KR100456505B1 - Mild liquid detergent composition - Google Patents

Abstract

The present invention relates to a liquid face wash composition comprising N-acyl glutamate of formula (I), cocamidopropylbetaine of formula (II), and a fatty acid soap of formula (III). It is about.

Where

M ₁ represents an alkali metal cation, alkaline earth metal cation, ammonium, or the like which is a cosmetically acceptable counter ion,

COR ₁ represents C ₆ -C ₃₄ acyl,

R ₂ is an alkyl having 8 to 20 carbon atoms and is a fatty acid derived from animal oils such as Uji and pork and vegetable oils such as palm oil and palm oil,

M ₂ represents sodium and / or potassium.

Description

Mild liquid cleanser composition

The present invention relates to a face wash composition. In particular, the present invention relates to a liquid face wash composition comprising N-acyl glutamate as a main component and containing 8 to 20 carbon-based fatty acid soaps and cocamidopropyl betaine. The liquid cleanser composition of the present invention is safe for human body and the environment.

[Technical Field to which the Invention belongs and Prior Art in the Field]

In general, the main function of the face wash is a cleaning function. The face wash is required to remove not only the waste of the skin but also make-up, so it requires excellent cleaning power. In addition to the cleansing function, the face wash requires various functions such as sufficient foaming power, excellent feeling of use, moisturizing and nourishing the skin. Among these various functions, the cleaning function is the most important function, and in particular, it should play a role of removing cosmetics from the skin. The application of cosmetics on human skin (particularly the face) is used by women as a means of improving aesthetics and protecting the skin from external stimuli (sunshine, wind, boiling). Cosmetics applied to the skin should be removed after a certain amount of time disappears. Cosmetics, especially cosmetics such as lipsticks and mascara, which are mainly composed of waxes, are strongly adhered to the skin and may not be completely removed by normal washing or may irritate and damage sensitive skin due to strong cleaning power.

Therefore, the cleanser applied to the skin, especially the face, is a product that requires proper cleansing power and hypoallergenic skin.

The cleaning ingredient used in the face wash may be a general fatty acid soap using an alkali salt of a higher fatty acid as a base, a synthetic surfactant soap using a synthetic surfactant as a base, or a general fatty acid soap and a synthetic surfactant. Or it can be summarized as three types of complex soaps used as a mixture of auxiliary bases, fatty acid soaps, sodium or potassium salt of 8 to 20 carbon atoms, fatty acids are palm oil, palm oil, soybean oil, castor oil, olive oil, palm It is obtained from vegetable oils such as nuclear oil and animal fats such as tallow, lard and fish oil, and can be used alone or in combination. And, in the case of synthetic surfactant soap, sodium lauryl sulfonate, sodium salt of alkylbenzene sulfonate, sodium coco Any surfactant commonly used in soaps such as one isethionate can be used. In the case of the compound soap, the raw materials used in the general fatty acid soap and the synthetic surfactant soap may be mixed and used as a periodic agent or auxiliary base.

In the case of the present invention, by using a mixture of general fatty acid soap and synthetic surfactant, it was intended to satisfy the proper cleaning power, sufficient foaming power, excellent feeling and skin hypo-irritability.

Typically, soaps have been used as skin cleaners. Most soaps contain a mixture of soaps obtained from coconut fat and tallow. Other soluble soaps derived from lauryl acid soaps and coconut fats contribute to the foaming properties of the overall composition, while longer chain soaps obtained from tallow provide a structure. As a detergent, soap has the advantages of good foaming power, clean feeling, and low price, but has the disadvantage of giving skin irritation and feeling of dryness. Therefore, taking advantage of these soaps, a mixture of surfactants were used to compensate for the disadvantages.

Sulfates are currently used as surfactants. These compounds have been used as main surfactants in almost all cleaning agents because of their excellent cleaning power, abundant foaming power, and low price. However, recently, human toxicity, environmental safety, and the like tend to be a problem. Also widely used surfactants are phosphates. Despite its excellent detergency and low human toxicity, it has the disadvantages of environmental safety such as eutrophication. With increasing interest in human safety, the development of surfactants that satisfies the desired properties (cleaning power, foaming power, etc.) while reducing the toxicity of the surfactants has been actively progressed in recent years, and the use thereof is rapidly increasing. to be.

