KR100553576B1 - Functional healthy cadence good stuffs and manufacturing method thereof - Google Patents

Abstract

The present invention relates to a functional dietary supplement and a method for manufacturing the same, and more particularly, to collect wild buckwheat, algae grass, honeysuckle, licorice, marshmallow, dandelion, white tea, marigold, and chajeoncho in natural herbal medicines; A step of heating the dried herbal medicines into each heating container together with a solvent obtained by mixing any one or two or more of water, ethanol, methanol, isopropyl alcohol, n-hexane, chloroform and acetone; Filtering each extract obtained by heating and concentrating the filtered extract under reduced pressure and then drying; It is made by mixing the extract (extract) of each herbal medicine obtained by drying at a predetermined ratio.

Detoxification, Hazardous Ingredients, Nicotine, Solvent

Description

Functional healthy cadence good stuffs and manufacturing method

The present invention relates to a functional dietary supplement and a method of manufacturing the same, and more particularly, to collect wild buckwheat, algae grass, honeysuckle, licorice, marshmallow, dandelion, white tea, marigold, and chajeoncho among natural herbal medicines and dried each of them. The herbal medicines are heated and concentrated together with the solvent, and then each dried herbal medicine is mixed in a certain ratio to remove or prevent toxic components in the human body caused by smoking and chemical poisons caused by inhalation of pollution and taking various drugs. The present invention relates to a functional dietary supplement for removing harmful components in a human body and a method of manufacturing the same.

There are many substances and elements that harm people's health, but the most damaging is tobacco. These cigarettes are the largest preventable cause of death in our time. The research on the relationship between smoking and disease has been intensively studied since the mid-1900s, and there is continuous evidence for the increase in the incidence of various diseases such as lung cancer caused by smoking and other health disorders. In fact, about 4,000 kinds of components were found in cigarette smoke as early as present, and it is estimated that there are more than 100,000 kinds of components in mainstream smoke.

About 4000 of these components make up more than 95% of the total mainstream annual volume, and thousands of other components are present in extremely small amounts. Tobacco smoke is caused by the incomplete combustion of tobacco, and if completely burned, only water and carbon dioxide are produced. Incomplete combustion is caused by incomplete combustibility of some tobacco leaf components, insufficient oxygen supply and temperature difference when the cigarette burns, and also occurs through the process of distillation, sublimation, pyrolysis, thermal synthesis, and volatility when the cigarette burns.

Tobacco smoke is an aerosol, a mixture of liquid or fine particles in a gas that passes through a Cambridge glass fiber filter (which can filter 99% or more of particles larger than 0.1 µm in diameter). A substance is called a gas or vapor component and consists of nitrogen (59%), oxygen (13.4%), carbon dioxide (13.5%), carbon monoxide (3.2%), and is toxic to bronchial cilia. Volatile components having low molecular weights such as aldehydes, ketones, alcohols and esters, etc. The material filtered by the Cambridge Grass Fiber Filter, called Particulates phasecomponents, accounts for about 8% of tobacco smoke and contains at least 38 known carcinogens, including carcinogenic and carcinogens, and nicotine. And organic chemicals.

According to a recent study, cigarettes are expected to remain the biggest risk factor for human health in the 21st century, and to grow in size. Nevertheless, it is not easy for a tobacco lover to quit smoking habits, and there is no easy means to eliminate various diseases caused by smoking while continuing to smoke.

The present invention creates an extract by heating the detoxification effect in the human body by adding an aqueous solvent to each of natural herbal medicines, namely, buckwheat, algae, honeysuckle, licorice, marshmallow, dandelion, baekjiryeo, marigold, and chajeoncho, and extract the extract from the solid residue. After separating, concentrating and drying to obtain a solid, each obtained product may be mixed at a predetermined ratio to remove or prevent toxic components in the human body due to smoking, and chemical poisons caused by inhalation of pollution and taking various drugs. The purpose is to provide a functional dietary supplement that removes harmful components in the human body.

The composition of the herbal extract manufacturing method for removing the toxic components in the human body of the present invention for achieving the above object, the step of collecting and drying weak hair wheat, dendritic grass, honeysuckle, licorice, marshmallow, dandelion, white tea, marigold, chajeoncho; A step of heating the dried herbal medicines into each heating container together with a solvent obtained by mixing any one or two or more of water, ethanol, methanol, isopropyl alcohol, n-hexane, chloroform and acetone; Filtering each extract obtained by heating and concentrating the filtered extract under reduced pressure and then drying; It consists of a step of mixing the extract (extract) of each herbal medicine obtained by drying at a predetermined ratio.

In addition, the extract ratio of each herbal medicine (extract) is 5 ~ 40% by weight of wild buckwheat, 5 ~ 20% by weight of algae grass, 5 ~ 30% by weight of honeysuckle, 0.5 ~ 10% by weight licorice, 5-40% by weight of dandelion, dandelion 5 to 20% by weight, chlorophyll 0.5 to 10% by weight, marigold 0.5 to 10% by weight, chajeoncho 5 to 20% by weight of the mixture, the amount of the solvent added to the herbal medicine is 5% by weight solvent in the herbal medicine ~ 50 times, the heating temperature and time of the solvent added to the herbal medicine is 0.5 ~ 5 hours at 25 ℃ 100 ℃.

In addition, the functional dietary supplement to remove the toxic components in the human body is made of any one selected from powder, granules, tablets, or capsules.

When explaining the ingredients, efficacy and action for each herbal medicine used in the functional health supplement of the present invention prepared by the above method.

Houttuynia cordata Thunb (Polypara cordata Bueck) is also known as Chinese herb, nectar, saengcho, ten, and three hundred s, with plant stems and leaves.

The main component is methylnonylkenone CH ₃ (CH ₂ ) ₈ COCH ₃ (oxidation product of decanoyl acetaldehyde) myrcene C ₁₀ H ₁₆ , laurin aldehyde C ₁₁ H ₂₃ CHO, caprinaldehyde C ₉ H ₁₉ CHO, capr It is an acid, and there are many other ingredients, and the leaves contain urea citrate and 2.7% of inorganic compounds released in water.

Cuercitrin has urinary action (concentration of 100,000 times) and cardiac action, and antibacterial action against E. coli, typhoid bacteria, paratyphoid bacteria, erythropoies, gonococci, staphylococcus bacteria, filamentous fungi and capillary strengthening.

Decanoyl acetaldehyde has an antibacterial action against non-pathogenic fungi, as well as ringworm and athlete's foot fungi, as well as fungi against staphylococcus aureus, gonococcus and anti-acid bacteria. Antimicrobial activity against staphylococcus is 1: 40,000 and is stronger than sulfa.

