KR100420758B1 - Photostabilized Fungicide That Contains Ethaboxam and its Photostabilizer, Method for Fungicidal Use and Method for Increasing Photostability of Ethaboxam - Google Patents

Abstract

The present invention relates to a photostabilizing bactericide composition containing etaboksam ( N- (α-cyano-2-tenyl) -4-ethyl-2-ethylamino-5-thiazolecarboxamide) and a light stabilizer thereof, The present invention relates to a sterilization method and a method for improving the light stability of etaboksam, wherein etaboksam and its photostabilizer are 3,5-di-tert-butyl-4-hydroxybenzyl phosphonic diethyl ester, 2,2'-chiodi Ethyl-bis [3- (3,5-di-tert-butyl-4-hydroxyphenyl) -propionate, 2,6-di-tert-butyl-4-methylphenol, 2-hydroxy- 4-methoxybenzophenone, octyl methoxy cinnamate, 2,4,6-trianilino-para- (carbo-2'-ethylhexyl-1'-oxy) -1,3,5-triazine Provided is a light stabilized fungicide composition containing enhanced photo stability and duration of adverse effects, a method for sterilizing plant pathogens using the same, and a method for improving light stability of etaboksam by the light stabilizer.

Description

Photo-stabilized Fungicide That Contains Ethaboxam and its Photostabilizer, Method for Fungicidal Use and Method for Increasing Photostability of Ethaboxam}

The present invention relates to N- (α-cyano-2-tenyl) -4-ethyl-2-ethylamino-5-thiazolecarboxamide (ISO proposal name: ethaboxam, etaboksam, hereinafter referred to as "etaboksam") And a light stabilizing fungicide composition containing the light stabilizer, a sterilization method using the same, and a method of improving the light stability of etaboksam, and more particularly, 3,5-di-tertries-butyl-4, which is a light stabilizer of etaboksam. -Hydroxybenzyl phosphonic diethyl ester, 2,2'-thiodiethyl-bis [3- (3, 5-di-tert-butyl-4-hydroxyphenyl) -propionate, 2,6- Di-tert-butyl-4-methylphenol, 2-hydroxy-4-methoxybenzophenone, octyl methoxy cinnamate, 2,4,6-trianilino-para- (carbo-2'-ethyl Of N- (α-cyano-2-tenyl) -4-ethyl-2-ethylamino-5-thiazolecarboxamide using hexyl-1′-oxy) -1,3,5-triazine Photo-stabilizing disinfectant composition with enhanced photo-stability and drug duration, It relates to a sterilization method using the same and a method for improving the light stability of etaboksam by the light stabilizer.

In recent years, as the environmental pollution problem caused by pesticides has emerged significantly, the development and use of pesticides should be premised on securing safety for humans and the environment. Therefore, recently developed pesticide raw materials are generally excellent in drug efficacy even when used in low doses, and is characterized by high environmental and human safety compared to conventional pesticide raw materials.

Therefore, many of the recently developed pesticide raw materials have a special or complex chemical structure, and there are factors that are unstable to light due to the introduction of special substituents in the molecule, the introduction of double bonds and triple bonds, and the presence of ultraviolet absorbers. do. In addition, optimization of biological activity of pesticide raw materials may involve chemical destabilization such as photodegradability. Despite the advantages of low toxicity and high activity, these compounds are decomposed by photochemical reactions such as ultraviolet rays and lose their activity under packaging conditions. In this case, the number of times of use of pesticides to express the appropriate medicinal effect is increased, the total amount of pesticides administered in the environment is increased, and the excessively used pesticides and their degradation products remain or enter the soil and water system, causing environmental problems. Cause. Therefore, enhancement of photostability of pesticide raw materials sensitive to light conditions is an essential consideration in relation to environmental issues as well as commercialization of pesticide raw materials.

The method of imparting photostability of pesticides that are sensitive to light differs depending on the types of pesticides and the types and amounts of photostabilizers used. In general, the type of light stabilizer that can improve the light stability of the pesticide raw material is roughly divided into ultraviolet light shielding agent (Japanese Patent Laid-Open No. 11-292707) by inorganic substances such as ultraviolet absorbers (US Pat. No. 5597574), which are organic compounds, and metal salts.

