JPWO2023190176A5 - - Google Patents

Info

Publication number
JPWO2023190176A5
JPWO2023190176A5 JP2024512364A JP2024512364A JPWO2023190176A5 JP WO2023190176 A5 JPWO2023190176 A5 JP WO2023190176A5 JP 2024512364 A JP2024512364 A JP 2024512364A JP 2024512364 A JP2024512364 A JP 2024512364A JP WO2023190176 A5 JPWO2023190176 A5 JP WO2023190176A5
Authority
JP
Japan
Prior art keywords
glycero
formula
carbon atoms
group
phosphoglycerol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024512364A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2023190176A1 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2023/011850 external-priority patent/WO2023190176A1/ja
Publication of JPWO2023190176A1 publication Critical patent/JPWO2023190176A1/ja
Publication of JPWO2023190176A5 publication Critical patent/JPWO2023190176A5/ja
Pending legal-status Critical Current

Links

JP2024512364A 2022-03-28 2023-03-24 Pending JPWO2023190176A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2022051918 2022-03-28
PCT/JP2023/011850 WO2023190176A1 (ja) 2022-03-28 2023-03-24 脾臓組織へ核酸を送達するための脂質ナノ粒子およびこれを用いて脾臓組織へ核酸を送達する方法

Publications (2)

Publication Number Publication Date
JPWO2023190176A1 JPWO2023190176A1 (https=) 2023-10-05
JPWO2023190176A5 true JPWO2023190176A5 (https=) 2026-03-19

Family

ID=88201471

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024512364A Pending JPWO2023190176A1 (https=) 2022-03-28 2023-03-24

Country Status (6)

Country Link
EP (1) EP4501360A4 (https=)
JP (1) JPWO2023190176A1 (https=)
KR (1) KR20240163154A (https=)
CN (1) CN118973614A (https=)
CA (1) CA3247039A1 (https=)
WO (1) WO2023190176A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117778533B (zh) * 2023-12-30 2025-01-07 北京剂泰医药科技有限公司 核酸脂质纳米颗粒复合物中核酸的定量检测方法
CN118949071A (zh) * 2024-08-02 2024-11-15 中国科学院动物研究所 一种掺杂金属离子佐剂的脾脏靶向mRNA疫苗及其制备方法与应用
CN120757505B (zh) * 2025-09-08 2025-11-21 联合钠米(天津)科技有限公司 一种二烃基咪唑仿生型脂质化合物及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2702103A1 (en) * 2007-10-12 2009-04-16 Novosom Ag Improvements in or relating to amphotaric liposomes comprising neutral lipids
JP6093710B2 (ja) 2011-11-18 2017-03-08 日油株式会社 細胞内動態を改善したカチオン性脂質
JP6682856B2 (ja) 2015-01-30 2020-04-15 株式会社三洋物産 遊技機
WO2018237369A2 (en) * 2017-06-23 2018-12-27 Vical Incorporated Lipid nanoparticle (lnp)-mediated delivery of a crispr-expressing plasmid dna for treating chronic hepatitis b virus infection
WO2019188867A1 (ja) 2018-03-27 2019-10-03 日油株式会社 細胞内動態を改善した新規カチオン性脂質
MA55219A (fr) * 2019-03-06 2022-01-12 Generation Bio Co Nanoparticules lipidiques non actives avec adn dépourvu de capside, non viral
JP7700101B2 (ja) * 2019-09-06 2025-06-30 ジェネレーション バイオ カンパニー 閉端dnaおよび切断可能脂質を含む脂質ナノ粒子組成物ならびにそれらの使用方法
WO2021060440A1 (ja) * 2019-09-26 2021-04-01 日油株式会社 脂質ナノ粒子の凍結乾燥組成物
IL296763B2 (en) 2020-03-27 2026-04-01 Generation Bio Co New lipids and their nanoparticle compositions

Similar Documents

Publication Publication Date Title
JPWO2023190176A5 (https=)
Heyes et al. Synthesis and characterization of novel poly (ethylene glycol)-lipid conjugates suitable for use in drug delivery
USRE45195E1 (en) Compositions and methods for enhancing contrast in imaging
JP4885715B2 (ja) イリノテカン製剤
CA2739822A1 (en) Liposomal systems comprising sphingomyelin
CN108024960A (zh) 含有阴离子药物的药物组合物及其制备方法
US20150283077A1 (en) Controlled release hydrogels
AU2003270102B2 (en) Non-vesicular cationic lipid formulations
US20120003159A1 (en) Compositions and methods for enhancing contrast in imaging
JP2004527585A (ja) 脂質−ポリマー結合体
CN113908288A (zh) 一种mRNA递送系统及其制备方法和应用
JP5142313B2 (ja) ポリサルコシン誘導体及びこれを膜構成成分とする薬物担体
KR102911928B1 (ko) 신규 이온화 가능한 지질 및 이를 포함하는 지질나노입자
JP4833836B2 (ja) リポソーム製剤
Seo et al. Positron emission tomography imaging of the stability of Cu-64 labeled dipalmitoyl and distearoyl lipids in liposomes
EP1399191A2 (en) Cell penetrating therapeutic agents
CA2595485A1 (en) Liposomal compositions for parenteral delivery of statins
KR20140036338A (ko) 표적지향형 난용성 약물 전달체
JPWO2005021012A1 (ja) ゲムシタビン封入薬剤担体
WO2019161325A1 (en) Radiation-triggered liposomes
JP4791067B2 (ja) リポソーム製剤の製造方法
JPWO2023054241A5 (https=)
Nardo et al. In vivo assessment of triazine lipid nanoparticles as transfection agents for plasmid DNA
WO2023054241A1 (ja) 核酸を脳組織に送達するために用いられる脂質ナノ粒子
WO2005030835A1 (ja) ポリエチレングリコール誘導体及びこれを膜構成成分とする薬物担体