Its application is an inflammatory drug and diuretic detoxification agent, which is used for gonorrhea and urethritis, cystitis, uterusitis, pneumonia, bronchitis, bite, athlete's foot treatment, prolapse, swelling, windworm, sinusitis.

As a private prescription, juice is produced, and it is attached when athlete's foot, athlete's foot, hemorrhoids, snake venom, and lacquer rise. Leaves and stems are used for swelling and peeing, and the roots are used for wind poison and swelling.

Geranium nepalense Sweet (G. thunbergii Siebold et Zuccarini) is another name, also called hyacinth, using the stem and leaves of the plant.

The main components of the outpost are pyrogalgaltanin, glutinous acid, succinic acid, quercetin and its glycosides, and camphorol and camphortrin C ₂₇ H ₃₀ O ₁₄ 3 1 / 2H ₂ O (dhamnoside of camphorol).

According to other sources, tannins, which are based on geranine, a type of ellagtanine, have also been identified in the outpost, including protocatechinic acid, pyrogallol, ellagic acid, brevifoline, and corylazine.

Tannin content is 4.7% in outpost, 20.3% in leaves, 3.8% in stems and 4.6% in roots. The content in leaves is highest in June and August and the lowest in winter.

The main action is the water extract or alcohol extract of the outpost to increase the tension of the intestine. Diarrhea is as clear as bismuth preparation, no side effects and large amounts of use, do not drop the taste of the bacterium, typhoid bacteria, E. coli bactericidal action.

Honeysuckle (Lonicera japonica Thunb) is another name, also known as gold and silver mistletoe, using the stem and leaves of the plant.

The components include luteolin C ₁₅ H ₁₀ O ₆ (5,7,3,4-tetrahydroxyflavones) and inositol C ₆ H ₁₂ O _6. The flowers are inositol and lead-like substances (ceryl alcohol, sterol) , Arachnic acid, myristic acid, ellidinic acid, linoleic acid, linoleic acid).

The leaves and stems contain 5-8% tannins, and the leaves contain loganine, about 19% nitrogen-containing substances, and roniserine C ₂₇ H ₃₀ O ₁₅ 2H ₂ O, luteolin-7-rhamnoglucoside. .

Iridoid compounds roniseiroid and sweroside were isolated from the leaves of the same genus L. morronii.

As a function, flower decoction has the effect of urinating and increasing blood sugar, and also has a bactericidal effect on red bacteria, typhoid bacteria, staphylococci, and pneumococci. There is also a protective effect of peptic gastric ulcer, sympathetic nerve excitement, smooth muscle paralysis.

It is used in motion therapy when it is opened in early stages of wind, with flowers, leaves, stems, fever medicines, poisonous medicines, urine medicines, and sperm medicines. Many different types of washing are washed away. It burns like charcoal and is used by medicine.

Private prescription is used to treat cancer. It is good for stomach cancer if you eat it like water for a long time. In particular, it is washed or tingled with endometritis, lymphadenopathy fistula and ophthalmitis.

Licorice (Glycyrrhiza glabra L.) is also known as Guk-ro, straight licorice, sensational herb and uses plant roots.

Roots and root stems are carved out in the autumn, trim the stems, rinse in water and dry in the sun.

The rhizome and root glycyrazine content is higher in autumn than in summer. The glycyrazine content of biennial licorice is 3.8% in April, 3.7% in May, 3.3% in July, 3.8% in August, 5% in September and 6% in October.

The content of glycyrrhizin along the roots is 6.91% for the root of the biennial licorice and 8.04% for the thin root. Therefore, it is reasonable to use not only the root and root stem as medicine, but also the root. Also, the skin (13.06%) is higher than the neck and water (10.42%). When peeling, only the corked skin should be peeled off, so that the skin is not damaged.

The root and stem include glycyrrhizin (potassium or calcium salt of glycyric acid) of 5-14% (many of which are 23%) and glabraic acid (glycitretin) C ₃ 0H ₄₆ O ₅ .

Glycilisic acid C ₄₂ H ₆₂ O ₁₆ is triterpenoid saponin, melting point 205 ℃, decomposition point 220 ℃, [d] D20 +58.5., Well soluble in alcohol and hot water, not soluble in ether. After cooling in hot water, it hardens like grass. Decomposition of water gives tasteless glycyrrhetinic acid C ₃₀ H ₄₆ O ₄ and two molecules of glucuronic acid C ₆ H ₁₀ O ₇ .

Glycyretinic acid is a β-amirin-based triterpenoid, which has two kinds of α and β substances, which are easily changed. But its esters do not change from one another. α-glyciletin acid is a plate-like crystal (dilute alcohol), melting point 283 ° C., [α] D20 + 140. (ethanol), soluble in ethanol, dioxane and chloroform. β-glyciletin acid is needle crystals (ethanol) and has a melting point of 296 to 300 ° C. [α] D20 + 86. It is (alcohol) and soluble in ethanol, pyridine, acetic acid and poorly soluble in petroleum ether.

In addition, flavono glycosides, liqueurin C21H22O9, neoriquiritin, and ramnoricuritin (all of which are non-glycolic) are the corresponding glycon glycosides called isoricuiritin, neoisoricuiritin, Isoram noriquiritin and liqueur seed (all of these non-sugars are Isorikuuriritenin). Rhamnoricuritin is also called liqueuritoside.

More than 27 flavonoid analogs were identified by chromatograph in licorice root.

Β-sitosterol, formmononetin, ricolycidine, lycoricone, and ricore-oligonane were identified in the roots of curved licorice. In addition, dry leaves and stems when flowering can be used as house animal feed with 14-22% protein, 2-5% oil, 36-62% nitrogen-free extract, and 5-20% ash.

Flavonoid content in licorice changes with the season of growth. It is the highest when the roots start to fall, and the leaves and stems have fruit. In the fall, the content of liqueur seeds is about 0.5%. Licuraside accounts for about 10% of the total flavonoids.

Stems and leaves include saponaretin, glyphoside and bitexin. Saponaretin is about 50% of the total flavonoids and 3% in the outpost when fruit is opened.

Glyceramarin with a bitter taste (gitter component of glycyrrhizin), 2,4,4-trihydroxy sigalcon and its glycosides Dioxystiggsterol (melting point 135 ~ 136 ℃), β-sitosterol, essential oil (0.03%) , 11-30 mg% ascorbic acid, asparagine (1-4%), fructose (2.4-6.5%), glucose (2-4%) mannitol, starch (14-30%), rubber (1.5-4%), yellow Bovine, malic acid, oil, resin, tannin, protein and amino acids include aspartic acid, proline, alanine, threonine, serine, glycine, valine, isoleucine, and γ-aminobutyric acid. The most bitter substance is 8%. Among them, 2.5 ~ 3% of the water is released.