In order to enhance the photodegradation effect of the pesticide raw material by the use of a light stabilizer, a method of encapsulating the formulation or forming a water-insoluble film on the surface of the crop sprayed with pesticides is used (US Patent 5597574, Japanese Patent Laid-Open). 51-133419).

The enhancement of pesticides by the use of light stabilizers is clearly observed in the case of light unstable compounds such as insect hormones and pesticide active substances derived from insects, and efforts to improve the commercialization by improving the photodegradability of these pesticide active compounds are constantly made. (US Pat. Nos. 4045555, 5994266).

Meanwhile, etaboxam of formula (1), which is a kind of 2-aminothiazolecarboxamide derivative, is a bactericidal active substance for crop protection in Korean Patent No. 124552 (Application No. 94-19960, which is specifically cited herein). Already described, preparations containing etaboxam (commercialized by Ami Co., Ltd.—trade name: Guardian (hydrate)) are also known;

The present inventors have selected a group of substances exhibiting various types of photostability enhancing effects widely used in other industries in order to enhance the duration of medicinal effects by enhancing the photostability of etaboksam based on their structural characteristics. During the photostability enhancement test, it was confirmed by instrumental analytical method that some of the substance groups had the photostability enhancement effect of etaboksam, and a single packaged bactericide containing them was prepared to conduct the duration improvement test of the drug efficacy. Was done. As a result, it was found that the duration of the medicament was markedly enhanced by the addition of some candidates for the light stabilizer for etaboksam at the same concentration of etaboksam, thereby completing the present invention.

Therefore, the present invention, by reducing the degradation rate of the etaboksam by light in the environment, the duration of the medicinal effect against the plant disease compared to the existing etaboksam containing formulations and environmentally beneficial fungicide composition, sterilization method using the same and The purpose of the present invention is to provide a method for improving the light stability of etaboksam.

In order to achieve the above object, the present invention, etaboksam and 3,5-di-tert-butyl-4-hydroxybenzyl phosphonic diethyl ester as a light stabilizer of etaboksam (Formula 2), 2, 2 ′ -Thiodiethyl-bis [3- (3, 5-di-tersus-butyl-4-hydroxyphenyl) -propionate (Formula 3), 2, 6-di-tersus-butyl-4- Methylphenol (Formula 4), 2-hydroxy-4-methoxybenzophenone (Formula 5), octyl methoxy cinnamate (Formula 6), 2, 4, 6-trianilino-para- (carbo-2 Fungicide composition containing one or more '-ethylhexyl-1'-oxy) -1, 3, 5-triazine (Formula 7), sterilization method of phytopathogens using the same and improving the light stability of etaboksam by the light stabilizer Provide a method.

Hereinafter, the present invention will be described in detail.

In the present invention, the material showing photodegradation inhibitory effect on etaboksam is a non-pesticide component, 3,5-di-tert-butyl-4-hydroxybenzyl phosphonic diethyl ester (Formula 2), 2, 2'-value Odiethyl-bis [3- (3, 5-di-tert-butyl-4-hydroxyphenyl) -propionate (Formula 3), 2, 6-di-tert-butyl-4-methylphenol ( 2-hydroxy-4-methoxybenzophenone (Formula 5), octyl methoxy cinnamate (Formula 6), 2, 4, 6-trianilino-para- (carbo-2'-ethyl Hexyl-1'-oxy) -1, 3, 5-triazine (Formula 7) and the like.

In particular, 2-hydroxy-4-methoxy benzophenone showed the best effect on the inhibition of photolysis of etaboksam.

Etaboxam fungicide composition of the present invention with enhanced stability is 1 to 70% by weight, preferably 5 to 50% by weight, 1 to 70% by weight, preferably 2.5 to 20% by weight, photolysis inhibitor, solid or liquid 29 to 98% by weight of carrier or additive and 0 to 69% by weight of surfactant, preferably 0.1 to 10% by weight. When the amount of etaboksam is less than 1% by weight, it is difficult to match the dilution factor, and when it exceeds 70% by weight, it is difficult to maintain the physical properties of the formulation by adding a photolysis inhibitor.