Surfactants known to be mild today include amino acid surfactants, polypeptide surfactants, amine oxide surfactants, betaine surfactants, sulfosuccinate surfactants, imidazoline surfactants, and phosphate surfactants. And alkyl saccharide surfactants, alkyl taurate surfactants, alkyl polyglycoside surfactants, and polyoxyethylene sorbitan fatty acid ester surfactants.

The present inventors used the cytotoxicity test method to evaluate the human safety of these surfactants, and carried out acute fish toxicity test as a means of evaluating the environmental safety, and measured the cleaning power test and bubble generation as part of the evaluation of the feeling. . From these experiments, it was found that it is preferable to use N-acyl glutamate as a main component of a mild liquid cleanser.

Attempts have been made to combine N-acyl glutamate with various surfactants to expect beneficial properties.

Japanese Patent Application No. 73119550 (AJINOMOTO) discloses that a detergent mainly composed of monosodium N-oleyl-L-glutamate and lecithin is superior in cleaning power to that containing no lecithin.

Japanese Patent Application No. 7119608 (KAO SOAP) describes a cleaning composition composed mainly of N-lauryl-L-glutamic acid monosodium salt and dimethyldodecylamine oxide.

Japanese Patent Application No. 771l7670 (KANEBO) describes a cleaning composition composed mainly of N-acyl glutamate, organic carboxylic acid and phosphoric acid, and has excellent foaming power, cleansing power, and hypoallergenic effect on skin.

European Patent Application No. 324575 (KAO) describes a cleaning composition composed mainly of nonionic surfactants, phosphate-based surfactants, N-acyl glutamate, isethionate and sulfosuccinate, and has excellent cleaning and hypoallergenic properties. I am characterized

As described above, many attempts have been made to produce a mild detergent that is hypoallergenic to the human body using N-acyl glutamate, but it is appropriate to use a mild surfactant N-acyl glutamate, an amphoteric surfactant, cocamidopropyl betaine and fatty acid soap. There has been no prior art for a gentle liquid cleansing composition that is excellent in cleansing, foaming, and usability in combination with safety for humans and the environment.

The present inventors have comparatively tested various physical properties such as cytotoxicity, fish toxicity, detergency, and foaming power against many surfactants known to be mild, and they contain N-acyl glutamate as a main component and cocamido as an amphoteric surfactant. The liquid face cleanser composition prepared by properly combining propyl betaine and fatty acid soap has excellent cleaning power and foaming ability, and is practically safe for human body, safe for the environment, and can be safely applied to people with sensitive skin. The present invention has been completed.

The present invention contains at least one N-acyl glutamate of the following general formula (I), at least one cocamidopropylbetaine of the following general formula (II), and at least one fatty acid soap of the following general formula (III). It relates to a liquid face wash composition characterized in that.

Where

M ₁ represents a cosmetically acceptable counter ion, preferably hydrogen, alkali metal cation, alkaline earth metal cation or ammonium, most preferably triethanolamine

COR _1, is acyl, preferably C ₆ -C ₃₄ acyl, more preferably C ₈ -C _l8 acyl, most preferably represents a C ₁₀ -C ₁₄ acyl,

R ₂ is an alkyl having 8 to 20 carbon atoms and is a fatty acid derived from animal oils such as tallow and pork and vegetable oils such as palm oil and palm oil.

M ₂ is sodium and / or potassium.

In the liquid face wash composition according to the present invention, the N-acyl glutamate of the general formula (I) is an anionic surfactant derived from an amino acid system. Lauryl-L-glutamate, monosodium N-cocoyl-L-glutamate, and the like.

N-acyl glutamate suitable for use in the composition according to the present invention is a commercially available material and includes the following materials.

(a) Acyl glutamate CT-12. Refers to monotriethanolamine N-cocoyl-L-glutamate and is present in a 30% aqueous solution.

(b) CMT-L: monotriethanolamine N-palm oil fatty acid-L glutamate, present in 30% aqueous solution.

In the liquid face wash composition according to the present invention, the amount of N-acyl glutamate of the general formula (I) is preferably 5 to 40% by weight, more preferably 10 to 30% by weight, most preferably 15 to 25% by weight. to be. If N-acyl glutamate is less than 5% by weight, the cleaning effect is insignificant, and in excess of 40% by weight, human toxicity may increase.

When N-acyl glutamate is used as the main component of liquid cleansers, it shows better human safety and environmental safety than many other mild surfactants.