Glycirizine, which is known as an active ingredient of licorice root, has a sweet taste of about 40 to 50 times that of candy, and its sweetness can be felt even in a diluted solution of 100,000 times. The water solution foams when shaken, but is weaker than normal saponins and has no or hemolytic action (potassium salt is 1: 400). The glycyrrhetinic acid produced by the hydrolysis of glycyrrhizin is not sweet and hemolytic. Thus, the expectorant action of licorice is presumed to be due to glycyrrhetinic acid. Glysirizine also relieves the respiratory system.

Licorice root extract and glycyrrhizin are non-toxic and relieve poisoning by catcherchloral, strycnin, yohimbine, cocaine, morphine, codeine, atropine and luminal. Releases bacterial and viral toxins such as tetanus toxin, diphtheria toxin and snake venom.

It antagonizes with acetylcholine, histamine, and allergens, and has an adrenaline-like effect.

The poisonous action of glycyrrhizin is related to glucuronic acid, a product of water degradation. Glucuronic acid is a component widely found in animal and plant systems and is combined with toxic substances in the liver to form glucuronide and excreted by urine. Therefore, glucuronic acid is used for drug poisoning, alcohol poisoning, food poisoning, jaundice, cirrhosis of the liver, chronic liver, rheumatism, joint pain, nerve pain.

The detoxification of glycyrrhizin is not thought to be caused solely by glucuronic acid, but is also related to the action of glycyrazine similar to that of corticosteroids. Glycirizine has the same effect as desoxycorticosterone, the corticosteroid.

Glycyretinic acid reduces the excretion of sodium, chlorine and urine and increases the excretion of potassium in animal experiments.

That is, the ratio of Na / K is lowered. As such, it negatively affects potassium metabolism but positively affects sodium metabolism. It also acts to reduce the ascorbic acid content of the adrenal cortex, which sets conditions to enhance the effects of corticosteroids on water and salt metabolism. This action is also present in licorice extract and glycyrrhizin. The same thing happens when people eat.

Licorice root extract glycyrrhizin is anti-inflammatory. In other words, it has a positive effect on the treatment of experimentally induced formalin arthritis in animals. It inhibits the activity of serum transaminase and increases the activity of adenosine triphosphatase in the liver. The anti-inflammatory action of glycyrrhizin similar to desoxycorticosterone is believed to be due to the degradation product glycyrrhetinic acid.

There is also a view that the corticosteroid-like action of glycyrizine inhibits the reduction of the inactive Δ4-3 ketone moiety in vivo.

Licorice root extract has antispasmodic effect similar to papaverine on gastrointestinal smooth muscle in animal experiments. This action is due to the flavonoid component. Licorice flavonoids, which have not been used until now, was developed with known antifungal and anti-inflammatory effects. Licuraside, a flavonoid component, has three times as hard as papaverine and has anti-inflammatory and anti-ulcer activity. And antagonists of acetylcholine and histamine.

Licorice root extract has been known to have a therapeutic effect on peptic ulcer disease in the 1950s. Thus, many experiments have been carried out to find anti-ulcer substances in licorice roots. In the 1960's, flavonoids were obtained and the components were found to work hard. In addition, recent experiments have shown that there are anti-inflammatory and anti-ulcerative effects as well as palliative action.

Licorice has a strong surface activity, so if you eat it with other copper medicines, it helps loosen the ingredients in water to help absorption. It also reduces the toxicity of the medicinal herb and changes the taste.

Licorice root has a slight inhibitory effect against Staphylococcus aureus, Escherichia coli, and Lycobacteria.

When glycyrrhizin is used with anti-cancer drug thiopoxamide, anti-cancer activity reaches 85-95%.

Applications include liquorice sputum cutting, palliative action, anti-inflammatory and anti-inflammatory action, and antihistamine action.

Therefore, sputum acupuncture is used for upper gastrointestinal diseases, because it has a sweet taste, it is also used as a drug in the medicine. It can also be used as a poison or medicine. Nowadays, it is widely used for gastroduodenal ulcers, Edison disease, bronchial asthma, jaundice and hepatitis, eczema and skin diseases.

Glycyrrhizin is used as a supplement to increase the activity of anticancer drugs.

In motion therapy, the roots are often used for the purpose of mitigating and harmonizing the actions of other medicines in motion. In other words, when used with a hot medicine to relieve heat, and when used with a cold to relieve the cold.

Like palliative medicine or pain 멎 jinjak, sputum pill, cough 멎 yipo, poison pool medicine stomach cramps, stomach pain, sore throat, stomach ulcers, duodenal ulcers and enter into a poisonous prescription.

Rubia (Rubia cordifolia L. var. Mungista Miquel (R. akane Nakai), also known as Cheoncho and Hongcheon, uses plants' flowers and leaves.

In the root, oxanthraquinone pigment purpurin C ₁₄ H ₈ O ₅ , pseudopurpurin, pseudopurpurin-xylo-glucoside, moongistine, and moongistine-glucoside were separated.

At the roots of R. tinctorum L. and cordifolia L. are alizarin C ₁₄ H ₈ O ₂ and its glycosides, rubitriric acid C ₂₅ H ₂₆ O ₁₃ , galiozin C ₁₅ H ₈ O ₇ , xanthapurpurin C ₁₄ H ₈ O ₄ , furfuroxanthin, rubiandin glycosides, furfuroxanthincarboxylic acid, rubidine and the like. In addition, there are lemon acid, malic acid, grape acid, sugar, pectin. The leaves contain organic acids and trace alkaloids and flavonoids.

Where it works, the root decoction slowly destroys kidney stones and bladder stones. This mechanism of action was initially thought to be due to acidification of urinary acid to dissolve urine in calcium phosphate. Nowadays, chemically similar pigments in the roots dissolve by acting with calcium phosphate to dissolve acidic urine so that the citrate dissolves quickly.

Root preparations do not affect arterial pressure and respiration, but strengthen heart contractions. However, it does not have a clear effect on the heart rhythm. And the pendulum penetrates hard and raises tension. It also has a pissing action and acts as a fungus against cocci. Root preparations reduce the tension of the pyelone and bladder smooth muscles and increase the peristaltic contractions of muscle fibers, making the movement of stones absent. Therefore, the therapeutic effect of this drug is especially good for spasm of urethral smooth muscle.

Root dry extract, root powder, total glycosides and ruberic acid were compared and tested. This formulation urinates better than other formulations and has a more pronounced hardening effect. It also reduces the coagulation time.