3, 5-di-tersus-butyl-4-hydroxybenzyl phosphonic diethyl ester, 2, 2′-thiodiethyl-bis [3- (3, 5-di-tersery in the composition according to the invention -Butyl-4-hydroxyphenyl) -propionate, 2, 6-di-terresy-butyl-4-methylphenol, 2-hydroxy-4-methoxybenzophenone, octyl methoxy cinnamate, 2, 4, 6-trianilino-para- (carbo-2'-ethylhexyl-1'-oxy) -1, 3, 5-triazine enhanced the photostability of etaboxam under artificial and natural light conditions. Therefore, the photolysis rate of etaboksam is reduced by the use of the light stabilizer, so that the efficacy of the fungicide composition may be stably expressed.

The reason why the photodegradation substance enhances the efficacy of etaboksam against plant diseases is believed to be due to improving the photostability of the sprayed etaboksam to enhance the duration of the medicinal effect. Can be deduced from the difference.

In the present invention, etaboxam to photolysis inhibitor is used in a weight ratio of about 1: 0.1 to 1: 1, preferably about 1: 0.2 to 1: 0.5.

The fungicide composition according to the present invention is effective for the prevention and treatment of diseases caused by pathogens of the following crops: gerbera late blight [pathogen: Phytophthora cryptogea ], potato late blight [pathogen: phytophthora infestans ( Phytophthora infestans)], pepper blight [pathogens: Pastry Saratov Torah kaepsi City (Phytophthora capsici), tomato late blight [pathogens: Pastry Saratov Torah inpe Afghanistan's (Phytophthora infestans)], tobacco epidemic [pathogens: Pastry Saratov Torah Nico Tia four (Phytophthora nicotianae var.nicotianae )], sesame late blight [pathogen: Phytophthora nicotianae var. parasitica ], apple late blight [pathogen: Phytophthora cactorum ], melon mycobacterium [pathogen: Pseudofero Pseudoperonospora cubensis ], melon mycobacterium [pathogen: Pseudoperonospora cubensis ], cucumber mycobacteria [pathogen: Pseudoperonospora cubensis ], Chinese cabbage fungus [pathogen: Peronospora parasitica ], lettuce fungi [pathogen: Bremia lactucae ], rose fungus [pathogen: Ferro Peronospora sparsa ], Staphylococcus aureus [pathogen: Plasmopara viticola ], Hoff aureus [pathogen: Pseudoperonospora humuli ], grass pisium blight disease [pathogen] : Phythium spp.]

Fungicide compositions containing photodegradation inhibitors according to the present invention, where necessary, are used in combination with carriers, surfactants or auxiliaries commonly used in the formulation art. For example, they are processed in unmodified form according to known methods, for example, wetting agents, dispersible liquids, in which the active ingredient is uniformly mixed and / or ground with an extender [e.g., a solvent, a solid carrier and, if appropriate, a surfactant]. It is processed into formulations such as emulsions, granulating water hydrants, liquid hydrating agents and oily suspensions, and used by spraying on foliar and stem of plants. Dosage frequency and dosing rate depend on the biological characteristics of the pathogen and the climatic environment.

Suitable carriers and additives may be solid or liquid and ingredients useful in the formulation art are used, for example natural or synthetic inorganics, solvents, dispersants, wetting agents, diluents and the like.

Possible solvents are polar solvents such as N -methyl-2-pyrrolidone, dimethyl sulfoxide or dimethyl formamide. Cosolvents also include long chain alcohols such as N -octyl-2-pyrrolidone, substituted naphthalenes, xylene mixtures, substituted benzenes, decyl alcohols, dodecyl alcohols and long chain ester compounds.

