KR100298238B1 - Oil-in-oil emulsion composition - Google Patents

Abstract

In the slit scanning exposure apparatus, a predetermined number of pulsed lights are emitted from a pulsed light source to transfer a pattern onto a reticle of a wafer, while the reticle wafer is scanned at a constant speed with respect to an exposure area on the wafer. In this case, not only the energy variation of the pulsed light but also the light emission time of the pulsed light are taken into consideration.

Description

Oil-in-water emulsion composition

1 is a schematic diagram of an emulsification state of a general oil-in-water emulsion composition.

2 is a view for explaining the deterioration factors of the emulsion stability of a general oil-based emulsion composition.

3 is a view for explaining the emulsification state of the oil-in-water emulsion composition according to the present invention.

4 is a diagram for explaining a DSC temperature rise curve of an oil-in-water emulsion composition according to the present invention.

* Explanation of symbols for main parts of the drawings

10: award 12: paid

14 Surfactant 16: Amphiphilic Substance

The present invention relates to an oil-in-water emulsion composition, and in particular to the improvement of its physical properties.

Conventionally, various emulsion compositions have been widely used in fields such as cosmetics.

Most of these emulsion compositions are in the form of creams or turbid emulsions, but for improving the appearance, the emulsion compositions in which the emulsion particle size is reduced and the oily ingredients are stably blended are also being developed. (Japanese Patent Laid-Open No. 88-88) 126542, Japanese Patent Application Laid-Open No. 88-126543, Japanese Patent Application Laid-Open No. 89-288330, etc.) These emulsion compositions have attracted attention as a technology in which oily components are stably formulated without using a large amount of surfactants and ethanol. .

The conventional emulsified composition is very excellent in terms of its stability and transparency, but various studies have been conducted to obtain an excellent usability and the like.

That is, in a container, the physical property of the aqueous solution which is excellent in clarity, the viscosity is low, and the usability at the time of filling or taking out is preferable, and when it is applied to skin, a creamy soft touch is desired.

However, in such conventional technical knowledge, an emulsion composition having opposing physical properties has not yet been obtained.

The present invention has been made in view of the above problems of the prior art, and an object thereof is to provide an oil-in-water emulsion composition having an aqueous solution property and a creamy feel.

As a result of earnestly examining by the present inventors etc. in order to achieve the said objective, in the oil-in-water emulsion composition, the boundary part of the oil phase which is an internal phase, and the water phase which is an external phase is found. In the aqueous phase, the presence of a substantial amount of the amphoteric affinity substance and the surfactant which can form a gel, the present invention has been found to have the physical properties of the aqueous solution and to impart a creamy feel to the present invention to complete the present invention. .

That is, generally, in an oil-in-water emulsion composition, it is thought that an amphiphilic substance and surfactant form the gel in water phase and solidify the base. (Barry, BW, Journal Colloidal Interface Science 28, 82-91 (1968), etc.), and the creamy feel is derived from the flow characteristics of the gel formed by both lipophilic substances and surfactants in the water phase.

In this oil-in-water emulsion composition, the gel formation state is described as follows. (Fukushima massage, physicochemistry of cetyl alcohol, Fragrance Journal, 1992. P112-116). In FIG. 1, the oil phase 12 is dispersed in the water phase 10, and a surfactant 14 and an amphiphilic substance 16 are present at the interface between the water phase 10 and the oil phase 12, and the water phase 10 Stabilization of the dispersed state of the oil phase 12 in the inside is achieved. In addition, surfactant 14 and an amphoteric material 16 are also present in the water phase 10, and a part of the surfactant 14 and the amphoteric material 16 may form a lamellar structure 18. It is formed in the water phase, and the gel structure is established to provide the creamy feeling with the solidification of the base.

Such an oil-in-water-like composition destroys the gel structure processed in an emulsifier with strong cutting force and solidifies the base, for example, a dispersion system (vesicle) having a fine lamellar structure as shown in FIG. As a result, a low-viscosity liquid base can be obtained (Michihiro Yamaguchi, Nodasho, Nikka 26-32 (1989)). However, a finely dispersed system of lamellar structures has problems of destabilization such as generation of foot sediment due to aggregation and viscosity increase due to reconstruction of the gel structure.

Thus, the present inventors have refined the emulsion particles of the oil-in-water emulsion composition composed of the amphoteric (16) -surfactant (14) -water (10) -oil (12) to form a gel in the water phase. The amphiphilic material 16 and the surfactant 14 to the emulsion particle interface to reduce the amount of gel in the water phase and to form a stable gel to destroy the gel structure and then difficult to form a gel structure again Selecting a combination of materials and surfactants makes the cream a low viscosity liquid and ensures stability at the product level.

