KR0149475B1 - Mild shampoo compositions - Google Patents

Abstract

The present invention relates to N-acyl glutamate of general formula (I), cocamidopropylbetaine of general formula (II), polyoxyethylene sorbitan fatty acid ester of general formula (III) and general formula (IV) of A liquid aqueous hair shampoo composition comprising polyoxyethylene methylglucoglucose dioleate.

Wherein M +, COR, a = b + c + d, and x + y are as defined in the specification.

Description

[Name of invention]

Mild shampoo composition

Detailed description of the invention

The present invention relates to a liquid aqueous hair shampoo composition containing N-acyl glutamate as a main component and containing cocamidopropyl betaine, polyoxyethylene sorbitan fatty acid ester and polyoxyethylene methylene glucose dioleate. The shampoo composition of the present invention is safe for human body and environment.

In general, the main function of the hair shampoo is the cleaning function. Although a surfactant is mainly used as a washing | cleaning agent, various preferable and beneficial effects can be anticipated according to the kind and quantity. In addition to the cleaning function, the hair shampoo needs various functions such as sufficient foaming power, excellent feeling of use, and nourishing hair.

However, as the use of shampoo today becomes more and more common, problems about human safety and environmental safety have begun to arise. Sulfates are the most widely used surfactant in hair shampoos. These compounds have been used as main surfactants in almost all hair shampoos for reasons of good detergency, abundant foaming, and low price.

However, in recent years, there is a tendency to be a problem such as human toxicity, environmental safety. Other widely used surfactants include phosphates. Despite excellent cleaning power and low human toxicity, it has environmental safety problems such as side effects. Efforts to overcome the toxic problems of the conventional surfactants have been actively developed recently, a lot of surfactants appear to be safe for the human body and the environment, the use is increasing rapidly. Among them, a large amount of the hydrolyzed protein species as polypeptide surfactants are used as circulating surfactants, and many of them have a unique odor that is not fragrant, which causes problems in use. In addition, there have been no reported relative comparisons by objective experimental results among many surfactants which are introduced as mild.

Surfactants widely known to be mild today include:

Amino acid-based surfactants.

Polypeptide Surfactants.

Salcosinate-based surfactants.

Amine oxide surfactants.

Betaine-based surfactants.

Sulfosuccinate surfactants.

Imidazoline-based surfactants.

Phosphate-based surfactants.

Alkyl saccharide based surfactants.

Alkyl taurate surfactants.

Alkyl polyglycoside surfactants.

Polyoxyethylene sorbitan fatty acid ester surfactant.

The present inventors used a cytotoxic test method for evaluating the human safety of these surfactants, and carried out acute fish toxicity test as a means for evaluating environmental safety, and measured the foaming force as part of the evaluation of the feeling. From these results, it was found that it is desirable to use N-acyl glutamate as the main ingredient of the mild hair shampoo.

Attempts have been made to combine N-acyl glutamate with various surfactants to expect beneficial properties. European Patent Application No. 324575 (KAO) describes a cleaning composition composed mainly of nonionic surfactants, phosphate-based surfactants, N-acyl glutamate, isethionate and sulfosuccinate, and has excellent cleaning and hypoallergenic properties. It features.

Japanese Patent Application No. 77117670 (KAMEB0) describes a shampoo composition comprising N-acyl glutamate, organic carboxylic acid and phosphoric acid as its main components, and has excellent foaming power, detergency, hypoallergenicity to hair and skin. Doing.

Japanese Patent Application No. 73119550 (AJINOMOTO) discloses that a detergent mainly composed of monosodium N-oleyl-L-glutamate and lecithin is superior in cleaning power to that containing no lecithin.

Japanese Patent Application No. 7191608 (KAO SOAP) describes a cleaning composition composed mainly of N-lauryl-L-glutamic acid monosodium salt and dimethyldodecylamine oxide. As described above, many attempts have been made to produce mild hair shampoos that are hypoallergenic in the eye using N-acyl glutamate.

However, there has been no prior art for a mild shampoo composition which is excellent in various properties such as cleaning power and is safe for human body and environment with a suitable combination of mild surfactants.

The present inventors conducted comparative comparison experiments on many surfactants known to be mild, and extracted and compared the mildest surfactants. , Shampoo compositions prepared using polyoxyethylene sorbic acid fatty acid esters as nonionic surfactants and polyoxyethylene methylglucose dioleate as thickeners are substantially safe for humans, environmentally safe and have sensitive skin. It has been found that the present invention can be safely applied to human beings, and thus the present invention has been completed.

