JPWO2023162456A5 - - Google Patents
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- JPWO2023162456A5 JPWO2023162456A5 JP2023528145A JP2023528145A JPWO2023162456A5 JP WO2023162456 A5 JPWO2023162456 A5 JP WO2023162456A5 JP 2023528145 A JP2023528145 A JP 2023528145A JP 2023528145 A JP2023528145 A JP 2023528145A JP WO2023162456 A5 JPWO2023162456 A5 JP WO2023162456A5
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- JP
- Japan
- Prior art keywords
- formula
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 206010028980 Neoplasm Diseases 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims 1
- 230000007730 Akt signaling Effects 0.000 claims 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 claims 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 1
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 claims 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 1
- LRQKBLKVPFOOQJ-YFKPBYRVSA-N L-norleucine Chemical compound CCCC[C@H]([NH3+])C([O-])=O LRQKBLKVPFOOQJ-YFKPBYRVSA-N 0.000 claims 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- 206010027476 Metastases Diseases 0.000 claims 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 235000003704 aspartic acid Nutrition 0.000 claims 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 125000004122 cyclic group Chemical group 0.000 claims 1
- 235000018417 cysteine Nutrition 0.000 claims 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 claims 1
- 229960000310 isoleucine Drugs 0.000 claims 1
- 230000009401 metastasis Effects 0.000 claims 1
- 230000026731 phosphorylation Effects 0.000 claims 1
- 238000006366 phosphorylation reaction Methods 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022027791 | 2022-02-25 | ||
| JP2022027791 | 2022-02-25 | ||
| PCT/JP2022/047969 WO2023162456A1 (ja) | 2022-02-25 | 2022-12-26 | 癌転移抑制用のｖｉｐｒ２アンタゴニストペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2023162456A1 JPWO2023162456A1 (https=) | 2023-08-31 |
| JP7339471B1 JP7339471B1 (ja) | 2023-09-05 |
| JPWO2023162456A5 true JPWO2023162456A5 (https=) | 2024-01-30 |
Family
ID=87765588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023528145A Active JP7339471B1 (ja) | 2022-02-25 | 2022-12-26 | 癌転移抑制用のｖｉｐｒ２アンタゴニストペプチド |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20250186540A1 (https=) |
| EP (1) | EP4473973A4 (https=) |
| JP (1) | JP7339471B1 (https=) |
| CN (1) | CN118742316A (https=) |
| WO (1) | WO2023162456A1 (https=) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4137502A4 (en) * | 2020-03-30 | 2024-02-28 | Ichimaru Pharcos Co., Ltd. | Vipr2 antagonist peptide |
-
2022
- 2022-12-26 CN CN202280092332.XA patent/CN118742316A/zh active Pending
- 2022-12-26 WO PCT/JP2022/047969 patent/WO2023162456A1/ja not_active Ceased
- 2022-12-26 EP EP22928971.5A patent/EP4473973A4/en active Pending
- 2022-12-26 US US18/841,363 patent/US20250186540A1/en active Pending
- 2022-12-26 JP JP2023528145A patent/JP7339471B1/ja active Active
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