JPWO2023118961A5 - - Google Patents
Info
- Publication number
- JPWO2023118961A5 JPWO2023118961A5 JP2024537359A JP2024537359A JPWO2023118961A5 JP WO2023118961 A5 JPWO2023118961 A5 JP WO2023118961A5 JP 2024537359 A JP2024537359 A JP 2024537359A JP 2024537359 A JP2024537359 A JP 2024537359A JP WO2023118961 A5 JPWO2023118961 A5 JP WO2023118961A5
- Authority
- JP
- Japan
- Prior art keywords
- drug conjugate
- appendix
- aryl
- alkyl
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163292101P | 2021-12-21 | 2021-12-21 | |
| US63/292,101 | 2021-12-21 | ||
| PCT/IB2022/000772 WO2023118961A1 (en) | 2021-12-21 | 2022-12-20 | Antibody drug conjugates comprising toxins with polar groups and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2025500342A JP2025500342A (ja) | 2025-01-09 |
| JP2025500342A5 JP2025500342A5 (https=) | 2026-01-06 |
| JPWO2023118961A5 true JPWO2023118961A5 (https=) | 2026-01-06 |
Family
ID=86766932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024537359A Pending JP2025500342A (ja) | 2021-12-21 | 2022-12-20 | 極性基を有する毒素を含む抗体薬物コンジュゲート及びその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230190939A1 (https=) |
| EP (1) | EP4452328A1 (https=) |
| JP (1) | JP2025500342A (https=) |
| KR (1) | KR20240127409A (https=) |
| CN (2) | CN118414170A (https=) |
| WO (1) | WO2023118961A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210068591A (ko) | 2018-10-31 | 2021-06-09 | 주식회사 인투셀 | 융합된 헤테로시클릭 벤조디아제핀 유도체 및 그의 용도 |
| US20250239582A1 (en) | 2024-01-19 | 2025-07-24 | 24M Technologies, Inc. | Systems and methods for preparing semi-solid electrodes |
| WO2025214466A1 (en) * | 2024-04-12 | 2025-10-16 | BeiGene Guangzhou Biologics Manufacturing Co., Ltd. | Targeted pyrrolobenzodiazapine conjugates |
| WO2026059501A1 (en) * | 2024-09-13 | 2026-03-19 | Hummingbird Bioscience Pte. Ltd. | Linker moieties |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5843937A (en) * | 1996-05-23 | 1998-12-01 | Panorama Research, Inc. | DNA-binding indole derivatives, their prodrugs and immunoconjugates as anticancer agents |
| US10131682B2 (en) * | 2012-11-24 | 2018-11-20 | Hangzhou Dac Biotech Co., Ltd. | Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules |
| GB201617466D0 (en) * | 2016-10-14 | 2016-11-30 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
| KR20210068591A (ko) * | 2018-10-31 | 2021-06-09 | 주식회사 인투셀 | 융합된 헤테로시클릭 벤조디아제핀 유도체 및 그의 용도 |
| KR102503143B1 (ko) * | 2019-03-06 | 2023-02-24 | 주식회사 레고켐 바이오사이언스 | 인간 dlk1에 대한 항체를 포함하는 항체 약물 접합체 및 이의 용도 |
-
2022
- 2022-12-20 WO PCT/IB2022/000772 patent/WO2023118961A1/en not_active Ceased
- 2022-12-20 US US18/084,739 patent/US20230190939A1/en active Pending
- 2022-12-20 EP EP22910281.9A patent/EP4452328A1/en active Pending
- 2022-12-20 CN CN202280084624.9A patent/CN118414170A/zh active Pending
- 2022-12-20 CN CN202411879063.9A patent/CN119838020A/zh active Pending
- 2022-12-20 JP JP2024537359A patent/JP2025500342A/ja active Pending
- 2022-12-20 KR KR1020247024345A patent/KR20240127409A/ko active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20220306759A1 (en) | Anti-cd71 antibodies, activatable anti-cd71 antibodies, and methods of use thereof | |
| JP7171617B2 (ja) | 抗SIRPα抗体 | |
| US9828428B2 (en) | Anti-IL-13 receptor alpha 2 antibodies and antibody-drug conjugates | |
| AU2016232839B2 (en) | CD48 antibodies and conjugates thereof | |
| JP2021531764A5 (https=) | ||
| JP2020501531A5 (https=) | ||
| US20200157224A1 (en) | Multi-specific antibodies and methods of making and using thereof | |
| CN107735093A (zh) | Cd123抗体和其结合物 | |
| IL321912A (en) | Human CD3-binding antibody | |
| AU2026202052A1 (en) | Anti-c-Met antibody drug conjugates | |
| CA3198667A1 (en) | Antibody-drug conjugate and application thereof | |
| KR20250127137A (ko) | 항-cmet 항체, 항체-약물 접합체, 이의 제조 방법 및 용도 | |
| CN105828841A (zh) | 抗-efna4抗体-药物缀合物 | |
| JPWO2023118961A5 (https=) | ||
| US20190389960A1 (en) | Compositions and methods for c1q targeted therapy | |
| JPWO2019228514A5 (https=) | ||
| US20240417457A1 (en) | Antibodies directed against alpha-folate receptor | |
| WO2026057074A1 (zh) | 抗liv-1抗体-药物偶联物的组合疗法 | |
| WO2026057076A1 (zh) | 基于抗liv-1抗体-药物偶联物的耐药癌症的治疗 | |
| CN118302200A (zh) | 用于治疗癌症的b7-h4抗体-药物缀合物 | |
| NZ761454B2 (en) | Anti-ctla4 antibodies and uses thereof | |
| JPWO2022082066A5 (https=) | ||
| Murray et al. | Therapeutic anticancer antibodies | |
| JPWO2022242680A5 (https=) | ||
| JPWO2023092099A5 (https=) |