JPWO2024019137A1 - - Google Patents
Info
- Publication number
- JPWO2024019137A1 JPWO2024019137A1 JP2024535147A JP2024535147A JPWO2024019137A1 JP WO2024019137 A1 JPWO2024019137 A1 JP WO2024019137A1 JP 2024535147 A JP2024535147 A JP 2024535147A JP 2024535147 A JP2024535147 A JP 2024535147A JP WO2024019137 A1 JPWO2024019137 A1 JP WO2024019137A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C07H1/02—Phosphorylation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/067—Pyrimidine radicals with ribosyl as the saccharide radical
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022117422 | 2022-07-22 | ||
| PCT/JP2023/026733 WO2024019137A1 (ja) | 2022-07-22 | 2023-07-21 | オリゴヌクレオチドの製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPWO2024019137A1 true JPWO2024019137A1 (https=) | 2024-01-25 |
Family
ID=89617881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024535147A Pending JPWO2024019137A1 (https=) | 2022-07-22 | 2023-07-21 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP4559925A1 (https=) |
| JP (1) | JPWO2024019137A1 (https=) |
| KR (1) | KR20250042734A (https=) |
| CN (1) | CN119403816A (https=) |
| WO (1) | WO2024019137A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12416020B2 (en) | 2024-02-20 | 2025-09-16 | Wyvern Pharmaceuticals Inc. | Plasmid encoding a TLR3 and Fc fusion protein |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6077709A (en) | 1998-09-29 | 2000-06-20 | Isis Pharmaceuticals Inc. | Antisense modulation of Survivin expression |
| US6887990B1 (en) | 1999-02-05 | 2005-05-03 | Amersham Biosciences Corp | Method for deprotecting oligonucleotides |
| US6261840B1 (en) | 2000-01-18 | 2001-07-17 | Isis Pharmaceuticals, Inc. | Antisense modulation of PTP1B expression |
| AU2005275801B2 (en) | 2004-08-26 | 2012-05-10 | Nippon Shinyaku Co., Ltd. | Phosphoramidite compound and method for producing oligo-RNA |
| ES2526295T5 (es) | 2006-10-18 | 2021-05-04 | Ionis Pharmaceuticals Inc | Compuestos antisentido |
| MX370398B (es) | 2011-08-25 | 2019-12-11 | Bonac Corp | Compuesto de glicosido, metodo para producir tioeter, eter, metodo para producir eter, metodo para producir un compuesto de glicosido, metodo para producir acido nucleico. |
| DK2951191T3 (en) * | 2013-01-31 | 2019-01-14 | Ionis Pharmaceuticals Inc | PROCEDURE FOR MANUFACTURING OLIGOMERIC COMPOUNDS USING MODIFIED CLUTCH PROTOCOLS |
| WO2015164693A1 (en) * | 2014-04-24 | 2015-10-29 | Isis Pharmaceuticals, Inc. | Oligomeric compounds comprising alpha-beta-constrained nucleic acid |
| CA2969619A1 (en) | 2014-12-03 | 2016-06-09 | Agilent Technologies, Inc. | Guide rna with chemical modifications |
| BR112020005230A2 (pt) | 2017-09-19 | 2020-09-24 | Alnylam Pharmaceuticals, Inc. | composições e métodos para o tratamento da amiloidose mediada por transtiretina (ttr) |
| US11897911B2 (en) | 2018-03-07 | 2024-02-13 | Sanofi | Nucleotide precursors, nucleotide analogs and oligomeric compounds containing the same |
| KR102670605B1 (ko) | 2018-04-24 | 2024-05-29 | 스미또모 가가꾸 가부시끼가이샤 | 아미다이트 화합물 및 그 화합물을 사용한 폴리뉴클레오티드의 제조 방법 |
| EP3950698A4 (en) * | 2019-03-28 | 2023-01-25 | Ajinomoto Co., Inc. | METHOD OF PREPARING AN OLIGONUCLEOTIDE WITH PHOSPHOROTHIOATE SITE |
| CN112007040B (zh) | 2019-05-31 | 2024-01-30 | 苏州瑞博生物技术股份有限公司 | 用于治疗乙型病毒性肝炎的联合用药物 |
| KR20220062517A (ko) * | 2019-08-15 | 2022-05-17 | 아이오니스 파마수티컬즈, 인코포레이티드 | 결합 변형된 올리고머 화합물 및 이의 용도 |
| JP7804434B2 (ja) | 2021-01-29 | 2026-01-22 | 日東電工株式会社 | 光学用粘着テープ |
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2023
- 2023-07-21 EP EP23843060.7A patent/EP4559925A1/en active Pending
- 2023-07-21 CN CN202380048887.9A patent/CN119403816A/zh active Pending
- 2023-07-21 JP JP2024535147A patent/JPWO2024019137A1/ja active Pending
- 2023-07-21 KR KR1020257000384A patent/KR20250042734A/ko active Pending
- 2023-07-21 WO PCT/JP2023/026733 patent/WO2024019137A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN119403816A (zh) | 2025-02-07 |
| WO2024019137A1 (ja) | 2024-01-25 |
| EP4559925A1 (en) | 2025-05-28 |
| KR20250042734A (ko) | 2025-03-27 |