That is, as shown in FIG. 3, the amphiphilic material 16 and the surfactant 14 are transferred to the interface of almost all of the oil droplets 12 as the amphiphilic material 16 and the surfactant ( 14) is stable in the emulsion particle interface, and since the finely dispersed lamellar structures, etc. do not exist in the aqueous phase 10, the sediment precipitates due to the aggregation and the reconstruction of the gel structure are also present. Can't happen. Therefore, the oil-in-water emulsion composition which concerns on this invention is very low viscosity in the storage state, and has the outstanding manufacturing suitability and usability at the time of taking out from a container.

Then, when the emulsion composition as shown in FIG. 3 is applied to the skin, for example, mechanical breakdown of the emulsion particles occurs due to a painting action, and the surface area of the emulsion particle interface is significantly reduced. As a result, the amphiphilic material 16 and the surfactant 14 are released in the water phase, and the gel structure is reconstructed from the amphiphilic material (16) -surfactant (14) -water (10) to give a creamy feeling Can be given.

Thus, in actual use, the oil-in-water emulsified composition which has the very novel feel which a feeling of cream reproduces with the destruction of an emulsion in application | coating process was developed.

In other words, the oil-in-water emulsion composition according to claim 1 of the present application is (1) an amphiphilic substance selected from among those capable of forming a gel at room temperature or higher in both lipophilic-surfactant-aqueous systems and Surfactant, (2) oil and (3) water are included at least, The said amphiphilic substance and surfactant are characterized in that the substantially whole quantity exists in a droplet interface.

In addition, the composition according to claim 1 is characterized in that the amount of interface between the amphiphilic material and the surfactant is 90% or more in terms of area ratio according to DSC.

The composition according to claim 3 is characterized in that the amphiphilic substance and the surfactant are selected from the ones in which the transition temperature of the gel formed in the amphiphilic substance-surfactant-water system is 60 ° C or higher.

Moreover, the composition of Claim 1 is characterized in that an emulsion particle diameter is 0.15 micrometer or less.

The composition of claim 5 is characterized in that an oil phase is blended in an amount of 1/2 or more with respect to the total amount of the amphoteric philic substance and the surfactant.

Moreover, the composition of Claim 6 is 0.2 weight% or more with respect to an aqueous phase in the total amount of an amphiphilic substance and surfactant.

In addition, the composition of claim 7 is characterized in that the amphiphilic material is made of higher alcohol and / or higher fatty acid having a carbon ring length of 16 or more.

The composition according to claim 8 is characterized in that the surfactant consists of a cationic surfactant or an anionic surfactant.

Hereinafter, the structure of this invention is demonstrated in detail again.

In the present invention, the amphiphilic substance and the surfactant which migrate to the characteristic aqueous phase-oil phase interface need to specifically form a gel in the amphiphilic substance-surfactant-water system. In particular, when emulsifying stability is taken into consideration, if the gel is α-type, its stability is good and the transition temperature of the gel is suitably 60 ° C or higher. The gel may be determined by the strong single peak of 21.4 ° in X-ray diffraction.

Thus, behenic acid and / or behenyl alcohol (both lipophilic substance) -behenic acid / potassium hydroxide fatty acid soap (surfactant) as a combination of an amphoteric lipophilic-surfactant which forms a gel in water and above room temperature. Or stearic acid and / or stearyl alcohol (both lipophilic substances) -stearic acid / potassium hydroxide fatty acid soap (surfactant), stearyl alcohol- (both lipophilic substances) -cetyl sulfate (surfactant), behenyl alcohol (both sides A combination of lipophilic) -behenyltrimethyl ammonium chloride (surfactant) and behenyl alcohol (both lipophilic) -stearyltrimethyl ammonium chloride (surfactant) is suitable. For example, emulsification stability can be further improved by using a combination of long carbon ring length and ring length such as behenic acid and stearic acid.

In addition, although it has an interfacial activity with the amphiphilic substance, it is hydrophobic in itself and does not have the same surfactant activity as that of the general surfactant, for example, higher fatty acids, higher aliphatic alcohols, monoglycerides, glycerol monoalkyl ethers, Monoalkylamines and compounds having a sterol skeleton (cholesterol, pitsterol) and the like.