Applications include nephropathy, prevention of recurrence after stones and inflammatory phosphate urine. Magnesium phosphate, calcium phosphate stones have good therapeutic effect.

When you take this medicine, the stones become rough, punctured and pink. After 3-4 hours of medicine, the urine turns red. Enough amount should be used to pee the rose.

In motion therapy, it is used when there is no menstruation, endometritis, vomiting or bleeding, and when urine is mixed with blood.

Folk prescriptions include swelling paralysis, fever-lowering medicine, especially when the lungs and liver have a fever, phlegm medicine for colds, pneumonia, sore throat and

It improves blood circulation, and writes at the right time. It is also used as a pain medicine, Jingyeong medicine, and antiseptic, and is said to be effective against malignancies. In addition to anti-inflammatory effects,

Estrogen activity, blood activity, jingyeong, expectoration, tonic, blood pressure lowering, mercury absorption is also effective.

Dandelion (Taraxacum platycarpum H. dahist) is also called Pogongyoung, and it is dried in the sun and used in the sun.

The main ingredient is lactosphyrin (which is decomposed into lactocin and p-oxyphenylacetic acid), talaxacin, γ-amirin, taraxerol C ₃₀ H ₅₀ O, caffeic acid, β-cystoterol and stigma Sterols, p-coumaric acid, serotonic acid, tannins, choline. Arnidiol C ₃₀ H ₅₀ O ₂ (melting point 257 ° C), paridiol C ₃₀ H ₅₀ O ₂ (melting point 236 ° C), which is a triterpene alcohol, and taraxasterol C ₃₀ H ₅₀ , which is a sterol compound, in the milk tube O (melting point 220 ~ 221 ℃), Pseudotaraxasterol C ₃₀ H ₅₀ O (melting point 217 ~ 219 ℃), the yellow of the flower is mainly C ₄₀ H ₅₆ O ₃ . The outpost contains the flavonoids cosmosine, luteolin-7-glucoside, 6-10 mg% carotene, 6-62 mg% ascorbic acid and vitamin B1 B2 D on the leaves.

As a function of the outpost has an Idam activity. In addition, the secretion of gastric juice is faster and urinary action has a therapeutic effect on the portal bite.

Its application is hepatobiliary disease medicine, physiological digestive medicine, rice flavoring medicine, and is widely used in the nutritional diet of patients with recovery period.

In the treatment of motion, placebo, urinary medicine, or blood donation, indigestion, gastritis, stomach ache, lactation, stiffness, squeezing and peeing, used to stop colds, sore throat, and eye disease.

As a folk medicine, it is used for cough, pulmonary tuberculosis and urinary medicine, nephropathy, and inflammatory medicine for colitis and gastric ulcer.

Tribulus terrestris L is also known as Chewy, Jajiryeon, or Ji-yul.

The main components are saponin 1.47%, essential oils, alkaloids, resins, oils.

It is said that the application is to remove the blood pill, old blood from the motion therapy. Used to protect the kidneys and for eye diseases. It is also used for pissing and inflammatory medications, which have little hair and milk.

Calendula officinalis L., also known as calendula, uses petals that are dried in shade.

The main ingredients are carotene, lycopene (melting point 175 ℃), violaxanthin C ₄₀ H ₅₆ O ₄ (melting point 207 ~ 208 ℃), rubyxanthin (melting point 160 ℃), neoricopin A, citraxanthin (melting) Flavonoids such as 163-164 ° C) and clavochrome (melting point 184-185 ° C). The content of carotenoids is about 3%. Flowers contain 0.02% essential oils, about 3.4% resins (about 1.5% nitrogen content), albumin 0.64%, 6.84% organic acids calculated from malic acid, red salicylic acid and alkaloids.

Above ground, there are bitter substances calenden C23H38O7, saponin (which breaks down into oleanolic acid and glucuronic acid), and unsaturated triterpendiol arnidiol, paradiol and tannin (6-7%). Seeds include alkaloids, oils (primarily glycerides of lauric acid and palmitic acid), and seryl alcohol and phytosterol in the unsaponified portion of oil.

As a function, flower decoction, alcohol extract, and juice have a calming effect on the central nervous system in animal experiments and lower reflex excitability. It also lowers blood pressure, hardens heart contractions, and slows down the heart. There is also bactericidal action.

The application is to make plaster and apply it to burns, ulcers, dentitions, sharp peaks, and sharp peaks. Also, rainforest medicine and tincture are affected by ophthalmitis, alveolar pylori and uterine fistula, cervical erosion, and trichomoniasis vaginitis (2% tincture). Write with medicine It is also used for high blood pressure and heart disease. Mixing pollen with nicotinic acid is used as a symptomatic medicine for inoperable stomach cancer. If you use this medicine, symptoms of intoxication, indigestion, burping, nausea are reduced, the food tastes better, and sleep is good.

Plantago asiatica L. (P.major L. var.asiatica) is another name also known as giljanggu, baejangjang, and cut the bottom of the leaves when they bloom.

The main components of the leaves are the iridoid glycosides of aquabin C ₁₅ H ₂₄ O ₉ , catalpol and flavonoids flantaginine (scutellalein-7-glucoside) and homoplantaginine (hispitolin-7glucoside). have. There is planttagin (5,6,4-trimethylscooterlane-7-glucoside) but it is not clear. Only apigenin. Luteolin, nefetin, 6-oxyluteolin glycosides. The leaves also contain palmitic acid esters of ursolic acid, gentriacontan C ₂₃ H ₄₈ , β-sitosterol, stigmasterol and β-sitosterol. There are also enzymes (emulsin and inverotene), carotene and ascorbic acid. Seeds contain acubin and many mucus.

Partial water decomposition of the mucus resulted in i) O-β-D-xyclopyranosyl- (1 → 2) -D-xylopyranosyl] as a disaccharide, ii) [O-β-D-xylpyranonosyl]. -(1 → 4) -D-xyclopyranose], iii) [(-β-D-glucopyranosyl-uronic acid- (1 → 5) -L-arabinopyranose]]. There are also plantenol acid (plantagoic acid), succinic acid, choline, adenine, vitamins A and B ₁ .

In addition, the outpost has a polysaccharide released in water, the polysaccharide has up to 28% of the ash and only about half is removed by electrodialysis. If refined for a long time, the ash reaches 0.4 ~ 0.5%. Polysaccharides consisted of 80-82% pectinic acid, 5-6% galactoaraban and 4-5% galactan. When pectin acid is hydrolyzed, galacturonic acid is 78 ~ 83%, galactose, arabinose and rhamnose. Small amounts of glucose, xylose and three other sugars are produced. That is, the polysaccharide consists of all nine sugars and minerals. Mineral-free polysaccharides contain 66-68% anhydrous galacturonic acid. Hydrolysis of this leads to galacturonic acid.

