KR100480970B1 - 당귀 추출물을 유효성분으로 하는 다이옥신 유사물질에대한 길항성 조성물 - Google Patents
당귀 추출물을 유효성분으로 하는 다이옥신 유사물질에대한 길항성 조성물 Download PDFInfo
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- KR100480970B1 KR100480970B1 KR10-2001-0068919A KR20010068919A KR100480970B1 KR 100480970 B1 KR100480970 B1 KR 100480970B1 KR 20010068919 A KR20010068919 A KR 20010068919A KR 100480970 B1 KR100480970 B1 KR 100480970B1
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- dioxin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/334—Foods, ingredients or supplements having a functional effect on health treating the effects of consuming alcohol, narcotics or other addictive behavior, e.g. treating hangover or reducing blood alcohol levels
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
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- Biotechnology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
구 분 | 실험동물수 | 체중(g) | 절대적 기관 무게 (㎎) | 상대적 기관 무게3) (㎎) | ||
좌측 고환 | 우측 고환 | 좌측 고환 | 우측 고환 | |||
무처리군 | 6 | 446.0 ±54.51 | 783.02±150.1 | 759.70±146.39 | 173.28±45.22 | 168.70±40.80 |
TCDD 처리군 | 6 | 393.2±39.35 | 630.04±133.0 | 633.80±113.06 | 156.42±31.20 | 157.59±20.80 |
추출물 처리군 | 6 | 458.0±60.43 | 872.28±102.2 | 899.23±122.40 | 194.29±41.97 | 199.60±39.41 |
추출물 + TCDD 전-처리군1) | 6 | 456.5±56.62 | 826.53±188.4 | 797.63±178.37 | 181.30±49.90 | 175.09±49.13 |
추출물 + TCDD 후-처리군2) | 6 | 424.0±57.80 | 838.20±191.6 | 887.35±211.57 | 196.11±25.24 | 210.87±55.48 |
1) TCDD 처리후 7일째부터 추출물 음수 투여군 2) 시험 개시일로부터 7일째에 TCDD 처리한 군 3) 실험 래트의 체중(100 g 기준)과 비교한 상대적 무게(환산값) |
Claims (6)
- 당귀 추출물을 유효성분으로 하고, 다이옥신 유사물질의 XRE (Xenobiotic response element) 관련 신호전달 체계에 대한 작용을 방해하여 다이옥신 유사물질의 세포내 작용을 억제하는 다이옥신 유사물질에 대한 길항성 조성물.
- 삭제
- 당귀 추출물을 유효 성분으로 포함하는 다이옥신 유사물질에 대한 길항성 건강 식품 조성물.
- 제 1 항 또는 제 3 항에 있어서, 상기 다이옥신 유사물질은 PCDD (폴리염소화 디벤조-p-다이옥신), PCDF (폴리염소화 디벤조퓨란) 및 PCB (폴리염소화 비페닐)로 구성된 군으로부터 선택됨을 특징으로 하는 조성물.
- 제 4 항에 있어서, 상기 다이옥신 유사물질은 PCDD (폴리염소화 디벤조-p-다이옥신)인 것을 특징으로 하는 조성물.
- 제 5 항에 있어서, 상기 PCDD (폴리염소화 디벤조-p-다이옥신)는 TCDD (2,3,7,8-테트라클로로디벤조-p-다이옥신)인 것을 특징으로 하는 조성물.
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KR1020000065655 | 2000-11-06 | ||
KR20000065655 | 2000-11-06 |
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KR20020035467A KR20020035467A (ko) | 2002-05-11 |
KR100480970B1 true KR100480970B1 (ko) | 2005-05-17 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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KR20160096883A (ko) | 2015-02-06 | 2016-08-17 | 경성대학교 산학협력단 | 고지혈증 치료에 유용한 약학 조성물 |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100480971B1 (ko) * | 2001-03-24 | 2005-05-17 | (주)내츄럴엔도텍 | 정향 추출물을 유효성분으로 하는 다이옥신 유사물질에대한 길항성 조성물 |
KR20030004012A (ko) * | 2001-03-24 | 2003-01-14 | 주식회사 메덱스바이오 | 선씀바귀 추출물을 유효성분으로 하는 다이옥신유사물질에 대한 길항성 조성물 |
KR20030003669A (ko) * | 2001-03-24 | 2003-01-10 | 주식회사 메덱스바이오 | 강활 추출물을 유효성분으로 하는 다이옥신 유사물질에대한 길항성 조성물 |
KR100480972B1 (ko) * | 2001-03-24 | 2005-05-06 | (주)내츄럴엔도텍 | 초피나무 추출물을 유효성분으로 하는 다이옥신유사물질에 대한 길항성 조성물 |
KR100480973B1 (ko) * | 2001-03-24 | 2005-05-17 | (주)내츄럴엔도텍 | 댕댕이덩굴 추출물을 유효성분으로 하는 다이옥신유사물질에 대한 길항성 조성물 |
KR20030003670A (ko) * | 2001-03-24 | 2003-01-10 | 주식회사 메덱스바이오 | 백질려 추출물을 유효성분으로 하는 다이옥신 유사물질에대한 길항성 조성물 |
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KR920014718A (ko) * | 1991-01-22 | 1992-08-25 | 김천식 | 도토리를 이용한 중금속 제거제의 제조방법 |
KR19980045819A (ko) * | 1996-12-11 | 1998-09-15 | 강익중 | 분리막 장치에 의한 한약내 유해 중금속제거 방법 |
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KR830010187A (ko) * | 1981-07-21 | 1983-12-26 | 로버트 제이. 한스 | 폴리아미드 함유 작용유체 조성물 |
KR920014718A (ko) * | 1991-01-22 | 1992-08-25 | 김천식 | 도토리를 이용한 중금속 제거제의 제조방법 |
KR19980045819A (ko) * | 1996-12-11 | 1998-09-15 | 강익중 | 분리막 장치에 의한 한약내 유해 중금속제거 방법 |
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KR20160096883A (ko) | 2015-02-06 | 2016-08-17 | 경성대학교 산학협력단 | 고지혈증 치료에 유용한 약학 조성물 |
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