The oil phase amount is 1/2 or more times, preferably the same amount or more, based on the total amount of the amphoteric lipophilic-surfactant.

If the amount of oil phase is less than half of the total amount of the amphoteric lipophilic-surfactant, the stability over time of the emulsified state tends to be deteriorated.

Moreover, emulsified particle diameter is 0,15 micrometers or less, Especially 0.10 micrometer or less is suitable.

If the particle diameter exceeds 0.15 mu m, there is a risk of creaming at low viscosity. The average particle diameter of the emulsion which can be used here is measured by the dynamic light scattering method, and specifically, it measured by NICOMP-270 (made by HIAC / ROYCO company).

In the oil-in-water emulsion composition according to the present invention, it is considered that the aqueous phase gels at the time of coating. Therefore, if the total amount of the amphiphilic substance and the surfactant is less than 0.2 with respect to the aqueous phase, gelation does not occur and a creamy feeling is used. There is a case that can not be obtained. In general, the amount of the amphiphilic-surfactant for forming the gel in the water phase is 0.2%, but a small amount of water is volatilized at the time of the painting, so even the amount of the cream can be obtained. More preferably, it is 0.5% or more. In the present invention, the oil phase component blended in the system may be any of liquid oil, solid oil, semi-solid oil, or poorly water-soluble substance. For example, avocado oil, camellia oil, turtle oil, macadamia nut oil, corn oil, Mink oil, olive oil, rapeseed oil, egg yolk oil, sesame oil, persian oil, wheat germ oil, sanda oil, castor oil, linseed oil, saffron oil, cottonseed oil, raw colostrum oil, perilla oil, soybean oil, peanut oil, tea seed oil, non-tree oil , Rice Bran Oil, Chinese Paulownia Oil, Japanese Paulownia Oil, Jojoba Oil, Embryo Oil, Triglycerin, Trioctane Glycerin, Triisopalmitin Glycerin, Cacao Oil, Palm Oil, Horse Oil, Palm Oil, Bovine Oil, Lamb Oil, Cured Oil, Solid oils such as palm kernel oil, pork oil, beef bone oil, waxy core oil, hardened oil, soda bone oil wax, hardened castor oil, beeswax, candela wax, cotton wax, carnova wax, bayberry wax, pewter, whale oil, ongtan wax, Rice rapeseed, ranol , Cabo Claw, Lanolin Acetate, Liquid Lanolin, Sugar Cane Lob, Lanolin Fatty Acid Isopropyl, Hexyl Laurinate, Reduced Lanolin, Jojo Barab, Hard Lanolin, Cerlab, Poelanolin Alcohol Ether, Poelanolin Alcohol Acetate, Lanolin Rab, such as fatty acid polyethylene glycol and pholine lanolin alcohol ether, hydrocarbons such as liquid paraffin, ozokerite, squalene, pristane, paraffin, sulcin, squalene, waserine and microcrystalline wax, isopropyl mysticin , Cetyl octanoate, octyldodecyl myristinate, isopropyl palmitic acid, butyl stearate, hexyl laurate, myristin acid myristyl, dodecyl oleate, dimethyl octanoate hexyldodecyl, cetyl lactate, myristyl, lanolin acetate Isocetyl stearate, isocetyl isostearate, cholesteryl 12-hydroxystearate, ethylene glycol di-2-ethylhexyl acid, dipentaery Tall fatty acid ester monoisostearic acid, N-alkylglycol, dicaflic acid neopentyl glycol, diisostearyl lingoic acid, glycerin di-2-heptyl undecanoic acid, tri-2-ethylhexyl trimethylolpropane, triisostearic acid, Trimethylolpropane, tetra-2-ethylhexyl pentaerythritol, tri-2-ethylhexane glycerin, triisostearic acid trimethylolpropane, cetyl-2-ethylhexanoate, 2-ethylhexyl palmitate, trimyristeric acid glycerin , Tri-2-heptyl undecanoic acid glyceride, himashi oil fatty acid methyl ester, oleic acid oil, cetostearyl alcohol, acetglyceride, palmitic acid-2-heptyl undecyl, adipic acid diisopropyl, N-lauroyl- L-glutamic acid-2-octyldodecyl ester, adipic acid-2-heptyl undecyl, ethyl laurate, sebatinic acid di-2-ethylhexyl, myristylic acid-2-hexyldodecyl, palmitic acid-2-hexyldodecyl Adipic acid-2-hexyl Synthetic esters such as dodecyl, diisopropyl sebatylate, 2-ethylhexyl coacetic acid, butyl acetic acid, butyl acetate, amine acetate, triethyl quenoic acid, lauric acid, myristic acid, palmitic acid, stearic acid, and behenic acid Higher aliphatic such as henyl) acid oleic acid, 12-hydroxystearic acid, undecylenic acid, turtle acid, lanolin fatty acid, isostearic acid, linoleic acid, linoleic acid, eicosapentaenoic acid, lauline alcohol, cetyl alcohol, stearyl alcohol , Beheryl alcohol, myristyl alcohol, oleyl alcohol, cetostearyl alcohol. Linear, branched chain alcohol dimethyl polysiloxane, methylphenyl polysiloxane, such as monostearyl glycerine ether (batyl alcohol), 2-decyltetradecinol, lanolin alcohol, cholesterol, hexyldecanol, isostearyl alcohol, octyldodecanol Cyclic polysiloxane amino modified silicone oil, such as cyclic polysiloxane, octamethylcyclo tetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, such as methylhydrodiene polysiloxane, epoxy modified silicone oil, epoxy, polyethyl modified silicone oil, 3D net structure such as polyether modified silicone oil, carboxy modified silicone oil, alcohol modified silicone oil, alkali modified silicone oil, ammonium modified silicone oil, fluorine modified silicone oil, trimethyl siloxy silicic acid, or silicone resin that can be formed, High Polymeric Dimethyl Polysiloxane, High Polymeric Methylphenylsiloxane, High Polymeric Methylvinylpolysiloxane Paulocarbon to Paulopolyether, vitamin A and its derivatives, vitamin D and its derivatives, vitamin E and its derivatives, vitamins such as silicone rubber, fouling ore decalin, fouling hexane, trifoulingo-nbutyl amine Vitamins such as K and its derivatives, sterols, natural and synthetic dyes, and the like, which are distinguished from liquid oils having a double melting point below room temperature and solid and semisolid oils having a melting point above room temperature.