According to other data, the relative content of polysaccharides of rhamnose, arabinose, galactose, xylose, glucose and mannose is 6: 6: 3.5: 2.5: 1: 1. That is, pectin mainly contains galacturonic acid. In comparison with P.major, which grows plantain in Europe from the standpoint of chemical classification, the plantain has one more iridoid glycoside and 6-oxyluteolin glycoside. The content of polysaccharides varies between 8 and 19% depending on the growing season.

It is the highest when the leaves start to grow gradually in spring and the flower beds begin to emerge. When the fruit is ripe and the flower stalk dries, its content is lowest. Considering the productivity of raw materials, it is better to collect from the beginning of June to the end of June, from the time when the flower buds sprout to the flowers.

In effect, outposts and planttagins act on the center of the hob in animal experiments, slowing and deepening the hob. It also increases the secretion of mucous membranes, increasing the secretion of bronchial mucosa and digestive juices. Seed mucus is a relaxing and heat-lowering effect. The antitussive expectoration of plantain is different from saponin with hemolytic action and irritation to mucous membranes. It is good for children's cough medicine because it has no hemolysis and no side effects. Plantain also has a peeing action. In addition to increasing water excretion, it also promotes excretion of urea, sodium chloride and uric acid. Polysaccharides are anti-inflammatory and epithelial.

Outpost extract has anti-inflammatory and epithelialization effects on small wounds in animal experiments. Polysaccharides isolated from outposts are less toxic. Polysaccharides in rats 1 to 3g / kg, dogs to 2 ~ 5g / kg for 14 days, there is no poisoning effect. Polysaccharides inhibit gastric ulcer formation in rats by butadione. Feeding dogs also increases the secretion of gastric juice by 2.5 times and increases the free acidity and total acidity of gastric juice by 20-30%. However, it does not affect the protein lytic activity of gastric juice. Polysaccharides also slow the movement of matter three to four times through the stomach. The hardening of polysaccharides against isolated intestines in white rats is also seen in 1: 10,000 fluids.

In this way, polysaccharides have a hardening effect, anti-inflammatory action, and promote epithelialization, making it a good treatment for ulcers. Splitting minerals in polysaccharides does not have this effect. Therefore, it is considered that the polysaccharide combined with the inorganic material is a biologically active component. Polysaccharides have been shown to have good therapeutic effects in clinical trials. If a stomach duodenal ulcer patient eats 0.5-1 g at a time three times a day, pain disappears after 5-7 days, and ulcer symptoms disappear after 15-20 days, and the acidity of gastric juice is normal. The functional feature of polysaccharides is to lower the acidity of the acid and increase the acidity to normalize the secretion of gastric juice. In particular, patients with normal or low acidity of gastric juice have good therapeutic effect.

Applications include polysaccharides or juice from outposts for duodenal ulcers and chronic gastritis with or without acidity in gastric juice. Outpost decoction is also effective for nephropathy.

In motion therapy, outposts are used for gastrointestinal disease, other arteriosclerosis, and diabetes. Mr. Moon drinks from eye diseases and nervous system diseases.

Each herbal medicine that works with the above ingredients and effects should be shaded without sunlight in drying after collection, and if dried in sunny sunlight, the active ingredients contained in each dry matter will be destroyed or By evaporation, the effect is lowered or it is difficult to obtain as much extract as desired.

In addition, the degree of drying is a state in which the moisture is almost evaporated on the surface of each dried product, and in the case of the blade of grass, it is preferable to dry it until the tip is slightly dried. The degree of drying is not very important in extracting each dry matter, but the amount of solvent added in the following process is determined by the weight of each dried herb, and the more appropriate the drying, the less the amount of solvent used. It is preferable to appropriately set the drying step.

The amount of solvent added to each herbal medicine dried as described above is 100 g of each herbal medicine, water, ethanol, methanol, isopropyl alcohol, lower alcohols such as n-butanol, esters such as ethyl acetate, ketones such as cyclo-butanol, etc. It is preferable to mix about 1.5 to 2.5 L of a solvent in which one or two or more of solvents such as cyclopentane, n-hexane, chloroform and acetone are mixed.

In heating the herbal medicine, heating at atmospheric pressure in a mantle provided with a reflux condenser is preferably performed at atmospheric pressure for about 1-5 hours. If the atmospheric pressure is lowered below atmospheric pressure, the heating time can be shortened. It can also reduce heating time drastically.

What is necessary is just to adjust heating temperature suitably in consideration of the boiling point of the solvent used. In general, heating at atmospheric pressure for 1-5 hours may cause the components of the herb to dissolve. However, depending on the circumstances, the heating time can be shortened or extended.

When the heating is completed as described above, the extracts in the form of residues are suspended in the upper layer, the lower layer is mixed with the extract (extract) corresponding to the extract of the extract and the solvent is in the liquid phase, the extract of the residues in the upper layer The extracts remaining in the lower layer are filtered through a filter to obtain an extract and a solvent-only extract.

Then, the extract is evaporated at 40-60 ° C. at about 0.005-0.1 atmospheres to obtain an extract. At this time, if the evaporation temperature is increased to 60 ° C. or higher, there is a risk of causing chemical change in the extract or exiting under reduced pressure, and when the temperature is 40 ° C. or lower, there is a problem that it takes too much time for evaporation.

The amount of the extract obtained in the above process can be obtained as the solvent having a greater polarity (polarity). The amount of extract of each dry matter is somewhat different depending on the producing region and the harvesting time of each dry matter. When extracts are obtained using a mixture of several solvents, an amount similar to that of using each solvent can be obtained.

For example, the yield of the extract obtained by adding l l of water: ethanol ratio in the ratio of 90: 10 to 10: 90 to each 100 g dried in the shade in the same manner as above is used as water or ethanol as a solvent. Similar results are obtained.

The extract mixing ratio of each herbal medicine obtained by the above method is 5-40% by weight of wild buckwheat, 5-20% by weight of algae grass, 5-30% by weight of honeysuckle, 0.5-10% by weight of licorice, and 5-40% by weight of vulgaris. , Dandelion 5-20% by weight, whitening 0.5-10% by weight, marigold 0.5-10% by weight, chajeoncho 5-20% by weight.

If the extract mixing ratio of the herbal medicine is less than or exceeds that, it is preferable to maintain the above mixing ratio because there is a problem that the action and efficacy of each of the herbal medicines described above are not achieved in the desired value.

