetic elements using thin-film elements using multiple magnetic layers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Computer Hardware Design (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Magnetic Variables (AREA)
KR1020027007883A 2000-02-04 2000-08-17 자기 입자들을 위한 고효율 자기 센서 Expired - Fee Related KR100651700B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/497,754 US6468809B1 (en) 2000-02-04 2000-02-04 High efficiency magnetic sensor for magnetic particles
US09/497,754 2000-02-04
PCT/US2000/020782 WO2001057506A1 (en) 2000-02-04 2000-08-17 High efficiency magnetic sensor for magnetic particles

Publications (2)

Publication Number Publication Date
KR20030022770A KR20030022770A (ko) 2003-03-17
KR100651700B1 true KR100651700B1 (ko) 2006-11-30

Family

ID=23978168

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020027007883A Expired - Fee Related KR100651700B1 (ko) 2000-02-04 2000-08-17 자기 입자들을 위한 고효율 자기 센서

Country Status (6)

Country Link
US (3) US6468809B1 (https=)
EP (1) EP1299714A4 (https=)
JP (1) JP2003524781A (https=)
KR (1) KR100651700B1 (https=)
AU (1) AU2000267514A1 (https=)
WO (1) WO2001057506A1 (https=)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6468809B1 (en) * 2000-02-04 2002-10-22 The United States Of America As Represented By The Secretary Of The Navy High efficiency magnetic sensor for magnetic particles
EP1311854A2 (en) * 2000-08-23 2003-05-21 Imego AB Microfuidic device and method with trapping of sample in carities having lids that can be opened or closed
NO20014746D0 (no) * 2001-09-28 2001-09-28 Clas M Kjoelberg Smertelindrende middel
US7329392B2 (en) * 2001-10-19 2008-02-12 Sri International Device and method for handling reaction components
SE0103859D0 (sv) * 2001-11-20 2001-11-20 Sven Oscarsson Novel artificial structures with magnetic functionality
US6552554B1 (en) * 2001-12-06 2003-04-22 The United States Of America As Represented By The Secretary Of The Navy Testing current perpendicular to plane giant magnetoresistance multilayer devices
CN100343670C (zh) * 2001-12-21 2007-10-17 皇家飞利浦电子股份有限公司 用于测量微阵列上磁性纳米粒子面密度的传感器和方法
US7126331B2 (en) 2002-07-29 2006-10-24 The United States Of America As Represented By The Secretary Of The Navy Integrated gradiometer
JP2004117822A (ja) * 2002-09-26 2004-04-15 Toppan Forms Co Ltd 感熱発色性液体トナー受容層形成用塗工液およびそれを用いた感熱発色性静電印刷用シート
US7183120B2 (en) * 2002-10-31 2007-02-27 Honeywell International Inc. Etch-stop material for improved manufacture of magnetic devices
JP4399211B2 (ja) 2002-12-21 2010-01-13 株式会社ハイニックスセミコンダクター バイオセンサー
US7906345B2 (en) 2003-11-12 2011-03-15 The Board Of Trustees Of The Leland Stanford Junior University Magnetic nanoparticles, magnetic detector arrays, and methods for their use in detecting biological molecules
JP2005315678A (ja) * 2004-04-28 2005-11-10 Canon Inc 検出方法、検出デバイス及び検出用キット
EP1751534A1 (en) * 2004-05-18 2007-02-14 Koninklijke Philips Electronics N.V. Magnetic rotation to improve signal-over-background in biosensing
US20090224755A1 (en) * 2004-11-30 2009-09-10 Koninklijke Philips Electronics, N.V. Means and method for sensing a magnetic stray field in biosensors
JP4756868B2 (ja) * 2005-01-31 2011-08-24 キヤノン株式会社 検出方法
US7304360B2 (en) 2005-07-12 2007-12-04 Magic Technologies, Inc. Method of forming super-paramagnetic cladding material on conductive lines of MRAM devices
US7696548B2 (en) * 2005-08-09 2010-04-13 Magic Technologies, Inc. MRAM with super-paramagnetic sensing layer
US8512559B2 (en) * 2005-11-18 2013-08-20 Intel Corporation Device, method, and system for separation and detection of biomolecules and cells
DE102006016334B4 (de) * 2006-04-06 2018-11-15 Boehringer Ingelheim Vetmedica Gmbh Verfahren und Vorrichtung zur Detektion magnetisierbarer Partikel
US8133439B2 (en) 2006-08-01 2012-03-13 Magic Technologies, Inc. GMR biosensor with enhanced sensitivity
JP5207668B2 (ja) * 2007-06-22 2013-06-12 キヤノン株式会社 検出装置及び検出方法
CN101868286A (zh) 2007-09-20 2010-10-20 马格雷股份有限公司 采用磁性传感器进行的分析物检测
WO2009037636A1 (en) * 2007-09-21 2009-03-26 Koninklijke Philips Electronics N.V. Sensor with high frequency ac magnetic field
JP4911471B2 (ja) * 2007-11-06 2012-04-04 国立大学法人東京工業大学 バイオセンサ用マーカ、バイオセンサ、及びバイオセンサ用マーカ検出方法
EP2240773A2 (en) * 2007-12-18 2010-10-20 Koninklijke Philips Electronics N.V. A magnetic sensor device
US7977111B2 (en) * 2008-01-18 2011-07-12 Magic Technologies, Inc. Devices using addressable magnetic tunnel junction array to detect magnetic particles
US8053244B2 (en) * 2008-08-13 2011-11-08 Seagate Technology Llc Magnetic oscillator based biosensor
EP2401625B1 (en) * 2009-02-26 2014-01-22 Regents of the University of Minnesota High magnetic moment particle detection