Examples of the poorly water-soluble substances in water include vitamins such as ubiquinone and vitamin P, bactericides such as trichlorhexidine, trichlorocarbanilide and Imegalic acid D300, drugs such as dexamethasone acetate, and paraamide benzoic acid (hereinafter referred to as PABA), ultraviolet absorbers such as N and N-dimethyl PABA octyl ester, and preservatives such as paraben.

The emulsion composition of the present invention is an emulsifier which can give a strong cutting force to a mixed dispersion having the above essential ingredients even by a homomixer, for example, manton gourin, French press colloid and microfloodizer, ultrasonic emulsifier, etc. By the treatment, the transparency and stability can be improved.

Moreover, when using high pressure homogenizers, such as a manton gourin, a french press, and a micro flow dimer, it is preferable to emulsify under 1000 psi or more, More preferably, 3000 psi or more is the most suitable.

The emulsification treatment according to the present invention may be carried out in its entirety, or in some cases, a part thereof may be treated, and then it may be distilled with other compound such as water or polyhydric alcohol. Moreover, it is preferable to perform the temperature at the time of emulsification more than the transition temperature of the gel which the surfactant in a system and an amphoteric substance form with water.

About the emulsion composition of this invention, various components can be mix | blended in addition.

Among such components, as an aqueous phase component, for example, ethylene glycol, propylene glycol, 1,3-butylene glycol, dipropylene glycol, glycerin, diglycerin, triglycerine, tetraglycerin and other polyglycerol, glucose, maltose, maltitol , Sucrose, fructose, xylyltol, inositol, pentaerythritol, sorbitol, maltotriose, starch cracked sugar, starch cracked sugar reducing alcohol, and the like.

Examples of the water phase referred to herein include water-soluble active substances such as vitamin B group, vitamin C and its derivatives, panthenic acid and its derivatives, and vitamins such as biotin, sodium glutamate, arginine, aspartic acid, quenoic acid, and tartaric acid lactic acid. In addition to buffers, such as EDTA and chelating agents, such as EDTA, a ultraviolet absorber, a kind of various pigments, or 2 or more types of aqueous solution are mentioned.

EXAMPLE

Hereinafter, the present invention will be described in detail with reference to specific examples. In addition, this invention is not limited to a following example.