Possible as solid carriers are finely ground natural minerals such as talc, kaolin, calcium carbonate, diatomaceous earth, leadstone. In addition, water-soluble ionic compounds such as anhydrous sodium sulfate or hydrophilic porous synthetic compounds can be used to improve the physical properties of the formulation, in particular the hydration properties.

Suitable surfactants are used having a variety of properties depending on the nature and formulation of etaboxam, but mainly nonionic and / or anionic surfactants having good wetting and dispersing power. Surfactant herein also means a surfactant mixture.

As the wetting agent, anionic wetting agents such as sodium lauryl sulfate, salts of polyoxyalkylene alkyl phenyl ether sulfonic acid, salts of dialkyl sulfosuccinate, salts of dialkyl naphthalene sulfonic acid, salts of polyoxyalkylene alkyl ether sulfate and acetylene series Nonionic surfactants, urea complexes of nonionic surfactants, etc. may be used, but more suitable are sodium lauryl sulfate, salts of polyoxyalkylene alkyl aryl ether sulfonic acid, salts of polyoxyalkylene alkyl ether sulfate, nonionic interface Urea complexes of the active agent.

As a dispersant, in the case of powder formulations, such as salts of lignin sulfonic acid, salts of naphthalene sulfonic acid, salts of lauryl sulfate, salts of lauryl sulfonic acid, salts of polyoxyalkylene alkyl aryl ether sulfate, salts of polyoxyalkylene alkyl ether sulfate And anionic dispersants and nonionic dispersants such as polyoxyalkylene alkyl aryl ethers, polyoxyalkylene alkyl ethers, acrylic graft copolymers, and the like.

In the case of liquid formulations, dispersants may use nonionic surfactants having good dispersibility, such as polyoxyalkylene alkyl aryl ethers, preferably polyoxyalkylene tristyryl phenol ethers and polyoxyalkylene alkyl ethers. These dispersants are often useful as wetting agents.

Wetting agents and dispersants are not limited to those described above, and any suitable nonionic, anionic surfactant may be used.

Hereinafter, although an Example, a comparative example, and a test example are given and this invention is demonstrated concretely, these are only a part of this invention and do not limit this invention.

Example 1 Preparation of Fungicide Compositions of the Present Invention and Fungicide Compositions of Comparative Examples

A fungicide composition containing the component of the following formulation example was prepared.

In the Examples, unless otherwise stated,% means% by weight. In the table, Escalol represents International Specialty Products (US), Irganox represents Ciba Specialty Products (Switzerland), and Uvinol represents BASF (Germany).

Formulation Examples 1-6 (Hydrating Agent)

The active ingredient etaboksam and each of the etaboksam photolysis inhibitors, surfactants, and extenders were uniformly mixed using a plastic bag and then pulverized in a suitable mill to prepare a desired hydrating agent (Table 1).

Formulation example One 2 3 4 5 6 Etaboksam 25% 25% 25% 25% 25% 25% CLS ^{Note 1)} 5% 5% 5% 5% 5% 5% SDS ^{Note 2)} 2% 2% 2% 2% 2% 2% Irganox 1222 ^{Note 3)} 10% - - - - - Irganox 1035 ^{Note 4)} - 10% - - - - BHT ^{Note 5)} - - 10% - - - Ascalol 567 ^{Note 6)} - - - 10% - - Ascalol 557 ^{Note 7)} - - - - 10% - Uvinol T150 ^{Note 8)} - - - - - 10% kaoline 58% 58% 58% 58% 58% 58%

Note 1): Lignin sulfonic acid calcium salt

Note 2): Sodium Lauryl Sulfate

Note 3: 3, 5-di-terther-butyl-4-hydroxybenzyl phosphonic diethyl ester

Note 4): 2, 2'-thiodiethyl-bis [3- (3, 5-di-tert-butyl-4-hydroxyphenyl) -propionate

Note 5): 2, 6-di-tert-butyl-4-methylphenol

Note 6) 2-hydroxy-4-methoxy benzophenone

Note 7: Octyl methoxy cinnamate

Note 8): 2, 4, 6-trianilino-para- (carbo-2'-ethylhexyl-1'-oxy) -1, 3, 5-triazine

Formulation Examples 7-12 (Dispersable Liquid)

Dissolved Etaboxam was dissolved in N -methyl-2-pyrrolidone as a solvent, and then dissolved by adding a photolysis inhibitor and other auxiliary agent for Etaboxam (Table 2).

