KR100214908B1 - A reduction method for substituted 5-methylene-thiazolidinediones - Google Patents

A reduction method for substituted 5-methylene-thiazolidinediones Download PDF

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Publication number
KR100214908B1
KR100214908B1 KR1019940702123A KR19940702123A KR100214908B1 KR 100214908 B1 KR100214908 B1 KR 100214908B1 KR 1019940702123 A KR1019940702123 A KR 1019940702123A KR 19940702123 A KR19940702123 A KR 19940702123A KR 100214908 B1 KR100214908 B1 KR 100214908B1
Authority
KR
South Korea
Prior art keywords
thiazolidinediones
methylene
substituted
reduction method
reduction
Prior art date
Application number
KR1019940702123A
Other languages
English (en)
Inventor
Joel Edward Huber
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of KR100214908B1 publication Critical patent/KR100214908B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
KR1019940702123A 1991-12-20 1994-06-18 A reduction method for substituted 5-methylene-thiazolidinediones KR100214908B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81110391A 1991-12-20 1991-12-20
PCT/US1992/010329 WO1993013095A1 (en) 1991-12-20 1992-12-04 A reduction method for substituted 5-methylene-thiazolidinediones

Publications (1)

Publication Number Publication Date
KR100214908B1 true KR100214908B1 (en) 1999-08-02

Family

ID=25205568

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940702123A KR100214908B1 (en) 1991-12-20 1994-06-18 A reduction method for substituted 5-methylene-thiazolidinediones

Country Status (7)

Country Link
US (1) US5585495A (ko)
EP (1) EP0618915A1 (ko)
JP (1) JP2766730B2 (ko)
KR (1) KR100214908B1 (ko)
AU (1) AU3231093A (ko)
CA (1) CA2122712C (ko)
WO (1) WO1993013095A1 (ko)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6191169B1 (en) * 1992-08-28 2001-02-20 City Of Hope Human leukocyte 12-lipoxygenase and its role in the pathogenesis of disease states
AU774839B2 (en) * 1997-02-18 2004-07-08 Smithkline Beecham Plc Process for the preparation of substituted thiazolidinedione
US6632947B2 (en) 1997-02-18 2003-10-14 Smithkline Beecham Plc Process for the preparation of substituted thiazolidinedione
UY24886A1 (es) * 1997-02-18 2001-08-27 Smithkline Beecham Plc Tiazolidindiona
DE19711616A1 (de) 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Verbessertes Verfahren zur Herstellung von Thiazolidindionen
GB9723295D0 (en) 1997-11-04 1998-01-07 Smithkline Beecham Plc Novel process
US7091359B2 (en) 1997-11-04 2006-08-15 Smithkline Beecham Plc Process for the preparation of thiazolidinedione derivatives
US7105552B2 (en) * 1998-05-08 2006-09-12 Theracos, Inc. Heterocyclic analogs of diphenylethylene compounds
AU2001274502A1 (en) * 2000-06-14 2001-12-24 Kyorin Pharmaceutical Co. Ltd. Process for the preparation of thiazolidinedione derivatives
FR2820742B1 (fr) * 2001-02-14 2005-03-11 Ppg Sipsy Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine
US7135485B2 (en) 2001-09-28 2006-11-14 Teva Pharmaceutical Industries Ltd. Pioglitazone hydrochloride
US20050187258A1 (en) * 2001-12-20 2005-08-25 Ben-Zion Dolitzky Hydrogenation of precursors to thiazolidinedione antihyperglycemics
WO2003079975A2 (en) 2002-03-19 2003-10-02 Bristol-Myers Squibb Company Process for the manufacture of optically active 3-substituted lactams by asymmetric hydrogenation of 3-alkylidenelactams
WO2004024059A2 (en) * 2002-09-12 2004-03-25 Themis Laboratories Private Limited, Improved process for preparation of thiazolidinedione derivatives
WO2005073227A2 (en) * 2004-01-28 2005-08-11 Usv Limited A process for the preparation of 5-[4-[2-[n-methyl-n-(2-pyridyl) amino] ethoxy] phenyl methyl] thiazolidine-2, 4-dione maleate
CZ297266B6 (cs) * 2004-09-10 2006-10-11 Zentiva, A. S. Zpusob prípravy rosiglitazonu
US20060089387A1 (en) * 2004-10-26 2006-04-27 Le Huang Stabilized pharmaceutical composition comprising antidiabetic agent
WO2008010235A2 (en) * 2006-07-19 2008-01-24 Torrent Pharmaceuticals Limited An improved process for the preparation of donepezil
US20090118514A1 (en) * 2007-11-06 2009-05-07 Raghupathi Reddy Anumula Processes for preparing pioglitazone and its pharmaceutically acceptable salts
WO2009104200A1 (en) * 2008-02-21 2009-08-27 Biocon Limited A method for preparation of thiazolidinedione derivatives
AR081268A1 (es) * 2010-06-02 2012-07-18 Cardiolynx Ag Derivados de nitrato de pioglitazona
WO2012153312A1 (en) 2011-05-11 2012-11-15 Ranbaxy Laboratories Limited Process for the purification of pioglitazone

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4812570A (en) * 1986-07-24 1989-03-14 Takeda Chemical Industries, Ltd. Method for producing thiazolidinedione derivatives
US5061717A (en) * 1988-03-08 1991-10-29 Pfizer Inc. Thiazolidinedione hypoglycemic agents

Also Published As

Publication number Publication date
CA2122712A1 (en) 1993-07-08
US5585495A (en) 1996-12-17
CA2122712C (en) 1999-09-21
EP0618915A1 (en) 1994-10-12
AU3231093A (en) 1993-07-28
JPH07502530A (ja) 1995-03-16
WO1993013095A1 (en) 1993-07-08
JP2766730B2 (ja) 1998-06-18

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