[Amount present in the oil droplet interface of both lipophilic substances and surfactant]

As described above, in the present invention, the amount of the surfactant and the amphiphilic substance in the oil droplet interface and the amount remaining in the water phase have a very significant effect on the aqueous solution properties during storage and the creamy texture during coating. Crazy

Therefore, the present inventors first prepared the oil-in-water emulsion composition of the following Comparative Examples 1, 2, 3 and Example 1, and examined the physical properties at the time of completion, the change according to the time, and the feeling of use.

In other words, the residual amount at the oil droplet interface of the amphoteric lipophilic substance and the surfactant can be estimated by the change of the previous peak area of the gel.

Therefore, the temperature of the peak of the endothermic peak observed in the DSC temperature rising curve obtained by using a differential scanning meter (DSC), specifically DSC120 (manufactured by Seiko Electronics Co., Ltd.) was measured as the transition temperature.

TABLE 1

[quite]

Comparative Example 1; (1)-(4) are stirred and mixed at 80 degreeC. The mixed solution of (6) to (9) was heated and dissolved at 70 ° C while stirring, and mixed with a homomixer at 80 ° C.

Comparative Examples 2 and 3 and Example 1; (1)-(5) are stirred and mixed at 80 degreeC. The mixed solution of (6) to (8) was stirred while being heated and dissolved at 70 ° C, and Comparative Example 2 was emulsified with a homomixer at 80 ° C, followed by stirring and mixing (9), and Comparative Example 3 had a pressure of 500 psi. After emulsifying with high pressure homogenizer under 0, stirring and mixing (P), Example 1 emulsifying with high pressure homogenizer under pressure of 7000 psi and stirring mixing (9), respectively, Another sample was obtained.

4 shows the change in the DSC temperature rise curve according to the refinement of the emulsion.

In the same figure, the comparative example 1 is a system except oil, but the single transition peak is observed at 75 degreeC. Since the emulsion is not formed in the oil-free system, the amphiphilic substance and the surfactant form a gel in the water phase, and this state is shown in the same figure. Comparative Examples 2, 3 and Example 1 were formulated with oil, and the emulsion particle diameters were 1 to 10 µm, 0.24 µm and 0.07 µm, respectively. With the refinement of the emulsified particles, the DSC curve decreases the peak at the high temperature side, and in Example 1, only the lowest temperature peak and the particle diameter decreases. It is suggested that the active agent shifts to the interface as the surface area of the emulsion increases and the amount of the nutrient in the water phase decreases.

In this case, the average particle diameter of the emulsion was measured by microscopic observation when the particle diameter was 1 µm or more. When the average particle diameter was 1 탆 or less, the measurement was performed by dynamic light scattering method, and specifically, NICOMP-270 (manufactured by HYAC / ROYCO) was used.

Since the DOS curve of Example 1 having an average particle diameter of 0.07 μm is a single transition peak at 63 ° C., both of the amphiphilic material and the surfactant show a state in which most of them move to the interface of the emulsion. The increase in the division of the peak on the high temperature side with this increase indicates that the amount of the gel constituent material in the water phase, that is, the amount of the amphoteric philic material and the surfactant is increased. In order to ensure the appearance of the aqueous phase and the stability at the merchandise level, it is preferable that the DSC curve is a low temperature side peak, but the area of the high temperature side peak may be about 10% of the total.

The emulsion compositions according to Comparative Examples 1, 2, 3 and Example 1 prepared as described above had the following physical properties and usability.

TABLE 2

As can be seen in Table 2, Comparative Example 2 can obtain a feeling of use of the cream, but the physical properties of the aqueous phase is not obtained because of the high viscosity. In Comparative Example 3, the transparency is increased, the viscosity is lowered, and the physical properties of the aqueous phase are closer, but stability is obtained from the presence of the amphiphilic substance and the surfactant in the water phase (deposition of sediment over time, turbidity rise, creaming, etc.). Deteriorates.

On the contrary, Example 1 had high transparency at low viscosity, had physical properties in aqueous solution, had good stability, and had excellent creamy feeling when applied.

[Emulsion particle diameter]

Next, the present inventors examined the correlation between the emulsion particle diameter, stability, and appearance of the oily phase of the present invention.

That is, when the emulsion phase diameter of the oily phase is large in the inner phase of the emulsion composition according to the present invention, the physical properties of the aqueous phase may be damaged by the increase in turbidity and the viscosity, and the stability (creaming, etc.) may be deteriorated. have.

Thus, the inventors of the present invention have prepared an oil-in-water emulsion composition suitable as an external preparation for skin based on the following formulation. At this time, emulsification was carried out using manton green, but the cutting force was adjusted to adjust the diameter of each emulsified particle.