Accordingly, the present invention provides at least one N-acyl glutamate of formula (I), at least one cocamidopropyl betaine of formula (II), at least one polyoxyethylene sorbent of formula (III) A liquid aqueous hair shampoo composition characterized by containing a non-fatty acid ester and at least one polyoxyethylene methylene glucose dioleate of the following general formula (IV).

In the above formula,

M ⁺ represents a cosmetically acceptable counter ion, preferably hydrogen, an alkali metal cation, an alkali earth metal cation or ammonium, most preferably triethanolamine, COR is acyl, preferably C _6-34 -acyl, more Preferably C _8-18 -acyl, most preferably C _10-14 -acyl, a + b + c + d is a number from 3 to 80, preferably from 4 to 20, and x + y Is a number from 100 to 150, preferably 120.

In the shampoo composition according to the invention, the N-acyl glutamate of formula (I) is an amino acid based anionic surfactant. N-acyl glutamate includes, for example, monotriethanolamine N-cocoyl-L-glumethite, monotriethanolamine N-lauryl-L-glumethite, monosodium N-cocoyl-L-glutamate, and the like. .

N-acyl glutamate suitable for use in the composition according to the invention is a commercially available material and includes the following materials:

(a) Acyl glutamate CT-12: Monotriethanolamine N-cocoyl-L-glutamate, present in 30% aqueous solution.

(b) CMT-L: Monotriethanolamine N-palm oil fatty acid-L-glutamate, present in 30% aqueous solution.

In the shampoo composition according to the present invention, the amount of N-acyl glutamate of formula (I) is preferably 1 to 40% by weight, more preferably 5 to 30% by weight, most preferably 10 to 20% by weight. Suitable. If N-acyl glutamate is less than 1% by weight, the cleaning effect is weak, and more than 40% by weight of human toxicity may increase.

When N-acyl glutamate is used as the main ingredient of the shampoo, it shows better human safety and environmental safety than many other types of mild surfactants.

In the shampoo composition according to the invention, the cocamidopropylbetaine of formula (II) is an amphoteric surfactant derived from trimethylglycine. Cocamidopropylbetaine suitable for use in the present invention is a commercially available material, for example Sunbet-C present in a 30% aqueous solution. The usability of cocamidopropylbetaine as a surfactant component present in the shampoo composition according to the invention is preferably 1 to 30% by weight, more preferably 3 to 20% by weight, most preferably 5 to 15% by weight, Most suitable. If the cocamidopropyl betaine is less than 1% by weight, the cleaning effect is weak, and if it is more than 30% by weight, human toxicity may increase.

In the shampoo composition according to the present invention, the polyoxyethylene sorbitan fatty acid ester of the general formula (III) is a nonionic surfactant derived from ethylene oxide. Examples of polyoxyethylene sorbitan fatty acid esters of general formula (III) include polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monool Rate and the like.

Polyoxyethylene sorbitan fatty acid esters suitable for use in the present invention are commercially available materials and include the following materials:

(a) Tween 80: Polyoxyethylene sorbitan monooleate.

(b) Tween 20 refers to polyoxyethylene sorbitan monolaurate.

In the shampoo composition according to the invention, the amount of polyoxyethylene fatty acid ester of the general formula (III) is preferably 1 to 30% by weight, more preferably 3 to 20% by weight, most preferably 5 to 15% by weight. Suitable. If the polyoxyethylene sorbitan fatty acid ester is less than 1% by weight, the cleaning effect is weak, and more than 30% by weight of human toxicity may increase.

In the shampoo composition according to the invention, the polyoxyethylene sorbitan methylglucose dioleate of general formula (IV) is a nonionic surfactant derived from methylglucose.

Polyoxyethylene methyleneglucose dioleate suitable for use in the present invention is a commercially available material, for example glutamate DOE 120. The amount of polyoxyethylene methylglucose dioleate as a thickener present in the shampoo composition according to the present invention is preferably 1 to 15% by weight, more preferably 2 to 10% by weight, most preferably 3 to 7% by weight. Suitable. If the polyoxyethylene methyl glucose dioleate is less than 1% by weight, the thickening effect is weak, and if it is more than 15% by weight, the thickening effect may be too high or the human toxicity may increase.

The shampoo composition according to the present invention may optionally include other components within the range that does not impair its mild properties in order to improve physicochemical properties, properties, safety and the like. Examples of such other components include the following.

(a) Auxiliary surfactants: Anionic surfactants, nonionic surfactants, amphoteric surfactants and zwitterionic surfactants. 1. One or more additional surfactants selected from natural ingredients without compromising the beneficial properties of the present invention. It is preferable to have a characteristic derived from.

(b) Conditioning agents, for example, polyquaternium, isostearamidopropylolporin lactate, silicone oil, and derivatives of hydroxypropylguar gum.

(c) Moisturizers, such as glycerin and propylene glycol.