Formulation example 7 8 9 10 11 12 Etaboksam 12.5% 12.5% 12.5% 12.5% 12.5% 12.5% NK-TP120 ^{Note 1)} 15% 15% 15% 15% 15% 15% Irganox 1222 10% - - - - - Irganox 1035 - 10% - - - - BHT - - 10% - - - Ascalol 567 - - - 10% - - Ascalol 557 - - - - 10% - Uvinol T150 - - - - - 10% NMP ^{Note 2)} 62.5% 62.5% 62.5% 62.5% 62.5% 62.5%

Note 1): Polyoxyethylene Tristyryl Phenyl Ether (Coseal Products)

Note 2) N -methyl-2-pyrrolidone

Formulation Examples 13-15 (Hydrating Agent)

Wetting agents were prepared by the same method as in Preparation Examples 1 to 6 (Table 3).

Formulation example 13 14 15 Etaboksam 25% 25% 25% CLS 5% 5% 5% SDS 2% 2% 2% Ascalol 567 5% 15% 20% kaoline 63% 53% 48%

Comparative Example

Comparative Example 1 (Hydrating)

Ethaboxam, auxiliaries and extenders were all put in a plastic bag, mixed uniformly and ground in a suitable mill to prepare a hydrating agent (Table 4).

Comparative Example 1 Etaboksam 25% CLS 5% SDS 2% kaoline 68%

Comparative Preparation Example 2 (Dispersable Liquid)

Etaboxam was dissolved in N -methyl-2-pyrrolidone as a solvent and then dissolved by adding the remaining auxiliary agent to prepare a dispersible liquid (Table 5).

Comparative Example 2 Etaboksam 12.5% NK-TP120 15% NMP 72.5%

Example 2 Light Stability Evaluation

If the photostability of etaboxam in the etaboxam fungicide composition to which the photolysis inhibitor is added is higher than that in the composition to which the photolysis inhibitor is not added, it means that there is a photolysis inhibitory effect of etaboksam by the addition of the photolysis inhibitor.

Test Example 1: Evaluation of light stability in artificial light

The test preparation was prepared by diluting the test preparation with water to 160 mg / L based on the raw material, and dispensing 1 ml of the petri dishes with a diameter of 87 mm to put 160 µg into the petri dishes. 4 ml of water was added and shaken to allow the preparation to spread evenly in Petri dishes, and then allowed to evaporate in an oven controlled at 50 ° C. Petri dishes containing drugs were irradiated with light for 1 to 4 hours under artificial light (ultravitalux lamps, OSRAM). The treated petri dish was dissolved by adding 5 ml of acetonitrile, and quantitatively analyzed undecomposed etaboksam using HPLC.

The results are shown in Table 6 and Table 7 below. In general, the hydrated treatment was better in light stability of etaboksam than the dispersible liquid treatment, and the photodegradation of etaboksam was suppressed in the treatment added with the light stabilizer candidate compared to the treatment without addition. In particular, the best results were observed in the test zone treated with the hydrating agent of Formulation Example 4 to which 2-hydroxy-4-methoxy benzophenone was added.

% Of undissolved etaboksam by formulation Formulation Example 1 Formulation Example 2 Formulation Example 3 Formulation Example 4 Formulation Example 5 Formulation Example 6 Comparative Example 1 Guardian 1 hours 85 88 87 90 88 89 86 85 2 hours 72 80 68 82 70 72 65 63 3 hours 58 69 56 71 56 60 45 47 4 hours 39 58 36 60 44 35 25 21

% Of undissolved etaboksam by formulation Formulation Example 7 Formulation Example 8 Formulation Example 9 Formulation Example 10 Formulation Example 11 Formulation Example 12 Comparative Example 2 1 hours 81 83 84 85 80 82 80 2 hours 66 67 64 66 62 65 56 3 hours 51 56 48 60 55 53 44 4 hours 40 43 37 48 36 32 18