(1) Behenyl Alcohol 1.0%

(2) stearyl alcohol 0.5%

(3) 0.5% behenic acid

(4) 0.5% stearic acid

(5) 5.0% of liquid paraffin

(6) 0.15% potassium hydroxide

(7) 1,3-butylene glycol 10.0%

(8) 10.0% of ion-exchanged water

(9) residual amount of ion exchange water

[quite]

(1)-(5) are stirred and mixed at 80 degreeC. This was mixed while stirring the mixture of (6) to (8) by heating and melting at 80 ° C, followed by stirring and mixing (9) during emulsification using a high pressure homogenizer at 80 ° C under a homomixer and various pressures. And different samples of respective emulsified particle diameters were obtained.

In the above formulation, fatty acid soap is made of behenic acid, stearic acid, and potassium hydroxide, which functions as a surfactant. It also functions as an amphiphilic substance of unneutralized behenic acid, stearic acid, behenyl alcohol and stearyl alcohol.

The results are shown in Table 3 below.

TABLE 3

Stability: The stability after one month was visually evaluated.

As can be seen in Table 3, the emulsion particle diameter is about 0.1㎛, both stability and appearance are very good. When the emulsified particle diameter is about 15 mu m, there is no problem in stability, but the appearance is almost white.

If the particle size exceeds 0.15 占 퐉, the stability deteriorates (creaming), and the appearance tends to become cloudy.

Therefore, it is understood that the suitable emulsified particle diameter in the emulsion composition according to the present invention is 0.15 µm or less, particularly 0.10 µm or less.

[Ratio of total amount of both lipophilic substances and surfactant and amount of oil]

Next, the present inventors examined the ratio of the total amount of the amphiphilic substance and the surfactant and the amount of the oil. In other words, in the emulsion composition according to the present invention as described above, it is necessary to transfer substantially the entire amount of the amphiphilic substance and the surfactant to the oil droplet crab surface.

There is a limit to miniaturization of the emulsified particles, and the amount of the oil is relatively small, the interfacial electric charge becomes relatively small. Therefore, it is difficult to sufficiently transfer the amphiphilic substance and the surfactant to the interface, and as a result, there is a fear that the gel component remains and the stability of the emulsion composition is significantly deteriorated.

Therefore, based on the following prescription, the oil-in-water emulsion composition suitable as a skin external preparation was manufactured, and the emulsion particle diameter and stability with time were examined.

TABLE 4

[quite]

(1) (2) (4) is stirred and mixed at 80 ° C. This was mixed while stirring the solution of (3) (5) (6) by heating and melting at 80 ° C, and emulsified by distilling the high pressure homogenizer under a pressure of 5000psi at 80 ° C, followed by stirring and mixing (7). The sample was obtained.

As can be seen from Table 4, when the amount of the liquid paraffin in the oil phase changes from 2.0 to 10.0% with respect to the total amount (2.5%) of both lipophilic substances in the surfactant, the smaller the amount of the liquid paraffin, the smaller the emulsified particle diameter, but the time It is understood that the stability is rather reduced, and the ratio of the total amount of the surfactant amphiphilic material and the oil phase is 1 / 0.5 or more, preferably 1/1 or more.

In the following, the present inventors examined the total amount of both the lipophilic substance and the surfactant and the feeling of creamy feeling, and thus, the following tests were conducted.

TABLE 5

[quite]

(1) (2) (4) (5) is stirred and mixed at 70 ° C. This was mixed while stirring the mixture of (3) (6) (7) by heating and melting at 70 ° C, and emulsified using a high pressure homogenizer at 5000 psi at 70 ° C, followed by stirring and mixing (8). The sample was obtained.

As can be seen from Table 5, when the total amount of both surfactants is 2.5 to 0.15% with respect to the oil phase (5%), the less the total amount of surfactant amphiphilic substances is, the more impaired the creamy feel when applied. It is understood that the total amount is 0.2% or more, preferably 0.5% or more.

[Composition of Both Amphiphilic Substances and Surfactants]

Next, the present inventors examined the composition of surfactant and an amphoteric substance.

In other words, the surfactant and amphoteric material used in the present invention is a surfactant amphiphilic water-based, it is necessary to form a gel in the temperature range of the room temperature at least at the freezing point of the water phase, preferably the transition temperature of the gel is 60 ℃ That's it.

In general, the transition temperature of the gel formed by the aqueous surfactant amphiphilic material is 10 to 20 ° C. higher than the temperature at which the gel is formed (starting flow). It can be considered that a gel can be formed.