In the liquid face wash composition according to the present invention, the cocamidopropyl betaine of the general formula (II) is an amphoteric surfactant derived from trimethylglycine. Cocamidopropylbetaine suitable for use in the present invention is a commercially available material, for example Sunbet-C which is present in 30% aqueous solution. Cocamido as a surfactant component present in the liquid face wash composition according to the present invention. The amount of propylbetaine is preferably 1 to 30% by weight, more preferably 3 to 20% by weight, most preferably 5 to l5% by weight. If the cocamidopropyl betaine is less than 1% by weight, the cleaning effect is weak, and if it is more than 30% by weight, human toxicity may increase.

In the liquid face wash composition according to the present invention, the higher fatty acids of the fatty acid soap of general formula (III) include lauryl acid, myristyl acid, stearyl acid, and the like, which are commercially available materials. It is preferable to use sodium hydroxide or potassium hydroxide as a neutralizing agent of these higher fatty acids. The amount of the fatty acid soap present in the liquid face wash composition according to the present invention is preferably 1 to l5% by weight, more preferably 1 to 10%. % By weight, most preferably 1 to 5% by weight. If the fatty acid soap is less than 1% by weight, the cleaning effect is weak, and if it is more than l5% by weight, human toxicity may increase.

The liquid facial cleanser composition according to the present invention may optionally include other components within the range of not impairing its mild properties in order to improve the physicochemical properties, properties, safety, etc. of the composition. Can be mentioned.

(a) Cosurfactants: One or more additional surfactants selected from anionic surfactants, nonionic surfactants, amphoteric surfactants and zwitterionic surfactants derived from natural ingredients without compromising the beneficial features of the present invention. It is desirable to have characteristics.

(b) Conditioning agents: Conditioning agents such as polyquaternium, silicone oil, derivatives of hydroxypropyl guar gum, and preferably having properties derived from natural components without compromising the beneficial features of the present invention.

(C) Moisturizers. Examples are glycerin and propylene glycol.

(d) Preservatives, for example ethanol, benzoic acid, ketone CG and the like.

The liquid facial cleanser composition of the present invention is present in the liquid phase in a lid container such as a bottle, or in a pump container or a tube container.

Although an Example and an Example are given and this invention is demonstrated to the following, these Examples do not limit the technical scope of this invention.

Experimental Example

1. Experiment of selecting mild surfactant.

Surfactant among the components of the liquid face wash composition according to the present invention are the mild components that have been tested as follows.

(a) Cytotoxicity test

As an in vivo test method for estimating human safety, it is an in vitro test method for evaluating safety at the cellular level. After culturing 3T3 fibroblasts on the plate, the samples to be tested were inoculated in concentrations (1,000, 800, 600, 400, 200, 100, 80, 60, 40,20 (µg / ml)) and then incubated after one day Find the concentration. The higher the semi-numerical concentration, the lower the irritant The experimental results showed that the half-density concentration of N-acyl glutamate was about 10 times higher than that of sulfates. The results are shown in <Table 1>.

(b) Acute fish toxicity test

One group of 10 healthy fishes fasted for one day was placed in a group containing a constant concentration (300 ppm) of surfactant and observed for lethal time. An air injector and a circulating filter were installed in the tank. No feed was added during the day. The amount of experimental water was 1 L or more with respect to 1 g of the weight of the test fish. Determination of lethal time was defined as the time when more than half of the officials stopped gill breathing and showed no response to stimulation.

Experimental results showed that the lethal time of N-acyl glutamate was about 16 times longer than sulfates. The results for this are shown in Table 1 below.

Table 1. Test results for mild surfactant selection

2. Evaluation of Physical Properties by Surfactant

(c) Bubble force test

The foaming force was evaluated using the Rose-Miles foaming force measurement method. 1,000 grams of sample (999 grams of purified water and 1 gram of 100% raw material) were warmed to 40 ° C. After washing the cylinder with purified water once with a sample, 50 ml of the sample was filled in the lower part of the cylinder. The 200 mL sample was dropped (30 second dropping time), and the height of the bubble was measured after the end of the drop. The above operation was repeated three times to confirm that reproducibility existed and the average value was obtained. As a result, it was found that the foaming power of N-acyl glutamate was equal to or superior to that of sulfates. The results are shown in Table 2 below.