Test Example 2 Evaluation of Light Stability in Natural Light

The test preparation was prepared by diluting the test preparation with water to 160 mg / L based on the raw material, and dispensing 1 ml of the petri dishes with a diameter of 87 mm to put 160 µg into the petri dishes. 4 ml of water was added and shaken to allow the preparation to spread evenly on the Pecrichish, and then allowed to evaporate in an oven controlled at 50 ° C. Petri dishes containing the drug were irradiated with light for 1 to 7 days under natural light. The treated petri dish was dissolved by adding 5 ml of acetonitrile, and quantitatively analyzed undecomposed etaboksam using HPLC.

The results are shown in Table 8 and Table 9 below. Overall, the light stability of etaboksam was higher in the natural light treatment than in the artificial light treatment, and the decomposition of etaboksam was suppressed in the treatment treatment to which the photodegradation inhibitor was added as in the artificial light treatment. In particular, the best results were observed in the test zone treated with the hydrating agent of Formulation Example 4 to which 2-hydroxy-4-methoxy benzophenone was added.

% Of undissolved etaboksam by formulation Formulation Example 1 Formulation Example 2 Formulation Example 3 Formulation Example 4 Formulation Example 5 Formulation Example 6 Comparative Example 1 Guardian 1 day 83 87 85 88 84 85 82 84 3 days 69 72 66 73 69 67 50 52 5 days 55 59 50 63 58 52 44 43 7 days 40 55 38 56 45 39 33 31

% Of undissolved etaboksam by formulation Formulation Example 7 Formulation Example 8 Formulation Example 9 Formulation Example 10 Formulation Example 11 Formulation Example 12 Comparative Example 2 1 day 80 82 81 84 81 79 77 3 days 65 65 60 66 60 63 50 5 days 54 53 47 55 49 51 37 7 days 41 40 29 46 33 34 22

Example 3. Biological Activity Assessment

The biological activity was evaluated using the hydration agent of etaboxam containing 2-hydroxy-4-methoxy benzophenone, which was observed to have the highest photodegradation inhibitory effect of etaboksam according to Test Examples 1 and 2, and the medicinal effect against tomato late blight. Was conducted through a duration improvement effect test of.

Tomato seeds were sown in horticultural tops of 6 cm diameter pots and grown in greenhouses for 4 weeks. Using the preparation prepared in Formulation 4, Formulations 13-15 and Comparative Example, and a guardian hydrating agent at a concentration of 1, 5, 10, 50, 100 mg / L, based on the original formulation, 5 ml of spray solution per pot was sprayed onto tomato leaves and stems, and left for 1, 5, and 10 days in the open air to receive sufficient light. Phytophthora infestans, a tomato late blight strain prepared at a concentration of 5 × 10 ⁴ strainers / ml after 1, 5 and 10 days of drug spraying, was inoculated into plants using an automator. Inoculated tomatoes were developed at 20 ° C. and 100% relative humidity conditions for 3 to 4 days, and then removed when the incidence of the untreated plots was about 80%, and the incidence was examined.

The results were shown by dividing the control value after natural day treatment (Table 10), the control value after natural day 5 treatment (Table 11), and the control value after natural day 10 treatment (Table 12). The control value of the natural light treatment group showed similar results in all treatments, but the control value of the natural light treatment group showed enhanced efficacy compared to the treatment group without the addition of 2-hydroxy-4-methoxy benzophenone. It was possible (Table 12).

Therefore, the phenomenon of enhancement of the duration of the medicinal effect by the addition of 2-hydroxy-4-methoxy benzophenone is apparent, which is considered to be due to the suppressed photolysis of etaboksam.