(d) Anti-dandruff agents, such as octopyrox, zinc pyridine-ethion, and the like.

(e) Preservatives, for example ethanol, benzoic acid, ketone CG and the like.

The shampoo composition of the present invention may be present in liquid or gel form in a lid container or tube container such as a bottle.

Although an Example is given to the following and this invention is demonstrated to these, these Examples do not limit the technical scope of this invention.

Experimental Example

[Moderate raw material selection experiment]

The components of the shampoo composition according to the present invention are circulating components that have been tested as follows.

(a) Cytotoxicity test

A type of in vivo test for predicting human safety. It is a method for evaluating safety at the cellular level. After culturing 3T3 fibroblasts on the plate, the samples to be tested were inoculated by concentration (1,000, 800, 600, 400, 200, 100, 80, 60, 40, 20 (μg / ml)) and then incubated daily Check the concentration. The higher the half-dimension concentration, the lower the irritation. The experimental results showed that the half-density concentration of N-acyl glutamate was about 10 times higher than that of sulfates. The results are shown in Table 1.

(b) Acute fish toxicity test

One group of ten healthy fish fish fasted for one day was placed in a group and placed in a water bath containing a constant concentration (300 ppm) of surfactant to observe the lethal time.

The tank was equipped with an air injection device and a circulation filtration device, and no feed was added during the experiment. The amount of experimental water was 1 L or more with respect to 1 g of the weight of the test fish. Determination of lethal time was defined as the time when more than half of the gills of the official fish stopped breathing and showed no response to the stimulus. Experimental results showed that the lethal time of N-acyl glutamate was about 16 times longer than sulfate.

(c) Bubble force test

The foaming force was evaluated using the Rose-Miles foaming force measurement method. 1,000 grams of sample (999 grams of purified water and 1 gram of 100% raw material) are warmed to 40 ° C. After washing the cylinder washed with purified water once with a sample, 50 ml of the sample is filled in the lower part of the cylinder. A 200 ml sample is dropped (30 seconds from the parachute) and the height of the mark is measured after the drop is completed. The above operation is repeated three times to confirm that the anti-static property is obtained and to obtain an average value. Experimental results showed that the foaming power of N-acyl glutamate is comparable to or superior to that of sulfates. The results are shown in Table 1.

According to the above experimental results, in the present invention, N-acyl glutamate as an anionic surfactant, cocamidopropylbetaine as an amphoteric surfactant, polyoxyethylene sorbitan monooleate as a nonionic surfactant, and polyoxy as a thickener Ethyl methylglucose dioleate was selected.

[Examples and Comparative Examples]

To prepare a shampoo composition according to the conventional shampoo manufacturing method with a composition as shown in Table 2.

(Note 1) Ⅰ: N-acyl glutamate

Ⅱ: Cocamidopropyl Betaine

III: Polyoxyethylene Sorbitan Monooleate

IV: Polyoxyethylene Methylglucose Dioleate

(Note 2) The above figures are all weight percent.

[Evaluation of Examples and Comparative Examples]

The shampoo composition prepared above was subjected to cytotoxicity evaluation (anti-lethal concentration), acute fish toxicity evaluation and foaming capacity evaluation in Table 3 below.

As can be seen from the results, it can be seen that the shampoo composition of the present invention is safe for the human body and safe for the environment. Further, in the composition of the present invention, 1 to 40% by weight of N-acyl glutamate of general formula (I), 1 to 30% by weight of cocamidopropylbetaine of general formula (II), polyoxyethylene sorbitan of general formula (III) It can be seen that it is preferable to contain 1 to 30% by weight of fatty acid ester and 1 to 15% by weight of polyoxyethylene methylglucoglucose dioleate of general formula (IV).

Claims (5)

1 to 40% by weight of N-acyl glutamate of the following general formula (I), 1 to 30% by weight of cocamidopropylbetaine of the following general formula (II), one or more of the following general formula (III) A liquid aqueous hair shampoo composition comprising 1 to 30% by weight of polyoxyethylene sorbitan fatty acid ester and 1 to 15% by weight of one or more polyoxyethylene methylene glucose dioleate of the following general formula (IV). Wherein M ⁺ represents a cosmetically acceptable counter ion, COR represents acyl, a + b + c + d is a number from 3 to 80, and x + y is a number from 100 to 150. The shampoo composition of claim 1 wherein M ⁺ is hydrogen, an alkali metal cation, triethanolamine, alkaline earth metal cation or ammonium salt. The shampoo composition of claim 1 wherein COR is 10 _10-14- acyl. 2. The shampoo composition of claim 1 wherein x + y is 120. The shampoo composition of claim 1 wherein a + b + c + d is 4-20.