(d) cleaning power test

Detergency tests of surfactants were conducted according to ASTM D 4010. As standard contaminants, asphalt solutions having a softening point of 75 ° C. to 90 ° C., a penetration of 25 mm to 85 mm and a solubility of 90% or more to carbon tetrachloride were prepared. A standard contaminant having a diameter of 30 mm was evenly applied to five clean hands. After 5 minutes of drying, 2.5 g of each sample of 5% of each surfactant was placed in both hands and rubbed to determine the time for complete removal of the standard contaminants (each contaminant should be indistinguishable). Remove the highs and lows and average the remaining three. As a result, N-acyl glutamate was found to be comparable to that of sulfates. The results are as shown in Table 2 below.

Table 2. Foaming and cleaning power for each surfactant

According to the experimental results as described above, in the present invention, N-acyl glutamate as a main component, and selected the alkali salt of cocamidopropyl betaine, higher fatty acids, to complete a mild liquid cleanser.

Examples and Comparative Examples

Examples 1 to 5 and Comparative Examples 1 to 3: Formulation characteristics according to the amount of N-acyl glutamate

Next, the ingredients 1 to 8 were dissolved and mixed at 80 ° C. according to the composition of Table 1, and then neutralized, and then the ingredients were mixed and dissolved by adding the ingredients 9 to 10, cooled, and then mixed with ingredients 11 to 13 used in the present invention. Liquid face wash was prepared.

Table 1,

The facial cleansing composition of Example 1-5 and Comparative Example l-3 was subjected to the foaming power, cleaning power, cytotoxicity and fish toxicity experiment. Detergency, cytotoxicity, and fish toxicity test methods are the same as those described in the above mild surfactant selection experiment, and the foaming power test is the same, but the experiment concentration is 0.25% (purified water 997.5g, 2.5g sample). The difference was made between the examples and the comparative examples. The experimental results are shown in Table 2 below.

Table 2.

From the results of Table 2, when the amount of N-acyl glutamate is less than 5% by weight, the foaming power and detergency are not preferable, and when the amount is more than 40% by weight, the cytotoxicity and fish toxicity are not significantly decreased. Showing unsuccessful results. In addition, the amount of N-acyl glutamate is used within 5 to 40% by weight, showing that the foaming power, detergency, cytotoxicity, fish toxicity, etc. are preferred.

Examples 6 to 10 and Comparative Examples 4 to 6: Formulation characteristics according to the amount of cocamidopropyl betaine

Next, the ingredients 1 to 8 were mixed and neutralized at 80 ° C. according to the composition of Table 3, the ingredients 9 to 10 were added thereto, mixed and melted and cooled, and the ingredients 11 to 13 were mixed and added to the present invention. Liquid face wash was prepared.

Table 3.

The facial cleansing composition of Example 6-10 and Comparative Example 4-6 was subjected to a bubble, cleaning power, cytotoxicity and fish toxicity experiment. Detergency, cytotoxicity, and fish toxicity test methods are the same as those described in the above mild surfactant selection experiment, and the foaming power test is the same, but the experiment concentration is 0.25% (purified water 997.5g, 2.5g sample). The difference was made between the examples and the comparative examples. The experimental results are shown in Table 4 below.

Table 4.

From the results of Table 4, when the amount of cocamidopropyl betaine is less than 1% by weight, the bubble and detergency is not preferable, and when the amount is more than 30% by weight, the cytotoxicity and fish toxicity are not significantly decreased. The result is not good. In addition, it is shown that the amount of cocamidopropyl betaine is less than 1 to 30% by weight, such as foaming power, detergency, cytotoxicity, fish toxicity and the like.

Examples 11 to 14 and Comparative Examples 7 to 9 according to the dosage characteristics of lauryl acid

Next, the ingredients 1 to 8 were mixed and neutralized at 80 ° C. according to the composition of Table 5, and then the ingredients 9 to 10 were added to the mixture to dissolve and cooled, and the ingredients 11 to 13 were mixed and added to the present invention. Liquid face wash was prepared.

Table 5.

The facial cleanser composition of Examples 11-14 and Comparative Examples 7-9 was subjected to a foaming, cleaning, cytotoxicity and fish toxicity experiment. Detergency, cytotoxicity, and fish toxicity test methods are the same as those described in the above mild surfactant selection experiment, and the foaming power test is the same, but the experiment concentration is 0.25% (purified water 997.5g, 2.5g sample). There is a difference between the examples and the comparative examples. The experimental results are shown in Table 6 below.

Table 6.