Therefore, the following basic composition was examined for the change of properties according to the combination of surfactant and amphoteric material.

Emulsion Composition

(1) floating paraffin 5.0

(2) Surfactant 1.0

(3) Amphiphilic Substances 1.5

(4) 1,3-BG 10.0

(5) ion exchange water 20.0

(6) residual amount of ion exchange water

Gel

(1) Surfactant 1.0

(2) Amphiphilic Substances 1.5

(3) residual amount of ion exchange water

[quite]

Sulfur composition: (1) (3) is stirred and mixed at 70 to 80 ° C. This is added with emulsification while stirring the liquid mixture of (2) (4) (5) at 80 degreeC by heat-dissolving. The solution was emulsified using a high pressure homogenizer at 70 to 80 ° C. under a pressure of 7000 psi, and then (6) was stirred and mixed to obtain a sample.

Gel: Stir and mix (2) at 80 ° C. This was added while stirring and mixing the liquid mixture of (1) (3) at 80 degreeC, and it processed by the homomixer to make a sample.

The results are shown in Tables 6 to 8.

In each table, when there are description of two types of surfactant or an amphiphilic substance, they are mix | blended in the composition of 1: 1 by weight ratio, respectively.

TABLE 6

TABLE 7

TABLE 8

Evaluation of stability: ○ good

△ rise in turbidity or formation of aggregates

× solidification

As can be seen from Tables 6 to 8, the combination of the surfactant and the amphoteric material has a good stability when the combination of the gel transition temperature is high and the combination having a different carbon ring length is very good. have.

The specific example of the composition concerning this invention is shown below.

Example 1 Serum

(1) behenyl alcohol 2.0

(2) behenic acid 1.5

(3) floating paraffin 7.0

(4) Vitamin E Acetate 0.5

(5) Butylparaben 0.2

(6) KOH 0.15

(7) ethanol 5.0

(8) dynamite glycerin 5.0

(9) flavoring 0.05

(10) ion exchange water 15.0

(11) trisodium edetic acid 0.01

(12) 2-hydroxy-4-methoxy benzophenone-5-sulfonate 0.05

(13) residual amount of ion exchange water

(1)-(5) are stirred and mixed at 70 degreeC. This is added and emulsified while stirring the mixture liquid of (6)-(10) by heat-dissolving at 70 degreeC. The emulsion was emulsified using a high pressure homogenizer at 75 ° C. under a pressure of 6000 psi, and then stirred and mixed with (11) to (13) to obtain a semitransparent low viscosity cosmetic liquid. The average particle diameter of the emulsion of the obtained cosmetic liquid was measured by the dynamic light scattering method, and the result was 0.05 µm and the viscosity was 10 cps. As it was actually used, it was able to obtain a creamy feeling as it was applied.

Example 2 Whitening Solution

(1) behenyl alcohol 1.5

(2) behenic acid 1.0

(3) floating paraffin 5.0

(4) Vitamin E Acetate 0.5

(5) Butylparaben 0.2

(6) KOH 0.13

(7) 1,3-butylene glycol 7.0

(8) Dynamite Glycerin 8.0

(9) flavoring 0.05

(10) ion exchange water 15.0

11 Arbutin 3.0

(12) remaining amount of ion exchange water

(1)-(5) are stirred and mixed at 70 degreeC. This is added and emulsified while stirring the mixture liquid of (6)-(10) by heat-dissolving at 70 degreeC. The emulsion was emulsified using a high pressure homogenizer at 75 ° C. under a pressure of 8000 psi, and then the mixed solution of (11) to (12) was stirred and mixed to obtain a translucent, low viscosity cosmetic liquid. When the average particle diameter of the emulsion of the obtained cosmetic liquid was measured, 0.04 micrometer and viscosity were 10cps. As it was actually used, the cream-like feeling was obtained according to the application.

Example 3 Serum

(1) behenyl alcohol 2.0

(2) stearyl alcohol 1.5

(3) behenic acid 1.0

(4) stearic acid 1.0

(5) liquid paraffin 8.0

(6) Waselin 2.0

(7) Vitamin E Acetate 0.5

(8) Butylparaben 0.2

(9) KOH 0.2

(10) 1,3-butylene glycol 7.0

(11) dynamite glycerin 10.0

12.Fragrance 0.05

(14) ion exchange water 40.0

(15) remaining amount of ion exchange water

(1)-(8) are stirred and mixed at 70 degreeC. This is added and emulsified while stirring the liquid mixture of (9)-(14) at the temperature which melt | dissolved at 70 degreeC. The emulsion was emulsified using a high pressure homogenizer at 80 ° C. under a pressure of 4000 psi, and then stirred and mixed (15) to obtain a translucent, low viscosity cosmetic liquid. When the average particle diameter of the emulsion of the obtained cosmetic liquid was measured by the dynamic light scattering method, 0.07 micrometer and the viscosity were 25 cps. As it was actually used, the cream-like feeling was obtained according to the application.