US8334147B2 (en) * 2009-05-26 2012-12-18 Magic Technologies, Inc. Bio-sensor with hard-direction field
US8444920B2 (en) * 2009-09-16 2013-05-21 Weiqun Liu O-ring systems and methods for quantification of multiplex biomarkers in multiple samples
KR101093776B1 (ko) 2010-01-21 2011-12-19 충남대학교산학협력단 자기 센서
KR101157997B1 (ko) * 2010-08-19 2012-06-25 주식회사 엘지생명과학 자기저항센서를 이용한 검출시스템
US20140099663A1 (en) * 2010-11-15 2014-04-10 Regents Of The University Of Minnesota Gmr sensor
JP6101215B2 (ja) 2011-03-09 2017-03-22 マグアレイ,インコーポレイテッド サンプル中の分析対象物に対するハイスループット検出を行うシステム及び方法
US10739337B2 (en) * 2011-08-30 2020-08-11 Board Of Trustees Of Michigan State University Extraction and detection of pathogens using carbohydrate-functionalized biosensors
US9927431B2 (en) 2011-09-14 2018-03-27 Regents Of The University Of Minnesota External field—free magnetic biosensor
CN103987654A (zh) 2011-10-19 2014-08-13 明尼苏达大学董事会 用于高吞吐量生物分子测试的磁性生物医学传感器和感测系统
JP6117706B2 (ja) * 2012-01-04 2017-04-19 トヨタ自動車株式会社 希土類ナノコンポジット磁石
US20140167786A1 (en) * 2012-12-14 2014-06-19 Schneider Electric USA, Inc. Current Sensor For Power Measurement Applications
JP6422935B2 (ja) 2013-03-15 2018-11-14 マグアレイ,インコーポレイテッド 磁気トンネル接合センサ及びその使用方法
US10145906B2 (en) 2015-12-17 2018-12-04 Analog Devices Global Devices, systems and methods including magnetic structures
PT110107B (pt) 2017-05-26 2021-11-16 Univ Aveiro Elemento de sonda e métodos para separação e deteção de analitos controlada por temperatura
US11940502B2 (en) 2021-09-24 2024-03-26 Analog Devices International Unlimited Company Magnetic field sensing based on particle position within container
EP4381305A1 (en) 2021-09-24 2024-06-12 Analog Devices International Unlimited Company Magnetic field sensing based on particle position within container
US12613147B2 (en) 2021-11-12 2026-04-28 Analog Devices International Unlimited Company Temperature sensing with particles in medium material
CN114739544B (zh) * 2022-02-23 2024-06-14 万津实业(赤壁)有限公司 压力监测膜片、组件及压力监测方法
CN114777964B (zh) * 2022-04-02 2024-07-09 太原理工大学 一种磁流变弹性复合薄膜表面应力生物传感器
US12435803B2 (en) 2022-05-27 2025-10-07 Analog Devices International Unlimited Company Flow adjustment based on particle movement in response to magnetic field
US12379433B2 (en) 2022-09-14 2025-08-05 Analog Devices International Unlimited Company Magnetically sensitive particles and magnetic structure
CN120085232A (zh) * 2025-01-24 2025-06-03 哈尔滨工业大学 一种磁矩测量系统及测量方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4225239A (en) * 1979-07-05 1980-09-30 The United States Of America As Represented By The Secretary Of The Navy Magneto-optic bias of ring laser using reflective magneto-optic element at near-grazing incidence
JPS63108264A (ja) * 1986-10-25 1988-05-13 Nippon Telegr & Teleph Corp <Ntt> 磁気免疫測定方法および該方法を実施するために使用する検査試薬片
US4823177A (en) * 1988-06-30 1989-04-18 United States Of America As Represented By The Secretary Of The Navy Method and device for magnetizing thin films by the use of injected spin polarized current
US5025416A (en) * 1989-06-01 1991-06-18 The United States Of America As Represented By The Secretary Of The Navy Thin film magnetic memory elements
TW199858B (https=) * 1990-03-30 1993-02-11 Fujirebio Kk
JP2938936B2 (ja) * 1990-06-15 1999-08-25 ティーディーケイ株式会社 抗原又は抗体の濃度測定方法
DE69333569T2 (de) * 1992-03-20 2005-08-04 Abbott Laboratories, Abbott Park Magnetisch assistierte bindungsassays unter verwendung von magnetisch markierten bindungspartnern.
JPH08503336A (ja) * 1992-11-16 1996-04-09 ノンボラタイル エレクトロニクス,インコーポレイテッド 合金層を有する磁気抵抗性構造
US5475304A (en) * 1993-10-01 1995-12-12 The United States Of America As Represented By The Secretary Of The Navy Magnetoresistive linear displacement sensor, angular displacement sensor, and variable resistor using a moving domain wall
US5477482A (en) 1993-10-01 1995-12-19 The United States Of America As Represented By The Secretary Of The Navy Ultra high density, non-volatile ferromagnetic random access memory
DE19503664C2 (de) * 1995-01-27 1998-04-02 Schering Ag Magnetorelaxometrische Detektion von Analyten
US5541868A (en) 1995-02-21 1996-07-30 The United States Of America As Represented By The Secretary Of The Navy Annular GMR-based memory element
JPH1078409A (ja) * 1996-09-03 1998-03-24 Kayaba Ind Co Ltd 流体センサ
US5981297A (en) 1997-02-05 1999-11-09 The United States Of America As Represented By The Secretary Of The Navy Biosensor using magnetically-detected label
US6468809B1 (en) 2000-02-04 2002-10-22 The United States Of America As Represented By The Secretary Of The Navy High efficiency magnetic sensor for magnetic particles