From the results of Table 6, when the amount of lauryl acid is less than 1% by weight it shows that the foaming power and detergency is not preferable, when the amount of use is more than 15% by weight, the cytotoxicity and fish toxicity is not significantly decreased The results are shown. In addition, it is shown that the amount of lauric acid used is within 1 to 15% by weight, such as foaming power, detergency, cytotoxicity, fish toxicity.

Examples 15 to 18 and Comparative Examples 10 to 12: prescription characteristics according to the amount of myristylic acid used

Next, according to the composition of Table 7, dissolve and mix the raw material components 1 to 8 at 80 ° C., neutralize the raw materials, and then mix and dissolve the raw materials 9 to 10, and then cool and input and mix the raw materials to the raw materials 11 to 13 to the present invention. The liquid face wash used was prepared.

Table 7.

The facial cleansing composition of Examples 15-18 and Comparative Examples 10-12 was subjected to the foaming, cleaning, cytotoxicity and fish toxicity experiments. Detergency, cytotoxicity and fish toxicity test methods are the same as those described in the mild surfactant selection experiments, and the foaming power test is the same, but the experiment concentration is 0.25% (997.5 g of purified water 2.5g sample) The difference was made between the examples and the comparative examples. The experimental results are shown in Table 8 below.

Table 8.

From the results of Table 8, when the amount of myristylic acid is less than 1% by weight, the foaming power and detergency is not preferable, and when the amount is more than 15% by weight, the cytotoxicity and fish toxicity are significantly lowered. The results are shown. In addition, it is shown that the amount of myristylic acid is used within 1 to l5% by weight, preferably foaming power, detergency, cytotoxicity, fish toxicity.

Examples 19 to 22 and Comparative Examples 13 to 15: prescription characteristics according to the amount of stearyl acid used

Next, according to the composition of Table 9, the raw material ingredients 1 to 8 at 80 ℃ dissolved and mixed and neutralized, and then the raw material ingredients 9 to 10 was added and dissolved by mixing and cooling and the raw material ingredients 11 to 13 used in the present invention by mixing Liquid face wash was prepared.

Table 9.

The foaming, detergency, cytotoxicity and fish toxicity experiments were carried out on the face wash compositions of Examples 19-22 and Comparative Examples 13-15. The detergency, cytotoxicity and fish toxicity test methods were described in the mild surfactant selection experiment. Same as one test method, the bubble test was the same method, but the difference between the Example and Comparative Example with the experimental concentration of 0.25% (purified water 997.5g to 2.5g sample). The experimental results are shown in Table 10 below.

Table 10.

From the results of Table 10, when the amount of stearyl acid is less than 1% by weight, the foaming power and detergency is not preferable, and when the amount of use is more than 15% by weight, the cytotoxicity and fish toxicity are significantly lowered. The results are shown. In addition, it is shown that the amount of stearyl acid used within 1 to l5% by weight is preferably foaming power, detergency, cytotoxicity, fish toxicity.

3. Feeling experiment

In Example 1-22, 10 women (220 persons in total) who used makeup in their 20s were subjected to a feeling test to obtain the results as shown in Table 11. Overall, satisfaction with the feeling was significantly high, and skin irritation was obtained. Also surprisingly reduced results were obtained.

Table 11.

+++ very satisfied ++ satisfied

+ Good

Complaints

-Very dissatisfied

From the results in Table 11, it can be seen that the liquid cleansing composition of the present invention is safe for the human body, safe for the environment, and also has a very good feeling. Further, in the composition of the present invention, 5 to 40% by weight of N-acyl glutamate of formula (I), 1 to 30% by weight of cocamidopropylbetaine of formula (II) and fatty acid soap 1 of formula (III) It can be seen that it contains preferably from 15% by weight.

Claims (2)

5 to 40% by weight of N-acyl glutamate of formula (I), 1 to 30% by weight of cocamidopropyl betaine of formula (II), and 1 to 15% by weight of fatty acid soap of formula (III) Liquid face wash composition characterized in that it contains Where M ₁ represents an alkali metal cation, alkaline earth metal cation, ammonium, or the like which is a cosmetically acceptable counter ion, COR ₁ represents C ₆ -C ₃₄ acyl, R ₂ is an alkyl having 8 to 20 carbon atoms and is a fatty acid derived from animal oils such as tallow and lard, and vegetable oils such as palm oil and palm oil, M ₂ represents sodium or potassium. The face wash composition according to claim 1, wherein M ₁ is triethane.