It is a step of containing 5 to 70% of an extract mixture obtained by the above method in a conventional food composition to complete the food. Since there are various types of foods and different ingredients according to each dosage form, there are some concerns about the ingredients in containing extracts, but many experiments have not found such a problem.

If the extract in the food extract (extract) is less than 5% by weight, the effect is insignificant, and if it exceeds 70% by weight, the effect is remarkable, so preferably 5%-70% by weight. Although the content rate of each said component can be arbitrarily selected over a wide range in principle, it is 5-70 weight% as solid content.

The mixture containing the above ingredients may be used as the functional food of the present invention as it is, but may be mixed with conventional excipients (lactose, corn starch, microcrystalline, cellulose, magnesium stearate, etc.) as necessary, It can be formulated into a dosage form commonly used in internal medicine such as granules, tablets, capsules and the like.

In addition, it may be used by mixing a certain amount of processed foods such as confectionery, bread, candy, gum, ice cream or beverage, cosmetics and additives of tobacco, and animal feed, or may be combined with medicine, herbal medicine and the like.

Hereinafter, the present invention will be described based on Examples.

(Example 1)

Weak buckwheat, algae grass, honeysuckle, licorice (national road), marshmallow, dandelion, white zirconia, marigold and chajeoncho, and dried in the shade, and then mixed by adding 2 liters per 100 g of the dried herbal medicine, The mixture was heated under atmospheric pressure for 2 hours in a mantle equipped with a reflux condenser. The residue at the top of the heated mixture was removed and the liquid residue at the bottom was filtered to obtain an extract (solvent and mixed extract dissolved therein), and the extract was extracted at 0.008 atmospheres (5 mmHg) and 50 ° C. The solvent contained in the extract was evaporated to finally obtain an extract. The amount of extract obtained for each solvent is shown in Table 1 below.

         TABLE 1

Kind of solvent Yield (%) Kind of solvent Yield (%) water 10 Acetone 3 ethanol 8 chloroform 4 Methanol 8 Cyclo-butanol 4 Isopropyl Alcohol 6 Cyclo-pentane 2 n-butanol 6 n-hexane 2 Ethyl acetate 7

The components of the extract extracted using the various solvents are different in the amount, but the component analysis of each extract confirmed that there is no significant difference in the main components of all extracts. However, considering the high amount of extract (high yield) and harmless lighting to the human body, it has been found to be preferable to extract using water or ethanol as a solvent.

The herbal extract prepared by the above method (hereinafter referred to as "the present invention") was applied to rats to determine the concentration of Nicotine in the blood of the rats, and the measurement results are shown in Tables 2 to 8.

1) Test subject

ICR Mouse of Wister strain male rats (6 weeks old)

2) Test environment

Animals were housed in 5 wire cages in an animal room set at room temperature 24 ± 1 ° C., humidity 55 ± 5%, ventilation number 12 times / hour, lighting time 12 hours / day (morning time, 8 o'clock, etc.). The feed allowed the free intake of solid feed with water.

3) Administration method

Adapted to the test environment for 2 weeks and animals were tested at 8 weeks of age.

Test substance was orally administered by mixing the present invention with a solid feed.

The present invention was mixed with 0.5 ml / solid solid feed and orally administered to the body as free food with water.

4) administration time

Administration was performed at 2 pm and the period was 7 days.

At the end of dosing and at the end of the test, 1 ml of blood was drawn from the heart as a sample for nicotine measurement.

5) Observation Method

Dosing days were observed immediately after administration and in the evening, and the morning and evening thereafter.

Observation was carefully conducted from outside the breeder.

6) Test result of nicotine concentration in blood

Blood was adjusted to ph9 with dilute ammonia water. Subsequently, the resultant was kept in EXTRELUT COLUMN. (Manufactured by Merck Co., Ltd.) for 15 minutes, eluted with 15 ml of ethyl acetate, and the eluted acetate was distilled off under reduced pressure.

For analysis, use gas chromatography (HP 5890 SERIESπ, FID attached). COLUMN used a glass column 2 m long and 3 mm in diameter filled with 2% Tharmon 1000 + 1% KOH Chromosorb WAM (8 / 100Mesh).

The COLUMN temperature was 100 ° C., the carrier gas was N 2, and the flow rate was 60 ml / min.

TABLE 2

Result after 1 day administration of HAT (Herb Anti-Toxin) substance of the present invention (Nicotine concentration 30mg / kg / 10ml intraperitoneally) (Hereinafter, "detoxification agent" shall use the present invention)

TABLE 3

Result after 2 days administration of HAT substance (Nicotine concentration 30mg / kg / 10ml intraperitoneally)

TABLE 4

Result after 3 days administration of HAT substance (Nicotine concentration 30mg / kg / 10ml intraperitoneally)

TABLE 5

Result after 4 days administration of HAT substance (Nicotine concentration 30mg / kg / 10ml intraperitoneally)

Table 6

Result after 5 days of HAT substance (Nicotine concentration 30mg / kg / 10ml intraperitoneally)

Table 7

Result after 6 days of HAT substance (Nicotine concentration 30mg / kg / 10ml intraperitoneally)

Table 8

Result after 7 days of administration of HAT substance (Nicotine concentration 30mg / kg / 10ml intraperitoneally)

7) autopsy

At the end of dosing, there was no gross abnormality in each individual when recovered from necropsy, but gross abnormalities were found in each individual at death.

In addition, the herbal extract prepared by the above method was applied to rats to measure the urine Nicotine concentration of the rats and the measurement results are shown in Tables 9 to 16 below.

1) Test subject

ICR Mouse of Wister strain male rats (6 weeks old)

2) Test environment

Five animals were housed in a wire cage in an animal room set at room temperature 24 ± 1 ° C., humidity 55 ± 5%, ventilation number 12 times / hour, lighting time 12 hours / day (lighted up in the morning, lighted out at 8 o'clock). Was allowed to consume solid feed freely with water.

3) Administration method

Adapted to the test environment for 2 weeks and animals were tested at 8 weeks of age.

Test substance was orally administered by mixing the present invention with a solid feed.

The present invention was mixed with 0.5 ml / solid solid feed and orally administered to the body as free food with water.

4) Dosing time

Administration was performed at 2 pm and the period was 7 days. At the end of dosing and at the end of the test, 1 ml of blood was collected from the bladder as a sample for nicotine concentration measurement.

5) Observation Method

Dosing days were observed immediately after administration and in the evening, and the morning and evening thereafter.

Observation was carefully conducted from outside the breeder.