Example 4 Hair Treatment

(1) behenyl alcohol 1.5

(2) stearyl alcohol 0.3

(3) Dimethylsilicon (20cps) 10.0

(4) behenyltrimethylammonium chloride 1.0

(5) 1,3-butylene glycol 5.0

(6) dynamite glycerin 10.0

(7) fragrance 0.05

(8) Methylparaben 0.2

(9) residual amount of ion exchange water

(1)-(3) are mixed and heated at 70 degreeC. This is added and emulsified while stirring the mixture liquid of (4)-(9) by heat-dissolving at 70 degreeC. This emulsion was emulsified using a high pressure homogenizer at 75 ° C. under a pressure of 8000 psi atmosphere to obtain a hair treatment agent having a transparent viscosity.

The average particle diameter of the obtained emulsion of hair treatment agent was measured by the dynamic light scattering method. As a result, 0.12 µm and the viscosity were 20 cps. As it was actually used, the cream-like feeling was obtained according to the application.

Example 5 Senscreen

(1) Behenyl Alcohol 1.0

(2) stearyl alcohol 0.5

(3) behenic acid 0.5

(4) stearic acid 0.5

(5) Decaffeinated Neopentylglycol 5.0

(6) Glycerin Mono-2-ethylhexanoyl- 1.0

Diparamethoxy cinnamate

(8) Butylparaben 0.2

(9) KOH 0.2

(10) 1,3-butylene glycol 7.0

(11) dynamite glycerin 8.0

12.Fragrance 0.05

(13) ion exchange water 15.0

(14) remaining amount of ion exchange water

(1)-(7) are mixed and heated at 70 degreeC. This is added and emulsified while stirring the mixed liquid of (8)-(12) at the temperature which melt | dissolved at 70 degreeC. This emulsion was emulsified using a high pressure homogenizer at 70 ° C. under a pressure of 6000 psi, and then stirred and mixed with (13) to obtain a translucent, low viscosity, sensitizer.

The average particle diameter of the obtained emulsion made of the sensitive screen was measured by the dynamic light scattering method. As a result, the viscosity was 15 cps. As it was actually used, the cream-like feeling was obtained according to the application.

As described above, in this embodiment, the oil-in-water emulsion composition has relatively high transparency, low viscosity, and aqueous solution properties in its preservation state, and a creamy feeling can be obtained when it is used during application. Become.

As described above, according to the present oil-in-water emulsion composition, the substantial amount of the amphoteric amphiphilic substance and the surfactant are present at the interface between the oil phase and the water phase, thereby simultaneously imparting the physical properties of the aqueous phase and the creamy feeling of use. It becomes possible.

Claims (6)

Amphiphilic substance-surfactant-Amphiphilic substance selected from among those capable of forming a gel at room temperature or higher in an aqueous system, including surfactant, oil and water, and the presence of an interface between the amphiphilic substance and the surfactant An oil-in-water emulsion composition characterized in that the amount is 90% or more by the peak area ratio by DSC and the emulsified particle diameter is 0.15 µm or less. The oil-in-water emulsion composition according to claim 1, wherein the amphiphilic substance and the surfactant are selected from those having a transition temperature of a gel formed in the amphiphilic substance-surfactant-water system being 60 ° C or higher. The oil-in-water emulsion composition according to claim 1 or 2, wherein an oil phase is blended in an amount of 1/2 or more with respect to the total amount of the amphiphilic substance and the surfactant. The oil-in-water emulsion composition of Claim 1 or 2 whose total amount of an amphiphilic substance and surfactant is 0.2 weight% or more with respect to an aqueous phase. The oil-in-water emulsified composition according to claim 1 or 2, wherein the amphiphilic material comprises a higher alcohol and / or a higher fatty acid having a carbon ring length of 16 or more. The oil-in-water emulsion composition according to claim 1 or 2, wherein the surfactant comprises a cationic surfactant or an anionic surfactant.