Also Published As

Publication number Publication date
US6844202B2 (en) 2005-01-18
US20020197739A1 (en) 2002-12-26
KR20030022770A (ko) 2003-03-17
US20030049869A1 (en) 2003-03-13
AU2000267514A1 (en) 2001-08-14
WO2001057506A1 (en) 2001-08-09
US6764861B2 (en) 2004-07-20
EP1299714A1 (en) 2003-04-09
EP1299714A4 (en) 2005-03-30
US6468809B1 (en) 2002-10-22
JP2003524781A (ja) 2003-08-19

Similar Documents

Publication Publication Date Title
KR100651700B1 (ko) 자기 입자들을 위한 고효율 자기 센서
EP2390651B1 (en) GMR biosensor with enhanced sensitivity
TWI295323B (en) Sensor and method for measuring the areal density of magnetic nanoparticles on a micro-array
JP5161459B2 (ja) 磁性検出器アレイ、および生物学的分子の検出におけるそれらの使用方法
EP2274633B1 (en) Spintronic magnetic nanoparticle sensors with an active area located on a magnetic domain wall
JP4731927B2 (ja) 磁性体センサおよび検出キット
JP4756868B2 (ja) 検出方法
JP5279340B2 (ja) 標的物質検出キットおよび標的物質検出方法
US7651871B2 (en) Device for forming magnetic well for nanoparticles
Hung et al. Biomedical Diagnosing Lab-on-a-Chip
WO2001027592A1 (en) Magnetizable bead detector
Osterfeld et al. MagArray biochips for protein and DNA detection with magnetic nanotags: design, experiment, and signal-to-noise ratio
Djamal Giant magnetoresistance material and its potential for biosensor applications

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20091124

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20091124

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000