6) Test result of nicotine concentration in urine

Urine was adjusted to pH 9 with dilute ammonia water. Then EXTRELUT COLUMN. (Merck Co., Ltd.) was maintained for 15 minutes, eluted with 15 ml of ethyl acetate, the eluted acetate was distilled off under reduced pressure, 100 µl of ethyl acetate was added to the resulting residue to dissolve and used as an assay sample.

For analysis, use gas chromatography (HP 5890 SERIESΠ with FID).

COLUMN used a glass column 2 m long and 3 mm in diameter filled with 2% Tharmon 1000 + 1% KOH Chromosorb WAM (8 / 100Mesh).

The COLUMN temperature was 100 ° C., the carrier gas was N 2, and the flow rate was 60 ml / min.

Table 9

Result after 1 day administration of HAT substance (Nicotine concentration 30mg / kg / 10ml intraperitoneally)

Table 10

 Result after 2 days administration of HAT substance (Nicotine concentration 30mg / kg / 10ml intraperitoneally)

Table 11

 Result after 3 days administration of HAT substance (Nicotine concentration 30mg / kg / 10ml intraperitoneally)

Table 12

 Result after 4 days administration of HAT substance (Nicotine concentration 30mg / kg / 10ml intraperitoneally)

Table 13

 Result after 5 days of HAT substance (Nicotine concentration 30mg / kg / 10ml intraperitoneally)

Table 14

 Result after 5 days of HAT substance (Nicotine concentration 30mg / kg / 10ml intraperitoneally)

Table 15

Result after 6 days of HAT substance (Nicotine concentration 30mg / kg / 10ml intraperitoneally)

Table 16

Result after 7 days of administration of HAT substance (Nicotine concentration 30mg / kg / 10ml

Paralysis symptoms Hyperactivity start time Hyperactivity End Time Death time Nicotine concentration in blood (㎍ / ㎖) G1 One 27 ' 2'10 ' 5'50 ' recovery 0.017 2 36 ' 2'44 ' 6'10 ' recovery 0.014 3 43 ' 3'25 ' 6'51 ' recovery 0.017 4 43 ' 3'50 ' 5'56 ' recovery 0.016 5 33 ' 3'52 ' 6'35 ' recovery 0.015 G2 One 22 ' 4'42 ' 6'45 ' 31'18 ' 1.011 2 26 ' 4'46 ' 6'35 ' recovery 0.010 3 20 ' 5'40 ' 7'25 ' recovery 0.012 4 24 ' 5'47 ' 7'20 ' recovery 0.023 5 23 ' 4'46 ' 6'47 ' recovery 0.012 G3 One 23 ' 35 ' 56 ' 1'33 ' 12.178 2 33 ' 45 ' 1'15 ' 1'35 ' 12.183 3 29 ' 31 ' 1'20 ' 1'50 ' 12.987 4 25 ' 54 ' 1'35 ' 1'57 ' 12.969 5 22 ' 51 ' 1'50 ' 2'10 ' 11.719 G4 One 33 ' 2'50 ' 4'20 ' 6'15 ' 4.019 2 25 ' 2'40 ' 4'50 ' 7'18 ' 3.679 3 24 ' 2'45 ' 4'47 ' 6'45 ' 4.095 4 21 ' 2'37 ' 5'10 ' 6'25 ' 4.074 5 33 ' 2'35 ' 4'15 ' 6'54 ' 4.117

G1: Nicotine administration after pretreatment of this invention.

G2: The present invention was administered after Nicotine administration after pretreatment of the present invention.

G3: control Nicotine.

G4: Administration of the invention after administration of the control Nicotine.

      The test population was tested five dogs in each group

7) autopsy

At the end of dosing, there was no gross abnormality in each individual when recovered from necropsy, but gross abnormalities were found in each individual at death.

In addition, the herbal extract prepared by the above method was applied to the rat to measure the carbon monoxide concentration in the blood of the rat and the measurement results are shown in Table 17 below.

1) Test subject

ICR Mouse of Wister strain male rats (6 weeks old)

2) Test environment

Animals were housed in 5 wire cages in an animal room set at room temperature 24 ± 1 ° C., humidity 55 ± 5%, ventilation times 12 times / hour, lighting time 12 hours / day (lighted up in the morning, lighted out at 8 o'clock). The feed allowed the free intake of solid feed with water.

3) Administration method

Adapted to the test environment for 2 weeks and tested at 8 weeks of age.

Test substance was orally administered by mixing the present invention with a solid feed.

The present invention was mixed with 0.5 ml / solid solid feed and orally administered to the body as free food with water.

4) C0 expose method

The day after the end of the administration, each animal was housed in an exposure chamber (manufactured by Sugiyamage, Japan), and a mixed gas of 21% O ₂ and 100 ppm CO was introduced into the pump and aspirated for 5 minutes. The concentration in the chapter was examined with a carbon monoxide meter (COM-4, manufactured by Komei Rikagaku Kogyo, Japan).

5) Measurement of CO-Hb Concentration in Blood

Immediately after the end of the exposure, blood was drawn from the heart, 0.5 ml of blood was placed in a 5 ml reaction vial, and a drop of octyl alcohol and 0.25 ml of saturated aqueous solution of potassium ferricyanate were added. The reaction solution was capped and shaken for 5 minutes, followed by gas phase. Was used as analytical sample.

The analysis was performed using gas chromatography (HP 5890 SERIESΠ, with TCD).

COLUMN used a glass column 2m in length and 3mm in diameter filled with molecular sieve 5A (3 / 60Mesh).

The COLUMN temperature was 60 ° C, the carrier gas was H2, and the flow rate was 50 ml / min.

6) Results

The results of measuring the CO concentration in the blood after the test are shown in Table 17 below.

Table 17

Results after 7 days administration of the present invention

CO-Hb concentration in blood (%) G1 One 53.8 2 52.9 3 50.3 4 52.8 5 53.5 G2 One 53.0 2 52.8 3 53.5 4 52.9 5 53.0 G3 One 69.3 2 70.2 3 69.1 4 68.5 5 68.9 G4 One 61.5 2 60.8 3 62.9 4 62.1 5 61.8

7) autopsy

At the end of the autopsy, no gross abnormalities were found in each individual in each group.

In addition, the herbal extract prepared by the above method was applied to the rats were tested for the rat Tar, and the test results are shown in Table 18 below.

1) Test subject

ICR Mouse of Wister strain male rats (6 weeks old)

2) Test environment

Five animals were housed in a wire cage in an animal room set at room temperature 24 ± 1 ° C., humidity 55 ± 5%, ventilation number 12 times / hour, lighting time 12 hours / day (morning time, 8 o'clock at night). Was allowed to consume solid feed freely with water.

3) Administration method

Adapted to the test environment for 2 weeks and tested at 8 weeks of age.

