KR100258581B1 - 3-hydroxy-3-methylglutaryl coa reductase inhibitorycomposition comprising vitamin c and citrus peelextract - Google Patents
3-hydroxy-3-methylglutaryl coa reductase inhibitorycomposition comprising vitamin c and citrus peelextract Download PDFInfo
- Publication number
- KR100258581B1 KR100258581B1 KR1019990045735A KR19990045735A KR100258581B1 KR 100258581 B1 KR100258581 B1 KR 100258581B1 KR 1019990045735 A KR1019990045735 A KR 1019990045735A KR 19990045735 A KR19990045735 A KR 19990045735A KR 100258581 B1 KR100258581 B1 KR 100258581B1
- Authority
- KR
- South Korea
- Prior art keywords
- extract
- hydroxy
- vitamin
- coa
- methylglutaryl coa
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
PURPOSE: Composites for inhibiting 3-Hydroxy-3-methylglutaryl CoA(HMG-CoA) reductase activity are provided to drop blood cholesterol for the prevention and the treatment of high cholesterol by containing vitamin C and orange peel extract, vitamin C, hesperidin and naringin. CONSTITUTION: Orange peels are washed with water and dried at room temperature in the shade. Water or 95% ethanol is added to the dried orange peels to extract active substances at 5-140deg.C. The extract is injected to a blood cholesterol patient as much as 1-5g/1kg/day. The extract is added to foods or beverages for to impeding 3-Hydroxy-3-methylglutaryl CoA(HMG-CoA) reductase activity, and drops blood cholesterol. The composites of the extract are varied by reaction time, reaction temperature, alcohol concentration, orange type and ripe rate.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019970055581A KR100254908B1 (en) | 1997-10-28 | 1997-10-28 | 3-hydroxy-3-methylglutaryl coa reductase inhibitory composition comprising vitamin c and citrus peel extract |
Publications (1)
Publication Number | Publication Date |
---|---|
KR100258581B1 true KR100258581B1 (en) | 2000-05-15 |
Family
ID=19523581
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019970055581A KR100254908B1 (en) | 1997-10-28 | 1997-10-28 | 3-hydroxy-3-methylglutaryl coa reductase inhibitory composition comprising vitamin c and citrus peel extract |
KR1019990045735A KR100258581B1 (en) | 1997-10-28 | 1999-10-21 | 3-hydroxy-3-methylglutaryl coa reductase inhibitorycomposition comprising vitamin c and citrus peelextract |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019970055581A KR100254908B1 (en) | 1997-10-28 | 1997-10-28 | 3-hydroxy-3-methylglutaryl coa reductase inhibitory composition comprising vitamin c and citrus peel extract |
Country Status (1)
Country | Link |
---|---|
KR (2) | KR100254908B1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030002214A (en) * | 2001-06-30 | 2003-01-08 | 알앤엘생명과학주식회사 | Compositions for preventing and treating brain diseases |
KR100702567B1 (en) * | 2004-06-09 | 2007-04-02 | 퓨리메드 주식회사 | Poncirus trifoliata extract for recovering after myocardial infraction shock and pharmaceutical composition and health food containing the same |
KR20100133133A (en) * | 2009-06-11 | 2010-12-21 | (주)바이오뉴트리젠 | A composition containing the extract of citrus peel, persimmon, lycium chinense and buckwheat leaf for preventing or improving hyperlipidemia and manufacturing method thereof |
CN114149390B (en) * | 2021-12-14 | 2023-10-27 | 梅州市珍宝金柚实业有限公司 | Vitamin C extraction method |
-
1997
- 1997-10-28 KR KR1019970055581A patent/KR100254908B1/en not_active IP Right Cessation
-
1999
- 1999-10-21 KR KR1019990045735A patent/KR100258581B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR100254908B1 (en) | 2000-05-01 |
KR19990034092A (en) | 1999-05-15 |
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A201 | Request for examination | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20120314 Year of fee payment: 13 |
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LAPS | Lapse due to unpaid annual fee |