Concentration (mg / L) Control is (%) Comparative Example 1 Formulation Example 13 Formulation Example 4 Formulation Example 14 Formulation Example 15 Guardian One 93 92 93 93 94 92 10 97 99 98 99 99 98 50 100 100 100 100 100 100 100 100 100 100 100 100 100

Concentration (mg / L) Control is (%) Comparative Example 1 Formulation Example 13 Formulation Example 4 Formulation Example 14 Formulation Example 15 Guardian One 80 83 85 85 88 81 10 85 88 90 91 94 85 50 93 95 98 99 99 94 100 96 98 100 100 100 97

Concentration (mg / L) Control is (%) Comparative Example 1 Formulation Example 13 Formulation Example 4 Formulation Example 14 Formulation Example 15 Guardian One 31 39 49 65 69 32 10 45 55 64 78 80 48 50 72 80 83 90 90 75 100 83 88 90 92 94 82

As described above, according to the present invention, the light stabilizer of etaboksam enhances the light stability of etaboksam, thereby reducing the degradation rate of the light by etaboksam in the environment, and compared to the conventional etaboksam-containing formulation, In addition, it is possible to improve the duration of the pesticides, and from the environmental point of view, there is a desirable effect of preserving the soil and water environment by minimizing the number of spraying and spreading of pesticides.

Claims (11)

Etaboxam and its light stabilizers 3,5-di-tersus-butyl-4-hydroxybenzyl phosphonic diethyl ester, 2,2'-thiodiethyl-bis [3- (3,5- Di-tert-butyl-4-hydroxyphenyl) -propionate, 2,6-di-tert-butyl-4-methylphenol, 2-hydroxy-4-methoxybenzophenone, octyl methoxy cinna Mate and any substance selected from the group consisting of 2,4,6-trianilino-para- (carbo-2'-ethylhexyl-1'-oxy) -1, 3, 5-triazine and , The light stabilizer composition of Eta boksam and the Eta boksam contained in a weight ratio of 1: 0.1 to 1: 1. (delete) The method of claim 1, The light stabilizer disinfectant composition comprising any one selected from the group of the etaboksam and the light stabilizer material of the etaboksam in a weight ratio of 1: 0.2 to 1: 0.5. The method according to claim 1 or 3, The light stabilizer fungicide composition, characterized in that any one selected from the group of light stabilizer substances of etaboksam is 2-hydroxy-4-methoxybenzophenone. The method of claim 1, The light stabilizer disinfectant composition is 1 to 70% by weight of etaboxam, 1 to 70% by weight of any one selected from the group of light stabilizer substances of the etaboksam, 0.1 to 69% by weight of the surfactant and 29 to 97% by weight of the carrier Photo-stabilizing fungicide composition containing. A method for sterilizing plant pathogens, wherein the preparation containing the fungicide composition of claim 1 is sprayed onto the plant. The method of claim 6, The sterilant composition is a method for sterilizing plant pathogens, characterized in that any one selected from the group of etaboksam and the light stabilizer material of the etaboksam in a weight ratio of 1: 0.1 to 1: 1. The method of claim 6, The sterilant composition is a method for sterilizing phytopathogens, characterized in that any one selected from the group of etaboksam and the light stabilizer material of the etaboksam in a weight ratio of 1: 0.2 to 1: 0.5. The method according to any one of claims 6 to 8, Sterilization method of plant pathogens, characterized in that any one selected from the group of the light stabilizing substances of etaboksam is 2-hydroxy-4-methoxybenzophenone In etaboksam, 3,5-di-tersus-butyl-4-hydroxybenzyl phosphonic diethyl ester, a light stabilizer of etaboksam, 2,2′-thiodiethyl-bis [3- (3,5- Di-tert-butyl-4-hydroxyphenyl) -propionate, 2,6-di-tert-butyl-4-methylphenol, 2-hydroxy-4-methoxybenzophenone, octyl methoxy cinna Add any one material selected from the group consisting of mate, 2,4,6-trianilino-para- (carbo-2'-ethylhexyl-1'-oxy) -1, 3, 5-triazine Method for improving the light stability of etaboksam, characterized in that. The method of claim 10, The method of improving the light stability of etaboksam, characterized in that any one selected from the group of the light stabilizing substances of etaboksam is 2-hydroxy-4-methoxybenzophenone.