Test substance was orally administered by mixing the present invention with a solid feed.

Dose concentration was 25g body weight and the present invention was mixed with 0.5g / horse solid feed and Tar with water was administered into the stomach using a Stomach tube.

4) Observation Method

Dosing days were observed immediately after administration and in the evening, and the morning and evening thereafter. Observation was carefully conducted from outside the breeder.

5) Results

The results of measuring Tar after the test are shown in Table 18 below.

Table 18

Result after administration of the present invention (Tar concentration 30mg / kg / 10ml intraperitoneally)

1 day 2 days 3 days 4 days 5 days 6 days 7 days G1 One Survival 2 survival survival survival survival survival survival 2 Survival 3 survival survival survival survival survival survival 3 Survival 4 survival survival survival survival Dead Dead 4 Survival 5 survival survival survival survival survival survival 5 Survival 1 survival survival survival survival survival survival G2 One Survival 2 survival survival survival survival Dead  Dead 2 Survival 3 survival  Dead Dead Dead Dead Dead 3 Survival 4 survival survival survival survival survival survival 4 Survival 5 survival survival  Dead Dead Dead Dead 5 survival survival survival survival survival Dead Dead

Note: G1: Tar administration after pretreatment by mixing the present invention in a general feed.

           G2: Tar administration while the control diet.

           The test population was tested five dogs in each group.

In addition, the herbal extract prepared by the above method was applied to the rats to test the antioxidant power of the rats and the test results are shown in Table 19 and Table 20.

1) Test subject

Antioxidant activity was tested by Kiharu et al. (1990) using a solution containing 2 mg of linoleic acid in 1 mL of distilled water, a solution of 10 mg of Tween-20 in 1 mL of distilled water, and 0.2M Potassium phosphate (pH 7.4) aerated for 1 hour. ) Mixture was prepared by adding the invention to 1.0 ml. The mixture was reacted at 37 ° C for 24 hours, taking 0.1 ml of the reaction solution at 3 hour intervals, adding 9.7 ml of 75% Etanol, 0.1 ml of 30% Ammonium thiocyanate and 0.1 ml of 0.02 M ferrous ammonium sulfate-3.5% hydrochloric acid. After the addition, the absorbance was measured at 500 nm after 3 minutes.

2) results

The antioxidant power measurement results of the present invention are shown in Table 1 and Table 2. As a control, a synthetic antioxidant BHT (dibutyl hydroxy toluen) and a natural antioxidant α-Tocopherol were used. Table. As shown in Fig. 1, B showed the highest antioxidative activity, more antioxidant activity than α-tocopherol, slightly lower antioxidative activity than BHT, and A-G and high antioxidative activity.

And the antioxidant power was measured using the present invention was found to show a high difference with the control.

Table 19

Antioxidant Test Result 1

Table 20

Antioxidant Result 2

And, the test for increasing the surface ductility is as follows.

Splenic cell culture

1) Test subject

Spleens from three-week-old ICR mice were washed with physiological saline to separate splenocytes from complete RPMI 1640 media. Separate splenocytes into 96well at 2 x 105 cells / ml and incubate with stimulators such as Con A and LPS. Treat HAT at different concentrations and incubate for 2 days at 37 ℃ and 5% CO2 incubator. 20 μl / well was used to measure absorbance with a micro plate reder.

* Concentration of the invention: 20, 50, 100, 200 ug / ml

* All experiments were performed in a clean bench, and all samples including media were filtered (22 μm) and treated to cells.

* micro plate reder: measured at measurment 570 nm, referance 600 nm

** Alamar Blue assay: Alamar blue dye is a non-toxic cytotoxity assay that uses metabolic properties of cells to turn blue. When the OD value measured by the micro plate reder is low, the cell proliferation is estimated to be reduced.

2) Test result

After two days of incubation with ControlA as a stimulus, alamar blue was added, and the results of the present invention after 32 hours were shown in Table 21.

Table 21

Average Standard error nomal 0.05 0.01 control 0.09 0.01 The present invention 200 0.14 0.01 The present invention 100 0.13 0.01 Present invention 50 0.11 0.01 25th invention 0.08 0.01
On the other hand, the present invention is a mixture of medicinal herbs, dysentery, honeysuckle, licorice, marshmallow, dandelion, white tea, marigold, chajeoncho is mixed to detoxify the dioxin.

The functional dietary supplement of the present invention as described above has the effect of lowering the amount of nicotine in the blood and the effect of releasing the amount of nicotine in the urine and the exposure to carbon monoxide when the nicotine is administered to the human body at the same time. -Action to lower hemoglobin concentration. Therefore, the functional dietary supplement of the present invention reduces the harmful effects of tobacco smoking, and reduces the amount of nicotine in the blood, thereby removing various harmful substances in the human body caused by tobacco smoking.

In addition, the functional dietary supplement of the present invention exhibits an effect on high antioxidant power and total cholesterol, blood fat, lipid peroxidation, and has the effect of increasing the immunity to increase the body's resistance to disease from the outside.

Moreover, the functional food of the present invention is consumed as a food or formulated food, so there is no need to interrupt smoking habits, use other items or add extra actions when smoking. Therefore, the effect can be easily achieved without affecting the smoking habit. It is also nontoxic and can be taken without disinfection at all times.

Claims (6)

A process of collecting and drying weak wheat grass, dendritic grass, honeysuckle, licorice, marshmallow, dandelion, white zirconia, marigold and chajeoncho; A step of heating the dried herbal medicines into each heating container together with a solvent obtained by mixing any one or two or more of water, ethanol, methanol, isopropyl alcohol, n-hexane, chloroform and acetone; Filtering each extract obtained by heating and concentrating the filtered extract under reduced pressure and then drying; The extract of each herbal medicine obtained by drying is 5-40% by weight of wild buckwheat, 5-20% by weight of algae grass, 5-30% by weight of honeysuckle, 0.5-10% by weight of licorice, 5-40% by weight of dandelion, dandelion 5 Functional dietary supplement manufacturing method characterized in that it was mixed in a ratio of ~ 20% by weight, 0.5-10% by weight, marigold 0.5-10% by weight, 5-20% by weight of chajeoncho. delete The method according to claim 1, wherein the amount of the solvent added to the herbal medicine is 5% to 50 times as much as the solvent in the herbal medicine. The method according to claim 1, wherein the heating temperature and time of the solvent added to the herbal medicine are 0.5 to 5 hours at 25 ℃ ~ 100 ℃. Functional health food to remove harmful components in the body prepared by the method of claim 1. The functional dietary supplement according to claim 5, wherein the herbal extract is prepared in the form of powder, granules, tablets or capsules.